OPPA - BACSU - GREMLIN Contacts

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OPPA - Oligopeptide-binding protein OppA

UniProt:	P24141	Sequences: MKKRWSIVTLMLIFTLVLSACGFGGTGSNGEGKKDSKGKTTLNINIKTEPFSLHPGLANDSVSGGVIRQTFEGLTRINADGEPEEGMASKIETSKDGKTYTFTIRDGVKWSNGDPVTAQDFEYAWKWALDPNNESQYAYQLYYIKGAEAANTGKGSLDDVAVKAVNDKTLKVELNNPTPYFTELTAFYTYMPINEKIAEKNKKWNTNAGDDYVSNGPFKMTAWKHSGSITLEKNDQYWDKDKVKLKKIDMVMINNNNTELKKFQAGELDWAGMPLGQLPTESLPTLKKDGSLHVEPIAGVYWYKFNTEAKPLDNVNIRKALTYSLDRQSIVKNVTQGEQMPAMAAVPPTMKGFEDNKEGYFKDNDVKTAKEYLEKGLKEMGLSKASDLPKIKLSYNTDDAHAKIAQAVQEMWKKNLGVDVELDNSEWNVYIDKLHSQDYQIGRMGWLGDFNDPINFLELFRDKNGGNNDTGWENPEFKKLLNQSQTETDKTKRAELLKKAEGIFIDEMPVAPIYFYTDTWVQDENLKGVIMPGTGEVYFRNAYFK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	545 (487)
Sequences:	23065 (17561)
Seq/√Len:	795.8

ECOLI - YGIS MPPA OPPA SAPA GSIB DDPA DPPA NIKA YEJA YBAE SGRR
BACSU - OPPA DPPE APPA YHJP
HALSA - Q9HMW4 Q9HMI3
SULSO - Q97VK5 Q97UG7 Q97VF7 Q97UH5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
221_T	232_E	4.075	1.00
316_N	375_K	3.325	1.00
163_K	171_K	3.258	1.00
165_V	171_K	3.227	1.00
368_T	371_E	3.129	1.00
166_N	169_T	3.017	1.00
106_D	168_K	3.012	1.00
328_Q	332_K	2.989	1.00
122_E	126_K	2.913	1.00
479_K	483_Q	2.841	1.00
487_E	492_K	2.775	1.00
219_K	232_E	2.756	1.00
122_E	164_A	2.657	1.00
310_K	313_D	2.562	1.00
321_L	412_W	2.492	1.00
371_E	375_K	2.489	1.00
323_Y	368_T	2.472	1.00
326_D	329_S	2.470	1.00
472_W	507_E	2.385	1.00
195_E	199_E	2.382	1.00
90_K	103_T	2.381	1.00
116_V	215_N	2.372	1.00
92_E	103_T	2.358	1.00
119_Q	164_A	2.355	1.00
476_E	479_K	2.333	1.00
94_S	98_K	2.299	1.00
78_N	82_E	2.292	1.00
41_T	247_K	2.277	1.00
75_T	91_I	2.245	1.00
163_K	173_E	2.231	1.00
390_K	419_D	2.229	1.00
99_T	171_K	2.198	1.00
315_V	319_K	2.165	1.00
316_N	372_Y	2.164	1.00
316_N	319_K	2.163	1.00
392_K	421_E	2.154	1.00
463_K	473_E	2.146	1.00
413_K	419_D	2.137	1.00
111_S	234_N	2.135	1.00
114_D	196_K	2.127	1.00
101_T	171_K	2.127	1.00
78_N	84_E	2.104	1.00
109_K	115_P	2.101	1.00
492_K	495_E	2.089	1.00
474_N	503_I	2.061	1.00
108_V	116_V	2.038	1.00
230_T	247_K	2.004	1.00
145_K	175_N	1.987	1.00
463_K	478_K	1.986	1.00
109_K	236_Q	1.975	1.00
72_E	86_G	1.968	1.00
489_D	492_K	1.965	1.00
99_T	173_E	1.964	1.00
474_N	507_E	1.958	1.00
483_Q	496_L	1.956	1.00
309_A	440_Q	1.941	1.00
93_T	100_Y	1.936	1.00
41_T	249_D	1.908	1.00
119_Q	195_E	1.896	1.00
495_E	499_K	1.885	1.00
120_D	195_E	1.879	1.00
103_T	169_T	1.873	1.00
54_H	127_W	1.864	1.00
262_K	267_E	1.862	1.00
125_W	172_V	1.851	1.00
117_T	120_D	1.834	1.00
476_E	499_K	1.823	1.00
89_S	106_D	1.820	1.00
121_F	170_L	1.817	1.00
45_N	268_L	1.815	1.00
219_K	235_D	1.806	1.00
224_K	227_G	1.788	1.00
145_K	173_E	1.785	1.00
409_Q	413_K	1.781	1.00
477_F	500_A	1.774	1.00
484_S	497_L	1.758	1.00
305_F	511_A	1.755	1.00
342_A	515_F	1.728	1.00
222_A	230_T	1.725	1.00
222_A	228_S	1.712	1.00
232_E	247_K	1.696	1.00
433_K	438_D	1.684	1.00
315_V	507_E	1.681	1.00
112_N	194_N	1.666	1.00
480_L	499_K	1.663	1.00
43_N	249_D	1.663	1.00
502_G	506_D	1.660	1.00
324_S	416_L	1.655	1.00
107_G	115_P	1.652	1.00
89_S	103_T	1.644	1.00
40_T	246_K	1.640	1.00
145_K	161_A	1.638	1.00
319_K	368_T	1.637	1.00
484_S	496_L	1.634	1.00
114_D	194_N	1.609	1.00
394_S	423_D	1.606	1.00
119_Q	167_D	1.603	1.00
476_E	503_I	1.593	1.00
161_A	173_E	1.588	1.00
119_Q	122_E	1.587	1.00
221_T	247_K	1.586	1.00
284_P	287_K	1.583	1.00
233_K	246_K	1.582	1.00
475_P	479_K	1.575	1.00
305_F	441_I	1.562	1.00
228_S	249_D	1.556	1.00
75_T	102_F	1.550	1.00
392_K	419_D	1.541	1.00
94_S	99_T	1.535	1.00
365_D	368_T	1.532	1.00
426_E	429_V	1.530	1.00
118_A	164_A	1.515	1.00
499_K	502_G	1.515	1.00
480_L	496_L	1.512	1.00
89_S	105_R	1.506	1.00
224_K	228_S	1.499	1.00
264_Q	285_T	1.494	1.00
328_Q	341_P	1.491	1.00
117_T	167_D	1.478	1.00
325_L	408_V	1.473	1.00
218_F	245_L	1.468	1.00
91_I	102_F	1.455	1.00
473_E	478_K	1.447	1.00
432_D	436_S	1.445	1.00
253_I	262_K	1.438	1.00
402_A	406_Q	1.431	1.00
319_K	508_M	1.429	1.00
322_T	508_M	1.429	1.00
487_E	496_L	1.419	1.00
60_D	63_S	1.405	1.00
72_E	238_W	1.396	1.00
370_K	374_E	1.392	1.00
496_L	499_K	1.392	1.00
483_Q	492_K	1.389	1.00
101_T	169_T	1.385	1.00
291_S	524_E	1.358	1.00
315_V	506_D	1.356	1.00
308_E	471_G	1.355	1.00
72_E	215_N	1.345	1.00
494_A	498_K	1.344	1.00
452_D	493_R	1.342	1.00
367_K	370_K	1.340	1.00
230_T	249_D	1.335	1.00
321_L	418_V	1.334	1.00
109_K	234_N	1.334	1.00
390_K	421_E	1.316	1.00
503_I	507_E	1.312	1.00
312_L	321_L	1.309	1.00
108_V	215_N	1.307	1.00
317_I	373_L	1.306	1.00
165_V	169_T	1.305	1.00
423_D	433_K	1.305	1.00
111_S	219_K	1.305	1.00
115_P	168_K	1.295	1.00
495_E	498_K	1.293	1.00
331_V	341_P	1.292	1.00
103_T	168_K	1.288	1.00
164_A	167_D	1.283	1.00
411_M	415_N	1.272	1.00
492_K	496_L	1.270	1.00
43_N	251_V	1.268	1.00
194_N	197_I	1.268	1.00
172_V	181_F	1.267	1.00
122_E	162_V	1.264	1.00
112_N	196_K	1.261	1.00
479_K	482_N	1.259	1.00
262_K	268_L	1.249	1.00
43_N	269_D	1.244	1.00
208_A	212_Y	1.236	1.00
483_Q	487_E	1.234	1.00
45_N	259_E	1.225	1.00
309_A	313_D	1.225	1.00
480_L	503_I	1.222	1.00
116_V	192_P	1.220	1.00
221_T	230_T	1.220	1.00
372_Y	375_K	1.212	1.00
462_D	482_N	1.209	1.00
462_D	478_K	1.205	1.00
42_L	270_W	1.198	1.00
100_Y	181_F	1.193	1.00
407_A	411_M	1.193	1.00
39_K	246_K	1.191	1.00
354_E	357_K	1.185	1.00
348_P	515_F	1.179	1.00
263_F	521_V	1.178	1.00
331_V	339_Q	1.177	1.00
124_A	192_P	1.174	1.00
371_E	374_E	1.174	1.00
85_E	91_I	1.172	1.00
105_R	108_V	1.170	1.00
394_S	421_E	1.169	1.00
231_L	250_M	1.167	1.00
239_D	242_K	1.162	1.00
476_E	480_L	1.159	1.00
87_M	215_N	1.159	1.00
304_K	442_G	1.154	1.00
111_S	236_Q	1.151	1.00
374_E	379_E	1.145	1.00
269_D	525_N	1.143	1.00
176_N	486_T	1.142	1.00
126_K	130_D	1.141	1.00
105_R	238_W	1.131	1.00
472_W	477_F	1.131	1.00
228_S	251_V	1.129	1.00
409_Q	422_L	1.124	1.00
76_R	84_E	1.124	1.00
121_F	192_P	1.123	1.00
269_D	523_D	1.115	1.00
21_C	24_G	1.115	1.00
412_W	420_V	1.110	1.00
366_V	370_K	1.109	1.00
491_T	494_A	1.108	1.00
335_T	514_Y	1.105	1.00
427_W	431_I	1.101	1.00
329_S	411_M	1.100	1.00
293_H	524_E	1.100	1.00
92_E	101_T	1.097	1.00
324_S	412_W	1.096	1.00
264_Q	289_D	1.093	1.00
13_I	16_L	1.092	1.00
437_Q	471_G	1.083	1.00
118_A	165_V	1.082	1.00
233_K	243_V	1.081	1.00
162_V	170_L	1.080	1.00
219_K	234_N	1.078	1.00
319_K	372_Y	1.075	1.00
366_V	416_L	1.074	1.00
284_P	288_K	1.073	1.00
76_R	86_G	1.071	1.00
94_S	101_T	1.068	1.00
14_F	17_V	1.067	1.00
21_C	25_G	1.066	1.00
96_D	99_T	1.064	1.00
66_V	231_L	1.063	1.00
143_Y	178_T	1.061	1.00
483_Q	499_K	1.060	1.00
317_I	376_G	1.050	1.00
315_V	508_M	1.046	1.00
102_F	172_V	1.043	1.00
123_Y	195_E	1.041	1.00
462_D	473_E	1.040	1.00
293_H	522_Q	1.032	1.00
89_S	168_K	1.031	1.00
115_P	167_D	1.028	1.00
197_I	213_V	1.027	1.00
120_D	123_Y	1.024	1.00
393_L	420_V	1.023	1.00
491_T	495_E	1.022	1.00
503_I	506_D	1.022	1.00
100_Y	182_T	1.020	1.00
111_S	213_V	1.020	1.00
258_T	262_K	1.019	1.00
196_K	200_K	1.016	1.00
409_Q	420_V	1.011	1.00
87_M	108_V	1.010	1.00
316_N	376_G	1.007	1.00
322_T	327_R	1.005	1.00
480_L	500_A	1.004	1.00
480_L	483_Q	1.000	1.00
103_T	106_D	0.999	1.00
42_L	245_L	0.993	1.00
232_E	235_D	0.993	1.00
408_V	412_W	0.982	1.00
392_K	423_D	0.981	1.00
367_K	371_E	0.981	1.00
335_T	339_Q	0.978	1.00
305_F	321_L	0.977	1.00
454_I	485_Q	0.975	1.00
110_W	120_D	0.971	1.00
94_S	97_G	0.970	1.00
340_M	517_T	0.968	1.00
42_L	526_L	0.967	1.00
472_W	509_P	0.965	1.00
126_K	129_L	0.964	1.00
233_K	242_K	0.962	1.00
366_V	415_N	0.961	1.00
118_A	170_L	0.959	1.00
123_Y	198_A	0.959	1.00
410_E	413_K	0.958	1.00
283_L	287_K	0.957	1.00
477_F	504_F	0.955	1.00
268_L	271_A	0.954	1.00
368_T	372_Y	0.948	1.00
98_K	145_K	0.947	1.00
354_E	498_K	0.946	1.00
332_K	337_G	0.945	1.00
100_Y	174_L	0.945	1.00
405_A	422_L	0.945	1.00
484_S	500_A	0.944	1.00
330_I	404_I	0.942	1.00
111_S	214_S	0.941	1.00
103_T	166_N	0.939	1.00
178_T	184_L	0.939	1.00
75_T	182_T	0.938	1.00
282_S	285_T	0.937	1.00
87_M	121_F	0.937	1.00
101_T	165_V	0.933	1.00
106_D	115_P	0.930	1.00
174_L	181_F	0.930	1.00
477_F	481_L	0.925	1.00
482_N	486_T	0.922	1.00
49_E	223_W	0.921	1.00
73_G	86_G	0.919	1.00
18_L	21_C	0.918	1.00
261_K	264_Q	0.918	1.00
111_S	220_M	0.909	1.00
75_T	88_A	0.907	1.00
410_E	415_N	0.905	1.00
331_V	514_Y	0.902	1.00
72_E	237_Y	0.896	1.00
364_N	415_N	0.895	1.00
322_T	511_A	0.894	1.00
319_K	506_D	0.893	1.00
70_T	231_L	0.890	1.00
326_D	411_M	0.890	1.00
329_S	333_N	0.889	1.00
403_K	406_Q	0.888	1.00
379_E	382_L	0.886	1.00
164_A	170_L	0.882	1.00
98_K	173_E	0.881	1.00
319_K	323_Y	0.881	1.00
180_Y	452_D	0.880	1.00
354_E	502_G	0.879	1.00
425_S	433_K	0.878	1.00
119_Q	123_Y	0.877	1.00
122_E	170_L	0.873	1.00
500_A	503_I	0.867	1.00
323_Y	362_K	0.867	1.00
75_T	83_P	0.866	1.00
327_R	341_P	0.864	1.00
260_L	264_Q	0.861	1.00
181_F	185_T	0.861	1.00
477_F	503_I	0.860	1.00
253_I	268_L	0.859	1.00
88_A	102_F	0.855	1.00
429_V	432_D	0.853	1.00
345_A	512_P	0.853	1.00
490_K	494_A	0.850	1.00
126_K	162_V	0.850	1.00
434_L	442_G	0.848	1.00
458_E	485_Q	0.845	1.00
340_M	348_P	0.839	1.00
369_A	416_L	0.836	1.00
108_V	168_K	0.824	1.00
95_K	101_T	0.823	1.00
481_L	500_A	0.822	1.00
102_F	182_T	0.821	1.00
120_D	124_A	0.818	1.00
71_F	214_S	0.816	1.00
218_F	243_V	0.816	1.00
223_W	229_I	0.816	1.00
87_M	116_V	0.810	1.00
429_V	433_K	0.809	1.00
263_F	271_A	0.803	1.00
454_I	497_L	0.802	1.00
112_N	213_V	0.802	1.00
73_G	191_M	0.800	1.00
108_V	238_W	0.799	1.00
498_K	502_G	0.798	1.00
70_T	220_M	0.798	1.00
93_T	97_G	0.796	1.00
102_F	185_T	0.796	1.00
314_N	378_K	0.795	1.00
292_L	521_V	0.795	1.00
326_D	364_N	0.792	1.00
49_E	252_M	0.790	1.00
164_A	171_K	0.790	1.00
304_K	470_T	0.788	1.00
390_K	395_Y	0.786	1.00
21_C	26_T	0.786	1.00
279_P	282_S	0.786	1.00
483_Q	486_T	0.785	1.00
324_S	366_V	0.782	1.00
14_F	18_L	0.781	1.00
454_I	458_E	0.781	1.00
233_K	245_L	0.780	1.00
323_Y	372_Y	0.779	1.00
104_I	116_V	0.777	1.00
312_L	391_I	0.774	1.00
40_T	245_L	0.774	1.00
55_P	193_I	0.774	1.00
303_Y	408_V	0.773	1.00
15_T	18_L	0.773	1.00
107_G	168_K	0.773	1.00
220_M	229_I	0.773	1.00
38_G	244_K	0.771	1.00
499_K	503_I	0.771	1.00
475_P	478_K	0.770	1.00
323_Y	364_N	0.769	1.00
320_A	373_L	0.769	1.00
21_C	27_G	0.768	1.00
37_K	40_T	0.767	1.00
413_K	418_V	0.766	1.00
10_L	16_L	0.766	1.00
395_Y	422_L	0.766	1.00
312_L	393_L	0.766	1.00
412_W	441_I	0.766	1.00
317_I	378_K	0.763	1.00
284_P	336_Q	0.762	1.00
344_A	501_E	0.759	1.00
261_K	265_A	0.756	1.00
144_I	172_V	0.756	1.00
143_Y	176_N	0.755	1.00
56_G	127_W	0.755	1.00
289_D	292_L	0.754	1.00
36_S	244_K	0.754	1.00
286_L	292_L	0.753	1.00
69_Q	231_L	0.752	1.00
382_L	391_I	0.752	1.00
299_G	447_L	0.751	1.00
98_K	176_N	0.748	1.00
286_L	521_V	0.748	1.00
124_A	193_I	0.744	1.00
259_E	271_A	0.743	1.00
303_Y	441_I	0.742	1.00
86_G	238_W	0.741	1.00
92_E	95_K	0.741	1.00
231_L	248_I	0.741	1.00
406_Q	422_L	0.739	1.00
16_L	19_S	0.737	1.00
468_N	471_G	0.735	1.00
17_V	20_A	0.734	1.00
44_I	270_W	0.733	1.00
395_Y	424_N	0.732	1.00
378_K	382_L	0.731	1.00
260_L	286_L	0.729	1.00
325_L	330_I	0.729	1.00
296_P	517_T	0.728	1.00
130_D	133_N	0.726	1.00
472_W	503_I	0.726	1.00
118_A	122_E	0.725	1.00
143_Y	175_N	0.725	1.00
291_S	523_D	0.725	1.00
301_Y	401_H	0.724	1.00
208_A	211_D	0.724	1.00
308_E	437_Q	0.724	1.00
270_W	526_L	0.724	1.00
74_L	88_A	0.718	1.00
232_E	246_K	0.713	1.00
382_L	390_K	0.713	1.00
42_L	248_I	0.712	1.00
321_L	441_I	0.711	1.00
425_S	429_V	0.708	1.00
40_T	244_K	0.708	1.00
194_N	213_V	0.707	1.00
461_R	504_F	0.707	1.00
325_L	412_W	0.704	1.00
330_I	407_A	0.704	1.00
449_D	455_N	0.704	1.00
235_D	246_K	0.703	1.00
391_I	441_I	0.702	1.00
123_Y	199_E	0.701	1.00
372_Y	376_G	0.701	1.00
509_P	512_P	0.701	1.00
307_T	509_P	0.700	1.00
402_A	424_N	0.699	1.00
70_T	214_S	0.699	1.00
314_N	376_G	0.698	1.00
323_Y	363_D	0.697	1.00
10_L	13_I	0.696	1.00
253_I	259_E	0.695	1.00
412_W	416_L	0.692	1.00
110_W	214_S	0.691	1.00
45_N	253_I	0.691	1.00
321_L	511_A	0.690	1.00
461_R	510_V	0.689	1.00
413_K	420_V	0.688	1.00
493_R	497_L	0.688	1.00
458_E	462_D	0.688	1.00
220_M	223_W	0.687	1.00
395_Y	420_V	0.687	1.00
97_G	101_T	0.686	1.00
49_E	225_H	0.685	1.00
69_Q	248_I	0.684	1.00
116_V	168_K	0.684	1.00
110_W	196_K	0.683	1.00
314_N	317_I	0.682	1.00
91_I	182_T	0.682	1.00
39_K	244_K	0.681	1.00
239_D	243_V	0.680	1.00
162_V	172_V	0.679	1.00
271_A	278_L	0.677	1.00
110_W	116_V	0.676	1.00
496_L	500_A	0.675	1.00
197_I	201_N	0.670	1.00
457_L	461_R	0.669	1.00
233_K	241_D	0.668	1.00
251_V	262_K	0.667	1.00
79_A	530_I	0.666	1.00
110_W	192_P	0.665	1.00
406_Q	409_Q	0.662	1.00
24_G	27_G	0.661	1.00
122_E	163_K	0.659	1.00
117_T	195_E	0.658	1.00
373_L	376_G	0.658	1.00
354_E	501_E	0.658	1.00
66_V	229_I	0.658	1.00
309_A	312_L	0.657	1.00
406_Q	410_E	0.657	1.00
9_T	12_L	0.656	1.00
77_I	83_P	0.655	1.00
77_I	186_A	0.655	1.00
196_K	199_E	0.654	1.00
373_L	418_V	0.653	1.00
330_I	408_V	0.653	1.00
58_A	67_I	0.652	1.00
398_D	401_H	0.652	1.00
430_Y	442_G	0.651	1.00
219_K	236_Q	0.647	1.00
129_L	175_N	0.646	1.00
22_G	25_G	0.645	1.00
305_F	312_L	0.644	1.00
56_G	128_A	0.643	1.00
73_G	215_N	0.643	1.00
461_R	482_N	0.643	1.00
351_K	490_K	0.643	1.00
373_L	416_L	0.642	1.00
104_I	168_K	0.641	1.00
324_S	364_N	0.637	1.00
263_F	523_D	0.636	1.00
179_P	493_R	0.635	1.00
290_G	524_E	0.634	1.00
117_T	168_K	0.633	1.00
309_A	438_D	0.632	1.00
462_D	481_L	0.632	1.00
207_N	211_D	0.631	1.00
126_K	161_A	0.630	1.00
245_L	526_L	0.630	1.00
408_V	420_V	0.630	1.00
366_V	373_L	0.628	1.00
125_W	185_T	0.628	1.00
123_Y	127_W	0.627	1.00
523_D	526_L	0.627	1.00
312_L	317_I	0.627	1.00
255_N	258_T	0.627	1.00
373_L	378_K	0.627	1.00
93_T	182_T	0.625	1.00
355_D	358_E	0.624	1.00
23_F	26_T	0.621	1.00
522_Q	529_V	0.620	1.00
97_G	488_T	0.617	1.00
218_F	247_K	0.617	1.00
98_K	177_P	0.617	1.00
404_I	408_V	0.617	1.00
412_W	418_V	0.617	1.00
207_N	210_D	0.616	1.00
307_T	470_T	0.614	1.00
359_G	362_K	0.614	1.00
11_M	15_T	0.613	1.00
395_Y	405_A	0.611	1.00
427_W	444_M	0.611	1.00
118_A	168_K	0.610	1.00
110_W	215_N	0.609	1.00
11_M	14_F	0.609	1.00
176_N	482_N	0.608	1.00
116_V	124_A	0.608	1.00
83_P	182_T	0.608	1.00
229_I	252_M	0.607	1.00
482_N	485_Q	0.607	1.00
490_K	493_R	0.606	1.00
51_F	60_D	0.605	1.00
308_E	313_D	0.603	1.00
338_E	519_T	0.602	1.00
71_F	215_N	0.601	1.00
71_F	212_Y	0.600	1.00
425_S	430_Y	0.598	1.00
285_T	289_D	0.597	1.00
12_L	15_T	0.597	1.00
114_D	195_E	0.596	1.00
126_K	164_A	0.596	1.00
328_Q	331_V	0.596	1.00
391_I	395_Y	0.595	1.00
13_I	17_V	0.594	1.00
114_D	120_D	0.594	1.00
139_Y	142_Y	0.593	1.00
53_L	223_W	0.593	1.00
478_K	482_N	0.593	1.00
36_S	40_T	0.593	1.00
241_D	244_K	0.591	1.00
256_N	259_E	0.590	1.00
302_W	510_V	0.589	1.00
12_L	16_L	0.588	1.00
58_A	63_S	0.588	1.00
314_N	377_L	0.588	1.00
364_N	411_M	0.588	1.00
218_F	233_K	0.588	1.00
91_I	103_T	0.587	1.00
227_G	251_V	0.587	1.00
352_G	494_A	0.587	1.00
71_F	208_A	0.583	1.00
102_F	170_L	0.583	1.00
301_Y	404_I	0.582	1.00
393_L	441_I	0.582	1.00
118_A	166_N	0.581	1.00
477_F	480_L	0.579	1.00
70_T	212_Y	0.579	1.00
378_K	391_I	0.577	1.00
257_N	261_K	0.577	1.00
263_F	268_L	0.576	1.00
353_F	357_K	0.576	1.00
104_I	108_V	0.575	1.00
123_Y	196_K	0.575	1.00
508_M	511_A	0.575	1.00
307_T	313_D	0.575	1.00
8_V	11_M	0.575	1.00
283_L	294_V	0.574	1.00
378_K	418_V	0.574	1.00
338_E	341_P	0.574	1.00
127_W	198_A	0.573	1.00
404_I	514_Y	0.572	1.00
317_I	377_L	0.572	1.00
9_T	13_I	0.571	1.00
411_M	416_L	0.571	1.00
420_V	441_I	0.570	1.00
46_I	250_M	0.570	1.00
43_N	268_L	0.569	1.00
10_L	17_V	0.569	1.00
209_G	212_Y	0.567	1.00
391_I	420_V	0.564	1.00
131_P	134_E	0.564	1.00
325_L	513_I	0.564	1.00
164_A	169_T	0.564	1.00
487_E	493_R	0.563	1.00
331_V	335_T	0.561	1.00
282_S	286_L	0.561	1.00
362_K	508_M	0.560	1.00
112_N	197_I	0.560	1.00
382_L	419_D	0.560	1.00
287_K	290_G	0.558	1.00
317_I	321_L	0.558	1.00
64_G	188_Y	0.557	1.00
99_T	163_K	0.556	1.00
11_M	17_V	0.556	1.00
484_S	493_R	0.556	1.00
235_D	242_K	0.556	1.00
356_N	498_K	0.554	1.00
356_N	502_G	0.554	1.00
323_Y	369_A	0.553	1.00
330_I	513_I	0.553	1.00
210_D	225_H	0.552	1.00
395_Y	443_R	0.552	1.00
370_K	416_L	0.550	1.00
506_D	509_P	0.550	1.00
390_K	394_S	0.549	1.00
365_D	371_E	0.548	1.00
212_Y	220_M	0.548	1.00
194_N	208_A	0.547	1.00
89_S	104_I	0.546	1.00
325_L	511_A	0.546	1.00
51_F	63_S	0.544	1.00
126_K	195_E	0.543	1.00
291_S	294_V	0.542	1.00
74_L	121_F	0.542	1.00
220_M	231_L	0.542	1.00
9_T	15_T	0.542	1.00
110_W	124_A	0.541	1.00
302_W	444_M	0.541	1.00
234_N	237_Y	0.538	1.00
500_A	504_F	0.538	1.00
353_F	356_N	0.537	1.00
457_L	460_F	0.537	1.00
60_D	427_W	0.537	1.00
334_V	407_A	0.537	1.00
69_Q	250_M	0.536	1.00
9_T	16_L	0.536	1.00
300_V	342_A	0.535	1.00
270_W	522_Q	0.535	1.00
111_S	215_N	0.534	1.00
354_E	358_E	0.534	1.00
446_W	449_D	0.534	1.00
289_D	524_E	0.534	1.00
305_F	322_T	0.533	1.00
36_S	39_K	0.533	1.00
487_E	490_K	0.530	1.00
118_A	169_T	0.529	1.00
141_L	190_Y	0.529	1.00
448_G	456_F	0.528	1.00
488_T	492_K	0.527	1.00
201_N	211_D	0.527	1.00
457_L	500_A	0.527	1.00
408_V	443_R	0.525	1.00
85_E	90_K	0.522	1.00
312_L	441_I	0.521	1.00
328_Q	363_D	0.521	1.00
316_N	371_E	0.520	1.00
296_P	340_M	0.520	1.00
251_V	267_E	0.519	1.00
285_T	288_K	0.518	1.00
501_E	505_I	0.518	1.00
520_W	529_V	0.517	1.00
330_I	334_V	0.517	1.00
431_I	434_L	0.517	1.00
110_W	194_N	0.517	1.00
480_L	484_S	0.516	1.00
23_F	27_G	0.516	1.00
120_D	196_K	0.516	1.00
394_S	440_Q	0.516	1.00
303_Y	513_I	0.515	1.00
116_V	214_S	0.515	1.00
104_I	118_A	0.515	1.00
323_Y	365_D	0.515	1.00
382_L	413_K	0.514	1.00
73_G	102_F	0.514	1.00
278_L	286_L	0.514	1.00
20_A	23_F	0.514	1.00
72_E	239_D	0.513	1.00
311_P	378_K	0.513	1.00
67_I	71_F	0.513	1.00
286_L	289_D	0.512	1.00
338_E	517_T	0.511	1.00
329_S	407_A	0.511	1.00
270_W	520_W	0.510	1.00
75_T	185_T	0.509	1.00
399_D	402_A	0.509	1.00
123_Y	193_I	0.508	1.00
283_L	286_L	0.507	1.00
368_T	375_K	0.507	1.00
266_G	523_D	0.506	1.00
401_H	443_R	0.506	1.00
351_K	494_A	0.505	1.00
78_N	81_G	0.504	1.00
355_D	498_K	0.503	1.00
277_Q	283_L	0.503	1.00
198_A	201_N	0.503	1.00
41_T	230_T	0.502	1.00
76_R	239_D	0.502	1.00
432_D	435_H	0.502	1.00
19_S	23_F	0.501	1.00
95_K	99_T	0.500	1.00
301_Y	516_Y	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4fajA	1	0.9028	100	0.147	Contact Map
4qflA	1	0.8936	100	0.158	Contact Map
4gl8A	1	0.9046	100	0.175	Contact Map
3zs6A	1	0.9083	100	0.18	Contact Map
4tozA	1	0.9211	100	0.184	Contact Map
1xocA	2	0.8899	100	0.187	Contact Map
4wedA	1	0.8606	100	0.187	Contact Map
1jetA	1	0.9248	100	0.191	Contact Map
3drfA	1	0.9028	100	0.197	Contact Map
3m8uA	1	0.8936	100	0.201	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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