GREMLIN Database
SP3E - DNA translocase SpoIIIE
UniProt: P21458 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 787 (705)
Sequences: 3393 (2331)
Seq/√Len: 87.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
532_V577_V5.6011.00
726_V758_M5.3721.00
728_L744_F5.1681.00
323_A688_K4.6941.00
482_T689_V4.5951.00
425_K429_E4.5241.00
431_K435_R4.4211.00
319_L428_L4.1441.00
481_I497_M4.0631.00
559_K571_E3.9321.00
577_V609_I3.7861.00
768_E774_E3.6241.00
324_D425_K3.5701.00
489_K492_E3.5031.00
732_M739_M3.4071.00
349_Q354_K3.3421.00
480_I612_I3.3211.00
24_G68_G3.2941.00
730_V775_V3.2211.00
325_P426_E3.2161.00
542_L572_L3.2051.00
28_I68_G3.1991.00
620_V647_T3.1701.00
538_R542_L3.1631.00
438_A441_L3.1301.00
340_N369_Y3.1121.00
551_I574_Y3.0651.00
39_G42_G3.0131.00
729_I735_A2.9991.00
382_I410_I2.9841.00
436_P441_L2.8841.00
424_L428_L2.8361.00
481_I578_I2.8171.00
31_S65_L2.8091.00
722_Y763_V2.8051.00
455_A460_M2.7501.00
724_E727_E2.7031.00
537_E603_M2.6991.00
550_N553_G2.6801.00
515_L575_I2.6801.00
447_N451_E2.6331.00
722_Y761_R2.6111.00
642_Q652_G2.5861.00
373_P382_I2.5841.00
579_V582_L2.5551.00
455_A665_F2.5531.00
690_V694_I2.5241.00
484_I493_V2.5191.00
156_F164_M2.4981.00
334_K338_Y2.4811.00
735_A755_I2.4801.00
722_Y726_V2.4641.00
725_A744_F2.4471.00
692_H696_Q2.3991.00
354_K374_D2.3971.00
502_M603_M2.3881.00
345_E357_V2.3881.00
755_I758_M2.3571.00
579_V613_I2.3541.00
727_E731_G2.3431.00
438_A488_A2.3411.00
463_L635_I2.3391.00
468_A471_S2.3301.00
41_V156_F2.3141.00
730_V777_L2.3101.00
728_L739_M2.3041.00
31_S68_G2.2831.00
492_E571_E2.2721.00
598_T626_V2.2141.00
549_R683_D2.2091.00
342_R345_E2.2021.00
346_R350_S2.1831.00
497_M578_I2.1591.00
729_I758_M2.1451.00
31_S61_L2.1401.00
380_S384_N2.1291.00
749_T756_D2.1261.00
476_C479_G2.1241.00
419_V660_R2.1221.00
439_K492_E2.1201.00
442_I612_I2.1031.00
489_K494_K2.0961.00
725_A758_M2.0811.00
304_M307_T2.0761.00
553_G683_D2.0661.00
684_D688_K2.0511.00
341_A360_V2.0491.00
723_D727_E2.0331.00
441_L488_A2.0011.00
476_C635_I1.9981.00
482_T681_L1.9531.00
769_G772_P1.9471.00
737_V755_I1.9391.00
512_P517_P1.9111.00
344_L389_L1.9111.00
491_H494_K1.9111.00
314_Y693_V1.9061.00
440_L484_I1.8701.00
725_A728_L1.8601.00
543_F607_A1.8441.00
484_I488_A1.8331.00
424_L681_L1.7941.00
691_D695_T1.7861.00
345_E356_K1.7831.00
488_A493_V1.7721.00
318_S692_H1.7721.00
315_E692_H1.7671.00
370_E407_K1.7651.00
687_E691_D1.7601.00
633_S668_V1.7451.00
502_M541_E1.7321.00
546_T554_Y1.7271.00
432_L454_L1.7261.00
444_L635_I1.7221.00
549_R686_V1.7101.00
635_I663_M1.7071.00
484_I576_V1.7001.00
758_M763_V1.6771.00
732_M743_R1.6721.00
725_A740_L1.6561.00
726_V763_V1.6491.00
389_L392_A1.6481.00
358_T409_A1.6481.00
344_L412_I1.6331.00
476_C480_I1.6301.00
338_Y342_R1.6191.00
302_P305_T1.6151.00
91_I172_G1.6071.00
582_L597_I1.6001.00
505_L637_F1.5961.00
319_L429_E1.5871.00
305_T308_E1.5781.00
441_L487_R1.5751.00
392_A408_S1.5561.00
688_K691_D1.5461.00
519_V528_A1.5301.00
582_L586_M1.5291.00
765_G776_L1.5231.00
559_K563_N1.5191.00
206_D210_F1.5171.00
730_V779_K1.5151.00
754_L757_A1.5141.00
548_T553_G1.5111.00
531_K705_M1.5091.00
375_V398_I1.5031.00
768_E771_K1.4931.00
21_E180_S1.4851.00
337_I341_A1.4780.99
347_T389_L1.4700.99
433_N486_M1.4560.99
210_F213_N1.4550.99
326_K423_S1.4540.99
532_V609_I1.4490.99
337_I362_L1.4460.99
439_K488_A1.4330.99
587_M602_Q1.4280.99
644_D647_T1.4250.99
757_A761_R1.4190.99
365_A677_Q1.4040.99
18_I21_E1.4040.99
29_A167_V1.3950.99
87_G101_V1.3910.99
600_L620_V1.3910.99
426_E446_R1.3830.99
94_S105_K1.3690.99
227_Q231_R1.3630.99
387_D402_A1.3620.99
525_A533_V1.3560.99
746_I749_T1.3530.99
556_D560_R1.3420.99
297_E301_A1.3390.99
302_P307_T1.3370.99
57_F61_L1.3360.99
423_S426_E1.3360.99
348_F371_V1.3310.99
488_A492_E1.3260.99
389_L398_I1.3190.99
191_P194_R1.3140.99
220_T223_P1.3130.99
24_G27_C1.3120.99
463_L612_I1.3110.99
758_M761_R1.3100.99
739_M743_R1.3060.99
203_F210_F1.3040.99
765_G769_G1.3000.99
734_T767_Y1.2990.99
195_F199_Q1.2940.99
207_M210_F1.2900.99
453_V676_V1.2840.99
726_V730_V1.2810.99
303_P306_F1.2810.99
346_R349_Q1.2790.98
34_A45_F1.2780.98
718_T761_R1.2750.98
340_N417_A1.2680.98
468_A638_S1.2670.98
498_I519_V1.2600.98
765_G768_E1.2590.98
298_T302_P1.2590.98
394_A412_I1.2590.98
477_V582_L1.2590.98
365_A676_V1.2580.98
224_S227_Q1.2480.98
28_I65_L1.2470.98
355_A677_Q1.2310.98
514_L517_P1.2280.98
101_V105_K1.2200.98
85_K89_Y1.2190.98
92_I96_L1.2130.98
98_L102_Q1.2110.98
365_A419_V1.2060.98
142_G145_G1.2050.98
749_T752_A1.2040.98
166_I170_L1.2040.98
438_A456_E1.2020.98
502_M544_S1.1940.98
270_E277_K1.1880.98
439_K574_Y1.1880.98
296_Q299_V1.1860.98
87_G94_S1.1860.98
651_M673_P1.1840.98
341_A357_V1.1840.98
432_L451_E1.1820.97
159_T163_I1.1730.97
510_G694_I1.1680.97
755_I767_Y1.1660.97
228_K232_K1.1620.97
428_L443_G1.1610.97
732_M744_F1.1600.97
718_T757_A1.1510.97
745_R754_L1.1510.97
421_M660_R1.1500.97
337_I360_V1.1480.97
206_D209_S1.1420.97
355_A371_V1.1400.97
633_S667_P1.1400.97
181_L184_T1.1360.97
299_V302_P1.1350.97
582_L613_I1.1320.97
217_S221_K1.1310.97
213_N217_S1.1300.97
96_L100_H1.1270.97
600_L604_A1.1260.97
213_N218_K1.1250.97
528_A622_V1.1240.97
215_Q220_T1.1220.97
218_K222_A1.1200.97
347_T350_S1.1200.97
97_L100_H1.1180.96
394_A408_S1.1170.96
225_K228_K1.1160.96
562_N570_P1.1090.96
439_K552_E1.1060.96
495_M576_V1.1050.96
325_P423_S1.1020.96
533_V537_E1.0970.96
722_Y758_M1.0940.96
324_D426_E1.0870.96
22_L171_I1.0860.96
764_V776_L1.0840.96
316_M489_K1.0840.96
481_I495_M1.0790.96
199_Q203_F1.0780.96
97_L102_Q1.0740.96
404_I409_A1.0720.96
735_A765_G1.0700.95
548_T557_Y1.0680.95
286_L296_Q1.0660.95
311_N491_H1.0660.95
221_K225_K1.0650.95
195_F198_E1.0610.95
460_M463_L1.0580.95
219_K223_P1.0560.95
152_S161_S1.0550.95
620_V644_D1.0540.95
68_G410_I1.0540.95
502_M543_F1.0520.95
729_I775_V1.0450.95
280_E284_K1.0450.95
743_R760_E1.0450.95
42_G46_I1.0440.95
204_I208_K1.0440.95
49_F57_F1.0410.95
211_K215_Q1.0400.95
69_V73_W1.0400.95
597_I611_L1.0390.95
219_K222_A1.0370.95
395_A398_I1.0350.95
441_L454_L1.0310.94
339_E342_R1.0310.94
623_I647_T1.0300.94
94_S172_G1.0300.94
299_V303_P1.0290.94
149_F161_S1.0280.94
496_M532_V1.0270.94
503_V677_Q1.0260.94
213_N216_S1.0250.94
336_N417_A1.0230.94
174_I181_L1.0230.94
643_T647_T1.0200.94
323_A685_E1.0190.94
737_V764_V1.0160.94
300_S303_P1.0150.94
344_L395_A1.0130.94
358_T372_Y1.0080.94
271_E274_V1.0080.94
427_V443_G1.0070.94
642_Q677_Q1.0070.94
217_S220_T1.0050.94
763_V777_L1.0050.94
745_R753_R1.0020.94
298_T306_F0.9990.93
91_I169_I0.9940.93
353_V377_V0.9920.93
748_Y755_I0.9920.93
700_Q703_E0.9920.93
344_L414_V0.9910.93
216_S220_T0.9880.93
337_I505_L0.9880.93
229_P233_K0.9870.93
496_M528_A0.9860.93
737_V749_T0.9860.93
498_I579_V0.9810.93
302_P308_E0.9780.93
730_V763_V0.9750.93
210_F216_S0.9750.93
218_K223_P0.9740.93
299_V304_M0.9740.93
755_I775_V0.9710.92
691_D694_I0.9700.92
209_S213_N0.9630.92
203_F207_M0.9620.92
387_D600_L0.9600.92
51_F143_M0.9600.92
377_V384_N0.9590.92
379_V403_P0.9590.92
270_E273_P0.9580.92
192_I196_I0.9580.92
457_L754_L0.9570.92
459_K660_R0.9560.92
225_K230_A0.9540.92
404_I407_K0.9520.92
535_E538_R0.9500.92
749_T767_Y0.9490.92
502_M683_D0.9490.92
345_E355_A0.9470.92
47_Y51_F0.9470.92
271_E275_I0.9460.91
296_Q302_P0.9450.91
541_E603_M0.9450.91
208_K226_K0.9440.91
219_K224_S0.9430.91
274_V277_K0.9420.91
270_E274_V0.9400.91
743_R772_P0.9380.91
93_A101_V0.9370.91
548_T683_D0.9370.91
220_T224_S0.9360.91
735_A764_V0.9330.91
424_L482_T0.9330.91
180_S183_E0.9320.91
99_S106_N0.9310.91
191_P195_F0.9260.91
97_L101_V0.9240.90
636_A643_T0.9240.90
503_V543_F0.9230.90
541_E545_H0.9220.90
316_M696_Q0.9220.90
159_T162_Q0.9210.90
717_V757_A0.9210.90
344_L393_L0.9210.90
720_E745_R0.9190.90
352_G386_S0.9190.90
728_L740_L0.9170.90
213_N219_K0.9170.90
633_S636_A0.9160.90
204_I207_M0.9160.90
227_Q233_K0.9160.90
519_V607_A0.9160.90
84_R94_S0.9150.90
368_K631_I0.9140.90
380_S601_S0.9130.90
722_Y757_A0.9080.90
214_M227_Q0.9060.90
641_S644_D0.9050.90
477_V505_L0.8980.89
369_Y379_V0.8980.89
759_E766_P0.8970.89
694_I701_Y0.8960.89
298_T303_P0.8900.89
342_R346_R0.8900.89
272_S275_I0.8890.89
366_V479_G0.8890.89
428_L755_I0.8880.89
635_I665_F0.8880.89
595_D598_T0.8870.89
295_D300_S0.8870.89
87_G172_G0.8870.89
298_T301_A0.8860.89
715_S757_A0.8840.88
160_G163_I0.8820.88
275_I279_A0.8820.88
33_I699_A0.8800.88
496_M516_A0.8800.88
717_V745_R0.8780.88
401_E543_F0.8760.88
692_H695_T0.8760.88
212_S215_Q0.8750.88
218_K221_K0.8730.88
395_A402_A0.8700.88
210_F214_M0.8700.88
666_L669_G0.8690.88
86_A95_I0.8680.88
225_K229_P0.8670.87
350_S375_V0.8670.87
163_I166_I0.8670.87
568_K571_E0.8660.87
740_L744_F0.8660.87
181_L578_I0.8650.87
219_K227_Q0.8640.87
534_N603_M0.8610.87
31_S64_L0.8610.87
61_L68_G0.8590.87
275_I281_P0.8590.87
223_P230_A0.8580.87
745_R768_E0.8570.87
25_L28_I0.8530.87
223_P226_K0.8490.86
400_I410_I0.8490.86
344_L409_A0.8480.86
476_C637_F0.8470.86
373_P391_L0.8440.86
275_I278_R0.8430.86
209_S225_K0.8430.86
204_I211_K0.8430.86
579_V597_I0.8430.86
373_P377_V0.8430.86
26_L167_V0.8420.86
225_K231_R0.8410.86
97_L165_A0.8390.86
465_V545_H0.8380.86
225_K232_K0.8370.86
720_E724_E0.8350.85
290_Q294_G0.8330.85
28_I32_I0.8320.85
27_C68_G0.8320.85
287_Q292_E0.8310.85
392_A403_P0.8280.85
607_A640_S0.8270.85
496_M705_M0.8270.85
765_G770_S0.8260.85
93_A97_L0.8260.85
335_K339_E0.8260.85
401_E672_K0.8240.85
293_T296_Q0.8240.85
320_D688_K0.8220.85
338_Y360_V0.8220.85
222_A225_K0.8210.84
530_K596_S0.8210.84
286_L290_Q0.8200.84
729_I746_I0.8200.84
228_K233_K0.8200.84
172_G175_L0.8190.84
294_G302_P0.8190.84
299_V307_T0.8180.84
214_M220_T0.8180.84
465_V613_I0.8170.84
297_E302_P0.8170.84
369_Y414_V0.8170.84
50_R498_I0.8150.84
422_V449_S0.8150.84
278_R281_P0.8150.84
207_M211_K0.8140.84
42_G160_G0.8120.84
279_A282_V0.8120.84
217_S223_P0.8090.84
273_P277_K0.8070.83
351_F407_K0.8060.83
156_F161_S0.8050.83
302_P306_F0.8030.83
509_N518_V0.8030.83
62_L66_V0.8020.83
152_S165_A0.8010.83
103_L106_N0.8010.83
211_K214_M0.7990.83
430_S433_N0.7990.83
457_L745_R0.7970.83
288_D292_E0.7970.83
734_T749_T0.7950.83
480_I590_S0.7940.82
289_I292_E0.7930.82
215_Q219_K0.7930.82
224_S228_K0.7920.82
587_M598_T0.7900.82
94_S101_V0.7890.82
734_T752_A0.7890.82
620_V643_T0.7880.82
737_V752_A0.7880.82
286_L299_V0.7850.82
95_I169_I0.7850.82
693_V696_Q0.7840.82
39_G160_G0.7840.82
755_I764_V0.7840.82
53_A60_C0.7830.82
737_V767_Y0.7810.81
336_N339_E0.7810.81
297_E303_P0.7800.81
56_W59_L0.7790.81
203_F226_K0.7790.81
189_M192_I0.7790.81
738_S759_E0.7780.81
28_I31_S0.7770.81
84_R87_G0.7750.81
666_L671_N0.7750.81
34_A37_Q0.7740.81
314_Y696_Q0.7730.81
463_L476_C0.7720.81
393_L414_V0.7720.81
728_L732_M0.7710.81
526_S596_S0.7710.81
626_V732_M0.7690.80
538_R541_E0.7690.80
319_L424_L0.7670.80
217_S225_K0.7660.80
380_S387_D0.7650.80
207_M226_K0.7650.80
355_A631_I0.7640.80
582_L672_K0.7630.80
613_I631_I0.7630.80
510_G690_V0.7620.80
386_S656_K0.7620.80
301_A306_F0.7620.80
621_D638_S0.7620.80
704_E707_P0.7610.80
207_M221_K0.7610.80
205_D208_K0.7600.80
488_A667_P0.7570.79
227_Q230_A0.7570.79
515_L705_M0.7570.79
296_Q301_A0.7560.79
424_L443_G0.7550.79
221_K228_K0.7550.79
543_F683_D0.7550.79
210_F217_S0.7540.79
722_Y729_I0.7540.79
744_F749_T0.7530.79
403_P771_K0.7520.79
734_T739_M0.7520.79
486_M689_V0.7510.79
433_N487_R0.7510.79
52_F143_M0.7500.79
507_V690_V0.7490.79
212_S221_K0.7490.79
455_A667_P0.7480.79
391_L403_P0.7470.78
34_A44_T0.7470.78
301_A307_T0.7460.78
534_N538_R0.7460.78
344_L525_A0.7460.78
353_V384_N0.7450.78
187_K191_P0.7440.78
270_E281_P0.7420.78
444_L463_L0.7420.78
735_A772_P0.7410.78
22_L26_L0.7400.78
369_Y589_A0.7400.78
395_A414_V0.7400.78
294_G305_T0.7390.78
368_K456_E0.7380.78
21_E177_T0.7360.77
208_K219_K0.7360.77
497_M505_L0.7350.77
734_T746_I0.7350.77
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46_I57_F0.7340.77
379_V383_V0.7330.77
429_E434_D0.7320.77
218_K229_P0.7320.77
297_E300_S0.7310.77
275_I283_S0.7310.77
355_A368_K0.7300.77
274_V278_R0.7300.77
219_K225_K0.7280.77
99_S105_K0.7270.77
721_L746_I0.7270.77
717_V754_L0.7260.76
760_E775_V0.7240.76
444_L603_M0.7200.76
724_E728_L0.7200.76
149_F153_H0.7200.76
204_I233_K0.7200.76
550_N604_A0.7190.76
276_E283_S0.7190.76
572_L579_V0.7190.76
295_D303_P0.7180.76
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765_G772_P0.7090.75
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678_G683_D0.7070.75
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365_A503_V0.7070.75
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637_F660_R0.7000.74
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348_F758_M0.6990.74
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60_C64_L0.6950.73
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369_Y550_N0.6910.73
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320_D425_K0.6900.73
738_S748_Y0.6900.73
314_Y524_K0.6890.73
446_R479_G0.6890.73
222_A226_K0.6890.73
220_T226_K0.6870.72
211_K220_T0.6850.72
197_K204_I0.6840.72
740_L746_I0.6830.72
229_P232_K0.6820.72
752_A756_D0.6810.72
643_T652_G0.6810.72
21_E75_K0.6800.72
430_S454_L0.6800.72
208_K212_S0.6800.72
603_M752_A0.6800.72
277_K281_P0.6790.72
526_S638_S0.6790.72
550_N598_T0.6790.72
92_I99_S0.6780.71
286_L289_I0.6780.71
198_E202_A0.6780.71
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224_S229_P0.6750.71
352_G460_M0.6720.71
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640_S667_P0.6720.71
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391_L771_K0.6710.71
738_S743_R0.6710.71
226_K230_A0.6700.71
304_M308_E0.6700.71
370_E669_G0.6700.71
365_A543_F0.6700.71
276_E280_E0.6700.71
316_M491_H0.6680.70
468_A502_M0.6680.70
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319_L425_K0.6660.70
668_V671_N0.6660.70
471_S477_V0.6650.70
214_M226_K0.6650.70
46_I50_R0.6650.70
300_S305_T0.6630.70
765_G771_K0.6630.70
338_Y341_A0.6620.70
556_D674_V0.6620.70
388_D391_L0.6620.70
404_I597_I0.6610.69
498_I525_A0.6610.69
221_K226_K0.6600.69
347_T677_Q0.6600.69
721_L739_M0.6590.69
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298_T304_M0.6590.69
324_D429_E0.6580.69
192_I195_F0.6580.69
283_S291_P0.6580.69
207_M218_K0.6570.69
513_H516_A0.6570.69
212_S216_S0.6550.69
152_S156_F0.6540.69
372_Y408_S0.6530.69
316_M486_M0.6520.68
442_I457_L0.6510.68
703_E707_P0.6500.68
210_F221_K0.6500.68
729_I733_Q0.6500.68
337_I369_Y0.6500.68
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271_E278_R0.6400.67
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218_K232_K0.6340.66
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203_F206_D0.6310.66
301_A305_T0.6310.66
53_A579_V0.6300.66
620_V652_G0.6300.66
494_K572_L0.6290.66
380_S388_D0.6290.66
452_A642_Q0.6290.66
733_Q778_S0.6290.66
221_K224_S0.6280.66
50_R57_F0.6270.65
172_G176_V0.6260.65
173_M286_L0.6260.65
365_A642_Q0.6250.65
444_L476_C0.6240.65
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340_N585_L0.6230.65
272_S283_S0.6230.65
465_V603_M0.6210.65
92_I103_L0.6200.65
321_L641_S0.6190.64
366_V621_D0.6190.64
394_A623_I0.6190.64
544_S660_R0.6180.64
189_M193_G0.6180.64
438_A487_R0.6160.64
197_K233_K0.6150.64
214_M219_K0.6140.64
45_F278_R0.6120.64
524_K589_A0.6120.64
226_K229_P0.6120.64
224_S234_Q0.6110.63
321_L688_K0.6110.63
378_K603_M0.6100.63
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600_L607_A0.6090.63
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397_D588_V0.6030.62
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383_V651_M0.6020.62
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528_A705_M0.5970.62
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408_S686_V0.5960.62
206_D213_N0.5960.62
96_L101_V0.5950.61
281_P284_K0.5950.61
356_K372_Y0.5950.61
294_G297_E0.5940.61
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496_M515_L0.5900.61
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217_S224_S0.5850.60
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392_A607_A0.5830.60
194_R202_A0.5820.60
215_Q274_V0.5800.59
733_Q766_P0.5800.59
296_Q305_T0.5790.59
402_A532_V0.5790.59
729_I759_E0.5790.59
365_A756_D0.5790.59
175_L180_S0.5790.59
299_V306_F0.5780.59
719_D753_R0.5780.59
65_L559_K0.5780.59
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32_I320_D0.5750.59
214_M221_K0.5750.59
341_A348_F0.5740.59
733_Q775_V0.5730.59
575_I603_M0.5730.59
379_V387_D0.5710.58
471_S510_G0.5690.58
447_N453_V0.5690.58
215_Q233_K0.5680.58
516_A706_I0.5680.58
361_H368_K0.5680.58
323_A423_S0.5680.58
218_K225_K0.5670.58
395_A456_E0.5670.58
495_M593_V0.5660.58
318_S688_K0.5650.57
217_S233_K0.5650.57
488_A607_A0.5640.57
206_D233_K0.5630.57
381_K384_N0.5630.57
371_V392_A0.5610.57
197_K200_W0.5610.57
731_G743_R0.5600.57
521_D530_K0.5600.57
375_V729_I0.5590.57
702_Q706_I0.5590.57
26_L30_I0.5590.57
506_N732_M0.5590.57
393_L663_M0.5580.57
223_P227_Q0.5580.57
543_F642_Q0.5580.57
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534_N541_E0.5550.56
355_A362_L0.5550.56
631_I673_P0.5550.56
400_I403_P0.5540.56
524_K585_L0.5540.56
270_E275_I0.5540.56
456_E665_F0.5540.56
488_A758_M0.5540.56
629_A667_P0.5540.56
204_I209_S0.5540.56
421_M680_F0.5530.56
292_E310_E0.5530.56
619_S647_T0.5530.56
321_L405_P0.5520.56
598_T650_D0.5520.56
391_L400_I0.5520.56
377_V408_S0.5510.56
471_S683_D0.5510.56
64_L94_S0.5510.56
427_V745_R0.5500.55
465_V676_V0.5490.55
716_E761_R0.5490.55
369_Y641_S0.5490.55
221_K229_P0.5490.55
295_D301_A0.5490.55
456_E552_E0.5480.55
518_V639_V0.5480.55
218_K224_S0.5470.55
497_M731_G0.5470.55
34_A61_L0.5470.55
274_V281_P0.5470.55
551_I699_A0.5460.55
220_T225_K0.5460.55
222_A232_K0.5450.55
388_D601_S0.5440.55
680_F683_D0.5440.55
593_V613_I0.5440.55
402_A592_D0.5440.55
547_G687_E0.5440.55
150_A154_F0.5440.55
750_R763_V0.5430.55
316_M514_L0.5430.55
218_K226_K0.5420.54
732_M775_V0.5420.54
745_R749_T0.5420.54
735_A775_V0.5410.54
521_D553_G0.5410.54
602_Q629_A0.5410.54
638_S722_Y0.5400.54
216_S287_Q0.5400.54
87_G100_H0.5400.54
292_E301_A0.5400.54
211_K218_K0.5400.54
493_V678_G0.5390.54
189_M196_I0.5390.54
394_A677_Q0.5380.54
394_A503_V0.5380.54
511_I686_V0.5370.54
728_L775_V0.5370.54
502_M520_T0.5370.54
379_V424_L0.5360.54
681_L689_V0.5360.54
612_I636_A0.5360.54
277_K282_V0.5350.53
216_S222_A0.5350.53
532_V600_L0.5350.53
341_A374_D0.5350.53
553_G680_F0.5350.53
763_V776_L0.5340.53
496_M531_K0.5340.53
368_K590_S0.5340.53
549_R623_I0.5330.53
666_L673_P0.5330.53
373_P395_A0.5330.53
215_Q221_K0.5330.53
179_R184_T0.5330.53
179_R185_L0.5330.53
207_M225_K0.5320.53
214_M222_A0.5320.53
403_P582_L0.5310.53
477_V578_I0.5300.53
511_I514_L0.5300.53
528_A535_E0.5300.53
348_F521_D0.5300.53
595_D673_P0.5290.53
62_L551_I0.5290.53
665_F676_V0.5290.53
638_S672_K0.5290.53
220_T232_K0.5280.53
381_K547_G0.5280.53
315_E696_Q0.5280.53
232_K271_E0.5270.52
30_I90_C0.5270.52
296_Q307_T0.5270.52
579_V748_Y0.5250.52
355_A761_R0.5250.52
283_S297_E0.5250.52
42_G679_A0.5240.52
460_M604_A0.5240.52
468_A629_A0.5240.52
280_E283_S0.5240.52
94_S103_L0.5230.52
391_L494_K0.5230.52
230_A233_K0.5220.52
59_L197_K0.5220.52
37_Q42_G0.5210.52
98_L183_E0.5210.52
427_V510_G0.5210.52
348_F486_M0.5210.52
100_H104_F0.5200.51
621_D640_S0.5190.51
487_R611_L0.5190.51
179_R755_I0.5190.51
442_I638_S0.5180.51
287_Q303_P0.5180.51
272_S280_E0.5180.51
213_N289_I0.5170.51
297_E305_T0.5160.51
355_A636_A0.5150.51
727_E779_K0.5150.51
723_D726_V0.5150.51
526_S533_V0.5150.51
212_S219_K0.5150.51
230_A289_I0.5140.51
480_I497_M0.5120.50
65_L148_L0.5120.50
378_K448_I0.5120.50
64_L578_I0.5120.50
768_E772_P0.5110.50
302_P312_K0.5100.50
340_N398_I0.5100.50
185_L201_L0.5100.50
88_L91_I0.5100.50
285_P294_G0.5090.50
532_V596_S0.5090.50
598_T643_T0.5090.50
617_R647_T0.5090.50
693_V728_L0.5080.50
256_S271_E0.5080.50
291_P381_K0.5080.50
495_M516_A0.5080.50
476_C674_V0.5080.50
226_K232_K0.5070.50
25_L29_A0.5070.50
70_S74_K0.5070.50
525_A621_D0.5070.50
742_R752_A0.5070.50
133_S136_S0.5060.50
585_L588_V0.5040.49
68_G743_R0.5040.49
225_K275_I0.5040.49
214_M256_S0.5030.49
601_S629_A0.5020.49
273_P283_S0.5020.49
276_E279_A0.5020.49
476_C660_R0.5020.49
204_I210_F0.5020.49
222_A229_P0.5020.49
498_I676_V0.5010.49
369_Y702_Q0.5010.49
375_V378_K0.5000.49
145_G547_G0.5000.49
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2iusA 1 0.4879 100 0.473 Contact Map
2iutA 2 0.4981 100 0.481 Contact Map
4nh0A 1 0.4206 100 0.854 Contact Map
2ve8A 1 0.0864 100 0.896 Contact Map
4lyaA 1 0.4219 100 0.899 Contact Map
4d2iA 3 0.4104 99.9 0.913 Contact Map
4ag6A 2 0.3088 99.7 0.935 Contact Map
1e9rA 3 0.3647 99.3 0.951 Contact Map
2qbyA 1 0.3875 98.4 0.965 Contact Map
1fnnA 1 0.385 98.3 0.966 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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