GREMLIN Database
FLGG - Flagellar basal-body rod protein FlgG
UniProt: P23446 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 264 (245)
Sequences: 5700 (4224)
Seq/√Len: 269.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
102_F118_F3.7031.00
94_L153_I3.4101.00
154_G158_K3.3191.00
188_I194_R3.1751.00
121_D125_T3.1201.00
112_Y179_F3.0491.00
85_T220_F3.0021.00
128_T132_Y2.9991.00
125_T133_H2.9411.00
103_R177_V2.8181.00
85_T95_A2.7771.00
161_I171_G2.7491.00
99_D178_T2.5431.00
186_D194_R2.4751.00
217_K220_F2.4221.00
158_K170_D2.3601.00
80_H101_Y2.2941.00
106_T111_A2.2671.00
254_E257_Q2.2381.00
186_D196_S2.1571.00
104_I113_T2.1081.00
195_E201_T2.0641.00
106_T110_T2.0521.00
86_Q223_M2.0281.00
36_K231_E2.0151.00
37_S187_K2.0131.00
94_L216_L2.0121.00
111_A188_I2.0111.00
19_L235_M1.9411.00
87_S220_F1.9311.00
18_K238_A1.9311.00
4_S252_S1.9221.00
111_A192_L1.8511.00
26_I228_L1.8281.00
96_I214_G1.8231.00
105_D135_L1.8211.00
115_A191_N1.8151.00
126_L134_V1.8051.00
247_K250_T1.8021.00
154_G160_S1.7861.00
97_D217_K1.7621.00
22_I238_A1.7581.00
104_I128_T1.7431.00
160_S170_D1.7371.00
96_I176_I1.7281.00
18_K234_E1.7191.00
181_N184_G1.7021.00
106_T109_G1.6941.00
19_L238_A1.6791.00
230_D234_E1.6441.00
121_D127_V1.6381.00
14_N71_S1.6261.00
148_A161_I1.6261.00
153_I159_V1.6021.00
227_D230_D1.5871.00
92_L151_F1.5871.00
118_F134_V1.5371.00
88_T93_D1.5281.00
32_V221_L1.5111.00
99_D182_S1.4961.00
179_F195_E1.4921.00
125_T143_K1.4671.00
155_S215_A1.4531.00
32_V115_A1.4401.00
111_A194_R1.4351.00
234_E237_V1.4251.00
107_G132_Y1.3971.00
41_F45_V1.3961.00
22_I235_M1.3941.00
136_N175_G1.3691.00
21_V39_V1.3691.00
8_G248_I1.3681.00
15_F241_G1.3651.00
16_Q20_D1.3601.00
78_T187_K1.3571.00
115_A129_G1.3501.00
106_T132_Y1.3471.00
94_L102_F1.3461.00
84_A223_M1.3411.00
231_E234_E1.3171.00
158_K173_Q1.3041.00
250_T253_D1.3001.00
94_L174_I1.2911.00
29_V228_L1.2851.00
103_R135_L1.2831.00
36_K230_D1.2701.00
36_K79_I1.2661.00
92_L126_L1.2641.00
137_M173_Q1.2371.00
17_T73_S1.2231.00
178_T213_T1.2211.00
188_I192_L1.2101.00
90_R93_D1.2001.00
32_V117_N1.1931.00
37_S78_T1.1891.00
209_G215_A1.1871.00
101_Y182_S1.1791.00
132_Y192_L1.1771.00
104_I118_F1.1731.00
139_G142_I1.1631.00
24_N34_F1.1601.00
195_E199_S1.1541.00
39_V73_S1.1541.00
149_Q164_A1.1481.00
144_I148_A1.1401.00
80_H193_Y1.1391.00
104_I192_L1.1211.00
104_I111_A1.1111.00
38_R77_D1.1001.00
94_L218_S1.0981.00
34_F37_S1.0911.00
128_T134_V1.0911.00
146_T164_A1.0901.00
184_G196_S1.0721.00
257_Q261_N1.0381.00
199_S202_A1.0331.00
253_D256_L1.0261.00
136_N172_G1.0151.00
11_G245_N1.0141.00
130_D190_S1.0061.00
92_L120_L0.9941.00
38_R79_I0.9941.00
15_F238_A0.9881.00
136_N142_I0.9841.00
103_R175_G0.9811.00
22_I231_E0.9791.00
97_D215_A0.9751.00
240_R243_Q0.9691.00
15_F18_K0.9621.00
150_S162_V0.9571.00
176_I214_G0.9541.00
179_F185_L0.9521.00
66_Q187_K0.9511.00
196_S199_S0.9511.00
163_D166_G0.9501.00
112_Y202_A0.9491.00
19_L255_I0.9371.00
155_S217_K0.9351.00
160_S168_T0.9131.00
94_L118_F0.9121.00
162_V168_T0.9111.00
21_V34_F0.9021.00
162_V166_G0.9021.00
25_N231_E0.8971.00
256_L260_V0.8911.00
91_T150_S0.8901.00
18_K22_I0.8881.00
187_K193_Y0.8831.00
135_L141_T0.8791.00
137_M175_G0.8771.00
96_I102_F0.8751.00
95_A220_F0.8681.00
176_I213_T0.8651.00
145_P161_I0.8601.00
2_L256_L0.8541.00
90_R119_Y0.8461.00
9_I12_M0.8431.00
134_V174_I0.8330.99
105_D133_H0.8320.99
179_F202_A0.8250.99
145_P148_A0.8220.99
36_K225_N0.8190.99
208_P216_L0.8190.99
229_T232_F0.8140.99
19_L239_Q0.8130.99
146_T165_E0.8090.99
119_Y129_G0.8090.99
93_D117_N0.8040.99
48_T51_G0.8010.99
232_F250_T0.7860.99
143_K167_K0.7840.99
96_I100_G0.7790.99
102_F174_I0.7780.99
117_N129_G0.7760.99
41_F44_M0.7720.99
163_D169_Q0.7700.99
240_R253_D0.7690.99
133_H141_T0.7670.99
23_G248_I0.7670.99
11_G15_F0.7640.99
250_T254_E0.7630.99
126_L142_I0.7630.99
85_T217_K0.7610.99
44_M48_T0.7600.99
113_T128_T0.7490.99
165_E168_T0.7470.99
32_V223_M0.7450.99
18_K237_V0.7440.99
209_G212_G0.7410.99
43_D46_S0.7400.99
3_R69_L0.7370.99
139_G175_G0.7350.99
12_M246_S0.7330.99
251_T254_E0.7260.99
127_V133_H0.7140.98
5_L249_I0.7110.98
42_K72_S0.7080.98
143_K146_T0.7070.98
252_S255_I0.7060.98
8_G249_I0.7050.98
82_T97_D0.7040.98
13_K227_D0.7020.98
126_L174_I0.7020.98
226_V231_E0.7010.98
128_T192_L0.7010.98
100_G214_G0.6990.98
40_T77_D0.6980.98
142_I146_T0.6980.98
249_I253_D0.6940.98
258_E261_N0.6930.98
70_G73_S0.6930.98
172_G175_G0.6910.98
178_T182_S0.6900.98
228_L243_Q0.6880.98
8_G245_N0.6870.98
242_F246_S0.6860.98
250_T257_Q0.6850.98
105_D108_D0.6800.98
148_A164_A0.6780.98
149_Q162_V0.6750.98
16_Q242_F0.6750.98
10_S14_N0.6730.98
4_S248_I0.6720.98
46_S68_G0.6670.98
172_G177_V0.6660.98
159_V172_G0.6640.97
137_M142_I0.6640.97
38_R41_F0.6630.97
40_T44_M0.6610.97
2_L255_I0.6600.97
209_G214_G0.6590.97
176_I179_F0.6580.97
188_I191_N0.6520.97
52_G64_S0.6510.97
231_E239_Q0.6490.97
138_N142_I0.6480.97
4_S7_S0.6460.97
156_D173_Q0.6440.97
94_L134_V0.6430.97
163_D167_K0.6430.97
181_N185_L0.6390.97
243_Q247_K0.6380.97
174_I216_L0.6380.97
146_T170_D0.6360.97
120_L126_L0.6360.97
86_Q221_L0.6360.97
121_D133_H0.6320.97
229_T237_V0.6300.97
40_T75_T0.6300.97
146_T161_I0.6300.97
141_T144_I0.6300.97
142_I145_P0.6250.96
255_I259_L0.6230.96
211_G214_G0.6230.96
104_I134_V0.6180.96
68_G76_I0.6180.96
147_D163_D0.6140.96
125_T141_T0.6130.96
184_G200_G0.6130.96
91_T218_S0.6120.96
42_K74_G0.6120.96
246_S255_I0.6110.96
113_T116_G0.6100.96
142_I172_G0.6090.96
7_S70_G0.6070.96
248_I252_S0.6060.96
49_I52_G0.6030.96
13_K230_D0.6020.96
96_I216_L0.5990.95
5_L256_L0.5990.95
117_N221_L0.5980.95
14_N41_F0.5970.95
104_I132_Y0.5970.95
138_N172_G0.5970.95
100_G114_R0.5950.95
152_S162_V0.5940.95
12_M15_F0.5930.95
172_G176_I0.5920.95
6_Y237_V0.5900.95
209_G213_T0.5890.95
154_G170_D0.5890.95
34_F38_R0.5890.95
251_T255_I0.5880.95
151_F161_I0.5870.95
82_T85_T0.5860.95
100_G176_I0.5840.95
247_K258_E0.5820.95
107_G110_T0.5820.95
179_F200_G0.5810.95
47_Q69_L0.5810.95
232_F258_E0.5800.95
136_N139_G0.5780.94
17_T21_V0.5780.94
101_Y193_Y0.5770.94
170_D173_Q0.5730.94
102_F116_G0.5710.94
139_G172_G0.5710.94
184_G199_S0.5700.94
173_Q176_I0.5700.94
155_S159_V0.5690.94
90_R221_L0.5660.94
21_V73_S0.5650.94
178_T203_S0.5600.93
196_S200_G0.5600.93
105_D109_G0.5590.93
21_V76_I0.5580.93
184_G198_N0.5560.93
48_T66_Q0.5560.93
49_I53_S0.5560.93
3_R20_D0.5550.93
13_K17_T0.5540.93
94_L219_G0.5540.93
239_Q246_S0.5540.93
96_I101_Y0.5530.93
108_D111_A0.5530.93
103_R112_Y0.5520.93
119_Y122_N0.5500.93
15_F233_T0.5490.93
177_V180_A0.5480.93
248_I251_T0.5480.93
144_I171_G0.5480.93
103_R174_I0.5480.93
7_S12_M0.5470.93
48_T52_G0.5460.93
244_S248_I0.5450.93
5_L11_G0.5410.92
237_V256_L0.5400.92
82_T98_G0.5400.92
33_G193_Y0.5390.92
25_N34_F0.5370.92
112_Y116_G0.5360.92
247_K251_T0.5360.92
105_D141_T0.5350.92
142_I163_D0.5340.92
106_T133_H0.5320.92
91_T219_G0.5320.92
243_Q250_T0.5320.92
180_A183_D0.5300.91
175_G179_F0.5300.91
149_Q161_I0.5290.91
174_I177_V0.5280.91
118_F129_G0.5280.91
9_I15_F0.5270.91
167_K170_D0.5260.91
153_I218_S0.5250.91
253_D257_Q0.5240.91
82_T114_R0.5230.91
7_S20_D0.5230.91
243_Q246_S0.5220.91
242_F255_I0.5200.91
102_F153_I0.5180.91
146_T163_D0.5170.90
175_G180_A0.5160.90
159_V171_G0.5120.90
39_V76_I0.5110.90
43_D68_G0.5110.90
189_G192_L0.5100.90
236_I239_Q0.5100.90
244_S247_K0.5090.90
142_I159_V0.5070.90
52_G66_Q0.5060.90
141_T146_T0.5050.89
135_L175_G0.5050.89
210_D215_A0.5050.89
121_D124_G0.5050.89
246_S259_L0.5030.89
32_V86_Q0.5000.89
102_F114_R0.5000.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3a69A 3 0.7083 100 0.103 Contact Map
1wlgA 2 0.5038 100 0.562 Contact Map
4ut1A 1 0.5189 99.7 0.725 Contact Map
1oryB 2 0.1515 15.9 0.958 Contact Map
2x5pA 1 0.3788 9.4 0.962 Contact Map
3j9aA 1 0.2159 4.5 0.967 Contact Map
2m4eA 1 0.072 2.6 0.971 Contact Map
2jujA 1 0.1629 1.8 0.973 Contact Map
4dwlA 3 0.1136 1.8 0.973 Contact Map
4g35B 1 0.0152 1.7 0.974 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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