GREMLIN Database
ADDB - ATP-dependent helicase/deoxyribonuclease subunit B
UniProt: P23477 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 1166 (926)
Sequences: 2985 (2498)
Seq/√Len: 82.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
609_A667_V7.2941.00
34_P203_A7.1311.00
327_I607_L6.7951.00
368_I588_V5.8201.00
330_E333_A4.7081.00
331_I345_V4.3281.00
344_D602_S4.2691.00
330_E666_Y3.9801.00
893_V896_V3.9581.00
330_E605_F3.7941.00
175_S178_D3.7831.00
810_G813_L3.6121.00
141_R166_S3.5191.00
341_R586_D3.5051.00
171_Q174_K3.4531.00
775_L779_V3.4471.00
340_Y603_C3.3651.00
175_S179_Q3.3581.00
606_V667_V3.2231.00
350_R650_E3.1691.00
605_F666_Y3.1671.00
347_I363_F3.1521.00
986_L1004_A3.1441.00
852_T855_Q3.1341.00
99_L175_S3.1211.00
328_A366_Y3.0671.00
383_L540_A3.0561.00
687_R691_L3.0481.00
602_S662_S3.0031.00
600_G662_S3.0021.00
813_L817_Q2.9901.00
591_G601_T2.9881.00
684_I687_R2.9531.00
487_Q511_E2.9351.00
233_F236_T2.8861.00
970_D973_E2.8121.00
257_K291_A2.7101.00
69_S186_Y2.7071.00
412_L415_L2.6981.00
141_R170_Q2.6811.00
106_E171_Q2.6681.00
329_R366_Y2.6621.00
334_L666_Y2.6591.00
813_L816_R2.6341.00
251_L255_T2.6061.00
507_R511_E2.6051.00
815_E818_F2.5741.00
24_D28_R2.5561.00
25_E204_H2.5481.00
20_N24_D2.5261.00
812_H815_E2.5251.00
688_L691_L2.5051.00
254_M258_T2.4881.00
195_P219_R2.4851.00
892_I896_V2.4401.00
334_L605_F2.4341.00
896_V899_I2.4341.00
46_L50_E2.4271.00
299_A302_A2.4241.00
363_F370_Y2.4121.00
789_Q940_V2.4111.00
335_V342_Y2.3851.00
332_H336_R2.3561.00
602_S663_D2.3471.00
683_M687_R2.3391.00
252_F255_T2.3271.00
993_S998_G2.2951.00
425_Q477_T2.2851.00
87_L180_Y2.2701.00
331_I605_F2.2431.00
776_E779_V2.2251.00
26_L55_P2.2011.00
334_L603_C2.1841.00
325_E362_V2.1671.00
343_K586_D2.1641.00
205_I224_L2.1621.00
686_K690_E2.1591.00
948_K999_M2.1581.00
399_R402_A2.1441.00
387_I544_V2.1121.00
20_N54_T2.1101.00
684_I691_L2.0821.00
333_A337_E2.0781.00
198_E201_K2.0371.00
323_E668_S2.0241.00
834_L1009_F2.0211.00
502_A565_F2.0151.00
779_V784_Y2.0091.00
255_T259_Y2.0001.00
687_R694_H2.0001.00
687_R690_E1.9991.00
824_P828_Q1.9841.00
513_D516_L1.9801.00
778_S781_R1.9791.00
774_Q779_V1.9651.00
987_D991_T1.9611.00
814_K817_Q1.9581.00
830_F964_S1.9581.00
23_Q54_T1.9521.00
355_Y608_G1.9341.00
75_V190_L1.9291.00
771_E779_V1.9251.00
390_S508_Y1.9231.00
1008_Y1011_I1.9221.00
812_H817_Q1.9131.00
778_S782_Q1.9031.00
325_E366_Y1.8961.00
606_V609_A1.8891.00
16_K20_N1.8881.00
328_A362_V1.8871.00
181_L186_Y1.8751.00
416_N425_Q1.8741.00
946_V989_S1.8681.00
651_H687_R1.8661.00
774_Q778_S1.8661.00
334_L345_V1.8641.00
176_L185_D1.8551.00
777_R780_S1.8381.00
813_L818_F1.8381.00
350_R653_L1.8361.00
859_F862_D1.8231.00
370_Y590_V1.8221.00
947_D960_V1.8181.00
92_V172_M1.8181.00
102_E175_S1.8051.00
275_Y279_S1.8011.00
103_H171_Q1.8001.00
324_L359_V1.7981.00
29_A32_G1.7911.00
270_N273_I1.7901.00
332_H366_Y1.7901.00
678_T681_P1.7801.00
41_D69_S1.7701.00
885_V888_K1.7661.00
603_C666_Y1.7581.00
684_I694_H1.7561.00
519_D538_Q1.7521.00
233_F238_D1.7421.00
814_K818_F1.7321.00
209_G597_R1.7271.00
479_D483_P1.7141.00
335_V345_V1.6981.00
945_R960_V1.6911.00
775_L778_S1.6871.00
389_S405_R1.6761.00
780_S783_L1.6601.00
390_S406_C1.6591.00
327_I668_S1.6551.00
195_P223_Q1.6551.00
85_P91_G1.6421.00
949_A1002_T1.6331.00
332_H342_Y1.6331.00
689_E693_P1.6301.00
88_T550_E1.6171.00
278_L281_T1.6101.00
19_I51_L1.6101.00
775_L781_R1.6071.00
684_I690_E1.6011.00
297_Y300_R1.5951.00
688_L692_F1.5911.00
499_Q503_E1.5881.00
812_H818_F1.5871.00
248_E252_F1.5861.00
252_F256_G1.5821.00
886_K893_V1.5791.00
905_K949_A1.5761.00
284_H658_F1.5701.00
548_L565_F1.5681.00
277_E280_G1.5661.00
102_E171_Q1.5561.00
304_P307_E1.5541.00
743_W746_T1.5531.00
787_R790_G1.5521.00
252_F258_T1.5501.00
603_C664_R1.5451.00
780_S784_Y1.5421.00
688_L694_H1.5340.99
878_S882_H1.5310.99
136_E139_D1.5310.99
728_S731_R1.5220.99
777_R781_R1.5180.99
686_K691_L1.5130.99
167_I170_Q1.5120.99
691_L694_H1.5120.99
719_K731_R1.5010.99
917_G942_R1.5000.99
723_Q731_R1.5000.99
327_I605_F1.4990.99
363_F590_V1.4910.99
313_T664_R1.4790.99
685_V688_L1.4780.99
807_A815_E1.4750.99
687_R695_H1.4740.99
95_L175_S1.4690.99
905_K909_F1.4660.99
326_G668_S1.4630.99
862_D866_R1.4610.99
330_E334_L1.4540.99
362_V366_Y1.4540.99
779_V783_L1.4490.99
575_S578_F1.4480.99
779_V782_Q1.4440.99
809_H815_E1.4440.99
656_M659_S1.4430.99
171_Q175_S1.4420.99
913_G916_L1.4400.99
209_G217_E1.4390.99
716_V722_A1.4360.99
121_A125_R1.4360.99
746_T749_V1.4340.99
832_S836_L1.4290.99
359_V590_V1.4270.99
38_L221_L1.4220.99
324_L607_L1.4190.99
771_E778_S1.4190.99
1006_V1010_H1.4160.99
684_I688_L1.4150.99
572_G576_L1.4150.99
407_V415_L1.4140.99
210_F213_F1.4090.99
174_K178_D1.4070.99
300_R303_I1.3960.99
720_S730_L1.3910.99
74_R78_H1.3870.99
64_Q74_R1.3870.99
974_V1008_Y1.3860.99
806_F812_H1.3850.99
471_E475_N1.3790.99
69_S182_H1.3660.99
69_S76_L1.3630.99
475_N478_R1.3620.99
614_L650_E1.3620.99
371_F587_Q1.3610.99
373_D595_L1.3580.99
573_A576_L1.3550.99
758_Q762_L1.3540.99
559_E563_D1.3470.99
79_T82_M1.3460.99
393_V406_C1.3440.99
694_H697_E1.3440.99
327_I359_V1.3420.99
331_I342_Y1.3410.99
727_A731_R1.3400.99
806_F813_L1.3370.99
349_A356_K1.3360.99
775_L784_Y1.3340.99
807_A813_L1.3280.99
693_P697_E1.3270.99
725_F728_S1.3250.99
362_V365_D1.3230.98
294_E299_A1.3230.98
139_D142_R1.3220.98
810_G815_E1.3200.98
335_V340_Y1.3150.98
593_M614_L1.3140.98
349_A590_V1.3140.98
948_K957_L1.3080.98
137_P166_S1.3060.98
234_S238_D1.3050.98
630_E634_T1.3050.98
267_K272_D1.3000.98
949_A958_R1.2980.98
69_S214_T1.2970.98
544_V548_L1.2960.98
687_R697_E1.2950.98
688_L703_E1.2940.98
811_L814_K1.2920.98
810_G818_F1.2880.98
722_A725_F1.2840.98
407_V481_I1.2840.98
1005_G1008_Y1.2820.98
392_D570_E1.2810.98
688_L705_E1.2790.98
724_S727_A1.2770.98
173_E189_L1.2760.98
471_E474_L1.2760.98
721_V725_F1.2720.98
778_S784_Y1.2720.98
806_F809_H1.2670.98
561_S564_L1.2660.98
145_E149_A1.2660.98
210_F218_F1.2660.98
137_P170_Q1.2660.98
239_K656_M1.2640.98
236_T239_K1.2570.98
688_L695_H1.2570.98
235_L252_F1.2550.98
69_S181_L1.2540.98
774_Q777_R1.2540.98
230_H236_T1.2530.98
779_V786_E1.2530.98
719_K730_L1.2500.98
24_D27_R1.2470.98
832_S835_K1.2470.98
746_T750_L1.2460.98
835_K839_D1.2460.98
593_M609_A1.2410.98
702_N705_E1.2340.98
607_L668_S1.2270.98
811_L815_E1.2270.98
739_I742_V1.2260.98
727_A730_L1.2260.98
559_E562_L1.2250.97
887_E890_Q1.2250.97
686_K695_H1.2240.97
742_V746_T1.2240.97
947_D958_R1.2230.97
792_V796_E1.2230.97
775_L780_S1.2220.97
626_D630_E1.2220.97
959_I989_S1.2190.97
325_E365_D1.2170.97
809_H812_H1.2130.97
720_S723_Q1.2080.97
774_Q781_R1.2070.97
170_Q174_K1.2060.97
858_L862_D1.2060.97
629_R632_L1.1990.97
412_L484_P1.1980.97
255_T258_T1.1900.97
99_L103_H1.1840.97
385_E389_S1.1840.97
236_T241_S1.1830.97
683_M686_K1.1810.97
342_Y369_P1.1800.97
356_K590_V1.1790.97
807_A810_G1.1790.97
569_I572_G1.1780.97
739_I743_W1.1760.97
720_S727_A1.1760.97
277_E281_T1.1740.97
39_V597_R1.1700.97
287_T290_L1.1690.97
805_H818_F1.1670.97
972_A976_Y1.1650.97
658_F665_L1.1630.97
774_Q780_S1.1570.96
252_F259_Y1.1510.96
949_A952_S1.1500.96
291_A297_Y1.1490.96
853_K857_E1.1490.96
893_V899_I1.1480.96
217_E597_R1.1470.96
723_Q726_T1.1460.96
631_W634_T1.1460.96
500_E503_E1.1460.96
689_E694_H1.1450.96
744_W747_Y1.1450.96
886_K890_Q1.1320.96
906_A909_F1.1290.96
604_T660_S1.1270.96
294_E297_Y1.1260.96
809_H818_F1.1250.96
776_E781_R1.1230.96
278_L282_E1.1190.96
806_F814_K1.1180.96
249_L252_F1.1150.96
235_L238_D1.1140.96
329_R333_A1.1120.96
693_P696_K1.1100.96
860_S886_K1.1080.95
345_V605_F1.1010.95
562_L565_F1.1010.95
687_R705_E1.0960.95
715_Y719_K1.0960.95
781_R784_Y1.0940.95
251_L259_Y1.0940.95
886_K896_V1.0900.95
107_F110_Y1.0880.95
718_N722_A1.0880.95
441_D444_T1.0880.95
509_L541_W1.0860.95
791_S796_E1.0860.95
333_A338_K1.0850.95
191_A219_R1.0850.95
1003_P1006_V1.0830.95
816_R819_F1.0770.95
952_S958_R1.0750.95
488_L511_E1.0710.95
130_F133_Y1.0680.94
976_Y979_A1.0660.94
723_Q727_A1.0640.94
86_F186_Y1.0630.94
84_R181_L1.0630.94
551_F564_L1.0610.94
813_L819_F1.0600.94
519_D523_Q1.0580.94
856_C886_K1.0570.94
810_G814_K1.0570.94
697_E703_E1.0560.94
239_K594_D1.0560.94
341_R344_D1.0550.94
495_A499_Q1.0530.94
793_S796_E1.0520.94
248_E255_T1.0520.94
683_M688_L1.0500.94
949_A1003_P1.0480.94
886_K892_I1.0470.94
958_R1005_G1.0470.94
806_F815_E1.0470.94
488_L508_Y1.0440.94
49_Y53_K1.0420.94
8_G209_G1.0400.94
95_L99_L1.0400.94
578_F583_P1.0400.94
138_E142_R1.0360.94
918_F941_G1.0350.93
805_H815_E1.0350.93
606_V657_A1.0350.93
204_H230_H1.0310.93
8_G597_R1.0310.93
777_R784_Y1.0300.93
142_R145_E1.0300.93
690_E693_P1.0270.93
716_V721_V1.0270.93
725_F731_R1.0250.93
805_H812_H1.0230.93
564_L568_M1.0220.93
502_A548_L1.0220.93
69_S187_L1.0200.93
694_H698_R1.0200.93
743_W747_Y1.0200.93
701_T705_E1.0190.93
654_I658_F1.0190.93
1007_L1010_H1.0160.93
721_V730_L1.0140.93
815_E819_F1.0140.93
892_I899_I1.0130.93
126_M165_L1.0130.93
990_I1000_R1.0110.93
714_M717_V1.0110.93
76_L193_H1.0100.93
96_L168_L1.0100.93
471_E478_R1.0090.93
691_L697_E1.0080.93
173_E177_A1.0040.92
748_N751_M1.0040.92
277_E282_E1.0000.92
809_H814_K1.0000.92
757_L760_K0.9940.92
233_F237_A0.9930.92
18_I206_Y0.9920.92
773_K779_V0.9910.92
683_M694_H0.9870.92
480_W484_P0.9860.92
292_H296_Q0.9860.92
722_A727_A0.9850.92
104_K123_V0.9820.92
239_K348_L0.9820.92
597_R655_Y0.9820.92
181_L189_L0.9810.92
687_R693_P0.9800.91
691_L695_H0.9800.91
75_V224_L0.9790.91
277_E312_L0.9780.91
558_D564_L0.9780.91
481_I485_L0.9780.91
323_E608_G0.9770.91
747_Y751_M0.9760.91
726_T731_R0.9760.91
810_G817_Q0.9740.91
18_I234_S0.9740.91
919_G938_E0.9730.91
604_T661_P0.9700.91
235_L241_S0.9690.91
347_I389_S0.9690.91
300_R304_P0.9660.91
211_Y239_K0.9650.91
890_Q894_T0.9650.91
239_K659_S0.9630.91
857_E861_Y0.9620.91
655_Y659_S0.9620.91
324_L328_A0.9600.91
683_M696_K0.9600.91
918_F988_L0.9560.90
330_E664_R0.9560.90
806_F817_Q0.9560.90
8_G234_S0.9550.90
217_E594_D0.9550.90
273_I277_E0.9540.90
726_T730_L0.9520.90
741_D745_S0.9510.90
160_E163_H0.9500.90
313_T316_Q0.9500.90
242_Y597_R0.9490.90
89_S92_V0.9490.90
597_R656_M0.9480.90
198_E202_G0.9470.90
240_P247_H0.9450.90
248_E251_L0.9440.90
11_G14_K0.9440.90
392_D402_A0.9430.90
360_K364_A0.9410.90
773_K778_S0.9410.90
212_Q597_R0.9410.90
96_L128_T0.9410.90
473_M477_T0.9390.90
801_C804_S0.9380.90
190_L220_V0.9340.89
943_I946_V0.9310.89
22_I51_L0.9300.89
8_G242_Y0.9280.89
768_F771_E0.9270.89
692_F695_H0.9260.89
714_M726_T0.9250.89
219_R222_E0.9240.89
310_E313_T0.9240.89
697_E701_T0.9230.89
886_K899_I0.9210.89
237_A252_F0.9210.89
812_H819_F0.9210.89
689_E695_H0.9170.89
144_A166_S0.9160.88
806_F810_G0.9160.88
693_P703_E0.9140.88
484_P488_L0.9110.88
348_L604_T0.9110.88
334_L340_Y0.9090.88
211_Y656_M0.9080.88
48_E52_A0.9070.88
501_K505_L0.9060.88
684_I693_P0.9060.88
234_S242_Y0.9050.88
340_Y345_V0.9050.88
230_H233_F0.9050.88
656_M660_S0.9040.88
300_R305_Y0.9040.88
715_Y718_N0.9030.88
616_A643_G0.9000.88
617_R620_E0.9000.88
169_Y173_E0.8990.88
335_V341_R0.8990.88
441_D445_K0.8980.87
237_A240_P0.8960.87
212_Q656_M0.8920.87
8_G46_L0.8920.87
552_V556_G0.8920.87
351_Q357_D0.8910.87
667_V688_L0.8910.87
91_G94_M0.8890.87
292_H297_Y0.8880.87
986_L990_I0.8870.87
716_V730_L0.8870.87
515_P519_D0.8850.87
235_L239_K0.8850.87
594_D597_R0.8850.87
723_Q730_L0.8850.87
918_F943_I0.8820.87
236_T240_P0.8820.87
172_M182_H0.8800.86
373_D795_M0.8790.86
68_F213_F0.8790.86
605_F668_S0.8760.86
272_D600_G0.8760.86
1006_V1011_I0.8750.86
731_R734_T0.8740.86
103_H106_E0.8720.86
310_E314_V0.8700.86
721_V731_R0.8690.86
192_E196_L0.8690.86
789_Q792_V0.8680.86
598_M660_S0.8670.86
701_T704_P0.8640.85
745_S749_V0.8640.85
916_L946_V0.8640.85
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543_A576_L0.5740.56
801_C811_L0.5740.56
569_I575_S0.5740.56
487_Q507_R0.5730.56
882_H886_K0.5730.56
293_L299_A0.5730.56
275_Y306_A0.5730.56
838_S914_L0.5720.56
435_A438_I0.5720.56
328_A332_H0.5720.56
883_Y894_T0.5710.56
313_T666_Y0.5710.56
688_L700_L0.5710.56
627_D630_E0.5710.56
68_F207_V0.5710.56
864_V881_R0.5710.56
236_T652_F0.5700.55
8_G235_L0.5700.55
63_A185_D0.5700.55
986_L1006_V0.5700.55
207_V661_P0.5690.55
271_L602_S0.5690.55
684_I689_E0.5680.55
381_H605_F0.5680.55
249_L277_E0.5680.55
265_K269_L0.5680.55
271_L274_T0.5680.55
256_G259_Y0.5670.55
11_G15_T0.5670.55
715_Y722_A0.5660.55
209_G593_M0.5660.55
391_L562_L0.5660.55
35_I659_S0.5660.55
721_V724_S0.5650.55
403_V444_T0.5640.55
236_T656_M0.5630.55
594_D653_L0.5630.55
50_E599_Y0.5630.55
669_Y685_V0.5620.54
412_L478_R0.5620.54
212_Q348_L0.5620.54
39_V594_D0.5620.54
212_Q241_S0.5610.54
560_I564_L0.5610.54
230_H237_A0.5610.54
975_Y979_A0.5610.54
23_Q26_L0.5610.54
681_P684_I0.5600.54
744_W750_L0.5600.54
99_L171_Q0.5600.54
893_V897_S0.5600.54
247_H397_N0.5600.54
10_S236_T0.5590.54
39_V212_Q0.5590.54
290_L295_A0.5590.54
387_I541_W0.5580.54
22_I37_F0.5580.54
305_Y308_K0.5580.54
803_F813_L0.5580.54
212_Q594_D0.5570.54
235_L649_D0.5560.54
96_L124_E0.5560.54
700_L705_E0.5560.54
183_S187_L0.5550.54
50_E348_L0.5550.54
438_I441_D0.5550.54
356_K359_V0.5550.54
564_L567_Q0.5550.54
210_F217_E0.5540.53
374_G653_L0.5540.53
750_L757_L0.5540.53
69_S72_A0.5530.53
67_S234_S0.5530.53
8_G239_K0.5520.53
520_Q523_Q0.5520.53
476_D480_W0.5520.53
468_I472_N0.5510.53
889_L893_V0.5510.53
837_I982_M0.5510.53
592_N598_M0.5510.53
715_Y720_S0.5510.53
330_E668_S0.5500.53
36_I205_I0.5500.53
687_R704_P0.5500.53
440_G444_T0.5500.53
137_P141_R0.5490.53
328_A363_F0.5490.53
349_A942_R0.5480.53
36_I75_V0.5480.53
114_S120_T0.5480.53
690_E694_H0.5470.52
389_S775_L0.5470.52
854_E950_E0.5470.52
209_G234_S0.5460.52
560_I590_V0.5460.52
295_A300_R0.5460.52
582_P587_Q0.5460.52
688_L696_K0.5460.52
565_F572_G0.5450.52
693_P701_T0.5450.52
316_Q322_A0.5450.52
85_P552_V0.5450.52
562_L568_M0.5430.52
982_M1004_A0.5430.52
166_S170_Q0.5420.52
207_V221_L0.5420.52
714_M723_Q0.5410.52
185_D655_Y0.5410.52
312_L317_A0.5410.52
8_G13_G0.5410.52
317_A322_A0.5400.52
958_R1003_P0.5400.52
949_A1005_G0.5400.52
348_L597_R0.5400.52
217_E598_M0.5390.51
140_I166_S0.5390.51
834_L893_V0.5390.51
853_K887_E0.5380.51
150_S154_G0.5380.51
795_M918_F0.5380.51
627_D632_L0.5380.51
694_H700_L0.5380.51
289_E298_E0.5380.51
272_D282_E0.5370.51
46_L599_Y0.5370.51
468_I471_E0.5370.51
715_Y721_V0.5370.51
331_I336_R0.5360.51
234_S240_P0.5360.51
10_S282_E0.5360.51
880_N883_Y0.5360.51
543_A546_Q0.5360.51
809_H816_R0.5360.51
22_I206_Y0.5350.51
611_D683_M0.5350.51
241_S594_D0.5340.51
125_R128_T0.5340.51
416_N876_L0.5340.51
344_D663_D0.5340.51
728_S732_L0.5330.51
691_L696_K0.5330.51
993_S999_M0.5330.51
763_F768_F0.5320.51
237_A253_R0.5320.51
779_V785_G0.5320.51
691_L702_N0.5320.51
235_L656_M0.5320.51
285_T288_P0.5320.51
371_F583_P0.5310.50
394_L974_V0.5300.50
484_P511_E0.5300.50
311_A316_Q0.5300.50
736_E743_W0.5300.50
11_G39_V0.5300.50
253_R257_K0.5290.50
472_N475_N0.5290.50
100_I168_L0.5280.50
39_V599_Y0.5270.50
43_M660_S0.5270.50
240_P243_E0.5270.50
729_Q735_R0.5270.50
209_G659_S0.5260.50
737_Y742_V0.5260.50
236_T267_K0.5250.50
389_S392_D0.5250.50
594_D660_S0.5250.50
630_E633_K0.5240.49
130_F165_L0.5240.49
838_S841_L0.5230.49
789_Q938_E0.5220.49
242_Y245_E0.5220.49
179_Q792_V0.5220.49
26_L63_A0.5220.49
242_Y659_S0.5220.49
723_Q735_R0.5220.49
50_E600_G0.5220.49
830_F987_D0.5210.49
810_G816_R0.5210.49
509_L515_P0.5210.49
765_S771_E0.5200.49
451_Y472_N0.5190.49
835_K914_L0.5190.49
117_S121_A0.5180.49
212_Q235_L0.5180.49
129_E133_Y0.5180.49
397_N489_Q0.5180.49
719_K727_A0.5170.49
341_R490_K0.5170.49
562_L577_T0.5170.49
183_S239_K0.5170.49
361_E365_D0.5170.49
597_R659_S0.5160.48
211_Y241_S0.5160.48
433_C436_Y0.5160.48
41_D45_F0.5160.48
558_D562_L0.5160.48
969_L1008_Y0.5160.48
212_Q655_Y0.5160.48
187_L220_V0.5160.48
293_L296_Q0.5150.48
616_A620_E0.5140.48
497_T500_E0.5140.48
632_L638_E0.5140.48
390_S895_R0.5140.48
239_K597_R0.5130.48
119_F937_M0.5130.48
371_F582_P0.5130.48
759_S766_L0.5130.48
415_L478_R0.5130.48
256_G264_Q0.5120.48
495_A507_R0.5110.48
211_Y599_Y0.5110.48
839_D912_I0.5110.48
837_I893_V0.5110.48
10_S660_S0.5100.48
312_L490_K0.5100.48
242_Y599_Y0.5100.48
729_Q732_L0.5090.48
127_L134_C0.5090.48
14_K208_D0.5080.47
684_I697_E0.5080.47
804_S814_K0.5080.47
360_K370_Y0.5070.47
313_T603_C0.5070.47
543_A547_L0.5070.47
243_E627_D0.5060.47
67_S212_Q0.5060.47
348_L657_A0.5060.47
561_S568_M0.5060.47
89_S128_T0.5060.47
244_R251_L0.5060.47
793_S797_T0.5050.47
182_H185_D0.5050.47
597_R652_F0.5050.47
239_K600_G0.5040.47
616_A646_R0.5040.47
43_M656_M0.5040.47
200_I203_A0.5040.47
272_D656_M0.5040.47
8_G655_Y0.5030.47
596_S660_S0.5020.47
1001_A1005_G0.5020.47
75_V701_T0.5020.47
770_N776_E0.5020.47
290_L297_Y0.5010.46
521_E537_H0.5010.46
861_Y865_E0.5000.46
751_M757_L0.5000.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3u4qA 1 0.7564 100 0.521 Contact Map
1w36B 1 0.7642 100 0.565 Contact Map
1pjrA 1 0.5 100 0.612 Contact Map
4c2tA 1 0.524 100 0.614 Contact Map
1uaaA 2 0.5206 100 0.621 Contact Map
4c2uA 1 0.5283 100 0.633 Contact Map
3lfuA 1 0.512 100 0.633 Contact Map
1w36C 1 0.837 100 0.729 Contact Map
4pj3A 1 0.4091 100 0.835 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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