GREMLIN Database
YQXH - Uncharacterized protein YqxH
UniProt: P24811 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 140 (125)
Sequences: 715 (574)
Seq/√Len: 51.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
34_S67_F5.7741.00
44_K108_Q3.8411.00
56_A97_N2.7211.00
107_A124_I2.4461.00
73_A90_T2.4091.00
36_I68_F2.2171.00
53_S101_S2.1991.00
41_G101_S2.1691.00
47_K58_F2.1051.00
32_V75_V2.0911.00
25_K87_T2.0801.00
33_L95_I1.9821.00
115_S119_D1.8570.99
99_G121_L1.8530.99
37_D41_G1.8030.99
59_G101_S1.7400.99
63_K98_E1.7400.99
48_F108_Q1.7050.99
37_D101_S1.6820.98
66_N94_Y1.6710.98
60_Y97_N1.6480.98
41_G53_S1.6170.98
119_D126_N1.6140.98
107_A113_I1.6060.98
42_V100_L1.5740.98
41_G59_G1.4750.96
30_L70_V1.4360.96
65_L106_L1.4350.96
49_K123_T1.4340.96
47_K110_G1.3630.95
99_G123_T1.3570.94
101_S104_E1.3560.94
107_A121_L1.3380.94
51_L100_L1.2960.93
102_I109_I1.2950.93
53_S59_G1.2770.92
7_F11_E1.2630.92
37_D59_G1.2500.92
106_L111_V1.2470.91
26_Y91_V1.2380.91
64_L69_A1.2360.91
11_E18_V1.2300.91
37_D53_S1.2020.90
64_L71_I1.1800.89
47_K109_I1.1700.89
56_A60_Y1.1680.88
53_S104_E1.1630.88
60_Y71_I1.1630.88
12_T15_L1.1500.88
70_V91_V1.1470.88
46_W120_R1.1330.87
41_G104_E1.1290.87
29_L79_V1.1240.87
37_D104_E1.1200.86
13_L126_N1.1100.86
85_V125_E1.0630.83
12_T19_Y1.0600.83
118_T122_Q1.0500.82
29_L75_V1.0440.82
28_D32_V1.0370.82
45_A49_K1.0320.81
52_R122_Q1.0260.81
20_L71_I1.0220.81
29_L95_I1.0180.80
31_L68_F1.0170.80
33_L76_I1.0020.79
81_N99_G0.9760.78
40_T105_N0.9710.77
93_F112_K0.9620.77
45_A59_G0.9580.76
18_V92_L0.9360.75
113_I118_T0.9350.75
36_I102_I0.9100.72
59_G104_E0.9080.72
38_V44_K0.8980.71
9_N12_T0.8930.71
79_V95_I0.8900.71
13_L20_L0.8850.70
59_G105_N0.8850.70
69_A90_T0.8850.70
96_A99_G0.8840.70
74_N91_V0.8800.70
16_A19_Y0.8770.70
38_V58_F0.8710.69
115_S130_Q0.8700.69
39_L43_I0.8500.67
103_T113_I0.8460.67
10_F126_N0.8380.66
101_S105_N0.8380.66
57_W62_R0.8280.65
103_T117_I0.8140.64
38_V55_S0.8060.63
57_W66_N0.7990.62
58_F62_R0.7980.62
65_L125_E0.7920.62
51_L56_A0.7880.61
8_I12_T0.7870.61
60_Y64_L0.7830.61
11_E92_L0.7760.60
15_L18_V0.7710.60
69_A94_Y0.7630.59
113_I131_S0.7560.58
115_S118_T0.7520.58
103_T121_L0.7480.57
46_W49_K0.7480.57
45_A104_E0.7470.57
30_L100_L0.7470.57
62_R72_L0.7450.57
14_D18_V0.7420.57
43_I61_V0.7420.57
26_Y86_L0.7400.57
23_G87_T0.7400.57
8_I13_L0.7340.56
63_K77_D0.7330.56
29_L33_L0.7320.56
38_V97_N0.7220.55
89_G92_L0.7180.54
76_I99_G0.7160.54
33_L99_G0.7130.54
95_I99_G0.7070.53
12_T27_L0.7040.53
112_K118_T0.7030.53
70_V129_E0.7020.53
64_L70_V0.6960.52
52_R62_R0.6940.52
14_D56_A0.6930.52
42_V46_W0.6920.52
33_L72_L0.6850.51
77_D98_E0.6850.51
38_V56_A0.6810.50
65_L109_I0.6810.50
21_F87_T0.6770.50
19_Y28_D0.6770.50
92_L96_A0.6760.50
62_R65_L0.6750.50
58_F106_L0.6730.50
38_V42_V0.6650.49
17_R21_F0.6650.49
27_L31_L0.6600.48
18_V21_F0.6570.48
106_L113_I0.6540.48
62_R66_N0.6440.47
37_D105_N0.6430.46
47_K61_V0.6390.46
34_S54_R0.6390.46
34_S40_T0.6360.46
35_I67_F0.6340.46
48_F115_S0.6310.45
9_N19_Y0.6290.45
69_A106_L0.6240.45
40_T55_S0.6120.43
44_K48_F0.6100.43
26_Y92_L0.6070.43
24_V28_D0.6030.42
44_K95_I0.6010.42
27_L119_D0.5990.42
116_S128_K0.5970.42
47_K112_K0.5790.40
27_L61_V0.5760.40
64_L76_I0.5710.39
72_L99_G0.5650.39
72_L85_V0.5630.38
53_S105_N0.5610.38
42_V73_A0.5570.38
19_Y61_V0.5530.37
20_L32_V0.5510.37
8_I68_F0.5450.37
38_V87_T0.5400.36
44_K60_Y0.5390.36
54_R122_Q0.5370.36
56_A105_N0.5360.36
84_G88_F0.5340.36
7_F60_Y0.5330.35
8_I117_I0.5320.35
95_I102_I0.5320.35
41_G105_N0.5310.35
52_R60_Y0.5300.35
50_K122_Q0.5270.35
45_A101_S0.5220.34
31_L78_T0.5220.34
12_T16_A0.5210.34
12_T48_F0.5210.34
80_L84_G0.5150.34
115_S129_E0.5120.33
44_K61_V0.5080.33
57_W91_V0.5030.33
57_W97_N0.5010.32
94_Y106_L0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2htjA 1 0.3857 4.4 0.951 Contact Map
2i88A 1 0.3643 3.8 0.953 Contact Map
4qicB 2 0.3214 3.8 0.953 Contact Map
2kv5A 1 0.2357 3.8 0.953 Contact Map
4wzxA 1 0.2857 3.7 0.953 Contact Map
2olsA 2 0.4429 3.4 0.954 Contact Map
3bo0B 1 0.2643 3.3 0.954 Contact Map
4je3A 1 0.4 3 0.955 Contact Map
2z5iI 2 0.1929 3 0.955 Contact Map
2kpoA 1 0.3714 2.9 0.956 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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