GREMLIN Database
RL30 - 50S ribosomal protein L30
UniProt: P19947 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 59 (57)
Sequences: 1485 (700)
Seq/√Len: 92.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
39_D44_R3.2081.00
12_V23_V2.5801.00
48_N51_S2.5091.00
7_T34_T2.2341.00
17_E21_V2.1601.00
18_D49_K2.1251.00
19_Q52_H2.1121.00
8_L23_V2.0491.00
5_E57_K2.0371.00
29_K33_Q2.0151.00
23_V50_V1.6661.00
9_K55_S1.6531.00
37_H43_I1.5731.00
3_K36_V1.5681.00
5_E36_V1.5251.00
6_I37_H1.3510.99
7_T57_K1.3200.99
21_V25_T1.2820.99
7_T55_S1.2540.99
3_K38_E1.2470.99
4_L47_I1.2010.98
21_V24_R1.1880.98
30_K33_Q1.1500.97
12_V24_R1.1470.97
22_T46_M1.0840.96
16_P19_Q1.0820.96
43_I46_M1.0400.95
4_L39_D1.0390.95
25_T46_M1.0230.95
4_L44_R1.0220.95
8_L12_V0.9930.94
25_T42_A0.9880.94
22_T49_K0.9520.93
38_E43_I0.9110.91
39_D47_I0.9100.91
19_Q49_K0.9020.91
25_T37_H0.9000.91
8_L33_Q0.8840.90
12_V20_R0.8710.89
10_R15_R0.8000.85
16_P20_R0.7650.82
17_E20_R0.7520.81
15_R19_Q0.7490.81
20_R24_R0.7370.79
4_L58_E0.7340.79
17_E24_R0.7340.79
8_L31_T0.7100.77
5_E34_T0.6950.75
24_R29_K0.6930.75
16_P52_H0.6910.75
16_P22_T0.6880.75
40_N43_I0.6860.74
28_L31_T0.6830.74
4_L36_V0.6830.74
16_P49_K0.6710.73
6_I35_V0.6630.72
37_H46_M0.6530.71
22_T37_H0.6500.70
10_R29_K0.6480.70
2_A39_D0.6450.70
38_E42_A0.6450.70
10_R16_P0.6430.70
47_I54_V0.6410.69
18_D22_T0.6360.69
6_I43_I0.6290.68
34_T57_K0.6200.67
15_R53_L0.6090.65
15_R51_S0.6020.65
2_A38_E0.5970.64
22_T25_T0.5860.62
3_K34_T0.5490.58
23_V28_L0.5470.57
12_V15_R0.5450.57
2_A42_A0.5360.56
15_R20_R0.5260.54
4_L57_K0.5180.53
23_V33_Q0.5160.53
12_V33_Q0.5160.53
41_A54_V0.5140.53
35_V43_I0.5110.52
23_V29_K0.5110.52
10_R14_G0.5060.52
44_R47_I0.5050.51
26_L37_H0.5040.51
22_T43_I0.5030.51
42_A54_V0.5000.51
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1vw4U 1 0.9831 99.9 0.181 Contact Map
4tp9Z 1 0.0339 99.9 0.196 Contact Map
1bxyA 1 1 99.8 0.209 Contact Map
3j7yZ 1 1 99.8 0.228 Contact Map
3j3vY 1 0.9492 99.8 0.24 Contact Map
2zjrW 1 0.9322 99.8 0.25 Contact Map
3j21Y 1 1 99.8 0.288 Contact Map
1vq8W 1 0.9661 99.7 0.34 Contact Map
1vx75 1 1 99.6 0.361 Contact Map
4w20F 1 1 99.6 0.363 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0047 seconds.