PPB4 - BACSU - GREMLIN Contacts

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PPB4 - Alkaline phosphatase 4

UniProt:	P19406	Sequences: MKKMSLFQNMKSKLLPIAAVSVLTAGIFAGAELQQTEKASAKKQDKAEIRNVIVMIGDGMGTPYIRAYRSMKNNGDTPNNPKLTEFDRNLTGMMMTHPDDPDYNITDSAAAGTALATGVKTYNNAIGVDKNGKKVKSVLEEAKQQGKSTGLVATSEINHATPAAYGAHNESRKNMDQIANSYMDDKIKGKHKIDVLLGGGKSYFNRKDRNLTKEFKQAGYSYVTTKQALKKNKDQQVLGLFADGGLAKALDRDSKTPSLKDMTVSAIDRLNQNKKGFFLMVEGSQIDWAAHDNDTVGAMSEVKDFEQAYKAAIEFAKKDKHTLVIATADHTTGGFTIGANGEKNWHAEPILSAKKTPEFMAKKISEGKPVKDVLARYANLKVTSEEIKSVEAAAQADKSKGASKAIIKIFNTRSNSGWTSTDHTGEEVPVYAYGPGKEKFRGLINNTDQANIIFKILKTGK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	461 (403)
Sequences:	1912 (1291)
Seq/√Len:	64.3

ECOLI - PPB
BACSU - PPB4 PPB3
HALSA - Q9HHP0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
209_R	214_E	5.029	1.00
225_T	228_A	4.265	1.00
210_N	213_K	4.059	1.00
247_A	256_T	3.858	1.00
310_K	314_E	3.587	1.00
226_K	230_K	3.375	1.00
148_S	273_N	3.267	1.00
264_V	311_A	3.264	1.00
226_K	261_D	3.147	1.00
136_K	144_Q	3.090	1.00
285_Q	288_W	3.048	1.00
98_P	110_A	2.802	1.00
157_I	196_L	2.719	1.00
158_N	175_M	2.718	1.00
166_G	182_Y	2.667	1.00
143_K	194_D	2.640	1.00
106_T	111_A	2.622	1.00
156_E	175_M	2.594	1.00
139_L	278_F	2.544	1.00
167_A	178_I	2.535	1.00
260_K	311_A	2.441	1.00
265_S	268_D	2.416	1.00
155_S	284_S	2.398	1.00
265_S	269_R	2.394	1.00
212_T	222_Y	2.372	1.00
94_M	430_V	2.342	1.00
260_K	307_Q	2.331	1.00
161_T	280_M	2.320	1.00
153_A	284_S	2.309	1.00
308_A	312_A	2.309	1.00
197_L	237_V	2.307	1.00
197_L	239_G	2.249	1.00
260_K	304_D	2.197	1.00
112_G	164_A	2.183	1.00
57_G	286_I	2.178	1.00
305_F	309_Y	2.174	1.00
283_G	305_F	2.128	1.00
252_R	258_S	2.043	1.00
137_S	140_E	2.022	1.00
249_A	258_S	2.012	1.00
304_D	307_Q	1.998	1.00
201_K	222_Y	1.985	1.00
249_A	304_D	1.975	1.00
68_Y	303_K	1.952	1.00
85_E	306_E	1.947	1.00
63_P	426_E	1.930	1.00
268_D	315_F	1.869	1.00
61_G	331_T	1.863	1.00
125_A	128_V	1.853	1.00
139_L	149_T	1.816	1.00
267_I	312_A	1.800	1.00
176_D	203_Y	1.793	1.00
180_N	184_D	1.793	1.00
84_T	310_K	1.789	1.00
68_Y	302_V	1.726	0.99
251_D	297_G	1.707	0.99
169_N	181_S	1.700	0.99
55_M	312_A	1.700	0.99
56_I	115_L	1.699	0.99
84_T	306_E	1.693	0.99
92_G	430_V	1.688	0.99
121_T	125_A	1.687	0.99
263_T	312_A	1.677	0.99
92_G	444_I	1.669	0.99
65_I	431_Y	1.665	0.99
311_A	314_E	1.653	0.99
55_M	305_F	1.641	0.99
98_P	123_N	1.631	0.99
180_N	209_R	1.590	0.99
127_G	164_A	1.585	0.99
325_I	440_F	1.584	0.99
53_I	312_A	1.572	0.99
61_G	328_A	1.571	0.99
117_T	127_G	1.565	0.99
140_E	168_H	1.565	0.99
72_K	81_P	1.563	0.99
294_D	297_G	1.557	0.99
126_I	163_A	1.553	0.99
266_A	279_L	1.537	0.99
141_E	450_A	1.535	0.99
122_Y	125_A	1.521	0.99
386_E	413_R	1.507	0.99
147_K	457_L	1.501	0.99
151_L	165_Y	1.491	0.98
138_V	450_A	1.480	0.98
138_V	453_I	1.469	0.98
263_T	281_V	1.464	0.98
301_E	304_D	1.448	0.98
99_D	122_Y	1.444	0.98
94_M	449_Q	1.444	0.98
49_I	456_I	1.443	0.98
158_N	179_A	1.437	0.98
430_V	444_I	1.429	0.98
249_A	252_R	1.428	0.98
64_Y	290_A	1.426	0.98
92_G	441_R	1.425	0.98
331_T	426_E	1.425	0.98
260_K	308_A	1.421	0.98
264_V	268_D	1.400	0.98
316_A	324_V	1.398	0.98
448_D	451_N	1.395	0.98
55_M	324_V	1.394	0.98
317_K	320_K	1.393	0.98
62_T	429_P	1.388	0.97
237_V	269_R	1.387	0.97
290_A	298_A	1.381	0.97
142_A	457_L	1.379	0.97
375_A	379_N	1.374	0.97
220_Y	236_Q	1.372	0.97
117_T	135_V	1.367	0.97
106_T	110_A	1.365	0.97
316_A	322_T	1.352	0.97
248_K	285_Q	1.351	0.97
94_M	444_I	1.334	0.97
126_I	169_N	1.334	0.97
316_A	433_Y	1.327	0.97
383_T	386_E	1.319	0.97
197_L	241_F	1.313	0.96
103_Y	123_N	1.295	0.96
115_L	449_Q	1.292	0.96
156_E	244_G	1.291	0.96
127_G	137_S	1.287	0.96
95_M	445_N	1.285	0.96
202_S	205_N	1.283	0.96
175_M	245_G	1.283	0.96
183_M	215_F	1.278	0.96
313_I	433_Y	1.276	0.96
72_K	306_E	1.275	0.96
52_V	457_L	1.274	0.96
116_A	165_Y	1.271	0.96
55_M	283_G	1.266	0.96
98_P	106_T	1.265	0.96
129_D	133_K	1.265	0.96
202_S	244_G	1.262	0.96
242_A	256_T	1.260	0.96
377_Y	381_K	1.257	0.95
95_M	443_L	1.256	0.95
159_H	245_G	1.249	0.95
99_D	130_K	1.243	0.95
61_G	426_E	1.243	0.95
112_G	116_A	1.243	0.95
156_E	245_G	1.240	0.95
150_G	279_L	1.236	0.95
430_V	449_Q	1.235	0.95
56_I	161_T	1.225	0.95
155_S	288_W	1.218	0.95
248_K	292_D	1.218	0.95
239_G	262_M	1.216	0.95
151_L	166_G	1.210	0.94
440_F	452_I	1.198	0.94
308_A	311_A	1.193	0.94
139_L	193_I	1.187	0.94
439_K	455_K	1.185	0.94
72_K	303_K	1.178	0.94
229_L	265_S	1.169	0.93
213_K	216_K	1.163	0.93
69_R	427_E	1.161	0.93
127_G	135_V	1.160	0.93
68_Y	83_L	1.154	0.93
194_D	236_Q	1.154	0.93
286_I	302_V	1.148	0.93
375_A	378_A	1.141	0.92
325_I	453_I	1.139	0.92
97_H	445_N	1.138	0.92
55_M	309_Y	1.137	0.92
106_T	123_N	1.137	0.92
448_D	452_I	1.134	0.92
215_F	238_L	1.125	0.92
313_I	324_V	1.123	0.92
246_L	262_M	1.122	0.92
159_H	288_W	1.120	0.92
174_N	177_Q	1.112	0.92
283_G	308_A	1.102	0.91
156_E	159_H	1.101	0.91
305_F	326_A	1.097	0.91
195_V	266_A	1.088	0.91
245_G	288_W	1.065	0.90
386_E	389_S	1.060	0.89
110_A	123_N	1.056	0.89
53_I	316_A	1.056	0.89
106_T	446_N	1.055	0.89
263_T	267_I	1.054	0.89
142_A	459_T	1.052	0.89
52_V	453_I	1.050	0.89
201_K	224_T	1.046	0.89
312_A	316_A	1.042	0.89
363_K	366_E	1.042	0.89
139_L	165_Y	1.039	0.88
54_V	278_F	1.039	0.88
57_G	327_T	1.038	0.88
242_A	247_A	1.037	0.88
224_T	228_A	1.034	0.88
60_M	65_I	1.033	0.88
116_A	127_G	1.029	0.88
245_G	285_Q	1.029	0.88
90_L	437_K	1.028	0.88
259_L	304_D	1.026	0.88
246_L	256_T	1.025	0.88
379_N	382_V	1.021	0.88
311_A	315_F	1.021	0.88
230_K	265_S	1.015	0.87
283_G	312_A	1.011	0.87
143_K	149_T	1.008	0.87
142_A	149_T	0.992	0.86
84_T	87_D	0.988	0.86
141_E	454_F	0.983	0.86
241_F	262_M	0.978	0.85
431_Y	443_L	0.975	0.85
88_R	433_Y	0.974	0.85
450_A	454_F	0.972	0.85
115_L	280_M	0.968	0.85
235_Q	272_Q	0.964	0.84
124_N	171_S	0.963	0.84
158_N	204_F	0.958	0.84
375_A	381_K	0.957	0.84
152_V	195_V	0.956	0.84
250_L	297_G	0.954	0.84
202_S	243_D	0.953	0.84
159_H	175_M	0.951	0.84
331_T	424_T	0.950	0.84
152_V	266_A	0.944	0.83
82_K	87_D	0.943	0.83
312_A	324_V	0.943	0.83
140_E	144_Q	0.938	0.83
84_T	313_I	0.937	0.83
136_K	141_E	0.937	0.83
444_I	448_D	0.936	0.83
82_K	86_F	0.936	0.83
158_N	245_G	0.933	0.82
284_S	288_W	0.929	0.82
250_L	356_T	0.922	0.82
71_M	303_K	0.921	0.82
250_L	296_V	0.918	0.81
80_N	83_L	0.917	0.81
66_R	70_S	0.914	0.81
318_K	321_H	0.913	0.81
316_A	320_K	0.909	0.81
260_K	264_V	0.909	0.81
248_K	289_A	0.908	0.81
122_Y	130_K	0.907	0.81
296_V	408_K	0.903	0.80
54_V	325_I	0.902	0.80
388_K	392_A	0.901	0.80
377_Y	382_V	0.898	0.80
222_Y	240_L	0.897	0.80
69_R	86_F	0.893	0.80
126_I	164_A	0.889	0.79
183_M	214_E	0.886	0.79
143_K	192_K	0.880	0.79
274_K	320_K	0.877	0.78
197_L	229_L	0.874	0.78
150_G	276_G	0.873	0.78
105_I	338_G	0.872	0.78
60_M	302_V	0.872	0.78
61_G	335_F	0.871	0.78
54_V	327_T	0.871	0.78
182_Y	215_F	0.864	0.77
324_V	433_Y	0.862	0.77
289_A	294_D	0.854	0.76
267_I	315_F	0.854	0.76
234_D	269_R	0.852	0.76
201_K	243_D	0.850	0.76
372_D	376_R	0.850	0.76
90_L	441_R	0.850	0.76
158_N	203_Y	0.850	0.76
213_K	217_Q	0.847	0.76
93_M	429_P	0.845	0.76
135_V	168_H	0.838	0.75
317_K	321_H	0.835	0.75
150_G	195_V	0.832	0.75
146_G	275_K	0.828	0.74
148_S	275_K	0.825	0.74
197_L	262_M	0.824	0.74
195_V	235_Q	0.824	0.74
148_S	194_D	0.823	0.74
57_G	60_M	0.823	0.74
304_D	308_A	0.818	0.73
175_M	244_G	0.818	0.73
151_L	278_F	0.817	0.73
317_K	433_Y	0.816	0.73
195_V	237_V	0.816	0.73
449_Q	453_I	0.816	0.73
66_R	337_I	0.814	0.73
306_E	310_K	0.813	0.73
143_K	191_H	0.810	0.73
67_A	299_M	0.808	0.72
137_S	168_H	0.808	0.72
381_K	387_I	0.806	0.72
157_I	182_Y	0.805	0.72
147_K	276_G	0.804	0.72
372_D	377_Y	0.802	0.72
111_A	446_N	0.802	0.72
212_T	224_T	0.801	0.72
55_M	281_V	0.801	0.72
227_Q	230_K	0.799	0.72
230_K	261_D	0.799	0.72
271_N	315_F	0.799	0.72
296_V	300_S	0.798	0.71
78_P	86_F	0.795	0.71
54_V	115_L	0.795	0.71
248_K	288_W	0.793	0.71
159_H	173_K	0.790	0.71
116_A	280_M	0.790	0.71
314_E	318_K	0.781	0.70
289_A	297_G	0.781	0.70
251_D	301_E	0.778	0.69
83_L	86_F	0.776	0.69
309_Y	326_A	0.776	0.69
109_A	126_I	0.776	0.69
303_K	306_E	0.773	0.69
71_M	300_S	0.770	0.69
197_L	223_V	0.768	0.69
307_Q	310_K	0.766	0.68
211_L	214_E	0.765	0.68
223_V	237_V	0.763	0.68
399_S	404_K	0.763	0.68
407_I	411_N	0.763	0.68
119_V	135_V	0.762	0.68
134_K	168_H	0.758	0.67
370_V	374_L	0.758	0.67
444_I	452_I	0.757	0.67
182_Y	196_L	0.756	0.67
57_G	328_A	0.756	0.67
314_E	317_K	0.755	0.67
74_N	81_P	0.755	0.67
85_E	88_R	0.754	0.67
281_V	308_A	0.752	0.67
74_N	78_P	0.749	0.67
376_R	379_N	0.749	0.67
61_G	98_P	0.748	0.66
212_T	238_L	0.748	0.66
65_I	429_P	0.746	0.66
206_R	210_N	0.745	0.66
303_K	307_Q	0.744	0.66
432_A	440_F	0.743	0.66
60_M	286_I	0.742	0.66
91_T	432_A	0.741	0.66
50_R	321_H	0.738	0.65
223_V	229_L	0.737	0.65
73_N	81_P	0.735	0.65
227_Q	255_K	0.734	0.65
55_M	147_K	0.733	0.65
323_L	437_K	0.733	0.65
229_L	239_G	0.732	0.65
378_A	381_K	0.732	0.65
94_M	325_I	0.731	0.65
96_T	428_V	0.730	0.65
212_T	240_L	0.730	0.65
142_A	147_K	0.730	0.65
156_E	285_Q	0.727	0.64
62_T	426_E	0.725	0.64
214_E	217_Q	0.721	0.64
85_E	431_Y	0.720	0.63
180_N	211_L	0.720	0.63
73_N	79_N	0.717	0.63
264_V	315_F	0.717	0.63
216_K	219_G	0.715	0.63
277_F	315_F	0.714	0.63
236_Q	272_Q	0.714	0.63
151_L	193_I	0.713	0.63
325_I	450_A	0.711	0.63
205_N	208_D	0.710	0.62
116_A	278_F	0.709	0.62
368_K	371_K	0.707	0.62
293_N	334_G	0.706	0.62
359_F	363_K	0.706	0.62
154_T	262_M	0.706	0.62
64_Y	331_T	0.705	0.62
62_T	93_M	0.704	0.62
154_T	285_Q	0.703	0.62
102_D	122_Y	0.703	0.62
367_G	371_K	0.702	0.62
78_P	84_T	0.700	0.61
382_V	386_E	0.698	0.61
434_G	437_K	0.698	0.61
348_E	372_D	0.698	0.61
197_L	279_L	0.697	0.61
229_L	256_T	0.697	0.61
387_I	391_E	0.696	0.61
334_G	338_G	0.696	0.61
105_I	123_N	0.695	0.61
60_M	327_T	0.694	0.61
222_Y	261_D	0.693	0.61
292_D	420_S	0.692	0.60
369_P	372_D	0.687	0.60
347_A	350_I	0.686	0.60
169_N	174_N	0.686	0.60
115_L	450_A	0.685	0.60
88_R	313_I	0.685	0.60
77_T	81_P	0.683	0.59
216_K	222_Y	0.682	0.59
411_N	418_W	0.679	0.59
318_K	433_Y	0.679	0.59
66_R	86_F	0.677	0.59
251_D	356_T	0.677	0.59
115_L	161_T	0.674	0.58
258_S	263_T	0.674	0.58
54_V	165_Y	0.674	0.58
113_T	121_T	0.673	0.58
371_K	378_A	0.672	0.58
212_T	216_K	0.671	0.58
283_G	286_I	0.670	0.58
175_M	203_Y	0.669	0.58
213_K	227_Q	0.665	0.57
229_L	255_K	0.662	0.57
110_A	171_S	0.661	0.57
234_D	237_V	0.661	0.57
264_V	310_K	0.660	0.57
55_M	326_A	0.657	0.56
120_K	445_N	0.654	0.56
382_V	409_I	0.653	0.56
154_T	246_L	0.652	0.56
71_M	299_M	0.652	0.56
232_N	237_V	0.651	0.56
140_E	157_I	0.649	0.56
193_I	196_L	0.649	0.56
251_D	294_D	0.647	0.55
82_K	85_E	0.647	0.55
49_I	147_K	0.647	0.55
370_V	373_V	0.646	0.55
241_F	257_P	0.646	0.55
195_V	279_L	0.645	0.55
184_D	209_R	0.645	0.55
89_N	309_Y	0.644	0.55
169_N	177_Q	0.643	0.55
293_N	414_S	0.642	0.55
85_E	309_Y	0.641	0.55
57_G	326_A	0.640	0.55
99_D	102_D	0.639	0.54
64_Y	298_A	0.638	0.54
56_I	280_M	0.638	0.54
78_P	83_L	0.635	0.54
179_A	204_F	0.634	0.54
148_S	272_Q	0.634	0.54
441_R	444_I	0.633	0.54
281_V	312_A	0.633	0.54
183_M	211_L	0.631	0.53
56_I	355_K	0.631	0.53
217_Q	227_Q	0.629	0.53
251_D	408_K	0.629	0.53
323_L	434_G	0.628	0.53
179_A	211_L	0.626	0.53
81_P	86_F	0.626	0.53
89_N	433_Y	0.626	0.53
147_K	275_K	0.622	0.52
419_T	424_T	0.622	0.52
112_G	165_Y	0.622	0.52
110_A	124_N	0.621	0.52
439_K	456_I	0.620	0.52
76_D	81_P	0.620	0.52
381_K	386_E	0.619	0.52
107_D	123_N	0.619	0.52
327_T	428_V	0.619	0.52
45_D	438_E	0.617	0.52
66_R	427_E	0.617	0.52
170_E	174_N	0.617	0.52
223_V	228_A	0.615	0.52
55_M	308_A	0.613	0.51
92_G	442_G	0.613	0.51
93_M	443_L	0.612	0.51
405_A	409_I	0.610	0.51
116_A	137_S	0.609	0.51
56_I	327_T	0.608	0.51
221_S	232_N	0.606	0.51
118_G	195_V	0.604	0.50
382_V	389_S	0.603	0.50
355_K	359_F	0.602	0.50
164_A	280_M	0.600	0.50
370_V	375_A	0.597	0.50
371_K	375_A	0.597	0.50
114_A	120_K	0.595	0.49
258_S	261_D	0.595	0.49
306_E	431_Y	0.593	0.49
384_S	387_I	0.592	0.49
204_F	240_L	0.592	0.49
56_I	165_Y	0.590	0.49
232_N	236_Q	0.590	0.49
359_F	362_K	0.589	0.49
258_S	289_A	0.587	0.48
375_A	382_V	0.586	0.48
71_M	296_V	0.586	0.48
225_T	255_K	0.586	0.48
113_T	301_E	0.586	0.48
180_N	214_E	0.584	0.48
75_G	300_S	0.583	0.48
113_T	450_A	0.582	0.48
232_N	269_R	0.581	0.48
361_A	364_I	0.581	0.48
197_L	269_R	0.580	0.48
113_T	127_G	0.579	0.47
111_A	115_L	0.579	0.47
78_P	82_K	0.577	0.47
371_K	412_T	0.576	0.47
368_K	372_D	0.576	0.47
206_R	209_R	0.576	0.47
277_F	316_A	0.575	0.47
313_I	321_H	0.575	0.47
159_H	285_Q	0.571	0.47
232_N	235_Q	0.570	0.46
290_A	325_I	0.569	0.46
374_L	378_A	0.568	0.46
382_V	387_I	0.566	0.46
283_G	309_Y	0.566	0.46
192_K	236_Q	0.566	0.46
112_G	450_A	0.565	0.46
183_M	238_L	0.565	0.46
246_L	255_K	0.565	0.46
400_K	403_S	0.564	0.46
66_R	69_R	0.563	0.46
325_I	430_V	0.561	0.45
297_G	409_I	0.560	0.45
74_N	77_T	0.559	0.45
327_T	430_V	0.559	0.45
165_Y	280_M	0.559	0.45
153_A	157_I	0.558	0.45
335_F	338_G	0.558	0.45
176_D	202_S	0.558	0.45
115_L	325_I	0.558	0.45
56_I	305_F	0.557	0.45
121_T	335_F	0.557	0.45
157_I	179_A	0.556	0.45
54_V	453_I	0.555	0.45
400_K	410_F	0.554	0.45
195_V	269_R	0.553	0.44
227_Q	231_K	0.552	0.44
62_T	65_I	0.551	0.44
191_H	236_Q	0.550	0.44
323_L	456_I	0.549	0.44
67_A	335_F	0.549	0.44
206_R	211_L	0.548	0.44
232_N	238_L	0.546	0.44
64_Y	67_A	0.544	0.43
385_E	388_K	0.543	0.43
228_A	401_G	0.543	0.43
121_T	124_N	0.542	0.43
227_Q	391_E	0.541	0.43
110_A	121_T	0.541	0.43
105_I	425_G	0.541	0.43
210_N	214_E	0.540	0.43
330_H	423_H	0.540	0.43
91_T	441_R	0.539	0.43
291_H	330_H	0.539	0.43
221_S	236_Q	0.538	0.43
56_I	116_A	0.538	0.43
372_D	375_A	0.537	0.43
381_K	384_S	0.536	0.43
152_V	279_L	0.535	0.42
385_E	389_S	0.535	0.42
163_A	178_I	0.531	0.42
353_A	356_T	0.530	0.42
323_L	440_F	0.530	0.42
277_F	417_G	0.529	0.42
95_M	427_E	0.528	0.42
105_I	413_R	0.527	0.41
160_A	172_R	0.527	0.41
56_I	112_G	0.526	0.41
160_A	330_H	0.525	0.41
438_E	455_K	0.525	0.41
328_A	428_V	0.525	0.41
229_L	241_F	0.524	0.41
362_K	365_S	0.524	0.41
229_L	242_A	0.523	0.41
206_R	214_E	0.522	0.41
313_I	317_K	0.522	0.41
268_D	274_K	0.522	0.41
138_V	454_F	0.521	0.41
434_G	440_F	0.520	0.41
296_V	353_A	0.520	0.41
233_K	314_E	0.520	0.41
63_P	337_I	0.519	0.41
73_N	77_T	0.517	0.40
267_I	316_A	0.517	0.40
139_L	166_G	0.517	0.40
141_E	145_Q	0.517	0.40
157_I	240_L	0.516	0.40
156_E	202_S	0.516	0.40
129_D	132_G	0.515	0.40
294_D	409_I	0.515	0.40
373_V	377_Y	0.514	0.40
231_K	234_D	0.513	0.40
51_N	69_R	0.512	0.40
53_I	239_G	0.511	0.40
210_N	403_S	0.510	0.40
337_I	425_G	0.510	0.40
258_S	304_D	0.510	0.40
351_L	354_K	0.509	0.39
291_H	423_H	0.509	0.39
106_T	114_A	0.508	0.39
72_K	76_D	0.508	0.39
51_N	195_V	0.507	0.39
183_M	218_A	0.506	0.39
142_A	145_Q	0.505	0.39
160_A	423_H	0.505	0.39
218_A	265_S	0.504	0.39
440_F	449_Q	0.504	0.39
149_T	193_I	0.504	0.39
439_K	452_I	0.503	0.39
127_G	166_G	0.503	0.39
80_N	85_E	0.502	0.39
381_K	389_S	0.502	0.39
42_K	325_I	0.502	0.39
225_T	256_T	0.501	0.39
79_N	82_K	0.500	0.38
136_K	140_E	0.500	0.38

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3e2dA	2	0.8764	100	0.148	Contact Map
1k7hA	2	0.9002	100	0.276	Contact Map
2x98A	4	0.8655	100	0.325	Contact Map
1zedA	2	0.9046	100	0.363	Contact Map
3wbhA	2	0.8742	100	0.365	Contact Map
3a52A	2	0.8633	100	0.379	Contact Map
3tg0A	2	0.833	100	0.514	Contact Map
2w5vA	2	0.7419	100	0.671	Contact Map
2mlyB	1	0.2798	100	0.79	Contact Map
3q3qA	2	0.8482	99.9	0.839	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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