GREMLIN Database
MEND - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
UniProt: P23970 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 580 (532)
Sequences: 14267 (9114)
Seq/√Len: 395.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
516_H519_A4.9601.00
389_I535_K3.7491.00
483_N551_E3.7351.00
58_G88_A3.5801.00
243_K264_K3.5681.00
526_S540_P3.4231.00
237_N342_E3.2811.00
23_T70_R3.1311.00
530_S533_E3.0871.00
210_S347_G2.9431.00
527_C553_K2.9321.00
393_L539_A2.8391.00
237_N338_S2.7601.00
67_A447_T2.7051.00
335_C340_F2.6621.00
226_C238_I2.5661.00
524_T546_G2.5501.00
526_S548_H2.5501.00
263_D419_D2.4951.00
389_I392_H2.4911.00
24_D47_S2.4661.00
529_A533_E2.4311.00
212_V314_I2.3671.00
292_F337_A2.3661.00
18_A45_D2.3521.00
440_A453_L2.3301.00
526_S537_A2.3231.00
286_P289_V2.2241.00
524_T540_P2.1981.00
513_D516_H2.1971.00
76_C85_F2.1941.00
316_I340_F2.1541.00
527_C551_E2.1521.00
392_H535_K2.1431.00
71_P160_Q2.1391.00
11_G39_L2.1051.00
291_R294_P2.0701.00
461_Y521_Y2.0691.00
100_I156_A2.0641.00
51_Q57_A2.0371.00
89_V101_V2.0341.00
517_A520_L2.0161.00
83_A87_P1.9951.00
215_M288_V1.9821.00
215_M312_Q1.9761.00
215_M331_H1.9641.00
224_I242_S1.9611.00
103_T168_H1.9401.00
515_K525_Y1.9311.00
216_L290_I1.9181.00
528_P537_A1.9021.00
15_D19_L1.8871.00
244_A345_M1.8861.00
151_L169_V1.8701.00
244_A349_T1.8681.00
71_P100_I1.8361.00
206_R343_E1.8271.00
120_N123_F1.8231.00
395_P398_S1.8171.00
242_S249_I1.8111.00
539_A543_D1.8071.00
260_G263_D1.8031.00
460_F464_L1.8001.00
444_C476_P1.7991.00
211_D214_E1.7861.00
391_Q416_E1.7681.00
62_L66_K1.7641.00
471_K523_G1.7611.00
11_G42_A1.7561.00
240_A244_A1.7411.00
524_T548_H1.7401.00
533_E536_T1.7391.00
535_K539_A1.7391.00
214_E218_E1.7321.00
123_F126_G1.7261.00
205_D208_S1.7161.00
481_L549_L1.7091.00
224_I290_I1.6971.00
541_Q550_I1.6761.00
399_S443_V1.6761.00
7_T15_D1.6741.00
239_I243_K1.6601.00
403_G455_I1.6381.00
529_A553_K1.6351.00
360_K364_V1.6261.00
388_R392_H1.6251.00
224_I247_Y1.6171.00
236_E240_A1.5991.00
390_L454_V1.5911.00
137_L147_Y1.5871.00
435_G439_S1.5861.00
403_G459_S1.5771.00
292_F316_I1.5611.00
536_T540_P1.5531.00
385_N531_W1.5511.00
519_A524_T1.5511.00
27_V48_V1.5471.00
246_Q266_T1.5421.00
37_A48_V1.5411.00
15_D18_A1.5391.00
323_R334_H1.5301.00
285_R360_K1.5291.00
425_Y443_V1.5041.00
393_L535_K1.5001.00
68_K446_G1.4991.00
362_Q365_N1.4971.00
208_S211_D1.4931.00
515_K527_C1.4881.00
129_V168_H1.4881.00
444_C475_I1.4821.00
357_W361_W1.4771.00
13_F171_V1.4701.00
130_K165_G1.4501.00
249_I259_N1.4501.00
355_S359_E1.4491.00
359_E363_F1.4421.00
16_E153_S1.4411.00
213_A347_G1.4411.00
219_A222_G1.4381.00
385_N389_I1.4351.00
536_T539_A1.4351.00
470_A523_G1.4341.00
467_L523_G1.4261.00
312_Q330_A1.4221.00
133_T169_V1.4221.00
13_F152_A1.4181.00
56_S466_G1.4151.00
470_A477_L1.4131.00
102_L171_V1.4131.00
216_L288_V1.4121.00
464_L517_A1.4031.00
389_I393_L1.3961.00
480_I538_Y1.3951.00
480_I550_I1.3811.00
395_P450_P1.3721.00
51_Q60_F1.3711.00
108_H174_R1.3701.00
398_S450_P1.3691.00
386_L552_I1.3641.00
240_A345_M1.3641.00
85_F101_V1.3631.00
20_S156_A1.3531.00
399_S447_T1.3511.00
71_P156_A1.3511.00
47_S473_L1.3501.00
138_P178_M1.3441.00
89_V99_I1.3441.00
445_E475_I1.3371.00
452_T542_A1.3351.00
24_D445_E1.3241.00
100_I159_A1.3211.00
241_L245_L1.3181.00
213_A344_I1.3171.00
444_C450_P1.3151.00
423_R449_A1.3121.00
480_I552_I1.3091.00
219_A288_V1.3041.00
394_V452_T1.3001.00
20_S153_S1.2971.00
58_G85_F1.2891.00
209_L347_G1.2851.00
288_V314_I1.2821.00
238_I341_A1.2821.00
204_V340_F1.2811.00
241_L345_M1.2801.00
450_P542_A1.2791.00
223_M286_P1.2791.00
82_A103_T1.2791.00
478_T541_Q1.2761.00
396_E419_D1.2731.00
515_K519_A1.2721.00
292_F341_A1.2711.00
441_M470_A1.2711.00
18_A44_P1.2681.00
241_L341_A1.2651.00
476_P546_G1.2571.00
147_Y150_T1.2561.00
517_A521_Y1.2561.00
365_N369_R1.2461.00
381_S552_I1.2451.00
453_L479_V1.2341.00
338_S342_E1.2311.00
135_S148_I1.2311.00
476_P545_P1.2281.00
210_S214_E1.2251.00
433_I462_H1.2241.00
152_A169_V1.2241.00
363_F367_R1.2231.00
324_D329_S1.2181.00
516_H520_L1.2171.00
336_N339_V1.2091.00
49_H445_E1.2021.00
239_I260_G1.1991.00
26_V64_L1.1991.00
10_I39_L1.1971.00
523_G549_L1.1971.00
485_D511_G1.1951.00
381_S386_L1.1931.00
534_F552_I1.1911.00
150_T154_R1.1911.00
206_R347_G1.1861.00
362_Q366_G1.1801.00
64_L446_G1.1791.00
518_A523_G1.1731.00
62_L91_E1.1731.00
339_V342_E1.1711.00
213_A217_A1.1711.00
240_A243_K1.1681.00
65_A98_P1.1651.00
211_D215_M1.1631.00
23_T47_S1.1621.00
16_E152_A1.1601.00
399_S451_V1.1561.00
25_A40_C1.1551.00
8_H11_G1.1521.00
237_N345_M1.1521.00
172_P175_E1.1521.00
343_E346_A1.1501.00
90_V430_A1.1501.00
9_Y148_I1.1481.00
203_S343_E1.1361.00
230_H238_I1.1351.00
22_I73_L1.1351.00
518_A549_L1.1321.00
366_G370_E1.1291.00
109_E174_R1.1291.00
224_I241_L1.1261.00
239_I259_N1.1231.00
237_N240_A1.1221.00
251_A267_V1.1211.00
67_A443_V1.1191.00
526_S550_I1.1181.00
537_A550_I1.1151.00
468_L472_K1.1141.00
12_S180_D1.1121.00
133_T154_R1.1101.00
62_L97_V1.1051.00
396_E420_R1.1031.00
158_E167_V1.1011.00
212_V331_H1.0971.00
8_H179_P1.0951.00
359_E362_Q1.0931.00
524_T544_K1.0791.00
222_G287_D1.0781.00
242_S259_N1.0771.00
56_S463_D1.0771.00
239_I264_K1.0761.00
240_A342_E1.0741.00
534_F538_Y1.0731.00
39_L42_A1.0721.00
108_H178_M1.0721.00
212_V333_I1.0701.00
236_E239_I1.0691.00
221_K285_R1.0681.00
93_H166_P1.0681.00
83_A124_L1.0651.00
268_I282_R1.0621.00
217_A349_T1.0611.00
24_D49_H1.0551.00
12_S149_R1.0551.00
135_S151_L1.0531.00
74_L85_F1.0531.00
204_V343_E1.0511.00
444_C451_V1.0491.00
224_I238_I1.0451.00
303_L306_K1.0441.00
226_C230_H1.0441.00
256_N262_H1.0441.00
243_K266_T1.0441.00
525_Y549_L1.0431.00
63_G67_A1.0431.00
213_A348_L1.0411.00
133_T151_L1.0401.00
363_F366_G1.0401.00
13_F102_L1.0391.00
518_A525_Y1.0351.00
329_S332_M1.0341.00
250_L268_I1.0341.00
33_S36_L1.0321.00
242_S266_T1.0291.00
217_A348_L1.0281.00
450_P478_T1.0281.00
58_G74_L1.0251.00
49_H473_L1.0221.00
291_R296_P1.0211.00
397_N449_A1.0171.00
478_T548_H1.0161.00
7_T179_P1.0071.00
183_D186_F1.0051.00
485_D553_K1.0051.00
86_Y124_L1.0041.00
218_E312_Q1.0021.00
394_V400_L1.0001.00
111_R134_D0.9991.00
339_V343_E0.9921.00
444_C448_K0.9911.00
223_M250_L0.9911.00
460_F481_L0.9901.00
400_L415_F0.9871.00
540_P543_D0.9861.00
132_F168_H0.9841.00
528_P534_F0.9841.00
401_F451_V0.9831.00
160_Q164_M0.9821.00
544_K548_H0.9821.00
528_P533_E0.9781.00
259_N264_K0.9741.00
481_L514_F0.9741.00
203_S339_V0.9741.00
436_V453_L0.9731.00
240_A349_T0.9661.00
13_F36_L0.9661.00
76_C101_V0.9651.00
401_F453_L0.9621.00
467_L549_L0.9591.00
437_V460_F0.9591.00
237_N341_A0.9541.00
360_K363_F0.9541.00
235_K239_I0.9461.00
86_Y128_F0.9451.00
387_Y454_V0.9401.00
382_F558_S0.9391.00
523_G547_L0.9391.00
515_K551_E0.9381.00
219_A287_D0.9381.00
25_A73_L0.9371.00
74_L101_V0.9351.00
70_R160_Q0.9321.00
482_V554_T0.9321.00
11_G15_D0.9261.00
40_C46_I0.9261.00
464_L521_Y0.9261.00
207_E210_S0.9261.00
541_Q548_H0.9241.00
36_L171_V0.9201.00
105_D170_N0.9201.00
467_L479_V0.9161.00
478_T542_A0.9141.00
58_G99_I0.9131.00
474_G545_P0.9121.00
241_L348_L0.9121.00
154_R158_E0.9121.00
386_L482_V0.9111.00
82_A125_F0.9111.00
468_L521_Y0.9071.00
66_K97_V0.9071.00
184_E187_G0.9041.00
206_R210_S0.9031.00
420_R423_R0.9031.00
212_V288_V0.9021.00
537_A541_Q0.9011.00
385_N534_F0.9011.00
223_M289_V0.9011.00
393_L538_Y0.8961.00
308_D311_I0.8961.00
83_A90_V0.8951.00
218_E288_V0.8921.00
444_C546_G0.8891.00
460_F549_L0.8891.00
214_E217_A0.8861.00
533_E537_A0.8861.00
358_L362_Q0.8861.00
38_V41_A0.8851.00
470_A479_V0.8841.00
361_W364_V0.8841.00
519_A525_Y0.8791.00
16_E20_S0.8781.00
442_G446_G0.8731.00
124_L128_F0.8711.00
60_F470_A0.8711.00
478_T550_I0.8701.00
361_W365_N0.8701.00
411_V454_V0.8681.00
391_Q415_F0.8681.00
458_L487_G0.8681.00
354_S358_L0.8661.00
281_K285_R0.8661.00
7_T12_S0.8641.00
63_G439_S0.8631.00
212_V215_M0.8631.00
129_V132_F0.8601.00
470_A547_L0.8591.00
131_F158_E0.8581.00
262_H267_V0.8571.00
224_I292_F0.8521.00
281_K284_L0.8491.00
333_I340_F0.8481.00
89_V125_F0.8471.00
477_L547_L0.8451.00
86_Y125_F0.8451.00
537_A540_P0.8441.00
96_R163_P0.8441.00
215_M314_I0.8441.00
122_H132_F0.8431.00
485_D556_R0.8421.00
16_E19_L0.8421.00
472_K510_T0.8411.00
316_I333_I0.8401.00
387_Y482_V0.8371.00
24_D64_L0.8331.00
221_K287_D0.8331.00
398_S452_T0.8311.00
540_P544_K0.8301.00
454_V482_V0.8251.00
73_L100_I0.8241.00
8_H39_L0.8241.00
389_I534_F0.8241.00
288_V312_Q0.8201.00
277_D281_K0.8201.00
87_P432_G0.8191.00
234_D237_N0.8161.00
209_L343_E0.8161.00
393_L542_A0.8151.00
263_D396_E0.8131.00
502_F505_L0.8121.00
35_P177_L0.8101.00
320_G334_H0.8031.00
343_E347_G0.8031.00
122_H134_D0.8011.00
280_L284_L0.8001.00
67_A425_Y0.8001.00
226_C251_A0.7991.00
230_H258_R0.7991.00
171_V176_P0.7991.00
452_T480_I0.7981.00
100_I160_Q0.7961.00
204_V209_L0.7921.00
245_L348_L0.7921.00
483_N553_K0.7921.00
323_R332_M0.7901.00
212_V340_F0.7881.00
17_F73_L0.7881.00
397_N420_R0.7871.00
217_A346_A0.7871.00
441_M475_I0.7861.00
159_A167_V0.7861.00
131_F151_L0.7851.00
513_D527_C0.7851.00
513_D519_A0.7851.00
342_E346_A0.7841.00
59_F432_G0.7831.00
506_F509_P0.7801.00
356_E359_E0.7791.00
64_L70_R0.7781.00
461_Y464_L0.7781.00
29_P50_V0.7781.00
478_T545_P0.7771.00
226_C249_I0.7741.00
23_T64_L0.7741.00
471_K547_L0.7721.00
9_Y138_P0.7711.00
532_D536_T0.7651.00
25_A75_I0.7641.00
75_I102_L0.7641.00
407_P459_S0.7641.00
33_S75_I0.7641.00
105_D111_R0.7631.00
301_V304_W0.7601.00
130_K167_V0.7581.00
364_V368_F0.7581.00
89_V128_F0.7571.00
387_Y415_F0.7571.00
65_A99_I0.7561.00
67_A446_G0.7541.00
211_D331_H0.7521.00
394_V398_S0.7521.00
381_S531_W0.7511.00
290_I316_I0.7501.00
65_A97_V0.7471.00
437_V479_V0.7461.00
33_S37_A0.7441.00
22_I156_A0.7411.00
402_V424_I0.7401.00
51_Q56_S0.7391.00
26_V60_F0.7391.00
20_S160_Q0.7381.00
525_Y551_E0.7381.00
222_G247_Y0.7371.00
55_R84_N0.7371.00
18_A23_T0.7361.00
440_A477_L0.7361.00
356_E360_K0.7341.00
364_V367_R0.7331.00
450_P476_P0.7291.00
471_K510_T0.7251.00
228_E254_L0.7251.00
23_T45_D0.7251.00
217_A347_G0.7241.00
340_F343_E0.7231.00
131_F167_V0.7211.00
461_Y512_L0.7211.00
454_V480_I0.7191.00
28_C85_F0.7191.00
365_N368_F0.7181.00
491_S495_Q0.7181.00
402_V426_S0.7181.00
36_L176_P0.7181.00
479_V523_G0.7181.00
204_V339_V0.7171.00
315_V329_S0.7161.00
77_T117_Q0.7151.00
123_F127_N0.7141.00
491_S508_T0.7121.00
103_T170_N0.7121.00
235_K421_P0.7111.00
342_E345_M0.7101.00
234_D338_S0.7091.00
76_C103_T0.7051.00
480_I534_F0.7021.00
381_S530_S0.7011.00
208_S212_V0.7001.00
38_V42_A0.7001.00
83_A86_Y0.6981.00
131_F155_A0.6971.00
149_R153_S0.6971.00
471_K522_G0.6971.00
131_F154_R0.6961.00
366_G369_R0.6961.00
345_M349_T0.6961.00
403_G436_V0.6961.00
224_I249_I0.6951.00
97_V435_G0.6931.00
233_A422_F0.6931.00
138_P149_R0.6931.00
470_A475_I0.6931.00
271_Y283_K0.6921.00
391_Q419_D0.6921.00
373_Q388_R0.6901.00
253_P412_D0.6901.00
402_V411_V0.6891.00
134_D170_N0.6810.99
58_G101_V0.6810.99
217_A351_A0.6800.99
452_T478_T0.6800.99
246_Q265_S0.6790.99
260_G419_D0.6780.99
401_F443_V0.6770.99
158_E163_P0.6770.99
437_V455_I0.6760.99
245_L266_T0.6730.99
259_N267_V0.6730.99
14_I44_P0.6730.99
215_M218_E0.6720.99
138_P180_D0.6720.99
208_S333_I0.6720.99
251_A262_H0.6710.99
486_G491_S0.6700.99
386_L480_I0.6700.99
90_V128_F0.6700.99
437_V466_G0.6680.99
108_H172_P0.6680.99
223_M283_K0.6670.99
460_F514_F0.6660.99
125_F168_H0.6650.99
151_L154_R0.6640.99
528_P550_I0.6640.99
453_L459_S0.6640.99
225_V291_R0.6630.99
36_L75_I0.6620.99
183_D187_G0.6620.99
461_Y514_F0.6610.99
222_G288_V0.6600.99
346_A349_T0.6600.99
201_T336_N0.6560.99
92_A99_I0.6560.99
523_G546_G0.6550.99
257_L262_H0.6530.99
220_E287_D0.6510.99
64_L68_K0.6500.99
93_H130_K0.6500.99
112_E118_A0.6500.99
195_V198_K0.6490.99
304_W307_D0.6480.99
504_D508_T0.6460.99
154_R157_G0.6440.99
370_E373_Q0.6410.99
108_H136_A0.6410.99
545_P548_H0.6410.99
237_N241_L0.6400.99
35_P176_P0.6400.99
24_D70_R0.6400.99
441_M469_A0.6380.99
59_F91_E0.6380.99
25_A46_I0.6370.99
260_G264_K0.6370.99
476_P547_L0.6360.99
512_L520_L0.6360.99
47_S448_K0.6350.99
445_E473_L0.6340.99
323_R329_S0.6330.99
513_D551_E0.6320.99
84_N87_P0.6310.99
138_P175_E0.6310.99
52_I472_K0.6300.99
340_F344_I0.6300.99
440_A451_V0.6300.99
76_C82_A0.6300.99
291_R313_Q0.6290.99
537_A548_H0.6290.99
379_D531_W0.6280.99
216_L245_L0.6280.99
242_S245_L0.6250.99
229_L317_D0.6230.99
357_W360_K0.6230.99
379_D530_S0.6230.99
266_T358_L0.6220.99
155_A169_V0.6210.99
390_L480_I0.6210.99
386_L534_F0.6200.99
337_A342_E0.6200.99
63_G442_G0.6190.99
64_L72_V0.6190.99
238_I242_S0.6180.99
505_L508_T0.6170.99
157_G161_K0.6160.99
221_K357_W0.6160.99
9_Y12_S0.6150.99
438_S466_G0.6130.99
397_N450_P0.6130.99
225_V252_D0.6120.99
361_W369_R0.6100.99
354_S357_W0.6100.99
203_S206_R0.6070.99
526_S544_K0.6070.99
204_V335_C0.6070.99
209_L344_I0.6060.99
239_I420_R0.6060.99
265_S362_Q0.6060.99
100_I169_V0.6060.99
100_I167_V0.6050.99
401_F425_Y0.6050.99
530_S536_T0.6050.99
116_P431_N0.6050.99
147_Y151_L0.6020.99
272_D275_L0.6020.99
94_Y430_A0.6020.99
401_F436_V0.6020.99
358_L361_W0.6010.99
174_R178_M0.6000.99
232_D336_N0.6000.99
455_I463_D0.6000.99
139_E147_Y0.5980.99
478_T546_G0.5980.99
437_V470_A0.5980.99
399_S449_A0.5960.99
130_K161_K0.5960.99
130_K158_E0.5940.99
455_I479_V0.5940.99
443_V451_V0.5940.99
385_N535_K0.5930.99
7_T11_G0.5920.98
83_A119_I0.5910.98
23_T68_K0.5900.98
314_I331_H0.5900.98
121_Q168_H0.5890.98
53_D84_N0.5880.98
425_Y435_G0.5870.98
135_S172_P0.5860.98
512_L517_A0.5860.98
60_F445_E0.5840.98
225_V294_P0.5840.98
399_S425_Y0.5830.98
102_L169_V0.5820.98
108_H175_E0.5820.98
220_E354_S0.5810.98
368_F371_H0.5780.98
18_A46_I0.5770.98
246_Q351_A0.5750.98
71_P159_A0.5750.98
217_A220_E0.5750.98
460_F479_V0.5750.98
52_I468_L0.5740.98
357_W368_F0.5740.98
474_G546_G0.5720.98
402_V436_V0.5720.98
234_D337_A0.5720.98
240_A346_A0.5710.98
16_E149_R0.5710.98
479_V549_L0.5710.98
372_L388_R0.5680.98
47_S445_E0.5680.98
156_A160_Q0.5680.98
461_Y465_N0.5680.98
491_S556_R0.5680.98
102_L152_A0.5670.98
244_A348_L0.5660.98
57_A74_L0.5650.98
67_A399_S0.5650.98
368_F372_L0.5650.98
62_L439_S0.5650.98
98_P159_A0.5630.98
201_T205_D0.5630.98
251_A258_R0.5630.98
254_L428_R0.5620.98
108_H137_L0.5620.98
239_I266_T0.5620.98
28_C487_G0.5590.98
31_S77_T0.5570.98
384_G558_S0.5570.98
85_F103_T0.5550.98
220_E356_E0.5540.98
468_L512_L0.5540.98
490_F494_P0.5540.98
317_D322_W0.5530.98
209_L333_I0.5520.98
407_P482_V0.5520.98
133_T167_V0.5510.98
206_R346_A0.5510.98
103_T121_Q0.5510.98
205_D339_V0.5510.98
130_K163_P0.5490.98
513_D520_L0.5490.98
538_Y542_A0.5490.98
471_K474_G0.5480.98
257_L423_R0.5480.98
225_V289_V0.5470.97
418_Q423_R0.5460.97
469_A475_I0.5460.97
540_P548_H0.5450.97
236_E243_K0.5450.97
85_F88_A0.5450.97
387_Y391_Q0.5450.97
30_G77_T0.5440.97
464_L520_L0.5430.97
91_E95_S0.5430.97
524_T545_P0.5420.97
377_S532_D0.5420.97
58_G89_V0.5400.97
49_H469_A0.5400.97
16_E156_A0.5400.97
526_S536_T0.5400.97
28_C51_Q0.5400.97
33_S104_A0.5390.97
380_V555_D0.5390.97
26_V445_E0.5380.97
383_E410_D0.5380.97
73_L156_A0.5380.97
31_S493_L0.5370.97
357_W369_R0.5360.97
256_N418_Q0.5360.97
14_I40_C0.5360.97
212_V290_I0.5360.97
282_R361_W0.5350.97
239_I249_I0.5350.97
528_P536_T0.5340.97
322_W325_P0.5340.97
478_T544_K0.5330.97
228_E295_M0.5320.97
214_E351_A0.5320.97
208_S331_H0.5320.97
201_T339_V0.5320.97
65_A71_P0.5310.97
212_V344_I0.5310.97
239_I242_S0.5300.97
65_A72_V0.5300.97
9_Y178_M0.5300.97
357_W365_N0.5270.97
246_Q354_S0.5250.97
279_E284_L0.5240.97
41_A503_E0.5230.97
466_G469_A0.5230.97
75_I78_S0.5230.97
122_H126_G0.5220.97
490_F493_L0.5210.97
107_P110_L0.5210.97
519_A526_S0.5200.97
455_I459_S0.5170.96
66_K95_S0.5170.96
531_W535_K0.5160.96
397_N421_P0.5160.96
402_V405_S0.5160.96
403_G453_L0.5150.96
313_Q327_Q0.5140.96
387_Y411_V0.5140.96
217_A352_T0.5120.96
163_P319_D0.5120.96
398_S449_A0.5100.96
246_Q358_L0.5090.96
149_R152_A0.5090.96
157_G160_Q0.5080.96
411_V424_I0.5080.96
55_R463_D0.5070.96
394_V542_A0.5050.96
21_G70_R0.5050.96
444_C447_T0.5040.96
438_S463_D0.5040.96
367_R370_E0.5030.96
437_V464_L0.5030.96
90_V119_I0.5030.96
59_F88_A0.5020.96
104_A176_P0.5020.96
125_F132_F0.5020.96
467_L471_K0.5020.96
483_N514_F0.5010.96
401_F439_S0.5010.96
93_H165_G0.5010.96
255_S258_R0.5000.96
251_A256_N0.5000.96
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2x7jA 4 0.9966 100 0.161 Contact Map
1ozhA 4 0.9328 100 0.179 Contact Map
1ybhA 4 0.9638 100 0.179 Contact Map
3lq1A 4 0.8862 100 0.18 Contact Map
1t9bA 2 0.9672 100 0.183 Contact Map
2panA 3 0.9603 100 0.184 Contact Map
4rjjA 5 0.9431 100 0.19 Contact Map
2uz1A 4 0.9345 100 0.191 Contact Map
2ihtA 4 0.9276 100 0.192 Contact Map
3eyaA 5 0.9052 100 0.194 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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