IMDH - BACSU - GREMLIN Contacts

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IMDH - Inosine-5'-monophosphate dehydrogenase

UniProt:	P21879	Sequences: MWESKFSKEGLTFDDVLLVPAKSEVLPRDVDLSVELTKTLKLNIPVISAGMDTVTESAMAIAMARQGGLGIIHKNMSIEQQAEQVDKVKRSERGVITNPFFLTPDHQVFDAEHLMGKYRISGVPIVNNEEDQKLVGIITNRDLRFISDYSMKISDVMTKEELVTASVGTTLDEAEKILQKHKIEKLPLVDDQNKLKGLITIKDIEKVIEFPNSSKDIHGRLIVGAAVGVTGDTMTRVKKLVEANVDVIVIDTAHGHSQGVLNTVTKIRETYPELNIIAGNVATAEATRALIEAGADVVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKTIIADGGIKFSGDITKALAAGGHAVMLGSLLAGTSESPGETEIYQGRRFKVYRGMGSVAAMEKGSKDRYFQEENKKFVPEGIEGRTPYKGPVEETVYQLVGGLRSGMGYCGSKDLRALREEAQFIRMTGAGLRESHPHDVQITKESPNYTIS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	488 (472)
Sequences:	2843 (1082)
Seq/√Len:	49.8

ECOLI - IMDH GUAC
BACSU - IMDH GUAC
HALSA - IMDH

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
71_I	224_G	6.534	1.00
39_T	275_N	4.697	1.00
78_I	239_K	4.239	1.00
450_D	453_A	4.135	1.00
190_D	194_K	4.055	1.00
9_E	462_R	3.720	1.00
102_L	125_I	3.610	1.00
351_T	442_G	3.592	1.00
214_S	222_I	3.317	1.00
330_E	333_K	3.293	1.00
288_R	292_E	3.291	1.00
359_H	455_R	3.153	1.00
55_T	70_G	3.122	1.00
33_S	41_K	3.066	1.00
35_E	41_K	3.021	1.00
258_Q	262_N	2.931	1.00
354_L	439_L	2.869	1.00
165_A	188_L	2.861	1.00
24_E	258_Q	2.701	1.00
288_R	330_E	2.700	1.00
71_I	247_V	2.692	1.00
281_V	287_T	2.680	1.00
241_V	274_L	2.635	1.00
238_K	242_E	2.621	1.00
453_A	457_E	2.618	1.00
268_R	276_I	2.565	1.00
237_V	267_I	2.536	1.00
345_K	468_L	2.480	1.00
22_K	289_A	2.480	1.00
22_K	258_Q	2.460	1.00
451_L	455_R	2.414	1.00
286_A	327_C	2.397	1.00
287_T	327_C	2.387	1.00
449_K	453_A	2.377	1.00
8_K	326_D	2.370	1.00
46_V	432_V	2.370	1.00
285_E	459_Q	2.366	1.00
106_H	110_D	2.355	1.00
224_G	247_V	2.318	1.00
291_I	331_A	2.313	1.00
37_T	275_N	2.303	1.00
77_S	80_Q	2.266	1.00
287_T	291_I	2.266	1.00
281_V	327_C	2.263	1.00
84_Q	87_K	2.262	1.00
227_V	237_V	2.261	1.00
151_M	155_D	2.255	1.00
281_V	286_A	2.253	1.00
268_R	296_D	2.237	1.00
32_L	436_V	2.223	1.00
363_L	367_L	2.188	1.00
36_L	247_V	2.176	1.00
170_T	173_E	2.125	1.00
248_I	274_L	2.123	1.00
146_I	151_M	2.116	1.00
109_F	113_H	2.097	1.00
237_V	248_I	2.080	1.00
35_E	335_G	2.059	1.00
363_L	366_L	2.053	1.00
452_R	456_E	2.008	1.00
125_I	153_I	2.000	1.00
59_M	428_V	1.978	0.99
262_N	265_T	1.961	0.99
57_S	84_Q	1.955	0.99
69_L	247_V	1.940	0.99
102_L	111_A	1.936	0.99
36_L	277_I	1.928	0.99
102_L	153_I	1.913	0.99
452_R	455_R	1.908	0.99
418_I	476_V	1.901	0.99
233_T	263_T	1.899	0.99
109_F	150_S	1.887	0.99
103_T	106_H	1.887	0.99
350_I	361_V	1.864	0.99
351_T	454_L	1.858	0.99
395_A	419_E	1.848	0.99
289_A	292_E	1.826	0.99
331_A	338_I	1.822	0.99
166_S	191_D	1.774	0.99
287_T	338_I	1.769	0.99
111_A	138_I	1.765	0.99
267_I	276_I	1.757	0.99
252_T	260_V	1.688	0.98
250_I	264_V	1.685	0.98
63_M	432_V	1.682	0.98
264_V	278_A	1.680	0.98
238_K	270_T	1.675	0.98
85_V	245_V	1.666	0.98
176_K	180_K	1.663	0.98
105_D	152_K	1.655	0.98
44_I	436_V	1.652	0.98
104_P	135_V	1.649	0.98
152_K	155_D	1.626	0.98
102_L	106_H	1.623	0.98
284_A	330_E	1.615	0.98
238_K	271_Y	1.612	0.98
46_V	363_L	1.611	0.98
300_V	338_I	1.609	0.98
47_I	360_A	1.597	0.98
247_V	277_I	1.594	0.98
37_T	297_V	1.571	0.97
354_L	451_L	1.566	0.97
253_A	445_Y	1.550	0.97
113_H	117_K	1.549	0.97
288_R	333_K	1.549	0.97
71_I	249_V	1.545	0.97
38_K	337_T	1.540	0.97
166_S	169_T	1.513	0.97
33_S	43_N	1.511	0.97
133_K	194_K	1.511	0.97
366_L	435_L	1.510	0.97
276_I	295_A	1.491	0.96
291_I	336_K	1.483	0.96
232_D	235_T	1.479	0.96
287_T	331_A	1.465	0.96
332_R	455_R	1.448	0.96
105_D	154_S	1.447	0.96
367_L	428_V	1.442	0.96
36_L	224_G	1.440	0.96
80_Q	84_Q	1.437	0.96
250_I	278_A	1.434	0.95
442_G	454_L	1.428	0.95
46_V	367_L	1.419	0.95
167_V	196_K	1.418	0.95
448_S	458_A	1.410	0.95
47_I	277_I	1.403	0.95
165_A	169_T	1.402	0.95
138_I	156_V	1.396	0.95
261_L	265_T	1.395	0.95
413_F	441_S	1.395	0.95
325_Y	329_T	1.394	0.95
111_A	115_M	1.362	0.94
284_A	329_T	1.362	0.94
36_L	360_A	1.361	0.94
278_A	295_A	1.354	0.94
282_A	318_V	1.350	0.94
288_R	334_H	1.344	0.94
292_E	334_H	1.341	0.94
173_E	176_K	1.339	0.93
48_S	55_T	1.328	0.93
237_V	271_Y	1.313	0.93
377_T	384_R	1.293	0.92
354_L	455_R	1.286	0.92
127_N	135_V	1.285	0.92
24_E	449_K	1.284	0.92
291_I	334_H	1.280	0.92
324_I	340_A	1.270	0.92
39_T	273_E	1.244	0.91
371_S	424_Y	1.242	0.91
38_K	296_D	1.237	0.90
331_A	334_H	1.237	0.90
245_V	274_L	1.224	0.90
103_T	135_V	1.224	0.90
108_V	146_I	1.221	0.90
297_V	360_A	1.220	0.90
85_V	225_A	1.210	0.89
179_Q	182_K	1.209	0.89
418_I	482_S	1.209	0.89
74_K	259_G	1.205	0.89
312_V	468_L	1.197	0.89
337_T	359_H	1.195	0.89
354_L	454_L	1.195	0.89
448_S	453_A	1.194	0.89
59_M	367_L	1.194	0.89
120_I	123_V	1.192	0.89
371_S	427_P	1.185	0.88
26_L	259_G	1.177	0.88
36_L	47_I	1.172	0.88
169_T	173_E	1.171	0.88
328_A	338_I	1.169	0.88
443_M	451_L	1.148	0.87
284_A	288_R	1.144	0.87
107_Q	152_K	1.144	0.87
147_S	176_K	1.143	0.87
148_D	151_M	1.140	0.86
454_L	458_A	1.140	0.86
36_L	297_V	1.140	0.86
235_T	238_K	1.130	0.86
32_L	440_R	1.127	0.86
356_A	460_F	1.123	0.86
31_D	41_K	1.121	0.85
29_D	449_K	1.118	0.85
217_I	222_I	1.117	0.85
250_I	267_I	1.117	0.85
48_S	63_M	1.115	0.85
48_S	70_G	1.115	0.85
350_I	435_L	1.113	0.85
287_T	330_E	1.103	0.85
266_K	270_T	1.094	0.84
38_K	336_K	1.091	0.84
355_A	458_A	1.086	0.84
234_M	266_K	1.086	0.84
37_T	247_V	1.083	0.83
39_T	217_I	1.081	0.83
18_L	446_C	1.081	0.83
100_F	125_I	1.078	0.83
34_V	44_I	1.071	0.83
250_I	260_V	1.067	0.83
112_E	149_Y	1.060	0.82
50_G	299_K	1.056	0.82
127_N	131_D	1.047	0.81
13_F	324_I	1.040	0.81
110_D	113_H	1.039	0.81
473_P	476_V	1.039	0.81
10_G	461_I	1.038	0.81
21_A	457_E	1.037	0.81
46_V	436_V	1.035	0.81
123_V	153_I	1.031	0.80
11_L	462_R	1.020	0.80
127_N	194_K	1.019	0.79
291_I	330_E	1.018	0.79
329_T	333_K	1.018	0.79
142_D	187_P	1.014	0.79
297_V	337_T	1.011	0.79
367_L	432_V	1.009	0.79
57_S	87_K	1.008	0.79
248_I	252_T	1.006	0.79
291_I	333_K	1.004	0.78
298_V	331_A	1.004	0.78
237_V	274_L	1.004	0.78
232_D	263_T	1.003	0.78
423_P	426_G	1.003	0.78
65_R	91_S	0.999	0.78
268_R	295_A	0.999	0.78
265_T	269_E	0.993	0.78
171_L	175_E	0.993	0.78
367_L	467_G	0.987	0.77
189_V	193_N	0.987	0.77
21_A	459_Q	0.982	0.77
359_H	452_R	0.981	0.77
131_D	194_K	0.978	0.77
107_Q	110_D	0.977	0.77
174_A	186_L	0.967	0.76
47_I	69_L	0.967	0.76
178_L	186_L	0.962	0.75
332_R	456_E	0.961	0.75
448_S	473_P	0.954	0.75
11_L	321_I	0.952	0.75
284_A	326_D	0.949	0.74
167_V	191_D	0.948	0.74
312_V	473_P	0.946	0.74
165_A	177_I	0.946	0.74
264_V	295_A	0.942	0.74
287_T	298_V	0.935	0.73
265_T	292_E	0.933	0.73
225_A	245_V	0.931	0.73
327_C	330_E	0.930	0.73
363_L	435_L	0.929	0.73
102_L	110_D	0.928	0.73
205_E	209_E	0.928	0.73
227_V	248_I	0.924	0.72
95_V	188_L	0.924	0.72
361_V	367_L	0.923	0.72
166_S	173_E	0.922	0.72
83_E	86_D	0.921	0.72
330_E	334_H	0.919	0.72
104_P	154_S	0.917	0.72
174_A	187_P	0.916	0.72
370_T	428_V	0.915	0.72
66_Q	429_E	0.911	0.71
100_F	120_I	0.909	0.71
448_S	457_E	0.906	0.71
227_V	233_T	0.899	0.70
354_L	458_A	0.896	0.70
256_H	289_A	0.895	0.70
261_L	289_A	0.895	0.70
282_A	302_I	0.894	0.70
274_L	296_D	0.893	0.70
23_S	254_H	0.893	0.70
268_R	272_P	0.889	0.69
104_P	138_I	0.887	0.69
321_I	458_A	0.885	0.69
40_L	222_I	0.884	0.69
332_R	359_H	0.883	0.69
80_Q	83_E	0.881	0.69
264_V	276_I	0.880	0.69
21_A	448_S	0.877	0.68
19_V	23_S	0.875	0.68
163_V	181_H	0.869	0.68
324_I	338_I	0.866	0.67
237_V	241_V	0.865	0.67
74_K	400_G	0.860	0.67
69_L	360_A	0.859	0.67
95_V	101_F	0.855	0.66
119_R	140_N	0.855	0.66
463_M	468_L	0.854	0.66
102_L	114_L	0.854	0.66
38_K	275_N	0.849	0.66
331_A	359_H	0.848	0.66
109_F	149_Y	0.846	0.66
165_A	187_P	0.843	0.65
35_E	38_K	0.843	0.65
264_V	286_A	0.841	0.65
275_N	297_V	0.839	0.65
30_V	450_D	0.836	0.65
110_D	123_V	0.835	0.65
441_S	444_G	0.834	0.65
227_V	250_I	0.834	0.65
328_A	335_G	0.834	0.65
261_L	278_A	0.830	0.64
127_N	133_K	0.829	0.64
413_F	433_Y	0.826	0.64
53_T	56_E	0.826	0.64
281_V	298_V	0.824	0.64
281_V	338_I	0.820	0.63
108_V	151_M	0.819	0.63
363_L	428_V	0.819	0.63
314_A	471_S	0.817	0.63
380_Y	421_R	0.817	0.63
428_V	432_V	0.816	0.63
427_P	430_E	0.816	0.63
46_V	63_M	0.815	0.63
126_V	132_Q	0.814	0.63
104_P	126_V	0.811	0.62
106_H	123_V	0.809	0.62
171_L	177_I	0.803	0.62
103_T	127_N	0.802	0.61
282_A	327_C	0.802	0.61
134_L	185_K	0.798	0.61
98_N	195_L	0.796	0.61
327_C	338_I	0.791	0.60
234_M	270_T	0.791	0.60
262_N	266_K	0.790	0.60
295_A	298_V	0.787	0.60
59_M	63_M	0.785	0.60
16_V	356_A	0.782	0.59
105_D	127_N	0.780	0.59
322_T	326_D	0.775	0.59
112_E	116_G	0.773	0.59
82_A	239_K	0.772	0.59
233_T	237_V	0.768	0.58
229_V	413_F	0.766	0.58
322_T	325_Y	0.766	0.58
112_E	138_I	0.765	0.58
261_L	286_A	0.765	0.58
205_E	345_K	0.764	0.58
175_E	207_V	0.763	0.58
21_A	446_C	0.760	0.57
230_T	233_T	0.758	0.57
239_K	242_E	0.753	0.57
71_I	253_A	0.752	0.57
378_E	421_R	0.752	0.57
97_T	218_H	0.749	0.56
28_R	408_E	0.745	0.56
65_R	430_E	0.745	0.56
19_V	459_Q	0.744	0.56
241_V	245_V	0.744	0.56
467_G	471_S	0.744	0.56
263_T	266_K	0.743	0.56
222_I	247_V	0.742	0.55
154_S	159_K	0.742	0.55
13_F	302_I	0.742	0.55
331_A	468_L	0.741	0.55
28_R	409_E	0.740	0.55
167_V	190_D	0.736	0.55
448_S	456_E	0.736	0.55
102_L	473_P	0.735	0.55
345_K	400_G	0.734	0.55
63_M	367_L	0.730	0.54
49_A	299_K	0.729	0.54
43_N	214_S	0.728	0.54
171_L	204_I	0.727	0.54
115_M	120_I	0.727	0.54
248_I	314_A	0.726	0.54
83_E	117_K	0.722	0.53
321_I	356_A	0.722	0.53
10_G	322_T	0.720	0.53
327_C	331_A	0.719	0.53
59_M	432_V	0.719	0.53
312_V	461_I	0.717	0.53
115_M	123_V	0.716	0.53
41_K	222_I	0.714	0.53
193_N	196_K	0.713	0.53
72_I	85_V	0.711	0.52
347_S	435_L	0.710	0.52
175_E	182_K	0.708	0.52
350_I	363_L	0.708	0.52
233_T	252_T	0.707	0.52
261_L	293_A	0.706	0.52
115_M	186_L	0.706	0.52
86_D	196_K	0.705	0.52
351_T	354_L	0.701	0.51
191_D	194_K	0.700	0.51
34_V	451_L	0.700	0.51
370_T	431_T	0.700	0.51
82_A	86_D	0.697	0.51
284_A	328_A	0.697	0.51
34_V	277_I	0.694	0.51
36_L	69_L	0.694	0.51
250_I	276_I	0.693	0.51
90_R	140_N	0.693	0.51
446_C	458_A	0.692	0.50
174_A	199_I	0.691	0.50
229_V	233_T	0.691	0.50
142_D	157_M	0.691	0.50
110_D	153_I	0.689	0.50
95_V	100_F	0.687	0.50
327_C	359_H	0.687	0.50
81_Q	245_V	0.683	0.49
32_L	439_L	0.681	0.49
36_L	322_T	0.680	0.49
411_K	430_E	0.680	0.49
146_I	149_Y	0.679	0.49
464_T	467_G	0.679	0.49
304_P	309_T	0.679	0.49
90_R	385_F	0.678	0.49
82_A	243_A	0.677	0.49
228_G	232_D	0.677	0.49
77_S	425_K	0.676	0.49
66_Q	210_F	0.676	0.49
114_L	123_V	0.676	0.49
25_V	30_V	0.674	0.49
74_K	302_I	0.673	0.48
134_L	189_V	0.673	0.48
250_I	287_T	0.673	0.48
112_E	143_L	0.672	0.48
169_T	177_I	0.672	0.48
252_T	286_A	0.671	0.48
65_R	473_P	0.671	0.48
32_L	44_I	0.670	0.48
230_T	411_K	0.670	0.48
326_D	329_T	0.670	0.48
132_Q	194_K	0.669	0.48
19_V	302_I	0.668	0.48
19_V	446_C	0.667	0.48
62_A	432_V	0.667	0.48
229_V	264_V	0.666	0.48
35_E	359_H	0.665	0.48
112_E	148_D	0.662	0.47
237_V	276_I	0.661	0.47
166_S	196_K	0.659	0.47
19_V	46_V	0.659	0.47
314_A	469_R	0.658	0.47
93_R	418_I	0.658	0.47
37_T	277_I	0.658	0.47
270_T	273_E	0.658	0.47
165_A	201_I	0.657	0.47
174_A	198_L	0.656	0.47
296_D	336_K	0.656	0.47
12_T	321_I	0.655	0.47
234_M	237_V	0.653	0.46
420_G	476_V	0.653	0.46
350_I	439_L	0.653	0.46
122_G	185_K	0.651	0.46
378_E	480_K	0.651	0.46
91_S	210_F	0.650	0.46
379_I	384_R	0.650	0.46
40_L	247_V	0.648	0.46
414_V	441_S	0.648	0.46
108_V	156_V	0.646	0.46
387_V	433_Y	0.645	0.46
229_V	263_T	0.645	0.46
36_L	42_L	0.644	0.46
103_T	152_K	0.642	0.45
83_E	87_K	0.642	0.45
62_A	428_V	0.640	0.45
106_H	154_S	0.638	0.45
103_T	126_V	0.638	0.45
142_D	158_T	0.638	0.45
50_G	287_T	0.637	0.45
292_E	333_K	0.637	0.45
49_A	424_Y	0.637	0.45
252_T	259_G	0.632	0.44
264_V	367_L	0.632	0.44
112_E	135_V	0.632	0.44
312_V	471_S	0.631	0.44
38_K	297_V	0.630	0.44
69_L	297_V	0.630	0.44
91_S	118_Y	0.630	0.44
106_H	153_I	0.630	0.44
241_V	271_Y	0.629	0.44
292_E	330_E	0.628	0.44
63_M	69_L	0.627	0.44
403_D	407_Q	0.627	0.44
101_F	188_L	0.627	0.44
103_T	154_S	0.625	0.44
139_T	158_T	0.624	0.43
345_K	383_R	0.624	0.43
238_K	241_V	0.623	0.43
235_T	239_K	0.623	0.43
38_K	47_I	0.622	0.43
259_G	262_N	0.622	0.43
141_R	185_K	0.620	0.43
258_Q	265_T	0.620	0.43
176_K	276_I	0.617	0.43
86_D	117_K	0.616	0.43
187_P	195_L	0.616	0.43
117_K	265_T	0.615	0.43
96_I	177_I	0.614	0.42
253_A	314_A	0.613	0.42
245_V	248_I	0.612	0.42
286_A	289_A	0.611	0.42
111_A	153_I	0.611	0.42
275_N	337_T	0.610	0.42
297_V	336_K	0.610	0.42
314_A	463_M	0.609	0.42
75_N	392_G	0.609	0.42
13_F	121_S	0.608	0.42
174_A	378_E	0.608	0.42
13_F	340_A	0.608	0.42
40_L	275_N	0.605	0.42
124_P	195_L	0.604	0.41
288_R	291_I	0.603	0.41
249_V	253_A	0.603	0.41
36_L	71_I	0.603	0.41
228_G	237_V	0.602	0.41
95_V	378_E	0.602	0.41
34_V	360_A	0.602	0.41
127_N	132_Q	0.600	0.41
19_V	326_D	0.599	0.41
268_R	297_V	0.598	0.41
101_F	123_V	0.596	0.41
166_S	192_Q	0.595	0.41
392_G	405_Y	0.594	0.40
378_E	385_F	0.593	0.40
62_A	174_A	0.592	0.40
100_F	123_V	0.592	0.40
106_H	125_I	0.591	0.40
404_R	420_G	0.590	0.40
169_T	174_A	0.590	0.40
27_P	75_N	0.586	0.40
258_Q	261_L	0.586	0.40
366_L	431_T	0.585	0.40
402_K	409_E	0.585	0.40
234_M	263_T	0.585	0.40
94_G	215_K	0.584	0.40
282_A	389_R	0.584	0.40
141_R	184_E	0.583	0.39
397_M	405_Y	0.582	0.39
62_A	66_Q	0.581	0.39
314_A	445_Y	0.581	0.39
135_V	170_T	0.579	0.39
140_N	174_A	0.579	0.39
34_V	42_L	0.579	0.39
145_F	389_R	0.579	0.39
193_N	448_S	0.578	0.39
126_V	194_K	0.577	0.39
232_D	402_K	0.576	0.39
225_A	240_L	0.575	0.39
284_A	333_K	0.574	0.39
29_D	58_A	0.574	0.39
276_I	296_D	0.573	0.38
93_R	96_I	0.573	0.38
72_I	84_Q	0.572	0.38
143_L	149_Y	0.570	0.38
217_I	335_G	0.570	0.38
66_Q	212_N	0.569	0.38
264_V	293_A	0.569	0.38
298_V	338_I	0.568	0.38
61_I	164_T	0.568	0.38
397_M	412_K	0.568	0.38
137_I	158_T	0.567	0.38
222_I	360_A	0.566	0.38
86_D	118_Y	0.566	0.38
266_K	269_E	0.564	0.38
35_E	337_T	0.562	0.37
147_S	264_V	0.561	0.37
252_T	282_A	0.560	0.37
11_L	16_V	0.560	0.37
62_A	300_V	0.559	0.37
48_S	54_V	0.559	0.37
260_V	444_G	0.558	0.37
407_Q	412_K	0.558	0.37
30_V	189_V	0.558	0.37
102_L	165_A	0.557	0.37
366_L	425_K	0.557	0.37
139_T	142_D	0.557	0.37
316_V	461_I	0.556	0.37
381_Q	473_P	0.556	0.37
324_I	328_A	0.556	0.37
145_F	179_Q	0.555	0.37
236_R	420_G	0.555	0.37
115_M	174_A	0.554	0.37
37_T	40_L	0.553	0.37
111_A	207_V	0.553	0.37
38_K	333_K	0.552	0.36
46_V	286_A	0.551	0.36
34_V	336_K	0.551	0.36
210_F	373_S	0.550	0.36
394_V	464_T	0.550	0.36
69_L	275_N	0.549	0.36
10_G	462_R	0.549	0.36
34_V	300_V	0.548	0.36
478_I	481_E	0.548	0.36
242_E	265_T	0.547	0.36
46_V	361_V	0.547	0.36
175_E	219_G	0.545	0.36
172_D	175_E	0.545	0.36
173_E	227_V	0.545	0.36
278_A	297_V	0.544	0.36
250_I	263_T	0.544	0.36
109_F	117_K	0.543	0.36
222_I	275_N	0.543	0.36
387_V	421_R	0.543	0.36
281_V	330_E	0.542	0.35
19_V	461_I	0.542	0.35
18_L	76_M	0.542	0.35
159_K	162_L	0.541	0.35
306_S	442_G	0.541	0.35
75_N	444_G	0.540	0.35
439_L	443_M	0.540	0.35
55_T	63_M	0.540	0.35
269_E	450_D	0.540	0.35
254_H	444_G	0.539	0.35
140_N	198_L	0.539	0.35
76_M	399_K	0.538	0.35
281_V	329_T	0.538	0.35
281_V	377_T	0.538	0.35
71_I	274_L	0.537	0.35
377_T	430_E	0.537	0.35
86_D	125_I	0.537	0.35
455_R	458_A	0.537	0.35
92_E	215_K	0.536	0.35
262_N	270_T	0.535	0.35
291_I	337_T	0.534	0.35
190_D	196_K	0.534	0.35
69_L	224_G	0.534	0.35
76_M	84_Q	0.533	0.35
27_P	444_G	0.533	0.35
59_M	62_A	0.532	0.35
86_D	90_R	0.532	0.35
216_D	220_R	0.532	0.35
28_R	410_N	0.532	0.35
69_L	222_I	0.532	0.35
450_D	458_A	0.532	0.35
123_V	210_F	0.530	0.34
231_G	235_T	0.530	0.34
179_Q	183_I	0.530	0.34
65_R	458_A	0.530	0.34
304_P	311_R	0.529	0.34
439_L	462_R	0.529	0.34
49_A	138_I	0.529	0.34
206_K	215_K	0.529	0.34
169_T	186_L	0.529	0.34
267_I	449_K	0.528	0.34
65_R	373_S	0.527	0.34
38_K	334_H	0.527	0.34
171_L	208_I	0.527	0.34
118_Y	140_N	0.527	0.34
86_D	123_V	0.527	0.34
153_I	385_F	0.527	0.34
359_H	459_Q	0.526	0.34
261_L	264_V	0.526	0.34
52_D	73_H	0.525	0.34
322_T	381_Q	0.524	0.34
367_L	423_P	0.523	0.34
271_Y	274_L	0.523	0.34
63_M	70_G	0.522	0.34
71_I	277_I	0.522	0.34
30_V	260_V	0.522	0.34
285_E	289_A	0.522	0.34
442_G	446_C	0.521	0.34
11_L	210_F	0.520	0.33
107_Q	150_S	0.519	0.33
59_M	425_K	0.518	0.33
155_D	180_K	0.517	0.33
158_T	184_E	0.516	0.33
448_S	454_L	0.516	0.33
214_S	217_I	0.516	0.33
63_M	66_Q	0.515	0.33
229_V	259_G	0.515	0.33
224_G	249_V	0.514	0.33
373_S	410_N	0.514	0.33
57_S	464_T	0.514	0.33
269_E	292_E	0.514	0.33
133_K	193_N	0.514	0.33
463_M	471_S	0.513	0.33
329_T	459_Q	0.513	0.33
314_A	467_G	0.512	0.33
58_A	457_E	0.512	0.33
8_K	322_T	0.512	0.33
299_K	311_R	0.511	0.33
69_L	337_T	0.511	0.33
30_V	47_I	0.511	0.33
35_E	159_K	0.510	0.33
355_A	477_Q	0.510	0.33
158_T	162_L	0.510	0.33
138_I	281_V	0.509	0.32
28_R	446_C	0.509	0.32
172_D	176_K	0.509	0.32
388_Y	392_G	0.509	0.32
175_E	204_I	0.508	0.32
96_I	187_P	0.508	0.32
75_N	405_Y	0.507	0.32
143_L	418_I	0.506	0.32
132_Q	351_T	0.506	0.32
33_S	132_Q	0.506	0.32
433_Y	441_S	0.506	0.32
112_E	123_V	0.506	0.32
88_V	246_D	0.505	0.32
148_D	278_A	0.505	0.32
288_R	329_T	0.505	0.32
414_V	444_G	0.504	0.32
78_I	82_A	0.504	0.32
182_K	268_R	0.504	0.32
38_K	335_G	0.504	0.32
151_M	156_V	0.503	0.32
449_K	457_E	0.503	0.32
59_M	214_S	0.503	0.32
431_T	435_L	0.503	0.32
38_K	360_A	0.502	0.32
405_Y	420_G	0.502	0.32
165_A	168_G	0.502	0.32
28_R	259_G	0.501	0.32
189_V	196_K	0.501	0.32
37_T	360_A	0.500	0.32
30_V	448_S	0.500	0.32
237_V	266_K	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3usbA	4	0.8914	100	0.433	Contact Map
2cu0A	4	0.7234	100	0.465	Contact Map
4af0A	3	0.7152	100	0.472	Contact Map
1vrdA	3	0.6578	100	0.473	Contact Map
1jcnA	6	0.7766	100	0.492	Contact Map
1zfjA	4	0.9734	100	0.499	Contact Map
1me8A	3	0.6988	100	0.531	Contact Map
4fxsA	3	0.9529	100	0.555	Contact Map
5ahnA	3	0.6086	100	0.558	Contact Map
4zqmA	3	0.666	100	0.629	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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