GREMLIN Database
RECR - Recombination protein RecR
UniProt: P24277 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 198 (192)
Sequences: 2898 (1607)
Seq/√Len: 116.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
79_K103_Q4.6531.00
58_S67_D4.5041.00
80_S137_T3.5361.00
49_N53_N3.3541.00
20_I28_L3.3181.00
123_K126_E3.2171.00
131_L160_L2.7341.00
139_V160_L2.6741.00
45_K48_V2.6341.00
174_L183_A2.6101.00
143_T153_A2.6041.00
58_S68_P2.5971.00
14_F43_F2.5691.00
82_I136_V2.5481.00
112_S115_D2.5151.00
24_T28_L2.4051.00
14_F29_A2.3991.00
40_V47_L2.3821.00
14_F32_V2.3221.00
61_G126_E2.3131.00
37_E52_R2.2561.00
59_V68_P2.2411.00
55_T67_D2.1991.00
45_K49_N2.0431.00
61_G123_K2.0341.00
41_L52_R1.8831.00
78_D81_V1.8101.00
66_Q73_E1.7941.00
41_L48_V1.7851.00
40_V51_K1.7731.00
129_K132_Q1.7611.00
118_G121_D1.7491.00
124_I156_I1.7151.00
37_E41_L1.6781.00
124_I128_L1.6701.00
44_A48_V1.6231.00
62_H91_V1.5911.00
36_K39_V1.5881.00
78_D137_T1.5481.00
105_H130_R1.5381.00
96_K185_E1.5321.00
168_S195_R1.4751.00
9_K49_N1.4671.00
132_Q163_S1.4471.00
129_K133_D1.4131.00
56_Y108_H1.4121.00
110_A144_N1.3741.00
140_I192_L1.3671.00
86_Q110_A1.3491.00
8_S12_D1.3461.00
108_H123_K1.3241.00
190_K193_E1.3231.00
6_P65_D1.3191.00
110_A146_N1.3121.00
41_L45_K1.3061.00
95_E104_Y1.2720.99
59_V134_D1.2630.99
125_P129_K1.2610.99
94_M192_L1.2290.99
122_I156_I1.2280.99
172_H190_K1.2150.99
7_I54_L1.1970.99
13_S16_K1.1910.99
175_P178_G1.1880.99
10_L50_A1.1780.99
13_S42_D1.1700.99
59_V133_D1.1640.99
71_I91_V1.1440.99
54_L63_I1.1370.99
100_Y103_Q1.1340.99
64_T68_P1.1330.99
11_I26_V1.1250.99
16_K39_V1.1080.98
9_K42_D1.0990.98
97_M189_S1.0960.98
48_V52_R1.0940.98
32_V35_M1.0920.98
128_L159_L1.0840.98
131_L135_Q1.0840.98
159_L162_P1.0760.98
60_C72_C1.0380.98
37_E51_K1.0370.98
143_T169_R1.0360.98
160_L167_L1.0350.98
91_V106_V1.0320.98
40_V43_F1.0290.98
79_K135_Q1.0260.97
74_D101_N1.0220.97
184_D187_T1.0220.97
22_P178_G1.0200.97
5_E9_K1.0070.97
34_G87_D0.9930.97
80_S133_D0.9790.97
110_A143_T0.9710.97
62_H88_P0.9690.96
59_V79_K0.9670.96
38_D41_L0.9660.96
141_L167_L0.9580.96
59_V130_R0.9420.96
131_L165_I0.9390.96
83_C102_G0.9350.96
13_S46_A0.9200.95
81_V137_T0.9190.95
88_P108_H0.9180.95
30_F194_G0.9170.95
150_E154_M0.9120.95
88_P91_V0.9080.95
59_V105_H0.8990.95
30_F92_I0.8930.94
128_L132_Q0.8910.94
53_N65_D0.8880.94
39_V42_D0.8840.94
17_L28_L0.8620.93
11_I140_I0.8600.93
69_C72_C0.8540.93
55_T64_T0.8530.93
6_P46_A0.8480.93
7_I29_A0.8480.93
90_D178_G0.8450.93
60_C69_C0.8450.93
66_Q70_Y0.8410.92
71_I77_R0.8370.92
131_L156_I0.8350.92
83_C100_Y0.8350.92
6_P53_N0.8320.92
68_P73_E0.8170.91
55_T58_S0.8160.91
190_K194_G0.8130.91
124_I159_L0.8060.91
29_A50_A0.8010.91
119_P155_Y0.7980.90
82_I133_D0.7930.90
35_M39_V0.7890.90
119_P122_I0.7850.90
111_I147_I0.7820.89
103_Q130_R0.7680.89
75_T79_K0.7660.88
45_K73_E0.7640.88
13_S39_V0.7640.88
179_D182_Y0.7630.88
20_I25_A0.7630.88
30_F88_P0.7620.88
41_L44_A0.7610.88
128_L160_L0.7610.88
61_G108_H0.7600.88
175_P187_T0.7590.88
22_P174_L0.7550.88
111_I151_A0.7500.87
97_M192_L0.7490.87
147_I172_H0.7480.87
141_L153_A0.7450.87
6_P49_N0.7440.87
79_K134_D0.7390.87
40_V44_A0.7350.86
55_T68_P0.7300.86
105_H122_I0.7280.86
41_L51_K0.7260.86
105_H126_E0.7250.86
6_P54_L0.7180.85
154_M186_V0.7150.85
128_L131_L0.7110.84
132_Q162_P0.7110.84
132_Q135_Q0.7060.84
61_G172_H0.7030.84
81_V100_Y0.7020.84
76_R101_N0.7020.84
89_K111_I0.7020.84
78_D103_Q0.6950.83
138_E195_R0.6950.83
110_A117_I0.6940.83
83_C94_M0.6920.83
23_K196_R0.6920.83
8_S22_P0.6910.83
15_M22_P0.6900.83
169_R172_H0.6810.82
34_G114_M0.6770.81
59_V126_E0.6750.81
142_A170_I0.6730.81
26_V191_A0.6710.81
14_F20_I0.6700.81
155_Y159_L0.6660.80
90_D110_A0.6640.80
109_G152_T0.6630.80
30_F63_I0.6620.80
82_I103_Q0.6610.80
78_D101_N0.6600.80
150_E190_K0.6540.79
99_E192_L0.6520.79
109_G122_I0.6520.79
73_E133_D0.6500.79
13_S43_F0.6500.79
77_R95_E0.6470.79
70_Y165_I0.6470.79
81_V166_K0.6470.79
120_E125_P0.6430.78
125_P159_L0.6420.78
43_F175_P0.6390.78
178_G187_T0.6390.78
33_L50_A0.6330.77
91_V145_P0.6330.77
183_A194_G0.6290.77
126_E129_K0.6260.76
61_G179_D0.6250.76
137_T166_K0.6150.75
129_K161_K0.6120.75
171_A195_R0.6110.74
91_V189_S0.6060.74
21_G25_A0.6060.74
170_I182_Y0.6050.74
117_I121_D0.6040.74
12_D42_D0.5920.72
177_G195_R0.5910.72
175_P184_D0.5910.72
26_V181_E0.5900.72
96_K105_H0.5890.72
105_H155_Y0.5870.72
73_E84_V0.5870.72
70_Y101_N0.5860.71
23_K179_D0.5810.71
99_E193_E0.5790.70
113_P118_G0.5790.70
164_G167_L0.5780.70
21_G27_R0.5780.70
82_I105_H0.5750.70
81_V101_N0.5740.70
87_D93_A0.5740.70
136_V139_V0.5730.70
17_L21_G0.5720.70
90_D93_A0.5700.69
42_D45_K0.5670.69
99_E190_K0.5660.69
5_E8_S0.5660.69
91_V94_M0.5650.69
83_C192_L0.5650.69
144_N172_H0.5650.69
46_A49_N0.5650.69
59_V62_H0.5650.69
5_E70_Y0.5650.69
110_A170_I0.5610.68
7_I13_S0.5600.68
35_M40_V0.5560.67
185_E188_L0.5550.67
154_M158_R0.5540.67
18_P25_A0.5530.67
131_L163_S0.5520.67
34_G89_K0.5520.67
118_G151_A0.5490.66
7_I114_M0.5480.66
109_G130_R0.5450.66
116_G146_N0.5450.66
18_P21_G0.5430.66
31_F35_M0.5430.66
11_I30_F0.5410.65
71_I188_L0.5410.65
108_H143_T0.5410.65
36_K159_L0.5410.65
14_F33_L0.5400.65
87_D91_V0.5380.65
83_C142_A0.5370.65
128_L156_I0.5350.64
55_T66_Q0.5340.64
23_K178_G0.5330.64
176_V196_R0.5280.63
160_L186_V0.5270.63
10_L191_A0.5270.63
92_I172_H0.5220.63
145_P188_L0.5210.62
10_L14_F0.5180.62
168_S171_A0.5180.62
30_F108_H0.5170.62
12_D15_M0.5170.62
100_Y140_I0.5160.62
157_S161_K0.5150.62
79_K166_K0.5140.61
90_D179_D0.5140.61
153_A169_R0.5110.61
172_H176_V0.5100.61
82_I142_A0.5100.61
143_T149_G0.5090.61
175_P183_A0.5070.60
80_S103_Q0.5060.60
75_T103_Q0.5060.60
154_M194_G0.5060.60
7_I67_D0.5040.60
56_Y61_G0.5020.60
49_N52_R0.5010.59
13_S94_M0.5010.59
120_E193_E0.5000.59
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3vdpA 2 1 100 0.051 Contact Map
1vddA 7 0.9899 100 0.066 Contact Map
1mw9X 1 0.5455 97.2 0.899 Contact Map
2gaiA 1 0.5253 97.1 0.9 Contact Map
4dduA 1 0.8737 96.3 0.909 Contact Map
4cgyA 1 0.6162 96.2 0.91 Contact Map
1i7dA 1 0.697 95.9 0.913 Contact Map
1gkuB 1 0.8232 95.7 0.914 Contact Map
2fcjA 2 0.5404 94.2 0.921 Contact Map
2owoA 1 0.2727 87.3 0.934 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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