SPEA - BACSU - GREMLIN Contacts

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SPEA - Arginine decarboxylase

UniProt:	P21885	Sequences: MSQHETPLYTGLKKHASRQPVQFHIPGHKKGAGMDPEFRQFIGENALSIDLINIEPLDDLHAPKGIIKQAQDLAAEAFGADHTFFSVQGTSGAIMTMVMAVCGPGDKIIIPRNVHKSIMTAIVFSGAVPIFIHPEIDNELGISHGITLESAKRALTEHPDAKGLLVINPTYFGVAADLKSIVELAHSFDVPVLVDEAHGVHIHFHDELPLSAMQAGADIAATSVHKLGGSLTQSSILNMREGLVSKDRVQSILSMLTTTSTSYLLLASLDVARKRLATEGRQLAEETLKLANQTRDRLNQIEGIYCVGSEILGSKAAYSYDPTKLIISVKSLGLTGHDVEKWLRESFNIEVELSDLYNILCIFTPGDSQNDADRLVEALTEIAQQMSEQDVTHQQTEVLLPEIPLLAMTPRDAFYANTEVIPLKEASGRIIAEFVMVYPPGIPIFIPGEIITEENISYIFKNLDAGLPVQGPEDSTLHMIRVIKEQKAIQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	490 (470)
Sequences:	2189 (1462)
Seq/√Len:	67.5

ECOLI - DCOR DCOS DCLZ ADIA LDCI
BACSU - SPEA YAAO

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
419_E	429_R	7.249	1.00
182_V	192_V	4.236	1.00
83_T	238_N	4.220	1.00
107_K	160_D	4.203	1.00
407_A	450_I	3.838	1.00
234_S	265_L	3.767	1.00
81_D	240_R	3.651	1.00
6_T	10_T	3.584	1.00
177_D	180_S	3.398	1.00
70_A	85_F	3.312	1.00
424_K	460_F	3.265	1.00
152_K	187_S	3.236	1.00
224_V	236_I	3.235	1.00
151_A	181_I	3.176	1.00
68_K	72_D	3.128	1.00
405_L	450_I	3.118	1.00
74_A	83_T	3.075	1.00
230_S	234_S	3.006	1.00
148_L	184_L	2.953	1.00
153_R	157_E	2.947	1.00
5_E	69_Q	2.934	1.00
427_S	456_I	2.924	1.00
86_S	93_A	2.794	1.00
75_A	80_A	2.793	1.00
427_S	453_E	2.764	1.00
97_M	193_L	2.739	1.00
453_E	457_S	2.701	1.00
106_D	162_K	2.656	1.00
156_T	188_F	2.554	1.00
22_Q	30_K	2.434	1.00
445_F	451_I	2.370	1.00
179_K	183_E	2.336	1.00
418_T	432_A	2.329	1.00
109_I	161_A	2.311	1.00
110_I	118_I	2.295	1.00
99_M	256_L	2.267	1.00
351_V	361_C	2.260	1.00
298_L	379_L	2.252	1.00
84_F	250_Q	2.243	1.00
155_L	190_V	2.212	1.00
422_P	425_E	2.197	1.00
196_E	212_A	2.171	1.00
107_K	128_V	2.113	1.00
90_T	235_S	2.112	1.00
172_F	355_D	2.080	1.00
107_K	158_H	2.070	1.00
164_L	185_A	2.061	1.00
97_M	219_I	2.049	1.00
346_S	381_E	2.036	1.00
109_I	132_I	2.035	1.00
152_K	156_T	2.029	1.00
11_G	66_I	2.015	1.00
324_K	360_L	2.014	1.00
213_M	220_A	1.991	1.00
294_T	372_A	1.987	1.00
12_L	267_A	1.978	1.00
90_T	221_A	1.947	1.00
193_L	221_A	1.947	1.00
8_L	266_L	1.934	1.00
346_S	385_Q	1.924	1.00
5_E	10_T	1.921	1.00
339_V	382_I	1.919	1.00
200_V	227_L	1.909	1.00
108_I	163_G	1.860	1.00
222_T	238_N	1.858	1.00
344_R	350_E	1.838	1.00
23_F	375_L	1.825	1.00
86_S	92_G	1.821	1.00
327_I	379_L	1.819	1.00
129_P	410_P	1.816	1.00
70_A	270_D	1.807	1.00
275_R	283_L	1.802	1.00
102_C	127_A	1.790	1.00
219_I	249_V	1.786	1.00
367_D	371_D	1.781	1.00
69_Q	72_D	1.780	1.00
421_I	426_A	1.778	1.00
351_V	359_I	1.771	1.00
102_C	106_D	1.760	1.00
74_A	78_F	1.748	1.00
74_A	236_I	1.747	1.00
326_I	360_L	1.734	1.00
135_E	150_S	1.732	1.00
76_E	277_A	1.728	1.00
118_I	165_L	1.710	1.00
191_P	243_L	1.692	0.99
304_I	379_L	1.677	0.99
82_H	250_Q	1.661	0.99
185_A	192_V	1.658	0.99
81_D	241_E	1.632	0.99
297_R	380_T	1.629	0.99
294_T	376_V	1.626	0.99
100_A	249_V	1.621	0.99
290_L	369_Q	1.618	0.99
92_G	256_L	1.600	0.99
369_Q	373_D	1.593	0.99
293_Q	369_Q	1.590	0.99
231_L	264_L	1.579	0.99
270_D	273_R	1.573	0.99
73_L	273_R	1.560	0.99
274_K	278_T	1.526	0.99
9_Y	271_V	1.526	0.99
291_A	363_F	1.513	0.99
104_P	126_G	1.510	0.99
155_L	188_F	1.505	0.99
96_T	253_L	1.504	0.99
301_I	383_A	1.491	0.99
355_D	358_N	1.465	0.99
13_K	17_S	1.459	0.98
363_F	372_A	1.457	0.98
21_V	349_I	1.457	0.98
292_N	322_P	1.442	0.98
168_N	176_A	1.437	0.98
186_H	218_D	1.432	0.98
97_M	221_A	1.424	0.98
93_A	253_L	1.420	0.98
82_H	246_K	1.420	0.98
46_A	264_L	1.416	0.98
334_L	339_V	1.413	0.98
107_K	130_I	1.403	0.98
239_M	246_K	1.403	0.98
189_D	243_L	1.401	0.98
42_I	46_A	1.394	0.98
135_E	147_T	1.392	0.98
110_I	122_I	1.391	0.98
193_L	219_I	1.383	0.98
51_L	57_L	1.372	0.98
178_L	192_V	1.368	0.98
58_D	63_P	1.368	0.98
85_F	270_D	1.366	0.98
325_L	363_F	1.363	0.98
227_L	362_I	1.360	0.98
231_L	268_S	1.350	0.97
10_T	14_K	1.348	0.97
291_A	295_R	1.338	0.97
196_E	222_T	1.335	0.97
102_C	163_G	1.317	0.97
18_R	348_N	1.309	0.97
86_S	253_L	1.306	0.97
108_I	165_L	1.304	0.97
294_T	325_L	1.303	0.97
411_R	415_Y	1.303	0.97
287_T	363_F	1.300	0.97
304_I	327_I	1.294	0.97
126_G	411_R	1.281	0.96
158_H	161_A	1.273	0.96
119_M	131_F	1.272	0.96
166_V	194_V	1.262	0.96
210_L	215_A	1.262	0.96
83_T	236_I	1.259	0.96
285_E	289_K	1.257	0.96
421_I	429_R	1.257	0.96
179_K	210_L	1.253	0.96
81_D	246_K	1.241	0.96
70_A	273_R	1.235	0.96
297_R	300_Q	1.229	0.96
342_W	382_I	1.221	0.95
99_M	125_S	1.219	0.95
131_F	446_I	1.209	0.95
122_I	129_P	1.205	0.95
206_D	281_R	1.197	0.95
140_L	307_V	1.183	0.95
239_M	249_V	1.178	0.94
184_L	188_F	1.176	0.94
94_I	111_P	1.174	0.94
180_S	183_E	1.173	0.94
132_I	151_A	1.171	0.94
182_V	215_A	1.171	0.94
132_I	150_S	1.171	0.94
180_S	184_L	1.170	0.94
297_R	376_V	1.167	0.94
328_S	358_N	1.165	0.94
152_K	180_S	1.162	0.94
77_A	273_R	1.160	0.94
25_I	362_I	1.157	0.94
183_E	187_S	1.155	0.94
185_A	190_V	1.146	0.94
236_I	269_L	1.145	0.93
29_K	367_D	1.137	0.93
163_G	190_V	1.134	0.93
434_F	447_P	1.130	0.93
182_V	186_H	1.130	0.93
340_E	354_S	1.129	0.93
98_V	165_L	1.111	0.92
279_E	282_Q	1.100	0.92
151_A	159_P	1.099	0.92
292_N	296_D	1.089	0.92
35_D	274_K	1.085	0.92
303_G	383_A	1.075	0.91
137_D	144_H	1.074	0.91
113_N	170_T	1.074	0.91
58_D	67_I	1.074	0.91
374_R	378_A	1.071	0.91
67_I	71_Q	1.071	0.91
8_L	66_I	1.067	0.91
276_L	284_A	1.066	0.91
298_L	304_I	1.061	0.91
202_I	209_P	1.059	0.90
224_V	269_L	1.059	0.90
200_V	228_G	1.057	0.90
205_H	288_L	1.054	0.90
14_K	17_S	1.051	0.90
462_N	467_L	1.050	0.90
178_L	182_V	1.049	0.90
147_T	150_S	1.046	0.90
288_L	322_P	1.046	0.90
91_S	95_M	1.046	0.90
152_K	184_L	1.046	0.90
88_Q	233_Q	1.044	0.90
34_M	47_L	1.042	0.90
208_L	323_T	1.039	0.90
334_L	386_M	1.037	0.90
353_L	360_L	1.031	0.89
87_V	258_T	1.027	0.89
81_D	242_G	1.026	0.89
407_A	430_I	1.026	0.89
131_F	406_L	1.023	0.89
286_E	289_K	1.022	0.89
294_T	298_L	1.019	0.89
108_I	122_I	1.009	0.88
205_H	285_E	1.006	0.88
203_H	211_S	1.004	0.88
409_T	412_D	1.004	0.88
15_H	350_E	1.003	0.88
7_P	273_R	1.002	0.88
53_N	261_T	0.999	0.88
25_I	52_I	0.996	0.88
104_P	411_R	0.994	0.87
309_S	319_S	0.991	0.87
103_G	106_D	0.985	0.87
452_T	455_N	0.982	0.87
172_F	358_N	0.980	0.87
21_V	374_R	0.976	0.87
20_P	350_E	0.975	0.86
77_A	277_A	0.970	0.86
8_L	67_I	0.962	0.86
74_A	85_F	0.961	0.86
210_L	214_Q	0.961	0.86
228_G	276_L	0.957	0.85
342_W	346_S	0.956	0.85
336_G	359_I	0.955	0.85
123_V	410_P	0.955	0.85
204_F	276_L	0.954	0.85
435_V	445_F	0.951	0.85
459_I	469_V	0.948	0.85
6_T	274_K	0.939	0.84
425_E	454_E	0.936	0.84
281_R	285_E	0.934	0.84
93_A	221_A	0.932	0.84
61_H	87_V	0.932	0.84
9_Y	270_D	0.930	0.84
87_V	325_L	0.921	0.83
128_V	409_T	0.920	0.83
232_T	262_S	0.919	0.83
339_V	359_I	0.918	0.83
380_T	384_Q	0.917	0.83
241_E	244_V	0.913	0.83
114_V	167_I	0.913	0.83
283_L	365_P	0.912	0.83
208_L	259_T	0.912	0.83
104_P	415_Y	0.910	0.82
80_A	213_M	0.910	0.82
112_R	449_E	0.905	0.82
340_E	351_V	0.904	0.82
36_P	40_Q	0.904	0.82
15_H	20_P	0.898	0.82
336_G	354_S	0.896	0.81
324_K	362_I	0.894	0.81
410_P	413_A	0.893	0.81
150_S	153_R	0.891	0.81
114_V	131_F	0.890	0.81
7_P	73_L	0.890	0.81
184_L	187_S	0.887	0.81
230_S	272_A	0.885	0.81
21_V	371_D	0.883	0.80
171_Y	352_E	0.875	0.80
22_Q	29_K	0.874	0.80
41_F	45_N	0.874	0.80
94_I	117_S	0.871	0.80
205_H	208_L	0.868	0.79
95_M	256_L	0.868	0.79
335_T	338_D	0.867	0.79
383_A	386_M	0.867	0.79
229_G	275_R	0.866	0.79
313_G	316_A	0.863	0.79
169_P	199_G	0.862	0.79
299_N	308_G	0.860	0.79
408_M	416_A	0.860	0.79
103_G	248_R	0.857	0.78
55_E	344_R	0.855	0.78
259_T	280_G	0.854	0.78
15_H	54_I	0.854	0.78
437_V	462_N	0.854	0.78
86_S	237_L	0.854	0.78
327_I	361_C	0.853	0.78
14_K	18_R	0.852	0.78
10_T	37_E	0.848	0.78
164_L	192_V	0.846	0.78
340_E	350_E	0.846	0.78
98_V	108_I	0.834	0.77
87_V	92_G	0.832	0.76
58_D	232_T	0.828	0.76
224_V	238_N	0.823	0.76
207_E	285_E	0.823	0.76
213_M	240_R	0.822	0.75
293_Q	297_R	0.822	0.75
84_F	239_M	0.815	0.75
290_L	372_A	0.815	0.75
113_N	134_P	0.814	0.75
11_G	14_K	0.812	0.75
92_G	257_T	0.808	0.74
93_A	257_T	0.806	0.74
71_Q	75_A	0.798	0.73
116_K	470_Q	0.795	0.73
83_T	222_T	0.795	0.73
230_S	265_L	0.793	0.73
397_E	400_L	0.789	0.72
337_H	467_L	0.788	0.72
155_L	184_L	0.787	0.72
220_A	238_N	0.785	0.72
404_P	410_P	0.783	0.72
241_E	246_K	0.782	0.72
26_P	50_D	0.778	0.71
122_I	127_A	0.777	0.71
77_A	204_F	0.777	0.71
109_I	154_A	0.776	0.71
132_I	146_I	0.773	0.71
219_I	244_V	0.769	0.71
368_S	371_D	0.765	0.70
146_I	166_V	0.765	0.70
377_E	381_E	0.765	0.70
94_I	118_I	0.764	0.70
95_M	120_T	0.764	0.70
25_I	232_T	0.763	0.70
25_I	53_N	0.761	0.70
408_M	412_D	0.760	0.70
406_L	409_T	0.760	0.70
47_L	231_L	0.760	0.70
267_A	270_D	0.756	0.69
203_H	214_Q	0.755	0.69
340_E	344_R	0.754	0.69
85_F	269_L	0.753	0.69
250_Q	253_L	0.750	0.69
65_G	69_Q	0.749	0.69
106_D	128_V	0.746	0.68
11_G	57_L	0.745	0.68
20_P	348_N	0.745	0.68
297_R	373_D	0.742	0.68
329_V	333_G	0.741	0.68
170_T	233_Q	0.740	0.68
408_M	413_A	0.740	0.68
19_Q	348_N	0.738	0.67
224_V	227_L	0.737	0.67
422_P	453_E	0.736	0.67
52_I	354_S	0.734	0.67
433_E	474_D	0.733	0.67
323_T	362_I	0.733	0.67
54_I	57_L	0.732	0.67
85_F	273_R	0.732	0.67
29_K	324_K	0.729	0.66
96_T	257_T	0.729	0.66
109_I	150_S	0.727	0.66
282_Q	286_E	0.726	0.66
400_L	403_I	0.725	0.66
73_L	77_A	0.725	0.66
88_Q	92_G	0.725	0.66
194_V	217_A	0.723	0.66
155_L	164_L	0.722	0.66
49_I	264_L	0.720	0.65
280_G	283_L	0.719	0.65
110_I	165_L	0.717	0.65
9_Y	49_I	0.717	0.65
116_K	120_T	0.715	0.65
438_Y	441_G	0.712	0.65
22_Q	25_I	0.712	0.65
9_Y	41_F	0.711	0.64
38_F	271_V	0.710	0.64
213_M	222_T	0.710	0.64
123_V	413_A	0.706	0.64
381_E	384_Q	0.706	0.64
25_I	54_I	0.705	0.64
364_T	367_D	0.704	0.64
184_L	192_V	0.703	0.64
24_H	54_I	0.701	0.63
111_P	167_I	0.700	0.63
182_V	185_A	0.700	0.63
152_K	188_F	0.699	0.63
293_Q	373_D	0.697	0.63
6_T	9_Y	0.697	0.63
155_L	161_A	0.697	0.63
73_L	277_A	0.696	0.63
283_L	366_G	0.696	0.63
13_K	40_Q	0.696	0.63
111_P	114_V	0.693	0.62
198_H	232_T	0.693	0.62
246_K	249_V	0.692	0.62
430_I	450_I	0.692	0.62
177_D	316_A	0.689	0.62
269_L	273_R	0.689	0.62
228_G	261_T	0.686	0.62
337_H	354_S	0.683	0.61
60_L	263_Y	0.683	0.61
431_I	472_P	0.681	0.61
53_N	198_H	0.681	0.61
411_R	414_F	0.681	0.61
25_I	262_S	0.680	0.61
472_P	475_S	0.680	0.61
84_F	100_A	0.680	0.61
163_G	193_L	0.679	0.61
137_D	140_L	0.679	0.61
234_S	268_S	0.676	0.61
417_N	429_R	0.676	0.61
287_T	291_A	0.676	0.61
109_I	164_L	0.674	0.60
367_D	372_A	0.673	0.60
305_Y	328_S	0.673	0.60
172_F	353_L	0.671	0.60
101_V	191_P	0.671	0.60
168_N	202_I	0.670	0.60
334_L	382_I	0.666	0.59
431_I	445_F	0.666	0.59
301_I	304_I	0.666	0.59
444_I	459_I	0.665	0.59
175_A	209_P	0.662	0.59
148_L	427_S	0.662	0.59
208_L	288_L	0.662	0.59
117_S	438_Y	0.662	0.59
151_A	164_L	0.661	0.59
172_F	360_L	0.660	0.59
132_I	154_A	0.660	0.59
343_L	379_L	0.659	0.59
161_A	190_V	0.659	0.59
232_T	263_Y	0.659	0.59
24_H	263_Y	0.659	0.59
28_H	50_D	0.659	0.59
53_N	93_A	0.658	0.59
155_L	159_P	0.658	0.59
176_A	181_I	0.656	0.58
142_I	170_T	0.656	0.58
72_D	282_Q	0.655	0.58
398_V	402_E	0.655	0.58
148_L	152_K	0.654	0.58
199_G	262_S	0.654	0.58
237_L	249_V	0.654	0.58
126_G	410_P	0.654	0.58
53_N	263_Y	0.653	0.58
144_H	172_F	0.653	0.58
166_V	178_L	0.652	0.58
91_S	259_T	0.650	0.58
15_H	30_K	0.650	0.58
94_I	198_H	0.649	0.57
95_M	116_K	0.648	0.57
71_Q	253_L	0.648	0.57
451_I	455_N	0.648	0.57
140_L	358_N	0.647	0.57
296_D	300_Q	0.645	0.57
130_I	158_H	0.645	0.57
9_Y	13_K	0.644	0.57
52_I	61_H	0.644	0.57
413_A	416_A	0.644	0.57
123_V	447_P	0.643	0.57
310_E	313_G	0.642	0.57
86_S	221_A	0.641	0.57
288_L	292_N	0.641	0.57
52_I	263_Y	0.640	0.56
232_T	352_E	0.639	0.56
224_V	228_G	0.639	0.56
95_M	259_T	0.639	0.56
39_R	44_E	0.638	0.56
253_L	259_T	0.637	0.56
20_P	344_R	0.636	0.56
80_A	240_R	0.635	0.56
290_L	294_T	0.633	0.56
253_L	257_T	0.632	0.55
287_T	323_T	0.630	0.55
253_L	262_S	0.630	0.55
286_E	290_L	0.630	0.55
198_H	253_L	0.629	0.55
120_T	339_V	0.626	0.55
64_K	325_L	0.625	0.55
73_L	76_E	0.623	0.54
31_G	57_L	0.622	0.54
105_G	453_E	0.620	0.54
168_N	182_V	0.620	0.54
79_G	203_H	0.619	0.54
373_D	377_E	0.617	0.54
148_L	151_A	0.617	0.54
208_L	227_L	0.614	0.53
270_D	276_L	0.614	0.53
38_F	42_I	0.614	0.53
205_H	209_P	0.614	0.53
168_N	213_M	0.613	0.53
77_A	270_D	0.613	0.53
338_D	341_K	0.612	0.53
456_I	460_F	0.612	0.53
224_V	273_R	0.611	0.53
15_H	18_R	0.609	0.53
87_V	198_H	0.608	0.53
377_E	389_Q	0.608	0.53
123_V	259_T	0.606	0.52
79_G	214_Q	0.606	0.52
52_I	262_S	0.606	0.52
93_A	198_H	0.605	0.52
102_C	109_I	0.605	0.52
166_V	327_I	0.605	0.52
435_V	459_I	0.604	0.52
98_V	121_A	0.602	0.52
44_E	48_S	0.601	0.52
54_I	324_K	0.600	0.52
24_H	61_H	0.599	0.52
119_M	446_I	0.599	0.52
458_Y	462_N	0.599	0.52
27_G	232_T	0.598	0.51
283_L	287_T	0.598	0.51
149_E	152_K	0.598	0.51
462_N	469_V	0.598	0.51
377_E	384_Q	0.598	0.51
167_I	436_M	0.598	0.51
84_F	246_K	0.597	0.51
148_L	164_L	0.596	0.51
341_K	345_E	0.596	0.51
412_D	416_A	0.595	0.51
114_V	165_L	0.594	0.51
116_K	436_M	0.594	0.51
413_A	447_P	0.593	0.51
199_G	232_T	0.592	0.51
98_V	101_V	0.592	0.51
159_P	162_K	0.592	0.51
13_K	49_I	0.591	0.51
51_L	54_I	0.590	0.50
203_H	276_L	0.590	0.50
24_H	52_I	0.590	0.50
64_K	258_T	0.590	0.50
395_Q	398_V	0.589	0.50
121_A	125_S	0.588	0.50
71_Q	91_S	0.588	0.50
111_P	176_A	0.587	0.50
78_F	203_H	0.587	0.50
154_A	159_P	0.587	0.50
338_D	342_W	0.587	0.50
422_P	460_F	0.585	0.50
58_D	66_I	0.585	0.50
320_Y	326_I	0.584	0.50
204_F	259_T	0.583	0.50
457_S	460_F	0.582	0.50
86_S	257_T	0.582	0.50
169_P	201_H	0.581	0.49
112_R	438_Y	0.581	0.49
436_M	470_Q	0.581	0.49
52_I	60_L	0.581	0.49
116_K	172_F	0.580	0.49
87_V	257_T	0.578	0.49
146_I	151_A	0.576	0.49
70_A	74_A	0.576	0.49
105_G	128_V	0.576	0.49
153_R	457_S	0.574	0.49
293_Q	376_V	0.574	0.49
381_E	385_Q	0.571	0.48
254_S	258_T	0.571	0.48
78_F	236_I	0.570	0.48
325_L	375_L	0.570	0.48
54_I	262_S	0.569	0.48
156_T	249_V	0.569	0.48
96_T	198_H	0.569	0.48
378_A	382_I	0.568	0.48
234_S	264_L	0.567	0.48
199_G	202_I	0.566	0.48
120_T	255_M	0.564	0.47
396_T	400_L	0.563	0.47
68_K	379_L	0.563	0.47
148_L	180_S	0.563	0.47
151_A	154_A	0.563	0.47
299_N	306_C	0.563	0.47
123_V	414_F	0.562	0.47
345_E	457_S	0.562	0.47
129_P	406_L	0.561	0.47
170_T	174_V	0.560	0.47
280_G	323_T	0.559	0.47
123_V	251_S	0.558	0.47
429_R	432_A	0.557	0.47
222_T	261_T	0.554	0.46
25_I	29_K	0.554	0.46
334_L	338_D	0.554	0.46
24_H	470_Q	0.553	0.46
96_T	122_I	0.552	0.46
289_K	369_Q	0.551	0.46
57_L	269_L	0.550	0.46
107_K	161_A	0.549	0.46
348_N	435_V	0.549	0.46
207_E	292_N	0.548	0.46
72_D	389_Q	0.547	0.45
52_I	56_P	0.547	0.45
15_H	51_L	0.547	0.45
222_T	236_I	0.547	0.45
289_K	293_Q	0.546	0.45
25_I	51_L	0.546	0.45
454_E	457_S	0.546	0.45
60_L	258_T	0.546	0.45
37_E	274_K	0.546	0.45
175_A	319_S	0.545	0.45
175_A	202_I	0.544	0.45
87_V	182_V	0.544	0.45
370_N	378_A	0.544	0.45
100_A	252_I	0.544	0.45
212_A	217_A	0.543	0.45
297_R	377_E	0.543	0.45
286_E	460_F	0.543	0.45
59_D	259_T	0.542	0.45
16_A	48_S	0.542	0.45
58_D	350_E	0.542	0.45
71_Q	250_Q	0.542	0.45
121_A	295_R	0.542	0.45
194_V	212_A	0.541	0.45
398_V	401_P	0.541	0.45
232_T	264_L	0.539	0.44
299_N	305_Y	0.537	0.44
60_L	352_E	0.537	0.44
148_L	177_D	0.535	0.44
19_Q	374_R	0.534	0.44
88_Q	167_I	0.533	0.44
91_S	239_M	0.532	0.44
290_L	376_V	0.532	0.44
122_I	410_P	0.532	0.44
53_N	60_L	0.531	0.44
183_E	345_E	0.530	0.43
64_K	445_F	0.530	0.43
307_V	320_Y	0.530	0.43
25_I	352_E	0.530	0.43
294_T	363_F	0.530	0.43
54_I	353_L	0.529	0.43
42_I	49_I	0.529	0.43
207_E	289_K	0.529	0.43
68_K	369_Q	0.528	0.43
464_D	476_T	0.528	0.43
100_A	193_L	0.528	0.43
328_S	331_S	0.528	0.43
56_P	88_Q	0.527	0.43
202_I	211_S	0.526	0.43
171_Y	263_Y	0.526	0.43
460_F	463_L	0.525	0.43
319_S	322_P	0.525	0.43
26_P	352_E	0.524	0.43
233_Q	265_L	0.524	0.43
87_V	95_M	0.524	0.43
405_L	452_T	0.524	0.43
73_L	270_D	0.524	0.43
96_T	237_L	0.523	0.43
323_T	363_F	0.522	0.42
52_I	198_H	0.522	0.42
369_Q	460_F	0.522	0.42
98_V	102_C	0.522	0.42
232_T	266_L	0.522	0.42
445_F	459_I	0.522	0.42
52_I	266_L	0.522	0.42
375_L	382_I	0.521	0.42
97_M	163_G	0.520	0.42
27_G	50_D	0.520	0.42
175_A	375_L	0.520	0.42
163_G	191_P	0.520	0.42
53_N	352_E	0.520	0.42
330_K	357_Y	0.519	0.42
272_A	323_T	0.519	0.42
245_S	249_V	0.518	0.42
307_V	328_S	0.518	0.42
64_K	341_K	0.518	0.42
134_P	151_A	0.518	0.42
377_E	421_I	0.518	0.42
67_I	266_L	0.517	0.42
378_A	381_E	0.517	0.42
52_I	261_T	0.517	0.42
153_R	402_E	0.516	0.42
394_Q	397_E	0.515	0.42
74_A	269_L	0.515	0.42
183_E	186_H	0.514	0.42
92_G	253_L	0.514	0.42
166_V	181_I	0.514	0.42
25_I	353_L	0.514	0.42
58_D	62_A	0.513	0.41
338_D	388_E	0.513	0.41
216_G	442_I	0.513	0.41
116_K	355_D	0.512	0.41
129_P	332_L	0.512	0.41
274_K	277_A	0.512	0.41
197_A	226_K	0.512	0.41
94_I	166_V	0.510	0.41
52_I	58_D	0.510	0.41
148_L	166_V	0.509	0.41
18_R	388_E	0.509	0.41
393_H	425_E	0.506	0.41
55_E	354_S	0.506	0.41
33_G	275_R	0.506	0.41
24_H	261_T	0.505	0.40
94_I	221_A	0.505	0.40
25_I	350_E	0.505	0.40
88_Q	227_L	0.504	0.40
101_V	193_L	0.504	0.40
187_S	191_P	0.504	0.40
54_I	263_Y	0.504	0.40
231_L	235_S	0.504	0.40
61_H	198_H	0.504	0.40
78_F	83_T	0.504	0.40
435_V	469_V	0.502	0.40
120_T	436_M	0.502	0.40
431_I	434_F	0.502	0.40
52_I	324_K	0.500	0.40

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2vycA	5	0.9857	100	0.424	Contact Map
3n75A	4	0.9796	100	0.44	Contact Map
1c4kA	2	0.9939	100	0.446	Contact Map
2x3lA	2	0.8551	100	0.45	Contact Map
4q6rA	2	0.8245	100	0.742	Contact Map
3mc6A	2	0.7694	100	0.748	Contact Map
4w8iA	2	0.6898	100	0.77	Contact Map
3bc8A	3	0.7592	100	0.784	Contact Map
3hl2A	3	0.7653	100	0.789	Contact Map
1jg8A	4	0.6612	100	0.807	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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