GREMLIN Database
RS9 - 30S ribosomal protein S9
UniProt: P21470 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 130 (126)
Sequences: 2850 (1237)
Seq/√Len: 110.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
118_L124_A4.6111.00
65_V79_I2.9921.00
84_A104_L2.8781.00
19_V82_G2.7591.00
88_L104_L2.5061.00
111_K120_G2.4321.00
118_L125_P2.4171.00
119_K125_P2.2531.00
120_G123_R2.1821.00
61_Y90_A2.0841.00
36_S45_I2.0781.00
50_Q103_L2.0141.00
96_T100_R1.9781.00
7_Y20_R1.9731.00
42_A45_I1.9421.00
5_Q20_R1.8581.00
14_S110_M1.8261.00
26_G62_D1.8191.00
95_R99_K1.8141.00
50_Q80_R1.8111.00
11_R85_R1.7801.00
27_R62_D1.7471.00
52_L63_V1.7291.00
35_I45_I1.7271.00
88_L95_R1.6861.00
22_V64_L1.6691.00
27_R34_E1.6411.00
119_K123_R1.6371.00
53_T58_A1.6071.00
40_P45_I1.5471.00
5_Q22_V1.5361.00
54_L101_A1.5161.00
39_I79_I1.4501.00
55_T94_Y1.4431.00
24_G62_D1.4371.00
33_R37_E1.4301.00
67_V79_I1.3981.00
57_T94_Y1.3951.00
35_I48_I1.3711.00
47_D50_Q1.3591.00
25_E62_D1.3210.99
34_E37_E1.2620.99
73_S77_G1.2580.99
77_G80_R1.2520.99
111_K114_K1.1890.99
57_T60_T1.1800.99
8_G86_A1.1670.99
57_T61_Y1.1400.99
23_P60_T1.1170.98
119_K124_A1.1120.98
11_R16_V1.0950.98
29_V64_L1.0700.98
112_E115_K1.0660.98
82_G106_R1.0550.98
49_K58_A1.0530.97
44_L72_L1.0380.97
12_R77_G1.0320.97
21_L86_A1.0150.97
120_G125_P1.0150.97
44_L73_S1.0070.97
55_T98_L1.0050.97
80_R103_L0.9830.96
47_D77_G0.9710.96
11_R110_M0.9530.95
22_V62_D0.9480.95
70_G74_G0.9470.95
74_G77_G0.9250.95
11_R81_H0.9220.95
48_I51_P0.9210.95
40_P72_L0.9140.94
120_G124_A0.9110.94
9_T82_G0.9030.94
32_N66_N0.8970.94
41_S72_L0.8900.94
46_E50_Q0.8800.93
21_L63_V0.8760.93
116_Y127_F0.8740.93
6_Y90_A0.8720.93
49_K52_L0.8700.93
90_A94_Y0.8670.93
84_A88_L0.8650.93
18_R66_N0.8590.92
15_S74_G0.8460.92
47_D76_A0.8370.91
20_R66_N0.8280.91
91_D94_Y0.8250.91
99_K105_T0.8230.91
114_K120_G0.8190.90
54_L103_L0.8170.90
25_E46_E0.8090.90
114_K119_K0.8000.89
88_L94_Y0.7940.89
97_T101_A0.7910.89
105_T108_A0.7890.89
7_Y66_N0.7890.89
42_A46_E0.7860.88
15_S70_G0.7800.88
48_I76_A0.7780.88
57_T91_D0.7780.88
111_K123_R0.7760.88
52_L59_G0.7730.88
33_R40_P0.7680.87
8_G89_E0.7670.87
36_S49_K0.7640.87
43_A46_E0.7630.87
17_A67_V0.7580.87
95_R104_L0.7550.86
8_G19_V0.7540.86
81_H106_R0.7530.86
6_Y88_L0.7520.86
6_Y21_L0.7460.86
28_I35_I0.7460.86
29_V34_E0.7420.85
54_L97_T0.7350.85
7_Y18_R0.7240.84
29_V32_N0.7230.84
88_L99_K0.7150.83
49_K53_T0.7130.83
21_L61_Y0.7090.83
116_Y125_P0.7040.82
123_R127_F0.7030.82
18_R67_V0.7030.82
47_D103_L0.6960.82
22_V90_A0.6870.81
41_S44_L0.6840.80
35_I40_P0.6710.79
10_G16_V0.6520.77
29_V66_N0.6480.77
19_V123_R0.6440.76
30_V39_I0.6430.76
52_L57_T0.6430.76
46_E49_K0.6420.76
85_R106_R0.6390.76
55_T58_A0.6380.76
28_I48_I0.6340.75
111_K119_K0.6330.75
92_P97_T0.6300.75
46_E53_T0.6220.74
97_T100_R0.6140.73
39_I48_I0.6130.73
10_G17_A0.6120.73
45_I48_I0.6050.72
119_K127_F0.5980.71
114_K117_G0.5940.70
39_I113_R0.5910.70
52_L83_I0.5870.70
52_L61_Y0.5850.69
47_D80_R0.5830.69
114_K118_L0.5810.69
122_R130_R0.5800.69
8_G21_L0.5750.68
119_K126_Q0.5710.67
44_L47_D0.5710.67
15_S78_A0.5640.66
39_I73_S0.5640.66
5_Q64_L0.5630.66
10_G81_H0.5610.66
9_T98_L0.5600.66
90_A96_T0.5540.65
40_P44_L0.5530.65
81_H85_R0.5500.65
17_A79_I0.5500.65
38_H113_R0.5450.64
40_P79_I0.5440.64
20_R64_L0.5430.64
30_V34_E0.5390.63
67_V72_L0.5370.63
20_R111_K0.5350.62
26_G31_N0.5340.62
21_L83_I0.5340.62
114_K121_A0.5320.62
16_V116_Y0.5290.62
92_P99_K0.5280.61
118_L123_R0.5260.61
33_R110_M0.5250.61
10_G78_A0.5250.61
111_K116_Y0.5240.61
119_K128_S0.5230.61
83_I98_L0.5220.61
33_R74_G0.5210.60
28_I49_K0.5200.60
99_K104_L0.5160.60
60_T68_H0.5110.59
32_N37_E0.5100.59
8_G87_L0.5100.59
20_R74_G0.5090.59
15_S110_M0.5070.58
16_V68_H0.5050.58
50_Q127_F0.5000.57
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rb5I 1 0.9769 100 0.037 Contact Map
3bbnI 1 0.9692 100 0.041 Contact Map
4tp8I 1 0.9769 100 0.042 Contact Map
5aj3I 1 0.9923 100 0.054 Contact Map
4bpeI 1 0.9923 100 0.071 Contact Map
3j60Q 1 0.8692 100 0.073 Contact Map
3j7aM 1 0.9615 100 0.075 Contact Map
4ujpR 1 0.9846 100 0.078 Contact Map
4w23Q 1 0.9846 100 0.079 Contact Map
3zeyK 1 0.9923 100 0.086 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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