GREMLIN Database
RS16 - 30S ribosomal protein S16
UniProt: P21474 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 90 (79)
Sequences: 2547 (1181)
Seq/√Len: 132.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
58_K62_T3.2891.00
55_L58_K3.0641.00
37_V56_A2.4641.00
41_N44_A2.1841.00
5_I22_V2.1371.00
35_E55_L1.9431.00
8_K36_T1.8721.00
44_A48_E1.7811.00
66_P74_F1.7761.00
22_V37_V1.7441.00
23_A27_S1.6171.00
39_T50_K1.6051.00
53_E57_L1.5721.00
23_A33_F1.5041.00
4_K67_S1.4961.00
12_A15_S1.4911.00
4_K25_S1.3601.00
60_L66_P1.3281.00
3_V34_I1.3261.00
19_R36_T1.3111.00
68_D71_R1.2901.00
10_M19_R1.2681.00
57_L78_G1.2521.00
57_L61_Q1.2461.00
74_F79_I1.2351.00
72_N76_S1.2321.00
22_V34_I1.2261.00
20_I51_I1.2251.00
3_V22_V1.2241.00
15_S43_V1.2071.00
69_T72_N1.2071.00
51_I56_A1.2051.00
33_F36_T1.2031.00
52_D55_L1.1990.99
17_F39_T1.1950.99
27_S32_R1.1880.99
56_A74_F1.1790.99
58_K61_Q1.1590.99
16_P43_V1.1430.99
8_K33_F1.1300.99
41_N48_E1.1190.99
47_A50_K1.0970.99
75_S80_M1.0960.99
28_P33_F1.0690.99
5_I64_A1.0690.99
55_L62_T1.0580.99
36_T39_T1.0150.98
72_N75_S1.0100.98
57_L79_I1.0050.98
71_R80_M0.9930.98
10_M36_T0.9770.98
9_R16_P0.9490.97
5_I70_V0.9240.97
57_L80_M0.9140.97
20_I70_V0.9080.97
7_L67_S0.9040.96
53_E77_Q0.8860.96
71_R75_S0.8850.96
17_F43_V0.8830.96
25_S67_S0.8570.95
24_D34_I0.8420.95
40_Y69_T0.8070.93
53_E79_I0.7960.93
7_L73_L0.7950.93
2_A65_K0.7940.93
69_T76_S0.7880.93
51_I73_L0.7790.92
17_F41_N0.7720.92
3_V24_D0.7720.92
44_A47_A0.7610.91
7_L20_I0.7570.91
57_L60_L0.7540.91
59_W62_T0.7400.90
28_P32_R0.7330.90
35_E59_W0.7290.89
28_P31_G0.7220.89
56_A66_P0.7140.88
51_I74_F0.7040.88
8_K30_D0.7010.88
10_M17_F0.6880.87
43_V47_A0.6840.86
74_F78_G0.6840.86
66_P70_V0.6770.86
60_L74_F0.6580.84
19_R40_Y0.6540.84
43_V48_E0.6530.84
4_K65_K0.6470.83
20_I73_L0.6420.83
52_D56_A0.6370.82
18_Y76_S0.6300.81
48_E76_S0.6300.81
70_V73_L0.6270.81
44_A73_L0.6140.80
39_T48_E0.6100.79
23_A32_R0.6040.79
23_A28_P0.6010.78
27_S33_F0.6000.78
53_E78_G0.5780.76
60_L65_K0.5770.75
53_E80_M0.5730.75
49_V73_L0.5690.74
53_E74_F0.5590.73
35_E58_K0.5540.73
20_I60_L0.5510.72
3_V26_R0.5500.72
60_L79_I0.5460.71
75_S79_I0.5390.70
54_E57_L0.5380.70
22_V64_A0.5360.70
35_E64_A0.5320.69
61_Q65_K0.5260.69
21_V33_F0.5250.68
19_R72_N0.5220.68
70_V74_F0.5120.67
54_E78_G0.5090.66
51_I79_I0.5060.66
22_V59_W0.5040.65
8_K19_R0.5000.65
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bn0A 1 0.9111 100 0.073 Contact Map
5aj3P 1 1 100 0.088 Contact Map
4juwP 1 0.9111 100 0.097 Contact Map
3bbnP 1 0.8889 100 0.104 Contact Map
4tp8P 1 0.8889 100 0.119 Contact Map
3c0kA 2 0.9444 30.1 0.915 Contact Map
3ks9A 2 0.5444 18.9 0.922 Contact Map
4ms4B 1 0.6333 15.3 0.926 Contact Map
4ms4A 1 0.6889 13.7 0.927 Contact Map
3sm9A 2 0.5444 9.7 0.932 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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