ODO1 - BACSU - GREMLIN Contacts

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ODO1 - 2-oxoglutarate dehydrogenase E1 component

UniProt:	P23129	Sequences: MFQNSMKQRMNWEDFYGPNLGYALELYDQYTQDPNSIDPDLKEMFDELGAPPSDIKEASGTKEKGRVTADLIQKIASAVRLAEDIRTYGHLNASVNPLRKDEKKSELFPLSDYGLTEEEIKAIPASVICKDAPKNISNGLEAIQYLRNTYKRTISFEFDHVHDFKEREWLTRKIESGELFQKNSAEKLSAVLERLTEVEGFEQFLHRTFVGQKRFSIEGLDALVPVLDDIIAQSVKSGTTSVNIGMAHRGRLNVLAHVLGKPYEIIFSEFQHAPNKDLVPSEGSIGISYGWTGDVKYHLGANRELQDAETKSARITLANNPSHLEFINPIVEGSTRAAQETRTQSGYPVQDETKSLAILIHGDAAFPGEGIVAETLNLSSLKGYQVGGAIHIIANNMIGFTTESAESRSTKYASDLAKGYEIPIVHVNADDPEACLSAVKFAVEYRKTFNKDFLIDLIGYRRYGHNEMDEPSTTQPMLYDAVRKHPTVKQIFAEKLVKEGVVTEEVVQNIEKSVTKRIEDAYQKVPSKKEHTACEIELPEPVSNGFPDVDTSIDFDVLRKLNGELINWPESFNVFGKLKRILERRAKAFDDDRKVEWSLAESLAFASILKDGTPIRLTGQDSERGTFAQRNLVLHDSETGKEFVPLHHLSDCSTSFAVHNSPLSEGSVLGFEYGYNVHSPETLVLWEAQYGDFANAAQVYFDQFISAGRAKWGQKSGLVMLLPHGYEGQGPEHSSGRIERFLQLAAENNWTVANLTSAAQYFHILRRQAKMLLREEIRPLVIMTPKSLLRNPNTVSEVQELSESRFQPVYEQSGLSHDYEKVTRLVLSSGKVSIDISDHFNKLEDGKEWLHIARIEQLYPFPAKGVKELFAKLPNLKEIVWVQEEPQNMGAWGYISPYLTEIAPEGVSVQYIGRRRRSSPAEGDPTVHKKEQERIVSDSLTRKN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	944 (891)
Sequences:	2244 (1162)
Seq/√Len:	38.9

ECOLI - ODO1
BACSU - ODO1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
738_I	783_M	5.190	1.00
121_K	140_L	5.165	1.00
823_T	849_W	4.917	1.00
753_A	764_I	4.777	1.00
669_L	720_M	4.667	1.00
706_S	750_W	4.333	1.00
425_V	438_A	4.234	1.00
256_A	266_I	4.197	1.00
676_N	716_S	4.177	1.00
393_I	414_S	4.146	1.00
694_A	741_F	4.065	1.00
826_V	882_V	4.005	1.00
561_L	606_A	3.829	1.00
701_F	720_M	3.824	1.00
839_H	845_D	3.784	1.00
166_E	451_K	3.572	1.00
745_A	750_W	3.499	1.00
247_A	394_A	3.446	1.00
617_L	658_V	3.404	1.00
869_L	872_K	3.402	1.00
220_L	459_G	3.362	1.00
811_E	869_L	3.313	1.00
173_K	444_E	3.308	1.00
832_V	835_D	3.266	1.00
188_L	499_E	3.253	1.00
425_V	453_F	3.249	1.00
223_L	394_A	3.246	1.00
573_N	638_E	3.174	1.00
504_E	508_Q	3.135	1.00
247_A	360_I	3.079	1.00
480_D	638_E	3.033	1.00
304_E	314_R	3.014	1.00
154_I	438_A	2.965	1.00
240_T	354_K	2.930	1.00
326_F	704_F	2.923	1.00
494_E	498_K	2.892	1.00
185_A	189_S	2.885	1.00
353_T	450_N	2.844	1.00
745_A	752_V	2.804	1.00
932_Q	936_V	2.790	1.00
648_H	653_S	2.776	1.00
553_I	607_S	2.771	1.00
824_R	878_E	2.734	1.00
486_P	494_E	2.708	1.00
821_K	848_E	2.643	1.00
623_E	660_N	2.632	1.00
738_I	891_A	2.628	1.00
555_F	559_R	2.620	1.00
156_F	174_I	2.555	1.00
509_N	513_S	2.544	1.00
934_R	938_D	2.542	1.00
153_T	431_D	2.510	1.00
429_A	459_G	2.479	1.00
332_E	386_V	2.477	1.00
825_L	876_L	2.470	1.00
764_I	782_I	2.457	1.00
166_E	445_Y	2.449	1.00
855_I	858_L	2.441	1.00
490_Q	494_E	2.434	1.00
165_K	448_T	2.432	1.00
705_I	720_M	2.411	1.00
199_E	487_T	2.409	1.00
618_T	668_V	2.407	1.00
230_I	390_I	2.388	1.00
233_Q	444_E	2.382	1.00
855_I	895_I	2.373	1.00
371_I	666_G	2.359	1.00
839_H	842_K	2.345	1.00
818_D	821_K	2.336	1.00
828_S	832_V	2.335	1.00
758_A	795_V	2.329	1.00
738_I	829_S	2.314	1.00
508_Q	512_K	2.299	1.00
925_P	929_K	2.279	1.00
827_L	866_V	2.270	1.00
819_Y	872_K	2.270	1.00
557_V	610_K	2.263	1.00
825_L	870_F	2.255	1.00
850_L	940_L	2.241	0.99
826_V	939_S	2.234	0.99
326_F	700_Y	2.223	0.99
751_T	774_R	2.216	0.99
611_D	770_K	2.210	0.99
431_D	434_A	2.206	0.99
826_V	852_I	2.204	0.99
328_N	359_L	2.203	0.99
721_L	782_I	2.197	0.99
561_L	607_S	2.182	0.99
227_L	254_V	2.176	0.99
378_L	662_P	2.169	0.99
226_V	439_V	2.144	0.99
226_V	392_I	2.114	0.99
838_D	842_K	2.103	0.99
696_A	699_V	2.074	0.99
138_N	141_E	2.074	0.99
832_V	882_V	2.073	0.99
933_E	937_S	2.062	0.99
196_T	489_K	2.058	0.99
670_G	700_Y	2.054	0.99
753_A	782_I	2.037	0.99
473_T	628_A	2.016	0.99
613_T	769_A	1.996	0.99
832_V	935_I	1.987	0.99
614_P	654_T	1.977	0.99
94_S	153_T	1.969	0.99
433_E	492_F	1.968	0.99
30_Y	46_D	1.965	0.99
326_F	666_G	1.953	0.99
226_V	435_C	1.951	0.99
744_L	750_W	1.922	0.98
808_P	865_G	1.920	0.98
839_H	940_L	1.919	0.98
335_T	357_A	1.918	0.98
227_L	360_I	1.914	0.98
720_M	781_V	1.913	0.98
793_N	841_N	1.912	0.98
861_F	895_I	1.906	0.98
709_R	778_R	1.899	0.98
807_Q	810_Y	1.893	0.98
417_A	454_L	1.889	0.98
836_I	852_I	1.886	0.98
503_T	506_V	1.866	0.98
736_G	783_M	1.836	0.98
366_F	454_L	1.831	0.98
187_K	440_K	1.827	0.98
787_S	831_K	1.807	0.98
364_A	399_G	1.805	0.98
685_L	721_L	1.801	0.98
495_K	499_E	1.801	0.98
170_L	425_V	1.791	0.97
124_P	139_G	1.780	0.97
932_Q	935_I	1.780	0.97
553_I	558_L	1.768	0.97
812_Q	815_L	1.767	0.97
752_V	783_M	1.755	0.97
163_D	166_E	1.755	0.97
755_L	764_I	1.745	0.97
878_E	910_Q	1.744	0.97
29_Q	36_S	1.740	0.97
96_N	100_K	1.738	0.97
579_K	583_E	1.736	0.97
600_A	801_L	1.735	0.97
184_S	187_K	1.724	0.97
378_L	667_S	1.719	0.97
785_P	831_K	1.705	0.97
797_E	800_E	1.699	0.96
371_I	667_S	1.695	0.96
831_K	932_Q	1.689	0.96
384_Y	618_T	1.679	0.96
788_L	834_I	1.671	0.96
583_E	586_A	1.665	0.96
302_N	314_R	1.659	0.96
494_E	504_E	1.644	0.96
373_A	620_Q	1.644	0.96
922_E	931_E	1.643	0.96
33_D	36_S	1.640	0.96
896_S	900_T	1.638	0.96
512_K	516_K	1.630	0.96
234_S	443_V	1.629	0.96
605_F	761_Y	1.628	0.95
470_E	473_T	1.626	0.95
635_H	642_E	1.625	0.95
617_L	685_L	1.625	0.95
123_I	136_I	1.624	0.95
837_S	852_I	1.620	0.95
568_W	574_V	1.617	0.95
814_G	841_N	1.615	0.95
552_S	804_S	1.612	0.95
332_E	375_T	1.606	0.95
582_L	634_L	1.604	0.95
855_I	866_V	1.604	0.95
632_L	658_V	1.600	0.95
572_F	634_L	1.592	0.95
485_H	491_I	1.592	0.95
793_N	838_D	1.591	0.95
173_K	448_T	1.578	0.95
42_K	46_D	1.573	0.95
230_I	358_I	1.559	0.94
223_L	392_I	1.557	0.94
302_N	714_Q	1.556	0.94
761_Y	764_I	1.554	0.94
188_L	433_E	1.548	0.94
223_L	360_I	1.548	0.94
430_D	485_H	1.548	0.94
632_L	656_F	1.542	0.94
223_L	254_V	1.529	0.94
583_E	587_K	1.521	0.94
650_S	653_S	1.519	0.93
377_N	662_P	1.507	0.93
78_A	124_P	1.505	0.93
553_I	557_V	1.500	0.93
853_A	869_L	1.497	0.93
369_E	696_A	1.494	0.93
229_D	440_K	1.489	0.93
587_K	592_D	1.487	0.93
98_L	478_L	1.481	0.93
552_S	802_S	1.480	0.93
558_L	798_V	1.478	0.92
563_G	586_A	1.478	0.92
134_K	141_E	1.474	0.92
900_T	908_S	1.474	0.92
731_P	919_S	1.473	0.92
912_I	938_D	1.470	0.92
721_L	784_T	1.467	0.92
364_A	407_S	1.466	0.92
26_L	29_Q	1.464	0.92
373_A	419_G	1.457	0.92
636_D	639_T	1.455	0.92
606_A	610_K	1.451	0.92
376_L	420_Y	1.448	0.92
189_S	506_V	1.443	0.92
727_E	787_S	1.442	0.92
472_S	483_R	1.434	0.91
264_E	521_A	1.432	0.91
378_L	386_V	1.429	0.91
797_E	801_L	1.426	0.91
754_N	884_E	1.425	0.91
745_A	859_Y	1.415	0.91
810_Y	813_S	1.408	0.91
666_G	699_V	1.406	0.90
589_F	599_L	1.404	0.90
811_E	873_L	1.402	0.90
162_H	421_E	1.400	0.90
144_Q	148_N	1.400	0.90
209_F	271_Q	1.400	0.90
588_A	599_L	1.396	0.90
497_V	503_T	1.392	0.90
110_L	120_I	1.383	0.90
561_L	610_K	1.381	0.90
191_V	436_L	1.380	0.90
727_E	831_K	1.378	0.90
845_D	937_S	1.375	0.89
359_L	391_H	1.372	0.89
793_N	837_S	1.371	0.89
887_Q	897_P	1.370	0.89
936_V	940_L	1.370	0.89
929_K	933_E	1.367	0.89
827_L	855_I	1.365	0.89
160_H	424_I	1.362	0.89
673_Y	708_G	1.358	0.89
92_N	147_R	1.354	0.89
602_S	605_F	1.349	0.89
437_S	441_F	1.348	0.89
223_L	457_L	1.346	0.88
669_L	694_A	1.345	0.88
607_S	762_F	1.343	0.88
622_S	658_V	1.339	0.88
563_G	590_D	1.339	0.88
481_A	484_K	1.334	0.88
614_P	682_T	1.330	0.88
194_R	197_E	1.327	0.88
344_Q	352_E	1.327	0.88
869_L	873_L	1.320	0.87
141_E	144_Q	1.319	0.87
225_P	436_L	1.319	0.87
555_F	799_Q	1.318	0.87
111_S	117_E	1.316	0.87
222_A	435_C	1.315	0.87
403_E	660_N	1.314	0.87
206_H	216_S	1.311	0.87
825_L	853_A	1.311	0.87
74_K	115_L	1.305	0.87
633_V	644_V	1.303	0.87
429_A	457_L	1.303	0.87
392_I	457_L	1.294	0.86
201_F	266_I	1.292	0.86
858_L	891_A	1.291	0.86
237_S	443_V	1.290	0.86
74_K	119_E	1.288	0.86
563_G	567_N	1.286	0.86
342_R	355_S	1.285	0.86
822_V	873_L	1.281	0.86
706_S	744_L	1.280	0.86
882_V	939_S	1.276	0.86
331_V	359_L	1.271	0.85
240_T	311_K	1.268	0.85
754_N	829_S	1.268	0.85
422_I	454_L	1.266	0.85
595_V	797_E	1.265	0.85
153_T	434_A	1.262	0.85
220_L	429_A	1.259	0.85
197_E	517_R	1.248	0.84
828_S	852_I	1.248	0.84
230_I	439_V	1.246	0.84
833_S	837_S	1.246	0.84
826_V	880_V	1.245	0.84
831_K	884_E	1.244	0.84
755_L	760_Q	1.241	0.84
613_T	770_K	1.238	0.84
595_V	599_L	1.235	0.84
261_K	269_E	1.233	0.84
516_K	520_D	1.233	0.84
694_A	701_F	1.230	0.83
887_Q	916_R	1.229	0.83
847_K	850_L	1.228	0.83
306_Q	312_S	1.227	0.83
123_I	138_N	1.225	0.83
828_S	833_S	1.220	0.83
927_V	931_E	1.216	0.83
758_A	834_I	1.216	0.83
852_I	882_V	1.209	0.82
304_E	312_S	1.209	0.82
117_E	140_L	1.207	0.82
577_K	628_A	1.207	0.82
372_V	620_Q	1.203	0.82
218_E	463_Y	1.201	0.82
497_V	505_E	1.198	0.82
876_L	879_I	1.195	0.82
194_R	228_D	1.185	0.81
188_L	495_K	1.185	0.81
497_V	507_V	1.184	0.81
137_S	141_E	1.182	0.81
220_L	394_A	1.179	0.81
759_A	807_Q	1.178	0.81
598_S	629_Q	1.172	0.80
190_A	228_D	1.171	0.80
707_A	731_P	1.170	0.80
573_N	636_D	1.163	0.80
791_N	795_V	1.159	0.80
837_S	841_N	1.159	0.80
234_S	356_L	1.155	0.79
199_E	490_Q	1.152	0.79
359_L	389_A	1.149	0.79
827_L	899_L	1.148	0.79
107_L	113_Y	1.145	0.79
643_F	648_H	1.144	0.79
683_L	719_V	1.144	0.79
239_T	356_L	1.142	0.79
489_K	507_V	1.141	0.78
383_G	618_T	1.139	0.78
829_S	891_A	1.137	0.78
314_R	714_Q	1.137	0.78
31_T	49_G	1.135	0.78
263_Y	514_V	1.134	0.78
201_F	256_A	1.131	0.78
595_V	801_L	1.127	0.78
609_L	656_F	1.127	0.78
666_G	696_A	1.124	0.77
381_L	662_P	1.123	0.77
329_P	371_I	1.120	0.77
746_A	859_Y	1.118	0.77
824_R	850_L	1.116	0.77
191_V	433_E	1.113	0.77
237_S	444_E	1.111	0.77
617_L	622_S	1.110	0.76
110_L	114_G	1.109	0.76
383_G	659_H	1.109	0.76
935_I	938_D	1.109	0.76
247_A	326_F	1.108	0.76
727_E	785_P	1.107	0.76
551_T	767_R	1.104	0.76
726_Y	886_P	1.103	0.76
234_S	447_K	1.102	0.76
801_L	804_S	1.100	0.76
124_P	142_A	1.100	0.76
192_L	502_V	1.100	0.76
462_R	487_T	1.095	0.75
425_V	441_F	1.094	0.75
83_E	87_T	1.088	0.75
540_E	777_I	1.087	0.75
227_L	457_L	1.087	0.75
623_E	633_V	1.083	0.75
703_Q	732_E	1.082	0.75
358_I	439_V	1.074	0.74
820_E	875_N	1.072	0.74
710_A	747_E	1.070	0.74
183_N	191_V	1.069	0.74
502_V	507_V	1.067	0.74
726_Y	734_S	1.066	0.74
560_K	564_E	1.065	0.73
96_N	424_I	1.063	0.73
887_Q	911_Y	1.063	0.73
242_V	358_I	1.063	0.73
584_R	587_K	1.061	0.73
198_V	217_I	1.060	0.73
589_F	595_V	1.060	0.73
270_F	296_K	1.057	0.73
922_E	927_V	1.057	0.73
231_I	242_V	1.056	0.73
555_F	802_S	1.053	0.73
566_I	586_A	1.053	0.73
810_Y	853_A	1.051	0.72
335_T	339_Q	1.044	0.72
344_Q	351_D	1.043	0.72
721_L	761_Y	1.042	0.72
497_V	504_E	1.041	0.72
384_Y	671_F	1.040	0.72
827_L	879_I	1.039	0.72
629_Q	784_T	1.038	0.71
564_E	567_N	1.033	0.71
812_Q	837_S	1.033	0.71
416_L	620_Q	1.032	0.71
245_G	327_I	1.030	0.71
224_V	258_V	1.026	0.71
839_H	937_S	1.026	0.71
480_D	484_K	1.023	0.70
486_P	491_I	1.023	0.70
120_I	140_L	1.023	0.70
328_N	670_G	1.019	0.70
887_Q	913_G	1.018	0.70
812_Q	817_H	1.018	0.70
917_R	920_P	1.015	0.70
170_L	438_A	1.014	0.70
439_V	455_I	1.013	0.70
487_T	490_Q	1.012	0.70
340_E	675_Y	1.010	0.69
549_V	770_K	1.008	0.69
800_E	829_S	1.007	0.69
256_A	263_Y	1.007	0.69
851_H	873_L	1.004	0.69
717_G	777_I	1.004	0.69
879_I	899_L	1.003	0.69
185_A	506_V	1.002	0.69
808_P	857_Q	1.002	0.69
81_L	143_I	1.000	0.69
747_E	894_Y	1.000	0.69
598_S	810_Y	1.000	0.69
823_T	847_K	0.999	0.69
212_Q	216_S	0.998	0.68
340_E	657_A	0.997	0.68
164_F	168_E	0.997	0.68
761_Y	782_I	0.997	0.68
559_R	590_D	0.993	0.68
540_E	717_G	0.993	0.68
667_S	696_A	0.991	0.68
259_L	315_I	0.990	0.68
444_E	448_T	0.990	0.68
882_V	912_I	0.990	0.68
540_E	680_P	0.987	0.68
369_E	664_S	0.986	0.67
39_P	43_E	0.985	0.67
858_L	895_I	0.984	0.67
493_A	507_V	0.984	0.67
558_L	603_L	0.984	0.67
727_E	932_Q	0.984	0.67
620_Q	718_L	0.983	0.67
690_Y	729_Q	0.980	0.67
819_Y	874_P	0.977	0.67
30_Y	42_K	0.976	0.67
649_L	653_S	0.975	0.67
377_N	419_G	0.973	0.66
29_Q	38_D	0.971	0.66
741_F	745_A	0.971	0.66
926_T	929_K	0.971	0.66
811_E	872_K	0.968	0.66
831_K	835_D	0.966	0.66
373_A	377_N	0.966	0.66
600_A	761_Y	0.965	0.66
880_V	910_Q	0.964	0.66
629_Q	761_Y	0.963	0.66
229_D	436_L	0.963	0.66
236_K	309_E	0.962	0.66
685_L	784_T	0.962	0.66
726_Y	928_H	0.962	0.66
669_L	705_I	0.961	0.65
139_G	142_A	0.961	0.65
755_L	782_I	0.959	0.65
825_L	879_I	0.957	0.65
572_F	582_L	0.956	0.65
460_Y	487_T	0.956	0.65
727_E	746_A	0.955	0.65
721_L	785_P	0.955	0.65
895_I	899_L	0.955	0.65
677_V	716_S	0.954	0.65
27_Y	31_T	0.952	0.65
170_L	174_I	0.951	0.65
605_F	629_Q	0.948	0.64
445_Y	451_K	0.945	0.64
588_A	591_D	0.944	0.64
827_L	870_F	0.943	0.64
820_E	874_P	0.943	0.64
497_V	502_V	0.943	0.64
243_N	335_T	0.940	0.64
314_R	540_E	0.940	0.64
211_G	746_A	0.939	0.64
222_A	488_V	0.936	0.63
587_K	590_D	0.935	0.63
410_T	419_G	0.934	0.63
787_S	932_Q	0.932	0.63
342_R	354_K	0.930	0.63
190_A	232_A	0.930	0.63
600_A	794_T	0.929	0.63
443_V	447_K	0.929	0.63
554_D	803_E	0.928	0.63
679_S	682_T	0.928	0.63
757_S	834_I	0.927	0.63
505_E	509_N	0.927	0.63
335_T	355_S	0.926	0.63
192_L	196_T	0.923	0.62
912_I	935_I	0.923	0.62
376_L	454_L	0.921	0.62
685_L	761_Y	0.920	0.62
876_L	907_V	0.919	0.62
867_K	871_A	0.918	0.62
858_L	894_Y	0.917	0.62
550_D	805_R	0.914	0.62
393_I	454_L	0.913	0.61
839_H	936_V	0.913	0.61
726_Y	889_M	0.913	0.61
865_G	868_E	0.912	0.61
392_I	439_V	0.910	0.61
609_L	649_L	0.910	0.61
231_I	313_A	0.910	0.61
523_Q	527_S	0.908	0.61
540_E	776_E	0.906	0.61
558_L	801_L	0.906	0.61
241_S	355_S	0.905	0.61
574_V	582_L	0.905	0.61
861_F	902_I	0.905	0.61
880_V	912_I	0.905	0.61
812_Q	840_F	0.903	0.61
613_T	654_T	0.903	0.61
245_G	331_V	0.901	0.60
39_P	42_K	0.900	0.60
818_D	822_V	0.898	0.60
581_I	628_A	0.897	0.60
557_V	560_K	0.896	0.60
727_E	784_T	0.896	0.60
647_H	656_F	0.896	0.60
623_E	635_H	0.896	0.60
839_H	933_E	0.894	0.60
799_Q	803_E	0.893	0.60
235_V	310_T	0.892	0.60
470_E	577_K	0.891	0.60
556_D	559_R	0.890	0.59
233_Q	440_K	0.888	0.59
694_A	744_L	0.887	0.59
889_M	919_S	0.887	0.59
650_S	654_T	0.885	0.59
554_D	802_S	0.884	0.59
129_C	142_A	0.883	0.59
701_F	706_S	0.882	0.59
610_K	649_L	0.881	0.59
868_E	872_K	0.881	0.59
170_L	453_F	0.880	0.59
26_L	38_D	0.880	0.59
827_L	853_A	0.880	0.59
879_I	909_V	0.879	0.59
77_S	80_R	0.879	0.59
468_M	577_K	0.876	0.58
787_S	791_N	0.873	0.58
809_V	869_L	0.872	0.58
328_N	389_A	0.871	0.58
758_A	791_N	0.871	0.58
264_E	524_K	0.870	0.58
33_D	37_I	0.869	0.58
517_R	521_A	0.869	0.58
554_D	557_V	0.867	0.57
910_Q	938_D	0.867	0.57
608_I	611_D	0.865	0.57
577_K	596_E	0.860	0.57
847_K	940_L	0.860	0.57
359_L	670_G	0.860	0.57
470_E	483_R	0.859	0.57
206_H	212_Q	0.858	0.57
386_V	389_A	0.857	0.57
895_I	898_Y	0.857	0.57
903_A	909_V	0.853	0.56
580_R	584_R	0.852	0.56
835_D	932_Q	0.852	0.56
292_T	747_E	0.849	0.56
565_L	602_S	0.846	0.56
302_N	540_E	0.846	0.56
574_V	634_L	0.845	0.55
424_I	454_L	0.840	0.55
753_A	784_T	0.839	0.55
217_I	257_H	0.838	0.55
344_Q	350_Q	0.837	0.55
305_L	315_I	0.837	0.55
260_G	303_R	0.836	0.55
840_F	852_I	0.835	0.55
149_T	179_L	0.834	0.55
168_E	172_R	0.833	0.54
852_I	939_S	0.832	0.54
669_L	781_V	0.831	0.54
767_R	857_Q	0.831	0.54
332_E	359_L	0.831	0.54
486_P	490_Q	0.831	0.54
43_E	46_D	0.829	0.54
553_I	762_F	0.829	0.54
88_Y	107_L	0.829	0.54
383_G	746_A	0.828	0.54
157_E	418_K	0.828	0.54
741_F	812_Q	0.826	0.54
356_L	443_V	0.826	0.54
143_I	147_R	0.824	0.54
489_K	511_E	0.824	0.54
68_T	71_L	0.822	0.53
94_S	99_R	0.821	0.53
470_E	575_F	0.821	0.53
796_S	800_E	0.821	0.53
618_T	898_Y	0.819	0.53
297_Y	300_G	0.817	0.53
70_D	73_Q	0.816	0.53
373_A	416_L	0.814	0.53
376_L	419_G	0.813	0.53
519_E	523_Q	0.812	0.53
234_S	237_S	0.812	0.53
332_E	389_A	0.811	0.52
904_P	907_V	0.811	0.52
196_T	507_V	0.810	0.52
761_Y	765_L	0.809	0.52
618_T	659_H	0.808	0.52
215_F	297_Y	0.807	0.52
231_I	315_I	0.805	0.52
326_F	699_V	0.802	0.52
666_G	700_Y	0.802	0.52
861_F	866_V	0.800	0.51
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470_E	831_K	0.798	0.51
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747_E	918_S	0.796	0.51
179_L	437_S	0.796	0.51
34_P	42_K	0.796	0.51
332_E	357_A	0.796	0.51
853_A	876_L	0.795	0.51
493_A	497_V	0.795	0.51
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212_Q	332_E	0.793	0.51
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568_W	582_L	0.791	0.51
615_I	825_L	0.789	0.50
110_L	115_L	0.789	0.50
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811_E	819_Y	0.787	0.50
137_S	142_A	0.784	0.50
609_L	655_S	0.784	0.50
757_S	796_S	0.781	0.50
506_V	509_N	0.779	0.50
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215_F	261_K	0.777	0.49
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565_L	589_F	0.775	0.49
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430_D	460_Y	0.774	0.49
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413_A	578_L	0.774	0.49
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204_F	519_E	0.770	0.49
588_A	595_V	0.769	0.49
558_L	802_S	0.769	0.49
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656_F	801_L	0.769	0.49
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595_V	603_L	0.765	0.48
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262_P	522_Y	0.764	0.48
21_G	25_E	0.763	0.48
578_L	634_L	0.763	0.48
229_D	439_V	0.763	0.48
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380_S	385_Q	0.761	0.48
922_E	935_I	0.761	0.48
649_L	652_C	0.761	0.48
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188_L	501_V	0.760	0.48
211_G	859_Y	0.760	0.48
134_K	137_S	0.760	0.48
109_P	112_D	0.759	0.48
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812_Q	940_L	0.757	0.48
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142_A	156_F	0.754	0.47
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170_L	441_F	0.752	0.47
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884_E	891_A	0.752	0.47
183_N	436_L	0.752	0.47
600_A	797_E	0.749	0.47
738_I	784_T	0.748	0.47
887_Q	901_E	0.747	0.47
209_F	328_N	0.747	0.47
477_M	640_G	0.747	0.47
316_T	338_A	0.746	0.47
158_F	171_T	0.744	0.46
618_T	658_V	0.743	0.46
644_V	656_F	0.742	0.46
163_D	708_G	0.742	0.46
784_T	831_K	0.742	0.46
581_I	588_A	0.740	0.46
600_A	756_T	0.740	0.46
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225_P	460_Y	0.739	0.46
228_D	258_V	0.739	0.46
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403_E	623_E	0.738	0.46
562_N	589_F	0.738	0.46
389_A	452_D	0.738	0.46
536_I	540_E	0.737	0.46
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292_T	922_E	0.736	0.46
761_Y	794_T	0.735	0.46
605_F	765_L	0.735	0.46
438_A	455_I	0.734	0.45
76_A	79_V	0.733	0.45
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559_R	563_G	0.731	0.45
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196_T	493_A	0.726	0.45
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329_P	383_G	0.725	0.45
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237_S	447_K	0.722	0.44
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937_S	941_T	0.721	0.44
633_V	642_E	0.720	0.44
44_M	48_L	0.720	0.44
893_G	897_P	0.719	0.44
589_F	798_V	0.719	0.44
552_S	803_E	0.718	0.44
186_E	189_S	0.718	0.44
193_E	510_I	0.717	0.44
150_Y	175_E	0.717	0.44
420_Y	424_I	0.717	0.44
582_L	912_I	0.716	0.44
576_G	579_K	0.716	0.44
85_I	151_K	0.716	0.44
379_S	420_Y	0.713	0.44
788_L	835_D	0.713	0.44
226_V	457_L	0.712	0.44
836_I	939_S	0.711	0.43
578_L	582_L	0.711	0.43
216_S	377_N	0.710	0.43
316_T	717_G	0.710	0.43
140_L	144_Q	0.709	0.43
817_H	848_E	0.707	0.43
394_A	459_G	0.706	0.43
591_D	594_K	0.706	0.43
183_N	188_L	0.706	0.43
610_K	650_S	0.705	0.43
369_E	373_A	0.704	0.43
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91_L	105_S	0.704	0.43
746_A	916_R	0.702	0.43
326_F	696_A	0.701	0.43
556_D	560_K	0.701	0.43
472_S	475_Q	0.701	0.43
932_Q	940_L	0.700	0.42
635_H	824_R	0.700	0.42
413_A	458_I	0.699	0.42
555_F	798_V	0.699	0.42
78_A	341_T	0.698	0.42
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680_P	777_I	0.697	0.42
864_K	867_K	0.697	0.42
824_R	880_V	0.697	0.42
629_Q	794_T	0.696	0.42
199_E	203_Q	0.695	0.42
573_N	579_K	0.695	0.42
183_N	440_K	0.695	0.42
560_K	610_K	0.694	0.42
117_E	121_K	0.694	0.42
211_G	727_E	0.694	0.42
174_I	441_F	0.693	0.42
192_L	510_I	0.693	0.42
245_G	359_L	0.693	0.42
293_G	296_K	0.692	0.42
726_Y	920_P	0.692	0.42
221_D	487_T	0.692	0.42
477_M	481_A	0.692	0.42
798_V	802_S	0.692	0.42
271_Q	660_N	0.692	0.42
292_T	710_A	0.691	0.42
636_D	641_K	0.691	0.42
148_N	152_R	0.690	0.42
501_V	505_E	0.689	0.41
268_S	273_A	0.689	0.41
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617_L	784_T	0.688	0.41
358_I	527_S	0.688	0.41
930_K	934_R	0.688	0.41
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868_E	871_A	0.686	0.41
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868_E	894_Y	0.686	0.41
572_F	636_D	0.685	0.41
338_A	355_S	0.684	0.41
256_A	889_M	0.684	0.41
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414_S	618_T	0.683	0.41
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865_G	869_L	0.682	0.41
390_I	503_T	0.681	0.41
121_K	138_N	0.681	0.41
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244_I	259_L	0.680	0.41
756_T	796_S	0.679	0.41
339_Q	352_E	0.679	0.41
366_F	393_I	0.678	0.41
231_I	390_I	0.678	0.41
382_K	406_E	0.677	0.40
224_V	254_V	0.677	0.40
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246_M	254_V	0.669	0.40
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756_T	794_T	0.666	0.39
550_D	607_S	0.666	0.39
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721_L	920_P	0.665	0.39
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167_R	171_T	0.660	0.39
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299_L	319_N	0.657	0.39
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914_R	931_E	0.655	0.39
866_V	894_Y	0.655	0.39
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893_G	898_Y	0.653	0.38
307_D	311_K	0.652	0.38
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328_N	919_S	0.650	0.38
754_N	760_Q	0.649	0.38
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197_E	514_V	0.648	0.38
520_D	524_K	0.648	0.38
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159_D	410_T	0.644	0.38
261_K	296_K	0.643	0.38
571_S	641_K	0.643	0.38
879_I	907_V	0.642	0.37
672_E	708_G	0.642	0.37
899_L	909_V	0.642	0.37
381_L	384_Y	0.641	0.37
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673_Y	859_Y	0.639	0.37
390_I	455_I	0.639	0.37
217_I	220_L	0.638	0.37
597_W	785_P	0.638	0.37
879_I	903_A	0.638	0.37
190_A	193_E	0.638	0.37
64_K	67_V	0.638	0.37
341_T	679_S	0.638	0.37
241_S	314_R	0.638	0.37
211_G	216_S	0.634	0.37
186_E	486_P	0.634	0.37
622_S	708_G	0.633	0.37
266_I	381_L	0.633	0.37
515_T	931_E	0.633	0.37
211_G	383_G	0.632	0.37
813_S	841_N	0.631	0.36
586_A	590_D	0.630	0.36
567_N	586_A	0.630	0.36
490_Q	560_K	0.629	0.36
174_I	179_L	0.628	0.36
741_F	744_L	0.627	0.36
123_I	141_E	0.626	0.36
825_L	874_P	0.626	0.36
79_V	390_I	0.625	0.36
694_A	729_Q	0.624	0.36
381_L	404_S	0.624	0.36
574_V	579_K	0.624	0.36
95_V	458_I	0.623	0.36
497_V	800_E	0.623	0.36
565_L	634_L	0.623	0.36
132_A	137_S	0.622	0.36
676_N	681_E	0.622	0.36
811_E	851_H	0.621	0.36
568_W	571_S	0.621	0.36
421_E	660_N	0.620	0.36
866_V	900_T	0.619	0.35
757_S	807_Q	0.619	0.35
829_S	849_W	0.619	0.35
242_V	268_S	0.619	0.35
669_L	688_A	0.619	0.35
580_R	768_Q	0.618	0.35
930_K	933_E	0.618	0.35
161_V	170_L	0.618	0.35
429_A	886_P	0.617	0.35
419_G	422_I	0.617	0.35
203_Q	463_Y	0.617	0.35
191_V	823_T	0.616	0.35
420_Y	454_L	0.616	0.35
470_E	787_S	0.615	0.35
318_A	677_V	0.615	0.35
823_T	880_V	0.614	0.35
127_V	158_F	0.614	0.35
28_D	31_T	0.614	0.35
721_L	794_T	0.613	0.35
814_G	840_F	0.613	0.35
185_A	499_E	0.611	0.35
473_T	581_I	0.611	0.35
809_V	853_A	0.611	0.35
24_L	41_L	0.611	0.35
623_E	642_E	0.610	0.35
270_F	300_G	0.610	0.35
35_N	42_K	0.610	0.35
662_P	667_S	0.610	0.35
404_S	407_S	0.610	0.35
358_I	756_T	0.610	0.35
788_L	791_N	0.609	0.35
386_V	582_L	0.609	0.35
96_N	99_R	0.609	0.35
548_D	805_R	0.609	0.35
314_R	539_P	0.609	0.35
607_S	753_A	0.609	0.35
455_I	644_V	0.608	0.35
809_V	825_L	0.608	0.35
470_E	628_A	0.607	0.35
81_L	139_G	0.607	0.35
80_R	83_E	0.606	0.34
609_L	654_T	0.606	0.34
862_P	865_G	0.605	0.34
863_A	901_E	0.605	0.34
96_N	397_M	0.605	0.34
566_I	582_L	0.605	0.34
223_L	227_L	0.604	0.34
751_T	857_Q	0.603	0.34
842_K	845_D	0.603	0.34
207_R	515_T	0.603	0.34
292_T	731_P	0.603	0.34
869_L	879_I	0.602	0.34
75_I	78_A	0.602	0.34
595_V	607_S	0.602	0.34
244_I	684_V	0.602	0.34
557_V	561_L	0.601	0.34
304_E	714_Q	0.600	0.34
755_L	784_T	0.600	0.34
741_F	747_E	0.598	0.34
494_E	497_V	0.598	0.34
581_I	599_L	0.598	0.34
840_F	850_L	0.598	0.34
577_K	727_E	0.597	0.34
209_F	212_Q	0.597	0.34
701_F	750_W	0.597	0.34
787_S	835_D	0.595	0.34
680_P	767_R	0.595	0.34
526_P	644_V	0.595	0.34
383_G	668_V	0.595	0.34
768_Q	778_R	0.594	0.33
694_A	720_M	0.593	0.33
584_R	596_E	0.593	0.33
565_L	582_L	0.593	0.33
366_F	373_A	0.592	0.33
334_S	338_A	0.592	0.33
833_S	854_R	0.592	0.33
935_I	939_S	0.591	0.33
216_S	628_A	0.590	0.33
553_I	798_V	0.589	0.33
600_A	800_E	0.589	0.33
384_Y	662_P	0.589	0.33
108_F	113_Y	0.589	0.33
366_F	372_V	0.588	0.33
390_I	781_V	0.588	0.33
554_D	615_I	0.587	0.33
410_T	416_L	0.587	0.33
746_A	787_S	0.586	0.33
436_L	440_K	0.586	0.33
821_K	910_Q	0.586	0.33
378_L	580_R	0.586	0.33
154_I	230_I	0.586	0.33
815_L	819_Y	0.585	0.33
425_V	606_A	0.585	0.33
352_E	385_Q	0.585	0.33
193_E	513_S	0.585	0.33
199_E	899_L	0.584	0.33
102_E	154_I	0.583	0.33
563_G	654_T	0.583	0.33
781_V	813_S	0.583	0.33
93_A	98_L	0.583	0.33
613_T	682_T	0.582	0.32
774_R	777_I	0.582	0.32
161_V	421_E	0.582	0.32
884_E	940_L	0.582	0.32
180_F	188_L	0.582	0.32
212_Q	269_E	0.582	0.32
208_T	622_S	0.581	0.32
508_Q	511_E	0.581	0.32
558_L	589_F	0.581	0.32
664_S	667_S	0.581	0.32
42_K	76_A	0.580	0.32
672_E	862_P	0.579	0.32
704_F	918_S	0.578	0.32
33_D	938_D	0.578	0.32
383_G	662_P	0.578	0.32
202_E	297_Y	0.577	0.32
421_E	424_I	0.577	0.32
198_V	257_H	0.577	0.32
101_D	488_V	0.576	0.32
721_L	831_K	0.576	0.32
666_G	670_G	0.576	0.32
754_N	783_M	0.576	0.32
727_E	835_D	0.576	0.32
177_G	437_S	0.576	0.32
261_K	270_F	0.576	0.32
189_S	501_V	0.575	0.32
462_R	468_M	0.575	0.32
758_A	797_E	0.574	0.32
338_A	678_H	0.574	0.32
29_Q	32_Q	0.573	0.32
242_V	313_A	0.573	0.32
204_F	561_L	0.573	0.32
44_M	50_A	0.573	0.32
389_A	409_S	0.572	0.32
138_N	185_A	0.572	0.32
78_A	139_G	0.572	0.32
70_D	482_V	0.571	0.32
440_K	444_E	0.571	0.32
366_F	451_K	0.571	0.32
424_I	902_I	0.570	0.32
148_N	315_I	0.570	0.32
206_H	463_Y	0.570	0.32
93_A	570_E	0.570	0.32
808_P	864_K	0.570	0.32
318_A	331_V	0.570	0.32
620_Q	706_S	0.568	0.31
270_F	297_Y	0.568	0.31
215_F	269_E	0.568	0.31
37_I	42_K	0.568	0.31
381_L	402_T	0.568	0.31
622_S	784_T	0.566	0.31
608_I	770_K	0.566	0.31
666_G	704_F	0.565	0.31
801_L	823_T	0.565	0.31
222_A	436_L	0.565	0.31
296_K	300_G	0.564	0.31
828_S	858_L	0.564	0.31
373_A	454_L	0.563	0.31
644_V	647_H	0.563	0.31
202_E	296_K	0.562	0.31
811_E	853_A	0.562	0.31
645_P	656_F	0.562	0.31
430_D	488_V	0.561	0.31
812_Q	841_N	0.560	0.31
115_L	218_E	0.560	0.31
826_V	853_A	0.560	0.31
826_V	832_V	0.560	0.31
329_P	375_T	0.559	0.31
112_D	736_G	0.559	0.31
531_H	534_C	0.559	0.31
823_T	872_K	0.558	0.31
823_T	835_D	0.558	0.31
120_I	143_I	0.557	0.31
199_E	489_K	0.557	0.31
158_F	587_K	0.557	0.31
169_W	676_N	0.557	0.31
244_I	315_I	0.556	0.30
622_S	659_H	0.556	0.30
113_Y	810_Y	0.556	0.30
727_E	859_Y	0.556	0.30
521_A	524_K	0.556	0.30
435_C	455_I	0.556	0.30
269_E	296_K	0.556	0.30
403_E	792_P	0.556	0.30
568_W	572_F	0.555	0.30
406_E	438_A	0.555	0.30
558_L	595_V	0.555	0.30
188_L	492_F	0.555	0.30
198_V	221_D	0.555	0.30
556_D	820_E	0.555	0.30
196_T	483_R	0.554	0.30
315_I	703_Q	0.554	0.30
200_G	515_T	0.554	0.30
754_N	761_Y	0.553	0.30
865_G	873_L	0.553	0.30
690_Y	794_T	0.553	0.30
561_L	649_L	0.552	0.30
812_Q	852_I	0.552	0.30
70_D	705_I	0.551	0.30
189_S	193_E	0.551	0.30
157_E	205_L	0.550	0.30
123_I	436_L	0.550	0.30
758_A	833_S	0.550	0.30
115_L	124_P	0.550	0.30
257_H	300_G	0.549	0.30
540_E	778_R	0.549	0.30
565_L	649_L	0.549	0.30
581_I	602_S	0.549	0.30
87_T	159_D	0.549	0.30
754_N	785_P	0.548	0.30
822_V	875_N	0.548	0.30
813_S	840_F	0.547	0.30
234_S	313_A	0.547	0.30
415_D	418_K	0.546	0.30
643_F	653_S	0.546	0.30
156_F	425_V	0.546	0.30
244_I	407_S	0.546	0.30
226_V	640_G	0.546	0.30
167_R	424_I	0.546	0.30
819_Y	822_V	0.546	0.30
402_T	406_E	0.545	0.30
77_S	115_L	0.545	0.30
74_K	216_S	0.545	0.30
886_P	889_M	0.545	0.30
35_N	39_P	0.544	0.30
559_R	798_V	0.544	0.30
22_Y	29_Q	0.544	0.30
835_D	935_I	0.544	0.30
25_E	29_Q	0.544	0.30
758_A	796_S	0.544	0.30
393_I	422_I	0.543	0.29
254_V	360_I	0.543	0.29
928_H	935_I	0.543	0.29
402_T	428_N	0.543	0.29
755_L	889_M	0.543	0.29
564_E	648_H	0.542	0.29
579_K	898_Y	0.542	0.29
67_V	71_L	0.542	0.29
158_F	164_F	0.542	0.29
185_A	512_K	0.541	0.29
184_S	390_I	0.541	0.29
393_I	545_G	0.541	0.29
238_G	824_R	0.540	0.29
215_F	296_K	0.540	0.29
193_E	407_S	0.540	0.29
118_E	667_S	0.540	0.29
705_I	718_L	0.540	0.29
867_K	899_L	0.540	0.29
394_A	751_T	0.540	0.29
152_R	861_F	0.539	0.29
799_Q	866_V	0.539	0.29
618_T	622_S	0.538	0.29
313_A	497_V	0.538	0.29
229_D	441_F	0.538	0.29
911_Y	915_R	0.538	0.29
203_Q	559_R	0.537	0.29
741_F	814_G	0.537	0.29
394_A	429_A	0.536	0.29
74_K	122_A	0.536	0.29
75_I	124_P	0.536	0.29
560_K	651_D	0.536	0.29
574_V	578_L	0.536	0.29
677_V	708_G	0.535	0.29
367_P	373_A	0.535	0.29
126_S	228_D	0.535	0.29
609_L	653_S	0.535	0.29
20_L	152_R	0.535	0.29
559_R	592_D	0.535	0.29
827_L	858_L	0.534	0.29
647_H	653_S	0.534	0.29
18_P	23_A	0.533	0.29
354_K	820_E	0.533	0.29
95_V	100_K	0.533	0.29
239_T	386_V	0.533	0.29
559_R	606_A	0.533	0.29
618_T	667_S	0.533	0.29
495_K	498_K	0.533	0.29
371_I	700_Y	0.532	0.29
822_V	825_L	0.532	0.29
332_E	684_V	0.532	0.29
96_N	454_L	0.532	0.29
371_I	669_L	0.532	0.29
376_L	441_F	0.531	0.29
157_E	747_E	0.531	0.29
546_F	549_V	0.531	0.29
485_H	488_V	0.531	0.29
670_G	889_M	0.531	0.29
819_Y	869_L	0.530	0.29
142_A	146_L	0.530	0.29
116_T	122_A	0.530	0.29
95_V	98_L	0.530	0.29
86_R	673_Y	0.530	0.29
756_T	778_R	0.529	0.28
155_S	412_Y	0.529	0.28
578_L	754_N	0.529	0.28
828_S	881_W	0.528	0.28
410_T	913_G	0.528	0.28
823_T	874_P	0.528	0.28
170_L	377_N	0.528	0.28
96_N	472_S	0.528	0.28
470_E	791_N	0.528	0.28
751_T	776_E	0.528	0.28
672_E	829_S	0.528	0.28
609_L	646_L	0.527	0.28
402_T	622_S	0.527	0.28
66_R	69_A	0.526	0.28
47_E	51_P	0.526	0.28
707_A	828_S	0.526	0.28
457_L	528_K	0.526	0.28
71_L	122_A	0.526	0.28
759_A	762_F	0.525	0.28
87_T	162_H	0.525	0.28
608_I	613_T	0.525	0.28
878_E	903_A	0.524	0.28
577_K	581_I	0.524	0.28
414_S	420_Y	0.524	0.28
155_S	700_Y	0.524	0.28
377_N	409_S	0.523	0.28
235_V	309_E	0.523	0.28
565_L	572_F	0.523	0.28
128_I	139_G	0.523	0.28
232_A	309_E	0.523	0.28
30_Y	639_T	0.522	0.28
450_N	919_S	0.522	0.28
502_V	510_I	0.522	0.28
800_E	838_D	0.522	0.28
572_F	642_E	0.522	0.28
65_G	69_A	0.522	0.28
96_N	108_F	0.521	0.28
756_T	760_Q	0.521	0.28
335_T	344_Q	0.521	0.28
206_H	210_V	0.520	0.28
381_L	473_T	0.520	0.28
883_Q	888_N	0.519	0.28
554_D	611_D	0.519	0.28
342_R	635_H	0.519	0.28
28_D	39_P	0.519	0.28
189_S	598_S	0.518	0.28
239_T	855_I	0.518	0.28
817_H	822_V	0.518	0.28
339_Q	344_Q	0.518	0.28
225_P	231_I	0.518	0.28
67_V	424_I	0.518	0.28
799_Q	802_S	0.517	0.28
870_F	879_I	0.517	0.28
832_V	936_V	0.517	0.28
195_L	782_I	0.517	0.28
477_M	480_D	0.517	0.28
360_I	445_Y	0.517	0.28
603_L	756_T	0.516	0.27
864_K	868_E	0.516	0.27
635_H	644_V	0.516	0.27
211_G	468_M	0.515	0.27
187_K	232_A	0.515	0.27
358_I	491_I	0.515	0.27
81_L	85_I	0.515	0.27
316_T	596_E	0.515	0.27
228_D	232_A	0.514	0.27
451_K	741_F	0.514	0.27
222_A	607_S	0.514	0.27
694_A	736_G	0.514	0.27
190_A	308_A	0.514	0.27
340_E	655_S	0.514	0.27
384_Y	452_D	0.514	0.27
329_P	700_Y	0.514	0.27
343_T	822_V	0.513	0.27
913_G	938_D	0.513	0.27
738_I	752_V	0.513	0.27
838_D	853_A	0.513	0.27
493_A	511_E	0.513	0.27
512_K	629_Q	0.512	0.27
221_D	226_V	0.512	0.27
257_H	263_Y	0.511	0.27
326_F	393_I	0.511	0.27
814_G	837_S	0.511	0.27
653_S	917_R	0.510	0.27
29_Q	37_I	0.510	0.27
393_I	805_R	0.510	0.27
29_Q	634_L	0.509	0.27
681_E	807_Q	0.509	0.27
628_A	794_T	0.509	0.27
183_N	437_S	0.509	0.27
93_A	96_N	0.509	0.27
366_F	416_L	0.508	0.27
552_S	607_S	0.508	0.27
615_I	656_F	0.507	0.27
113_Y	741_F	0.507	0.27
664_S	696_A	0.507	0.27
213_K	690_Y	0.506	0.27
227_L	358_I	0.506	0.27
83_E	128_I	0.506	0.27
36_S	554_D	0.505	0.27
699_V	738_I	0.505	0.27
116_T	880_V	0.505	0.27
190_A	826_V	0.505	0.27
480_D	483_R	0.505	0.27
392_I	736_G	0.505	0.27
119_E	198_V	0.505	0.27
562_N	758_A	0.504	0.27
339_Q	404_S	0.504	0.27
46_D	50_A	0.504	0.27
196_T	200_G	0.504	0.27
187_K	526_P	0.504	0.27
26_L	234_S	0.503	0.27
622_S	667_S	0.503	0.27
810_Y	872_K	0.503	0.27
239_T	868_E	0.502	0.26
881_W	884_E	0.502	0.26
51_P	64_K	0.502	0.26
623_E	659_H	0.502	0.26
505_E	508_Q	0.502	0.26
811_E	822_V	0.502	0.26
783_M	829_S	0.502	0.26
305_L	309_E	0.501	0.26
31_T	448_T	0.501	0.26
81_L	726_Y	0.501	0.26
59_S	144_Q	0.501	0.26
227_L	875_N	0.500	0.26
884_E	936_V	0.500	0.26
83_E	164_F	0.500	0.26
201_F	515_T	0.500	0.26
326_F	371_I	0.500	0.26

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2jgdA	2	0.8644	100	0.428	Contact Map
2xt6A	2	0.9333	100	0.438	Contact Map
2yicA	2	0.8496	100	0.444	Contact Map
1itzA	2	0.6684	100	0.853	Contact Map
3komA	2	0.6356	100	0.857	Contact Map
3l84A	2	0.625	100	0.858	Contact Map
4c7vA	2	0.6557	100	0.859	Contact Map
3uk1A	2	0.6398	100	0.86	Contact Map
3rimA	2	0.6716	100	0.863	Contact Map
2r8oA	2	0.6494	100	0.864	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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