SYT2 - BACSU - GREMLIN Contacts

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SYT2 - Threonine--tRNA ligase 2

UniProt:	P18256	Sequences: MSKHVHIQLPDGQIQEYPKGITIKEAAGSISSSLQKKAAAGQVNGKLVDLSFKLEEDAELSIVTLDSQEGLQVLRHTTAHVLAQAVKRLYGEVSLGVGPVILDGFYYDMKLGKSLASGDLEAIEKEMKNIINENLEIKRIEVSYEEAEELFAQKDERLKLEILKDIPRGEDITLYQQGEFVDLCRGPHLPSTGMIKAFKLTRVSGAYWRGDSKNEVLQRVYGVAFQKKKDLDAHLHMLEEAAKRDHRKLGKQLGLFMFSEEAPGMPFYLPKGQIVRNELERFSRELQTNAGYDEVRTPFMMNQRLWEQSGHWDHYRDNMYFSEVDDTRFAMKPMNCPGHMLIFKNSLYSYRDLPIRMAEFGQVHRHEYSGALNGMLRVRTFCQDDAHIFVREDQIESEIKEAIRLIDEVYRTFGFEYSVELSTRPEDSLGDDSLWEASERALARVLEELGLSYEINEGDGAFYGPKIDFHIKDALKRSHQCATIQLDFQMPEKFDLTYINELNEKVRPVVIHRAVFGSIDRFFGILIEHYGGAFPVWLAPIQVQIIPVSHVHLDYCRKVQAELKQAGIRAGIDERNEKLGYKIRESQVQKIPYVLVLGDHEEQENAVNVRRFGHQQNEHVPFQTFKDKLVKQVENRGM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	638 (624)
Sequences:	3591 (1644)
Seq/√Len:	65.8

ECOLI - SYT
BACSU - SYT2 SYT1
HALSA - SYT
SULSO - SYT

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
500_N	506_V	5.969	1.00
552_H	599_D	3.926	1.00
396_E	444_R	3.789	1.00
558_K	605_N	3.759	1.00
126_E	129_N	3.460	1.00
88_R	126_E	3.372	1.00
141_E	171_D	3.289	1.00
443_A	447_E	3.285	1.00
134_N	191_S	3.254	1.00
396_E	448_E	3.190	1.00
44_N	56_E	3.177	1.00
78_T	224_A	3.062	1.00
42_Q	61_S	2.985	1.00
254_G	346_S	2.965	1.00
140_I	176_Q	2.874	1.00
303_Q	307_E	2.861	1.00
495_D	507_R	2.852	1.00
295_V	342_I	2.836	1.00
23_I	41_G	2.831	1.00
492_E	507_R	2.728	1.00
148_E	164_K	2.728	1.00
38_A	62_I	2.724	1.00
110_K	215_E	2.690	1.00
149_E	152_A	2.646	1.00
527_I	534_F	2.614	1.00
560_Q	570_A	2.589	1.00
502_L	506_V	2.571	1.00
110_K	158_L	2.527	1.00
86_V	109_M	2.499	1.00
88_R	133_E	2.464	1.00
257_M	269_L	2.462	1.00
228_K	232_D	2.431	1.00
81_V	131_I	2.398	1.00
500_N	504_E	2.359	1.00
562_E	623_Q	2.307	1.00
81_V	195_I	2.304	1.00
43_V	58_A	2.291	1.00
42_Q	69_E	2.287	1.00
138_K	176_Q	2.215	1.00
424_R	428_S	2.213	1.00
148_E	160_L	2.166	1.00
77_T	137_I	2.157	1.00
431_D	434_L	2.133	1.00
575_R	585_E	2.115	1.00
595_L	607_V	2.110	1.00
416_E	472_K	2.094	1.00
227_K	230_D	2.092	1.00
81_V	130_I	2.089	1.00
304_R	307_E	2.084	1.00
546_I	579_L	2.083	1.00
599_D	603_Q	2.075	1.00
226_Q	230_D	2.061	1.00
84_Q	177_Q	2.053	1.00
425_P	460_G	2.051	1.00
77_T	189_L	2.039	1.00
541_I	571_G	2.032	1.00
447_E	453_Y	2.028	1.00
144_Y	167_P	2.013	1.00
559_V	622_F	1.996	1.00
286_L	290_A	1.984	1.00
286_L	408_E	1.972	1.00
176_Q	181_V	1.968	1.00
440_R	444_R	1.951	1.00
152_A	164_K	1.934	1.00
560_Q	572_I	1.928	1.00
254_G	269_L	1.918	1.00
551_V	599_D	1.885	1.00
25_E	28_G	1.881	1.00
545_I	560_Q	1.880	1.00
400_K	448_E	1.859	1.00
624_T	627_D	1.855	1.00
286_L	289_N	1.851	1.00
428_S	432_D	1.839	1.00
301_M	338_G	1.839	1.00
282_F	412_T	1.830	1.00
87_K	180_F	1.811	1.00
87_K	156_E	1.810	1.00
549_S	552_H	1.784	1.00
134_N	193_G	1.778	1.00
440_R	443_A	1.777	1.00
88_R	179_E	1.777	1.00
40_A	73_V	1.771	1.00
271_K	589_Q	1.766	1.00
61_S	67_S	1.749	1.00
429_L	489_Q	1.746	1.00
124_E	199_K	1.742	1.00
199_K	235_L	1.726	1.00
93_V	111_L	1.721	1.00
404_R	449_L	1.720	1.00
557_R	560_Q	1.708	0.99
234_H	238_L	1.700	0.99
75_R	223_V	1.696	0.99
149_E	153_Q	1.696	0.99
111_L	115_L	1.692	0.99
443_A	455_I	1.692	0.99
17_Y	21_I	1.689	0.99
278_E	281_R	1.687	0.99
568_I	633_V	1.683	0.99
340_M	510_V	1.677	0.99
82_L	123_I	1.651	0.99
48_V	52_F	1.649	0.99
17_Y	29_S	1.648	0.99
560_Q	564_K	1.645	0.99
190_P	194_M	1.644	0.99
548_V	579_L	1.637	0.99
33_S	37_K	1.622	0.99
71_L	75_R	1.621	0.99
554_D	557_R	1.612	0.99
88_R	129_N	1.611	0.99
282_F	408_E	1.605	0.99
38_A	50_L	1.600	0.99
158_L	215_E	1.582	0.99
558_K	562_E	1.578	0.99
536_V	629_L	1.572	0.99
201_T	238_L	1.561	0.99
271_K	571_G	1.560	0.99
275_V	523_F	1.555	0.99
84_Q	135_L	1.555	0.99
418_S	478_S	1.547	0.99
403_I	469_F	1.542	0.99
392_E	437_A	1.539	0.99
533_A	590_K	1.535	0.99
456_N	459_D	1.532	0.99
32_S	36_K	1.532	0.99
248_K	252_Q	1.516	0.99
536_V	632_Q	1.511	0.99
151_F	174_L	1.502	0.99
568_I	629_L	1.500	0.99
15_Q	29_S	1.493	0.99
74_L	226_Q	1.491	0.99
630_V	634_E	1.479	0.98
26_A	60_L	1.475	0.98
239_E	242_A	1.472	0.98
87_K	92_E	1.470	0.98
44_N	58_A	1.461	0.98
587_Q	590_K	1.457	0.98
211_D	214_N	1.449	0.98
145_E	149_E	1.446	0.98
446_L	467_I	1.441	0.98
563_L	626_K	1.436	0.98
24_K	28_G	1.435	0.98
125_K	128_K	1.435	0.98
299_F	364_H	1.431	0.98
31_S	37_K	1.416	0.98
600_H	603_Q	1.413	0.98
557_R	574_E	1.412	0.98
345_N	348_Y	1.410	0.98
136_E	191_S	1.407	0.98
595_L	625_F	1.405	0.98
586_S	594_V	1.402	0.98
545_I	556_C	1.399	0.98
262_A	265_M	1.394	0.98
174_L	181_V	1.392	0.98
470_H	478_S	1.384	0.98
26_A	54_L	1.381	0.98
33_S	36_K	1.380	0.98
27_A	62_I	1.375	0.98
587_Q	594_V	1.375	0.98
368_Y	371_A	1.374	0.98
103_D	237_M	1.371	0.97
30_I	34_L	1.367	0.97
596_V	608_N	1.366	0.97
399_I	467_I	1.365	0.97
165_D	209_R	1.359	0.97
280_E	296_R	1.354	0.97
314_H	427_D	1.350	0.97
205_G	216_V	1.348	0.97
140_I	146_E	1.348	0.97
627_D	631_K	1.339	0.97
137_I	177_Q	1.336	0.97
546_I	594_V	1.336	0.97
41_G	62_I	1.333	0.97
303_Q	328_R	1.333	0.97
8_Q	59_E	1.333	0.97
555_Y	597_L	1.322	0.97
249_L	253_L	1.321	0.97
23_I	48_V	1.321	0.97
271_K	541_I	1.306	0.97
544_Q	586_S	1.305	0.97
97_V	162_I	1.305	0.97
144_Y	168_R	1.299	0.97
161_E	209_R	1.298	0.96
95_L	156_E	1.297	0.96
142_V	174_L	1.288	0.96
561_A	565_Q	1.287	0.96
268_Y	523_F	1.286	0.96
150_L	181_V	1.284	0.96
562_E	605_N	1.280	0.96
129_N	133_E	1.276	0.96
543_V	629_L	1.276	0.96
552_H	602_E	1.274	0.96
307_E	313_D	1.270	0.96
94_S	110_K	1.267	0.96
65_L	71_L	1.261	0.96
116_A	120_L	1.260	0.96
47_L	63_V	1.258	0.96
497_T	505_K	1.258	0.96
143_S	146_E	1.256	0.96
499_I	505_K	1.247	0.96
348_Y	352_D	1.246	0.96
423_T	455_I	1.243	0.96
54_L	58_A	1.232	0.95
628_K	632_Q	1.230	0.95
71_L	74_L	1.230	0.95
201_T	223_V	1.229	0.95
626_K	630_V	1.226	0.95
8_Q	14_I	1.221	0.95
148_E	163_L	1.219	0.95
423_T	443_A	1.218	0.95
92_E	112_G	1.216	0.95
621_P	624_T	1.216	0.95
288_T	564_K	1.215	0.95
142_V	150_L	1.214	0.95
230_D	233_A	1.214	0.95
543_V	568_I	1.212	0.95
70_G	226_Q	1.211	0.95
146_E	149_E	1.210	0.95
544_Q	589_Q	1.209	0.95
243_K	531_G	1.204	0.95
18_P	21_I	1.203	0.95
167_P	170_E	1.203	0.95
52_F	173_T	1.202	0.95
395_I	486_L	1.196	0.94
557_R	572_I	1.193	0.94
381_F	518_S	1.187	0.94
274_I	569_R	1.186	0.94
541_I	544_Q	1.185	0.94
290_A	408_E	1.185	0.94
39_A	73_V	1.182	0.94
27_A	30_I	1.181	0.94
42_Q	47_L	1.178	0.94
52_F	139_R	1.177	0.94
283_S	409_V	1.177	0.94
562_E	626_K	1.175	0.94
593_Y	632_Q	1.172	0.94
204_S	216_V	1.169	0.94
135_L	192_T	1.162	0.94
362_Q	380_T	1.160	0.93
356_R	398_E	1.158	0.93
76_H	99_P	1.158	0.93
290_A	405_L	1.156	0.93
97_V	101_I	1.154	0.93
22_T	25_E	1.153	0.93
72_Q	100_V	1.150	0.93
95_L	109_M	1.149	0.93
283_S	287_Q	1.148	0.93
274_I	278_E	1.146	0.93
393_D	501_E	1.144	0.93
323_E	326_D	1.142	0.93
276_R	296_R	1.141	0.93
554_D	558_K	1.135	0.93
348_Y	355_I	1.135	0.93
558_K	561_A	1.134	0.93
548_V	580_G	1.133	0.93
254_G	257_M	1.132	0.93
340_M	496_L	1.128	0.93
581_Y	585_E	1.127	0.92
432_D	436_E	1.125	0.92
43_V	60_L	1.125	0.92
259_S	341_L	1.119	0.92
28_G	32_S	1.119	0.92
41_G	48_V	1.118	0.92
37_K	66_D	1.118	0.92
135_L	179_E	1.114	0.92
562_E	566_A	1.112	0.92
609_V	625_F	1.108	0.92
65_L	74_L	1.106	0.92
289_N	565_Q	1.105	0.92
346_S	352_D	1.104	0.92
76_H	80_H	1.104	0.92
404_R	408_E	1.103	0.92
566_A	630_V	1.103	0.92
611_R	614_H	1.101	0.92
533_A	612_F	1.092	0.91
136_E	193_G	1.091	0.91
137_I	189_L	1.090	0.91
166_I	169_G	1.089	0.91
239_E	243_K	1.088	0.91
407_D	411_R	1.087	0.91
620_V	625_F	1.085	0.91
101_I	106_Y	1.084	0.91
562_E	622_F	1.082	0.91
276_R	280_E	1.082	0.91
556_C	572_I	1.080	0.91
312_W	330_A	1.077	0.91
111_L	218_Q	1.077	0.91
553_L	574_E	1.072	0.90
400_K	449_L	1.072	0.90
133_E	179_E	1.071	0.90
257_M	345_N	1.071	0.90
545_I	559_V	1.070	0.90
139_R	173_T	1.067	0.90
281_R	285_E	1.066	0.90
259_S	269_L	1.065	0.90
550_H	553_L	1.062	0.90
23_I	60_L	1.061	0.90
240_E	243_K	1.061	0.90
620_V	628_K	1.059	0.90
74_L	78_T	1.059	0.90
434_L	489_Q	1.058	0.90
323_E	328_R	1.056	0.90
115_L	220_V	1.056	0.90
279_L	516_F	1.054	0.90
93_V	109_M	1.054	0.90
277_N	281_R	1.051	0.90
299_F	362_Q	1.051	0.90
428_S	436_E	1.050	0.90
229_K	232_D	1.048	0.89
233_A	236_H	1.044	0.89
65_L	226_Q	1.043	0.89
77_T	81_V	1.039	0.89
24_K	35_Q	1.039	0.89
340_M	389_F	1.039	0.89
23_I	62_I	1.033	0.89
295_V	339_H	1.031	0.89
166_I	172_I	1.028	0.89
471_I	481_C	1.027	0.88
8_Q	57_D	1.026	0.88
287_Q	360_F	1.025	0.88
595_L	609_V	1.024	0.88
562_E	565_Q	1.022	0.88
120_L	222_G	1.021	0.88
278_E	569_R	1.018	0.88
11_D	30_I	1.017	0.88
86_V	93_V	1.017	0.88
34_L	62_I	1.017	0.88
615_Q	618_E	1.017	0.88
314_H	429_L	1.013	0.88
43_V	54_L	1.013	0.88
262_A	301_M	1.011	0.88
420_E	470_H	1.009	0.88
81_V	137_I	1.007	0.87
96_G	156_E	1.007	0.87
44_N	59_E	1.007	0.87
163_L	172_I	1.006	0.87
388_I	402_A	1.006	0.87
279_L	413_F	1.003	0.87
61_S	69_E	1.002	0.87
43_V	52_F	0.996	0.87
303_Q	312_W	0.995	0.87
444_R	448_E	0.994	0.87
74_L	224_A	0.990	0.87
21_I	25_E	0.989	0.87
89_L	123_I	0.988	0.86
63_V	73_V	0.986	0.86
135_L	177_Q	0.986	0.86
378_V	381_F	0.984	0.86
419_V	451_L	0.984	0.86
43_V	48_V	0.984	0.86
227_K	232_D	0.980	0.86
547_P	556_C	0.978	0.86
28_G	35_Q	0.977	0.86
9_L	60_L	0.974	0.86
557_R	561_A	0.973	0.86
600_H	604_E	0.965	0.85
273_Q	296_R	0.963	0.85
21_I	54_L	0.955	0.85
124_E	128_K	0.950	0.84
159_K	182_D	0.949	0.84
134_N	192_T	0.948	0.84
578_K	581_Y	0.948	0.84
302_N	327_T	0.942	0.84
140_I	174_L	0.941	0.84
275_V	278_E	0.941	0.84
94_S	157_R	0.940	0.84
533_A	587_Q	0.936	0.83
229_K	233_A	0.935	0.83
295_V	357_M	0.933	0.83
306_W	338_G	0.933	0.83
117_S	121_E	0.933	0.83
31_S	34_L	0.932	0.83
284_R	294_E	0.930	0.83
75_R	224_A	0.924	0.83
71_L	226_Q	0.923	0.82
623_Q	627_D	0.922	0.82
363_V	516_F	0.922	0.82
191_S	194_M	0.921	0.82
555_Y	559_V	0.916	0.82
599_D	602_E	0.912	0.82
605_N	622_F	0.911	0.82
547_P	552_H	0.910	0.82
436_E	440_R	0.909	0.82
97_V	209_R	0.909	0.82
80_H	99_P	0.909	0.82
99_P	188_H	0.908	0.81
391_R	501_E	0.908	0.81
22_T	53_K	0.907	0.81
17_Y	26_A	0.906	0.81
441_A	486_L	0.906	0.81
40_A	63_V	0.905	0.81
20_G	53_K	0.905	0.81
277_N	280_E	0.902	0.81
545_I	597_L	0.896	0.81
536_V	633_V	0.896	0.81
80_H	188_H	0.895	0.81
90_Y	113_K	0.894	0.80
184_C	188_H	0.887	0.80
236_H	239_E	0.886	0.80
166_I	171_D	0.884	0.80
9_L	31_S	0.883	0.80
421_L	486_L	0.883	0.80
11_D	34_L	0.882	0.80
614_H	617_N	0.881	0.79
420_E	456_N	0.878	0.79
27_A	35_Q	0.878	0.79
357_M	386_A	0.877	0.79
63_V	67_S	0.876	0.79
76_H	188_H	0.876	0.79
418_S	454_E	0.874	0.79
620_V	624_T	0.873	0.79
490_M	493_K	0.873	0.79
97_V	156_E	0.870	0.79
9_L	13_Q	0.869	0.79
79_A	185_R	0.869	0.79
403_I	449_L	0.867	0.78
135_L	178_G	0.867	0.78
74_L	131_I	0.865	0.78
111_L	114_S	0.865	0.78
545_I	572_I	0.864	0.78
249_L	252_Q	0.864	0.78
87_K	93_V	0.864	0.78
27_A	31_S	0.863	0.78
543_V	595_L	0.862	0.78
283_S	360_F	0.861	0.78
109_M	115_L	0.860	0.78
163_L	166_I	0.857	0.78
42_Q	63_V	0.855	0.77
568_I	630_V	0.855	0.77
579_L	582_K	0.854	0.77
359_E	382_C	0.854	0.77
545_I	622_F	0.854	0.77
550_H	576_N	0.854	0.77
54_L	57_D	0.853	0.77
608_N	616_Q	0.852	0.77
265_M	380_T	0.850	0.77
544_Q	571_G	0.850	0.77
423_T	460_G	0.849	0.77
120_L	200_L	0.848	0.77
103_D	234_H	0.845	0.77
115_L	121_E	0.844	0.76
566_A	626_K	0.844	0.76
287_Q	358_A	0.843	0.76
376_L	524_G	0.843	0.76
403_I	467_I	0.842	0.76
75_R	226_Q	0.841	0.76
236_H	243_K	0.841	0.76
27_A	34_L	0.841	0.76
148_E	152_A	0.840	0.76
419_V	469_F	0.840	0.76
605_N	623_Q	0.837	0.76
112_G	215_E	0.835	0.76
533_A	613_G	0.834	0.76
473_D	477_R	0.834	0.76
290_A	404_R	0.833	0.76
235_L	238_L	0.832	0.75
308_Q	494_F	0.832	0.75
391_R	394_Q	0.831	0.75
397_S	401_E	0.831	0.75
278_E	633_V	0.830	0.75
23_I	26_A	0.829	0.75
287_Q	402_A	0.825	0.75
212_S	215_E	0.825	0.75
384_D	479_H	0.824	0.75
606_A	621_P	0.823	0.75
609_V	620_V	0.822	0.75
144_Y	148_E	0.822	0.75
547_P	572_I	0.820	0.74
161_E	214_N	0.820	0.74
322_S	325_D	0.819	0.74
577_E	585_E	0.818	0.74
555_Y	602_E	0.817	0.74
76_H	184_C	0.817	0.74
19_K	55_E	0.813	0.74
399_I	484_I	0.812	0.74
158_L	214_N	0.811	0.74
107_Y	159_K	0.811	0.74
402_A	511_I	0.810	0.73
74_L	189_L	0.808	0.73
212_S	368_Y	0.804	0.73
424_R	432_D	0.803	0.73
293_D	357_M	0.803	0.73
88_R	130_I	0.803	0.73
236_H	240_E	0.799	0.72
548_V	552_H	0.799	0.72
107_Y	182_D	0.799	0.72
415_F	488_F	0.799	0.72
23_I	50_L	0.798	0.72
459_D	468_D	0.798	0.72
268_Y	520_D	0.796	0.72
113_K	119_D	0.794	0.72
573_D	582_K	0.793	0.72
282_F	286_L	0.793	0.72
99_P	184_C	0.792	0.72
21_I	26_A	0.791	0.72
473_D	480_Q	0.789	0.71
255_L	527_I	0.789	0.71
304_R	308_Q	0.788	0.71
421_L	446_L	0.788	0.71
201_T	235_L	0.786	0.71
536_V	593_Y	0.785	0.71
151_F	163_L	0.784	0.71
79_A	100_V	0.784	0.71
359_E	363_V	0.782	0.71
80_H	98_G	0.782	0.71
258_F	266_P	0.782	0.71
17_Y	20_G	0.778	0.70
534_F	539_A	0.777	0.70
383_Q	514_A	0.777	0.70
384_D	473_D	0.776	0.70
52_F	55_E	0.776	0.70
46_K	52_F	0.775	0.70
9_L	34_L	0.775	0.70
40_A	47_L	0.773	0.70
80_H	184_C	0.773	0.70
439_E	457_E	0.772	0.70
423_T	456_N	0.772	0.70
616_Q	619_H	0.771	0.70
306_W	425_P	0.769	0.70
290_A	401_E	0.769	0.70
553_L	557_R	0.769	0.70
86_V	123_I	0.768	0.69
166_I	170_E	0.766	0.69
83_A	180_F	0.766	0.69
347_L	505_K	0.765	0.69
421_L	443_A	0.765	0.69
78_T	198_F	0.763	0.69
608_N	619_H	0.763	0.69
289_N	564_K	0.762	0.69
113_K	122_A	0.761	0.69
71_L	223_V	0.758	0.68
341_L	344_K	0.757	0.68
237_M	475_L	0.752	0.68
255_L	534_F	0.751	0.68
76_H	98_G	0.750	0.68
150_L	176_Q	0.750	0.68
98_G	186_G	0.746	0.67
436_E	439_E	0.746	0.67
30_I	33_S	0.745	0.67
625_F	629_L	0.744	0.67
84_Q	179_E	0.744	0.67
253_L	589_Q	0.742	0.67
301_M	330_A	0.742	0.67
588_V	612_F	0.741	0.67
293_D	355_I	0.740	0.67
556_C	597_L	0.740	0.67
65_L	70_G	0.739	0.66
253_L	533_A	0.738	0.66
547_P	579_L	0.737	0.66
206_A	216_V	0.735	0.66
96_G	217_L	0.734	0.66
130_I	133_E	0.733	0.66
344_K	496_L	0.732	0.66
119_D	122_A	0.731	0.66
34_L	64_T	0.731	0.66
249_L	590_K	0.730	0.66
543_V	570_A	0.729	0.65
498_Y	506_V	0.728	0.65
384_D	480_Q	0.726	0.65
409_V	514_A	0.726	0.65
514_A	518_S	0.725	0.65
406_I	415_F	0.725	0.65
17_Y	54_L	0.721	0.65
266_P	380_T	0.721	0.65
30_I	35_Q	0.721	0.65
32_S	35_Q	0.720	0.64
407_D	417_Y	0.719	0.64
422_S	456_N	0.717	0.64
593_Y	625_F	0.716	0.64
145_E	168_R	0.714	0.64
559_V	563_L	0.714	0.64
563_L	622_F	0.713	0.64
133_E	192_T	0.712	0.64
159_K	188_H	0.712	0.64
82_L	86_V	0.711	0.63
360_F	514_A	0.711	0.63
161_E	165_D	0.710	0.63
67_S	70_G	0.709	0.63
363_V	402_A	0.709	0.63
289_N	408_E	0.707	0.63
276_R	382_C	0.706	0.63
160_L	164_K	0.705	0.63
265_M	301_M	0.705	0.63
78_T	81_V	0.703	0.63
96_G	162_I	0.702	0.62
92_E	111_L	0.702	0.62
126_E	133_E	0.700	0.62
144_Y	170_E	0.700	0.62
86_V	115_L	0.700	0.62
286_L	412_T	0.699	0.62
34_L	38_A	0.698	0.62
66_D	230_D	0.698	0.62
344_K	495_D	0.697	0.62
321_F	330_A	0.697	0.62
65_L	75_R	0.697	0.62
303_Q	321_F	0.697	0.62
41_G	60_L	0.696	0.62
157_R	215_E	0.696	0.62
180_F	183_L	0.696	0.62
233_A	237_M	0.694	0.62
98_G	107_Y	0.694	0.62
356_R	401_E	0.694	0.62
622_F	626_K	0.693	0.61
347_L	499_I	0.693	0.61
128_K	132_N	0.693	0.61
250_G	256_F	0.693	0.61
144_Y	172_I	0.692	0.61
312_W	410_Y	0.691	0.61
306_W	460_G	0.691	0.61
55_E	58_A	0.690	0.61
115_L	156_E	0.690	0.61
631_K	634_E	0.689	0.61
571_G	591_I	0.688	0.61
182_D	188_H	0.687	0.61
568_I	626_K	0.687	0.61
473_D	479_H	0.686	0.61
110_K	157_R	0.686	0.61
83_A	107_Y	0.683	0.60
147_A	172_I	0.682	0.60
420_E	478_S	0.681	0.60
294_E	410_Y	0.680	0.60
98_G	188_H	0.678	0.60
547_P	553_L	0.678	0.60
315_Y	468_D	0.677	0.60
536_V	625_F	0.675	0.59
39_A	65_L	0.674	0.59
317_D	427_D	0.674	0.59
402_A	484_I	0.674	0.59
140_I	181_V	0.672	0.59
142_V	148_E	0.672	0.59
424_R	439_E	0.670	0.59
563_L	568_I	0.668	0.59
464_G	488_F	0.668	0.59
489_Q	492_E	0.667	0.59
469_F	482_A	0.665	0.58
158_L	216_V	0.665	0.58
103_D	223_V	0.663	0.58
98_G	182_D	0.663	0.58
397_S	400_K	0.663	0.58
37_K	64_T	0.663	0.58
283_S	516_F	0.663	0.58
320_Y	366_H	0.660	0.58
402_A	406_I	0.660	0.58
232_D	236_H	0.660	0.58
455_I	460_G	0.660	0.58
31_S	35_Q	0.659	0.58
398_E	401_E	0.658	0.58
617_N	620_V	0.658	0.58
363_V	382_C	0.657	0.57
549_S	599_D	0.656	0.57
175_Y	187_P	0.655	0.57
611_R	632_Q	0.655	0.57
438_S	488_F	0.655	0.57
434_L	492_E	0.653	0.57
9_L	35_Q	0.651	0.57
47_L	73_V	0.650	0.57
314_H	489_Q	0.650	0.57
161_E	208_W	0.650	0.57
364_H	410_Y	0.650	0.57
287_Q	516_F	0.648	0.56
150_L	174_L	0.648	0.56
423_T	459_D	0.647	0.56
76_H	107_Y	0.645	0.56
491_P	510_V	0.644	0.56
292_Y	402_A	0.644	0.56
384_D	525_I	0.642	0.56
291_G	564_K	0.642	0.56
107_Y	188_H	0.642	0.56
9_L	12_G	0.642	0.56
99_P	107_Y	0.641	0.56
32_S	37_K	0.641	0.56
212_S	216_V	0.641	0.56
406_I	469_F	0.640	0.55
9_L	20_G	0.639	0.55
270_P	357_M	0.639	0.55
536_V	568_I	0.638	0.55
121_E	125_K	0.638	0.55
131_I	193_G	0.638	0.55
259_S	267_F	0.637	0.55
97_V	106_Y	0.637	0.55
285_E	567_G	0.637	0.55
21_I	53_K	0.635	0.55
54_L	60_L	0.635	0.55
299_F	380_T	0.635	0.55
101_I	221_Y	0.635	0.55
286_L	405_L	0.635	0.55
84_Q	137_I	0.634	0.55
24_K	50_L	0.632	0.55
63_V	69_E	0.632	0.55
384_D	477_R	0.631	0.54
541_I	570_A	0.630	0.54
131_I	198_F	0.627	0.54
277_N	294_E	0.626	0.54
331_M	474_A	0.626	0.54
547_P	597_L	0.626	0.54
363_V	376_L	0.625	0.54
145_E	148_E	0.625	0.54
73_V	77_T	0.624	0.54
423_T	446_L	0.622	0.53
425_P	481_C	0.620	0.53
148_E	166_I	0.619	0.53
80_H	107_Y	0.618	0.53
99_P	159_K	0.617	0.53
115_L	218_Q	0.617	0.53
383_Q	518_S	0.615	0.53
330_A	338_G	0.615	0.53
429_L	493_K	0.614	0.52
101_I	209_R	0.614	0.52
101_I	162_I	0.614	0.52
74_L	223_V	0.613	0.52
20_G	55_E	0.613	0.52
125_K	229_K	0.612	0.52
525_I	529_H	0.612	0.52
145_E	169_G	0.612	0.52
559_V	562_E	0.612	0.52
606_A	619_H	0.611	0.52
339_H	488_F	0.611	0.52
426_E	458_G	0.611	0.52
587_Q	613_G	0.611	0.52
315_Y	318_N	0.610	0.52
523_F	527_I	0.610	0.52
627_D	630_V	0.610	0.52
122_A	125_K	0.609	0.52
549_S	576_N	0.608	0.52
593_Y	611_R	0.607	0.52
38_A	64_T	0.605	0.51
142_V	147_A	0.605	0.51
98_G	184_C	0.604	0.51
81_V	197_A	0.603	0.51
200_L	220_V	0.603	0.51
200_L	222_G	0.603	0.51
142_V	146_E	0.603	0.51
343_F	510_V	0.603	0.51
456_N	470_H	0.602	0.51
89_L	126_E	0.602	0.51
277_N	288_T	0.602	0.51
343_F	348_Y	0.600	0.51
49_D	187_P	0.599	0.51
12_G	34_L	0.597	0.50
321_F	490_M	0.596	0.50
84_Q	130_I	0.596	0.50
274_I	277_N	0.596	0.50
455_I	459_D	0.594	0.50
558_K	602_E	0.593	0.50
139_R	175_Y	0.593	0.50
392_E	506_V	0.593	0.50
95_L	151_F	0.592	0.50
393_D	437_A	0.592	0.50
629_L	633_V	0.592	0.50
596_V	619_H	0.591	0.50
308_Q	490_M	0.590	0.50
97_V	185_R	0.589	0.49
24_K	51_S	0.589	0.49
362_Q	382_C	0.588	0.49
159_K	184_C	0.587	0.49
140_I	150_L	0.585	0.49
253_L	534_F	0.585	0.49
446_L	453_Y	0.585	0.49
90_Y	119_D	0.583	0.49
607_V	625_F	0.582	0.49
15_Q	26_A	0.582	0.49
484_I	511_I	0.582	0.49
460_G	481_C	0.581	0.49
586_S	591_I	0.580	0.48
480_Q	525_I	0.580	0.48
564_K	570_A	0.579	0.48
197_A	228_K	0.579	0.48
13_Q	30_I	0.579	0.48
280_E	339_H	0.579	0.48
614_H	618_E	0.578	0.48
82_L	220_V	0.578	0.48
102_L	472_K	0.577	0.48
197_A	231_L	0.577	0.48
287_Q	363_V	0.576	0.48
355_I	391_R	0.575	0.48
78_T	195_I	0.574	0.48
386_A	490_M	0.574	0.48
433_S	436_E	0.573	0.48
13_Q	34_L	0.572	0.47
575_R	578_K	0.571	0.47
26_A	29_S	0.571	0.47
587_Q	610_R	0.571	0.47
544_Q	597_L	0.570	0.47
48_V	58_A	0.570	0.47
524_G	527_I	0.570	0.47
294_E	482_A	0.569	0.47
296_R	362_Q	0.568	0.47
76_H	159_K	0.567	0.47
80_H	159_K	0.567	0.47
274_I	288_T	0.567	0.47
233_A	476_K	0.566	0.47
30_I	62_I	0.565	0.47
300_M	329_F	0.565	0.47
364_H	380_T	0.563	0.46
80_H	186_G	0.562	0.46
29_S	32_S	0.562	0.46
110_K	216_V	0.561	0.46
15_Q	34_L	0.560	0.46
242_A	248_K	0.559	0.46
265_M	299_F	0.559	0.46
46_K	149_E	0.559	0.46
303_Q	330_A	0.558	0.46
294_E	360_F	0.558	0.46
480_Q	518_S	0.557	0.46
262_A	299_F	0.557	0.46
140_I	143_S	0.557	0.46
312_W	316_R	0.556	0.46
612_F	618_E	0.556	0.46
98_G	159_K	0.556	0.46
422_S	490_M	0.555	0.45
373_N	376_L	0.554	0.45
322_S	366_H	0.553	0.45
578_K	584_R	0.553	0.45
277_N	284_R	0.553	0.45
75_R	198_F	0.553	0.45
283_S	363_V	0.553	0.45
617_N	628_K	0.553	0.45
65_L	189_L	0.552	0.45
330_A	410_Y	0.552	0.45
425_P	455_I	0.552	0.45
90_Y	122_A	0.552	0.45
473_D	525_I	0.551	0.45
545_I	607_V	0.551	0.45
99_P	186_G	0.551	0.45
53_K	56_E	0.551	0.45
133_E	178_G	0.550	0.45
611_R	618_E	0.550	0.45
420_E	454_E	0.550	0.45
287_Q	291_G	0.549	0.45
363_V	494_F	0.547	0.45
587_Q	614_H	0.547	0.45
441_A	445_V	0.546	0.44
254_G	271_K	0.546	0.44
96_G	161_E	0.546	0.44
555_Y	606_A	0.545	0.44
342_I	488_F	0.545	0.44
125_K	129_N	0.544	0.44
566_A	627_D	0.544	0.44
597_L	607_V	0.544	0.44
383_Q	480_Q	0.544	0.44
46_K	56_E	0.543	0.44
559_V	566_A	0.542	0.44
413_F	522_F	0.542	0.44
68_Q	72_Q	0.542	0.44
27_A	41_G	0.542	0.44
287_Q	384_D	0.542	0.44
516_F	519_I	0.542	0.44
73_V	190_P	0.541	0.44
240_E	244_R	0.540	0.44
395_I	399_I	0.540	0.44
237_M	476_K	0.538	0.43
269_L	345_N	0.538	0.43
87_K	137_I	0.538	0.43
23_I	53_K	0.538	0.43
292_Y	513_R	0.537	0.43
9_L	21_I	0.537	0.43
13_Q	29_S	0.537	0.43
544_Q	591_I	0.537	0.43
9_L	33_S	0.537	0.43
395_I	441_A	0.537	0.43
280_E	360_F	0.537	0.43
117_S	218_Q	0.536	0.43
434_L	437_A	0.535	0.43
276_R	363_V	0.535	0.43
95_L	180_F	0.535	0.43
409_V	515_V	0.535	0.43
101_I	185_R	0.534	0.43
128_K	228_K	0.534	0.43
93_V	115_L	0.534	0.43
188_H	221_Y	0.534	0.43
280_E	519_I	0.533	0.43
253_L	591_I	0.533	0.43
142_V	160_L	0.532	0.43
486_L	511_I	0.532	0.43
283_S	358_A	0.532	0.43
240_E	531_G	0.532	0.43
403_I	471_I	0.531	0.43
363_V	519_I	0.531	0.43
543_V	597_L	0.530	0.43
78_T	223_V	0.529	0.42
284_R	360_F	0.528	0.42
162_I	165_D	0.527	0.42
479_H	482_A	0.526	0.42
136_E	192_T	0.526	0.42
21_I	29_S	0.526	0.42
422_S	470_H	0.525	0.42
410_Y	471_I	0.525	0.42
276_R	362_Q	0.525	0.42
84_Q	192_T	0.525	0.42
237_M	472_K	0.524	0.42
107_Y	184_C	0.523	0.42
49_D	52_F	0.523	0.42
23_I	40_A	0.522	0.42
611_R	617_N	0.522	0.42
301_M	471_I	0.521	0.42
477_R	480_Q	0.521	0.42
608_N	617_N	0.521	0.42
288_T	294_E	0.520	0.41
300_M	322_S	0.520	0.41
399_I	442_L	0.520	0.41
400_K	404_R	0.519	0.41
133_E	136_E	0.519	0.41
45_G	61_S	0.519	0.41
69_E	72_Q	0.519	0.41
406_I	515_V	0.519	0.41
339_H	389_F	0.518	0.41
415_F	430_G	0.517	0.41
428_S	460_G	0.517	0.41
212_S	371_A	0.517	0.41
408_E	412_T	0.516	0.41
71_L	230_D	0.515	0.41
623_Q	626_K	0.514	0.41
176_Q	180_F	0.514	0.41
211_D	215_E	0.514	0.41
253_L	539_A	0.514	0.41
306_W	423_T	0.513	0.41
318_N	368_Y	0.513	0.41
306_W	481_C	0.513	0.41
473_D	518_S	0.512	0.41
492_E	495_D	0.512	0.41
287_Q	514_A	0.511	0.40
536_V	595_L	0.509	0.40
443_A	457_E	0.509	0.40
159_K	221_Y	0.507	0.40
189_L	197_A	0.507	0.40
244_R	531_G	0.507	0.40
232_D	615_Q	0.507	0.40
467_I	488_F	0.506	0.40
262_A	382_C	0.506	0.40
360_F	519_I	0.506	0.40
84_Q	88_R	0.505	0.40
287_Q	386_A	0.504	0.40
430_G	473_D	0.503	0.40
254_G	348_Y	0.503	0.40
143_S	173_T	0.502	0.39
391_R	498_Y	0.501	0.39
137_I	179_E	0.500	0.39

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1qf6A	1	0.9937	100	0.344	Contact Map
1nyrA	2	0.9953	100	0.364	Contact Map
3uh0A	2	0.6207	100	0.654	Contact Map
4hwtA	2	0.6191	100	0.655	Contact Map
1evlA	2	0.6191	100	0.657	Contact Map
3a32A	2	0.6176	100	0.667	Contact Map
3qneA	2	0.6583	100	0.719	Contact Map
2j3lA	2	0.6332	100	0.723	Contact Map
1atiA	2	0.5627	100	0.724	Contact Map
2zt5A	2	0.5502	100	0.725	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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