GREMLIN Database
RS21 - 30S ribosomal protein S21
UniProt: P21478 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 57 (55)
Sequences: 328 (106)
Seq/√Len: 14.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_E35_R4.4351.00
33_R36_E3.2440.98
43_V47_K2.7300.96
12_L24_S2.1370.85
5_V23_V1.8940.77
17_R50_E1.8670.76
20_K25_K1.8100.74
49_S53_R1.6800.68
34_K37_F1.5750.63
17_R25_K1.5600.62
39_E47_K1.5600.62
13_E22_S1.5510.62
42_S46_K1.3900.53
29_L32_A1.3700.52
48_K52_A1.3680.52
34_K47_K1.3610.51
23_V28_T1.3060.48
12_L50_E1.2470.45
35_R54_K1.1950.42
2_S22_S1.1570.40
6_V45_R1.1300.39
45_R48_K1.1060.38
34_K54_K1.0920.37
22_S25_K1.0680.36
4_T26_T1.0660.36
37_F42_S1.0330.34
38_Y43_V1.0280.34
44_K53_R1.0270.34
6_V23_V1.0040.33
5_V49_S0.9690.31
4_T28_T0.9530.30
39_E55_R0.9520.30
20_K54_K0.9290.29
7_R11_S0.8580.26
30_Q33_R0.8490.26
32_A55_R0.8410.25
20_K29_L0.8310.25
52_A55_R0.8260.25
21_R42_S0.8040.24
14_D33_R0.7750.23
22_S26_T0.7590.22
7_R14_D0.7570.22
26_T30_Q0.7560.22
4_T23_V0.7530.22
25_K51_A0.7460.22
48_K51_A0.7410.21
9_N13_E0.7350.21
33_R53_R0.7340.21
25_K52_A0.7270.21
3_K28_T0.6900.20
23_V36_E0.6850.19
22_S45_R0.6790.19
10_E18_R0.6630.19
24_S35_R0.6610.19
31_E34_K0.6600.19
7_R10_E0.6600.19
9_N21_R0.6530.18
11_S28_T0.6500.18
9_N49_S0.6480.18
11_S14_D0.6360.18
5_V33_R0.6340.18
2_S52_A0.6310.18
3_K7_R0.6290.18
27_G51_A0.6050.17
4_T24_S0.5980.17
24_S50_E0.5850.16
28_T34_K0.5840.16
17_R46_K0.5810.16
40_K46_K0.5780.16
18_R49_S0.5650.16
6_V25_K0.5590.15
8_K25_K0.5580.15
14_D24_S0.5530.15
24_S32_A0.5510.15
2_S44_K0.5480.15
8_K21_R0.5460.15
6_V30_Q0.5380.15
20_K52_A0.5350.15
14_D28_T0.5310.15
13_E38_Y0.5150.14
4_T8_K0.5070.14
44_K47_K0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bbnU 1 0.9298 99.8 0.219 Contact Map
4kiyU 1 0.8947 99.8 0.245 Contact Map
4tp8U 1 0.8947 99.7 0.302 Contact Map
5aj3U 1 0.9825 99.7 0.306 Contact Map
2qpvA 2 0.4386 7.1 0.906 Contact Map
1w3iA 3 0.5439 4.7 0.913 Contact Map
4lurA 1 0.5965 4.4 0.915 Contact Map
2y4tA 1 0.5965 4.1 0.916 Contact Map
2ia0A 2 0.4912 3.2 0.92 Contact Map
4ykeA 2 0 3 0.921 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0039 seconds.