ADDB - BACSU - GREMLIN Contacts

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ADDB - ATP-dependent helicase/deoxyribonuclease subunit B

UniProt:	P23477	Sequences: MGAEFLVGRSGSGKTKLIINSIQDELRRAPFGKPIIFLVPDQMTFLMEYELAKTPDMGGMIRAQVFSFSRLAWRVLQHTGGMSRPFLTSTGVQMLLRKLIEEHKQEFKVYQKASDKSGFTAQVERMLTEFKRYCLEPEDIRRMAESGTASEYRGERVLSEKLHDLSILYQQMEKSLADQYLHSEDYLTLLAEHIPLAEDIKGAHIYVDGFYQFTPQEFRVLEQLMVHAEHITFSLTADKPSYEREPHELELFRMTGKTYYRLHQKAKELNLDITYKELSGTERHTKTPELAHLEAQYEARPAIPYAEKQEALTVMQAANRRAELEGIAREIHALVREKGYRYKDVAILARQPEDYKDMVKEVFADYEIPYFIDGKASMLNHPLIEFIRSSLDVLKGNWRYEAVFRCVKTELLFPLNEPKAKVREQVDQLENYCIAYGIKGDRWTKGDRFQYRRFVSLDDDFAQTDQEIEMENMLNDTRDWIVPPLFQLQKRMKKAKTVQEKAEALYRYLEETDVPLKLDQERQRAEDDGRIIEAQQHQQAWDAVIQLLEEFVEMMGDDEISLDLFQQMIEAGAESLTFSLIPPALDQVFVGNMDLSRMYGTSCTFVLGANDGVLPARPDENGVLSDDDREWLKTIGVELSSGGRERLLDEHFLIYMAFSSPSDRLYVSYPIADAEGKTLLPSMIVKRLEELFPHHKERLLTNEPEQVSDEEQLMYVVNKSVAQSFTASQLRLWTREYDISDVWWSTYNVLMSEQDRLQSKKLFSSLFFRNEVKQLERSVSRQLYGERIQGSVSRMETFNACPFSHFASHGLHLKERQFFKLEAPDIGQLFHSSLKLISDRLREQKLDWRDLTKEQCELFSYDAVERLAPKLQKEILLSSNRHYYVKEKLQKIVTRVSGILSEHAKASGFVPIGLELGFGGKGPLPPLTFQLKNGCTMELVGRIDRVDKAESSKGLLLRIVDYKSSDKGLDLAEVYYGLALQMLTYLDLSITHSADWLGMRATPAGVLYFHIHDPMIQSNLPLGLDEIEQEIFKKFKMKGLLLGDQEVVRLMDTTLQEGRSNIINAGLKKDGSLRSDSAAVGEKEFDLLTKHVRRTFQEAGEQITDGRVSIEPYKMKNKTPCTYCAFKSVCQFDESLEENEYRPLKAEKDKTILEWIKKEADGNEHS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	1166 (926)
Sequences:	2985 (2498)
Seq/√Len:	82.1

BACSU - ADDB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
609_A	667_V	7.294	1.00
34_P	203_A	7.131	1.00
327_I	607_L	6.795	1.00
368_I	588_V	5.820	1.00
330_E	333_A	4.708	1.00
331_I	345_V	4.328	1.00
344_D	602_S	4.269	1.00
330_E	666_Y	3.980	1.00
893_V	896_V	3.958	1.00
330_E	605_F	3.794	1.00
175_S	178_D	3.783	1.00
810_G	813_L	3.612	1.00
141_R	166_S	3.519	1.00
341_R	586_D	3.505	1.00
171_Q	174_K	3.453	1.00
775_L	779_V	3.447	1.00
340_Y	603_C	3.365	1.00
175_S	179_Q	3.358	1.00
606_V	667_V	3.223	1.00
350_R	650_E	3.169	1.00
605_F	666_Y	3.167	1.00
347_I	363_F	3.152	1.00
986_L	1004_A	3.144	1.00
852_T	855_Q	3.134	1.00
99_L	175_S	3.121	1.00
328_A	366_Y	3.067	1.00
383_L	540_A	3.056	1.00
687_R	691_L	3.048	1.00
602_S	662_S	3.003	1.00
600_G	662_S	3.002	1.00
813_L	817_Q	2.990	1.00
591_G	601_T	2.988	1.00
684_I	687_R	2.953	1.00
487_Q	511_E	2.935	1.00
233_F	236_T	2.886	1.00
970_D	973_E	2.812	1.00
257_K	291_A	2.710	1.00
69_S	186_Y	2.707	1.00
412_L	415_L	2.698	1.00
141_R	170_Q	2.681	1.00
106_E	171_Q	2.668	1.00
329_R	366_Y	2.662	1.00
334_L	666_Y	2.659	1.00
813_L	816_R	2.634	1.00
251_L	255_T	2.606	1.00
507_R	511_E	2.605	1.00
815_E	818_F	2.574	1.00
24_D	28_R	2.556	1.00
25_E	204_H	2.548	1.00
20_N	24_D	2.526	1.00
812_H	815_E	2.525	1.00
688_L	691_L	2.505	1.00
254_M	258_T	2.488	1.00
195_P	219_R	2.485	1.00
892_I	896_V	2.440	1.00
334_L	605_F	2.434	1.00
896_V	899_I	2.434	1.00
46_L	50_E	2.427	1.00
299_A	302_A	2.424	1.00
363_F	370_Y	2.412	1.00
789_Q	940_V	2.411	1.00
335_V	342_Y	2.385	1.00
332_H	336_R	2.356	1.00
602_S	663_D	2.347	1.00
683_M	687_R	2.339	1.00
252_F	255_T	2.327	1.00
993_S	998_G	2.295	1.00
425_Q	477_T	2.285	1.00
87_L	180_Y	2.270	1.00
331_I	605_F	2.243	1.00
776_E	779_V	2.225	1.00
26_L	55_P	2.201	1.00
334_L	603_C	2.184	1.00
325_E	362_V	2.167	1.00
343_K	586_D	2.164	1.00
205_I	224_L	2.162	1.00
686_K	690_E	2.159	1.00
948_K	999_M	2.158	1.00
399_R	402_A	2.144	1.00
387_I	544_V	2.112	1.00
20_N	54_T	2.110	1.00
684_I	691_L	2.082	1.00
333_A	337_E	2.078	1.00
198_E	201_K	2.037	1.00
323_E	668_S	2.024	1.00
834_L	1009_F	2.021	1.00
502_A	565_F	2.015	1.00
779_V	784_Y	2.009	1.00
255_T	259_Y	2.000	1.00
687_R	694_H	2.000	1.00
687_R	690_E	1.999	1.00
824_P	828_Q	1.984	1.00
513_D	516_L	1.980	1.00
778_S	781_R	1.979	1.00
774_Q	779_V	1.965	1.00
987_D	991_T	1.961	1.00
814_K	817_Q	1.958	1.00
830_F	964_S	1.958	1.00
23_Q	54_T	1.952	1.00
355_Y	608_G	1.934	1.00
75_V	190_L	1.929	1.00
771_E	779_V	1.925	1.00
390_S	508_Y	1.923	1.00
1008_Y	1011_I	1.922	1.00
812_H	817_Q	1.913	1.00
778_S	782_Q	1.903	1.00
325_E	366_Y	1.896	1.00
606_V	609_A	1.889	1.00
16_K	20_N	1.888	1.00
328_A	362_V	1.887	1.00
181_L	186_Y	1.875	1.00
416_N	425_Q	1.874	1.00
946_V	989_S	1.868	1.00
651_H	687_R	1.866	1.00
774_Q	778_S	1.866	1.00
334_L	345_V	1.864	1.00
176_L	185_D	1.855	1.00
777_R	780_S	1.838	1.00
813_L	818_F	1.838	1.00
350_R	653_L	1.836	1.00
859_F	862_D	1.823	1.00
370_Y	590_V	1.822	1.00
947_D	960_V	1.818	1.00
92_V	172_M	1.818	1.00
102_E	175_S	1.805	1.00
275_Y	279_S	1.801	1.00
103_H	171_Q	1.800	1.00
324_L	359_V	1.798	1.00
29_A	32_G	1.791	1.00
270_N	273_I	1.790	1.00
332_H	366_Y	1.790	1.00
678_T	681_P	1.780	1.00
41_D	69_S	1.770	1.00
885_V	888_K	1.766	1.00
603_C	666_Y	1.758	1.00
684_I	694_H	1.756	1.00
519_D	538_Q	1.752	1.00
233_F	238_D	1.742	1.00
814_K	818_F	1.732	1.00
209_G	597_R	1.727	1.00
479_D	483_P	1.714	1.00
335_V	345_V	1.698	1.00
945_R	960_V	1.691	1.00
775_L	778_S	1.687	1.00
389_S	405_R	1.676	1.00
780_S	783_L	1.660	1.00
390_S	406_C	1.659	1.00
327_I	668_S	1.655	1.00
195_P	223_Q	1.655	1.00
85_P	91_G	1.642	1.00
949_A	1002_T	1.633	1.00
332_H	342_Y	1.633	1.00
689_E	693_P	1.630	1.00
88_T	550_E	1.617	1.00
278_L	281_T	1.610	1.00
19_I	51_L	1.610	1.00
775_L	781_R	1.607	1.00
684_I	690_E	1.601	1.00
297_Y	300_R	1.595	1.00
688_L	692_F	1.591	1.00
499_Q	503_E	1.588	1.00
812_H	818_F	1.587	1.00
248_E	252_F	1.586	1.00
252_F	256_G	1.582	1.00
886_K	893_V	1.579	1.00
905_K	949_A	1.576	1.00
284_H	658_F	1.570	1.00
548_L	565_F	1.568	1.00
277_E	280_G	1.566	1.00
102_E	171_Q	1.556	1.00
304_P	307_E	1.554	1.00
743_W	746_T	1.553	1.00
787_R	790_G	1.552	1.00
252_F	258_T	1.550	1.00
603_C	664_R	1.545	1.00
780_S	784_Y	1.542	1.00
688_L	694_H	1.534	0.99
878_S	882_H	1.531	0.99
136_E	139_D	1.531	0.99
728_S	731_R	1.522	0.99
777_R	781_R	1.518	0.99
686_K	691_L	1.513	0.99
167_I	170_Q	1.512	0.99
691_L	694_H	1.512	0.99
719_K	731_R	1.501	0.99
917_G	942_R	1.500	0.99
723_Q	731_R	1.500	0.99
327_I	605_F	1.499	0.99
363_F	590_V	1.491	0.99
313_T	664_R	1.479	0.99
685_V	688_L	1.478	0.99
807_A	815_E	1.475	0.99
687_R	695_H	1.474	0.99
95_L	175_S	1.469	0.99
905_K	909_F	1.466	0.99
326_G	668_S	1.463	0.99
862_D	866_R	1.461	0.99
330_E	334_L	1.454	0.99
362_V	366_Y	1.454	0.99
779_V	783_L	1.449	0.99
575_S	578_F	1.448	0.99
779_V	782_Q	1.444	0.99
809_H	815_E	1.444	0.99
656_M	659_S	1.443	0.99
171_Q	175_S	1.442	0.99
913_G	916_L	1.440	0.99
209_G	217_E	1.439	0.99
716_V	722_A	1.436	0.99
121_A	125_R	1.436	0.99
746_T	749_V	1.434	0.99
832_S	836_L	1.429	0.99
359_V	590_V	1.427	0.99
38_L	221_L	1.422	0.99
324_L	607_L	1.419	0.99
771_E	778_S	1.419	0.99
1006_V	1010_H	1.416	0.99
684_I	688_L	1.415	0.99
572_G	576_L	1.415	0.99
407_V	415_L	1.414	0.99
210_F	213_F	1.409	0.99
174_K	178_D	1.407	0.99
300_R	303_I	1.396	0.99
720_S	730_L	1.391	0.99
74_R	78_H	1.387	0.99
64_Q	74_R	1.387	0.99
974_V	1008_Y	1.386	0.99
806_F	812_H	1.385	0.99
471_E	475_N	1.379	0.99
69_S	182_H	1.366	0.99
69_S	76_L	1.363	0.99
475_N	478_R	1.362	0.99
614_L	650_E	1.362	0.99
371_F	587_Q	1.361	0.99
373_D	595_L	1.358	0.99
573_A	576_L	1.355	0.99
758_Q	762_L	1.354	0.99
559_E	563_D	1.347	0.99
79_T	82_M	1.346	0.99
393_V	406_C	1.344	0.99
694_H	697_E	1.344	0.99
327_I	359_V	1.342	0.99
331_I	342_Y	1.341	0.99
727_A	731_R	1.340	0.99
806_F	813_L	1.337	0.99
349_A	356_K	1.336	0.99
775_L	784_Y	1.334	0.99
807_A	813_L	1.328	0.99
693_P	697_E	1.327	0.99
725_F	728_S	1.325	0.99
362_V	365_D	1.323	0.98
294_E	299_A	1.323	0.98
139_D	142_R	1.322	0.98
810_G	815_E	1.320	0.98
335_V	340_Y	1.315	0.98
593_M	614_L	1.314	0.98
349_A	590_V	1.314	0.98
948_K	957_L	1.308	0.98
137_P	166_S	1.306	0.98
234_S	238_D	1.305	0.98
630_E	634_T	1.305	0.98
267_K	272_D	1.300	0.98
949_A	958_R	1.298	0.98
69_S	214_T	1.297	0.98
544_V	548_L	1.296	0.98
687_R	697_E	1.295	0.98
688_L	703_E	1.294	0.98
811_L	814_K	1.292	0.98
810_G	818_F	1.288	0.98
722_A	725_F	1.284	0.98
407_V	481_I	1.284	0.98
1005_G	1008_Y	1.282	0.98
392_D	570_E	1.281	0.98
688_L	705_E	1.279	0.98
724_S	727_A	1.277	0.98
173_E	189_L	1.276	0.98
471_E	474_L	1.276	0.98
721_V	725_F	1.272	0.98
778_S	784_Y	1.272	0.98
806_F	809_H	1.267	0.98
561_S	564_L	1.266	0.98
145_E	149_A	1.266	0.98
210_F	218_F	1.266	0.98
137_P	170_Q	1.266	0.98
239_K	656_M	1.264	0.98
236_T	239_K	1.257	0.98
688_L	695_H	1.257	0.98
235_L	252_F	1.255	0.98
69_S	181_L	1.254	0.98
774_Q	777_R	1.254	0.98
230_H	236_T	1.253	0.98
779_V	786_E	1.253	0.98
719_K	730_L	1.250	0.98
24_D	27_R	1.247	0.98
832_S	835_K	1.247	0.98
746_T	750_L	1.246	0.98
835_K	839_D	1.246	0.98
593_M	609_A	1.241	0.98
702_N	705_E	1.234	0.98
607_L	668_S	1.227	0.98
811_L	815_E	1.227	0.98
739_I	742_V	1.226	0.98
727_A	730_L	1.226	0.98
559_E	562_L	1.225	0.97
887_E	890_Q	1.225	0.97
686_K	695_H	1.224	0.97
742_V	746_T	1.224	0.97
947_D	958_R	1.223	0.97
792_V	796_E	1.223	0.97
775_L	780_S	1.222	0.97
626_D	630_E	1.222	0.97
959_I	989_S	1.219	0.97
325_E	365_D	1.217	0.97
809_H	812_H	1.213	0.97
720_S	723_Q	1.208	0.97
774_Q	781_R	1.207	0.97
170_Q	174_K	1.206	0.97
858_L	862_D	1.206	0.97
629_R	632_L	1.199	0.97
412_L	484_P	1.198	0.97
255_T	258_T	1.190	0.97
99_L	103_H	1.184	0.97
385_E	389_S	1.184	0.97
236_T	241_S	1.183	0.97
683_M	686_K	1.181	0.97
342_Y	369_P	1.180	0.97
356_K	590_V	1.179	0.97
807_A	810_G	1.179	0.97
569_I	572_G	1.178	0.97
739_I	743_W	1.176	0.97
720_S	727_A	1.176	0.97
277_E	281_T	1.174	0.97
39_V	597_R	1.170	0.97
287_T	290_L	1.169	0.97
805_H	818_F	1.167	0.97
972_A	976_Y	1.165	0.97
658_F	665_L	1.163	0.97
774_Q	780_S	1.157	0.96
252_F	259_Y	1.151	0.96
949_A	952_S	1.150	0.96
291_A	297_Y	1.149	0.96
853_K	857_E	1.149	0.96
893_V	899_I	1.148	0.96
217_E	597_R	1.147	0.96
723_Q	726_T	1.146	0.96
631_W	634_T	1.146	0.96
500_E	503_E	1.146	0.96
689_E	694_H	1.145	0.96
744_W	747_Y	1.145	0.96
886_K	890_Q	1.132	0.96
906_A	909_F	1.129	0.96
604_T	660_S	1.127	0.96
294_E	297_Y	1.126	0.96
809_H	818_F	1.125	0.96
776_E	781_R	1.123	0.96
278_L	282_E	1.119	0.96
806_F	814_K	1.118	0.96
249_L	252_F	1.115	0.96
235_L	238_D	1.114	0.96
329_R	333_A	1.112	0.96
693_P	696_K	1.110	0.96
860_S	886_K	1.108	0.95
345_V	605_F	1.101	0.95
562_L	565_F	1.101	0.95
687_R	705_E	1.096	0.95
715_Y	719_K	1.096	0.95
781_R	784_Y	1.094	0.95
251_L	259_Y	1.094	0.95
886_K	896_V	1.090	0.95
107_F	110_Y	1.088	0.95
718_N	722_A	1.088	0.95
441_D	444_T	1.088	0.95
509_L	541_W	1.086	0.95
791_S	796_E	1.086	0.95
333_A	338_K	1.085	0.95
191_A	219_R	1.085	0.95
1003_P	1006_V	1.083	0.95
816_R	819_F	1.077	0.95
952_S	958_R	1.075	0.95
488_L	511_E	1.071	0.95
130_F	133_Y	1.068	0.94
976_Y	979_A	1.066	0.94
723_Q	727_A	1.064	0.94
86_F	186_Y	1.063	0.94
84_R	181_L	1.063	0.94
551_F	564_L	1.061	0.94
813_L	819_F	1.060	0.94
519_D	523_Q	1.058	0.94
856_C	886_K	1.057	0.94
810_G	814_K	1.057	0.94
697_E	703_E	1.056	0.94
239_K	594_D	1.056	0.94
341_R	344_D	1.055	0.94
495_A	499_Q	1.053	0.94
793_S	796_E	1.052	0.94
248_E	255_T	1.052	0.94
683_M	688_L	1.050	0.94
949_A	1003_P	1.048	0.94
886_K	892_I	1.047	0.94
958_R	1005_G	1.047	0.94
806_F	815_E	1.047	0.94
488_L	508_Y	1.044	0.94
49_Y	53_K	1.042	0.94
8_G	209_G	1.040	0.94
95_L	99_L	1.040	0.94
578_F	583_P	1.040	0.94
138_E	142_R	1.036	0.94
918_F	941_G	1.035	0.93
805_H	815_E	1.035	0.93
606_V	657_A	1.035	0.93
204_H	230_H	1.031	0.93
8_G	597_R	1.031	0.93
777_R	784_Y	1.030	0.93
142_R	145_E	1.030	0.93
690_E	693_P	1.027	0.93
716_V	721_V	1.027	0.93
725_F	731_R	1.025	0.93
805_H	812_H	1.023	0.93
564_L	568_M	1.022	0.93
502_A	548_L	1.022	0.93
69_S	187_L	1.020	0.93
694_H	698_R	1.020	0.93
743_W	747_Y	1.020	0.93
701_T	705_E	1.019	0.93
654_I	658_F	1.019	0.93
1007_L	1010_H	1.016	0.93
721_V	730_L	1.014	0.93
815_E	819_F	1.014	0.93
892_I	899_I	1.013	0.93
126_M	165_L	1.013	0.93
990_I	1000_R	1.011	0.93
714_M	717_V	1.011	0.93
76_L	193_H	1.010	0.93
96_L	168_L	1.010	0.93
471_E	478_R	1.009	0.93
691_L	697_E	1.008	0.93
173_E	177_A	1.004	0.92
748_N	751_M	1.004	0.92
277_E	282_E	1.000	0.92
809_H	814_K	1.000	0.92
757_L	760_K	0.994	0.92
233_F	237_A	0.993	0.92
18_I	206_Y	0.992	0.92
773_K	779_V	0.991	0.92
683_M	694_H	0.987	0.92
480_W	484_P	0.986	0.92
292_H	296_Q	0.986	0.92
722_A	727_A	0.985	0.92
104_K	123_V	0.982	0.92
239_K	348_L	0.982	0.92
597_R	655_Y	0.982	0.92
181_L	189_L	0.981	0.92
687_R	693_P	0.980	0.91
691_L	695_H	0.980	0.91
75_V	224_L	0.979	0.91
277_E	312_L	0.978	0.91
558_D	564_L	0.978	0.91
481_I	485_L	0.978	0.91
323_E	608_G	0.977	0.91
747_Y	751_M	0.976	0.91
726_T	731_R	0.976	0.91
810_G	817_Q	0.974	0.91
18_I	234_S	0.974	0.91
919_G	938_E	0.973	0.91
604_T	661_P	0.970	0.91
235_L	241_S	0.969	0.91
347_I	389_S	0.969	0.91
300_R	304_P	0.966	0.91
211_Y	239_K	0.965	0.91
890_Q	894_T	0.965	0.91
239_K	659_S	0.963	0.91
857_E	861_Y	0.962	0.91
655_Y	659_S	0.962	0.91
324_L	328_A	0.960	0.91
683_M	696_K	0.960	0.91
918_F	988_L	0.956	0.90
330_E	664_R	0.956	0.90
806_F	817_Q	0.956	0.90
8_G	234_S	0.955	0.90
217_E	594_D	0.955	0.90
273_I	277_E	0.954	0.90
726_T	730_L	0.952	0.90
741_D	745_S	0.951	0.90
160_E	163_H	0.950	0.90
313_T	316_Q	0.950	0.90
242_Y	597_R	0.949	0.90
89_S	92_V	0.949	0.90
597_R	656_M	0.948	0.90
198_E	202_G	0.947	0.90
240_P	247_H	0.945	0.90
248_E	251_L	0.944	0.90
11_G	14_K	0.944	0.90
392_D	402_A	0.943	0.90
360_K	364_A	0.941	0.90
773_K	778_S	0.941	0.90
212_Q	597_R	0.941	0.90
96_L	128_T	0.941	0.90
473_M	477_T	0.939	0.90
801_C	804_S	0.938	0.90
190_L	220_V	0.934	0.89
943_I	946_V	0.931	0.89
22_I	51_L	0.930	0.89
8_G	242_Y	0.928	0.89
768_F	771_E	0.927	0.89
692_F	695_H	0.926	0.89
714_M	726_T	0.925	0.89
219_R	222_E	0.924	0.89
310_E	313_T	0.924	0.89
697_E	701_T	0.923	0.89
886_K	899_I	0.921	0.89
237_A	252_F	0.921	0.89
812_H	819_F	0.921	0.89
689_E	695_H	0.917	0.89
144_A	166_S	0.916	0.88
806_F	810_G	0.916	0.88
693_P	703_E	0.914	0.88
484_P	488_L	0.911	0.88
348_L	604_T	0.911	0.88
334_L	340_Y	0.909	0.88
211_Y	656_M	0.908	0.88
48_E	52_A	0.907	0.88
501_K	505_L	0.906	0.88
684_I	693_P	0.906	0.88
234_S	242_Y	0.905	0.88
340_Y	345_V	0.905	0.88
230_H	233_F	0.905	0.88
656_M	660_S	0.904	0.88
300_R	305_Y	0.904	0.88
715_Y	718_N	0.903	0.88
616_A	643_G	0.900	0.88
617_R	620_E	0.900	0.88
169_Y	173_E	0.899	0.88
335_V	341_R	0.899	0.88
441_D	445_K	0.898	0.87
237_A	240_P	0.896	0.87
212_Q	656_M	0.892	0.87
8_G	46_L	0.892	0.87
552_V	556_G	0.892	0.87
351_Q	357_D	0.891	0.87
667_V	688_L	0.891	0.87
91_G	94_M	0.889	0.87
292_H	297_Y	0.888	0.87
986_L	990_I	0.887	0.87
716_V	730_L	0.887	0.87
515_P	519_D	0.885	0.87
235_L	239_K	0.885	0.87
594_D	597_R	0.885	0.87
723_Q	730_L	0.885	0.87
918_F	943_I	0.882	0.87
236_T	240_P	0.882	0.87
172_M	182_H	0.880	0.86
373_D	795_M	0.879	0.86
68_F	213_F	0.879	0.86
605_F	668_S	0.876	0.86
272_D	600_G	0.876	0.86
1006_V	1011_I	0.875	0.86
731_R	734_T	0.874	0.86
103_H	106_E	0.872	0.86
310_E	314_V	0.870	0.86
721_V	731_R	0.869	0.86
192_E	196_L	0.869	0.86
789_Q	792_V	0.868	0.86
598_M	660_S	0.867	0.86
701_T	704_P	0.864	0.85
745_S	749_V	0.864	0.85
916_L	946_V	0.864	0.85
973_E	976_Y	0.863	0.85
130_F	169_Y	0.863	0.85
235_L	242_Y	0.861	0.85
484_P	487_Q	0.861	0.85
212_Q	598_M	0.859	0.85
6_L	277_E	0.858	0.85
290_L	294_E	0.858	0.85
69_S	184_E	0.858	0.85
217_E	655_Y	0.858	0.85
10_S	40_P	0.857	0.85
731_R	735_R	0.857	0.85
730_L	734_T	0.856	0.85
209_G	655_Y	0.855	0.85
209_G	242_Y	0.855	0.85
346_A	601_T	0.855	0.85
777_R	783_L	0.855	0.85
424_E	428_Q	0.855	0.85
766_L	770_N	0.854	0.85
416_N	424_E	0.854	0.85
239_K	242_Y	0.852	0.85
839_D	945_R	0.851	0.85
396_G	399_R	0.850	0.84
676_G	681_P	0.848	0.84
593_M	657_A	0.844	0.84
695_H	698_R	0.844	0.84
205_I	405_R	0.843	0.84
349_A	607_L	0.843	0.84
135_L	138_E	0.842	0.84
279_S	283_R	0.841	0.84
87_L	92_V	0.841	0.84
280_G	312_L	0.840	0.84
290_L	293_L	0.839	0.84
689_E	697_E	0.838	0.84
506_Y	545_I	0.837	0.84
394_L	488_L	0.836	0.83
690_E	695_H	0.835	0.83
294_E	301_P	0.834	0.83
129_E	629_R	0.834	0.83
209_G	213_F	0.832	0.83
17_L	20_N	0.831	0.83
744_W	748_N	0.831	0.83
537_H	540_A	0.831	0.83
235_L	240_P	0.829	0.83
52_A	60_M	0.828	0.83
123_V	165_L	0.828	0.83
317_A	668_S	0.828	0.83
568_M	576_L	0.827	0.83
38_L	207_V	0.827	0.83
212_Q	659_S	0.827	0.83
144_A	159_S	0.827	0.83
574_E	578_F	0.827	0.83
18_I	47_M	0.824	0.83
225_M	231_I	0.824	0.83
203_A	226_V	0.823	0.82
311_A	315_M	0.821	0.82
353_E	356_K	0.820	0.82
686_K	694_H	0.820	0.82
8_G	212_Q	0.820	0.82
625_S	630_E	0.819	0.82
563_D	567_Q	0.819	0.82
125_R	621_N	0.819	0.82
297_Y	302_A	0.818	0.82
683_M	691_L	0.818	0.82
596_S	601_T	0.817	0.82
301_P	305_Y	0.817	0.82
714_M	725_F	0.817	0.82
693_P	705_E	0.816	0.82
76_L	186_Y	0.816	0.82
747_Y	750_L	0.816	0.82
351_Q	354_D	0.816	0.82
19_I	23_Q	0.815	0.82
295_A	298_E	0.814	0.82
56_D	959_I	0.814	0.82
131_K	169_Y	0.814	0.82
719_K	724_S	0.814	0.82
630_E	635_I	0.813	0.82
946_V	957_L	0.813	0.82
789_Q	793_S	0.813	0.82
812_H	816_R	0.812	0.82
572_G	575_S	0.812	0.82
861_Y	890_Q	0.812	0.82
174_K	177_A	0.812	0.82
790_G	795_M	0.811	0.82
281_T	285_T	0.811	0.82
143_M	147_G	0.811	0.82
561_S	569_I	0.808	0.81
724_S	730_L	0.807	0.81
714_M	728_S	0.806	0.81
429_L	440_G	0.805	0.81
207_V	231_I	0.805	0.81
697_E	700_L	0.804	0.81
273_I	281_T	0.803	0.81
383_L	537_H	0.803	0.81
283_R	287_T	0.802	0.81
657_A	660_S	0.802	0.81
313_T	330_E	0.801	0.81
324_L	362_V	0.800	0.81
503_E	507_R	0.800	0.81
725_F	729_Q	0.799	0.81
222_E	258_T	0.799	0.81
360_K	372_I	0.799	0.81
687_R	703_E	0.799	0.81
773_K	780_S	0.799	0.81
715_Y	726_T	0.799	0.81
807_A	818_F	0.797	0.80
144_A	163_H	0.797	0.80
714_M	731_R	0.797	0.80
167_I	171_Q	0.796	0.80
857_E	894_T	0.796	0.80
778_S	783_L	0.796	0.80
242_Y	594_D	0.795	0.80
120_T	124_E	0.793	0.80
312_L	315_M	0.793	0.80
811_L	816_R	0.792	0.80
76_L	190_L	0.790	0.80
209_G	598_M	0.788	0.80
776_E	780_S	0.787	0.80
826_I	964_S	0.787	0.80
697_E	702_N	0.786	0.80
312_L	316_Q	0.786	0.80
743_W	749_V	0.786	0.80
8_G	599_Y	0.784	0.79
686_K	689_E	0.782	0.79
805_H	810_G	0.782	0.79
241_S	656_M	0.781	0.79
568_M	572_G	0.780	0.79
628_D	632_L	0.780	0.79
598_M	656_M	0.778	0.79
209_G	212_Q	0.778	0.79
658_F	667_V	0.776	0.79
346_A	589_F	0.776	0.79
211_Y	652_F	0.776	0.79
391_L	505_L	0.776	0.79
697_E	704_P	0.776	0.79
830_F	1011_I	0.775	0.79
718_N	721_V	0.775	0.79
687_R	696_K	0.774	0.78
25_E	35_I	0.774	0.78
695_H	702_N	0.774	0.78
805_H	814_K	0.773	0.78
209_G	599_Y	0.772	0.78
502_A	552_V	0.770	0.78
43_M	598_M	0.770	0.78
726_T	729_Q	0.769	0.78
437_G	440_G	0.768	0.78
390_S	488_L	0.768	0.78
334_L	664_R	0.768	0.78
724_S	728_S	0.768	0.78
983_L	1004_A	0.766	0.78
8_G	213_F	0.766	0.78
332_H	368_I	0.766	0.78
27_R	58_G	0.765	0.78
236_T	600_G	0.765	0.78
317_A	326_G	0.765	0.78
695_H	701_T	0.764	0.78
135_L	140_I	0.764	0.78
298_E	302_A	0.764	0.78
8_G	15_T	0.764	0.78
559_E	568_M	0.763	0.77
253_R	296_Q	0.762	0.77
242_Y	656_M	0.761	0.77
719_K	722_A	0.758	0.77
92_V	176_L	0.758	0.77
472_N	476_D	0.758	0.77
25_E	206_Y	0.757	0.77
211_Y	598_M	0.755	0.77
842_R	851_L	0.755	0.77
39_V	209_G	0.754	0.77
163_H	167_I	0.753	0.77
274_T	277_E	0.753	0.77
209_G	241_S	0.753	0.77
911_P	948_K	0.752	0.76
205_I	384_I	0.752	0.76
829_L	884_Y	0.751	0.76
762_L	766_L	0.751	0.76
394_L	505_L	0.751	0.76
199_D	202_G	0.751	0.76
581_I	587_Q	0.751	0.76
73_W	172_M	0.750	0.76
683_M	695_H	0.749	0.76
651_H	684_I	0.749	0.76
947_D	1003_P	0.749	0.76
398_W	403_V	0.748	0.76
298_E	304_P	0.746	0.76
542_D	546_Q	0.745	0.76
646_R	650_E	0.745	0.76
470_M	474_L	0.745	0.76
211_Y	649_D	0.744	0.76
79_T	415_L	0.744	0.76
131_K	185_D	0.742	0.75
721_V	727_A	0.742	0.75
243_E	645_E	0.741	0.75
442_R	445_K	0.740	0.75
395_K	563_D	0.739	0.75
579_S	587_Q	0.739	0.75
36_I	658_F	0.739	0.75
687_R	702_N	0.739	0.75
821_L	883_Y	0.738	0.75
720_S	726_T	0.738	0.75
957_L	999_M	0.738	0.75
854_E	858_L	0.737	0.75
17_L	21_S	0.737	0.75
90_T	569_I	0.737	0.75
794_R	797_T	0.736	0.75
690_E	697_E	0.736	0.75
340_Y	663_D	0.735	0.75
829_L	889_L	0.735	0.75
855_Q	858_L	0.733	0.75
797_T	800_A	0.732	0.74
770_N	779_V	0.731	0.74
626_D	645_E	0.731	0.74
747_Y	753_E	0.731	0.74
688_L	693_P	0.730	0.74
88_T	342_Y	0.729	0.74
234_S	241_S	0.728	0.74
507_R	510_E	0.728	0.74
186_Y	221_L	0.728	0.74
538_Q	542_D	0.728	0.74
43_M	599_Y	0.727	0.74
594_D	598_M	0.727	0.74
569_I	573_A	0.727	0.74
632_L	635_I	0.726	0.74
649_D	988_L	0.726	0.74
722_A	726_T	0.726	0.74
45_F	48_E	0.725	0.74
346_A	587_Q	0.724	0.74
119_F	124_E	0.724	0.74
301_P	307_E	0.724	0.74
72_A	220_V	0.723	0.74
296_Q	300_R	0.722	0.73
236_T	242_Y	0.721	0.73
42_Q	597_R	0.720	0.73
138_E	141_R	0.719	0.73
742_V	745_S	0.719	0.73
610_N	670_P	0.719	0.73
647_L	650_E	0.717	0.73
730_L	733_W	0.717	0.73
562_L	567_Q	0.717	0.73
209_G	594_D	0.717	0.73
686_K	697_E	0.717	0.73
719_K	725_F	0.717	0.73
231_I	235_L	0.716	0.73
310_E	315_M	0.716	0.73
16_K	54_T	0.716	0.73
690_E	703_E	0.716	0.73
99_L	168_L	0.716	0.73
565_F	569_I	0.715	0.73
233_F	255_T	0.714	0.73
999_M	1003_P	0.713	0.73
186_Y	244_R	0.712	0.72
648_L	651_H	0.712	0.72
1009_F	1014_P	0.712	0.72
75_V	79_T	0.711	0.72
948_K	951_S	0.711	0.72
5_F	255_T	0.710	0.72
212_Q	599_Y	0.710	0.72
601_T	604_T	0.710	0.72
972_A	975_Y	0.710	0.72
212_Q	660_S	0.709	0.72
758_Q	764_S	0.708	0.72
585_L	959_I	0.708	0.72
86_F	181_L	0.707	0.72
425_Q	473_M	0.707	0.72
809_H	813_L	0.706	0.72
505_L	575_S	0.705	0.72
766_L	769_R	0.705	0.72
275_Y	278_L	0.704	0.72
71_L	79_T	0.704	0.72
254_M	257_K	0.704	0.72
563_D	569_I	0.704	0.72
296_Q	299_A	0.703	0.71
760_K	765_S	0.703	0.71
161_K	164_D	0.703	0.71
603_C	663_D	0.701	0.71
716_V	719_K	0.701	0.71
211_Y	235_L	0.701	0.71
561_S	565_F	0.701	0.71
515_P	542_D	0.701	0.71
615_P	650_E	0.700	0.71
13_G	208_D	0.699	0.71
274_T	281_T	0.699	0.71
982_M	988_L	0.698	0.71
391_L	395_K	0.698	0.71
316_Q	669_Y	0.697	0.71
249_L	255_T	0.696	0.71
548_L	551_F	0.696	0.71
695_H	703_E	0.696	0.71
234_S	597_R	0.695	0.71
890_Q	893_V	0.695	0.71
213_F	217_E	0.693	0.70
694_H	701_T	0.693	0.70
35_I	206_Y	0.693	0.70
579_S	582_P	0.693	0.70
8_G	39_V	0.692	0.70
378_M	540_A	0.691	0.70
722_A	732_L	0.691	0.70
240_P	244_R	0.691	0.70
251_L	256_G	0.689	0.70
209_G	656_M	0.688	0.70
232_T	235_L	0.687	0.70
905_K	947_D	0.687	0.70
583_P	589_F	0.687	0.70
720_S	731_R	0.687	0.70
717_V	720_S	0.687	0.70
609_A	668_S	0.686	0.70
66_F	69_S	0.686	0.70
630_E	638_E	0.686	0.70
759_S	762_L	0.685	0.70
628_D	631_W	0.684	0.69
74_R	77_Q	0.683	0.69
294_E	298_E	0.682	0.69
386_F	512_T	0.682	0.69
10_S	656_M	0.681	0.69
207_V	496_K	0.681	0.69
440_G	443_W	0.681	0.69
793_S	975_Y	0.680	0.69
298_E	301_P	0.680	0.69
546_Q	550_E	0.680	0.69
8_G	43_M	0.680	0.69
793_S	889_L	0.680	0.69
322_A	731_R	0.680	0.69
14_K	655_Y	0.679	0.69
75_V	193_H	0.679	0.69
264_Q	268_E	0.679	0.69
897_S	960_V	0.678	0.69
342_Y	368_I	0.678	0.69
331_I	588_V	0.678	0.69
742_V	749_V	0.677	0.69
770_N	775_L	0.677	0.69
750_L	753_E	0.677	0.69
144_A	162_L	0.677	0.69
774_Q	784_Y	0.676	0.69
39_V	242_Y	0.676	0.69
393_V	403_V	0.676	0.69
920_G	929_F	0.675	0.68
534_A	537_H	0.675	0.68
947_D	951_S	0.673	0.68
310_E	316_Q	0.673	0.68
390_S	394_L	0.671	0.68
474_L	477_T	0.670	0.68
478_R	481_I	0.670	0.68
103_H	167_I	0.670	0.68
334_L	338_K	0.670	0.68
291_A	294_E	0.669	0.68
694_H	703_E	0.669	0.68
55_P	71_L	0.669	0.68
7_V	237_A	0.668	0.68
598_M	652_F	0.667	0.67
719_K	726_T	0.667	0.67
8_G	241_S	0.667	0.67
212_Q	596_S	0.666	0.67
378_M	578_F	0.662	0.67
135_L	139_D	0.662	0.67
425_Q	480_W	0.661	0.67
631_W	635_I	0.660	0.67
31_F	41_D	0.660	0.67
716_V	720_S	0.660	0.67
324_L	358_M	0.659	0.67
213_F	597_R	0.658	0.66
191_A	194_I	0.658	0.66
288_P	293_L	0.657	0.66
758_Q	761_K	0.657	0.66
404_F	426_V	0.656	0.66
806_F	818_F	0.656	0.66
717_V	730_L	0.656	0.66
563_D	568_M	0.656	0.66
892_I	898_G	0.655	0.66
349_A	359_V	0.655	0.66
685_V	690_E	0.655	0.66
241_S	597_R	0.654	0.66
23_Q	27_R	0.654	0.66
129_E	625_S	0.653	0.66
830_F	834_L	0.653	0.66
234_S	656_M	0.653	0.66
892_I	895_R	0.653	0.66
591_G	596_S	0.653	0.66
211_Y	592_N	0.653	0.66
41_D	73_W	0.652	0.66
375_K	501_K	0.652	0.66
594_D	649_D	0.651	0.66
687_R	701_T	0.651	0.66
54_T	57_M	0.650	0.66
319_N	322_A	0.650	0.66
39_V	214_T	0.649	0.65
194_I	223_Q	0.648	0.65
557_D	561_S	0.648	0.65
288_P	292_H	0.647	0.65
348_L	655_Y	0.647	0.65
688_L	793_S	0.647	0.65
10_S	599_Y	0.646	0.65
465_D	468_I	0.646	0.65
919_G	940_V	0.646	0.65
626_D	641_S	0.645	0.65
979_A	983_L	0.645	0.65
485_L	488_L	0.644	0.65
714_M	721_V	0.643	0.65
952_S	1002_T	0.643	0.65
411_L	414_P	0.642	0.65
804_S	808_S	0.641	0.64
858_L	861_Y	0.641	0.64
69_S	594_D	0.641	0.64
859_F	863_A	0.641	0.64
803_F	806_F	0.640	0.64
234_S	237_A	0.639	0.64
236_T	272_D	0.639	0.64
351_Q	355_Y	0.639	0.64
693_P	702_N	0.639	0.64
273_I	278_L	0.638	0.64
297_Y	301_P	0.638	0.64
971_L	974_V	0.638	0.64
28_R	32_G	0.637	0.64
771_E	781_R	0.637	0.64
743_W	750_L	0.637	0.64
272_D	604_T	0.636	0.64
72_A	186_Y	0.636	0.64
549_E	552_V	0.635	0.64
251_L	258_T	0.635	0.64
48_E	220_V	0.634	0.64
505_L	548_L	0.633	0.63
69_S	239_K	0.633	0.63
97_R	120_T	0.633	0.63
571_A	576_L	0.631	0.63
39_V	47_M	0.631	0.63
618_P	646_R	0.631	0.63
691_L	703_E	0.631	0.63
700_L	703_E	0.630	0.63
805_H	811_L	0.629	0.63
386_F	409_T	0.629	0.63
790_G	794_R	0.629	0.63
287_T	694_H	0.629	0.63
326_G	330_E	0.629	0.63
698_R	702_N	0.628	0.63
624_L	918_F	0.628	0.63
145_E	905_K	0.626	0.63
212_Q	649_D	0.626	0.63
177_A	189_L	0.625	0.62
185_D	214_T	0.625	0.62
697_E	705_E	0.625	0.62
765_S	770_N	0.625	0.62
236_T	649_D	0.624	0.62
746_T	766_L	0.623	0.62
558_D	563_D	0.623	0.62
739_I	746_T	0.623	0.62
600_G	660_S	0.622	0.62
236_T	655_Y	0.622	0.62
688_L	702_N	0.622	0.62
276_K	279_S	0.621	0.62
478_R	482_V	0.621	0.62
301_P	306_A	0.621	0.62
391_L	394_L	0.621	0.62
209_G	272_D	0.621	0.62
387_I	505_L	0.621	0.62
722_A	730_L	0.619	0.62
210_F	251_L	0.619	0.62
151_E	154_G	0.619	0.62
560_I	563_D	0.619	0.62
21_S	232_T	0.618	0.62
253_R	256_G	0.618	0.62
560_I	568_M	0.618	0.62
564_L	571_A	0.618	0.62
98_K	175_S	0.617	0.61
781_R	785_G	0.617	0.61
332_H	335_V	0.617	0.61
11_G	272_D	0.617	0.61
675_E	681_P	0.616	0.61
66_F	70_R	0.616	0.61
233_F	239_K	0.616	0.61
230_H	234_S	0.616	0.61
677_K	681_P	0.615	0.61
50_E	209_G	0.615	0.61
107_F	119_F	0.615	0.61
7_V	252_F	0.613	0.61
240_P	252_F	0.613	0.61
243_E	626_D	0.613	0.61
561_S	572_G	0.612	0.61
771_E	780_S	0.612	0.61
371_F	581_I	0.611	0.61
384_I	504_A	0.611	0.61
425_Q	428_Q	0.611	0.61
211_Y	660_S	0.611	0.61
123_V	971_L	0.610	0.61
683_M	705_E	0.610	0.61
684_I	703_E	0.609	0.60
773_K	783_L	0.609	0.60
481_I	484_P	0.609	0.60
971_L	1013_D	0.608	0.60
392_D	567_Q	0.607	0.60
338_K	664_R	0.607	0.60
195_P	264_Q	0.606	0.60
594_D	656_M	0.606	0.60
358_M	362_V	0.605	0.60
335_V	368_I	0.603	0.60
946_V	1008_Y	0.603	0.60
149_A	159_S	0.603	0.60
610_N	669_Y	0.603	0.60
719_K	723_Q	0.603	0.60
234_S	239_K	0.603	0.60
70_R	574_E	0.602	0.60
688_L	697_E	0.601	0.59
428_Q	474_L	0.601	0.59
742_V	750_L	0.601	0.59
594_D	652_F	0.599	0.59
217_E	242_Y	0.599	0.59
304_P	308_K	0.599	0.59
981_Q	985_Y	0.599	0.59
439_K	442_R	0.599	0.59
839_D	914_L	0.599	0.59
212_Q	592_N	0.599	0.59
292_H	295_A	0.598	0.59
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194_I	220_V	0.597	0.59
26_L	30_P	0.597	0.59
740_S	743_W	0.597	0.59
626_D	629_R	0.597	0.59
53_K	57_M	0.597	0.59
239_K	655_Y	0.596	0.59
132_R	682_S	0.595	0.59
172_M	650_E	0.595	0.59
582_P	585_L	0.595	0.59
725_F	730_L	0.595	0.59
318_A	322_A	0.595	0.59
38_L	68_F	0.595	0.59
696_K	852_T	0.594	0.59
88_T	91_G	0.594	0.59
6_L	17_L	0.593	0.58
777_R	782_Q	0.592	0.58
141_R	144_A	0.592	0.58
576_L	579_S	0.592	0.58
328_A	976_Y	0.592	0.58
363_F	606_V	0.592	0.58
791_S	794_R	0.592	0.58
814_K	819_F	0.591	0.58
382_P	386_F	0.590	0.58
8_G	42_Q	0.590	0.58
43_M	239_K	0.590	0.58
827_G	831_H	0.589	0.58
45_F	49_Y	0.589	0.58
356_K	389_S	0.588	0.58
467_E	475_N	0.588	0.58
805_H	816_R	0.588	0.58
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172_M	176_L	0.588	0.58
18_I	37_F	0.587	0.58
297_Y	305_Y	0.587	0.58
433_C	437_G	0.587	0.58
39_V	241_S	0.587	0.58
510_E	824_P	0.586	0.58
910_V	948_K	0.586	0.58
788_I	791_S	0.585	0.57
51_L	519_D	0.585	0.57
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715_Y	723_Q	0.584	0.57
958_R	1002_T	0.584	0.57
730_L	735_R	0.584	0.57
212_Q	234_S	0.584	0.57
96_L	100_I	0.584	0.57
239_K	604_T	0.583	0.57
69_S	220_V	0.583	0.57
508_Y	905_K	0.583	0.57
952_S	1001_A	0.583	0.57
272_D	660_S	0.583	0.57
652_F	656_M	0.583	0.57
325_E	329_R	0.582	0.57
477_T	480_W	0.582	0.57
313_T	317_A	0.582	0.57
274_T	663_D	0.581	0.57
834_L	889_L	0.581	0.57
42_Q	46_L	0.580	0.57
436_Y	439_K	0.579	0.57
559_E	576_L	0.579	0.57
117_S	120_T	0.579	0.57
939_L	984_T	0.578	0.57
213_F	946_V	0.577	0.56
684_I	705_E	0.576	0.56
686_K	693_P	0.576	0.56
183_S	282_E	0.575	0.56
543_A	576_L	0.574	0.56
801_C	811_L	0.574	0.56
569_I	575_S	0.574	0.56
487_Q	507_R	0.573	0.56
882_H	886_K	0.573	0.56
293_L	299_A	0.573	0.56
275_Y	306_A	0.573	0.56
838_S	914_L	0.572	0.56
435_A	438_I	0.572	0.56
328_A	332_H	0.572	0.56
883_Y	894_T	0.571	0.56
313_T	666_Y	0.571	0.56
688_L	700_L	0.571	0.56
627_D	630_E	0.571	0.56
68_F	207_V	0.571	0.56
864_V	881_R	0.571	0.56
236_T	652_F	0.570	0.55
8_G	235_L	0.570	0.55
63_A	185_D	0.570	0.55
986_L	1006_V	0.570	0.55
207_V	661_P	0.569	0.55
271_L	602_S	0.569	0.55
684_I	689_E	0.568	0.55
381_H	605_F	0.568	0.55
249_L	277_E	0.568	0.55
265_K	269_L	0.568	0.55
271_L	274_T	0.568	0.55
256_G	259_Y	0.567	0.55
11_G	15_T	0.567	0.55
715_Y	722_A	0.566	0.55
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391_L	562_L	0.566	0.55
35_I	659_S	0.566	0.55
721_V	724_S	0.565	0.55
403_V	444_T	0.564	0.55
236_T	656_M	0.563	0.55
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669_Y	685_V	0.562	0.54
412_L	478_R	0.562	0.54
212_Q	348_L	0.562	0.54
39_V	594_D	0.562	0.54
212_Q	241_S	0.561	0.54
560_I	564_L	0.561	0.54
230_H	237_A	0.561	0.54
975_Y	979_A	0.561	0.54
23_Q	26_L	0.561	0.54
681_P	684_I	0.560	0.54
744_W	750_L	0.560	0.54
99_L	171_Q	0.560	0.54
893_V	897_S	0.560	0.54
247_H	397_N	0.560	0.54
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39_V	212_Q	0.559	0.54
290_L	295_A	0.559	0.54
387_I	541_W	0.558	0.54
22_I	37_F	0.558	0.54
305_Y	308_K	0.558	0.54
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212_Q	594_D	0.557	0.54
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96_L	124_E	0.556	0.54
700_L	705_E	0.556	0.54
183_S	187_L	0.555	0.54
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438_I	441_D	0.555	0.54
356_K	359_V	0.555	0.54
564_L	567_Q	0.555	0.54
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374_G	653_L	0.554	0.53
750_L	757_L	0.554	0.53
69_S	72_A	0.553	0.53
67_S	234_S	0.553	0.53
8_G	239_K	0.552	0.53
520_Q	523_Q	0.552	0.53
476_D	480_W	0.552	0.53
468_I	472_N	0.551	0.53
889_L	893_V	0.551	0.53
837_I	982_M	0.551	0.53
592_N	598_M	0.551	0.53
715_Y	720_S	0.551	0.53
330_E	668_S	0.550	0.53
36_I	205_I	0.550	0.53
687_R	704_P	0.550	0.53
440_G	444_T	0.550	0.53
137_P	141_R	0.549	0.53
328_A	363_F	0.549	0.53
349_A	942_R	0.548	0.53
36_I	75_V	0.548	0.53
114_S	120_T	0.548	0.53
690_E	694_H	0.547	0.52
389_S	775_L	0.547	0.52
854_E	950_E	0.547	0.52
209_G	234_S	0.546	0.52
560_I	590_V	0.546	0.52
295_A	300_R	0.546	0.52
582_P	587_Q	0.546	0.52
688_L	696_K	0.546	0.52
565_F	572_G	0.545	0.52
693_P	701_T	0.545	0.52
316_Q	322_A	0.545	0.52
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562_L	568_M	0.543	0.52
982_M	1004_A	0.543	0.52
166_S	170_Q	0.542	0.52
207_V	221_L	0.542	0.52
714_M	723_Q	0.541	0.52
185_D	655_Y	0.541	0.52
312_L	317_A	0.541	0.52
8_G	13_G	0.541	0.52
317_A	322_A	0.540	0.52
958_R	1003_P	0.540	0.52
949_A	1005_G	0.540	0.52
348_L	597_R	0.540	0.52
217_E	598_M	0.539	0.51
140_I	166_S	0.539	0.51
834_L	893_V	0.539	0.51
853_K	887_E	0.538	0.51
150_S	154_G	0.538	0.51
795_M	918_F	0.538	0.51
627_D	632_L	0.538	0.51
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289_E	298_E	0.538	0.51
272_D	282_E	0.537	0.51
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880_N	883_Y	0.536	0.51
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416_N	876_L	0.534	0.51
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691_L	696_K	0.533	0.51
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763_F	768_F	0.532	0.51
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779_V	785_G	0.532	0.51
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285_T	288_P	0.532	0.51
371_F	583_P	0.531	0.50
394_L	974_V	0.530	0.50
484_P	511_E	0.530	0.50
311_A	316_Q	0.530	0.50
736_E	743_W	0.530	0.50
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389_S	392_D	0.525	0.50
594_D	660_S	0.525	0.50
630_E	633_K	0.524	0.49
130_F	165_L	0.524	0.49
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789_Q	938_E	0.522	0.49
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179_Q	792_V	0.522	0.49
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723_Q	735_R	0.522	0.49
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830_F	987_D	0.521	0.49
810_G	816_R	0.521	0.49
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451_Y	472_N	0.519	0.49
835_K	914_L	0.519	0.49
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597_R	659_S	0.516	0.48
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558_D	562_L	0.516	0.48
969_L	1008_Y	0.516	0.48
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187_L	220_V	0.516	0.48
293_L	296_Q	0.515	0.48
616_A	620_E	0.514	0.48
497_T	500_E	0.514	0.48
632_L	638_E	0.514	0.48
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239_K	597_R	0.513	0.48
119_F	937_M	0.513	0.48
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759_S	766_L	0.513	0.48
415_L	478_R	0.513	0.48
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211_Y	599_Y	0.511	0.48
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837_I	893_V	0.511	0.48
10_S	660_S	0.510	0.48
312_L	490_K	0.510	0.48
242_Y	599_Y	0.510	0.48
729_Q	732_L	0.509	0.48
127_L	134_C	0.509	0.48
14_K	208_D	0.508	0.47
684_I	697_E	0.508	0.47
804_S	814_K	0.508	0.47
360_K	370_Y	0.507	0.47
313_T	603_C	0.507	0.47
543_A	547_L	0.507	0.47
243_E	627_D	0.506	0.47
67_S	212_Q	0.506	0.47
348_L	657_A	0.506	0.47
561_S	568_M	0.506	0.47
89_S	128_T	0.506	0.47
244_R	251_L	0.506	0.47
793_S	797_T	0.505	0.47
182_H	185_D	0.505	0.47
597_R	652_F	0.505	0.47
239_K	600_G	0.504	0.47
616_A	646_R	0.504	0.47
43_M	656_M	0.504	0.47
200_I	203_A	0.504	0.47
272_D	656_M	0.504	0.47
8_G	655_Y	0.503	0.47
596_S	660_S	0.502	0.47
1001_A	1005_G	0.502	0.47
75_V	701_T	0.502	0.47
770_N	776_E	0.502	0.47
290_L	297_Y	0.501	0.46
521_E	537_H	0.501	0.46
861_Y	865_E	0.500	0.46
751_M	757_L	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3u4qA	1	0.7564	100	0.521	Contact Map
1w36B	1	0.7642	100	0.565	Contact Map
1pjrA	1	0.5	100	0.612	Contact Map
4c2tA	1	0.524	100	0.614	Contact Map
1uaaA	2	0.5206	100	0.621	Contact Map
4c2uA	1	0.5283	100	0.633	Contact Map
3lfuA	1	0.512	100	0.633	Contact Map
1w36C	1	0.837	100	0.729	Contact Map
4pj3A	1	0.4091	100	0.835	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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