MENE - BACSU - GREMLIN Contacts

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MENE - 2-succinylbenzoate--CoA ligase

UniProt:	P23971	Sequences: MLTEQPNWLMQRAQLTPERIALIYEDQTVTFAELFAASKRMAEQLAAHSVRKGDTAAILLQNRAEMVYAVHACFLLGVKAVLLNTKLSTHERLFQLEDSGSGFLLTDSSFEKKEYEHIVQTIDVDELMKEAAEEIEIEAYMQMDATATLMYTSGTTGKPKGVQQTFGNHYFSAVSSALNLGITEQDRWLIALPLFHISGLSALFKSVIYGMTVVLHQRFSVSDVLHSINRHEVTMISAVQTMLASLLEETNRCPESIRCILLGGGPAPLPLLEECREKGFPVFQSYGMTETCSQIVTLSPEFSMEKLGSAGKPLFSCEIKIERDGQVCEPYEHGEIMVKGPNVMKSYFNRESANEASFQNGWLKTGDLGYLDNEGFLYVLDRRSDLIISGGENIYPAEVESVLLSHPAVAEAGVSGAEDKKWGKVPHAYLVLHKPVSAGELTDYCKERLAKYKIPAKFFVLDRLPRNASNKLLRNQLKDARKGELL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	486 (469)
Sequences:	71654 (51696)
Seq/√Len:	2387.1

ECOLI - ENTF ACSA AAS LCFA ENTE FADK PRPE CAIC MENE PAAK
BACSU - MENE SRFAC PPSE LCFA LCFB ACSA YNGI YDAB DHBE PPSC PPSB YTCI YHFT DLTA DHBF PKSJ SRFAB SRFAA PPSD PKSN PPSA
HALSA - Q9HRY8 Q9HQU8 Q9HSM3 Q9HQN8 Q9HNK0 Q9HQ43
SULSO - Q97UW7 Q97UX8 Q97YK9 Q97U22 Q97WQ0 Q97VT6 Q97VU7 Q97XW4 Q97WQ9 Q97WK0 Q97UF6 Q97V27 Q97WS5 Q980E4 Q97X52 Q97XW5 Q97VJ6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
146_T	163_Q	3.832	1.00
406_H	444_Y	3.150	1.00
336_I	369_G	3.080	1.00
39_K	75_L	2.892	1.00
318_E	339_K	2.863	1.00
350_R	353_A	2.851	1.00
98_D	151_Y	2.795	1.00
57_A	101_S	2.758	1.00
54_D	102_G	2.756	1.00
165_T	345_K	2.740	1.00
35_F	75_L	2.714	1.00
370_Y	378_Y	2.710	1.00
50_V	78_V	2.662	1.00
23_I	212_T	2.593	1.00
335_E	364_K	2.509	1.00
187_R	212_T	2.443	1.00
388_I	393_N	2.396	1.00
20_I	28_T	2.374	1.00
100_G	349_N	2.348	1.00
411_E	466_R	2.344	1.00
16_T	19_R	2.307	1.00
404_L	412_A	2.304	1.00
320_K	327_V	2.276	1.00
55_T	81_V	2.268	1.00
44_Q	48_H	2.255	1.00
10_M	35_F	2.244	1.00
322_E	326_Q	2.187	1.00
403_L	428_A	2.184	1.00
337_M	364_K	2.180	1.00
37_A	68_Y	2.177	1.00
333_H	368_L	2.153	1.00
94_F	158_K	2.129	1.00
12_R	16_T	2.120	1.00
372_D	378_Y	2.106	1.00
69_A	105_L	2.099	1.00
98_D	350_R	2.092	1.00
35_F	39_K	2.062	1.00
473_L	476_Q	2.061	1.00
226_H	230_R	2.047	1.00
405_S	448_R	2.042	1.00
24_Y	64_A	2.030	1.00
385_D	474_R	2.030	1.00
353_A	356_A	2.022	1.00
427_H	459_F	2.021	1.00
73_C	78_V	2.007	1.00
142_Q	145_A	1.966	1.00
309_S	378_Y	1.941	1.00
186_D	258_R	1.939	1.00
370_Y	380_L	1.910	1.00
320_K	337_M	1.903	1.00
351_E	355_E	1.898	1.00
372_D	376_F	1.883	1.00
41_M	68_Y	1.869	1.00
269_L	273_E	1.852	1.00
186_D	234_T	1.851	1.00
23_I	28_T	1.834	1.00
52_K	145_A	1.818	1.00
18_E	32_A	1.812	1.00
51_R	54_D	1.809	1.00
93_L	97_E	1.803	1.00
46_A	76_L	1.751	1.00
398_E	453_K	1.745	1.00
53_G	145_A	1.741	1.00
410_A	433_H	1.730	1.00
371_L	377_L	1.714	1.00
476_Q	479_D	1.713	1.00
38_S	75_L	1.706	1.00
23_I	231_H	1.698	1.00
400_E	414_V	1.683	1.00
32_A	36_A	1.671	1.00
11_Q	15_L	1.670	1.00
404_L	411_E	1.668	1.00
333_H	380_L	1.667	1.00
214_V	233_V	1.652	1.00
67_V	203_L	1.645	1.00
415_S	429_Y	1.644	1.00
61_Q	107_D	1.632	1.00
165_T	168_N	1.631	1.00
330_P	371_L	1.608	1.00
30_T	33_E	1.595	1.00
232_E	256_S	1.590	1.00
414_V	428_A	1.559	1.00
57_A	83_L	1.556	1.00
146_T	345_K	1.550	1.00
429_Y	477_L	1.547	1.00
431_V	464_L	1.541	1.00
123_D	126_E	1.540	1.00
430_L	460_V	1.531	1.00
74_F	147_A	1.526	1.00
55_T	79_K	1.526	1.00
12_R	15_L	1.521	1.00
238_A	243_L	1.516	1.00
352_S	356_A	1.515	1.00
29_V	68_Y	1.508	1.00
151_Y	161_G	1.504	1.00
177_A	209_Y	1.502	1.00
39_K	43_E	1.499	1.00
432_L	460_V	1.497	1.00
295_I	338_V	1.484	1.00
223_D	226_H	1.482	1.00
408_A	440_E	1.480	1.00
444_Y	448_R	1.479	1.00
402_V	448_R	1.477	1.00
17_P	32_A	1.464	1.00
10_M	75_L	1.457	1.00
20_I	23_I	1.450	1.00
418_E	424_K	1.448	1.00
389_S	394_I	1.447	1.00
206_S	211_M	1.444	1.00
144_D	167_G	1.443	1.00
281_P	299_S	1.441	1.00
56_A	73_C	1.441	1.00
149_L	348_F	1.426	1.00
243_L	260_I	1.425	1.00
273_E	277_E	1.425	1.00
189_L	233_V	1.416	1.00
13_A	35_F	1.415	1.00
20_I	212_T	1.409	1.00
321_I	369_G	1.407	1.00
163_Q	348_F	1.405	1.00
306_K	374_E	1.403	1.00
178_L	315_F	1.401	1.00
329_E	332_E	1.400	1.00
99_S	151_Y	1.393	1.00
19_R	185_Q	1.392	1.00
467_N	473_L	1.390	1.00
288_M	363_L	1.384	1.00
437_S	440_E	1.382	1.00
369_G	379_V	1.380	1.00
241_T	265_G	1.378	1.00
442_T	458_F	1.376	1.00
29_V	64_A	1.376	1.00
96_L	101_S	1.370	1.00
168_N	292_C	1.369	1.00
220_S	223_D	1.361	1.00
163_Q	346_S	1.355	1.00
368_L	383_R	1.346	1.00
187_R	214_V	1.338	1.00
430_L	458_F	1.335	1.00
183_T	186_D	1.334	1.00
57_A	96_L	1.333	1.00
24_Y	27_Q	1.328	1.00
333_H	370_Y	1.326	1.00
339_K	362_W	1.321	1.00
81_V	99_S	1.321	1.00
143_M	167_G	1.319	1.00
322_E	328_C	1.319	1.00
186_D	235_M	1.319	1.00
21_A	34_L	1.315	1.00
296_V	319_I	1.313	1.00
227_S	231_H	1.312	1.00
344_M	358_F	1.307	1.00
56_A	78_V	1.306	1.00
357_S	363_L	1.303	1.00
319_I	338_V	1.301	1.00
443_D	447_E	1.299	1.00
216_H	227_S	1.290	1.00
312_K	376_F	1.285	1.00
429_Y	461_L	1.284	1.00
44_Q	127_L	1.281	1.00
55_T	149_L	1.276	1.00
387_I	396_P	1.273	1.00
419_D	425_V	1.271	1.00
306_K	376_F	1.271	1.00
411_E	431_V	1.268	1.00
71_H	207_V	1.265	1.00
50_V	54_D	1.265	1.00
53_G	345_K	1.262	1.00
41_M	72_A	1.254	1.00
98_D	349_N	1.253	1.00
427_H	457_K	1.252	1.00
262_L	267_A	1.251	1.00
320_K	362_W	1.251	1.00
167_G	341_P	1.247	1.00
442_T	446_K	1.243	1.00
417_A	427_H	1.233	1.00
55_T	348_F	1.228	1.00
94_F	98_D	1.221	1.00
79_K	146_T	1.217	1.00
98_D	158_K	1.216	1.00
187_R	233_V	1.208	1.00
335_E	383_R	1.207	1.00
37_A	40_R	1.205	1.00
397_A	401_S	1.197	1.00
25_E	217_Q	1.187	1.00
444_Y	447_E	1.187	1.00
163_Q	345_K	1.187	1.00
58_I	69_A	1.183	1.00
336_I	379_V	1.174	1.00
298_L	376_F	1.173	1.00
50_V	56_A	1.172	1.00
429_Y	478_K	1.165	1.00
416_G	424_K	1.165	1.00
385_D	397_A	1.163	1.00
35_F	136_E	1.161	1.00
198_S	237_S	1.159	1.00
392_E	452_Y	1.159	1.00
89_T	93_L	1.156	1.00
236_I	257_I	1.151	1.00
149_L	161_G	1.150	1.00
425_V	456_A	1.150	1.00
337_M	362_W	1.147	1.00
34_L	71_H	1.140	1.00
248_E	274_E	1.139	1.00
446_K	451_K	1.138	1.00
36_A	40_R	1.134	1.00
72_A	76_L	1.129	1.00
313_P	319_I	1.129	1.00
141_M	145_A	1.127	1.00
438_A	460_V	1.127	1.00
28_T	231_H	1.118	1.00
27_Q	64_A	1.116	1.00
328_C	332_E	1.110	1.00
228_I	256_S	1.108	1.00
10_M	39_K	1.106	1.00
432_L	436_V	1.103	1.00
89_T	113_K	1.102	1.00
235_M	259_C	1.102	1.00
244_A	271_L	1.099	1.00
97_E	158_K	1.097	1.00
428_A	458_F	1.096	1.00
164_Q	168_N	1.096	1.00
59_L	92_R	1.095	1.00
21_A	31_F	1.095	1.00
247_L	274_E	1.086	1.00
29_V	37_A	1.081	1.00
37_A	65_E	1.076	1.00
152_T	162_V	1.075	1.00
323_R	383_R	1.075	1.00
33_E	36_A	1.071	1.00
48_H	120_Q	1.070	1.00
44_Q	47_A	1.068	1.00
446_K	454_I	1.067	1.00
144_D	165_T	1.067	1.00
425_V	457_K	1.066	1.00
439_G	443_D	1.066	1.00
66_M	194_L	1.064	1.00
222_S	249_E	1.063	1.00
23_I	214_V	1.055	1.00
50_V	103_F	1.050	1.00
42_A	75_L	1.048	1.00
34_L	68_Y	1.045	1.00
214_V	231_H	1.043	1.00
390_G	422_W	1.041	1.00
83_L	92_R	1.040	1.00
41_M	105_L	1.040	1.00
386_L	395_Y	1.033	1.00
440_E	443_D	1.030	1.00
274_E	278_K	1.029	1.00
187_R	234_T	1.028	1.00
445_C	454_I	1.027	1.00
310_A	379_V	1.027	1.00
438_A	458_F	1.026	1.00
353_A	357_S	1.023	1.00
317_C	342_N	1.022	1.00
168_N	343_V	1.020	1.00
268_P	271_L	1.017	1.00
214_V	227_S	1.014	1.00
410_A	431_V	1.012	1.00
192_L	198_S	1.002	1.00
417_A	457_K	1.002	1.00
402_V	405_S	0.999	1.00
406_H	441_L	0.995	1.00
188_W	206_S	0.995	1.00
461_L	480_A	0.993	1.00
186_D	211_M	0.993	1.00
461_L	464_L	0.989	1.00
339_K	360_N	0.987	1.00
338_V	365_T	0.986	1.00
91_E	453_K	0.986	1.00
298_L	309_S	0.984	1.00
54_D	78_V	0.976	1.00
464_L	472_L	0.976	1.00
400_E	474_R	0.969	1.00
90_H	448_R	0.969	1.00
450_A	453_K	0.966	1.00
245_S	421_K	0.963	1.00
38_S	72_A	0.960	1.00
153_S	469_S	0.957	1.00
475_N	479_D	0.955	1.00
19_R	212_T	0.953	1.00
270_P	274_E	0.952	1.00
44_Q	131_A	0.951	1.00
55_T	100_G	0.949	1.00
340_G	343_V	0.948	1.00
29_V	34_L	0.947	1.00
413_G	464_L	0.946	1.00
309_S	376_F	0.946	1.00
296_V	377_L	0.946	1.00
41_M	69_A	0.946	1.00
476_Q	480_A	0.944	1.00
387_I	426_P	0.942	1.00
162_V	344_M	0.942	1.00
114_E	118_I	0.939	1.00
87_L	95_Q	0.939	1.00
94_F	151_Y	0.938	1.00
94_F	97_E	0.935	1.00
22_L	67_V	0.931	1.00
171_F	341_P	0.926	1.00
171_F	316_S	0.925	1.00
150_M	289_T	0.924	1.00
48_H	103_F	0.922	1.00
90_H	94_F	0.920	1.00
443_D	446_K	0.918	1.00
319_I	377_L	0.918	1.00
60_L	63_R	0.916	1.00
45_L	73_C	0.914	1.00
20_I	30_T	0.913	1.00
402_V	445_C	0.912	1.00
27_Q	37_A	0.910	1.00
321_I	328_C	0.910	1.00
243_L	275_C	0.908	1.00
84_N	195_F	0.906	1.00
267_A	272_L	0.903	1.00
9_L	13_A	0.903	1.00
70_V	80_A	0.902	1.00
107_D	110_F	0.897	1.00
57_A	104_L	0.896	1.00
172_S	293_S	0.894	1.00
244_A	268_P	0.893	1.00
64_A	68_Y	0.892	1.00
90_H	93_L	0.890	1.00
274_E	277_E	0.889	1.00
189_L	216_H	0.889	1.00
438_A	442_T	0.888	1.00
405_S	444_Y	0.887	1.00
306_K	372_D	0.886	1.00
43_E	46_A	0.886	1.00
368_L	381_D	0.885	1.00
34_L	38_S	0.880	1.00
319_I	336_I	0.879	1.00
219_F	242_M	0.878	1.00
406_H	440_E	0.875	1.00
389_S	416_G	0.873	1.00
259_C	283_F	0.871	1.00
173_A	208_I	0.871	1.00
206_S	213_V	0.867	1.00
46_A	51_R	0.866	1.00
46_A	137_I	0.865	1.00
261_L	285_S	0.862	1.00
440_E	444_Y	0.859	1.00
43_E	137_I	0.858	1.00
229_N	253_C	0.857	1.00
58_I	80_A	0.854	1.00
23_I	187_R	0.854	1.00
164_Q	292_C	0.848	1.00
65_E	68_Y	0.847	1.00
197_I	288_M	0.846	1.00
322_E	332_E	0.841	1.00
61_Q	109_S	0.840	1.00
70_V	200_L	0.838	1.00
45_L	105_L	0.837	1.00
11_Q	14_Q	0.837	1.00
418_E	421_K	0.837	1.00
359_Q	364_K	0.836	1.00
10_M	14_Q	0.834	1.00
42_A	76_L	0.828	1.00
325_G	337_M	0.824	1.00
147_A	166_F	0.823	1.00
33_E	37_A	0.823	1.00
8_W	174_V	0.822	1.00
35_F	38_S	0.822	1.00
164_Q	344_M	0.820	1.00
237_S	294_Q	0.820	1.00
50_V	76_L	0.818	1.00
321_I	377_L	0.818	1.00
22_L	64_A	0.817	1.00
354_N	358_F	0.815	1.00
73_C	80_A	0.815	1.00
94_F	350_R	0.812	1.00
67_V	215_L	0.808	1.00
197_I	293_S	0.807	1.00
358_F	364_K	0.804	1.00
257_I	260_I	0.804	1.00
413_G	477_L	0.801	1.00
352_S	355_E	0.800	1.00
389_S	456_A	0.798	1.00
336_I	377_L	0.798	1.00
37_A	64_A	0.798	1.00
57_A	81_V	0.795	1.00
441_L	458_F	0.792	1.00
20_I	24_Y	0.790	1.00
187_R	232_E	0.788	1.00
408_A	433_H	0.783	1.00
318_E	362_W	0.775	1.00
68_Y	72_A	0.774	1.00
126_E	129_K	0.772	1.00
191_A	242_M	0.769	1.00
291_T	363_L	0.769	1.00
291_T	343_V	0.767	1.00
234_T	258_R	0.766	1.00
8_W	12_R	0.763	1.00
19_R	184_E	0.762	1.00
9_L	71_H	0.762	1.00
27_Q	65_E	0.762	1.00
40_R	44_Q	0.760	1.00
70_V	74_F	0.759	1.00
251_N	274_E	0.759	1.00
385_D	400_E	0.759	1.00
339_K	361_G	0.758	1.00
243_L	262_L	0.758	1.00
431_V	463_R	0.757	1.00
120_Q	123_D	0.754	1.00
442_T	454_I	0.753	1.00
350_R	354_N	0.750	1.00
34_L	67_V	0.750	1.00
222_S	226_H	0.749	1.00
141_M	166_F	0.748	1.00
259_C	281_P	0.748	1.00
146_T	165_T	0.748	1.00
239_V	242_M	0.745	1.00
185_Q	234_T	0.742	1.00
331_Y	373_N	0.741	1.00
108_S	123_D	0.740	1.00
320_K	339_K	0.739	1.00
147_A	169_H	0.737	1.00
244_A	274_E	0.736	1.00
413_G	472_L	0.736	1.00
7_N	11_Q	0.735	1.00
244_A	248_E	0.733	1.00
410_A	432_L	0.733	1.00
429_Y	480_A	0.732	1.00
369_G	377_L	0.732	1.00
128_M	131_A	0.732	1.00
408_A	432_L	0.731	1.00
81_V	101_S	0.723	1.00
73_C	76_L	0.722	1.00
60_L	66_M	0.720	1.00
127_L	131_A	0.719	1.00
182_I	186_D	0.718	1.00
198_S	263_G	0.718	1.00
9_L	35_F	0.717	1.00
63_R	107_D	0.715	1.00
59_L	104_L	0.715	1.00
291_T	338_V	0.714	1.00
172_S	292_C	0.713	1.00
95_Q	161_G	0.713	1.00
270_P	273_E	0.710	1.00
148_T	164_Q	0.710	1.00
28_T	212_T	0.709	1.00
364_K	383_R	0.708	1.00
330_P	373_N	0.707	1.00
90_H	158_K	0.705	1.00
223_D	227_S	0.704	1.00
80_A	200_L	0.703	1.00
403_L	412_A	0.702	1.00
16_T	32_A	0.702	1.00
249_E	252_R	0.701	1.00
445_C	449_L	0.700	1.00
418_E	423_G	0.697	1.00
228_I	233_V	0.696	1.00
417_A	425_V	0.695	1.00
291_T	295_I	0.694	1.00
182_I	235_M	0.693	1.00
260_I	275_C	0.689	1.00
7_N	10_M	0.688	1.00
18_E	30_T	0.688	1.00
226_H	229_N	0.687	1.00
41_M	45_L	0.686	1.00
177_A	205_K	0.686	1.00
106_T	110_F	0.685	1.00
229_N	256_S	0.685	1.00
397_A	400_E	0.682	1.00
51_R	78_V	0.682	1.00
319_I	369_G	0.682	1.00
283_F	299_S	0.680	1.00
201_S	237_S	0.679	1.00
57_A	99_S	0.679	1.00
285_S	294_Q	0.679	1.00
402_V	444_Y	0.679	1.00
418_E	422_W	0.677	1.00
172_S	201_S	0.675	1.00
69_A	73_C	0.675	1.00
59_L	110_F	0.673	1.00
56_A	103_F	0.671	1.00
12_R	210_G	0.671	1.00
189_L	227_S	0.670	1.00
196_H	392_E	0.669	1.00
237_S	285_S	0.668	1.00
244_A	270_P	0.667	1.00
46_A	139_A	0.666	1.00
188_W	235_M	0.666	1.00
216_H	224_V	0.665	1.00
13_A	17_P	0.662	1.00
183_T	258_R	0.660	1.00
168_N	345_K	0.659	1.00
314_L	317_C	0.659	1.00
190_I	202_A	0.658	1.00
70_V	204_F	0.656	1.00
46_A	136_E	0.654	1.00
267_A	282_V	0.652	1.00
369_G	380_L	0.652	1.00
8_W	170_Y	0.650	1.00
42_A	72_A	0.650	1.00
43_E	132_A	0.649	1.00
229_N	255_E	0.647	1.00
88_S	91_E	0.647	1.00
389_S	426_P	0.646	1.00
413_G	474_R	0.646	1.00
41_M	44_Q	0.645	1.00
323_R	335_E	0.645	1.00
51_R	102_G	0.645	1.00
343_V	363_L	0.643	1.00
136_E	139_A	0.641	1.00
39_K	136_E	0.640	1.00
24_Y	217_Q	0.639	1.00
179_N	315_F	0.638	1.00
327_V	337_M	0.636	1.00
129_K	132_A	0.636	1.00
228_I	236_I	0.634	1.00
436_V	441_L	0.633	1.00
110_F	113_K	0.630	1.00
389_S	422_W	0.630	1.00
52_K	141_M	0.629	1.00
52_K	139_A	0.629	1.00
396_P	414_V	0.626	1.00
189_L	228_I	0.626	1.00
288_M	291_T	0.625	1.00
71_H	204_F	0.625	1.00
410_A	434_K	0.625	1.00
100_G	348_F	0.625	1.00
465_P	477_L	0.624	1.00
60_L	69_A	0.623	1.00
47_A	131_A	0.623	1.00
286_Y	295_I	0.623	1.00
182_I	211_M	0.623	1.00
430_L	441_L	0.622	1.00
424_K	478_K	0.622	1.00
38_S	41_M	0.621	1.00
158_K	350_R	0.619	1.00
191_A	239_V	0.619	1.00
396_P	474_R	0.618	1.00
202_A	237_S	0.618	1.00
14_Q	35_F	0.617	1.00
60_L	105_L	0.617	1.00
29_V	33_E	0.616	1.00
144_D	345_K	0.615	1.00
174_V	208_I	0.614	1.00
276_R	281_P	0.613	1.00
148_T	169_H	0.613	1.00
81_V	151_Y	0.613	1.00
172_S	294_Q	0.612	1.00
192_L	237_S	0.611	1.00
98_D	348_F	0.609	1.00
419_D	422_W	0.608	1.00
321_I	371_L	0.608	1.00
344_M	357_S	0.608	1.00
46_A	138_E	0.608	1.00
284_Q	308_G	0.608	1.00
43_E	136_E	0.607	1.00
429_Y	459_F	0.607	1.00
225_L	254_P	0.607	1.00
415_S	478_K	0.606	1.00
409_V	430_L	0.605	1.00
36_A	133_E	0.602	1.00
106_T	111_E	0.602	1.00
38_S	42_A	0.601	1.00
201_S	293_S	0.601	1.00
227_S	230_R	0.599	1.00
47_A	130_E	0.598	1.00
49_S	78_V	0.597	1.00
108_S	125_D	0.597	1.00
212_T	231_H	0.595	1.00
40_R	132_A	0.594	1.00
55_T	349_N	0.594	1.00
173_A	204_F	0.594	1.00
68_Y	124_V	0.593	1.00
442_T	445_C	0.592	1.00
60_L	107_D	0.591	1.00
65_E	107_D	0.591	1.00
288_M	365_T	0.590	1.00
219_F	224_V	0.589	1.00
40_R	43_E	0.588	1.00
16_T	210_G	0.586	1.00
403_L	445_C	0.585	1.00
409_V	412_A	0.584	1.00
22_L	213_V	0.583	1.00
124_V	128_M	0.582	1.00
31_F	211_M	0.582	1.00
451_K	454_I	0.582	1.00
8_W	208_I	0.581	1.00
260_I	280_F	0.580	1.00
350_R	356_A	0.580	1.00
310_A	369_G	0.579	1.00
148_T	200_L	0.578	1.00
331_Y	370_Y	0.577	1.00
224_V	228_I	0.576	1.00
198_S	261_L	0.576	1.00
23_I	26_D	0.575	1.00
190_I	213_V	0.575	1.00
384_S	424_K	0.573	1.00
45_L	103_F	0.573	1.00
266_P	379_V	0.573	1.00
271_L	274_E	0.572	1.00
149_L	163_Q	0.572	1.00
16_T	184_E	0.572	1.00
193_P	196_H	0.571	1.00
459_F	480_A	0.570	1.00
420_K	423_G	0.569	1.00
402_V	449_L	0.568	1.00
387_I	416_G	0.568	1.00
267_A	284_Q	0.566	1.00
60_L	106_T	0.565	1.00
39_K	46_A	0.565	1.00
20_I	187_R	0.564	1.00
79_K	348_F	0.564	1.00
432_L	435_P	0.562	1.00
79_K	149_L	0.562	1.00
70_V	203_L	0.562	1.00
98_D	161_G	0.561	1.00
321_I	336_I	0.560	1.00
273_E	276_R	0.560	1.00
262_L	282_V	0.558	1.00
201_S	294_Q	0.558	1.00
438_A	457_K	0.558	1.00
236_I	260_I	0.556	1.00
129_K	133_E	0.555	1.00
174_V	177_A	0.554	1.00
195_F	392_E	0.553	1.00
400_E	428_A	0.552	1.00
396_P	416_G	0.552	1.00
399_V	426_P	0.551	1.00
58_I	73_C	0.550	1.00
188_W	211_M	0.549	1.00
82_L	150_M	0.549	1.00
250_T	278_K	0.549	1.00
125_D	129_K	0.548	1.00
401_S	405_S	0.548	1.00
58_I	66_M	0.547	1.00
275_C	282_V	0.547	1.00
43_E	47_A	0.547	1.00
454_I	458_F	0.546	1.00
31_F	207_V	0.543	1.00
408_A	444_Y	0.543	1.00
406_H	409_V	0.543	1.00
191_A	238_A	0.543	1.00
411_E	464_L	0.542	1.00
55_T	101_S	0.542	1.00
333_H	383_R	0.542	1.00
145_A	166_F	0.541	1.00
7_N	140_Y	0.541	1.00
263_G	285_S	0.540	1.00
103_F	120_Q	0.538	1.00
389_S	424_K	0.538	1.00
43_E	133_E	0.538	1.00
252_R	278_K	0.537	1.00
296_V	310_A	0.536	1.00
41_M	124_V	0.536	1.00
346_S	351_E	0.535	1.00
187_R	190_I	0.534	1.00
457_K	460_V	0.533	1.00
189_L	224_V	0.533	1.00
174_V	178_L	0.532	1.00
327_V	371_L	0.532	1.00
99_S	161_G	0.532	1.00
157_G	395_Y	0.530	1.00
87_L	92_R	0.528	1.00
285_S	297_T	0.528	1.00
190_I	215_L	0.527	1.00
50_V	102_G	0.527	1.00
419_D	423_G	0.524	1.00
401_S	404_L	0.524	1.00
37_A	41_M	0.524	1.00
298_L	301_E	0.523	1.00
338_V	343_V	0.523	1.00
190_I	199_G	0.522	1.00
245_S	248_E	0.522	1.00
79_K	82_L	0.522	1.00
91_E	398_E	0.519	1.00
417_A	429_Y	0.519	1.00
332_E	370_Y	0.518	1.00
22_L	29_V	0.517	1.00
173_A	205_K	0.517	1.00
237_S	263_G	0.517	1.00
99_S	149_L	0.517	1.00
44_Q	128_M	0.516	1.00
182_I	205_K	0.515	1.00
321_I	334_G	0.514	1.00
10_M	136_E	0.514	1.00
83_L	96_L	0.512	1.00
37_A	128_M	0.511	1.00
45_L	78_V	0.509	1.00
137_I	141_M	0.509	1.00
240_Q	265_G	0.509	1.00
351_E	354_N	0.508	1.00
381_D	396_P	0.507	1.00
272_L	276_R	0.507	1.00
412_A	445_C	0.507	1.00
225_L	246_L	0.506	1.00
238_A	260_I	0.506	1.00
81_V	95_Q	0.506	1.00
162_V	289_T	0.506	1.00
273_E	307_L	0.505	1.00
262_L	284_Q	0.503	1.00
234_T	256_S	0.503	1.00
228_I	232_E	0.503	1.00
61_Q	110_F	0.502	1.00
381_D	397_A	0.502	1.00
156_T	160_K	0.501	1.00
202_A	206_S	0.500	1.00
318_E	360_N	0.500	1.00
263_G	294_Q	0.500	1.00
475_N	478_K	0.500	1.00
9_L	38_S	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3tsyA	2	0.7922	100	0.106	Contact Map
2vsqA	1	0.9979	100	0.107	Contact Map
1mdbA	1	0.9897	100	0.111	Contact Map
3etcA	2	0.9547	100	0.112	Contact Map
3g7sA	2	0.9095	100	0.115	Contact Map
3o83A	1	0.7901	100	0.12	Contact Map
4lgcA	1	0.7572	100	0.121	Contact Map
1pg4A	1	0.9938	100	0.123	Contact Map
3ni2A	1	0.9856	100	0.124	Contact Map
1amuA	1	0.9774	100	0.125	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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