SYE - BACSU - GREMLIN Contacts

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SYE - Glutamate--tRNA ligase

UniProt:	P22250	Sequences: MGNEVRVRYAPSPTGHLHIGNARTALFNYLFARNQGGKFIIRVEDTDKKRNIEGGEQSQLNYLKWLGIDWDESVDVGGEYGPYRQSERNDIYKVYYEELLEKGLAYKCYCTEEELEKEREEQIARGEMPRYSGKHRDLTQEEQEKFIAEGRKPSIRFRVPEGKVIAFNDIVKGEISFESDGIGDFVIVKKDGTPTYNFAVAIDDYLMKMTHVLRGEDHISNTPKQIMIYQAFGWDIPQFGHMTLIVNESRKKLSKRDESIIQFIEQYKELGYLPEALFNFIGLLGWSPVGEEELFTKEQFIEIFDVNRLSKSPALFDMHKLKWVNNQYVKKLDLDQVVELTLPHLQKAGKVGTELSAEEQEWVRKLISLYHEQLSYGAEIVELTDLFFTDEIEYNQEAKAVLEEEQVPEVLSTFAAKLEELEEFTPDNIKASIKAVQKETGHKGKKLFMPIRVAVTGQTHGPELPQSIELIGKETAIQRLKNI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	483 (411)
Sequences:	6363 (3566)
Seq/√Len:	175.9

ECOLI - SYE GLUQ SYQ
BACSU - SYE
SULSO - SYE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
98_E	102_K	4.756	1.00
97_E	101_E	4.557	1.00
168_N	174_E	4.316	1.00
53_E	57_Q	4.044	1.00
4_E	38_K	3.874	1.00
110_C	135_H	3.107	1.00
334_L	371_H	2.963	1.00
146_F	151_R	2.800	1.00
57_Q	61_N	2.697	1.00
140_Q	144_E	2.688	1.00
131_Y	135_H	2.622	1.00
144_E	148_A	2.540	1.00
205_Y	234_W	2.512	1.00
229_Y	239_F	2.478	1.00
335_D	364_R	2.375	1.00
121_E	125_R	2.358	1.00
111_T	114_E	2.343	1.00
425_T	428_N	2.237	1.00
96_Y	155_I	2.235	1.00
137_D	141_E	2.211	1.00
117_K	121_E	2.205	1.00
148_A	151_R	2.201	1.00
90_D	94_V	2.195	1.00
97_E	140_Q	2.171	1.00
64_K	69_D	2.151	1.00
56_E	84_R	2.148	1.00
230_Q	236_I	2.147	1.00
141_E	146_F	2.125	1.00
95_Y	206_L	2.122	1.00
109_Y	153_P	2.086	1.00
172_K	216_E	2.081	1.00
91_I	206_L	2.077	1.00
165_I	179_S	2.073	1.00
166_A	176_S	2.067	1.00
90_D	189_K	2.066	1.00
166_A	174_E	2.059	1.00
272_Y	322_K	2.057	1.00
104_L	231_A	2.051	1.00
120_E	123_I	2.031	1.00
170_I	238_Q	2.014	1.00
298_E	302_E	2.010	1.00
31_F	35_Q	1.976	1.00
110_C	118_E	1.959	1.00
292_E	299_Q	1.934	1.00
333_D	336_Q	1.909	1.00
164_V	176_S	1.906	1.00
84_R	87_E	1.898	1.00
145_K	149_E	1.889	1.00
6_R	209_M	1.888	1.00
226_I	236_I	1.883	1.00
326_N	330_K	1.882	1.00
175_I	219_I	1.876	1.00
64_K	70_W	1.873	1.00
96_Y	188_V	1.860	1.00
164_V	178_E	1.844	1.00
94_V	98_E	1.843	1.00
406_Q	409_E	1.819	1.00
92_Y	203_D	1.782	1.00
40_I	209_M	1.775	1.00
9_Y	21_N	1.775	1.00
143_Q	147_I	1.770	1.00
17_L	21_N	1.746	1.00
332_L	336_Q	1.743	1.00
168_N	238_Q	1.742	1.00
139_T	142_E	1.729	1.00
91_I	95_Y	1.721	1.00
415_A	419_E	1.710	1.00
6_R	38_K	1.709	1.00
89_N	193_T	1.687	1.00
41_I	60_L	1.678	1.00
118_E	132_S	1.664	1.00
109_Y	152_K	1.660	1.00
107_K	153_P	1.657	1.00
163_K	230_Q	1.647	1.00
273_L	304_F	1.631	1.00
296_T	299_Q	1.618	1.00
100_L	107_K	1.613	1.00
73_S	83_Y	1.612	1.00
424_F	429_I	1.599	1.00
133_G	136_R	1.586	1.00
109_Y	147_I	1.572	1.00
395_N	398_A	1.570	1.00
157_F	231_A	1.561	1.00
70_W	73_S	1.544	1.00
98_E	101_E	1.528	1.00
211_H	238_Q	1.521	1.00
250_R	315_L	1.517	1.00
91_I	94_V	1.515	1.00
114_E	118_E	1.495	1.00
142_E	145_K	1.486	1.00
179_S	188_V	1.482	1.00
99_L	104_L	1.474	1.00
95_Y	232_F	1.473	1.00
116_E	120_E	1.469	1.00
61_N	265_E	1.466	1.00
416_A	419_E	1.464	1.00
6_R	40_I	1.461	1.00
157_F	227_M	1.452	1.00
108_C	135_H	1.441	1.00
159_V	227_M	1.436	1.00
197_N	225_Q	1.434	1.00
61_N	64_K	1.432	1.00
240_G	306_V	1.409	1.00
413_T	417_K	1.402	1.00
385_D	389_T	1.402	1.00
24_T	215_G	1.400	1.00
399_K	403_E	1.395	1.00
22_A	66_L	1.395	1.00
247_N	257_D	1.393	1.00
275_E	336_Q	1.391	1.00
38_K	71_D	1.391	1.00
413_T	416_A	1.391	1.00
279_N	283_L	1.374	1.00
107_K	147_I	1.367	1.00
140_Q	143_Q	1.366	1.00
65_W	268_K	1.359	1.00
6_R	208_K	1.354	1.00
336_Q	340_L	1.339	1.00
327_Q	331_K	1.335	1.00
234_W	237_P	1.332	1.00
122_Q	127_E	1.328	1.00
52_I	55_G	1.328	1.00
149_E	177_F	1.324	1.00
371_H	374_L	1.321	1.00
375_S	379_E	1.304	1.00
7_V	28_N	1.303	1.00
141_E	147_I	1.303	1.00
107_K	155_I	1.301	1.00
72_E	83_Y	1.297	1.00
95_Y	202_I	1.297	1.00
93_K	97_E	1.290	1.00
328_Y	346_Q	1.284	1.00
96_Y	100_L	1.282	1.00
292_E	303_I	1.271	1.00
319_H	322_K	1.269	1.00
404_E	407_V	1.264	1.00
304_F	308_R	1.259	1.00
26_L	68_I	1.258	1.00
282_G	300_F	1.255	1.00
266_Q	269_E	1.253	1.00
327_Q	330_K	1.251	1.00
100_L	155_I	1.244	1.00
148_A	177_F	1.243	1.00
114_E	117_K	1.242	1.00
205_Y	235_D	1.241	1.00
102_K	233_G	1.226	1.00
40_I	73_S	1.214	1.00
213_L	240_G	1.212	1.00
201_A	228_I	1.209	1.00
60_L	64_K	1.208	1.00
138_L	147_I	1.201	1.00
105_A	155_I	1.194	1.00
112_E	116_E	1.189	1.00
170_I	306_V	1.179	1.00
197_N	221_N	1.169	1.00
114_E	132_S	1.169	1.00
98_E	233_G	1.164	1.00
54_G	57_Q	1.162	1.00
278_F	297_K	1.159	1.00
114_E	134_K	1.158	1.00
356_S	359_E	1.157	1.00
226_I	230_Q	1.155	1.00
135_H	138_L	1.149	1.00
342_L	360_Q	1.145	1.00
294_L	324_V	1.136	1.00
85_Q	199_A	1.136	1.00
29_Y	33_R	1.134	1.00
423_E	428_N	1.126	1.00
146_F	149_E	1.125	1.00
31_F	211_H	1.124	1.00
167_F	219_I	1.120	1.00
100_L	139_T	1.120	1.00
172_K	228_I	1.118	1.00
110_C	131_Y	1.116	1.00
218_H	221_N	1.113	1.00
57_Q	60_L	1.107	1.00
338_V	364_R	1.102	1.00
334_L	337_V	1.100	1.00
95_Y	234_W	1.100	1.00
339_E	360_Q	1.098	1.00
107_K	143_Q	1.093	1.00
114_E	135_H	1.093	1.00
366_L	387_F	1.089	1.00
133_G	158_R	1.086	1.00
5_V	31_F	1.084	1.00
122_Q	126_G	1.084	1.00
29_Y	39_F	1.078	1.00
117_K	120_E	1.077	1.00
266_Q	270_L	1.076	1.00
38_K	72_E	1.076	1.00
157_F	228_I	1.073	1.00
368_S	371_H	1.072	1.00
100_L	105_A	1.066	1.00
249_S	257_D	1.066	1.00
218_H	225_Q	1.066	1.00
411_L	414_F	1.064	1.00
362_W	366_L	1.060	1.00
105_A	187_I	1.056	1.00
44_E	200_V	1.054	1.00
24_T	28_N	1.053	1.00
120_E	124_A	1.051	1.00
60_L	70_W	1.035	0.99
370_Y	380_I	1.035	0.99
101_E	104_L	1.025	0.99
39_F	68_I	1.023	0.99
85_Q	203_D	1.020	0.99
137_D	146_F	1.016	0.99
329_V	373_Q	1.012	0.99
335_D	339_E	1.009	0.99
123_I	126_G	1.007	0.99
88_R	92_Y	1.005	0.99
132_S	135_H	1.003	0.99
297_K	301_I	0.999	0.99
90_D	93_K	0.998	0.99
399_K	404_E	0.998	0.99
336_Q	339_E	0.994	0.99
92_Y	199_A	0.987	0.99
197_N	218_H	0.986	0.99
95_Y	98_E	0.984	0.99
142_E	146_F	0.982	0.99
405_E	408_P	0.980	0.99
48_K	193_T	0.977	0.99
417_K	420_E	0.975	0.99
144_E	147_I	0.972	0.99
334_L	368_S	0.970	0.99
61_N	268_K	0.970	0.99
131_Y	134_K	0.970	0.99
342_L	346_Q	0.966	0.99
48_K	86_S	0.966	0.99
143_Q	192_G	0.965	0.99
322_K	375_S	0.962	0.99
427_D	431_A	0.960	0.99
31_F	213_L	0.960	0.99
53_E	56_E	0.957	0.99
299_Q	303_I	0.953	0.99
56_E	184_D	0.948	0.99
299_Q	302_E	0.948	0.99
16_H	58_S	0.947	0.99
16_H	54_G	0.945	0.99
136_R	158_R	0.943	0.99
138_L	143_Q	0.937	0.99
102_K	231_A	0.936	0.99
292_E	295_F	0.935	0.99
269_E	347_K	0.934	0.99
306_V	309_L	0.934	0.99
409_E	412_S	0.931	0.99
412_S	416_A	0.931	0.99
5_V	211_H	0.931	0.99
94_V	101_E	0.931	0.99
403_E	406_Q	0.926	0.99
108_C	115_L	0.924	0.99
86_S	193_T	0.923	0.99
110_C	134_K	0.923	0.99
163_K	179_S	0.920	0.99
93_K	188_V	0.918	0.99
101_E	140_Q	0.917	0.99
96_Y	105_A	0.916	0.99
404_E	408_P	0.914	0.99
4_E	208_K	0.914	0.99
6_R	72_E	0.913	0.99
94_V	97_E	0.913	0.99
24_T	213_L	0.911	0.99
40_I	83_Y	0.911	0.99
369_L	387_F	0.909	0.99
408_P	412_S	0.908	0.99
145_K	148_A	0.904	0.99
416_A	420_E	0.903	0.99
34_N	305_D	0.896	0.98
273_L	276_A	0.895	0.98
379_E	382_E	0.895	0.98
89_N	93_K	0.894	0.98
400_A	404_E	0.889	0.98
121_E	124_A	0.889	0.98
361_E	365_K	0.887	0.98
6_R	73_S	0.883	0.98
332_L	340_L	0.882	0.98
394_Y	398_A	0.881	0.98
88_R	91_I	0.880	0.98
407_V	411_L	0.880	0.98
306_V	333_D	0.879	0.98
362_W	365_K	0.875	0.98
166_A	221_N	0.871	0.98
405_E	409_E	0.869	0.98
62_Y	265_E	0.869	0.98
340_L	343_P	0.866	0.98
338_V	342_L	0.865	0.98
295_F	300_F	0.865	0.98
122_Q	125_R	0.865	0.98
9_Y	17_L	0.863	0.98
348_A	381_V	0.862	0.98
229_Y	232_F	0.862	0.98
370_Y	384_T	0.862	0.98
118_E	127_E	0.861	0.98
109_Y	151_R	0.853	0.98
403_E	407_V	0.853	0.98
143_Q	146_F	0.847	0.98
428_N	431_A	0.845	0.98
376_Y	379_E	0.843	0.98
167_F	226_I	0.843	0.98
341_T	380_I	0.841	0.98
365_K	368_S	0.836	0.98
328_Y	331_K	0.835	0.98
366_L	384_T	0.825	0.97
275_E	304_F	0.820	0.97
147_I	151_R	0.820	0.97
33_R	69_D	0.817	0.97
318_M	322_K	0.815	0.97
348_A	382_E	0.805	0.97
426_P	430_K	0.805	0.97
399_K	402_L	0.805	0.97
427_D	430_K	0.803	0.97
33_R	71_D	0.803	0.97
157_F	187_I	0.798	0.97
24_T	27_F	0.796	0.97
113_E	116_E	0.794	0.97
141_E	144_E	0.791	0.97
322_K	376_Y	0.789	0.97
329_V	332_L	0.781	0.96
320_K	347_K	0.780	0.96
137_D	147_I	0.779	0.96
98_E	104_L	0.779	0.96
383_L	386_L	0.778	0.96
91_I	98_E	0.776	0.96
294_L	328_Y	0.773	0.96
272_Y	277_L	0.772	0.96
202_I	232_F	0.771	0.96
230_Q	233_G	0.769	0.96
278_F	300_F	0.768	0.96
90_D	143_Q	0.767	0.96
360_Q	364_R	0.765	0.96
393_E	396_Q	0.764	0.96
407_V	410_V	0.763	0.96
172_K	217_D	0.762	0.96
32_A	37_G	0.761	0.96
23_R	242_M	0.761	0.96
21_N	217_D	0.758	0.96
93_K	140_Q	0.758	0.96
400_A	403_E	0.757	0.96
177_F	191_D	0.756	0.96
334_L	338_V	0.754	0.96
257_D	260_I	0.753	0.96
314_A	378_A	0.753	0.96
123_I	129_P	0.753	0.96
267_Y	277_L	0.751	0.96
379_E	383_L	0.750	0.96
97_E	100_L	0.745	0.95
63_L	68_I	0.744	0.95
110_C	115_L	0.740	0.95
272_Y	321_L	0.737	0.95
34_N	301_I	0.736	0.95
165_I	227_M	0.736	0.95
324_V	328_Y	0.731	0.95
40_I	72_E	0.729	0.95
138_L	142_E	0.728	0.95
106_Y	184_D	0.728	0.95
155_I	188_V	0.727	0.95
338_V	367_I	0.725	0.95
9_Y	59_Q	0.725	0.95
147_I	150_G	0.725	0.95
220_S	223_P	0.722	0.94
109_Y	143_Q	0.721	0.94
109_Y	131_Y	0.720	0.94
5_V	35_Q	0.719	0.94
275_E	308_R	0.716	0.94
273_L	325_N	0.713	0.94
343_P	374_L	0.712	0.94
24_T	253_L	0.712	0.94
248_E	319_H	0.707	0.94
221_N	225_Q	0.707	0.94
87_E	185_F	0.705	0.94
118_E	122_Q	0.704	0.94
398_A	401_V	0.704	0.94
118_E	134_K	0.704	0.94
7_V	31_F	0.699	0.93
275_E	340_L	0.699	0.93
414_F	418_L	0.697	0.93
391_E	394_Y	0.693	0.93
412_S	415_A	0.693	0.93
410_V	413_T	0.693	0.93
96_Y	198_F	0.692	0.93
394_Y	397_E	0.690	0.93
298_E	301_I	0.688	0.93
418_L	424_F	0.687	0.93
48_K	51_N	0.686	0.93
292_E	296_T	0.685	0.93
305_D	308_R	0.684	0.93
322_K	347_K	0.682	0.93
201_A	229_Y	0.681	0.93
109_Y	130_R	0.681	0.93
58_S	265_E	0.681	0.93
245_I	293_E	0.681	0.93
185_F	224_K	0.681	0.93
229_Y	234_W	0.680	0.93
260_I	270_L	0.679	0.92
345_L	371_H	0.679	0.92
122_Q	129_P	0.678	0.92
398_A	402_L	0.677	0.92
370_Y	383_L	0.674	0.92
115_L	131_Y	0.672	0.92
397_E	400_A	0.672	0.92
171_V	240_G	0.672	0.92
110_C	114_E	0.671	0.92
130_R	133_G	0.669	0.92
63_L	215_G	0.669	0.92
157_F	185_F	0.669	0.92
233_G	236_I	0.667	0.92
113_E	117_K	0.666	0.92
283_L	300_F	0.665	0.92
228_I	232_F	0.665	0.92
345_L	374_L	0.664	0.92
251_K	257_D	0.663	0.92
422_E	425_T	0.663	0.92
170_I	240_G	0.663	0.92
49_K	52_I	0.663	0.92
321_L	348_A	0.662	0.92
92_Y	202_I	0.662	0.92
167_F	223_P	0.661	0.91
259_S	263_F	0.660	0.91
17_L	24_T	0.659	0.91
28_N	31_F	0.656	0.91
216_E	244_L	0.656	0.91
344_H	348_A	0.655	0.91
51_N	55_G	0.653	0.91
60_L	73_S	0.652	0.91
241_H	249_S	0.651	0.91
183_G	224_K	0.651	0.91
295_F	299_Q	0.650	0.91
411_L	415_A	0.650	0.91
205_Y	208_K	0.649	0.91
165_I	226_I	0.647	0.91
409_E	413_T	0.647	0.91
193_T	217_D	0.645	0.90
323_W	327_Q	0.644	0.90
138_L	146_F	0.643	0.90
202_I	206_L	0.643	0.90
158_R	161_E	0.642	0.90
40_I	74_V	0.641	0.90
172_K	219_I	0.640	0.90
221_N	228_I	0.640	0.90
202_I	234_W	0.640	0.90
275_E	332_L	0.639	0.90
361_E	364_R	0.639	0.90
368_S	372_E	0.638	0.90
284_L	314_A	0.638	0.90
406_Q	410_V	0.635	0.90
122_Q	165_I	0.635	0.90
406_Q	412_S	0.631	0.89
95_Y	198_F	0.631	0.89
25_A	68_I	0.628	0.89
227_M	230_Q	0.626	0.89
202_I	228_I	0.625	0.89
398_A	403_E	0.622	0.89
247_N	259_S	0.621	0.89
247_N	251_K	0.619	0.89
279_N	300_F	0.619	0.89
107_K	152_K	0.618	0.89
137_D	158_R	0.613	0.88
199_A	205_Y	0.612	0.88
59_Q	62_Y	0.612	0.88
177_F	223_P	0.611	0.88
139_T	145_K	0.610	0.88
370_Y	373_Q	0.610	0.88
85_Q	92_Y	0.610	0.88
51_N	54_G	0.607	0.88
69_D	73_S	0.606	0.88
17_L	22_A	0.606	0.88
422_E	428_N	0.604	0.87
362_W	387_F	0.601	0.87
235_D	238_Q	0.601	0.87
267_Y	276_A	0.600	0.87
88_R	203_D	0.600	0.87
229_Y	237_P	0.599	0.87
115_L	154_S	0.598	0.87
93_K	192_G	0.597	0.87
260_I	263_F	0.596	0.87
60_L	74_V	0.596	0.87
247_N	258_E	0.595	0.87
166_A	223_P	0.595	0.87
137_D	140_Q	0.595	0.87
399_K	406_Q	0.594	0.87
359_E	362_W	0.593	0.86
259_S	270_L	0.593	0.86
281_I	284_L	0.591	0.86
270_L	378_A	0.590	0.86
167_F	177_F	0.590	0.86
381_V	384_T	0.589	0.86
396_Q	401_V	0.588	0.86
387_F	392_I	0.588	0.86
26_L	30_L	0.586	0.86
95_Y	201_A	0.585	0.86
86_S	89_N	0.584	0.86
17_L	58_S	0.584	0.86
65_W	274_P	0.583	0.85
166_A	220_S	0.583	0.85
171_V	309_L	0.582	0.85
424_F	428_N	0.582	0.85
374_L	383_L	0.581	0.85
40_I	71_D	0.581	0.85
167_F	222_T	0.580	0.85
205_Y	232_F	0.579	0.85
348_A	385_D	0.577	0.85
199_A	203_D	0.577	0.85
402_L	407_V	0.577	0.85
337_V	367_I	0.576	0.85
121_E	127_E	0.576	0.85
258_E	263_F	0.575	0.85
74_V	83_Y	0.575	0.85
133_G	161_E	0.575	0.85
418_L	429_I	0.574	0.85
326_N	345_L	0.574	0.85
233_G	237_P	0.574	0.85
213_L	306_V	0.573	0.85
361_E	366_L	0.573	0.85
201_A	221_N	0.572	0.84
317_D	409_E	0.570	0.84
143_Q	151_R	0.570	0.84
27_F	215_G	0.569	0.84
48_K	89_N	0.569	0.84
212_V	222_T	0.569	0.84
335_D	338_V	0.568	0.84
270_L	318_M	0.567	0.84
272_Y	276_A	0.566	0.84
316_F	380_I	0.564	0.84
197_N	224_K	0.564	0.84
221_N	224_K	0.564	0.84
414_F	417_K	0.563	0.83
217_D	225_Q	0.560	0.83
391_E	395_N	0.560	0.83
402_L	406_Q	0.559	0.83
265_E	269_E	0.558	0.83
69_D	74_V	0.558	0.83
19_I	277_L	0.558	0.83
404_E	412_S	0.558	0.83
240_G	287_S	0.556	0.83
240_G	309_L	0.556	0.83
63_L	244_L	0.556	0.83
224_K	247_N	0.555	0.83
307_N	333_D	0.555	0.83
110_C	127_E	0.554	0.82
98_E	234_W	0.553	0.82
109_Y	146_F	0.553	0.82
275_E	297_K	0.553	0.82
8_R	11_P	0.552	0.82
9_Y	23_R	0.551	0.82
279_N	293_E	0.549	0.82
44_E	207_M	0.548	0.82
122_Q	132_S	0.547	0.82
407_V	412_S	0.546	0.82
389_T	392_I	0.543	0.81
209_M	212_V	0.543	0.81
51_N	218_H	0.542	0.81
129_P	133_G	0.541	0.81
11_P	15_G	0.541	0.81
30_L	282_G	0.540	0.81
116_E	123_I	0.539	0.81
279_N	304_F	0.538	0.81
358_E	361_E	0.536	0.80
16_H	260_I	0.534	0.80
189_K	225_Q	0.533	0.80
343_P	347_K	0.533	0.80
229_Y	236_I	0.533	0.80
408_P	413_T	0.532	0.80
8_R	13_P	0.531	0.80
89_N	92_Y	0.531	0.80
327_Q	332_L	0.530	0.80
409_E	416_A	0.529	0.80
19_I	316_F	0.529	0.80
355_L	360_Q	0.529	0.80
276_A	328_Y	0.529	0.80
26_L	278_F	0.528	0.79
55_G	58_S	0.528	0.79
260_I	266_Q	0.527	0.79
357_A	360_Q	0.526	0.79
356_S	360_Q	0.525	0.79
122_Q	130_R	0.524	0.79
124_A	129_P	0.523	0.79
129_P	132_S	0.523	0.79
7_V	213_L	0.522	0.79
337_V	341_T	0.521	0.79
39_F	70_W	0.521	0.79
100_L	188_V	0.520	0.78
130_R	134_K	0.519	0.78
115_L	118_E	0.519	0.78
330_K	372_E	0.518	0.78
97_E	107_K	0.517	0.78
222_T	239_F	0.515	0.78
343_P	346_Q	0.515	0.78
115_L	119_R	0.514	0.78
425_T	429_I	0.513	0.77
138_L	141_E	0.513	0.77
72_E	88_R	0.512	0.77
213_L	286_W	0.512	0.77
7_V	39_F	0.512	0.77
53_E	84_R	0.510	0.77
406_Q	411_L	0.510	0.77
198_F	202_I	0.510	0.77
399_K	407_V	0.509	0.77
344_H	378_A	0.509	0.77
295_F	303_I	0.509	0.77
71_D	83_Y	0.509	0.77
300_F	303_I	0.508	0.77
267_Y	318_M	0.508	0.77
414_F	419_E	0.508	0.77
172_K	224_K	0.508	0.77
294_L	327_Q	0.507	0.77
251_K	260_I	0.506	0.77
389_T	393_E	0.505	0.76
170_I	307_N	0.505	0.76
83_Y	207_M	0.505	0.76
189_K	218_H	0.504	0.76
94_V	206_L	0.504	0.76
363_V	366_L	0.503	0.76
287_S	290_G	0.501	0.76
101_E	133_G	0.501	0.76
30_L	300_F	0.501	0.76
21_N	24_T	0.500	0.76

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2ja2A	1	0.9814	100	0.225	Contact Map
4griA	1	0.9834	100	0.236	Contact Map
1j09A	1	0.9607	100	0.242	Contact Map
2cfoA	1	0.9689	100	0.256	Contact Map
3al0C	1	0.9503	100	0.262	Contact Map
3afhA	1	0.9317	100	0.265	Contact Map
2o5rA	1	0.9586	100	0.276	Contact Map
4g6zA	1	0.7867	100	0.283	Contact Map
2hz7A	1	0.8841	100	0.487	Contact Map
4h3sA	1	0.942	100	0.494	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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