GREMLIN Database
RL17 - 50S ribosomal protein L17
UniProt: P20277 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 120 (110)
Sequences: 2266 (1069)
Seq/√Len: 102.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
4_R39_E3.0281.00
34_E115_A2.8141.00
28_E82_K2.7771.00
29_R118_E2.6961.00
40_L117_I2.6121.00
26_I68_N2.4631.00
12_Q19_D2.2881.00
48_I119_L2.2141.00
25_I44_V2.1581.00
24_L44_V2.0541.00
25_I119_L1.9501.00
21_T44_V1.9461.00
81_Q85_S1.7991.00
100_R118_E1.7851.00
34_E103_K1.7501.00
28_E90_R1.7171.00
57_H61_Q1.6541.00
62_A84_F1.6281.00
16_M36_R1.6001.00
19_D23_D1.5611.00
63_A80_L1.5351.00
31_E116_I1.5101.00
54_G58_A1.4981.00
10_S14_K1.4441.00
50_L62_A1.4311.00
21_T43_V1.4301.00
61_Q65_Y1.4091.00
16_M20_L1.4081.00
85_S89_T1.4031.00
55_D58_A1.3821.00
29_R116_I1.3710.99
39_E42_S1.3600.99
99_T117_I1.3120.99
32_T37_A1.2760.99
31_E104_L1.2650.99
104_L116_I1.2640.99
21_T47_M1.2550.99
51_G88_A1.2460.99
8_R13_R1.2420.99
56_L60_R1.2380.99
94_R120_V1.2160.99
82_K86_D1.2020.99
6_L39_E1.1610.98
8_R36_R1.1570.98
22_T79_A1.1540.98
18_R22_T1.1540.98
53_R58_A1.1510.98
63_A81_Q1.1360.98
101_I115_A1.1340.98
58_A61_Q1.1330.98
12_Q16_M1.1200.98
106_P111_G1.1000.98
13_R39_E1.0940.97
16_M23_D1.0660.97
45_E101_I1.0510.97
25_I79_A1.0480.97
18_R67_R1.0450.97
104_L114_M1.0430.97
51_G83_L1.0280.96
34_E113_P1.0010.96
28_E87_I1.0000.96
42_S46_K0.9710.95
50_L61_Q0.9710.95
22_T67_R0.9590.95
47_M65_Y0.9570.95
9_T12_Q0.9420.94
54_G59_R0.9380.94
59_R84_F0.9380.94
106_P113_P0.9120.93
66_I79_A0.9090.93
42_S45_E0.9010.93
31_E114_M0.8890.92
17_L20_L0.8730.91
23_D26_I0.8720.91
89_T92_E0.8670.91
61_Q64_A0.8640.91
105_G113_P0.8590.91
22_T66_I0.8500.90
53_R57_H0.8490.90
8_R16_M0.8400.90
47_M83_L0.8400.90
17_L43_V0.8390.90
59_R80_L0.8350.89
56_L63_A0.8170.88
33_T112_A0.8040.88
24_L117_I0.8040.88
44_V99_T0.8030.88
48_I91_Y0.7990.87
46_K50_L0.7940.87
28_E91_Y0.7940.87
41_R101_I0.7890.87
86_D89_T0.7860.86
23_D27_N0.7840.86
43_V65_Y0.7820.86
26_I79_A0.7790.86
41_R45_E0.7770.86
41_R117_I0.7660.85
57_H60_R0.7630.85
25_I87_I0.7570.84
62_A80_L0.7490.84
91_Y119_L0.7480.84
3_Y17_L0.7470.83
83_L87_I0.7450.83
5_K9_T0.7440.83
17_L40_L0.7340.82
40_L43_V0.7230.81
20_L23_D0.7190.81
108_R114_M0.6880.78
47_M50_L0.6820.78
56_L59_R0.6790.77
20_L40_L0.6740.77
3_Y42_S0.6670.76
28_E86_D0.6630.76
107_R114_M0.6620.75
21_T40_L0.6600.75
21_T65_Y0.6560.75
27_N95_Q0.6540.75
49_T98_Y0.6540.75
102_M120_V0.6530.74
14_K18_R0.6470.74
50_L53_R0.6410.73
63_A77_Q0.6390.73
105_G114_M0.6360.72
62_A83_L0.6300.72
6_L16_M0.6280.72
4_R35_T0.6230.71
25_I83_L0.6170.70
24_L40_L0.6150.70
51_G62_A0.6060.69
111_G114_M0.5960.68
7_G35_T0.5940.67
35_T113_P0.5870.66
49_T96_G0.5840.66
34_E114_M0.5810.66
59_R63_A0.5780.65
82_K91_Y0.5730.65
12_Q15_A0.5680.64
87_I91_Y0.5670.64
51_G54_G0.5650.63
9_T36_R0.5620.63
6_L12_Q0.5610.63
96_G115_A0.5560.62
19_D45_E0.5550.62
60_R66_I0.5530.62
54_G62_A0.5510.62
21_T45_E0.5510.62
45_E52_K0.5480.61
45_E98_Y0.5410.60
12_Q36_R0.5400.60
13_R16_M0.5400.60
18_R108_R0.5270.58
37_A115_A0.5240.58
107_R110_D0.5240.58
80_L84_F0.5200.57
52_K94_R0.5190.57
35_T115_A0.5190.57
22_T68_N0.5170.57
86_D91_Y0.5170.57
26_I78_D0.5160.57
63_A67_R0.5150.56
64_A67_R0.5080.55
35_T112_A0.5080.55
52_K95_Q0.5070.55
16_M30_I0.5010.54
41_R98_Y0.5000.54
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bboP 1 0.9333 100 0.027 Contact Map
3j3wN 1 1 100 0.035 Contact Map
2zjrK 1 0.925 100 0.039 Contact Map
4tp9N 1 0.9333 100 0.042 Contact Map
1gd8A 1 0.8583 100 0.045 Contact Map
3j7yO 1 0.9333 100 0.061 Contact Map
1vw4L 1 0.9667 100 0.082 Contact Map
2bkmA 1 0.45 8.2 0.945 Contact Map
1ux8A 1 0.3917 6.4 0.948 Contact Map
1yxbA 4 0.3333 4.9 0.95 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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