GREMLIN Database
RS20 - 30S ribosomal protein S20
UniProt: P21477 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 88 (86)
Sequences: 2204 (1137)
Seq/√Len: 122.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
35_V83_V3.2531.00
43_E46_K3.0931.00
2_P11_T2.6971.00
59_D76_K2.6921.00
14_N18_R2.6561.00
33_K37_A2.3301.00
8_I12_K2.0051.00
71_T75_Y1.9601.00
27_A57_R1.9041.00
28_M67_V1.8681.00
44_A48_K1.8391.00
36_E82_K1.7931.00
62_V72_A1.6991.00
26_S30_T1.6861.00
51_L55_A1.6801.00
18_R22_A1.6111.00
15_N18_R1.5491.00
46_K50_A1.5031.00
67_V71_T1.4571.00
45_D49_T1.4551.00
56_K60_K1.4151.00
24_I66_L1.4031.00
45_D48_K1.3951.00
58_I72_A1.3941.00
48_K52_T1.3631.00
51_L83_V1.3231.00
35_V39_V1.2691.00
15_N19_V1.2420.99
20_H24_I1.2370.99
53_E57_R1.2360.99
35_V51_L1.2200.99
74_R78_R1.2070.99
49_T52_T1.2010.99
27_A31_A1.1980.99
46_K49_T1.1970.99
36_E40_A1.1780.99
51_L80_A1.1720.99
82_K85_G1.1680.99
55_A80_A1.1600.99
81_K85_G1.1340.99
39_V82_K1.1280.99
4_I8_I1.1110.99
62_V67_V1.1050.99
13_T17_R1.1000.99
10_R14_N1.0850.99
10_R13_T1.0450.98
38_S50_A1.0010.98
16_E20_H0.9980.98
30_T34_Q0.9960.97
49_T53_E0.9600.97
60_K63_K0.9410.96
80_A84_N0.9300.96
28_M61_A0.9230.96
11_T15_N0.9020.95
35_V54_A0.8940.95
31_A57_R0.8860.95
32_I58_I0.8860.95
11_T14_N0.8840.95
56_K63_K0.8710.95
40_A82_K0.8670.94
19_V23_T0.8490.94
81_K84_N0.8390.93
70_N76_K0.8220.93
35_V79_L0.8210.93
50_A54_A0.8210.93
19_V22_A0.8060.92
67_V72_A0.7710.90
44_A86_L0.7700.90
52_T55_A0.7630.90
73_A77_S0.7630.90
24_I61_A0.7620.90
52_T56_K0.7580.89
39_V83_V0.7540.89
23_T27_A0.7460.89
8_I11_T0.7380.88
7_A14_N0.7330.88
34_Q46_K0.7170.87
38_S46_K0.7000.85
34_Q50_A0.6830.84
7_A71_T0.6670.82
21_N24_I0.6580.82
31_A54_A0.6520.81
4_I7_A0.6450.80
26_S29_R0.6410.80
12_K16_E0.6400.80
34_Q53_E0.6390.80
36_E78_R0.6370.79
62_V76_K0.6310.79
6_S61_A0.6260.78
36_E75_Y0.6230.78
27_A30_T0.6230.78
58_I79_L0.6230.78
34_Q37_A0.6170.77
35_V50_A0.6170.77
29_R75_Y0.6090.76
13_T16_E0.6050.76
14_N17_R0.6050.76
32_I36_E0.6010.75
4_I11_T0.6010.75
43_E47_A0.6000.75
74_R79_L0.5940.75
75_Y79_L0.5920.74
4_I12_K0.5920.74
38_S47_A0.5840.73
47_A83_V0.5840.73
37_A41_N0.5780.73
57_R61_A0.5760.72
55_A59_D0.5750.72
7_A13_T0.5640.71
53_E56_K0.5610.70
52_T77_S0.5600.70
5_K12_K0.5580.70
26_S31_A0.5520.69
39_V44_A0.5480.69
47_A51_L0.5460.68
73_A76_K0.5460.68
23_T26_S0.5390.67
38_S43_E0.5380.67
55_A76_K0.5380.67
5_K84_N0.5340.67
28_M66_L0.5310.66
7_A10_R0.5250.65
14_N74_R0.5150.64
5_K8_I0.5150.64
31_A50_A0.5090.63
4_I13_T0.5060.62
31_A53_E0.5050.62
24_I64_T0.5050.62
59_D62_V0.5000.62
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rb5T 1 0.9773 100 0.055 Contact Map
3bbnT 1 1 100 0.06 Contact Map
4tp8T 1 0.9659 100 0.11 Contact Map
3osrA 1 0.4659 15.6 0.909 Contact Map
4bujB 1 0.7386 6.6 0.923 Contact Map
4qinA 2 0.9091 6.5 0.924 Contact Map
4lcbA 1 0 5 0.928 Contact Map
2ra1A 1 0.8523 4.6 0.929 Contact Map
3lofA 2 0.875 3.8 0.932 Contact Map
1vykA 1 0.6932 3.2 0.934 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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