GREMLIN Database
RS5 - 30S ribosomal protein S5
UniProt: P21467 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 166 (155)
Sequences: 2374 (1053)
Seq/√Len: 84.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
12_E42_K3.6861.00
142_Q146_E3.2011.00
41_D45_H2.9171.00
100_S124_L2.8391.00
37_V63_A2.8341.00
87_G142_Q2.7091.00
24_V31_F2.6161.00
148_K156_L2.5481.00
79_T122_D2.3961.00
142_Q145_S2.1551.00
12_E117_L2.1421.00
48_F137_I2.1371.00
115_L120_V2.0161.00
58_E61_R2.0071.00
34_A50_T1.9921.00
24_V29_R1.9561.00
48_F141_L1.9201.00
76_M120_V1.9031.00
81_I96_L1.8741.00
81_I123_I1.8621.00
81_I147_L1.8441.00
84_E98_P1.8401.00
48_F138_R1.7991.00
101_E122_D1.7971.00
45_H71_L1.7891.00
64_V68_K1.7381.00
16_V137_I1.7361.00
19_N34_A1.7141.00
115_L123_I1.6891.00
11_L45_H1.6811.00
103_T124_L1.6471.00
33_F56_V1.6201.00
50_T134_I1.6061.00
111_V125_S1.5931.00
79_T121_A1.5821.00
25_V30_R1.5661.00
86_I93_N1.5661.00
149_R152_D1.5431.00
45_H73_E1.5191.00
9_L45_H1.5100.99
84_E97_K1.4770.99
85_I146_E1.4710.99
35_A59_A1.4570.99
66_D70_N1.3700.99
95_L128_L1.3660.99
111_V115_L1.3460.99
82_P147_L1.3380.99
20_R31_F1.3350.99
127_S136_M1.3290.99
99_A103_T1.3160.99
88_R93_N1.3050.99
15_L18_V1.2860.98
92_G127_S1.2830.98
72_I145_S1.2780.98
21_V32_R1.2730.98
61_R65_E1.2720.98
85_I96_L1.2680.98
43_N76_M1.2380.98
76_M79_T1.2220.98
22_A31_F1.1930.97
49_G66_D1.1890.97
13_E64_V1.1780.97
15_L37_V1.1600.97
86_I95_L1.1490.97
72_I141_L1.1440.97
96_L143_G1.1300.96
152_D155_K1.1250.96
150_A161_V1.1140.96
80_T122_D1.1080.96
134_I138_R1.0680.95
15_L35_A1.0640.95
38_V114_V1.0600.95
11_L71_L1.0560.95
17_T34_A1.0380.94
127_S131_N1.0080.93
87_G92_G0.9700.92
32_R54_Q0.9610.91
114_V137_I0.9550.91
74_V118_A0.9510.91
85_I147_L0.9420.90
77_V150_A0.9240.90
96_L140_T0.9190.89
50_T132_T0.9140.89
30_R54_Q0.9080.89
89_F138_R0.9050.89
156_L159_K0.9000.88
8_K11_L0.8930.88
46_V141_L0.8930.88
77_V80_T0.8840.87
75_P82_P0.8800.87
50_T63_A0.8740.87
11_L39_V0.8700.87
110_P137_I0.8670.86
18_V57_P0.8640.86
152_D156_L0.8610.86
38_V117_L0.8540.86
46_V118_A0.8510.85
82_P150_A0.8480.85
56_V60_I0.8260.84
151_E155_K0.8210.83
114_V140_T0.8190.83
32_R124_L0.8170.83
16_V38_V0.8170.83
92_G130_S0.8150.83
92_G128_L0.8150.83
11_L43_N0.8120.83
110_P136_M0.8080.82
14_R133_P0.8040.82
105_V115_L0.8010.82
15_L60_I0.8010.82
38_V137_I0.8010.82
18_V55_E0.8000.82
103_T106_I0.7960.81
135_N138_R0.7920.81
44_G76_M0.7910.81
35_A56_V0.7910.81
37_V64_V0.7870.81
52_K62_K0.7870.81
76_M122_D0.7860.81
140_T144_L0.7790.80
154_A161_V0.7750.80
89_F142_Q0.7710.79
39_V67_A0.7690.79
51_G66_D0.7670.79
46_V72_I0.7620.78
18_V56_V0.7620.78
22_A30_R0.7610.78
107_A126_K0.7600.78
94_I139_A0.7550.78
96_L125_S0.7470.77
92_G131_N0.7330.76
18_V35_A0.7320.76
14_R117_L0.7320.76
42_K116_E0.7260.75
28_G40_G0.7210.75
87_G139_A0.7180.74
110_P114_V0.7180.74
74_V120_V0.7160.74
36_L134_I0.7090.73
73_E76_M0.7070.73
29_R135_N0.7060.73
35_A60_I0.6980.72
92_G136_M0.6980.72
20_R27_G0.6960.72
49_G70_N0.6960.72
24_V27_G0.6890.71
9_L68_K0.6880.71
154_A159_K0.6860.71
42_K117_L0.6810.70
93_N129_G0.6790.70
104_G119_G0.6760.70
10_E18_V0.6750.70
106_I132_T0.6730.69
20_R33_F0.6690.69
107_A125_S0.6670.69
148_K152_D0.6670.69
53_A103_T0.6650.68
72_I75_P0.6630.68
79_T101_E0.6620.68
105_V137_I0.6600.68
51_G62_K0.6600.68
31_F34_A0.6590.68
78_G122_D0.6580.68
16_V130_S0.6580.68
28_G104_G0.6550.67
10_E43_N0.6520.67
76_M118_A0.6470.66
46_V73_E0.6420.66
17_T133_P0.6420.66
103_T108_G0.6390.65
154_A158_G0.6390.65
19_N134_I0.6330.65
42_K121_A0.6330.65
85_I143_G0.6270.64
91_A130_S0.6270.64
86_I146_E0.6200.63
107_A123_I0.6140.62
46_V114_V0.6090.62
32_R50_T0.6080.62
115_L125_S0.6070.61
22_A29_R0.6010.61
21_V51_G0.6000.61
9_L71_L0.5960.60
113_A116_E0.5870.59
88_R155_K0.5830.58
41_D71_L0.5800.58
115_L118_A0.5770.58
9_L43_N0.5750.57
16_V49_G0.5730.57
12_E71_L0.5730.57
120_V123_I0.5690.57
138_R145_S0.5680.56
93_N128_L0.5680.56
35_A48_F0.5680.56
12_E66_D0.5650.56
111_V136_M0.5610.55
50_T138_R0.5610.55
29_R65_E0.5600.55
22_A25_V0.5570.55
8_K158_G0.5560.55
51_G59_A0.5550.55
50_T58_E0.5550.55
55_E80_T0.5450.53
151_E158_G0.5420.53
19_N50_T0.5410.53
68_K147_L0.5410.53
73_E78_G0.5400.53
129_G156_L0.5400.53
44_G119_G0.5380.52
14_R113_A0.5380.52
114_V141_L0.5370.52
30_R56_V0.5350.52
52_K126_K0.5330.52
28_G102_G0.5310.52
94_I111_V0.5300.51
16_V48_F0.5280.51
15_L63_A0.5270.51
150_A154_A0.5250.51
17_T134_I0.5250.51
31_F54_Q0.5240.51
69_K132_T0.5240.51
59_A121_A0.5220.50
51_G63_A0.5210.50
71_L141_L0.5200.50
44_G115_L0.5180.50
53_A59_A0.5170.50
87_G94_I0.5170.50
116_E126_K0.5140.49
88_R142_Q0.5110.49
106_I124_L0.5080.48
106_I116_E0.5000.47
48_F89_F0.5000.47
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4kiyE 1 0.9036 100 0.038 Contact Map
4rb5E 1 0.8916 100 0.048 Contact Map
3bbnE 1 0.9458 100 0.055 Contact Map
5aj3E 1 1 100 0.062 Contact Map
4tp8E 1 0.9036 100 0.089 Contact Map
1pkpA 2 0.8735 100 0.115 Contact Map
3j20F 1 0.9217 100 0.119 Contact Map
4kzyC 1 1 100 0.16 Contact Map
3j80C 1 1 100 0.16 Contact Map
3zeyP 1 1 100 0.16 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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