GREMLIN Database
OPPC - Oligopeptide transport system permease protein OppC
UniProt: P24139 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 305 (252)
Sequences: 28582 (17851)
Seq/√Len: 1124.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
81_S85_W2.8841.00
189_V216_I2.7871.00
136_D186_R2.6491.00
206_A210_R2.4591.00
192_L197_Y2.4391.00
202_Q208_T2.4301.00
210_R214_K2.4041.00
112_A170_I2.3831.00
124_W139_M2.3701.00
116_L174_T2.3181.00
192_L195_Q2.3061.00
82_K85_W2.2941.00
105_I244_Y2.2581.00
207_K210_R2.2461.00
209_S213_F2.2301.00
72_N75_N2.1681.00
258_T262_D2.1141.00
196_E199_L2.0871.00
198_V216_I2.0271.00
198_V211_L2.0101.00
229_T292_G1.9741.00
98_R259_M1.9661.00
126_S189_V1.9501.00
127_I131_R1.9281.00
94_D97_V1.9081.00
131_R208_T1.8911.00
181_M231_T1.8431.00
119_L123_I1.8371.00
62_M81_S1.8211.00
67_D70_T1.7951.00
131_R135_T1.7561.00
130_F208_T1.7381.00
192_L220_A1.7361.00
129_G189_V1.7361.00
197_Y219_N1.7291.00
134_R138_I1.7261.00
57_A103_A1.7061.00
51_V55_L1.7061.00
89_D93_R1.6911.00
120_I178_W1.6431.00
117_D177_G1.6361.00
96_F100_W1.6361.00
86_F276_F1.6341.00
193_K216_I1.6281.00
120_I123_I1.6201.00
127_I135_T1.6171.00
91_L98_R1.6151.00
108_F112_A1.5701.00
95_I276_F1.5691.00
188_Q191_Q1.5631.00
135_T139_M1.5481.00
143_A182_A1.5321.00
170_I174_T1.5281.00
130_F212_L1.5241.00
263_G273_R1.5221.00
118_L228_M1.5201.00
101_V104_R1.5141.00
139_M182_A1.5051.00
93_R97_V1.4881.00
90_D262_D1.4801.00
43_A294_G1.4791.00
75_N78_K1.4491.00
191_Q195_Q1.4391.00
121_G181_M1.4221.00
125_G129_G1.4191.00
260_A277_P1.4101.00
114_A228_M1.4021.00
59_F62_M1.3911.00
46_G287_G1.3631.00
125_G185_V1.3511.00
141_R144_D1.3511.00
200_A204_L1.3481.00
124_W182_A1.3201.00
153_L157_L1.3161.00
226_V296_R1.3071.00
186_R190_L1.3031.00
129_G193_K1.2991.00
134_R137_E1.2931.00
44_M48_I1.2931.00
99_T280_F1.2911.00
128_S139_M1.2901.00
167_F171_I1.2901.00
126_S212_L1.2691.00
105_I108_F1.2681.00
192_L198_V1.2551.00
121_G185_V1.2531.00
192_L216_I1.2511.00
295_L298_A1.2491.00
86_F96_F1.2451.00
53_I282_C1.2411.00
41_K44_M1.2311.00
271_P275_F1.2311.00
55_L59_F1.2281.00
158_L172_A1.2261.00
174_T178_W1.2231.00
184_I227_T1.2211.00
225_L299_L1.2131.00
296_R300_D1.2061.00
201_S215_H1.1911.00
132_G136_D1.1761.00
54_I82_K1.1731.00
93_R98_R1.1721.00
109_I239_E1.1681.00
189_V220_A1.1541.00
201_S206_A1.1431.00
201_S211_L1.1371.00
146_L179_I1.1251.00
199_L202_Q1.1241.00
50_I283_I1.1241.00
93_R101_V1.1151.00
137_E141_R1.1111.00
81_S84_H1.1071.00
126_S217_V1.0991.00
185_V224_I1.0931.00
294_G298_A1.0921.00
122_V185_V1.0861.00
123_I126_S1.0751.00
185_V189_V1.0741.00
188_Q192_L1.0731.00
86_F99_T1.0601.00
277_P281_I1.0571.00
46_G294_G1.0531.00
178_W182_A1.0521.00
172_A176_T1.0471.00
142_I146_L1.0461.00
155_V172_A1.0441.00
210_R213_F1.0441.00
104_R108_F1.0431.00
263_G274_L1.0361.00
165_G168_T1.0351.00
149_V154_M1.0331.00
84_H94_D1.0301.00
60_A101_V1.0251.00
167_F170_I1.0251.00
48_I52_L1.0191.00
95_I273_R1.0151.00
53_I284_T1.0081.00
232_V288_F1.0061.00
108_F166_L0.9971.00
202_Q211_L0.9961.00
204_L215_H0.9951.00
113_A174_T0.9941.00
136_D140_M0.9921.00
88_T94_D0.9851.00
45_V48_I0.9831.00
185_V220_A0.9821.00
259_M273_R0.9811.00
95_I259_M0.9801.00
140_M182_A0.9781.00
272_W276_F0.9771.00
50_I287_G0.9761.00
64_S97_V0.9671.00
46_G286_F0.9651.00
49_I287_G0.9621.00
201_S204_L0.9551.00
48_I51_V0.9541.00
47_L51_V0.9501.00
276_F279_G0.9491.00
136_D190_L0.9471.00
113_A117_D0.9461.00
138_I142_I0.9451.00
52_L56_M0.9451.00
206_A211_L0.9421.00
97_V101_V0.9411.00
98_R273_R0.9371.00
151_S238_T0.9351.00
78_K81_S0.9341.00
102_G259_M0.9261.00
125_G189_V0.9241.00
137_E140_M0.9181.00
222_G296_R0.9181.00
99_T276_F0.9161.00
208_T211_L0.9141.00
108_F111_V0.9051.00
46_G290_V0.9041.00
113_A173_M0.8981.00
143_A179_I0.8891.00
49_I283_I0.8891.00
162_L168_T0.8891.00
288_F292_G0.8831.00
122_V224_I0.8811.00
88_T92_G0.8781.00
225_L292_G0.8741.00
118_L122_V0.8691.00
173_M238_T0.8651.00
119_L122_V0.8651.00
135_T138_I0.8641.00
287_G291_V0.8561.00
74_L78_K0.8541.00
132_G193_K0.8501.00
227_T231_T0.8471.00
56_M100_W0.8441.00
166_L170_I0.8421.00
220_A223_S0.8411.00
98_R101_V0.8411.00
100_W104_R0.8371.00
47_L291_V0.8371.00
171_I174_T0.8231.00
66_Y83_D0.8221.00
275_F279_G0.8211.00
66_Y97_V0.8181.00
118_L123_I0.8141.00
74_L77_D0.8121.00
189_V193_K0.8111.00
103_A284_T0.8101.00
187_G190_L0.8071.00
97_V100_W0.8051.00
208_T212_L0.8041.00
192_L219_N0.8031.00
213_F216_I0.8031.00
123_I127_I0.8021.00
151_S155_V0.8021.00
118_L181_M0.8001.00
163_P168_T0.8001.00
111_V115_V0.7991.00
259_M277_P0.7921.00
113_A235_A0.7871.00
112_A244_Y0.7781.00
199_L203_T0.7771.00
261_S265_P0.7751.00
129_G190_L0.7741.00
195_Q199_L0.7741.00
158_L168_T0.7701.00
43_A290_V0.7681.00
65_R97_V0.7661.00
124_W178_W0.7641.00
43_A47_L0.7641.00
106_S110_G0.7631.00
297_D303_L0.7631.00
147_W179_I0.7601.00
59_F63_F0.7581.00
128_S136_D0.7581.00
168_T171_I0.7551.00
77_D80_P0.7531.00
281_I285_M0.7521.00
132_G137_E0.7471.00
206_A215_H0.7441.00
262_D265_P0.7421.00
42_L46_G0.7401.00
116_L170_I0.7391.00
261_S264_L0.7391.00
76_A80_P0.7381.00
112_A115_V0.7371.00
188_Q223_S0.7351.00
185_V188_Q0.7321.00
275_F278_A0.7181.00
56_M103_A0.7181.00
62_M271_P0.7131.00
211_L216_I0.7121.00
296_R303_L0.7081.00
100_W103_A0.7071.00
291_V295_L0.7061.00
120_I174_T0.7051.00
209_S212_L0.7051.00
283_I287_G0.7001.00
276_F280_F0.6991.00
58_I62_M0.6991.00
89_D270_Y0.6991.00
61_P104_R0.6971.00
188_Q220_A0.6911.00
177_G180_N0.6901.00
229_T288_F0.6871.00
45_V49_I0.6861.00
53_I283_I0.6821.00
41_K45_V0.6801.00
54_I279_G0.6731.00
285_M289_N0.6691.00
117_D174_T0.6671.00
46_G49_I0.6641.00
176_T179_I0.6601.00
120_I124_W0.6591.00
130_F193_K0.6591.00
121_G125_G0.6571.00
274_L278_A0.6541.00
77_D270_Y0.6481.00
239_E243_S0.6471.00
237_F240_A0.6441.00
151_S154_M0.6431.00
237_F241_F0.6421.00
138_I141_R0.6391.00
169_I239_E0.6391.00
65_R96_F0.6361.00
128_S140_M0.6341.00
66_Y269_Y0.6311.00
50_I288_F0.6301.00
99_T277_P0.6281.00
262_D268_T0.6271.00
44_M47_L0.6261.00
66_Y84_H0.6261.00
114_A231_T0.6251.00
139_M143_A0.6251.00
131_R212_L0.6231.00
140_M143_A0.6221.00
180_N231_T0.6201.00
72_N76_A0.6171.00
181_M227_T0.6171.00
79_P272_W0.6171.00
49_I53_I0.6161.00
84_H88_T0.6161.00
57_A278_A0.6161.00
190_L193_K0.6151.00
110_G235_A0.6121.00
115_V119_L0.6051.00
238_T241_F0.6041.00
107_I111_V0.6031.00
181_M185_V0.6001.00
141_R145_I0.5971.00
114_A232_V0.5961.00
160_V164_K0.5911.00
69_S73_L0.5901.00
206_A209_S0.5901.00
73_L76_A0.5891.00
143_A178_W0.5881.00
157_L161_V0.5881.00
259_M262_D0.5861.00
154_M176_T0.5841.00
146_L178_W0.5821.00
112_A167_F0.5821.00
240_A258_T0.5811.00
236_I240_A0.5741.00
103_A107_I0.5741.00
235_A238_T0.5731.00
168_T172_A0.5731.00
118_L224_I0.5711.00
76_A79_P0.5711.00
129_G136_D0.5711.00
56_M60_A0.5711.00
130_F213_F0.5641.00
177_G231_T0.5601.00
260_A281_I0.5601.00
226_V229_T0.5601.00
61_P101_V0.5581.00
213_F218_P0.5581.00
60_A63_F0.5571.00
290_V294_G0.5561.00
259_M263_G0.5561.00
198_V202_Q0.5541.00
73_L77_D0.5511.00
240_A261_S0.5511.00
175_I178_W0.5501.00
151_S175_I0.5491.00
80_P272_W0.5471.00
64_S101_V0.5471.00
128_S186_R0.5421.00
171_I175_I0.5381.00
78_K88_T0.5381.00
104_R107_I0.5371.00
98_R102_G0.5341.00
179_I182_A0.5341.00
207_K211_L0.5331.00
77_D273_R0.5321.00
159_M163_P0.5311.00
124_W127_I0.5311.00
115_V118_L0.5301.00
293_D296_R0.5301.00
121_G182_A0.5301.00
184_I188_Q0.5281.00
109_I169_I0.5241.00
180_N227_T0.5231.00
50_I291_V0.5231.00
114_A118_L0.5221.00
85_W96_F0.5211.00
174_T177_G0.5211.00
46_G50_I0.5171.00
221_M225_L0.5171.00
144_D147_W0.5151.00
110_G232_V0.5141.00
272_W275_F0.5131.00
240_A262_D0.5121.00
53_I57_A0.5071.00
155_V159_M0.5051.00
133_G136_D0.5041.00
109_I170_I0.5041.00
140_M144_D0.5031.00
231_T235_A0.5021.00
42_L290_V0.5011.00
122_V126_S0.5011.00
155_V241_F0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tquM 1 0.8295 99.9 0.632 Contact Map
3d31C 2 0.7607 99.9 0.649 Contact Map
3tuiA 2 0.6656 99.9 0.657 Contact Map
3rlfF 1 0.9082 99.9 0.661 Contact Map
2onkC 2 0.777 99.9 0.666 Contact Map
3rlfG 1 0.8361 99.9 0.683 Contact Map
4tquN 1 0.8525 99.8 0.683 Contact Map
4ymuD 2 0.6852 99.8 0.689 Contact Map
3j9pD 4 0.777 45.7 0.946 Contact Map
2kogA 1 0.2 21.6 0.955 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0096 seconds.