GREMLIN Database
YLXG - FlaA locus uncharacterized protein YlxG
UniProt: P23455 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 140 (126)
Sequences: 1992 (1539)
Seq/√Len: 137.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
47_D50_E4.3591.00
25_G28_E3.5581.00
41_D44_N3.2541.00
128_S131_N2.9811.00
24_L28_E2.7051.00
64_M67_L2.6121.00
94_W127_I2.5191.00
67_L71_M2.3861.00
92_V107_V2.2581.00
60_S64_M2.2031.00
53_S57_T2.1491.00
26_K62_E2.0841.00
27_D31_K2.0481.00
44_N47_D1.8581.00
109_S120_V1.8551.00
57_T60_S1.7941.00
63_Q68_N1.7461.00
75_V78_Q1.7411.00
37_V51_F1.7041.00
50_E53_S1.6931.00
91_E106_T1.6281.00
94_W103_K1.6031.00
105_G121_L1.6011.00
111_K126_E1.5991.00
61_L64_M1.5851.00
26_K66_N1.5591.00
85_V135_V1.4831.00
93_S102_D1.4701.00
93_S134_S1.4441.00
84_Y129_P1.4271.00
81_F112_H1.4201.00
30_L34_M1.4201.00
119_L132_V1.4151.00
53_S58_F1.3981.00
113_F116_N1.3791.00
53_S56_A1.3711.00
112_H117_Y1.3661.00
52_I58_F1.2781.00
56_A61_L1.2501.00
83_T87_W1.2461.00
59_S62_E1.2401.00
48_D51_F1.2361.00
91_E104_T1.2011.00
71_M74_F1.2011.00
51_F58_F1.1841.00
43_L51_F1.1800.99
44_N48_D1.1720.99
32_I84_Y1.1670.99
46_I49_K1.1530.99
10_L13_K1.1530.99
10_L14_T1.1400.99
93_S104_T1.1390.99
120_V126_E1.1340.99
13_K17_V1.1230.99
87_W119_L1.1210.99
28_E31_K1.1060.99
62_E66_N1.1010.99
67_L70_T1.0990.99
118_Y128_S1.0960.99
118_Y126_E1.0770.99
33_L52_I1.0680.99
60_S67_L1.0680.99
35_T38_Q1.0290.99
69_T72_T1.0240.99
121_L124_G1.0130.98
11_P14_T1.0040.98
48_D55_M0.9900.98
34_M38_Q0.9870.98
107_V119_L0.9720.98
92_V121_L0.9620.98
35_T39_N0.9570.98
27_D69_T0.9470.98
15_N18_S0.9390.97
22_S25_G0.9270.97
52_I55_M0.9210.97
81_F85_V0.9150.97
26_K63_Q0.9010.97
119_L129_P0.8900.96
60_S63_Q0.8720.96
64_M71_M0.8710.96
26_K65_M0.8640.96
25_G58_F0.8550.96
37_V49_K0.8500.95
12_E15_N0.8380.95
65_M69_T0.8300.95
74_F79_D0.8200.94
40_Q45_P0.8190.94
105_G122_D0.8060.94
81_F84_Y0.8030.94
106_T122_D0.8010.94
82_T85_V0.7810.93
111_K120_V0.7740.93
43_L48_D0.7560.92
121_L126_E0.7530.92
74_F78_Q0.7520.91
105_G123_D0.7480.91
28_E33_L0.7440.91
25_G56_A0.7380.91
25_G51_F0.7360.91
84_Y117_Y0.7280.90
24_L52_I0.7230.90
84_Y110_V0.7220.90
32_I45_P0.7210.90
108_S120_V0.7190.90
67_L74_F0.7180.90
39_N44_N0.7130.89
28_E55_M0.7110.89
31_K38_Q0.7110.89
85_V88_M0.7110.89
14_T17_V0.7110.89
26_K64_M0.7090.89
116_N130_A0.7090.89
99_S102_D0.7050.89
11_P15_N0.7050.89
17_V72_T0.6970.88
36_Q56_A0.6960.88
26_K58_F0.6940.88
47_D51_F0.6810.87
48_D52_I0.6810.87
18_S21_N0.6780.87
127_I132_V0.6770.87
87_W129_P0.6710.86
49_K52_I0.6650.86
102_D133_M0.6610.85
108_S118_Y0.6590.85
81_F88_M0.6590.85
16_T21_N0.6580.85
14_T19_T0.6580.85
26_K55_M0.6560.85
25_G65_M0.6490.84
19_T22_S0.6490.84
52_I60_S0.6480.84
63_Q66_N0.6410.83
98_K101_T0.6390.83
75_V79_D0.6380.83
13_K16_T0.6350.83
32_I52_I0.6330.83
116_N128_S0.6310.83
51_F59_S0.6300.82
108_S122_D0.6270.82
19_T23_S0.6260.82
34_M55_M0.6210.82
35_T46_I0.6170.81
26_K34_M0.6140.81
10_L17_V0.6140.81
50_E57_T0.6140.81
87_W92_V0.6130.81
55_M59_S0.6090.80
82_T129_P0.6080.80
49_K53_S0.6080.80
26_K46_I0.6060.80
58_F63_Q0.5980.79
53_S102_D0.5980.79
73_Q77_N0.5910.78
27_D34_M0.5910.78
58_F70_T0.5840.77
127_I133_M0.5770.77
103_K125_T0.5760.76
36_Q45_P0.5740.76
37_V109_S0.5740.76
36_Q57_T0.5730.76
110_V119_L0.5730.76
51_F55_M0.5650.75
70_T75_V0.5580.74
87_W132_V0.5570.74
81_F111_K0.5480.73
51_F63_Q0.5430.72
51_F61_L0.5420.72
56_A59_S0.5400.72
22_S26_K0.5400.72
82_T88_M0.5370.71
66_N72_T0.5370.71
30_L51_F0.5360.71
69_T73_Q0.5270.70
16_T19_T0.5260.70
32_I48_D0.5260.70
107_V135_V0.5230.69
52_I97_G0.5180.69
66_N69_T0.5180.69
22_S28_E0.5150.68
85_V90_K0.5140.68
95_T99_S0.5130.68
56_A60_S0.5060.67
111_K117_Y0.5060.67
30_L63_Q0.5060.67
33_L55_M0.5050.67
109_S134_S0.5040.67
71_M75_V0.5020.66
17_V20_N0.5000.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3c12A 2 0.4143 96.8 0.824 Contact Map
3osvA 2 0.6357 94.8 0.85 Contact Map
4a53A 1 0.4429 27.2 0.921 Contact Map
2vc8A 1 0.4 23 0.924 Contact Map
3htrA 2 0.45 11.1 0.934 Contact Map
1vt0M 4 0.4357 10.4 0.935 Contact Map
2vxeA 1 0.3786 9.8 0.936 Contact Map
2wacA 1 0.7357 9.4 0.937 Contact Map
2g3rA 2 0.3786 8.5 0.938 Contact Map
1pm3A 2 0.3929 7.6 0.939 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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