GREMLIN Database
HUTU - Urocanate hydratase
UniProt: P25503 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 552 (541)
Sequences: 1186 (336)
Seq/√Len: 14.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
20_G23_Q4.9771.00
41_K44_D4.7981.00
208_C235_A3.9811.00
182_V187_G3.8811.00
200_D204_E3.8091.00
426_R511_D3.7471.00
371_R429_E3.7220.99
210_R221_W3.5790.99
371_R424_L3.4700.99
468_V484_F3.4610.99
152_L256_I3.4350.99
123_M463_V3.2110.98
290_L294_L3.1960.98
142_L397_V3.1650.98
430_L434_V3.1600.98
67_S87_M3.1550.98
57_D60_A3.0940.98
282_R286_D3.0810.98
206_K398_T3.0410.98
113_H116_E2.8910.97
216_E250_R2.8500.97
242_E273_E2.8330.97
19_L72_K2.8250.96
167_L244_H2.8210.96
225_A232_L2.7800.96
162_K229_G2.7250.96
196_E200_D2.7180.96
86_G527_I2.6500.95
308_A312_K2.6490.95
27_L65_E2.6260.95
246_T250_R2.5950.94
190_I222_A2.5520.94
246_T249_N2.5460.94
100_A103_V2.5440.94
31_R65_E2.5360.93
477_A520_S2.5200.93
464_G496_L2.4440.92
167_L309_F2.4230.92
290_L293_R2.4230.92
245_H301_K2.3940.91
22_E480_S2.3940.91
217_E221_W2.3810.91
424_L430_L2.3520.91
200_D211_K2.3330.90
12_R37_E2.3200.90
375_L420_A2.3110.90
212_T221_W2.3080.90
426_R508_E2.2900.89
323_I338_F2.2560.89
224_E228_A2.2480.88
70_T547_I2.2320.88
138_S142_L2.1920.87
116_E120_K2.1750.87
165_L252_V2.1660.86
169_A240_A2.1580.86
58_W61_F2.1390.86
383_N413_E2.1360.86
182_V189_V2.1070.85
443_C526_I2.0780.84
196_E211_K2.0720.84
188_V234_I2.0510.83
334_N337_D2.0500.83
165_L222_A2.0350.83
63_A66_H2.0310.83
93_Q512_E2.0260.82
23_Q26_V2.0240.82
300_K332_L2.0160.82
156_H315_I2.0090.82
8_I61_F2.0020.82
9_R12_R1.9970.81
365_D431_K1.9690.80
287_T290_L1.9640.80
30_L65_E1.9600.80
271_V280_A1.9580.80
153_A187_G1.9450.80
257_V316_V1.9420.80
370_Y394_Q1.9370.79
417_M421_I1.9140.78
211_K237_L1.9100.78
113_H463_V1.8810.77
504_A514_L1.8800.77
509_L513_R1.8780.77
151_E154_R1.8600.76
138_S397_V1.8550.76
304_E308_A1.8250.75
88_F523_G1.8110.74
222_A234_I1.8000.74
424_L429_E1.7850.73
20_G26_V1.7840.73
27_L31_R1.7630.72
367_A370_Y1.7600.72
502_A514_L1.7570.72
151_E155_Q1.7570.72
275_Y294_L1.7440.72
423_E427_T1.7420.71
306_M316_V1.7390.71
296_K326_V1.7390.71
199_I237_L1.7210.70
484_F496_L1.7170.70
308_A311_Q1.7120.70
311_Q334_N1.7060.70
248_L308_A1.7050.70
192_V244_H1.6990.69
245_H249_N1.6950.69
88_F473_V1.6940.69
236_L243_V1.6920.69
165_L190_I1.6810.69
73_N92_P1.6770.68
79_V133_W1.6660.68
471_A484_F1.6470.67
188_V222_A1.6440.67
294_L297_Q1.6370.66
17_E69_K1.6330.66
192_V238_G1.6320.66
377_K391_D1.6280.66
193_E237_L1.6240.66
51_I492_M1.5920.64
248_L312_K1.5870.64
371_R427_T1.5780.64
366_P403_P1.5710.63
113_H123_M1.5700.63
375_L424_L1.5700.63
309_F316_V1.5580.62
377_K390_I1.5450.62
536_R539_E1.5410.62
341_F441_L1.5360.61
244_H302_H1.5290.61
194_V271_V1.5200.61
91_H94_A1.5200.61
103_V468_V1.5190.60
419_L511_D1.5150.60
210_R217_E1.5140.60
214_S217_E1.5110.60
20_G73_N1.5100.60
473_V524_M1.5090.60
374_A394_Q1.5060.60
171_L208_C1.5010.60
171_L193_E1.5000.59
196_E213_A1.4980.59
500_M514_L1.4830.59
212_T218_A1.4700.58
192_V243_V1.4620.57
110_D113_H1.4580.57
153_A161_L1.4530.57
67_S77_L1.4530.57
40_E173_G1.4520.57
166_T256_I1.4390.56
490_V495_S1.4340.56
165_L226_K1.4330.56
273_E301_K1.4310.56
103_V496_L1.4230.55
183_T209_D1.3820.53
415_K519_T1.3790.53
25_A503_V1.3780.53
376_L417_M1.3780.53
266_P299_M1.3700.52
307_L332_L1.3570.52
104_L117_L1.3560.52
221_W232_L1.3550.52
223_E226_K1.3490.51
199_I211_K1.3470.51
325_Q329_D1.3440.51
232_L276_S1.3410.51
116_E119_K1.3410.51
222_A243_V1.3330.50
162_K186_E1.3110.49
512_E515_A1.2930.48
411_Y523_G1.2920.48
219_L243_V1.2810.48
171_L237_L1.2800.47
248_L309_F1.2780.47
92_P509_L1.2770.47
524_M527_I1.2740.47
134_I437_G1.2720.47
477_A502_A1.2650.47
380_F409_L1.2650.47
190_I247_L1.2640.47
103_V484_F1.2620.46
179_P191_A1.2560.46
374_A378_E1.2510.46
266_P326_V1.2430.45
26_V480_S1.2400.45
257_V309_F1.2300.45
10_A402_L1.2290.45
161_L187_G1.2270.45
328_K333_E1.2260.44
107_K494_Y1.2260.44
221_W230_K1.2250.44
537_A541_A1.2240.44
472_L475_T1.2170.44
326_V329_D1.2100.44
195_D198_R1.2100.44
93_Q509_L1.2100.44
479_A482_V1.2000.43
179_P233_S1.1980.43
153_A160_S1.1950.43
509_L512_E1.1880.42
53_K118_E1.1850.42
219_L247_L1.1750.42
109_A486_H1.1690.41
72_K87_M1.1690.41
150_A185_N1.1660.41
380_F417_M1.1650.41
88_F527_I1.1560.41
443_C524_M1.1520.41
371_R430_L1.1520.41
192_V245_H1.1510.40
508_E512_E1.1490.40
28_R402_L1.1470.40
66_H70_T1.1460.40
160_S186_E1.1430.40
51_I118_E1.1290.39
118_E492_M1.1260.39
338_F344_A1.1260.39
61_F434_V1.1180.39
8_I31_R1.1170.39
425_V430_L1.1130.38
71_L87_M1.0940.37
115_H118_E1.0770.37
55_A64_I1.0750.36
511_D515_A1.0700.36
11_N31_R1.0650.36
213_A217_E1.0620.36
60_A83_K1.0610.36
276_S279_E1.0550.35
168_T191_A1.0540.35
166_T182_V1.0490.35
348_P351_C1.0460.35
360_A404_S1.0440.35
390_I421_I1.0400.35
166_T187_G1.0400.35
381_P387_H1.0310.34
201_K204_E1.0300.34
540_V544_Q1.0240.34
58_W65_E1.0150.33
421_I436_I1.0120.33
379_L420_A1.0120.33
248_L253_K1.0100.33
244_H257_V1.0090.33
232_L396_K1.0070.33
183_T189_V1.0070.33
74_D92_P1.0040.33
190_I214_S1.0040.33
61_F65_E1.0010.33
104_L110_D0.9980.33
199_I235_A0.9940.32
508_E511_D0.9930.32
192_V257_V0.9890.32
182_V188_V0.9880.32
306_M338_F0.9850.32
21_W24_E0.9820.32
31_R61_F0.9790.32
329_D494_Y0.9780.32
392_M395_E0.9750.32
18_C24_E0.9730.31
23_Q73_N0.9710.31
375_L421_I0.9680.31
367_A431_K0.9650.31
125_Y495_S0.9600.31
72_K75_E0.9560.31
280_A291_Y0.9560.31
153_A185_N0.9510.30
18_C69_K0.9500.30
192_V241_A0.9490.30
107_K110_D0.9460.30
325_Q494_Y0.9450.30
253_K309_F0.9430.30
210_R232_L0.9400.30
41_K46_I0.9390.30
223_E227_L0.9390.30
527_I546_I0.9380.30
293_R297_Q0.9370.30
216_E246_T0.9360.30
473_V527_I0.9350.30
242_E274_G0.9330.30
424_L427_T0.9330.30
243_V246_T0.9320.30
167_L257_V0.9310.29
51_I115_H0.9300.29
167_L247_L0.9280.29
182_V186_E0.9250.29
242_E245_H0.9240.29
131_G318_D0.9230.29
183_T396_K0.9230.29
206_K395_E0.9210.29
216_E503_V0.9210.29
80_Q469_L0.9200.29
113_H120_K0.9200.29
165_L188_V0.9180.29
303_V323_I0.9150.29
371_R431_K0.9140.29
362_L435_V0.9130.29
203_I211_K0.9080.28
423_E429_E0.9060.28
103_V464_G0.9060.28
443_C540_V0.9040.28
325_Q450_N0.9030.28
164_T255_D0.9000.28
53_K216_E0.9000.28
27_L30_L0.9000.28
468_V496_L0.8990.28
293_R508_E0.8970.28
23_Q480_S0.8970.28
328_K334_N0.8930.28
64_I77_L0.8870.28
123_M492_M0.8860.27
234_I381_P0.8850.27
83_K531_D0.8830.27
262_S269_G0.8790.27
457_K535_E0.8770.27
167_L240_A0.8770.27
190_I234_I0.8750.27
91_H513_R0.8750.27
371_R375_L0.8680.27
214_S221_W0.8660.27
240_A323_I0.8650.27
419_L426_R0.8640.27
67_S547_I0.8630.26
271_V281_D0.8630.26
168_T189_V0.8620.26
67_S70_T0.8620.26
50_G96_R0.8600.26
186_E231_P0.8580.26
448_S490_V0.8510.26
142_L201_K0.8500.26
219_L246_T0.8480.26
75_E87_M0.8410.26
8_I58_W0.8410.26
210_R224_E0.8390.25
21_W28_R0.8370.25
242_E301_K0.8360.25
152_L157_F0.8350.25
153_A164_T0.8310.25
102_S123_M0.8300.25
196_E237_L0.8300.25
295_A300_K0.8240.25
390_I496_L0.8240.25
27_L69_K0.8230.25
339_P344_A0.8220.25
530_A538_V0.8200.25
468_V471_A0.8180.25
369_I399_F0.8170.25
118_E463_V0.8160.25
304_E332_L0.8150.24
179_P208_C0.8140.24
93_Q513_R0.8130.24
179_P425_V0.8130.24
212_T217_E0.8120.24
242_E247_L0.8110.24
182_V185_N0.8090.24
206_K396_K0.8080.24
126_G489_G0.8080.24
215_I236_L0.8070.24
411_Y519_T0.8060.24
375_L379_L0.8050.24
153_A484_F0.8040.24
29_M435_V0.8020.24
198_R262_S0.8010.24
253_K314_S0.7980.24
74_D89_R0.7950.24
13_G21_W0.7950.24
248_L305_A0.7940.24
142_L323_I0.7940.24
101_N131_G0.7940.24
128_M448_S0.7940.24
297_Q539_E0.7850.23
371_R374_A0.7850.23
90_T473_V0.7830.23
20_G480_S0.7810.23
26_V481_W0.7780.23
160_S185_N0.7780.23
451_R491_G0.7760.23
351_C437_G0.7750.23
375_L417_M0.7750.23
156_H317_F0.7750.23
11_N17_E0.7740.23
423_E511_D0.7730.23
244_H316_V0.7710.23
262_S338_F0.7690.23
241_A245_H0.7680.23
39_A49_G0.7680.23
280_A284_R0.7680.23
138_S323_I0.7670.23
283_L434_V0.7670.23
472_L484_F0.7660.23
215_I219_L0.7630.22
372_T421_I0.7630.22
411_Y520_S0.7600.22
292_V296_K0.7590.22
18_C193_E0.7560.22
409_L417_M0.7550.22
427_T430_L0.7550.22
360_A535_E0.7550.22
192_V236_L0.7510.22
341_F408_W0.7510.22
304_E333_E0.7500.22
418_G518_L0.7500.22
87_M339_P0.7480.22
167_L346_I0.7470.22
65_E69_K0.7450.22
18_C23_Q0.7440.22
271_V291_Y0.7420.22
18_C27_L0.7420.22
282_R287_T0.7410.22
464_G492_M0.7380.21
169_A189_V0.7380.21
474_N517_V0.7380.21
152_L248_L0.7370.21
322_N494_Y0.7330.21
377_K387_H0.7310.21
544_Q547_I0.7290.21
387_H391_D0.7280.21
279_E282_R0.7260.21
164_T182_V0.7260.21
457_K538_V0.7250.21
196_E277_L0.7230.21
24_E28_R0.7210.21
502_A507_S0.7210.21
376_L383_N0.7200.21
319_Y451_R0.7200.21
448_S451_R0.7130.21
540_V543_E0.7120.21
125_Y468_V0.7120.21
367_A371_R0.7080.20
431_K434_V0.7080.20
420_A423_E0.7080.20
507_S511_D0.7070.20
100_A496_L0.7070.20
415_K419_L0.7070.20
98_L471_A0.7070.20
221_W234_I0.7070.20
341_F351_C0.7050.20
274_G297_Q0.7020.20
247_L254_I0.7000.20
348_P352_E0.7000.20
162_K227_L0.6990.20
378_E508_E0.6990.20
193_E502_A0.6980.20
390_I523_G0.6970.20
275_Y283_L0.6950.20
149_F475_T0.6950.20
15_E168_T0.6920.20
390_I417_M0.6920.20
92_P475_T0.6890.20
241_A257_V0.6880.20
156_H513_R0.6870.20
283_L290_L0.6860.20
421_I480_S0.6860.20
132_S481_W0.6860.20
132_S483_S0.6840.20
208_C421_I0.6840.20
17_E27_L0.6820.19
44_D173_G0.6810.19
204_E374_A0.6810.19
480_S496_L0.6800.19
210_R214_S0.6800.19
231_P396_K0.6780.19
152_L345_Y0.6780.19
37_E204_E0.6780.19
319_Y452_E0.6770.19
443_C473_V0.6760.19
57_D83_K0.6760.19
89_R515_A0.6760.19
160_S164_T0.6760.19
303_V327_A0.6760.19
106_P464_G0.6750.19
204_E211_K0.6750.19
257_V305_A0.6710.19
187_G222_A0.6710.19
317_F484_F0.6700.19
49_G52_G0.6700.19
284_R291_Y0.6690.19
354_K443_C0.6690.19
192_V360_A0.6690.19
53_K62_H0.6690.19
86_G524_M0.6680.19
46_I483_S0.6660.19
205_T398_T0.6640.19
245_H298_S0.6640.19
371_R420_A0.6630.19
115_H119_K0.6630.19
106_P171_L0.6630.19
298_S383_N0.6620.19
31_R348_P0.6620.19
228_A434_V0.6610.19
273_E298_S0.6600.19
222_A226_K0.6600.19
49_G127_Q0.6600.19
536_R540_V0.6600.19
504_A511_D0.6590.19
9_R162_K0.6570.19
287_T293_R0.6570.19
235_A533_G0.6560.19
473_V520_S0.6560.19
192_V305_A0.6560.19
253_K312_K0.6550.19
106_P486_H0.6540.19
53_K115_H0.6530.18
79_V287_T0.6520.18
295_A299_M0.6510.18
208_C237_L0.6500.18
380_F413_E0.6500.18
213_A221_W0.6480.18
262_S318_D0.6480.18
166_T258_T0.6480.18
93_Q502_A0.6470.18
162_K228_A0.6450.18
267_L292_V0.6450.18
188_V232_L0.6450.18
416_K424_L0.6440.18
379_L417_M0.6440.18
275_Y282_R0.6440.18
100_A241_A0.6430.18
454_E469_L0.6430.18
310_Q314_S0.6420.18
148_T319_Y0.6410.18
419_L423_E0.6410.18
72_K193_E0.6410.18
51_I123_M0.6400.18
153_A182_V0.6390.18
451_R478_G0.6380.18
325_Q328_K0.6380.18
169_A192_V0.6380.18
445_S529_H0.6370.18
193_E328_K0.6360.18
215_I503_V0.6360.18
47_V54_A0.6350.18
376_L420_A0.6340.18
22_E503_V0.6340.18
262_S372_T0.6330.18
273_E305_A0.6330.18
325_Q330_E0.6320.18
162_K230_K0.6320.18
202_R406_I0.6310.18
60_A193_E0.6310.18
191_A199_I0.6310.18
480_S503_V0.6290.18
182_V191_A0.6280.18
219_L226_K0.6270.18
156_H345_Y0.6260.18
131_G485_H0.6260.18
16_L27_L0.6250.18
220_A294_L0.6250.18
319_Y491_G0.6240.18
194_V243_V0.6240.18
46_I252_V0.6230.18
43_E242_E0.6230.18
435_V481_W0.6210.17
159_G289_E0.6210.17
173_G262_S0.6200.17
111_W469_L0.6200.17
134_I348_P0.6190.17
300_K304_E0.6170.17
167_L219_L0.6170.17
240_A244_H0.6160.17
481_W501_V0.6160.17
271_V284_R0.6150.17
302_H306_M0.6150.17
221_W224_E0.6140.17
157_F314_S0.6140.17
283_L291_Y0.6130.17
160_S182_V0.6120.17
403_P454_E0.6110.17
217_E234_I0.6110.17
157_F315_I0.6100.17
31_R58_W0.6100.17
192_V229_G0.6080.17
74_D535_E0.6080.17
291_Y322_N0.6080.17
199_I203_I0.6070.17
23_Q27_L0.6060.17
100_A468_V0.6060.17
86_G262_S0.6060.17
282_R293_R0.6060.17
411_Y540_V0.6050.17
148_T452_E0.6050.17
244_H309_F0.6050.17
25_A215_I0.6050.17
241_A305_A0.6040.17
289_E297_Q0.6030.17
171_L199_I0.6030.17
361_A369_I0.6030.17
171_L269_G0.6030.17
118_E123_M0.6030.17
219_L305_A0.5990.17
156_H322_N0.5980.17
194_V280_A0.5970.17
437_G501_V0.5970.17
348_P532_A0.5970.17
354_K477_A0.5970.17
155_Q344_A0.5960.17
300_K430_L0.5930.17
535_E539_E0.5920.17
85_V454_E0.5920.17
245_H248_L0.5910.17
90_T477_A0.5900.16
390_I464_G0.5890.16
354_K417_M0.5880.16
316_V338_F0.5850.16
165_L189_V0.5850.16
86_G417_M0.5840.16
379_L421_I0.5840.16
215_I247_L0.5830.16
452_E491_G0.5830.16
219_L248_L0.5820.16
182_V222_A0.5820.16
360_A437_G0.5810.16
440_H451_R0.5810.16
96_R127_Q0.5810.16
167_L316_V0.5810.16
128_M141_I0.5800.16
468_V472_L0.5800.16
464_G484_F0.5800.16
157_F256_I0.5790.16
419_L515_A0.5790.16
416_K430_L0.5790.16
230_K395_E0.5780.16
46_I103_V0.5780.16
78_L483_S0.5770.16
301_K304_E0.5760.16
50_G132_S0.5760.16
56_R61_F0.5740.16
217_E378_E0.5730.16
290_L416_K0.5730.16
378_E543_E0.5730.16
168_T193_E0.5730.16
85_V484_F0.5730.16
10_A28_R0.5720.16
79_V94_A0.5720.16
397_V413_E0.5720.16
522_P529_H0.5710.16
114_F317_F0.5710.16
210_R293_R0.5710.16
182_V421_I0.5710.16
46_I387_H0.5700.16
379_L416_K0.5700.16
12_R364_G0.5700.16
164_T187_G0.5690.16
134_I501_V0.5690.16
227_L297_Q0.5690.16
317_F425_V0.5690.16
450_N494_Y0.5680.16
450_N463_V0.5670.16
376_L390_I0.5660.16
94_A490_V0.5650.16
15_E92_P0.5650.16
88_F430_L0.5650.16
46_I281_D0.5640.16
213_A237_L0.5640.16
222_A417_M0.5630.16
408_W441_L0.5630.16
152_L434_V0.5610.16
290_L304_E0.5610.16
384_K391_D0.5610.16
418_G500_M0.5610.16
51_I268_I0.5600.16
41_K173_G0.5600.16
76_T239_N0.5600.16
208_C211_K0.5590.16
262_S406_I0.5590.16
142_L398_T0.5590.16
141_I451_R0.5580.16
153_A243_V0.5580.16
210_R230_K0.5570.16
46_I51_I0.5570.16
293_R304_E0.5570.16
192_V302_H0.5570.16
312_K374_A0.5570.16
217_E230_K0.5560.15
92_P513_R0.5550.15
53_K57_D0.5540.15
245_H305_A0.5540.15
161_L188_V0.5540.15
51_I326_V0.5530.15
218_A236_L0.5530.15
473_V547_I0.5530.15
128_M451_R0.5530.15
141_I372_T0.5520.15
128_M319_Y0.5520.15
215_I250_R0.5520.15
282_R427_T0.5510.15
372_T379_L0.5510.15
124_M132_S0.5510.15
134_I351_C0.5510.15
196_E214_S0.5510.15
192_V316_V0.5500.15
237_L298_S0.5500.15
221_W228_A0.5500.15
169_A244_H0.5500.15
167_L222_A0.5500.15
160_S287_T0.5490.15
299_M323_I0.5480.15
127_Q497_H0.5480.15
131_G501_V0.5480.15
253_K431_K0.5480.15
26_V503_V0.5470.15
185_N421_I0.5460.15
216_E219_L0.5460.15
212_T236_L0.5450.15
70_T87_M0.5440.15
149_F408_W0.5430.15
314_S377_K0.5430.15
46_I173_G0.5430.15
293_R535_E0.5430.15
380_F426_R0.5420.15
448_S491_G0.5420.15
448_S452_E0.5410.15
25_A432_A0.5390.15
123_M532_A0.5390.15
85_V468_V0.5380.15
154_R158_G0.5380.15
26_V99_L0.5380.15
57_D214_S0.5380.15
241_A246_T0.5370.15
193_E211_K0.5370.15
210_R228_A0.5360.15
99_L124_M0.5360.15
238_G305_A0.5360.15
73_N155_Q0.5360.15
248_L297_Q0.5350.15
20_G28_R0.5340.15
169_A507_S0.5330.15
349_L419_L0.5330.15
184_M244_H0.5330.15
228_A535_E0.5310.15
166_T222_A0.5310.15
20_G71_L0.5310.15
213_A216_E0.5310.15
222_A247_L0.5310.15
132_S318_D0.5310.15
151_E500_M0.5300.15
235_A507_S0.5290.15
141_I262_S0.5290.15
93_Q430_L0.5290.15
33_N128_M0.5290.15
375_L381_P0.5280.15
442_D525_G0.5280.15
254_I284_R0.5280.15
464_G523_G0.5280.15
22_E73_N0.5270.15
115_H463_V0.5270.15
228_A395_E0.5260.15
244_H247_L0.5250.15
200_D282_R0.5250.15
74_D457_K0.5250.15
22_E509_L0.5230.15
426_R507_S0.5230.15
275_Y279_E0.5230.15
88_F417_M0.5220.15
106_P481_W0.5220.15
44_D206_K0.5220.15
39_A407_C0.5220.15
158_G543_E0.5210.14
148_T353_G0.5210.14
214_S512_E0.5200.14
269_G322_N0.5200.14
481_W517_V0.5200.14
435_V501_V0.5190.14
79_V99_L0.5190.14
254_I322_N0.5190.14
165_L223_E0.5190.14
376_L394_Q0.5180.14
86_G546_I0.5180.14
76_T471_A0.5180.14
88_F376_L0.5170.14
195_D281_D0.5170.14
215_I305_A0.5160.14
18_C222_A0.5160.14
340_G529_H0.5160.14
319_Y353_G0.5160.14
40_E341_F0.5160.14
187_G234_I0.5160.14
235_A309_F0.5160.14
353_G452_E0.5160.14
312_K416_K0.5150.14
432_A435_V0.5150.14
120_K430_L0.5150.14
225_A288_P0.5150.14
46_I79_V0.5140.14
268_I284_R0.5140.14
167_L184_M0.5140.14
476_A502_A0.5130.14
58_W62_H0.5130.14
188_V391_D0.5130.14
108_W462_A0.5120.14
226_K300_K0.5110.14
37_E110_D0.5110.14
162_K370_Y0.5110.14
413_E417_M0.5110.14
303_V338_F0.5110.14
351_C441_L0.5110.14
431_K547_I0.5100.14
452_E478_G0.5100.14
190_I231_P0.5090.14
152_L314_S0.5090.14
101_N128_M0.5090.14
219_L236_L0.5090.14
226_K252_V0.5060.14
116_E123_M0.5060.14
437_G481_W0.5050.14
343_P501_V0.5050.14
437_G483_S0.5050.14
210_R216_E0.5040.14
138_S299_M0.5030.14
197_K507_S0.5020.14
171_L211_K0.5020.14
240_A430_L0.5020.14
230_K249_N0.5010.14
127_Q491_G0.5010.14
184_M240_A0.5010.14
19_L120_K0.5000.14
290_L543_E0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2fknA 2 0.9891 100 0.014 Contact Map
1uwkA 2 0.9946 100 0.015 Contact Map
1x87A 2 0.9257 100 0.017 Contact Map
3p2yA 2 0.5362 65.3 0.986 Contact Map
1wmaA 1 0.3841 65.2 0.986 Contact Map
1x13A 2 0.5362 63.2 0.986 Contact Map
4r1nA 2 0.4275 60.5 0.986 Contact Map
2wzmA 1 0.462 55.1 0.987 Contact Map
3gdhA 1 0.3551 53.5 0.987 Contact Map
1wekA 5 0.3188 52.6 0.987 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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