GREMLIN Database
FLGB - Flagellar basal body rod protein FlgB
UniProt: P24500 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 129 (121)
Sequences: 1683 (1294)
Seq/√Len: 117.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
24_V42_V2.9901.00
29_I93_V2.9581.00
60_T64_H2.8751.00
47_L50_Q2.7891.00
57_A67_F2.7361.00
116_G120_S2.7001.00
47_L51_E2.6481.00
43_S46_N2.6191.00
18_A103_N2.6111.00
8_I118_F2.5561.00
37_Y40_K2.5041.00
99_E102_Q2.4931.00
102_Q106_N2.4911.00
13_N16_S2.2951.00
20_I23_K2.2591.00
39_A90_N2.2411.00
59_K66_D2.2211.00
17_R42_V2.2051.00
27_N37_Y2.0331.00
59_K65_V2.0061.00
121_L125_L1.9381.00
24_V76_I1.8271.00
25_I100_L1.7881.00
21_K41_K1.7811.00
11_L110_L1.7231.00
119_N122_K1.6181.00
22_Q103_N1.5541.00
20_I42_V1.5211.00
112_E116_G1.4131.00
123_T126_T1.3991.00
12_E16_S1.3081.00
45_Q49_D1.3081.00
25_I41_K1.2991.00
107_Y111_V1.2760.99
39_A79_S1.2650.99
95_K99_E1.2370.99
92_D95_K1.2230.99
117_K120_S1.2190.99
27_N111_V1.1970.99
93_V97_M1.1950.99
97_M101_A1.1920.99
57_A64_H1.1900.99
61_D64_H1.1870.99
108_Q111_V1.1750.99
25_I103_N1.1710.99
40_K78_A1.1620.99
33_D83_S1.1570.99
122_K126_T1.1410.99
111_V115_N1.1150.99
15_L19_D1.0940.98
7_T12_E1.0910.98
94_D97_M1.0550.98
43_S77_V1.0250.98
17_R24_V1.0140.97
27_N40_K0.9970.97
23_K26_T0.9750.97
9_Q22_Q0.9710.97
113_R120_S0.9530.96
22_Q94_D0.9530.96
15_L111_V0.9500.96
8_I117_K0.9500.96
14_A109_A0.9360.96
16_S19_D0.9300.96
95_K98_T0.9120.95
21_K99_E0.8980.95
42_V77_V0.8960.95
112_E115_N0.8820.94
52_S55_L0.8820.94
114_M117_K0.8460.93
53_S56_E0.8350.92
11_L113_R0.8290.92
10_N48_L0.8290.92
59_K64_H0.8280.92
110_L114_M0.8250.92
98_T101_A0.8200.92
11_L117_K0.8110.91
24_V37_Y0.8000.91
86_Q98_T0.7990.91
109_A113_R0.7940.90
64_H97_M0.7830.90
82_T95_K0.7770.90
112_E118_F0.7760.89
21_K95_K0.7730.89
57_A65_V0.7690.89
29_I32_I0.7680.89
18_A106_N0.7680.89
23_K108_Q0.7650.89
12_E93_V0.7600.88
14_A106_N0.7510.88
108_Q115_N0.7500.88
22_Q100_L0.7430.87
44_F48_L0.7420.87
82_T90_N0.7310.86
47_L75_S0.7290.86
58_I105_I0.7270.86
81_D92_D0.7210.86
65_V69_D0.7210.86
118_F125_L0.7190.86
41_K46_N0.7020.84
41_K111_V0.6980.84
104_Q108_Q0.6960.84
17_R90_N0.6920.83
50_Q53_S0.6910.83
84_Y92_D0.6900.83
87_N104_Q0.6800.82
18_A27_N0.6730.82
108_Q122_K0.6720.82
8_I35_P0.6690.81
94_D105_I0.6690.81
62_Y70_T0.6660.81
26_T113_R0.6660.81
97_M100_L0.6650.81
17_R21_K0.6630.81
53_S63_R0.6620.81
113_R117_K0.6580.80
20_I74_Y0.6550.80
39_A96_E0.6530.80
46_N70_T0.6510.79
9_Q12_E0.6490.79
53_S71_D0.6490.79
60_T65_V0.6460.79
53_S66_D0.6450.79
10_N93_V0.6450.79
52_S56_E0.6430.79
109_A116_G0.6420.78
115_N119_N0.6410.78
52_S73_N0.6360.78
84_Y95_K0.6350.78
56_E66_D0.6330.78
14_A17_R0.6320.77
118_F121_L0.6300.77
32_I69_D0.6280.77
86_Q126_T0.6250.77
41_K79_S0.6200.76
46_N49_D0.6190.76
41_K77_V0.6180.76
82_T92_D0.6150.75
29_I102_Q0.6130.75
40_K79_S0.6000.74
54_R71_D0.5980.73
56_E70_T0.5970.73
12_E33_D0.5940.73
119_N123_T0.5900.72
45_Q59_K0.5890.72
24_V40_K0.5870.72
18_A92_D0.5840.72
108_Q112_E0.5830.72
73_N80_G0.5820.71
70_T73_N0.5820.71
56_E69_D0.5810.71
98_T120_S0.5750.71
79_S90_N0.5750.71
54_R62_Y0.5730.70
13_N105_I0.5700.70
13_N45_Q0.5690.70
108_Q116_G0.5660.69
23_K125_L0.5650.69
66_D70_T0.5650.69
13_N77_V0.5600.69
62_Y66_D0.5560.68
8_I12_E0.5530.68
43_S47_L0.5520.67
113_R116_G0.5520.67
63_R69_D0.5510.67
42_V71_D0.5470.67
38_K118_F0.5430.66
103_N112_E0.5390.66
45_Q106_N0.5380.65
46_N50_Q0.5360.65
114_M118_F0.5330.65
25_I81_D0.5330.65
30_A81_D0.5270.64
101_A104_Q0.5250.64
97_M113_R0.5250.64
49_D56_E0.5240.63
92_D96_E0.5240.63
78_A81_D0.5230.63
75_S79_S0.5180.63
87_N90_N0.5120.62
116_G119_N0.5080.61
58_I87_N0.5030.60
16_S118_F0.5000.60
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3a69A 3 0.4806 98.7 0.753 Contact Map
4ut1A 1 0.2171 98.2 0.785 Contact Map
4ea3A 2 0.2868 9.4 0.94 Contact Map
3tr9A 3 0.8062 4.8 0.948 Contact Map
3kx6A 4 0.8605 4.4 0.949 Contact Map
1oryB 2 0.3101 4.1 0.95 Contact Map
2d4yA 1 0.6357 4 0.95 Contact Map
2y5sA 2 0.7829 3.9 0.95 Contact Map
4d2jA 4 0.8605 3.8 0.951 Contact Map
3buxB 1 0.6589 3.7 0.951 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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