PHOR - BACSU - GREMLIN Contacts

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PHOR - Alkaline phosphatase synthesis sensor protein PhoR

UniProt:	P23545	Sequences: MNKYRVRLFSVFVVCMILVFCVLGLFLQQLFETSDQRKAEEHIEKEAKYLASLLDAGNLNNQANEKIIKDAGGALDVSASVIDTDGKVLYGSNGRSADSQKVQALVSGHEGILSTTDNKLYYGLSLRSEGEKTGYVLLSASEKSDGLKGELWGMLTASLCTAFIVIVYFYSSMTSRYKRSIESATNVATELSKGNYDARTYGGYIRRSDKLGHAMNSLAIDLMEMTRTQEMQRDRLLTVIENIGSGLIMIDGRGFINLVNRSYAKQFHINPNHMLRRLYHDAFEHEEVIQLVEDIFMTETKKCKLLRLPIKIERRYFEVDGVPIMGPDDEWKGIVLVFHDMTETKKLEQMRKDFVANVSHELKTPITSIKGFTETLLDGAMEDKEALSEFLSIILKESERLQSLVQDLLDLSKIEQQNFTLSIETFEPAKMLGEIETLLKHKADEKGISLHLNVPKDPQYVSGDPYRLKQVFLNLVNNALTYTPEGGSVAINVKPREKDIQIEVADSGIGIQKEEIPRIFERFYRVDKDRSRNSGGTGLGLAIVKHLIEAHEGKIDVTSELGRGTVFTVTLKRAAEKSA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	579 (553)
Sequences:	6396 (5679)
Seq/√Len:	241.5

ECOLI - ATOS BARA DCUS RCSD ARCB NARX RCSC DPIB NARQ TORS EVGS PHOR BAES CUSS CREC GLRK RSTB CPXA YEDV PHOQ QSEC ZRAS ENVZ NTRB
BACSU - PHOR YYCG RESE DCTS CITS MALK KINE KINC KINA YCLK YVRG YKOH CSSS KIND
HALSA - Q9HQ16 Q9HQG5 O51970 Q9HR10 Q9HRE4 Q9HRG1 Q9HQB9 Q9HNM2 BAT Q9HNA6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
560_E	563_R	4.995	1.00
505_A	566_V	4.726	1.00
190_E	195_N	4.650	1.00
373_T	394_I	4.251	1.00
206_R	209_D	3.833	1.00
483_T	507_S	3.821	1.00
453_N	492_N	3.417	1.00
516_I	557_V	3.400	1.00
557_V	567_F	3.341	1.00
245_S	339_H	3.261	1.00
451_H	488_S	3.200	1.00
204_Y	209_D	3.168	1.00
502_I	569_V	3.136	1.00
251_D	255_F	3.103	1.00
471_V	547_L	3.082	1.00
556_D	568_T	3.041	1.00
548_I	569_V	2.944	1.00
490_A	505_A	2.922	1.00
426_F	463_G	2.903	1.00
488_S	507_S	2.857	1.00
492_N	503_E	2.845	1.00
545_K	549_E	2.795	1.00
463_G	551_H	2.746	1.00
199_R	216_N	2.715	1.00
471_V	548_I	2.696	1.00
492_N	505_A	2.587	1.00
483_T	487_G	2.520	1.00
544_V	555_I	2.518	1.00
427_E	430_K	2.506	1.00
233_R	237_L	2.503	1.00
503_E	566_V	2.492	1.00
344_T	348_E	2.488	1.00
494_K	501_Q	2.443	1.00
499_D	570_T	2.420	1.00
511_I	515_E	2.415	1.00
548_I	553_G	2.384	1.00
451_H	490_A	2.350	1.00
547_L	551_H	2.287	1.00
429_A	493_V	2.281	1.00
188_A	218_L	2.269	1.00
482_Y	525_R	2.259	1.00
463_G	468_L	2.251	1.00
377_L	392_S	2.228	1.00
506_D	510_G	2.227	1.00
558_T	566_V	2.220	1.00
83_D	87_K	2.219	1.00
501_Q	568_T	2.197	1.00
345_K	348_E	2.185	1.00
349_Q	352_K	2.185	1.00
559_S	563_R	2.182	1.00
503_E	568_T	2.175	1.00
559_S	562_G	2.169	1.00
343_E	346_K	2.168	1.00
348_E	352_K	2.167	1.00
277_R	281_D	2.159	1.00
449_S	488_S	2.147	1.00
559_S	565_T	2.091	1.00
479_A	489_V	2.088	1.00
501_Q	570_T	2.086	1.00
496_R	501_Q	2.084	1.00
472_F	502_I	2.081	1.00
248_I	263_Y	2.078	1.00
494_K	503_E	2.017	1.00
232_Q	235_R	2.016	1.00
453_N	490_A	2.012	1.00
215_M	218_L	2.004	1.00
424_E	465_P	1.975	1.00
487_G	507_S	1.969	1.00
440_K	444_D	1.938	1.00
261_R	265_K	1.935	1.00
425_T	462_S	1.915	1.00
7_R	206_R	1.887	1.00
219_A	222_L	1.863	1.00
246_G	266_Q	1.854	1.00
191_L	218_L	1.844	1.00
512_Q	515_E	1.842	1.00
356_A	361_E	1.832	1.00
248_I	256_I	1.828	1.00
199_R	219_A	1.812	1.00
483_T	489_V	1.802	1.00
467_R	470_Q	1.769	1.00
348_E	351_R	1.761	1.00
262_S	265_K	1.741	1.00
170_Y	174_T	1.736	1.00
377_L	395_L	1.715	1.00
134_G	141_S	1.714	1.00
477_N	481_T	1.707	1.00
184_A	215_M	1.698	1.00
554_K	570_T	1.694	1.00
236_L	240_I	1.693	1.00
230_E	233_R	1.680	1.00
454_V	493_V	1.661	1.00
377_L	388_S	1.635	1.00
47_A	51_A	1.635	1.00
188_A	215_M	1.634	1.00
434_E	469_K	1.629	1.00
490_A	507_S	1.617	1.00
305_L	345_K	1.613	1.00
246_G	338_F	1.609	1.00
199_R	220_I	1.608	1.00
519_I	557_V	1.607	1.00
511_I	519_I	1.606	1.00
520_F	555_I	1.595	1.00
199_R	223_M	1.594	1.00
370_K	399_E	1.585	1.00
278_L	281_D	1.582	1.00
516_I	559_S	1.574	1.00
471_V	544_V	1.570	1.00
467_R	547_L	1.561	1.00
197_D	223_M	1.551	1.00
191_L	219_A	1.547	1.00
549_E	554_K	1.547	1.00
237_L	241_E	1.546	1.00
512_Q	561_L	1.544	1.00
102_V	105_L	1.530	1.00
439_L	473_L	1.528	1.00
464_D	467_R	1.521	1.00
370_K	398_S	1.521	1.00
78_S	91_G	1.515	1.00
248_I	336_L	1.508	1.00
51_A	55_D	1.507	1.00
518_R	521_E	1.500	1.00
513_K	560_E	1.477	1.00
553_G	571_L	1.471	1.00
472_F	476_V	1.458	1.00
341_M	345_K	1.457	1.00
472_F	504_V	1.448	1.00
39_A	43_I	1.445	1.00
402_Q	406_Q	1.437	1.00
432_L	493_V	1.432	1.00
104_A	108_G	1.430	1.00
222_L	225_M	1.428	1.00
290_Q	294_D	1.421	1.00
427_E	460_Y	1.407	1.00
269_I	273_H	1.406	1.00
43_I	47_A	1.400	1.00
548_I	571_L	1.400	1.00
481_T	527_D	1.399	1.00
376_L	387_L	1.398	1.00
218_L	222_L	1.392	1.00
359_S	364_T	1.390	1.00
372_F	390_F	1.389	1.00
130_G	134_G	1.383	1.00
243_I	247_L	1.377	1.00
432_L	472_F	1.375	1.00
40_E	44_E	1.364	1.00
443_A	489_V	1.362	1.00
369_I	394_I	1.361	1.00
468_L	551_H	1.361	1.00
188_A	211_L	1.337	1.00
558_T	568_T	1.331	1.00
38_K	42_H	1.323	1.00
270_N	273_H	1.312	1.00
189_T	210_K	1.301	1.00
134_G	137_L	1.297	1.00
233_R	236_L	1.293	1.00
222_L	226_T	1.289	1.00
429_A	454_V	1.289	1.00
556_D	570_T	1.286	1.00
429_A	433_G	1.286	1.00
403_S	466_Y	1.285	1.00
187_V	215_M	1.284	1.00
557_V	565_T	1.282	1.00
347_L	351_R	1.271	1.00
82_I	88_V	1.270	1.00
205_I	209_D	1.259	1.00
326_G	330_E	1.256	1.00
471_V	551_H	1.256	1.00
294_D	298_T	1.254	1.00
373_T	398_S	1.241	1.00
174_T	178_K	1.241	1.00
25_L	29_Q	1.237	1.00
368_S	397_E	1.231	1.00
185_T	210_K	1.229	1.00
177_Y	180_S	1.228	1.00
520_F	557_V	1.217	1.00
47_A	50_L	1.216	1.00
520_F	567_F	1.216	1.00
188_A	214_A	1.210	1.00
361_E	365_P	1.208	1.00
318_E	344_T	1.206	1.00
187_V	200_T	1.202	1.00
428_P	502_I	1.202	1.00
100_Q	104_A	1.201	1.00
134_G	138_L	1.196	1.00
425_T	460_Y	1.195	1.00
513_K	516_I	1.181	1.00
398_S	401_L	1.179	1.00
225_M	229_Q	1.177	1.00
432_L	491_I	1.168	1.00
439_L	480_L	1.165	1.00
515_E	526_V	1.161	1.00
434_E	465_P	1.159	1.00
435_I	469_K	1.150	1.00
493_V	502_I	1.150	1.00
397_E	400_R	1.146	1.00
372_F	393_I	1.145	1.00
443_A	480_L	1.141	1.00
240_I	260_N	1.138	1.00
481_T	525_R	1.136	1.00
436_E	452_L	1.128	1.00
346_K	349_Q	1.121	1.00
470_Q	547_L	1.120	1.00
125_S	134_G	1.119	1.00
175_S	179_R	1.117	1.00
67_I	70_D	1.116	1.00
361_E	364_T	1.109	1.00
119_K	125_S	1.109	1.00
499_D	554_K	1.108	1.00
108_G	111_G	1.103	1.00
519_I	567_F	1.100	1.00
361_E	543_I	1.098	1.00
200_T	212_G	1.097	1.00
461_V	571_L	1.092	1.00
259_V	263_Y	1.091	1.00
354_F	359_S	1.089	1.00
468_L	569_V	1.088	1.00
264_A	271_P	1.079	1.00
455_P	494_K	1.079	1.00
358_V	408_L	1.074	1.00
380_A	387_L	1.074	1.00
521_E	524_Y	1.073	1.00
250_I	256_I	1.070	1.00
511_I	565_T	1.069	1.00
264_A	270_N	1.067	1.00
304_K	307_R	1.065	1.00
447_G	485_E	1.065	1.00
373_T	395_L	1.065	1.00
259_V	264_A	1.065	1.00
184_A	188_A	1.057	1.00
376_L	391_L	1.055	1.00
475_L	569_V	1.054	1.00
435_I	476_V	1.053	1.00
392_S	396_K	1.051	1.00
433_G	452_L	1.051	1.00
354_F	357_N	1.046	1.00
246_G	260_N	1.046	1.00
318_E	339_H	1.046	1.00
41_E	44_E	1.041	1.00
397_E	409_L	1.038	1.00
357_N	363_K	1.038	1.00
46_E	51_A	1.036	1.00
438_L	473_L	1.036	1.00
195_N	198_A	1.034	1.00
101_K	105_L	1.033	1.00
46_E	49_Y	1.031	1.00
476_V	491_I	1.030	1.00
428_P	500_I	1.030	1.00
202_G	206_R	1.029	1.00
232_Q	236_L	1.029	1.00
408_L	412_S	1.027	1.00
239_V	249_M	1.027	1.00
527_D	535_G	1.024	1.00
23_L	27_L	1.024	1.00
249_M	333_G	1.024	1.00
409_L	413_K	1.022	1.00
347_L	350_M	1.021	1.00
384_K	387_L	1.019	1.00
114_S	121_Y	1.017	1.00
216_N	219_A	1.009	1.00
293_E	297_M	1.009	1.00
40_E	43_I	1.007	1.00
353_D	357_N	1.002	1.00
29_Q	32_E	1.002	1.00
359_S	363_K	1.000	1.00
472_F	569_V	0.999	1.00
260_N	342_T	0.994	1.00
80_S	91_G	0.993	1.00
99_S	103_Q	0.990	1.00
240_I	258_L	0.987	1.00
356_A	362_L	0.984	1.00
453_N	494_K	0.984	1.00
290_Q	293_E	0.983	1.00
45_K	48_K	0.981	1.00
346_K	350_M	0.981	1.00
471_V	569_V	0.979	1.00
261_R	264_A	0.978	1.00
211_L	218_L	0.978	1.00
46_E	50_L	0.977	1.00
475_L	544_V	0.977	1.00
38_K	41_E	0.976	1.00
231_M	235_R	0.975	1.00
423_I	462_S	0.973	1.00
373_T	391_L	0.970	1.00
50_L	53_L	0.968	1.00
395_L	399_E	0.968	1.00
27_L	31_F	0.966	1.00
122_Y	125_S	0.959	1.00
115_T	121_Y	0.958	1.00
200_T	216_N	0.957	1.00
475_L	567_F	0.955	1.00
354_F	358_V	0.954	1.00
475_L	504_V	0.951	1.00
264_A	274_M	0.948	1.00
362_L	405_V	0.947	1.00
363_K	401_L	0.947	1.00
54_L	57_G	0.941	1.00
362_L	401_L	0.940	1.00
362_L	365_P	0.939	1.00
458_P	493_V	0.937	1.00
121_Y	124_L	0.936	1.00
443_A	450_L	0.936	1.00
450_L	489_V	0.933	1.00
315_R	340_D	0.933	1.00
423_I	551_H	0.925	1.00
388_S	392_S	0.923	1.00
78_S	92_S	0.922	1.00
240_I	247_L	0.922	1.00
364_T	368_S	0.921	1.00
248_I	260_N	0.918	1.00
247_L	260_N	0.917	1.00
44_E	48_K	0.916	1.00
230_E	234_D	0.913	1.00
482_Y	527_D	0.913	1.00
361_E	470_Q	0.913	1.00
13_V	16_M	0.913	1.00
515_E	524_Y	0.913	1.00
483_T	525_R	0.912	1.00
292_V	295_I	0.912	1.00
511_I	541_L	0.911	1.00
250_I	336_L	0.904	1.00
481_T	526_V	0.903	1.00
393_I	397_E	0.902	1.00
166_I	170_Y	0.900	1.00
357_N	522_R	0.899	1.00
465_P	469_K	0.898	1.00
509_I	565_T	0.897	1.00
149_G	152_W	0.897	1.00
427_E	458_P	0.895	1.00
225_M	228_T	0.894	1.00
431_M	435_I	0.894	1.00
80_S	88_V	0.891	1.00
187_V	198_A	0.890	1.00
430_K	465_P	0.889	1.00
42_H	45_K	0.888	1.00
368_S	393_I	0.885	0.99
73_G	77_V	0.880	0.99
190_E	198_A	0.880	0.99
228_T	232_Q	0.877	0.99
325_M	331_W	0.876	0.99
21_C	25_L	0.876	0.99
310_I	315_R	0.875	0.99
553_G	572_K	0.871	0.99
226_T	230_E	0.871	0.99
260_N	340_D	0.871	0.99
344_T	351_R	0.870	0.99
360_H	364_T	0.867	0.99
482_Y	526_V	0.866	0.99
496_R	570_T	0.864	0.99
343_E	347_L	0.863	0.99
307_R	314_R	0.863	0.99
368_S	372_F	0.862	0.99
310_I	313_E	0.860	0.99
240_I	246_G	0.859	0.99
119_K	123_G	0.858	0.99
556_D	569_V	0.857	0.99
221_D	224_E	0.852	0.99
125_S	129_E	0.852	0.99
42_H	46_E	0.851	0.99
457_D	495_P	0.850	0.99
333_G	336_L	0.850	0.99
41_E	45_K	0.848	0.99
115_T	119_K	0.846	0.99
249_M	335_V	0.846	0.99
74_A	77_V	0.846	0.99
24_G	28_Q	0.846	0.99
430_K	434_E	0.845	0.99
223_M	227_R	0.845	0.99
121_Y	139_S	0.844	0.99
26_F	30_L	0.838	0.99
302_K	305_L	0.838	0.99
362_L	404_L	0.838	0.99
120_L	123_G	0.837	0.99
255_F	278_L	0.835	0.99
71_A	75_L	0.834	0.99
185_T	189_T	0.833	0.99
52_S	55_D	0.830	0.99
364_T	371_G	0.828	0.99
260_N	267_F	0.825	0.99
370_K	402_Q	0.824	0.99
407_D	537_T	0.824	0.99
371_G	375_T	0.823	0.99
469_K	473_L	0.821	0.99
103_Q	106_V	0.820	0.99
316_Y	341_M	0.820	0.99
34_S	37_R	0.819	0.99
45_K	49_Y	0.817	0.99
470_Q	543_I	0.815	0.99
482_Y	509_I	0.814	0.99
359_S	482_Y	0.813	0.99
370_K	373_T	0.812	0.99
214_A	218_L	0.810	0.99
400_R	404_L	0.810	0.99
411_L	415_E	0.810	0.99
52_S	56_A	0.807	0.99
511_I	516_I	0.806	0.99
189_T	193_K	0.806	0.99
357_N	364_T	0.806	0.99
254_G	260_N	0.804	0.99
354_F	364_T	0.803	0.99
319_V	338_F	0.802	0.99
459_Q	500_I	0.802	0.99
518_R	524_Y	0.800	0.99
39_A	42_H	0.798	0.99
229_Q	232_Q	0.798	0.99
185_T	214_A	0.797	0.99
409_L	537_T	0.797	0.99
345_K	349_Q	0.794	0.99
19_V	23_L	0.794	0.99
496_R	499_D	0.792	0.99
83_D	86_G	0.791	0.99
154_M	157_A	0.791	0.99
356_A	359_S	0.790	0.99
419_F	467_R	0.788	0.99
509_I	559_S	0.787	0.99
49_Y	53_L	0.785	0.99
119_K	122_Y	0.784	0.99
72_G	75_L	0.783	0.99
354_F	409_L	0.783	0.99
249_M	258_L	0.783	0.99
249_M	260_N	0.782	0.99
134_G	139_S	0.782	0.99
38_K	43_I	0.781	0.99
303_C	320_D	0.781	0.99
355_V	364_T	0.778	0.99
223_M	226_T	0.776	0.99
390_F	522_R	0.776	0.99
315_R	342_T	0.775	0.99
236_L	239_V	0.773	0.99
404_L	412_S	0.771	0.99
69_K	73_G	0.769	0.99
105_L	111_G	0.769	0.99
102_V	106_V	0.767	0.99
102_V	109_H	0.766	0.99
409_L	412_S	0.765	0.99
109_H	112_I	0.764	0.99
357_N	361_E	0.764	0.99
548_I	555_I	0.763	0.99
51_A	54_L	0.763	0.99
50_L	57_G	0.762	0.98
79_A	86_G	0.761	0.98
360_H	365_P	0.761	0.98
100_Q	103_Q	0.760	0.98
467_R	471_V	0.760	0.98
240_I	249_M	0.760	0.98
196_Y	222_L	0.755	0.98
305_L	309_P	0.755	0.98
367_T	370_K	0.754	0.98
426_F	468_L	0.754	0.98
363_K	402_Q	0.753	0.98
46_E	54_L	0.752	0.98
359_S	481_T	0.752	0.98
345_K	351_R	0.752	0.98
228_T	231_M	0.751	0.98
211_L	215_M	0.750	0.98
9_F	13_V	0.748	0.98
539_L	543_I	0.743	0.98
357_N	527_D	0.742	0.98
364_T	367_T	0.742	0.98
364_T	482_Y	0.741	0.98
483_T	509_I	0.740	0.98
401_L	408_L	0.739	0.98
39_A	57_G	0.738	0.98
120_L	124_L	0.738	0.98
337_V	340_D	0.736	0.98
363_K	372_F	0.734	0.98
355_V	358_V	0.732	0.98
442_K	445_E	0.732	0.98
369_I	398_S	0.731	0.98
105_L	108_G	0.730	0.98
365_P	401_L	0.729	0.98
239_V	246_G	0.729	0.98
224_E	228_T	0.728	0.98
260_N	263_Y	0.728	0.98
323_P	333_G	0.727	0.98
491_I	504_V	0.727	0.98
98_D	101_K	0.727	0.98
401_L	409_L	0.726	0.98
116_T	121_Y	0.726	0.98
430_K	433_G	0.725	0.98
351_R	357_N	0.725	0.98
373_T	377_L	0.725	0.98
323_P	331_W	0.724	0.98
172_S	176_R	0.724	0.98
196_Y	218_L	0.723	0.98
423_I	463_G	0.722	0.98
125_S	133_T	0.721	0.98
131_E	134_G	0.721	0.98
385_E	388_S	0.721	0.98
503_E	558_T	0.721	0.98
356_A	404_L	0.720	0.98
522_R	527_D	0.717	0.98
511_I	567_F	0.715	0.98
212_G	216_N	0.712	0.98
367_T	402_Q	0.711	0.98
398_S	402_Q	0.711	0.98
194_G	218_L	0.711	0.98
362_L	372_F	0.710	0.98
513_K	517_P	0.709	0.98
357_N	362_L	0.709	0.98
12_F	19_V	0.707	0.98
78_S	82_I	0.707	0.98
401_L	410_D	0.707	0.98
421_L	551_H	0.702	0.97
280_H	284_E	0.701	0.97
503_E	569_V	0.700	0.97
369_I	373_T	0.699	0.97
359_S	365_P	0.699	0.97
127_R	134_G	0.698	0.97
184_A	212_G	0.698	0.97
362_L	366_I	0.697	0.97
105_L	109_H	0.697	0.97
353_D	361_E	0.697	0.97
355_V	366_I	0.696	0.97
421_L	464_D	0.695	0.97
360_H	474_N	0.695	0.97
23_L	26_F	0.694	0.97
153_G	157_A	0.693	0.97
79_A	91_G	0.693	0.97
355_V	367_T	0.692	0.97
180_S	215_M	0.691	0.97
189_T	217_S	0.690	0.97
431_M	463_G	0.689	0.97
71_A	74_A	0.689	0.97
291_L	295_I	0.689	0.97
344_T	347_L	0.688	0.97
88_V	91_G	0.687	0.97
35_D	38_K	0.686	0.97
66_K	69_K	0.686	0.97
247_L	337_V	0.686	0.97
229_Q	233_R	0.685	0.97
372_F	525_R	0.681	0.97
98_D	102_V	0.680	0.97
512_Q	526_V	0.680	0.97
5_R	175_S	0.680	0.97
294_D	299_E	0.679	0.97
284_E	287_E	0.678	0.97
468_L	472_F	0.678	0.97
476_V	489_V	0.678	0.97
338_F	342_T	0.674	0.97
134_G	140_A	0.674	0.97
314_R	317_F	0.672	0.97
439_L	476_V	0.672	0.97
137_L	140_A	0.671	0.97
421_L	467_R	0.670	0.97
354_F	363_K	0.668	0.97
322_V	335_V	0.665	0.96
291_L	296_F	0.665	0.96
383_D	387_L	0.665	0.96
196_Y	216_N	0.662	0.96
292_V	296_F	0.662	0.96
123_G	135_Y	0.661	0.96
381_M	387_L	0.661	0.96
116_T	125_S	0.661	0.96
355_V	363_K	0.661	0.96
235_R	258_L	0.660	0.96
234_D	238_T	0.658	0.96
433_G	437_T	0.658	0.96
523_F	539_L	0.658	0.96
32_E	36_Q	0.657	0.96
336_L	340_D	0.657	0.96
263_Y	267_F	0.656	0.96
389_E	393_I	0.655	0.96
86_G	92_S	0.655	0.96
257_N	333_G	0.653	0.96
363_K	406_Q	0.652	0.96
180_S	207_R	0.652	0.96
68_I	72_G	0.651	0.96
246_G	267_F	0.650	0.96
43_I	58_N	0.648	0.96
16_M	19_V	0.647	0.96
226_T	229_Q	0.647	0.96
122_Y	127_R	0.644	0.96
114_S	119_K	0.644	0.96
559_S	566_V	0.643	0.96
39_A	44_E	0.643	0.96
88_V	93_N	0.643	0.96
81_V	86_G	0.643	0.96
83_D	89_L	0.641	0.96
461_V	500_I	0.639	0.96
356_A	365_P	0.639	0.96
372_F	397_E	0.636	0.95
426_F	431_M	0.636	0.95
228_T	233_R	0.633	0.95
156_T	160_C	0.633	0.95
269_I	274_M	0.633	0.95
355_V	482_Y	0.633	0.95
387_L	391_L	0.632	0.95
306_L	310_I	0.631	0.95
38_K	44_E	0.630	0.95
397_E	408_L	0.630	0.95
312_I	315_R	0.629	0.95
38_K	45_K	0.627	0.95
50_L	58_N	0.627	0.95
207_R	218_L	0.627	0.95
367_T	371_G	0.627	0.95
355_V	359_S	0.626	0.95
338_F	341_M	0.626	0.95
67_I	71_A	0.625	0.95
357_N	375_T	0.625	0.95
366_I	375_T	0.625	0.95
357_N	545_K	0.624	0.95
511_I	559_S	0.623	0.95
37_R	41_E	0.622	0.95
423_I	552_E	0.622	0.95
522_R	525_R	0.622	0.95
181_I	208_S	0.622	0.95
279_Y	282_A	0.618	0.95
29_Q	33_T	0.616	0.95
305_L	310_I	0.616	0.95
295_I	321_G	0.616	0.95
133_T	137_L	0.615	0.95
294_D	297_M	0.615	0.95
256_I	276_R	0.615	0.95
363_K	409_L	0.615	0.95
125_S	135_Y	0.615	0.95
195_N	199_R	0.615	0.95
364_T	409_L	0.611	0.94
404_L	409_L	0.611	0.94
454_V	458_P	0.610	0.94
53_L	56_A	0.610	0.94
39_A	54_L	0.610	0.94
354_F	362_L	0.609	0.94
371_G	398_S	0.609	0.94
325_M	329_D	0.608	0.94
467_R	551_H	0.608	0.94
467_R	544_V	0.607	0.94
421_L	550_A	0.606	0.94
66_K	70_D	0.605	0.94
389_E	437_T	0.604	0.94
396_K	434_E	0.604	0.94
413_K	419_F	0.604	0.94
88_V	99_S	0.602	0.94
191_L	196_Y	0.602	0.94
444_D	447_G	0.601	0.94
360_H	363_K	0.601	0.94
482_Y	522_R	0.600	0.94
55_D	58_N	0.599	0.94
304_K	310_I	0.599	0.94
432_L	452_L	0.599	0.94
47_A	125_S	0.598	0.94
361_E	401_L	0.598	0.94
256_I	259_V	0.597	0.94
239_V	260_N	0.597	0.94
358_V	368_S	0.597	0.94
72_G	77_V	0.596	0.94
364_T	543_I	0.595	0.94
48_K	51_A	0.595	0.94
101_K	109_H	0.592	0.93
232_Q	237_L	0.591	0.93
362_L	543_I	0.591	0.93
138_L	141_S	0.591	0.93
522_R	526_V	0.591	0.93
227_R	231_M	0.590	0.93
429_A	456_K	0.590	0.93
316_Y	345_K	0.590	0.93
28_Q	32_E	0.590	0.93
70_D	74_A	0.590	0.93
297_M	300_T	0.589	0.93
280_H	285_H	0.586	0.93
482_Y	524_Y	0.585	0.93
411_L	522_R	0.584	0.93
307_R	316_Y	0.584	0.93
259_V	274_M	0.584	0.93
124_L	128_S	0.583	0.93
372_F	394_I	0.582	0.93
121_Y	127_R	0.582	0.93
357_N	411_L	0.582	0.93
358_V	367_T	0.581	0.93
96_S	99_S	0.581	0.93
124_L	127_R	0.581	0.93
320_D	323_P	0.580	0.93
137_L	141_S	0.579	0.93
358_V	362_L	0.579	0.93
211_L	214_A	0.579	0.93
98_D	103_Q	0.576	0.92
240_I	245_S	0.575	0.92
135_Y	139_S	0.574	0.92
524_Y	527_D	0.574	0.92
119_K	124_L	0.573	0.92
361_E	404_L	0.573	0.92
408_L	523_F	0.573	0.92
79_A	83_D	0.573	0.92
181_I	207_R	0.573	0.92
296_F	299_E	0.573	0.92
410_D	467_R	0.572	0.92
305_L	318_E	0.572	0.92
81_V	90_Y	0.572	0.92
366_I	398_S	0.571	0.92
40_E	45_K	0.571	0.92
569_V	572_K	0.571	0.92
411_L	546_H	0.571	0.92
136_V	141_S	0.568	0.92
145_D	152_W	0.568	0.92
359_S	409_L	0.568	0.92
467_R	550_A	0.568	0.92
279_Y	285_H	0.567	0.92
291_L	299_E	0.567	0.92
235_R	239_V	0.567	0.92
459_Q	495_P	0.566	0.92
343_E	348_E	0.566	0.92
411_L	482_Y	0.566	0.92
436_E	450_L	0.565	0.92
474_N	537_T	0.564	0.92
389_E	392_S	0.563	0.92
374_E	378_D	0.561	0.91
357_N	368_S	0.561	0.91
94_G	97_A	0.561	0.91
148_K	151_L	0.560	0.91
129_E	132_K	0.560	0.91
336_L	339_H	0.558	0.91
48_K	52_S	0.558	0.91
355_V	361_E	0.557	0.91
316_Y	342_T	0.555	0.91
49_Y	54_L	0.555	0.91
363_K	470_Q	0.555	0.91
292_V	299_E	0.554	0.91
354_F	525_R	0.554	0.91
398_S	411_L	0.554	0.91
356_A	539_L	0.554	0.91
180_S	211_L	0.554	0.91
548_I	554_K	0.553	0.91
135_Y	138_L	0.553	0.91
144_S	151_L	0.553	0.91
81_V	136_V	0.551	0.91
233_R	240_I	0.551	0.91
437_T	440_K	0.551	0.91
75_L	78_S	0.551	0.91
241_E	261_R	0.550	0.91
411_L	481_T	0.550	0.91
217_S	221_D	0.548	0.90
295_I	298_T	0.547	0.90
481_T	535_G	0.546	0.90
406_Q	410_D	0.546	0.90
356_A	363_K	0.546	0.90
379_G	382_E	0.545	0.90
436_E	440_K	0.545	0.90
410_D	417_Q	0.545	0.90
546_H	549_E	0.544	0.90
211_L	219_A	0.543	0.90
235_R	249_M	0.542	0.90
278_L	282_A	0.542	0.90
468_L	548_I	0.542	0.90
361_E	367_T	0.541	0.90
376_L	394_I	0.540	0.90
88_V	92_S	0.540	0.90
394_I	398_S	0.539	0.90
180_S	206_R	0.539	0.90
243_I	337_V	0.538	0.90
522_R	546_H	0.538	0.90
12_F	15_C	0.537	0.90
279_Y	284_E	0.537	0.90
122_Y	129_E	0.536	0.90
355_V	362_L	0.536	0.90
184_A	207_R	0.536	0.90
367_T	397_E	0.535	0.89
401_L	411_L	0.535	0.89
361_E	544_V	0.535	0.89
509_I	527_D	0.535	0.89
439_L	442_K	0.533	0.89
379_G	387_L	0.532	0.89
366_I	372_F	0.532	0.89
239_V	243_I	0.532	0.89
184_A	218_L	0.532	0.89
341_M	344_T	0.532	0.89
511_I	557_V	0.531	0.89
363_K	411_L	0.530	0.89
357_N	401_L	0.530	0.89
349_Q	353_D	0.530	0.89
455_P	495_P	0.529	0.89
84_T	90_Y	0.527	0.89
202_G	216_N	0.527	0.89
256_I	263_Y	0.527	0.89
432_L	502_I	0.526	0.89
491_I	502_I	0.526	0.89
528_K	535_G	0.525	0.89
116_T	124_L	0.525	0.89
251_D	333_G	0.525	0.89
266_Q	317_F	0.525	0.89
409_L	523_F	0.525	0.89
375_T	390_F	0.524	0.88
41_E	48_K	0.524	0.88
36_Q	40_E	0.524	0.88
448_I	480_L	0.521	0.88
5_R	182_E	0.521	0.88
364_T	369_I	0.521	0.88
177_Y	208_S	0.521	0.88
359_S	483_T	0.520	0.88
89_L	92_S	0.520	0.88
363_K	367_T	0.520	0.88
356_A	470_Q	0.518	0.88
358_V	400_R	0.518	0.88
69_K	72_G	0.517	0.88
243_I	335_V	0.517	0.88
405_V	409_L	0.517	0.88
233_R	239_V	0.516	0.88
408_L	411_L	0.515	0.88
363_K	397_E	0.515	0.88
226_T	233_R	0.515	0.88
80_S	137_L	0.515	0.88
459_Q	493_V	0.514	0.88
103_Q	107_S	0.514	0.88
202_G	209_D	0.513	0.87
99_S	102_V	0.512	0.87
28_Q	31_F	0.512	0.87
390_F	394_I	0.512	0.87
446_K	485_E	0.512	0.87
353_D	365_P	0.511	0.87
407_D	413_K	0.510	0.87
117_D	141_S	0.508	0.87
309_P	314_R	0.508	0.87
355_V	415_E	0.507	0.87
364_T	415_E	0.507	0.87
368_S	371_G	0.507	0.87
31_F	34_S	0.507	0.87
325_M	332_K	0.507	0.87
368_S	376_L	0.506	0.87
79_A	92_S	0.505	0.87
178_K	182_E	0.505	0.87
368_S	411_L	0.505	0.87
355_V	483_T	0.505	0.87
246_G	263_Y	0.504	0.86
259_V	267_F	0.504	0.86
239_V	244_G	0.504	0.86
409_L	481_T	0.504	0.86
525_R	535_G	0.503	0.86
361_E	397_E	0.502	0.86
382_E	387_L	0.501	0.86
101_K	104_A	0.501	0.86
268_H	312_I	0.500	0.86

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.6788	100	0.347	Contact Map
3a0rA	2	0.5579	100	0.47	Contact Map
4gczA	2	0.5976	100	0.474	Contact Map
4bixA	2	0.3955	100	0.566	Contact Map
4r3aA	1	0.5337	100	0.568	Contact Map
4ctiA	2	0.3938	100	0.596	Contact Map
3jz3A	2	0.2798	100	0.609	Contact Map
4mpcA	2	0.5268	100	0.61	Contact Map
4q20A	2	0.3972	100	0.611	Contact Map
2c2aA	2	0.3955	100	0.613	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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