GREMLIN Database
RS10 - 30S ribosomal protein S10
UniProt: P21471 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 102 (99)
Sequences: 799 (353)
Seq/√Len: 35.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
50_T64_Q5.1841.00
53_R61_S4.6101.00
7_R75_D4.3131.00
32_S83_T4.3021.00
47_S69_T3.7641.00
50_T62_R3.1891.00
54_A58_Y2.9741.00
52_L55_V2.4391.00
12_A18_L2.2420.99
54_A57_K2.0720.99
46_K68_R1.8440.97
18_L22_A1.7070.96
12_A91_D1.6340.94
75_D90_L1.5820.93
52_L60_D1.5680.93
57_K60_D1.5470.92
52_L56_H1.5390.92
53_R65_F1.5300.92
61_S65_F1.4700.90
23_E27_E1.4520.90
28_T31_R1.4130.88
5_K18_L1.4070.88
55_V58_Y1.3790.87
93_P98_I1.3720.87
11_K99_E1.3520.86
27_E60_D1.3310.85
35_S78_N1.3120.84
5_K37_S1.2290.80
56_H62_R1.2170.80
48_V64_Q1.1600.76
47_S67_M1.1530.76
22_A37_S1.1400.75
28_T86_A1.1200.74
15_H19_D1.1070.73
24_K91_D1.0760.71
52_L57_K1.0690.70
47_S50_T1.0160.66
19_D72_R1.0070.65
16_R19_D0.9860.64
47_S64_Q0.9840.64
74_I85_D0.9810.63
10_L18_L0.9780.63
8_I30_K0.9730.63
19_D41_P0.9540.61
22_A26_V0.9320.59
45_E71_K0.9290.59
52_L62_R0.9230.59
63_E81_P0.9050.57
29_A73_L0.8960.56
5_K52_L0.8900.56
52_L69_T0.8680.54
56_H68_R0.8520.52
50_T56_H0.8510.52
71_K74_I0.8430.52
14_D19_D0.8370.51
26_V74_I0.8340.51
29_A34_A0.8310.51
33_G83_T0.8270.50
37_S74_I0.8240.50
28_T88_M0.8190.50
37_S93_P0.8170.49
40_I77_V0.8120.49
6_I9_R0.8080.49
17_I35_S0.8020.48
29_A76_I0.7930.47
40_I73_L0.7860.47
24_K89_R0.7790.46
60_D64_Q0.7660.45
48_V51_I0.7600.45
66_E78_N0.7570.44
88_M97_D0.7530.44
18_L21_S0.7530.44
37_S77_V0.7500.44
17_I21_S0.7480.44
47_S71_K0.7420.43
14_D41_P0.7390.43
53_R63_E0.7350.42
6_I36_V0.7340.42
3_K58_Y0.7330.42
27_E31_R0.7330.42
12_A67_M0.7020.40
49_Y69_T0.6920.39
30_K56_H0.6880.39
37_S67_M0.6850.38
28_T90_L0.6830.38
27_E79_P0.6700.37
54_A91_D0.6690.37
9_R45_E0.6660.37
35_S77_V0.6650.37
42_L73_L0.6650.37
80_T85_D0.6620.36
25_I74_I0.6610.36
45_E58_Y0.6600.36
55_V88_M0.6590.36
69_T94_S0.6590.36
41_P72_R0.6570.36
14_D40_I0.6550.36
42_L93_P0.6520.36
13_Y100_I0.6430.35
17_I101_K0.6400.35
49_Y58_Y0.6390.35
24_K94_S0.6360.34
82_Q86_A0.6290.34
98_I101_K0.6220.33
34_A83_T0.6190.33
29_A74_I0.6160.33
51_I55_V0.6070.32
47_S51_I0.6070.32
53_R101_K0.6010.32
40_I89_R0.6010.32
32_S80_T0.5920.31
53_R56_H0.5920.31
48_V68_R0.5900.31
44_T93_P0.5830.30
5_K75_D0.5820.30
6_I54_A0.5800.30
41_P85_D0.5790.30
30_K35_S0.5770.30
27_E34_A0.5750.30
3_K9_R0.5650.29
8_I68_R0.5600.29
13_Y45_E0.5600.29
42_L99_E0.5590.29
73_L92_L0.5590.29
88_M98_I0.5590.29
24_K82_Q0.5490.28
78_N100_I0.5480.28
8_I83_T0.5480.28
24_K60_D0.5460.28
44_T70_H0.5440.28
21_S87_L0.5420.27
74_I97_D0.5370.27
32_S87_L0.5330.27
12_A41_P0.5330.27
22_A73_L0.5290.27
25_I83_T0.5260.26
45_E48_V0.5240.26
20_Q30_K0.5170.26
21_S73_L0.5150.26
15_H63_E0.5110.25
25_I28_T0.5100.25
31_R49_Y0.5090.25
29_A36_V0.5070.25
81_P99_E0.5050.25
9_R42_L0.5030.25
17_I77_V0.5030.25
18_L82_Q0.5020.25
25_I41_P0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bbnJ 1 0.9706 100 0.23 Contact Map
3w1yC 1 0.8725 100 0.242 Contact Map
3zeyQ 1 0.9902 100 0.266 Contact Map
4rb5J 1 0.951 100 0.268 Contact Map
3j20L 1 0.9706 100 0.269 Contact Map
4w23U 1 0.9804 100 0.272 Contact Map
3j7aN 1 0.9216 100 0.273 Contact Map
4bpeJ 1 0.9902 100 0.276 Contact Map
3j60U 1 0.9902 100 0.276 Contact Map
4ujpV 1 0.9902 100 0.278 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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