DHOM - BACSU - GREMLIN Contacts

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DHOM - Homoserine dehydrogenase

UniProt:	P19582	Sequences: MKAIRVGLLGLGTVGSGVVKIIQDHQDKLMHQVGCPVTIKKVLVKDLEKKREVDLPKEVLTTEVYDVIDDPDVDVVIEVIGGVEQTKQYLVDALRSKKHVVTANKDLMAVYGSELLAEAKENGCDIYFEASVAGGIPILRTLEEGLSSDRITKMMGIVNGTTNFILTKMIKEKSPYEEVLKEAQDLGFAEADPTSDVEGLDAARKMAILARLGFSMNVDLEDVKVKGISQITDEDISFSKRLGYTMKLIGIAQRDGSKIEVSVQPTLLPDHHPLSAVHNEFNAVYVYGEAVGETMFYGPGAGSMPTATSVVSDLVAVMKNMRLGVTGNSFVGPQYEKNMKSPSDIYAQQFLRIHVKDEVGSFSKITSVFSERGVSFEKILQLPIKGHDELAEIVIVTHHTSEADFSDILQNLNDLEVVQEVKSTYRVEGNGWS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	433 (422)
Sequences:	2384 (1522)
Seq/√Len:	74.1

BACSU - DHOM
HALSA - Q9HM88
SULSO - Q7LXP8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
198_E	229_S	6.683	1.00
168_K	172_E	4.652	1.00
84_E	88_Q	4.288	1.00
91_V	118_E	3.864	1.00
115_L	126_I	3.752	1.00
5_R	38_T	3.683	1.00
176_Y	197_V	3.531	1.00
63_E	66_D	3.320	1.00
194_T	198_E	3.245	1.00
181_K	185_D	3.137	1.00
77_I	314_L	3.112	1.00
175_P	178_E	2.923	1.00
65_Y	92_D	2.817	1.00
19_V	39_I	2.759	1.00
174_S	179_V	2.725	1.00
87_K	91_V	2.530	1.00
94_L	124_C	2.489	1.00
69_D	92_D	2.451	1.00
182_E	185_D	2.438	1.00
241_R	382_L	2.430	1.00
20_K	303_S	2.416	1.00
164_F	182_E	2.372	1.00
135_G	291_V	2.356	1.00
117_A	121_E	2.262	1.00
8_L	19_V	2.260	1.00
371_E	411_N	2.235	1.00
108_M	208_I	2.226	1.00
5_R	40_K	2.214	1.00
175_P	179_V	2.156	1.00
281_F	299_P	2.131	1.00
188_F	280_E	2.106	1.00
17_G	303_S	2.105	1.00
149_D	289_E	2.089	1.00
288_G	291_V	2.071	1.00
30_M	36_P	2.052	1.00
91_V	114_E	2.046	1.00
138_I	286_V	1.991	1.00
153_K	253_Q	1.972	1.00
141_T	296_F	1.905	1.00
40_K	70_D	1.902	1.00
372_R	411_N	1.900	1.00
240_K	270_D	1.883	1.00
46_D	51_R	1.866	1.00
108_M	126_I	1.864	1.00
224_K	342_P	1.862	1.00
90_L	107_L	1.843	1.00
95_R	118_E	1.841	1.00
21_I	307_A	1.838	1.00
245_T	270_D	1.814	1.00
18_V	311_V	1.799	1.00
90_L	100_V	1.795	1.00
357_D	398_H	1.790	1.00
94_L	118_E	1.787	1.00
41_K	70_D	1.786	1.00
401_S	404_D	1.768	1.00
29_L	315_V	1.766	1.00
214_F	252_A	1.703	1.00
95_R	121_E	1.702	1.00
91_V	115_L	1.695	1.00
147_S	315_V	1.692	1.00
346_Y	399_H	1.691	1.00
206_M	261_V	1.690	1.00
40_K	72_D	1.668	1.00
95_R	122_N	1.667	1.00
91_V	95_R	1.655	1.00
174_S	182_E	1.650	1.00
43_L	64_V	1.649	1.00
90_L	126_I	1.638	1.00
3_A	38_T	1.632	1.00
3_A	36_P	1.613	0.99
110_V	221_E	1.613	0.99
47_L	62_T	1.606	0.99
92_D	96_S	1.591	0.99
154_M	213_G	1.578	0.99
239_S	267_L	1.578	0.99
272_H	285_Y	1.576	0.99
253_Q	260_E	1.576	0.99
20_K	24_D	1.575	0.99
41_K	66_D	1.575	0.99
99_H	124_C	1.553	0.99
75_V	314_L	1.538	0.99
3_A	35_C	1.524	0.99
5_R	72_D	1.523	0.99
19_V	23_Q	1.518	0.99
367_S	371_E	1.517	0.99
61_T	66_D	1.513	0.99
280_E	299_P	1.510	0.99
179_V	182_E	1.506	0.99
372_R	407_D	1.500	0.99
291_V	294_T	1.481	0.99
255_D	258_K	1.479	0.99
64_V	93_A	1.467	0.99
206_M	250_G	1.465	0.99
118_E	122_N	1.460	0.99
277_V	297_Y	1.460	0.99
16_S	303_S	1.456	0.99
170_I	236_I	1.454	0.99
153_K	287_Y	1.454	0.99
210_A	252_A	1.452	0.99
287_Y	293_E	1.451	0.99
168_K	179_V	1.441	0.99
200_L	225_V	1.440	0.99
174_S	178_E	1.438	0.99
41_K	73_V	1.433	0.99
359_V	370_S	1.431	0.99
79_V	310_V	1.431	0.99
210_A	261_V	1.430	0.99
111_Y	114_E	1.428	0.99
99_H	317_V	1.413	0.99
219_D	222_D	1.411	0.99
195_S	204_R	1.397	0.99
77_I	101_V	1.394	0.98
239_S	246_M	1.387	0.98
94_L	126_I	1.386	0.98
149_D	308_T	1.384	0.98
152_T	287_Y	1.383	0.98
46_D	49_K	1.382	0.98
164_F	168_K	1.378	0.98
181_K	184_Q	1.376	0.98
6_V	314_L	1.374	0.98
171_K	278_H	1.371	0.98
173_K	233_D	1.362	0.98
355_V	418_V	1.360	0.98
43_L	89_Y	1.359	0.98
376_F	379_I	1.349	0.98
267_L	425_Y	1.348	0.98
133_A	284_V	1.341	0.98
410_Q	413_N	1.340	0.98
281_F	297_Y	1.333	0.98
210_A	223_V	1.331	0.98
47_L	60_L	1.326	0.98
68_I	89_Y	1.319	0.98
251_I	264_Q	1.317	0.98
286_V	296_F	1.317	0.98
140_R	144_E	1.310	0.98
226_K	264_Q	1.301	0.98
69_D	96_S	1.299	0.98
87_K	111_Y	1.294	0.98
33_V	36_P	1.281	0.97
165_I	180_L	1.278	0.97
9_L	43_L	1.271	0.97
344_D	401_S	1.271	0.97
97_K	122_N	1.269	0.97
85_Q	88_Q	1.264	0.97
65_Y	68_I	1.263	0.97
390_L	419_Q	1.261	0.97
9_L	89_Y	1.257	0.97
17_G	304_M	1.251	0.97
273_P	295_M	1.237	0.97
180_L	189_A	1.236	0.97
67_V	70_D	1.234	0.97
26_Q	36_P	1.234	0.97
170_I	240_K	1.215	0.96
140_R	316_A	1.208	0.96
41_K	61_T	1.207	0.96
364_K	417_V	1.207	0.96
375_S	398_H	1.200	0.96
22_I	39_I	1.194	0.96
5_R	74_D	1.190	0.96
356_K	419_Q	1.189	0.96
33_V	37_V	1.179	0.96
264_Q	426_R	1.178	0.96
9_L	67_V	1.170	0.96
167_T	171_K	1.170	0.96
25_H	29_L	1.159	0.95
188_F	279_N	1.157	0.95
4_I	318_M	1.154	0.95
162_T	202_A	1.142	0.95
410_Q	414_D	1.140	0.95
170_I	245_T	1.137	0.95
106_D	204_R	1.133	0.95
125_D	320_N	1.133	0.95
85_Q	89_Y	1.129	0.95
94_L	115_L	1.127	0.94
92_D	95_R	1.127	0.94
292_G	299_P	1.121	0.94
21_I	290_A	1.120	0.94
94_L	122_N	1.119	0.94
311_V	314_L	1.116	0.94
344_D	403_A	1.114	0.94
375_S	381_Q	1.112	0.94
279_N	299_P	1.104	0.94
6_V	37_V	1.103	0.94
142_L	151_I	1.100	0.94
88_Q	92_D	1.099	0.94
65_Y	69_D	1.086	0.93
11_L	42_V	1.076	0.93
360_G	381_Q	1.071	0.93
37_V	318_M	1.071	0.93
44_V	60_L	1.070	0.93
47_L	61_T	1.068	0.93
40_K	73_V	1.066	0.93
165_I	176_Y	1.066	0.93
83_V	111_Y	1.063	0.93
44_V	49_K	1.061	0.93
18_V	307_A	1.054	0.92
33_V	315_V	1.054	0.92
148_S	312_S	1.044	0.92
73_V	98_K	1.044	0.92
168_K	279_N	1.043	0.92
67_V	76_V	1.041	0.92
362_F	379_I	1.040	0.92
360_G	375_S	1.039	0.92
251_I	262_S	1.038	0.92
351_L	405_F	1.036	0.92
203_A	225_V	1.031	0.91
364_K	367_S	1.023	0.91
357_D	360_G	1.022	0.91
369_F	408_I	1.016	0.91
226_K	402_E	1.015	0.91
26_Q	30_M	1.013	0.91
168_K	174_S	1.011	0.91
118_E	121_E	1.010	0.91
207_A	223_V	1.002	0.90
11_L	19_V	1.002	0.90
158_V	206_M	0.995	0.90
415_L	418_V	0.994	0.90
290_A	304_M	0.994	0.90
194_T	229_S	0.994	0.90
168_K	182_E	0.988	0.90
44_V	89_Y	0.986	0.89
402_E	406_S	0.981	0.89
226_K	230_Q	0.978	0.89
4_I	75_V	0.977	0.89
355_V	361_S	0.973	0.89
277_V	283_A	0.972	0.89
226_K	426_R	0.970	0.89
373_G	404_D	0.963	0.88
363_S	367_S	0.963	0.88
413_N	421_V	0.963	0.88
150_R	254_R	0.960	0.88
43_L	61_T	0.959	0.88
19_V	55_L	0.954	0.88
4_I	321_M	0.950	0.88
5_R	73_V	0.949	0.88
249_I	266_T	0.949	0.88
161_T	189_A	0.947	0.87
224_K	264_Q	0.939	0.87
7_G	73_V	0.934	0.87
113_S	217_N	0.934	0.87
285_Y	293_E	0.934	0.87
25_H	289_E	0.933	0.87
353_I	395_I	0.931	0.87
23_Q	39_I	0.928	0.86
135_G	292_G	0.925	0.86
70_D	73_V	0.918	0.86
16_S	53_V	0.917	0.86
288_G	294_T	0.911	0.85
28_K	32_Q	0.908	0.85
24_D	289_E	0.906	0.85
162_T	248_L	0.906	0.85
16_S	52_E	0.905	0.85
141_T	145_G	0.902	0.85
231_I	425_Y	0.901	0.85
138_I	141_T	0.901	0.85
369_F	376_F	0.901	0.85
21_I	304_M	0.900	0.85
348_Q	377_E	0.893	0.84
176_Y	180_L	0.893	0.84
73_V	76_V	0.893	0.84
27_D	30_M	0.892	0.84
84_E	87_K	0.890	0.84
6_V	311_V	0.886	0.84
408_I	412_L	0.883	0.84
68_I	92_D	0.882	0.83
258_K	340_K	0.880	0.83
363_S	370_S	0.879	0.83
42_V	59_V	0.878	0.83
43_L	67_V	0.876	0.83
175_P	233_D	0.874	0.83
157_I	277_V	0.870	0.83
47_L	51_R	0.868	0.82
94_L	100_V	0.868	0.82
86_T	90_L	0.866	0.82
191_A	194_T	0.866	0.82
277_V	295_M	0.862	0.82
403_A	407_D	0.862	0.82
83_V	110_V	0.861	0.82
320_N	326_T	0.860	0.82
87_K	118_E	0.860	0.82
30_M	33_V	0.858	0.82
352_R	392_E	0.857	0.82
50_K	53_V	0.855	0.82
360_G	366_T	0.853	0.81
142_L	213_G	0.852	0.81
50_K	54_D	0.849	0.81
355_V	393_I	0.848	0.81
195_S	200_L	0.845	0.81
368_V	411_N	0.844	0.81
396_V	427_V	0.841	0.80
131_S	208_I	0.834	0.80
138_I	296_F	0.833	0.80
343_S	406_S	0.832	0.80
106_D	110_V	0.830	0.80
37_V	75_V	0.830	0.80
368_V	415_L	0.830	0.80
7_G	41_K	0.830	0.80
343_S	403_A	0.829	0.80
70_D	98_K	0.828	0.79
99_H	125_D	0.827	0.79
406_S	410_Q	0.825	0.79
41_K	67_V	0.824	0.79
127_Y	317_V	0.823	0.79
102_T	126_I	0.823	0.79
293_E	299_P	0.823	0.79
7_G	96_S	0.822	0.79
67_V	73_V	0.819	0.79
362_F	376_F	0.817	0.79
346_Y	401_S	0.810	0.78
150_R	289_E	0.807	0.78
264_Q	402_E	0.807	0.78
46_D	50_K	0.806	0.78
381_Q	391_A	0.805	0.77
363_S	366_T	0.804	0.77
358_E	416_E	0.802	0.77
216_M	259_I	0.802	0.77
184_Q	189_A	0.799	0.77
244_Y	267_L	0.796	0.77
200_L	229_S	0.791	0.76
413_N	422_K	0.791	0.76
93_A	173_K	0.790	0.76
351_L	369_F	0.789	0.76
7_G	70_D	0.788	0.76
360_G	398_H	0.787	0.76
262_S	426_R	0.786	0.76
7_G	67_V	0.779	0.75
106_D	195_S	0.778	0.75
246_M	267_L	0.775	0.75
258_K	344_D	0.774	0.75
139_L	212_L	0.774	0.75
236_I	246_M	0.772	0.74
44_V	51_R	0.772	0.74
6_V	77_I	0.771	0.74
115_L	118_E	0.770	0.74
402_E	426_R	0.767	0.74
144_E	316_A	0.767	0.74
400_T	404_D	0.761	0.73
242_L	380_L	0.757	0.73
357_D	381_Q	0.756	0.73
11_L	16_S	0.754	0.73
405_F	424_T	0.751	0.72
110_V	220_L	0.751	0.72
44_V	47_L	0.751	0.72
375_S	391_A	0.749	0.72
362_F	375_S	0.747	0.72
149_D	291_V	0.747	0.72
51_R	62_T	0.745	0.72
184_Q	193_P	0.745	0.72
409_L	413_N	0.745	0.72
145_G	294_T	0.744	0.72
312_S	316_A	0.743	0.72
48_E	62_T	0.741	0.71
233_D	237_S	0.740	0.71
206_M	252_A	0.739	0.71
164_F	167_T	0.738	0.71
18_V	314_L	0.738	0.71
140_R	149_D	0.736	0.71
407_D	411_N	0.734	0.71
381_Q	398_H	0.733	0.71
372_R	404_D	0.732	0.70
125_D	317_V	0.730	0.70
27_D	31_H	0.730	0.70
138_I	294_T	0.727	0.70
7_G	43_L	0.726	0.70
354_H	392_E	0.725	0.70
7_G	64_V	0.720	0.69
176_Y	229_S	0.720	0.69
217_N	331_V	0.718	0.69
90_L	115_L	0.717	0.69
32_Q	319_K	0.717	0.69
204_R	220_L	0.714	0.69
286_V	294_T	0.713	0.68
170_I	270_D	0.713	0.68
19_V	42_V	0.713	0.68
351_L	424_T	0.709	0.68
178_E	181_K	0.707	0.68
198_E	230_Q	0.707	0.68
354_H	390_L	0.703	0.67
48_E	51_R	0.703	0.67
207_A	220_L	0.702	0.67
391_A	395_I	0.701	0.67
370_S	379_I	0.700	0.67
22_I	26_Q	0.697	0.67
177_E	181_K	0.692	0.66
11_L	44_V	0.691	0.66
125_D	327_G	0.691	0.66
252_A	261_V	0.691	0.66
44_V	61_T	0.687	0.66
23_Q	56_P	0.687	0.66
154_M	209_L	0.684	0.65
55_L	58_E	0.683	0.65
210_A	218_V	0.682	0.65
378_K	382_L	0.682	0.65
132_V	139_L	0.681	0.65
171_K	279_N	0.680	0.65
177_E	221_E	0.678	0.65
170_I	278_H	0.677	0.64
23_Q	26_Q	0.676	0.64
245_T	278_H	0.676	0.64
59_V	70_D	0.676	0.64
70_D	74_D	0.675	0.64
142_L	209_L	0.675	0.64
108_M	116_L	0.671	0.64
161_T	180_L	0.671	0.64
197_V	310_V	0.669	0.64
133_A	136_I	0.665	0.63
45_K	89_Y	0.665	0.63
262_S	402_E	0.663	0.63
9_L	93_A	0.663	0.63
140_R	312_S	0.659	0.62
374_V	383_P	0.659	0.62
29_L	39_I	0.658	0.62
154_M	206_M	0.658	0.62
186_L	250_G	0.657	0.62
71_P	98_K	0.657	0.62
251_I	266_T	0.656	0.62
366_T	381_Q	0.655	0.62
353_I	365_I	0.654	0.62
97_K	124_C	0.654	0.62
5_R	70_D	0.654	0.62
56_P	59_V	0.653	0.62
134_G	305_P	0.651	0.61
42_V	53_V	0.651	0.61
67_V	71_P	0.650	0.61
155_M	285_Y	0.648	0.61
362_F	366_T	0.647	0.61
80_I	89_Y	0.646	0.61
280_E	305_P	0.646	0.61
87_K	114_E	0.645	0.61
273_P	285_Y	0.644	0.61
71_P	96_S	0.644	0.61
218_V	248_L	0.643	0.61
55_L	60_L	0.643	0.61
51_R	64_V	0.642	0.60
148_S	308_T	0.639	0.60
384_I	391_A	0.639	0.60
368_V	372_R	0.637	0.60
6_V	74_D	0.636	0.60
283_A	295_M	0.636	0.60
165_I	177_E	0.632	0.59
241_R	380_L	0.630	0.59
145_G	312_S	0.630	0.59
407_D	410_Q	0.628	0.59
393_I	398_H	0.626	0.58
359_V	373_G	0.625	0.58
146_L	308_T	0.625	0.58
251_I	402_E	0.625	0.58
17_G	305_P	0.625	0.58
362_F	398_H	0.624	0.58
25_H	32_Q	0.624	0.58
409_L	424_T	0.621	0.58
83_V	90_L	0.619	0.58
179_V	184_Q	0.619	0.58
158_V	250_G	0.618	0.57
371_E	414_D	0.618	0.57
55_L	59_V	0.618	0.57
80_I	85_Q	0.618	0.57
235_D	352_R	0.617	0.57
114_E	118_E	0.617	0.57
141_T	294_T	0.617	0.57
75_V	317_V	0.615	0.57
374_V	408_I	0.614	0.57
82_G	191_A	0.614	0.57
162_T	206_M	0.614	0.57
359_V	381_Q	0.614	0.57
299_P	305_P	0.613	0.57
44_V	83_V	0.612	0.57
33_V	318_M	0.611	0.57
43_L	65_Y	0.611	0.57
172_E	182_E	0.610	0.57
167_T	278_H	0.609	0.56
289_E	308_T	0.607	0.56
139_L	213_G	0.607	0.56
406_S	413_N	0.607	0.56
145_G	148_S	0.606	0.56
13_T	17_G	0.606	0.56
324_G	327_G	0.604	0.56
365_I	418_V	0.603	0.56
46_D	62_T	0.603	0.56
15_G	18_V	0.602	0.56
224_K	402_E	0.602	0.56
28_K	334_Q	0.602	0.56
21_I	311_V	0.601	0.55
22_I	37_V	0.601	0.55
400_T	412_L	0.600	0.55
107_L	112_G	0.600	0.55
228_I	248_L	0.600	0.55
264_Q	425_Y	0.599	0.55
20_K	53_V	0.599	0.55
206_M	223_V	0.598	0.55
110_V	207_A	0.597	0.55
370_S	400_T	0.597	0.55
285_Y	295_M	0.596	0.55
70_D	288_G	0.596	0.55
130_A	307_A	0.596	0.55
149_D	288_G	0.595	0.55
340_K	344_D	0.594	0.55
281_F	293_E	0.592	0.54
214_F	223_V	0.592	0.54
13_T	307_A	0.592	0.54
23_Q	57_K	0.592	0.54
113_S	117_A	0.592	0.54
25_H	292_G	0.591	0.54
112_G	116_L	0.591	0.54
41_K	59_V	0.590	0.54
400_T	405_F	0.590	0.54
200_L	220_L	0.589	0.54
165_I	186_L	0.588	0.54
363_S	395_I	0.588	0.54
268_L	272_H	0.586	0.54
281_F	295_M	0.585	0.53
182_E	186_L	0.585	0.53
11_L	60_L	0.580	0.53
203_A	220_L	0.580	0.53
226_K	262_S	0.580	0.53
83_V	107_L	0.578	0.53
357_D	361_S	0.578	0.53
9_L	68_I	0.577	0.52
364_K	371_E	0.577	0.52
294_T	297_Y	0.576	0.52
365_I	376_F	0.575	0.52
402_E	425_Y	0.575	0.52
128_F	324_G	0.575	0.52
364_K	415_L	0.574	0.52
90_L	94_L	0.574	0.52
262_S	425_Y	0.574	0.52
18_V	303_S	0.573	0.52
101_V	314_L	0.573	0.52
162_T	204_R	0.573	0.52
227_G	248_L	0.572	0.52
87_K	107_L	0.572	0.52
181_K	401_S	0.572	0.52
98_K	235_D	0.570	0.52
370_S	408_I	0.570	0.52
154_M	283_A	0.568	0.51
13_T	179_V	0.568	0.51
250_G	266_T	0.568	0.51
44_V	133_A	0.566	0.51
106_D	191_A	0.566	0.51
258_K	338_N	0.565	0.51
142_L	212_L	0.564	0.51
238_F	392_E	0.564	0.51
110_V	200_L	0.561	0.50
288_G	296_F	0.560	0.50
61_T	70_D	0.559	0.50
416_E	419_Q	0.558	0.50
152_T	289_E	0.557	0.50
51_R	56_P	0.556	0.50
379_I	395_I	0.556	0.50
24_D	290_A	0.554	0.50
128_F	212_L	0.552	0.49
72_D	98_K	0.552	0.49
65_Y	84_E	0.551	0.49
117_A	217_N	0.551	0.49
28_K	31_H	0.551	0.49
238_F	394_V	0.549	0.49
106_D	203_A	0.549	0.49
11_L	55_L	0.548	0.49
77_I	310_V	0.544	0.48
272_H	295_M	0.544	0.48
293_E	311_V	0.543	0.48
24_D	304_M	0.543	0.48
351_L	395_I	0.543	0.48
249_I	262_S	0.542	0.48
99_H	122_N	0.542	0.48
244_Y	269_P	0.541	0.48
119_A	122_N	0.541	0.48
106_D	280_E	0.541	0.48
172_E	178_E	0.539	0.48
406_S	424_T	0.539	0.48
200_L	204_R	0.539	0.48
167_T	299_P	0.539	0.48
76_V	98_K	0.539	0.48
162_T	195_S	0.538	0.48
76_V	89_Y	0.538	0.48
322_R	325_V	0.538	0.48
236_I	245_T	0.537	0.47
224_K	339_M	0.536	0.47
349_Q	402_E	0.536	0.47
260_E	340_K	0.536	0.47
146_L	149_D	0.535	0.47
35_C	322_R	0.535	0.47
421_V	424_T	0.534	0.47
45_K	191_A	0.534	0.47
389_E	411_N	0.531	0.47
370_S	376_F	0.531	0.47
358_E	417_V	0.530	0.47
249_I	264_Q	0.530	0.47
363_S	400_T	0.529	0.46
131_S	319_K	0.528	0.46
251_I	426_R	0.527	0.46
411_N	414_D	0.526	0.46
59_V	66_D	0.526	0.46
21_I	25_H	0.525	0.46
260_E	426_R	0.525	0.46
152_T	214_F	0.524	0.46
91_V	126_I	0.523	0.46
174_S	177_E	0.522	0.46
154_M	284_V	0.521	0.45
349_Q	403_A	0.521	0.45
267_L	342_P	0.521	0.45
79_V	103_A	0.521	0.45
46_D	418_V	0.520	0.45
123_G	271_H	0.519	0.45
27_D	124_C	0.519	0.45
57_K	414_D	0.518	0.45
355_V	381_Q	0.518	0.45
341_S	344_D	0.516	0.45
11_L	53_V	0.515	0.45
360_G	391_A	0.515	0.45
108_M	127_Y	0.514	0.45
272_H	275_S	0.514	0.45
127_Y	316_A	0.514	0.45
42_V	58_E	0.512	0.44
264_Q	342_P	0.512	0.44
110_V	204_R	0.512	0.44
385_K	420_E	0.512	0.44
357_D	375_S	0.510	0.44
124_C	294_T	0.509	0.44
405_F	420_E	0.509	0.44
277_V	281_F	0.508	0.44
39_I	58_E	0.508	0.44
41_K	44_V	0.508	0.44
64_V	80_I	0.506	0.44
226_K	249_I	0.506	0.44
142_L	351_L	0.505	0.43
135_G	167_T	0.504	0.43
152_T	365_I	0.504	0.43
310_V	314_L	0.504	0.43
112_G	119_A	0.503	0.43
8_L	77_I	0.502	0.43
78_E	86_T	0.501	0.43
43_L	46_D	0.500	0.43

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mtjA	3	0.9769	100	0.331	Contact Map
4pg7A	2	0.9192	100	0.354	Contact Map
2ejwA	2	0.7644	100	0.473	Contact Map
3do5A	2	0.709	100	0.479	Contact Map
1ebfA	2	0.7136	100	0.479	Contact Map
3ingA	2	0.6905	100	0.496	Contact Map
3c8mA	2	0.709	100	0.536	Contact Map
4xb1A	2	0.6952	100	0.577	Contact Map
3wycA	2	0.6905	100	0.804	Contact Map
3bioA	4	0.5958	100	0.814	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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