GREMLIN Database
SYT2 - Threonine--tRNA ligase 2
UniProt: P18256 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 638 (624)
Sequences: 3591 (1644)
Seq/√Len: 65.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
500_N506_V5.9691.00
552_H599_D3.9261.00
396_E444_R3.7891.00
558_K605_N3.7591.00
126_E129_N3.4601.00
88_R126_E3.3721.00
141_E171_D3.2891.00
443_A447_E3.2851.00
134_N191_S3.2541.00
396_E448_E3.1901.00
44_N56_E3.1771.00
78_T224_A3.0621.00
42_Q61_S2.9851.00
254_G346_S2.9651.00
140_I176_Q2.8741.00
303_Q307_E2.8611.00
495_D507_R2.8521.00
295_V342_I2.8361.00
23_I41_G2.8311.00
492_E507_R2.7281.00
148_E164_K2.7281.00
38_A62_I2.7241.00
110_K215_E2.6901.00
149_E152_A2.6461.00
527_I534_F2.6141.00
560_Q570_A2.5891.00
502_L506_V2.5711.00
110_K158_L2.5271.00
86_V109_M2.4991.00
88_R133_E2.4641.00
257_M269_L2.4621.00
228_K232_D2.4311.00
81_V131_I2.3981.00
500_N504_E2.3591.00
562_E623_Q2.3071.00
81_V195_I2.3041.00
43_V58_A2.2911.00
42_Q69_E2.2871.00
138_K176_Q2.2151.00
424_R428_S2.2131.00
148_E160_L2.1661.00
77_T137_I2.1571.00
431_D434_L2.1331.00
575_R585_E2.1151.00
595_L607_V2.1101.00
416_E472_K2.0941.00
227_K230_D2.0921.00
81_V130_I2.0891.00
304_R307_E2.0841.00
546_I579_L2.0831.00
599_D603_Q2.0751.00
226_Q230_D2.0611.00
84_Q177_Q2.0531.00
425_P460_G2.0511.00
77_T189_L2.0391.00
541_I571_G2.0321.00
447_E453_Y2.0281.00
144_Y167_P2.0131.00
559_V622_F1.9961.00
286_L290_A1.9841.00
286_L408_E1.9721.00
176_Q181_V1.9681.00
440_R444_R1.9511.00
152_A164_K1.9341.00
560_Q572_I1.9281.00
254_G269_L1.9181.00
551_V599_D1.8851.00
25_E28_G1.8811.00
545_I560_Q1.8801.00
400_K448_E1.8591.00
624_T627_D1.8551.00
286_L289_N1.8511.00
428_S432_D1.8391.00
301_M338_G1.8391.00
282_F412_T1.8301.00
87_K180_F1.8111.00
87_K156_E1.8101.00
549_S552_H1.7841.00
134_N193_G1.7781.00
440_R443_A1.7771.00
88_R179_E1.7771.00
40_A73_V1.7711.00
271_K589_Q1.7661.00
61_S67_S1.7491.00
429_L489_Q1.7461.00
124_E199_K1.7421.00
199_K235_L1.7261.00
93_V111_L1.7211.00
404_R449_L1.7201.00
557_R560_Q1.7080.99
234_H238_L1.7000.99
75_R223_V1.6960.99
149_E153_Q1.6960.99
111_L115_L1.6920.99
443_A455_I1.6920.99
17_Y21_I1.6890.99
278_E281_R1.6870.99
568_I633_V1.6830.99
340_M510_V1.6770.99
82_L123_I1.6510.99
48_V52_F1.6490.99
17_Y29_S1.6480.99
560_Q564_K1.6450.99
190_P194_M1.6440.99
548_V579_L1.6370.99
33_S37_K1.6220.99
71_L75_R1.6210.99
554_D557_R1.6120.99
88_R129_N1.6110.99
282_F408_E1.6050.99
38_A50_L1.6000.99
158_L215_E1.5820.99
558_K562_E1.5780.99
536_V629_L1.5720.99
201_T238_L1.5610.99
271_K571_G1.5600.99
275_V523_F1.5550.99
84_Q135_L1.5550.99
418_S478_S1.5470.99
403_I469_F1.5420.99
392_E437_A1.5390.99
533_A590_K1.5350.99
456_N459_D1.5320.99
32_S36_K1.5320.99
248_K252_Q1.5160.99
536_V632_Q1.5110.99
151_F174_L1.5020.99
568_I629_L1.5000.99
15_Q29_S1.4930.99
74_L226_Q1.4910.99
630_V634_E1.4790.98
26_A60_L1.4750.98
239_E242_A1.4720.98
87_K92_E1.4700.98
44_N58_A1.4610.98
587_Q590_K1.4570.98
211_D214_N1.4490.98
145_E149_E1.4460.98
446_L467_I1.4410.98
563_L626_K1.4360.98
24_K28_G1.4350.98
125_K128_K1.4350.98
299_F364_H1.4310.98
31_S37_K1.4160.98
600_H603_Q1.4130.98
557_R574_E1.4120.98
345_N348_Y1.4100.98
136_E191_S1.4070.98
595_L625_F1.4050.98
586_S594_V1.4020.98
545_I556_C1.3990.98
262_A265_M1.3940.98
174_L181_V1.3920.98
470_H478_S1.3840.98
26_A54_L1.3810.98
33_S36_K1.3800.98
27_A62_I1.3750.98
587_Q594_V1.3750.98
368_Y371_A1.3740.98
103_D237_M1.3710.97
30_I34_L1.3670.97
596_V608_N1.3660.97
399_I467_I1.3650.97
165_D209_R1.3590.97
280_E296_R1.3540.97
314_H427_D1.3500.97
205_G216_V1.3480.97
140_I146_E1.3480.97
627_D631_K1.3390.97
137_I177_Q1.3360.97
546_I594_V1.3360.97
41_G62_I1.3330.97
303_Q328_R1.3330.97
8_Q59_E1.3330.97
555_Y597_L1.3220.97
249_L253_L1.3210.97
23_I48_V1.3210.97
271_K541_I1.3060.97
544_Q586_S1.3050.97
97_V162_I1.3050.97
144_Y168_R1.2990.97
161_E209_R1.2980.96
95_L156_E1.2970.96
142_V174_L1.2880.96
561_A565_Q1.2870.96
268_Y523_F1.2860.96
150_L181_V1.2840.96
562_E605_N1.2800.96
129_N133_E1.2760.96
543_V629_L1.2760.96
552_H602_E1.2740.96
307_E313_D1.2700.96
94_S110_K1.2670.96
65_L71_L1.2610.96
116_A120_L1.2600.96
47_L63_V1.2580.96
497_T505_K1.2580.96
143_S146_E1.2560.96
499_I505_K1.2470.96
348_Y352_D1.2460.96
423_T455_I1.2430.96
54_L58_A1.2320.95
628_K632_Q1.2300.95
71_L74_L1.2300.95
201_T223_V1.2290.95
626_K630_V1.2260.95
8_Q14_I1.2210.95
148_E163_L1.2190.95
423_T443_A1.2180.95
92_E112_G1.2160.95
621_P624_T1.2160.95
288_T564_K1.2150.95
142_V150_L1.2140.95
230_D233_A1.2140.95
543_V568_I1.2120.95
70_G226_Q1.2110.95
146_E149_E1.2100.95
544_Q589_Q1.2090.95
243_K531_G1.2040.95
18_P21_I1.2030.95
167_P170_E1.2030.95
52_F173_T1.2020.95
395_I486_L1.1960.94
557_R572_I1.1930.94
381_F518_S1.1870.94
274_I569_R1.1860.94
541_I544_Q1.1850.94
290_A408_E1.1850.94
39_A73_V1.1820.94
27_A30_I1.1810.94
42_Q47_L1.1780.94
52_F139_R1.1770.94
283_S409_V1.1770.94
562_E626_K1.1750.94
593_Y632_Q1.1720.94
204_S216_V1.1690.94
135_L192_T1.1620.94
362_Q380_T1.1600.93
356_R398_E1.1580.93
76_H99_P1.1580.93
290_A405_L1.1560.93
97_V101_I1.1540.93
22_T25_E1.1530.93
72_Q100_V1.1500.93
95_L109_M1.1490.93
283_S287_Q1.1480.93
274_I278_E1.1460.93
393_D501_E1.1440.93
323_E326_D1.1420.93
276_R296_R1.1410.93
554_D558_K1.1350.93
348_Y355_I1.1350.93
558_K561_A1.1340.93
548_V580_G1.1330.93
254_G257_M1.1320.93
340_M496_L1.1280.93
581_Y585_E1.1270.92
432_D436_E1.1250.92
43_V60_L1.1250.92
259_S341_L1.1190.92
28_G32_S1.1190.92
41_G48_V1.1180.92
37_K66_D1.1180.92
135_L179_E1.1140.92
562_E566_A1.1120.92
609_V625_F1.1080.92
65_L74_L1.1060.92
289_N565_Q1.1050.92
346_S352_D1.1040.92
76_H80_H1.1040.92
404_R408_E1.1030.92
566_A630_V1.1030.92
611_R614_H1.1010.92
533_A612_F1.0920.91
136_E193_G1.0910.91
137_I189_L1.0900.91
166_I169_G1.0890.91
239_E243_K1.0880.91
407_D411_R1.0870.91
620_V625_F1.0850.91
101_I106_Y1.0840.91
562_E622_F1.0820.91
276_R280_E1.0820.91
556_C572_I1.0800.91
312_W330_A1.0770.91
111_L218_Q1.0770.91
553_L574_E1.0720.90
400_K449_L1.0720.90
133_E179_E1.0710.90
257_M345_N1.0710.90
545_I559_V1.0700.90
139_R173_T1.0670.90
281_R285_E1.0660.90
259_S269_L1.0650.90
550_H553_L1.0620.90
23_I60_L1.0610.90
240_E243_K1.0610.90
620_V628_K1.0590.90
74_L78_T1.0590.90
434_L489_Q1.0580.90
323_E328_R1.0560.90
115_L220_V1.0560.90
279_L516_F1.0540.90
93_V109_M1.0540.90
277_N281_R1.0510.90
299_F362_Q1.0510.90
428_S436_E1.0500.90
229_K232_D1.0480.89
233_A236_H1.0440.89
65_L226_Q1.0430.89
77_T81_V1.0390.89
24_K35_Q1.0390.89
340_M389_F1.0390.89
23_I62_I1.0330.89
295_V339_H1.0310.89
166_I172_I1.0280.89
471_I481_C1.0270.88
8_Q57_D1.0260.88
287_Q360_F1.0250.88
595_L609_V1.0240.88
562_E565_Q1.0220.88
120_L222_G1.0210.88
278_E569_R1.0180.88
11_D30_I1.0170.88
86_V93_V1.0170.88
34_L62_I1.0170.88
615_Q618_E1.0170.88
314_H429_L1.0130.88
43_V54_L1.0130.88
262_A301_M1.0110.88
420_E470_H1.0090.88
81_V137_I1.0070.87
96_G156_E1.0070.87
44_N59_E1.0070.87
163_L172_I1.0060.87
388_I402_A1.0060.87
279_L413_F1.0030.87
61_S69_E1.0020.87
43_V52_F0.9960.87
303_Q312_W0.9950.87
444_R448_E0.9940.87
74_L224_A0.9900.87
21_I25_E0.9890.87
89_L123_I0.9880.86
63_V73_V0.9860.86
135_L177_Q0.9860.86
378_V381_F0.9840.86
419_V451_L0.9840.86
43_V48_V0.9840.86
227_K232_D0.9800.86
547_P556_C0.9780.86
28_G35_Q0.9770.86
9_L60_L0.9740.86
557_R561_A0.9730.86
600_H604_E0.9650.85
273_Q296_R0.9630.85
21_I54_L0.9550.85
124_E128_K0.9500.84
159_K182_D0.9490.84
134_N192_T0.9480.84
578_K581_Y0.9480.84
302_N327_T0.9420.84
140_I174_L0.9410.84
275_V278_E0.9410.84
94_S157_R0.9400.84
533_A587_Q0.9360.83
229_K233_A0.9350.83
295_V357_M0.9330.83
306_W338_G0.9330.83
117_S121_E0.9330.83
31_S34_L0.9320.83
284_R294_E0.9300.83
75_R224_A0.9240.83
71_L226_Q0.9230.82
623_Q627_D0.9220.82
363_V516_F0.9220.82
191_S194_M0.9210.82
555_Y559_V0.9160.82
599_D602_E0.9120.82
605_N622_F0.9110.82
547_P552_H0.9100.82
436_E440_R0.9090.82
97_V209_R0.9090.82
80_H99_P0.9090.82
99_P188_H0.9080.81
391_R501_E0.9080.81
22_T53_K0.9070.81
17_Y26_A0.9060.81
441_A486_L0.9060.81
40_A63_V0.9050.81
20_G53_K0.9050.81
277_N280_E0.9020.81
545_I597_L0.8960.81
536_V633_V0.8960.81
80_H188_H0.8950.81
90_Y113_K0.8940.80
184_C188_H0.8870.80
236_H239_E0.8860.80
166_I171_D0.8840.80
9_L31_S0.8830.80
421_L486_L0.8830.80
11_D34_L0.8820.80
614_H617_N0.8810.79
420_E456_N0.8780.79
27_A35_Q0.8780.79
357_M386_A0.8770.79
63_V67_S0.8760.79
76_H188_H0.8760.79
418_S454_E0.8740.79
620_V624_T0.8730.79
490_M493_K0.8730.79
97_V156_E0.8700.79
9_L13_Q0.8690.79
79_A185_R0.8690.79
403_I449_L0.8670.78
135_L178_G0.8670.78
74_L131_I0.8650.78
111_L114_S0.8650.78
545_I572_I0.8640.78
249_L252_Q0.8640.78
87_K93_V0.8640.78
27_A31_S0.8630.78
543_V595_L0.8620.78
283_S360_F0.8610.78
109_M115_L0.8600.78
163_L166_I0.8570.78
42_Q63_V0.8550.77
568_I630_V0.8550.77
579_L582_K0.8540.77
359_E382_C0.8540.77
545_I622_F0.8540.77
550_H576_N0.8540.77
54_L57_D0.8530.77
608_N616_Q0.8520.77
265_M380_T0.8500.77
544_Q571_G0.8500.77
423_T460_G0.8490.77
120_L200_L0.8480.77
103_D234_H0.8450.77
115_L121_E0.8440.76
566_A626_K0.8440.76
287_Q358_A0.8430.76
376_L524_G0.8430.76
403_I467_I0.8420.76
75_R226_Q0.8410.76
236_H243_K0.8410.76
27_A34_L0.8410.76
148_E152_A0.8400.76
419_V469_F0.8400.76
605_N623_Q0.8370.76
112_G215_E0.8350.76
533_A613_G0.8340.76
473_D477_R0.8340.76
290_A404_R0.8330.76
235_L238_L0.8320.75
308_Q494_F0.8320.75
391_R394_Q0.8310.75
397_S401_E0.8310.75
278_E633_V0.8300.75
23_I26_A0.8290.75
287_Q402_A0.8250.75
212_S215_E0.8250.75
384_D479_H0.8240.75
606_A621_P0.8230.75
609_V620_V0.8220.75
144_Y148_E0.8220.75
547_P572_I0.8200.74
161_E214_N0.8200.74
322_S325_D0.8190.74
577_E585_E0.8180.74
555_Y602_E0.8170.74
76_H184_C0.8170.74
19_K55_E0.8130.74
399_I484_I0.8120.74
158_L214_N0.8110.74
107_Y159_K0.8110.74
402_A511_I0.8100.73
74_L189_L0.8080.73
212_S368_Y0.8040.73
424_R432_D0.8030.73
293_D357_M0.8030.73
88_R130_I0.8030.73
236_H240_E0.7990.72
548_V552_H0.7990.72
107_Y182_D0.7990.72
415_F488_F0.7990.72
23_I50_L0.7980.72
459_D468_D0.7980.72
268_Y520_D0.7960.72
113_K119_D0.7940.72
573_D582_K0.7930.72
282_F286_L0.7930.72
99_P184_C0.7920.72
21_I26_A0.7910.72
473_D480_Q0.7890.71
255_L527_I0.7890.71
304_R308_Q0.7880.71
421_L446_L0.7880.71
201_T235_L0.7860.71
536_V593_Y0.7850.71
151_F163_L0.7840.71
79_A100_V0.7840.71
359_E363_V0.7820.71
80_H98_G0.7820.71
258_F266_P0.7820.71
17_Y20_G0.7780.70
534_F539_A0.7770.70
383_Q514_A0.7770.70
384_D473_D0.7760.70
52_F55_E0.7760.70
46_K52_F0.7750.70
9_L34_L0.7750.70
40_A47_L0.7730.70
80_H184_C0.7730.70
439_E457_E0.7720.70
423_T456_N0.7720.70
616_Q619_H0.7710.70
306_W425_P0.7690.70
290_A401_E0.7690.70
553_L557_R0.7690.70
86_V123_I0.7680.69
166_I170_E0.7660.69
83_A180_F0.7660.69
347_L505_K0.7650.69
421_L443_A0.7650.69
78_T198_F0.7630.69
608_N619_H0.7630.69
289_N564_K0.7620.69
113_K122_A0.7610.69
71_L223_V0.7580.68
341_L344_K0.7570.68
237_M475_L0.7520.68
255_L534_F0.7510.68
76_H98_G0.7500.68
150_L176_Q0.7500.68
98_G186_G0.7460.67
436_E439_E0.7460.67
30_I33_S0.7450.67
625_F629_L0.7440.67
84_Q179_E0.7440.67
253_L589_Q0.7420.67
301_M330_A0.7420.67
588_V612_F0.7410.67
293_D355_I0.7400.67
556_C597_L0.7400.67
65_L70_G0.7390.66
253_L533_A0.7380.66
547_P579_L0.7370.66
206_A216_V0.7350.66
96_G217_L0.7340.66
130_I133_E0.7330.66
344_K496_L0.7320.66
119_D122_A0.7310.66
34_L64_T0.7310.66
249_L590_K0.7300.66
543_V570_A0.7290.65
498_Y506_V0.7280.65
384_D480_Q0.7260.65
409_V514_A0.7260.65
514_A518_S0.7250.65
406_I415_F0.7250.65
17_Y54_L0.7210.65
266_P380_T0.7210.65
30_I35_Q0.7210.65
32_S35_Q0.7200.64
407_D417_Y0.7190.64
422_S456_N0.7170.64
593_Y625_F0.7160.64
145_E168_R0.7140.64
559_V563_L0.7140.64
563_L622_F0.7130.64
133_E192_T0.7120.64
159_K188_H0.7120.64
82_L86_V0.7110.63
360_F514_A0.7110.63
161_E165_D0.7100.63
67_S70_G0.7090.63
363_V402_A0.7090.63
289_N408_E0.7070.63
276_R382_C0.7060.63
160_L164_K0.7050.63
265_M301_M0.7050.63
78_T81_V0.7030.63
96_G162_I0.7020.62
92_E111_L0.7020.62
126_E133_E0.7000.62
144_Y170_E0.7000.62
86_V115_L0.7000.62
286_L412_T0.6990.62
34_L38_A0.6980.62
66_D230_D0.6980.62
344_K495_D0.6970.62
321_F330_A0.6970.62
65_L75_R0.6970.62
303_Q321_F0.6970.62
41_G60_L0.6960.62
157_R215_E0.6960.62
180_F183_L0.6960.62
233_A237_M0.6940.62
98_G107_Y0.6940.62
356_R401_E0.6940.62
622_F626_K0.6930.61
347_L499_I0.6930.61
128_K132_N0.6930.61
250_G256_F0.6930.61
144_Y172_I0.6920.61
312_W410_Y0.6910.61
306_W460_G0.6910.61
55_E58_A0.6900.61
115_L156_E0.6900.61
631_K634_E0.6890.61
571_G591_I0.6880.61
182_D188_H0.6870.61
568_I626_K0.6870.61
473_D479_H0.6860.61
110_K157_R0.6860.61
83_A107_Y0.6830.60
147_A172_I0.6820.60
420_E478_S0.6810.60
294_E410_Y0.6800.60
98_G188_H0.6780.60
547_P553_L0.6780.60
315_Y468_D0.6770.60
536_V625_F0.6750.59
39_A65_L0.6740.59
317_D427_D0.6740.59
402_A484_I0.6740.59
140_I181_V0.6720.59
142_V148_E0.6720.59
424_R439_E0.6700.59
563_L568_I0.6680.59
464_G488_F0.6680.59
489_Q492_E0.6670.59
469_F482_A0.6650.58
158_L216_V0.6650.58
103_D223_V0.6630.58
98_G182_D0.6630.58
397_S400_K0.6630.58
37_K64_T0.6630.58
283_S516_F0.6630.58
320_Y366_H0.6600.58
402_A406_I0.6600.58
232_D236_H0.6600.58
455_I460_G0.6600.58
31_S35_Q0.6590.58
398_E401_E0.6580.58
617_N620_V0.6580.58
363_V382_C0.6570.57
549_S599_D0.6560.57
175_Y187_P0.6550.57
611_R632_Q0.6550.57
438_S488_F0.6550.57
434_L492_E0.6530.57
9_L35_Q0.6510.57
47_L73_V0.6500.57
314_H489_Q0.6500.57
161_E208_W0.6500.57
364_H410_Y0.6500.57
287_Q516_F0.6480.56
150_L174_L0.6480.56
423_T459_D0.6470.56
76_H107_Y0.6450.56
491_P510_V0.6440.56
292_Y402_A0.6440.56
384_D525_I0.6420.56
291_G564_K0.6420.56
107_Y188_H0.6420.56
9_L12_G0.6420.56
99_P107_Y0.6410.56
32_S37_K0.6410.56
212_S216_V0.6410.56
406_I469_F0.6400.55
9_L20_G0.6390.55
270_P357_M0.6390.55
536_V568_I0.6380.55
121_E125_K0.6380.55
131_I193_G0.6380.55
259_S267_F0.6370.55
97_V106_Y0.6370.55
285_E567_G0.6370.55
21_I53_K0.6350.55
54_L60_L0.6350.55
299_F380_T0.6350.55
101_I221_Y0.6350.55
286_L405_L0.6350.55
84_Q137_I0.6340.55
24_K50_L0.6320.55
63_V69_E0.6320.55
384_D477_R0.6310.54
541_I570_A0.6300.54
131_I198_F0.6270.54
277_N294_E0.6260.54
331_M474_A0.6260.54
547_P597_L0.6260.54
363_V376_L0.6250.54
145_E148_E0.6250.54
73_V77_T0.6240.54
423_T446_L0.6220.53
425_P481_C0.6200.53
148_E166_I0.6190.53
80_H107_Y0.6180.53
99_P159_K0.6170.53
115_L218_Q0.6170.53
383_Q518_S0.6150.53
330_A338_G0.6150.53
429_L493_K0.6140.52
101_I209_R0.6140.52
101_I162_I0.6140.52
74_L223_V0.6130.52
20_G55_E0.6130.52
125_K229_K0.6120.52
525_I529_H0.6120.52
145_E169_G0.6120.52
559_V562_E0.6120.52
606_A619_H0.6110.52
339_H488_F0.6110.52
426_E458_G0.6110.52
587_Q613_G0.6110.52
315_Y318_N0.6100.52
523_F527_I0.6100.52
627_D630_V0.6100.52
122_A125_K0.6090.52
549_S576_N0.6080.52
593_Y611_R0.6070.52
38_A64_T0.6050.51
142_V147_A0.6050.51
98_G184_C0.6040.51
81_V197_A0.6030.51
200_L220_V0.6030.51
200_L222_G0.6030.51
142_V146_E0.6030.51
343_F510_V0.6030.51
456_N470_H0.6020.51
89_L126_E0.6020.51
277_N288_T0.6020.51
343_F348_Y0.6000.51
49_D187_P0.5990.51
12_G34_L0.5970.50
321_F490_M0.5960.50
84_Q130_I0.5960.50
274_I277_N0.5960.50
455_I459_D0.5940.50
558_K602_E0.5930.50
139_R175_Y0.5930.50
392_E506_V0.5930.50
95_L151_F0.5920.50
393_D437_A0.5920.50
629_L633_V0.5920.50
596_V619_H0.5910.50
308_Q490_M0.5900.50
97_V185_R0.5890.49
24_K51_S0.5890.49
362_Q382_C0.5880.49
159_K184_C0.5870.49
140_I150_L0.5850.49
253_L534_F0.5850.49
446_L453_Y0.5850.49
90_Y119_D0.5830.49
607_V625_F0.5820.49
15_Q26_A0.5820.49
484_I511_I0.5820.49
460_G481_C0.5810.49
586_S591_I0.5800.48
480_Q525_I0.5800.48
564_K570_A0.5790.48
197_A228_K0.5790.48
13_Q30_I0.5790.48
280_E339_H0.5790.48
614_H618_E0.5780.48
82_L220_V0.5780.48
102_L472_K0.5770.48
197_A231_L0.5770.48
287_Q363_V0.5760.48
355_I391_R0.5750.48
78_T195_I0.5740.48
386_A490_M0.5740.48
433_S436_E0.5730.48
13_Q34_L0.5720.47
575_R578_K0.5710.47
26_A29_S0.5710.47
587_Q610_R0.5710.47
544_Q597_L0.5700.47
48_V58_A0.5700.47
524_G527_I0.5700.47
294_E482_A0.5690.47
296_R362_Q0.5680.47
76_H159_K0.5670.47
80_H159_K0.5670.47
274_I288_T0.5670.47
233_A476_K0.5660.47
30_I62_I0.5650.47
300_M329_F0.5650.47
364_H380_T0.5630.46
80_H186_G0.5620.46
29_S32_S0.5620.46
110_K216_V0.5610.46
15_Q34_L0.5600.46
242_A248_K0.5590.46
265_M299_F0.5590.46
46_K149_E0.5590.46
303_Q330_A0.5580.46
294_E360_F0.5580.46
480_Q518_S0.5570.46
262_A299_F0.5570.46
140_I143_S0.5570.46
312_W316_R0.5560.46
612_F618_E0.5560.46
98_G159_K0.5560.46
422_S490_M0.5550.45
373_N376_L0.5540.45
322_S366_H0.5530.45
578_K584_R0.5530.45
277_N284_R0.5530.45
75_R198_F0.5530.45
283_S363_V0.5530.45
617_N628_K0.5530.45
65_L189_L0.5520.45
330_A410_Y0.5520.45
425_P455_I0.5520.45
90_Y122_A0.5520.45
473_D525_I0.5510.45
545_I607_V0.5510.45
99_P186_G0.5510.45
53_K56_E0.5510.45
133_E178_G0.5500.45
611_R618_E0.5500.45
420_E454_E0.5500.45
287_Q291_G0.5490.45
363_V494_F0.5470.45
587_Q614_H0.5470.45
441_A445_V0.5460.44
254_G271_K0.5460.44
96_G161_E0.5460.44
555_Y606_A0.5450.44
342_I488_F0.5450.44
125_K129_N0.5440.44
566_A627_D0.5440.44
597_L607_V0.5440.44
383_Q480_Q0.5440.44
46_K56_E0.5430.44
559_V566_A0.5420.44
413_F522_F0.5420.44
68_Q72_Q0.5420.44
27_A41_G0.5420.44
287_Q384_D0.5420.44
516_F519_I0.5420.44
73_V190_P0.5410.44
240_E244_R0.5400.44
395_I399_I0.5400.44
237_M476_K0.5380.43
269_L345_N0.5380.43
87_K137_I0.5380.43
23_I53_K0.5380.43
292_Y513_R0.5370.43
9_L21_I0.5370.43
13_Q29_S0.5370.43
544_Q591_I0.5370.43
9_L33_S0.5370.43
395_I441_A0.5370.43
280_E360_F0.5370.43
117_S218_Q0.5360.43
434_L437_A0.5350.43
276_R363_V0.5350.43
95_L180_F0.5350.43
409_V515_V0.5350.43
101_I185_R0.5340.43
128_K228_K0.5340.43
93_V115_L0.5340.43
188_H221_Y0.5340.43
280_E519_I0.5330.43
253_L591_I0.5330.43
142_V160_L0.5320.43
486_L511_I0.5320.43
283_S358_A0.5320.43
240_E531_G0.5320.43
403_I471_I0.5310.43
363_V519_I0.5310.43
543_V597_L0.5300.43
78_T223_V0.5290.42
284_R360_F0.5280.42
162_I165_D0.5270.42
479_H482_A0.5260.42
136_E192_T0.5260.42
21_I29_S0.5260.42
422_S470_H0.5250.42
410_Y471_I0.5250.42
276_R362_Q0.5250.42
84_Q192_T0.5250.42
237_M472_K0.5240.42
107_Y184_C0.5230.42
49_D52_F0.5230.42
23_I40_A0.5220.42
611_R617_N0.5220.42
301_M471_I0.5210.42
477_R480_Q0.5210.42
608_N617_N0.5210.42
288_T294_E0.5200.41
300_M322_S0.5200.41
399_I442_L0.5200.41
400_K404_R0.5190.41
133_E136_E0.5190.41
45_G61_S0.5190.41
69_E72_Q0.5190.41
406_I515_V0.5190.41
339_H389_F0.5180.41
415_F430_G0.5170.41
428_S460_G0.5170.41
212_S371_A0.5170.41
408_E412_T0.5160.41
71_L230_D0.5150.41
623_Q626_K0.5140.41
176_Q180_F0.5140.41
211_D215_E0.5140.41
253_L539_A0.5140.41
306_W423_T0.5130.41
318_N368_Y0.5130.41
306_W481_C0.5130.41
473_D518_S0.5120.41
492_E495_D0.5120.41
287_Q514_A0.5110.40
536_V595_L0.5090.40
443_A457_E0.5090.40
159_K221_Y0.5070.40
189_L197_A0.5070.40
244_R531_G0.5070.40
232_D615_Q0.5070.40
467_I488_F0.5060.40
262_A382_C0.5060.40
360_F519_I0.5060.40
84_Q88_R0.5050.40
287_Q386_A0.5040.40
430_G473_D0.5030.40
254_G348_Y0.5030.40
143_S173_T0.5020.39
391_R498_Y0.5010.39
137_I179_E0.5000.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1qf6A 1 0.9937 100 0.344 Contact Map
1nyrA 2 0.9953 100 0.364 Contact Map
3uh0A 2 0.6207 100 0.654 Contact Map
4hwtA 2 0.6191 100 0.655 Contact Map
1evlA 2 0.6191 100 0.657 Contact Map
3a32A 2 0.6176 100 0.667 Contact Map
3qneA 2 0.6583 100 0.719 Contact Map
2j3lA 2 0.6332 100 0.723 Contact Map
1atiA 2 0.5627 100 0.724 Contact Map
2zt5A 2 0.5502 100 0.725 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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