GREMLIN Database
PHOR - Alkaline phosphatase synthesis sensor protein PhoR
UniProt: P23545 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 579 (553)
Sequences: 6396 (5679)
Seq/√Len: 241.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
560_E563_R4.9951.00
505_A566_V4.7261.00
190_E195_N4.6501.00
373_T394_I4.2511.00
206_R209_D3.8331.00
483_T507_S3.8211.00
453_N492_N3.4171.00
516_I557_V3.4001.00
557_V567_F3.3411.00
245_S339_H3.2611.00
451_H488_S3.2001.00
204_Y209_D3.1681.00
502_I569_V3.1361.00
251_D255_F3.1031.00
471_V547_L3.0821.00
556_D568_T3.0411.00
548_I569_V2.9441.00
490_A505_A2.9221.00
426_F463_G2.9031.00
488_S507_S2.8571.00
492_N503_E2.8451.00
545_K549_E2.7951.00
463_G551_H2.7461.00
199_R216_N2.7151.00
471_V548_I2.6961.00
492_N505_A2.5871.00
483_T487_G2.5201.00
544_V555_I2.5181.00
427_E430_K2.5061.00
233_R237_L2.5031.00
503_E566_V2.4921.00
344_T348_E2.4881.00
494_K501_Q2.4431.00
499_D570_T2.4201.00
511_I515_E2.4151.00
548_I553_G2.3841.00
451_H490_A2.3501.00
547_L551_H2.2871.00
429_A493_V2.2811.00
188_A218_L2.2691.00
482_Y525_R2.2591.00
463_G468_L2.2511.00
377_L392_S2.2281.00
506_D510_G2.2271.00
558_T566_V2.2201.00
83_D87_K2.2191.00
501_Q568_T2.1971.00
345_K348_E2.1851.00
349_Q352_K2.1851.00
559_S563_R2.1821.00
503_E568_T2.1751.00
559_S562_G2.1691.00
343_E346_K2.1681.00
348_E352_K2.1671.00
277_R281_D2.1591.00
449_S488_S2.1471.00
559_S565_T2.0911.00
479_A489_V2.0881.00
501_Q570_T2.0861.00
496_R501_Q2.0841.00
472_F502_I2.0811.00
248_I263_Y2.0781.00
494_K503_E2.0171.00
232_Q235_R2.0161.00
453_N490_A2.0121.00
215_M218_L2.0041.00
424_E465_P1.9751.00
487_G507_S1.9691.00
440_K444_D1.9381.00
261_R265_K1.9351.00
425_T462_S1.9151.00
7_R206_R1.8871.00
219_A222_L1.8631.00
246_G266_Q1.8541.00
191_L218_L1.8441.00
512_Q515_E1.8421.00
356_A361_E1.8321.00
248_I256_I1.8281.00
199_R219_A1.8121.00
483_T489_V1.8021.00
467_R470_Q1.7691.00
348_E351_R1.7611.00
262_S265_K1.7411.00
170_Y174_T1.7361.00
377_L395_L1.7151.00
134_G141_S1.7141.00
477_N481_T1.7071.00
184_A215_M1.6981.00
554_K570_T1.6941.00
236_L240_I1.6931.00
230_E233_R1.6801.00
454_V493_V1.6611.00
377_L388_S1.6351.00
47_A51_A1.6351.00
188_A215_M1.6341.00
434_E469_K1.6291.00
490_A507_S1.6171.00
305_L345_K1.6131.00
246_G338_F1.6091.00
199_R220_I1.6081.00
519_I557_V1.6071.00
511_I519_I1.6061.00
520_F555_I1.5951.00
199_R223_M1.5941.00
370_K399_E1.5851.00
278_L281_D1.5821.00
516_I559_S1.5741.00
471_V544_V1.5701.00
467_R547_L1.5611.00
197_D223_M1.5511.00
191_L219_A1.5471.00
549_E554_K1.5471.00
237_L241_E1.5461.00
512_Q561_L1.5441.00
102_V105_L1.5301.00
439_L473_L1.5281.00
464_D467_R1.5211.00
370_K398_S1.5211.00
78_S91_G1.5151.00
248_I336_L1.5081.00
51_A55_D1.5071.00
518_R521_E1.5001.00
513_K560_E1.4771.00
553_G571_L1.4711.00
472_F476_V1.4581.00
341_M345_K1.4571.00
472_F504_V1.4481.00
39_A43_I1.4451.00
402_Q406_Q1.4371.00
432_L493_V1.4321.00
104_A108_G1.4301.00
222_L225_M1.4281.00
290_Q294_D1.4211.00
427_E460_Y1.4071.00
269_I273_H1.4061.00
43_I47_A1.4001.00
548_I571_L1.4001.00
481_T527_D1.3991.00
376_L387_L1.3981.00
218_L222_L1.3921.00
359_S364_T1.3901.00
372_F390_F1.3891.00
130_G134_G1.3831.00
243_I247_L1.3771.00
432_L472_F1.3751.00
40_E44_E1.3641.00
443_A489_V1.3621.00
369_I394_I1.3611.00
468_L551_H1.3611.00
188_A211_L1.3371.00
558_T568_T1.3311.00
38_K42_H1.3231.00
270_N273_H1.3121.00
189_T210_K1.3011.00
134_G137_L1.2971.00
233_R236_L1.2931.00
222_L226_T1.2891.00
429_A454_V1.2891.00
556_D570_T1.2861.00
429_A433_G1.2861.00
403_S466_Y1.2851.00
187_V215_M1.2841.00
557_V565_T1.2821.00
347_L351_R1.2711.00
82_I88_V1.2701.00
205_I209_D1.2591.00
326_G330_E1.2561.00
471_V551_H1.2561.00
294_D298_T1.2541.00
373_T398_S1.2411.00
174_T178_K1.2411.00
25_L29_Q1.2371.00
368_S397_E1.2311.00
185_T210_K1.2291.00
177_Y180_S1.2281.00
520_F557_V1.2171.00
47_A50_L1.2161.00
520_F567_F1.2161.00
188_A214_A1.2101.00
361_E365_P1.2081.00
318_E344_T1.2061.00
187_V200_T1.2021.00
428_P502_I1.2021.00
100_Q104_A1.2011.00
134_G138_L1.1961.00
425_T460_Y1.1951.00
513_K516_I1.1811.00
398_S401_L1.1791.00
225_M229_Q1.1771.00
432_L491_I1.1681.00
439_L480_L1.1651.00
515_E526_V1.1611.00
434_E465_P1.1591.00
435_I469_K1.1501.00
493_V502_I1.1501.00
397_E400_R1.1461.00
372_F393_I1.1451.00
443_A480_L1.1411.00
240_I260_N1.1381.00
481_T525_R1.1361.00
436_E452_L1.1281.00
346_K349_Q1.1211.00
470_Q547_L1.1201.00
125_S134_G1.1191.00
175_S179_R1.1171.00
67_I70_D1.1161.00
361_E364_T1.1091.00
119_K125_S1.1091.00
499_D554_K1.1081.00
108_G111_G1.1031.00
519_I567_F1.1001.00
361_E543_I1.0981.00
200_T212_G1.0971.00
461_V571_L1.0921.00
259_V263_Y1.0911.00
354_F359_S1.0891.00
468_L569_V1.0881.00
264_A271_P1.0791.00
455_P494_K1.0791.00
358_V408_L1.0741.00
380_A387_L1.0741.00
521_E524_Y1.0731.00
250_I256_I1.0701.00
511_I565_T1.0691.00
264_A270_N1.0671.00
304_K307_R1.0651.00
447_G485_E1.0651.00
373_T395_L1.0651.00
259_V264_A1.0651.00
184_A188_A1.0571.00
376_L391_L1.0551.00
475_L569_V1.0541.00
435_I476_V1.0531.00
392_S396_K1.0511.00
433_G452_L1.0511.00
354_F357_N1.0461.00
246_G260_N1.0461.00
318_E339_H1.0461.00
41_E44_E1.0411.00
397_E409_L1.0381.00
357_N363_K1.0381.00
46_E51_A1.0361.00
438_L473_L1.0361.00
195_N198_A1.0341.00
101_K105_L1.0331.00
46_E49_Y1.0311.00
476_V491_I1.0301.00
428_P500_I1.0301.00
202_G206_R1.0291.00
232_Q236_L1.0291.00
408_L412_S1.0271.00
239_V249_M1.0271.00
527_D535_G1.0241.00
23_L27_L1.0241.00
249_M333_G1.0241.00
409_L413_K1.0221.00
347_L350_M1.0211.00
384_K387_L1.0191.00
114_S121_Y1.0171.00
216_N219_A1.0091.00
293_E297_M1.0091.00
40_E43_I1.0071.00
353_D357_N1.0021.00
29_Q32_E1.0021.00
359_S363_K1.0001.00
472_F569_V0.9991.00
260_N342_T0.9941.00
80_S91_G0.9931.00
99_S103_Q0.9901.00
240_I258_L0.9871.00
356_A362_L0.9841.00
453_N494_K0.9841.00
290_Q293_E0.9831.00
45_K48_K0.9811.00
346_K350_M0.9811.00
471_V569_V0.9791.00
261_R264_A0.9781.00
211_L218_L0.9781.00
46_E50_L0.9771.00
475_L544_V0.9771.00
38_K41_E0.9761.00
231_M235_R0.9751.00
423_I462_S0.9731.00
373_T391_L0.9701.00
50_L53_L0.9681.00
395_L399_E0.9681.00
27_L31_F0.9661.00
122_Y125_S0.9591.00
115_T121_Y0.9581.00
200_T216_N0.9571.00
475_L567_F0.9551.00
354_F358_V0.9541.00
475_L504_V0.9511.00
264_A274_M0.9481.00
362_L405_V0.9471.00
363_K401_L0.9471.00
54_L57_G0.9411.00
362_L401_L0.9401.00
362_L365_P0.9391.00
458_P493_V0.9371.00
121_Y124_L0.9361.00
443_A450_L0.9361.00
450_L489_V0.9331.00
315_R340_D0.9331.00
423_I551_H0.9251.00
388_S392_S0.9231.00
78_S92_S0.9221.00
240_I247_L0.9221.00
364_T368_S0.9211.00
248_I260_N0.9181.00
247_L260_N0.9171.00
44_E48_K0.9161.00
230_E234_D0.9131.00
482_Y527_D0.9131.00
361_E470_Q0.9131.00
13_V16_M0.9131.00
515_E524_Y0.9131.00
483_T525_R0.9121.00
292_V295_I0.9121.00
511_I541_L0.9111.00
250_I336_L0.9041.00
481_T526_V0.9031.00
393_I397_E0.9021.00
166_I170_Y0.9001.00
357_N522_R0.8991.00
465_P469_K0.8981.00
509_I565_T0.8971.00
149_G152_W0.8971.00
427_E458_P0.8951.00
225_M228_T0.8941.00
431_M435_I0.8941.00
80_S88_V0.8911.00
187_V198_A0.8901.00
430_K465_P0.8891.00
42_H45_K0.8881.00
368_S393_I0.8850.99
73_G77_V0.8800.99
190_E198_A0.8800.99
228_T232_Q0.8770.99
325_M331_W0.8760.99
21_C25_L0.8760.99
310_I315_R0.8750.99
553_G572_K0.8710.99
226_T230_E0.8710.99
260_N340_D0.8710.99
344_T351_R0.8700.99
360_H364_T0.8670.99
482_Y526_V0.8660.99
496_R570_T0.8640.99
343_E347_L0.8630.99
307_R314_R0.8630.99
368_S372_F0.8620.99
310_I313_E0.8600.99
240_I246_G0.8590.99
119_K123_G0.8580.99
556_D569_V0.8570.99
221_D224_E0.8520.99
125_S129_E0.8520.99
42_H46_E0.8510.99
457_D495_P0.8500.99
333_G336_L0.8500.99
41_E45_K0.8480.99
115_T119_K0.8460.99
249_M335_V0.8460.99
74_A77_V0.8460.99
24_G28_Q0.8460.99
430_K434_E0.8450.99
223_M227_R0.8450.99
121_Y139_S0.8440.99
26_F30_L0.8380.99
302_K305_L0.8380.99
362_L404_L0.8380.99
120_L123_G0.8370.99
255_F278_L0.8350.99
71_A75_L0.8340.99
185_T189_T0.8330.99
52_S55_D0.8300.99
364_T371_G0.8280.99
260_N267_F0.8250.99
370_K402_Q0.8240.99
407_D537_T0.8240.99
371_G375_T0.8230.99
469_K473_L0.8210.99
103_Q106_V0.8200.99
316_Y341_M0.8200.99
34_S37_R0.8190.99
45_K49_Y0.8170.99
470_Q543_I0.8150.99
482_Y509_I0.8140.99
359_S482_Y0.8130.99
370_K373_T0.8120.99
214_A218_L0.8100.99
400_R404_L0.8100.99
411_L415_E0.8100.99
52_S56_A0.8070.99
511_I516_I0.8060.99
189_T193_K0.8060.99
357_N364_T0.8060.99
254_G260_N0.8040.99
354_F364_T0.8030.99
319_V338_F0.8020.99
459_Q500_I0.8020.99
518_R524_Y0.8000.99
39_A42_H0.7980.99
229_Q232_Q0.7980.99
185_T214_A0.7970.99
409_L537_T0.7970.99
345_K349_Q0.7940.99
19_V23_L0.7940.99
496_R499_D0.7920.99
83_D86_G0.7910.99
154_M157_A0.7910.99
356_A359_S0.7900.99
419_F467_R0.7880.99
509_I559_S0.7870.99
49_Y53_L0.7850.99
119_K122_Y0.7840.99
72_G75_L0.7830.99
354_F409_L0.7830.99
249_M258_L0.7830.99
249_M260_N0.7820.99
134_G139_S0.7820.99
38_K43_I0.7810.99
303_C320_D0.7810.99
355_V364_T0.7780.99
223_M226_T0.7760.99
390_F522_R0.7760.99
315_R342_T0.7750.99
236_L239_V0.7730.99
404_L412_S0.7710.99
69_K73_G0.7690.99
105_L111_G0.7690.99
102_V106_V0.7670.99
102_V109_H0.7660.99
409_L412_S0.7650.99
109_H112_I0.7640.99
357_N361_E0.7640.99
548_I555_I0.7630.99
51_A54_L0.7630.99
50_L57_G0.7620.98
79_A86_G0.7610.98
360_H365_P0.7610.98
100_Q103_Q0.7600.98
467_R471_V0.7600.98
240_I249_M0.7600.98
196_Y222_L0.7550.98
305_L309_P0.7550.98
367_T370_K0.7540.98
426_F468_L0.7540.98
363_K402_Q0.7530.98
46_E54_L0.7520.98
359_S481_T0.7520.98
345_K351_R0.7520.98
228_T231_M0.7510.98
211_L215_M0.7500.98
9_F13_V0.7480.98
539_L543_I0.7430.98
357_N527_D0.7420.98
364_T367_T0.7420.98
364_T482_Y0.7410.98
483_T509_I0.7400.98
401_L408_L0.7390.98
39_A57_G0.7380.98
120_L124_L0.7380.98
337_V340_D0.7360.98
363_K372_F0.7340.98
355_V358_V0.7320.98
442_K445_E0.7320.98
369_I398_S0.7310.98
105_L108_G0.7300.98
365_P401_L0.7290.98
239_V246_G0.7290.98
224_E228_T0.7280.98
260_N263_Y0.7280.98
323_P333_G0.7270.98
491_I504_V0.7270.98
98_D101_K0.7270.98
401_L409_L0.7260.98
116_T121_Y0.7260.98
430_K433_G0.7250.98
351_R357_N0.7250.98
373_T377_L0.7250.98
323_P331_W0.7240.98
172_S176_R0.7240.98
196_Y218_L0.7230.98
423_I463_G0.7220.98
125_S133_T0.7210.98
131_E134_G0.7210.98
385_E388_S0.7210.98
503_E558_T0.7210.98
356_A404_L0.7200.98
522_R527_D0.7170.98
511_I567_F0.7150.98
212_G216_N0.7120.98
367_T402_Q0.7110.98
398_S402_Q0.7110.98
194_G218_L0.7110.98
362_L372_F0.7100.98
513_K517_P0.7090.98
357_N362_L0.7090.98
12_F19_V0.7070.98
78_S82_I0.7070.98
401_L410_D0.7070.98
421_L551_H0.7020.97
280_H284_E0.7010.97
503_E569_V0.7000.97
369_I373_T0.6990.97
359_S365_P0.6990.97
127_R134_G0.6980.97
184_A212_G0.6980.97
362_L366_I0.6970.97
105_L109_H0.6970.97
353_D361_E0.6970.97
355_V366_I0.6960.97
421_L464_D0.6950.97
360_H474_N0.6950.97
23_L26_F0.6940.97
153_G157_A0.6930.97
79_A91_G0.6930.97
355_V367_T0.6920.97
180_S215_M0.6910.97
189_T217_S0.6900.97
431_M463_G0.6890.97
71_A74_A0.6890.97
291_L295_I0.6890.97
344_T347_L0.6880.97
88_V91_G0.6870.97
35_D38_K0.6860.97
66_K69_K0.6860.97
247_L337_V0.6860.97
229_Q233_R0.6850.97
372_F525_R0.6810.97
98_D102_V0.6800.97
512_Q526_V0.6800.97
5_R175_S0.6800.97
294_D299_E0.6790.97
284_E287_E0.6780.97
468_L472_F0.6780.97
476_V489_V0.6780.97
338_F342_T0.6740.97
134_G140_A0.6740.97
314_R317_F0.6720.97
439_L476_V0.6720.97
137_L140_A0.6710.97
421_L467_R0.6700.97
354_F363_K0.6680.97
322_V335_V0.6650.96
291_L296_F0.6650.96
383_D387_L0.6650.96
196_Y216_N0.6620.96
292_V296_F0.6620.96
123_G135_Y0.6610.96
381_M387_L0.6610.96
116_T125_S0.6610.96
355_V363_K0.6610.96
235_R258_L0.6600.96
234_D238_T0.6580.96
433_G437_T0.6580.96
523_F539_L0.6580.96
32_E36_Q0.6570.96
336_L340_D0.6570.96
263_Y267_F0.6560.96
389_E393_I0.6550.96
86_G92_S0.6550.96
257_N333_G0.6530.96
363_K406_Q0.6520.96
180_S207_R0.6520.96
68_I72_G0.6510.96
246_G267_F0.6500.96
43_I58_N0.6480.96
16_M19_V0.6470.96
226_T229_Q0.6470.96
122_Y127_R0.6440.96
114_S119_K0.6440.96
559_S566_V0.6430.96
39_A44_E0.6430.96
88_V93_N0.6430.96
81_V86_G0.6430.96
83_D89_L0.6410.96
461_V500_I0.6390.96
356_A365_P0.6390.96
372_F397_E0.6360.95
426_F431_M0.6360.95
228_T233_R0.6330.95
156_T160_C0.6330.95
269_I274_M0.6330.95
355_V482_Y0.6330.95
387_L391_L0.6320.95
306_L310_I0.6310.95
38_K44_E0.6300.95
397_E408_L0.6300.95
312_I315_R0.6290.95
38_K45_K0.6270.95
50_L58_N0.6270.95
207_R218_L0.6270.95
367_T371_G0.6270.95
355_V359_S0.6260.95
338_F341_M0.6260.95
67_I71_A0.6250.95
357_N375_T0.6250.95
366_I375_T0.6250.95
357_N545_K0.6240.95
511_I559_S0.6230.95
37_R41_E0.6220.95
423_I552_E0.6220.95
522_R525_R0.6220.95
181_I208_S0.6220.95
279_Y282_A0.6180.95
29_Q33_T0.6160.95
305_L310_I0.6160.95
295_I321_G0.6160.95
133_T137_L0.6150.95
294_D297_M0.6150.95
256_I276_R0.6150.95
363_K409_L0.6150.95
125_S135_Y0.6150.95
195_N199_R0.6150.95
364_T409_L0.6110.94
404_L409_L0.6110.94
454_V458_P0.6100.94
53_L56_A0.6100.94
39_A54_L0.6100.94
354_F362_L0.6090.94
371_G398_S0.6090.94
325_M329_D0.6080.94
467_R551_H0.6080.94
467_R544_V0.6070.94
421_L550_A0.6060.94
66_K70_D0.6050.94
389_E437_T0.6040.94
396_K434_E0.6040.94
413_K419_F0.6040.94
88_V99_S0.6020.94
191_L196_Y0.6020.94
444_D447_G0.6010.94
360_H363_K0.6010.94
482_Y522_R0.6000.94
55_D58_N0.5990.94
304_K310_I0.5990.94
432_L452_L0.5990.94
47_A125_S0.5980.94
361_E401_L0.5980.94
256_I259_V0.5970.94
239_V260_N0.5970.94
358_V368_S0.5970.94
72_G77_V0.5960.94
364_T543_I0.5950.94
48_K51_A0.5950.94
101_K109_H0.5920.93
232_Q237_L0.5910.93
362_L543_I0.5910.93
138_L141_S0.5910.93
522_R526_V0.5910.93
227_R231_M0.5900.93
429_A456_K0.5900.93
316_Y345_K0.5900.93
28_Q32_E0.5900.93
70_D74_A0.5900.93
297_M300_T0.5890.93
280_H285_H0.5860.93
482_Y524_Y0.5850.93
411_L522_R0.5840.93
307_R316_Y0.5840.93
259_V274_M0.5840.93
124_L128_S0.5830.93
372_F394_I0.5820.93
121_Y127_R0.5820.93
357_N411_L0.5820.93
358_V367_T0.5810.93
96_S99_S0.5810.93
124_L127_R0.5810.93
320_D323_P0.5800.93
137_L141_S0.5790.93
358_V362_L0.5790.93
211_L214_A0.5790.93
98_D103_Q0.5760.92
240_I245_S0.5750.92
135_Y139_S0.5740.92
524_Y527_D0.5740.92
119_K124_L0.5730.92
361_E404_L0.5730.92
408_L523_F0.5730.92
79_A83_D0.5730.92
181_I207_R0.5730.92
296_F299_E0.5730.92
410_D467_R0.5720.92
305_L318_E0.5720.92
81_V90_Y0.5720.92
366_I398_S0.5710.92
40_E45_K0.5710.92
569_V572_K0.5710.92
411_L546_H0.5710.92
136_V141_S0.5680.92
145_D152_W0.5680.92
359_S409_L0.5680.92
467_R550_A0.5680.92
279_Y285_H0.5670.92
291_L299_E0.5670.92
235_R239_V0.5670.92
459_Q495_P0.5660.92
343_E348_E0.5660.92
411_L482_Y0.5660.92
436_E450_L0.5650.92
474_N537_T0.5640.92
389_E392_S0.5630.92
374_E378_D0.5610.91
357_N368_S0.5610.91
94_G97_A0.5610.91
148_K151_L0.5600.91
129_E132_K0.5600.91
336_L339_H0.5580.91
48_K52_S0.5580.91
355_V361_E0.5570.91
316_Y342_T0.5550.91
49_Y54_L0.5550.91
363_K470_Q0.5550.91
292_V299_E0.5540.91
354_F525_R0.5540.91
398_S411_L0.5540.91
356_A539_L0.5540.91
180_S211_L0.5540.91
548_I554_K0.5530.91
135_Y138_L0.5530.91
144_S151_L0.5530.91
81_V136_V0.5510.91
233_R240_I0.5510.91
437_T440_K0.5510.91
75_L78_S0.5510.91
241_E261_R0.5500.91
411_L481_T0.5500.91
217_S221_D0.5480.90
295_I298_T0.5470.90
481_T535_G0.5460.90
406_Q410_D0.5460.90
356_A363_K0.5460.90
379_G382_E0.5450.90
436_E440_K0.5450.90
410_D417_Q0.5450.90
546_H549_E0.5440.90
211_L219_A0.5430.90
235_R249_M0.5420.90
278_L282_A0.5420.90
468_L548_I0.5420.90
361_E367_T0.5410.90
376_L394_I0.5400.90
88_V92_S0.5400.90
394_I398_S0.5390.90
180_S206_R0.5390.90
243_I337_V0.5380.90
522_R546_H0.5380.90
12_F15_C0.5370.90
279_Y284_E0.5370.90
122_Y129_E0.5360.90
355_V362_L0.5360.90
184_A207_R0.5360.90
367_T397_E0.5350.89
401_L411_L0.5350.89
361_E544_V0.5350.89
509_I527_D0.5350.89
439_L442_K0.5330.89
379_G387_L0.5320.89
366_I372_F0.5320.89
239_V243_I0.5320.89
184_A218_L0.5320.89
341_M344_T0.5320.89
511_I557_V0.5310.89
363_K411_L0.5300.89
357_N401_L0.5300.89
349_Q353_D0.5300.89
455_P495_P0.5290.89
84_T90_Y0.5270.89
202_G216_N0.5270.89
256_I263_Y0.5270.89
432_L502_I0.5260.89
491_I502_I0.5260.89
528_K535_G0.5250.89
116_T124_L0.5250.89
251_D333_G0.5250.89
266_Q317_F0.5250.89
409_L523_F0.5250.89
375_T390_F0.5240.88
41_E48_K0.5240.88
36_Q40_E0.5240.88
448_I480_L0.5210.88
5_R182_E0.5210.88
364_T369_I0.5210.88
177_Y208_S0.5210.88
359_S483_T0.5200.88
89_L92_S0.5200.88
363_K367_T0.5200.88
356_A470_Q0.5180.88
358_V400_R0.5180.88
69_K72_G0.5170.88
243_I335_V0.5170.88
405_V409_L0.5170.88
233_R239_V0.5160.88
408_L411_L0.5150.88
363_K397_E0.5150.88
226_T233_R0.5150.88
80_S137_L0.5150.88
459_Q493_V0.5140.88
103_Q107_S0.5140.88
202_G209_D0.5130.87
99_S102_V0.5120.87
28_Q31_F0.5120.87
390_F394_I0.5120.87
446_K485_E0.5120.87
353_D365_P0.5110.87
407_D413_K0.5100.87
117_D141_S0.5080.87
309_P314_R0.5080.87
355_V415_E0.5070.87
364_T415_E0.5070.87
368_S371_G0.5070.87
31_F34_S0.5070.87
325_M332_K0.5070.87
368_S376_L0.5060.87
79_A92_S0.5050.87
178_K182_E0.5050.87
368_S411_L0.5050.87
355_V483_T0.5050.87
246_G263_Y0.5040.86
259_V267_F0.5040.86
239_V244_G0.5040.86
409_L481_T0.5040.86
525_R535_G0.5030.86
361_E397_E0.5020.86
382_E387_L0.5010.86
101_K104_A0.5010.86
268_H312_I0.5000.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4i5sA 2 0.6788 100 0.347 Contact Map
3a0rA 2 0.5579 100 0.47 Contact Map
4gczA 2 0.5976 100 0.474 Contact Map
4bixA 2 0.3955 100 0.566 Contact Map
4r3aA 1 0.5337 100 0.568 Contact Map
4ctiA 2 0.3938 100 0.596 Contact Map
3jz3A 2 0.2798 100 0.609 Contact Map
4mpcA 2 0.5268 100 0.61 Contact Map
4q20A 2 0.3972 100 0.611 Contact Map
2c2aA 2 0.3955 100 0.613 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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