BSAP - BACSU - GREMLIN Contacts

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BSAP - Aminopeptidase YwaD

UniProt:	P25152	Sequences: MKKLLTVMTMAVLTAGTLLLPAQSVTPAAHAVQISNSERELPFKAKHAYSTISQLSEAIGPRIAGTAAEKKSALLIASSMRKLKLDVKVQRFNIPDRLEGTLSSAGRDILLQAASGSAPTEEQGLTAPLYNAGLGYQKDFTADAKGKIALISRGDLTYYEKAKNAEAAGAKAVIIYNNKESLVPMTPNLSGNKVGIPVVGIKKEDGEALTQQKEATLKLKAFTNQTSQNIIGIKKPKNIKHPDIVYVTAHYDSVPFSPGANDNGSGTSVMLEMARVLKSVPSDKEIRFIAFGAEELGLLGSSHYVDHLSEKELKRSEVNFNLDMVGTSWEKASELYVNTLDGQSNYVWESSRTAAEKIGFDSLSLTQGGSSDHVPFHEAGIDSANFIWGDPETEEVEPWYHTPEDSIEHISKERLQQAGDLVTAAVYEAVKKEKKPKTIKKQMKAKASDIFEDIK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	455 (400)
Sequences:	4119 (3119)
Seq/√Len:	155.9

BACSU - BSAP
HALSA - Q9HRR8 Q9HNP7
SULSO - Q7LXL7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
79_S	82_K	4.125	1.00
77_A	81_R	3.937	1.00
399_W	404_E	3.597	1.00
77_A	89_V	3.551	1.00
144_A	149_A	3.489	1.00
80_M	290_A	3.388	1.00
151_I	173_V	3.305	1.00
239_I	283_D	3.234	1.00
128_P	147_K	3.122	1.00
247_V	426_V	3.112	1.00
272_E	275_R	2.766	1.00
126_T	216_T	2.679	1.00
91_R	226_T	2.664	1.00
89_V	228_Q	2.657	1.00
132_A	151_I	2.628	1.00
148_I	172_A	2.627	1.00
318_V	429_A	2.534	1.00
51_T	75_L	2.464	1.00
127_A	171_K	2.429	1.00
248_T	319_N	2.420	1.00
233_I	287_R	2.393	1.00
67_A	71_K	2.378	1.00
305_V	379_A	2.327	1.00
73_A	230_I	2.263	1.00
303_H	307_H	2.241	1.00
124_G	218_K	2.218	1.00
86_D	235_K	2.204	1.00
124_G	216_T	2.200	1.00
69_E	292_G	2.189	1.00
74_L	77_A	2.172	1.00
90_Q	308_L	2.143	1.00
416_Q	420_D	2.128	1.00
237_K	283_D	2.110	1.00
92_F	292_G	2.091	1.00
70_K	74_L	2.070	1.00
270_M	290_A	2.068	1.00
267_T	290_A	2.061	1.00
146_G	171_K	2.060	1.00
163_K	167_A	2.058	1.00
76_I	251_Y	2.045	1.00
149_A	170_A	2.020	1.00
244_I	287_R	2.014	1.00
235_K	241_H	2.009	1.00
244_I	285_E	1.998	1.00
269_V	325_V	1.987	1.00
242_P	315_R	1.943	1.00
243_D	284_K	1.924	1.00
129_L	150_L	1.923	1.00
313_L	381_I	1.918	1.00
69_E	251_Y	1.914	1.00
231_I	289_I	1.889	1.00
74_L	78_S	1.853	1.00
53_S	407_I	1.848	1.00
44_K	47_H	1.825	1.00
52_I	264_G	1.820	1.00
128_P	214_E	1.799	1.00
301_S	375_P	1.784	1.00
174_I	201_I	1.778	1.00
164_N	167_A	1.770	1.00
126_T	214_E	1.745	1.00
164_N	168_A	1.730	1.00
64_A	293_A	1.715	1.00
76_I	290_A	1.715	1.00
269_V	419_G	1.705	1.00
93_N	226_T	1.694	1.00
240_K	243_D	1.693	1.00
130_Y	144_A	1.653	1.00
203_K	207_E	1.648	1.00
172_A	217_L	1.641	1.00
96_D	99_E	1.641	1.00
45_A	416_Q	1.629	1.00
227_S	292_G	1.625	1.00
248_T	291_F	1.618	1.00
291_F	319_N	1.606	1.00
80_M	232_G	1.592	1.00
174_I	199_V	1.578	1.00
49_Y	412_K	1.565	1.00
140_F	164_N	1.549	1.00
78_S	82_K	1.547	1.00
207_E	211_Q	1.544	1.00
305_V	375_P	1.542	1.00
294_E	401_H	1.527	1.00
73_A	251_Y	1.526	1.00
136_Y	139_D	1.526	1.00
77_A	87_V	1.520	1.00
353_T	428_E	1.506	1.00
47_H	272_E	1.479	1.00
185_M	189_L	1.472	1.00
277_L	286_I	1.468	1.00
201_I	205_D	1.456	1.00
249_A	267_T	1.448	1.00
295_E	401_H	1.433	1.00
427_Y	431_K	1.431	1.00
258_P	406_S	1.428	1.00
127_A	148_I	1.417	1.00
233_I	285_E	1.412	1.00
322_L	422_V	1.402	1.00
233_I	244_I	1.402	1.00
262_D	401_H	1.398	1.00
113_A	116_G	1.391	1.00
184_P	187_P	1.390	1.00
262_D	294_E	1.384	1.00
73_A	89_V	1.384	1.00
49_Y	53_S	1.382	1.00
135_G	140_F	1.380	1.00
132_A	142_A	1.376	1.00
117_S	120_T	1.376	1.00
154_G	161_K	1.376	1.00
253_S	259_G	1.375	1.00
83_L	232_G	1.368	1.00
80_M	274_A	1.365	1.00
294_E	400_Y	1.353	1.00
280_V	427_Y	1.349	1.00
184_P	189_L	1.349	1.00
143_D	147_K	1.340	1.00
275_R	279_S	1.340	1.00
205_D	208_A	1.340	1.00
122_E	220_K	1.335	1.00
250_H	262_D	1.333	1.00
140_F	165_A	1.331	1.00
117_S	198_V	1.330	1.00
334_E	337_V	1.324	1.00
91_R	228_Q	1.323	1.00
78_S	81_R	1.316	1.00
70_K	228_Q	1.311	1.00
251_Y	290_A	1.293	1.00
129_L	215_A	1.292	1.00
249_A	270_M	1.292	1.00
282_S	286_I	1.292	1.00
51_T	79_S	1.291	1.00
83_L	271_L	1.289	1.00
304_Y	316_S	1.283	1.00
287_R	304_Y	1.281	1.00
79_S	275_R	1.264	1.00
148_I	215_A	1.260	1.00
86_D	233_I	1.259	1.00
55_L	267_T	1.245	1.00
302_S	306_D	1.243	1.00
313_L	379_A	1.243	1.00
165_A	170_A	1.242	1.00
80_M	271_L	1.235	1.00
144_A	170_A	1.228	1.00
49_Y	407_I	1.222	1.00
90_Q	303_H	1.219	1.00
120_T	124_G	1.219	1.00
250_H	294_E	1.193	1.00
132_A	149_A	1.182	1.00
48_A	419_G	1.182	1.00
72_S	251_Y	1.177	1.00
319_N	383_S	1.169	1.00
246_Y	289_I	1.169	1.00
140_F	168_A	1.166	1.00
349_E	352_R	1.160	1.00
88_K	233_I	1.154	1.00
320_F	426_V	1.154	1.00
263_N	321_N	1.153	1.00
89_V	230_I	1.144	1.00
166_E	195_G	1.142	1.00
37_S	41_L	1.120	1.00
85_L	288_F	1.117	1.00
241_H	285_E	1.115	1.00
63_I	66_T	1.113	1.00
52_I	268_S	1.110	1.00
250_H	323_D	1.107	1.00
309_S	312_E	1.102	0.99
63_I	296_L	1.102	0.99
406_S	409_H	1.099	0.99
286_I	430_V	1.096	0.99
178_N	181_S	1.095	0.99
51_T	271_L	1.092	0.99
277_L	288_F	1.091	0.99
293_A	299_L	1.083	0.99
274_A	288_F	1.079	0.99
333_S	337_V	1.072	0.99
162_A	173_V	1.067	0.99
73_A	228_Q	1.067	0.99
47_H	275_R	1.066	0.99
208_A	212_Q	1.065	0.99
236_P	285_E	1.064	0.99
304_Y	310_E	1.063	0.99
79_S	83_L	1.060	0.99
161_K	165_A	1.059	0.99
129_L	174_I	1.040	0.99
229_N	300_G	1.040	0.99
114_A	117_S	1.039	0.99
101_T	218_K	1.035	0.99
334_E	338_N	1.033	0.99
152_S	210_T	1.033	0.99
90_Q	307_H	1.027	0.99
85_L	234_K	1.027	0.99
51_T	272_E	1.026	0.99
262_D	400_Y	1.025	0.99
303_H	306_D	1.024	0.99
186_T	189_L	1.021	0.99
234_K	282_S	1.019	0.99
97_R	100_G	1.015	0.99
90_Q	229_N	1.007	0.99
129_L	209_L	1.006	0.99
131_N	213_K	1.004	0.99
60_G	67_A	1.004	0.99
236_P	284_K	1.001	0.99
346_Y	350_S	0.997	0.99
261_N	324_M	0.995	0.99
43_F	276_V	0.993	0.99
83_L	278_K	0.991	0.99
295_E	400_Y	0.988	0.99
68_A	71_K	0.987	0.99
137_Q	168_A	0.986	0.99
341_D	345_N	0.985	0.99
186_T	190_S	0.983	0.99
85_L	232_G	0.981	0.99
291_F	376_F	0.980	0.99
107_R	208_A	0.978	0.99
158_Y	175_I	0.977	0.99
273_M	426_V	0.973	0.99
142_A	149_A	0.972	0.99
189_L	193_K	0.968	0.99
247_V	270_M	0.966	0.99
85_L	274_A	0.962	0.99
132_A	173_V	0.955	0.99
332_A	337_V	0.944	0.98
208_A	211_Q	0.941	0.98
187_P	190_S	0.940	0.98
377_H	383_S	0.939	0.98
248_T	289_I	0.939	0.98
231_I	287_R	0.931	0.98
273_M	423_T	0.926	0.98
282_S	285_E	0.926	0.98
174_I	215_A	0.919	0.98
116_G	119_P	0.918	0.98
199_V	219_L	0.918	0.98
399_W	409_H	0.918	0.98
98_L	222_F	0.917	0.98
250_H	295_E	0.913	0.98
131_N	152_S	0.911	0.98
138_K	141_T	0.907	0.98
121_E	124_G	0.906	0.98
250_H	401_H	0.905	0.98
240_K	283_D	0.903	0.98
113_A	118_A	0.901	0.98
219_L	223_T	0.901	0.98
60_G	256_F	0.899	0.98
261_N	327_T	0.896	0.98
50_S	53_S	0.896	0.98
202_K	205_D	0.896	0.98
88_K	231_I	0.895	0.98
352_R	356_E	0.891	0.98
129_L	172_A	0.891	0.98
103_S	216_T	0.889	0.98
319_N	376_F	0.887	0.98
261_N	399_W	0.883	0.98
135_G	139_D	0.880	0.97
45_A	49_Y	0.876	0.97
36_N	40_E	0.874	0.97
234_K	288_F	0.874	0.97
32_V	36_N	0.873	0.97
236_P	282_S	0.873	0.97
272_E	276_V	0.873	0.97
144_A	168_A	0.872	0.97
247_V	288_F	0.865	0.97
302_S	375_P	0.864	0.97
50_S	54_Q	0.863	0.97
165_A	169_G	0.858	0.97
80_M	288_F	0.857	0.97
155_D	159_Y	0.857	0.97
234_K	278_K	0.856	0.97
51_T	83_L	0.852	0.97
134_L	152_S	0.850	0.97
206_G	210_T	0.849	0.97
355_A	362_S	0.848	0.97
388_W	418_A	0.847	0.97
355_A	421_L	0.846	0.97
131_N	210_T	0.844	0.97
109_I	112_Q	0.842	0.97
31_A	34_I	0.839	0.97
49_Y	411_S	0.838	0.97
46_K	50_S	0.835	0.97
64_A	296_L	0.834	0.97
67_A	70_K	0.834	0.97
246_Y	319_N	0.834	0.97
74_L	89_V	0.834	0.97
153_R	158_Y	0.833	0.96
135_G	151_I	0.831	0.96
294_E	371_S	0.830	0.96
301_S	372_D	0.826	0.96
162_A	198_V	0.823	0.96
370_S	400_Y	0.818	0.96
305_V	376_F	0.814	0.96
373_H	385_N	0.813	0.96
361_D	364_S	0.813	0.96
47_H	50_S	0.812	0.96
250_H	372_D	0.812	0.96
185_M	188_N	0.809	0.96
349_E	353_T	0.807	0.96
345_N	348_W	0.806	0.96
35_S	38_E	0.803	0.96
135_G	165_A	0.803	0.96
360_F	363_L	0.799	0.96
294_E	321_N	0.798	0.96
294_E	298_L	0.798	0.96
351_S	355_A	0.797	0.95
359_G	363_L	0.796	0.95
277_L	423_T	0.793	0.95
316_S	381_I	0.792	0.95
106_G	111_L	0.790	0.95
259_G	405_D	0.788	0.95
69_E	76_I	0.788	0.95
291_F	301_S	0.787	0.95
148_I	217_L	0.787	0.95
217_L	221_A	0.786	0.95
59_I	71_K	0.785	0.95
240_K	433_E	0.785	0.95
355_A	358_I	0.783	0.95
245_V	429_A	0.781	0.95
312_E	315_R	0.780	0.95
335_L	338_N	0.779	0.95
350_S	354_A	0.778	0.95
399_W	402_T	0.778	0.95
162_A	189_L	0.774	0.95
261_N	397_E	0.771	0.95
407_I	412_K	0.768	0.94
40_E	424_A	0.765	0.94
54_Q	71_K	0.763	0.94
140_F	144_A	0.761	0.94
51_T	275_R	0.760	0.94
287_R	311_K	0.760	0.94
55_L	264_G	0.757	0.94
309_S	379_A	0.756	0.94
250_H	321_N	0.755	0.94
153_R	177_N	0.754	0.94
345_N	349_E	0.754	0.94
262_D	372_D	0.751	0.94
190_S	193_K	0.751	0.94
54_Q	57_E	0.750	0.94
133_G	139_D	0.750	0.94
34_I	37_S	0.747	0.94
295_E	301_S	0.746	0.94
185_M	190_S	0.744	0.94
39_R	423_T	0.744	0.94
262_D	321_N	0.742	0.93
295_E	298_L	0.740	0.93
105_A	212_Q	0.739	0.93
250_H	400_Y	0.739	0.93
90_Q	304_Y	0.737	0.93
265_S	410_I	0.736	0.93
249_A	263_N	0.734	0.93
113_A	117_S	0.733	0.93
76_I	267_T	0.732	0.93
262_D	323_D	0.732	0.93
80_M	85_L	0.732	0.93
235_K	239_I	0.731	0.93
63_I	68_A	0.729	0.93
184_P	190_S	0.729	0.93
246_Y	316_S	0.724	0.93
324_M	400_Y	0.724	0.93
210_T	213_K	0.723	0.93
155_D	158_Y	0.722	0.92
244_I	316_S	0.721	0.92
218_K	221_A	0.719	0.92
350_S	353_T	0.719	0.92
298_L	371_S	0.718	0.92
45_A	413_E	0.716	0.92
348_W	351_S	0.712	0.92
52_I	56_S	0.711	0.92
293_A	296_L	0.710	0.92
401_H	405_D	0.710	0.92
344_S	348_W	0.710	0.92
277_L	426_V	0.709	0.92
294_E	323_D	0.709	0.92
146_G	170_A	0.708	0.92
354_A	357_K	0.707	0.92
152_S	176_Y	0.703	0.91
116_G	296_L	0.702	0.91
353_T	357_K	0.702	0.91
31_A	35_S	0.701	0.91
276_V	423_T	0.700	0.91
56_S	407_I	0.699	0.91
371_S	400_Y	0.699	0.91
60_G	68_A	0.698	0.91
386_F	422_V	0.697	0.91
321_N	372_D	0.696	0.91
180_E	203_K	0.694	0.91
234_K	277_L	0.694	0.91
178_N	203_K	0.693	0.91
429_A	432_K	0.692	0.91
141_T	168_A	0.691	0.91
77_A	230_I	0.689	0.91
227_S	293_A	0.687	0.91
428_E	432_K	0.686	0.90
324_M	371_S	0.686	0.90
237_K	281_P	0.686	0.90
260_A	405_D	0.685	0.90
102_L	217_L	0.684	0.90
201_I	206_G	0.684	0.90
62_R	264_G	0.684	0.90
116_G	120_T	0.682	0.90
312_E	316_S	0.681	0.90
299_L	303_H	0.681	0.90
120_T	123_Q	0.680	0.90
150_L	213_K	0.677	0.90
51_T	54_Q	0.676	0.90
348_W	352_R	0.676	0.90
356_E	360_F	0.675	0.90
145_K	169_G	0.675	0.90
239_I	243_D	0.672	0.90
355_A	359_G	0.671	0.89
277_L	282_S	0.671	0.89
137_Q	141_T	0.669	0.89
75_L	79_S	0.669	0.89
258_P	261_N	0.668	0.89
266_G	323_D	0.668	0.89
117_S	121_E	0.666	0.89
410_I	415_L	0.666	0.89
370_S	374_V	0.665	0.89
259_G	262_D	0.659	0.89
359_G	362_S	0.658	0.89
320_F	422_V	0.656	0.88
151_I	175_I	0.654	0.88
310_E	314_K	0.654	0.88
245_V	317_E	0.652	0.88
278_K	281_P	0.651	0.88
323_D	371_S	0.651	0.88
61_P	68_A	0.650	0.88
135_G	161_K	0.650	0.88
250_H	263_N	0.650	0.88
140_F	149_A	0.648	0.88
61_P	66_T	0.647	0.88
369_G	374_V	0.645	0.88
262_D	295_E	0.644	0.87
245_V	426_V	0.642	0.87
254_V	295_E	0.641	0.87
295_E	321_N	0.639	0.87
201_I	209_L	0.638	0.87
54_Q	82_K	0.637	0.87
408_E	412_K	0.637	0.87
33_Q	37_S	0.636	0.87
413_E	416_Q	0.635	0.87
184_P	193_K	0.634	0.87
54_Q	75_L	0.633	0.87
48_A	269_V	0.632	0.86
326_G	415_L	0.630	0.86
172_A	197_P	0.626	0.86
325_V	328_S	0.626	0.86
304_Y	308_L	0.626	0.86
85_L	278_K	0.626	0.86
47_H	51_T	0.625	0.86
321_N	401_H	0.624	0.86
69_E	228_Q	0.623	0.86
72_S	76_I	0.623	0.86
54_Q	59_I	0.623	0.86
333_S	336_Y	0.621	0.86
350_S	429_A	0.621	0.86
56_S	260_A	0.620	0.85
57_E	211_Q	0.618	0.85
372_D	401_H	0.617	0.85
274_A	278_K	0.615	0.85
38_E	41_L	0.612	0.85
289_I	304_Y	0.612	0.85
51_T	268_S	0.611	0.85
387_I	390_D	0.610	0.85
105_A	109_I	0.608	0.84
245_V	430_V	0.608	0.84
251_Y	267_T	0.606	0.84
423_T	427_Y	0.605	0.84
62_R	263_N	0.601	0.84
186_T	193_K	0.600	0.84
70_K	89_V	0.600	0.84
273_M	276_V	0.600	0.84
384_A	425_A	0.600	0.84
56_S	59_I	0.599	0.83
247_V	286_I	0.599	0.83
102_L	105_A	0.596	0.83
338_N	341_D	0.595	0.83
119_P	122_E	0.594	0.83
145_K	167_A	0.593	0.83
295_E	300_G	0.593	0.83
136_Y	140_F	0.592	0.83
64_A	227_S	0.588	0.82
41_L	45_A	0.587	0.82
69_E	227_S	0.585	0.82
33_Q	36_N	0.585	0.82
345_N	438_T	0.584	0.82
318_V	384_A	0.584	0.82
43_F	420_D	0.584	0.82
366_T	377_H	0.583	0.82
304_Y	311_K	0.583	0.82
166_E	196_I	0.583	0.82
302_S	378_E	0.582	0.82
375_P	378_E	0.581	0.82
231_I	310_E	0.581	0.82
317_E	435_K	0.580	0.81
107_R	212_Q	0.579	0.81
150_L	210_T	0.578	0.81
254_V	401_H	0.576	0.81
333_S	338_N	0.574	0.81
301_S	373_H	0.574	0.81
55_L	72_S	0.574	0.81
69_E	72_S	0.569	0.80
232_G	288_F	0.568	0.80
264_G	268_S	0.566	0.80
31_A	36_N	0.566	0.80
247_V	422_V	0.565	0.80
306_D	379_A	0.565	0.80
273_M	277_L	0.565	0.80
45_A	48_A	0.565	0.80
119_P	124_G	0.565	0.80
277_L	280_V	0.564	0.80
55_L	76_I	0.562	0.79
234_K	286_I	0.561	0.79
140_F	161_K	0.559	0.79
46_K	413_E	0.559	0.79
334_E	363_L	0.558	0.79
113_A	120_T	0.557	0.79
64_A	69_E	0.556	0.79
150_L	176_Y	0.556	0.79
34_I	38_E	0.555	0.79
132_A	135_G	0.553	0.78
357_K	424_A	0.552	0.78
92_F	307_H	0.552	0.78
62_R	72_S	0.551	0.78
165_A	196_I	0.551	0.78
372_D	400_Y	0.550	0.78
372_D	376_F	0.549	0.78
356_E	362_S	0.549	0.78
265_S	324_M	0.546	0.77
160_E	163_K	0.546	0.77
146_G	149_A	0.546	0.77
61_P	255_P	0.546	0.77
380_G	383_S	0.545	0.77
150_L	174_I	0.545	0.77
354_A	425_A	0.544	0.77
127_A	147_K	0.544	0.77
320_F	429_A	0.543	0.77
321_N	371_S	0.543	0.77
252_D	297_G	0.542	0.77
64_A	225_Q	0.542	0.77
323_D	401_H	0.541	0.77
295_E	372_D	0.541	0.77
197_P	217_L	0.539	0.77
294_E	372_D	0.538	0.76
301_S	321_N	0.538	0.76
332_A	338_N	0.538	0.76
59_I	74_L	0.538	0.76
138_K	160_E	0.536	0.76
114_A	118_A	0.536	0.76
107_R	110_L	0.535	0.76
43_F	419_G	0.535	0.76
340_L	343_Q	0.535	0.76
107_R	112_Q	0.535	0.76
54_Q	78_S	0.534	0.76
261_N	265_S	0.534	0.76
326_G	410_I	0.533	0.76
54_Q	79_S	0.532	0.76
123_Q	218_K	0.531	0.75
41_L	46_K	0.531	0.75
280_V	423_T	0.530	0.75
163_K	166_E	0.530	0.75
43_F	48_A	0.530	0.75
342_G	346_Y	0.529	0.75
245_V	318_V	0.528	0.75
53_S	57_E	0.527	0.75
344_S	347_V	0.527	0.75
334_E	339_T	0.526	0.75
367_Q	390_D	0.525	0.75
229_N	295_E	0.524	0.75
103_S	106_G	0.524	0.75
301_S	376_F	0.524	0.75
420_D	424_A	0.524	0.75
414_R	418_A	0.523	0.74
31_A	38_E	0.522	0.74
69_E	73_A	0.520	0.74
157_T	160_E	0.519	0.74
237_K	241_H	0.519	0.74
294_E	297_G	0.516	0.73
188_N	191_G	0.516	0.73
52_I	407_I	0.515	0.73
87_V	230_I	0.514	0.73
253_S	264_G	0.514	0.73
269_V	322_L	0.514	0.73
246_Y	287_R	0.513	0.73
62_R	253_S	0.512	0.73
246_Y	376_F	0.511	0.73
107_R	211_Q	0.510	0.73
176_Y	206_G	0.509	0.72
42_P	45_A	0.508	0.72
297_G	372_D	0.508	0.72
355_A	361_D	0.508	0.72
283_D	433_E	0.507	0.72
263_N	401_H	0.505	0.72
341_D	348_W	0.505	0.72
172_A	193_K	0.505	0.72
360_F	417_Q	0.504	0.72
90_Q	231_I	0.504	0.72
239_I	285_E	0.504	0.72
298_L	323_D	0.504	0.72
309_S	313_L	0.503	0.72
36_N	428_E	0.503	0.72
113_A	121_E	0.500	0.71
310_E	316_S	0.500	0.71
101_T	220_K	0.500	0.71

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4tweA	2	0.9275	100	0.323	Contact Map
2ek8A	2	0.8725	100	0.326	Contact Map
3fedA	2	0.9077	100	0.327	Contact Map
3kasA	2	0.9187	100	0.335	Contact Map
3iibA	2	0.8901	100	0.36	Contact Map
4r12A	1	0.7758	100	0.541	Contact Map
3k9tA	3	0.7758	100	0.577	Contact Map
1tkjA	1	0.5604	100	0.618	Contact Map
4mhpA	1	0.6066	100	0.631	Contact Map
3guxA	1	0.5231	100	0.631	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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