GREMLIN Database
FLIL - Flagellar protein FliL
UniProt: P23452 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 140 (137)
Sequences: 1324 (1050)
Seq/√Len: 89.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
6_M10_L3.7251.00
98_T115_E3.2001.00
21_A25_F3.1541.00
19_L23_A2.9751.00
20_G23_A2.6881.00
8_I12_I2.6701.00
74_D78_E2.6051.00
64_R136_S2.5811.00
89_D113_K2.3641.00
99_N102_Q2.3001.00
7_I11_I2.2511.00
96_A109_K2.1601.00
78_E81_E2.1211.00
70_E86_Q2.1191.00
20_G24_Y2.1121.00
75_K78_E2.0401.00
22_A26_V1.9511.00
15_V19_L1.9511.00
119_K122_S1.8971.00
23_A27_L1.8541.00
83_R86_Q1.8431.00
69_L120_I1.8021.00
48_V71_T1.7551.00
98_T102_Q1.7361.00
55_T63_I1.7241.00
16_I20_G1.7181.00
91_V116_L1.6781.00
17_G21_A1.6591.00
24_Y28_G1.6161.00
10_L13_L1.5841.00
9_L12_I1.5781.00
5_L9_L1.5691.00
121_N127_G1.4961.00
8_I11_I1.4891.00
14_I17_G1.4781.00
95_L116_L1.4721.00
77_K81_E1.4540.99
50_V88_K1.3740.99
89_D93_S1.3580.99
18_A22_A1.3520.99
53_I88_K1.3150.99
51_E88_K1.2970.99
114_K118_D1.2870.99
57_L89_D1.2770.99
54_T64_R1.2480.98
67_I116_L1.2420.98
117_K132_V1.2010.98
48_V77_K1.2000.98
134_I137_F1.1800.98
22_A25_F1.1620.97
74_D77_K1.1580.97
94_L116_L1.1380.97
50_V87_V1.1340.97
124_L127_G1.1120.97
79_E127_G1.1070.96
78_E82_K1.1050.96
49_D68_K1.0960.96
22_A28_G1.0920.96
47_S83_R1.0920.96
109_K137_F1.0910.96
13_L16_I1.0810.96
10_L17_G1.0650.96
15_V18_A1.0560.95
103_I139_L1.0450.95
4_K8_I1.0430.95
79_E83_R1.0390.95
91_V95_L1.0370.95
55_T95_L1.0170.94
52_E64_R1.0030.94
63_I95_L0.9850.93
67_I134_I0.9780.93
50_V84_D0.9650.93
70_E130_E0.9560.92
7_I26_V0.9360.91
106_D110_E0.9320.91
12_I19_L0.9270.91
21_A24_Y0.9180.91
48_V81_E0.9120.90
116_L120_I0.9040.90
116_L132_V0.9020.90
25_F29_G0.9010.90
45_A83_R0.9010.90
24_Y29_G0.8990.90
19_L22_A0.8890.89
13_L17_G0.8690.88
81_E84_D0.8640.88
47_S85_F0.8510.87
71_T85_F0.8500.87
76_S79_E0.8460.87
52_E63_I0.8410.86
34_S37_K0.8400.86
96_A105_G0.8300.86
90_A123_Y0.8250.85
64_R138_N0.8190.85
88_K92_I0.8170.85
110_E114_K0.8070.84
110_E113_K0.8040.84
72_D130_E0.8010.84
108_G137_F0.7960.83
11_I18_A0.7650.81
63_I104_E0.7610.80
10_L14_I0.7610.80
35_E38_K0.7560.80
65_L134_I0.7550.80
4_K7_I0.7450.79
107_K110_E0.7450.79
72_D91_V0.7430.79
62_I139_L0.7410.79
39_S42_E0.7400.79
61_N138_N0.7390.78
102_Q132_V0.7310.78
76_S128_K0.7240.77
92_I96_A0.7190.77
94_L98_T0.7150.76
11_I15_V0.7130.76
80_L87_V0.7090.76
7_I18_A0.7050.75
113_K131_K0.7030.75
28_G33_K0.7000.75
61_N100_A0.6990.75
45_A64_R0.6980.74
18_A21_A0.6970.74
14_I18_A0.6920.74
135_T138_N0.6920.74
30_K35_E0.6880.73
51_E68_K0.6880.73
86_Q133_Y0.6830.73
97_D106_D0.6810.73
16_I32_E0.6750.72
105_G108_G0.6740.72
93_S109_K0.6720.72
31_S34_S0.6680.71
43_I54_T0.6630.71
52_E66_A0.6630.71
5_L10_L0.6580.70
57_L100_A0.6570.70
4_K21_A0.6550.70
118_D122_S0.6480.69
16_I23_A0.6460.69
66_A89_D0.6450.68
50_V69_L0.6450.68
70_E131_K0.6400.68
120_I129_V0.6390.68
66_A136_S0.6370.68
16_I19_L0.6360.67
70_E89_D0.6350.67
11_I14_I0.6330.67
87_V120_I0.6300.67
22_A35_E0.6300.67
116_L135_T0.6250.66
45_A70_E0.6250.66
84_D118_D0.6220.66
24_Y27_L0.6220.66
90_A119_K0.6210.66
62_I111_T0.6160.65
57_L60_D0.6150.65
71_T76_S0.6070.64
54_T113_K0.6060.64
100_A139_L0.6050.64
93_S110_E0.6010.63
99_N111_T0.6010.63
57_L139_L0.5990.63
104_E109_K0.5970.63
113_K133_Y0.5960.62
47_S68_K0.5870.61
46_S74_D0.5840.61
89_D133_Y0.5750.60
10_L24_Y0.5720.59
111_T114_K0.5710.59
89_D109_K0.5710.59
32_E35_E0.5700.59
121_N124_L0.5650.58
12_I15_V0.5620.58
16_I36_A0.5610.58
49_D69_L0.5580.57
60_D139_L0.5570.57
4_K22_A0.5560.57
87_V123_Y0.5540.57
47_S133_Y0.5530.57
108_G134_I0.5530.57
34_S38_K0.5460.56
48_V80_L0.5450.56
8_I26_V0.5390.55
47_S86_Q0.5380.55
76_S124_L0.5340.54
6_M13_L0.5330.54
48_V84_D0.5320.54
9_L13_L0.5310.54
33_K38_K0.5290.53
71_T138_N0.5250.53
53_I98_T0.5230.53
27_L33_K0.5210.52
89_D92_I0.5180.52
13_L20_G0.5150.52
111_T130_E0.5140.51
63_I98_T0.5140.51
101_D122_S0.5130.51
35_E40_I0.5130.51
111_T115_E0.5110.51
92_I135_T0.5080.51
53_I64_R0.5070.50
54_T96_A0.5040.50
35_E78_E0.5030.50
16_I105_G0.5030.50
62_I115_E0.5000.49
4_K11_I0.5000.49
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zg1A 2 0.5714 81.7 0.882 Contact Map
3ne5B 3 0.45 59.6 0.9 Contact Map
3bk6A 3 0.7786 33.1 0.915 Contact Map
3j6da 3 0 29.8 0.917 Contact Map
3b55A 1 0.65 27.8 0.918 Contact Map
2rpbA 1 0.7286 24.6 0.92 Contact Map
2qgmA 1 0.6643 23.2 0.921 Contact Map
1winA 1 0.7429 22.3 0.922 Contact Map
4fvgA 2 0.6786 20.9 0.923 Contact Map
2mfrA 1 0.3071 19.2 0.924 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0062 seconds.