GREMLIN Database
SYT1 - Threonine--tRNA ligase 1
UniProt: P18255 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 643 (623)
Sequences: 3568 (1624)
Seq/√Len: 65.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
507_G513_H5.9891.00
560_H607_D4.1121.00
566_K613_G3.8271.00
398_K451_E3.8171.00
126_E129_K3.4601.00
88_R126_E3.4181.00
450_K454_D3.3411.00
134_N191_S3.2841.00
398_K455_E3.1951.00
44_N56_E3.1801.00
78_A224_A3.0811.00
42_K61_E3.0051.00
254_K348_D2.9611.00
140_K176_E2.9201.00
304_K308_E2.9071.00
296_V344_I2.8791.00
23_T41_G2.8751.00
502_D514_R2.8511.00
141_E171_T2.8281.00
499_E514_R2.8121.00
38_S62_I2.7601.00
148_K164_D2.7591.00
110_E215_Q2.7461.00
149_A152_A2.6951.00
534_I541_L2.6111.00
110_E158_L2.5751.00
568_Q578_V2.5721.00
509_D513_H2.5561.00
86_I109_V2.5251.00
257_A270_L2.4871.00
228_K232_E2.4721.00
88_R133_A2.4531.00
507_G511_K2.4391.00
81_L131_V2.4291.00
81_L195_I2.3351.00
43_L58_G2.3041.00
570_R631_D2.3001.00
138_V176_E2.2731.00
148_K160_L2.2461.00
42_K69_E2.2421.00
427_R435_Y2.2421.00
77_S137_I2.2061.00
603_L615_V2.1881.00
438_D441_M2.1681.00
227_K230_D2.1161.00
226_F230_D2.1081.00
553_I587_I2.1041.00
607_D611_E2.1011.00
583_R593_E2.0951.00
81_L130_I2.0891.00
84_Q177_Q2.0891.00
305_E308_E2.0801.00
77_S189_V2.0661.00
548_V579_E2.0481.00
428_D467_A2.0441.00
144_R167_P2.0151.00
454_D460_Y2.0131.00
567_V630_L1.9981.00
176_E181_F1.9801.00
287_K410_D1.9771.00
152_A164_D1.9711.00
287_K291_L1.9611.00
447_S451_E1.9531.00
568_Q580_V1.9481.00
254_K270_L1.9271.00
25_D28_A1.8951.00
552_V568_Q1.8941.00
287_K290_S1.8781.00
402_I455_E1.8711.00
556_S560_H1.8611.00
632_E635_K1.8561.00
435_Y439_D1.8451.00
87_K156_D1.8321.00
447_S450_K1.8241.00
302_G340_H1.8191.00
40_A73_I1.8151.00
87_K180_F1.8051.00
199_K235_L1.8051.00
283_Y414_D1.8041.00
61_E67_S1.7981.00
134_N193_G1.7881.00
272_K597_Q1.7881.00
124_E199_K1.7881.00
558_A607_D1.7551.00
93_V111_M1.7491.00
88_R179_E1.7481.00
406_R456_I1.7361.00
436_F496_L1.7260.99
75_R223_T1.7190.99
190_P194_K1.7170.99
565_K568_Q1.7140.99
234_H238_L1.7120.99
149_A153_E1.7100.99
342_M517_V1.7100.99
279_V282_R1.7030.99
450_K462_E1.7000.99
568_Q572_Q1.6980.99
17_F21_T1.6950.99
111_M115_I1.6920.99
82_L123_I1.6640.99
48_I52_T1.6640.99
33_G37_K1.6420.99
17_F29_S1.6270.99
158_L215_Q1.6170.99
88_R129_K1.6120.99
566_K570_R1.6120.99
283_Y410_D1.6110.99
562_D565_K1.6090.99
555_V587_I1.6050.99
144_R168_E1.5940.99
71_L75_R1.5850.99
394_P444_K1.5820.99
276_I530_V1.5810.99
463_A466_E1.5690.99
272_K579_E1.5570.99
543_T637_A1.5570.99
38_S50_L1.5560.99
576_L637_A1.5520.99
84_Q135_L1.5500.99
421_T485_E1.5420.99
201_L238_L1.5370.99
540_A598_K1.5300.99
405_V476_V1.5260.99
15_K29_S1.5250.99
211_D214_N1.5150.99
239_E242_K1.5120.99
248_K252_E1.5080.99
32_P36_K1.5060.99
571_L634_V1.4930.99
74_M226_F1.4880.98
44_N58_G1.4770.98
595_Q598_K1.4770.98
87_K92_D1.4660.98
26_I60_V1.4540.98
125_K128_K1.4490.98
565_K582_S1.4470.98
151_F174_I1.4430.98
608_Q611_E1.4380.98
24_E28_A1.4350.98
453_M474_L1.4330.98
543_T640_E1.4270.98
174_I181_F1.4260.98
103_N237_M1.4230.98
145_E149_A1.4170.98
603_L633_F1.4150.98
300_V366_H1.4140.98
477_Q485_E1.4060.98
31_S37_K1.4050.98
347_Q350_H1.4010.98
401_F474_L1.3960.98
552_V564_A1.3950.98
165_A209_R1.3910.98
594_A602_M1.3880.98
26_I54_I1.3870.98
136_P191_S1.3860.98
604_V616_N1.3850.98
205_G216_M1.3820.98
315_H434_K1.3760.97
281_E297_Y1.3750.97
635_K639_A1.3740.97
140_K146_E1.3730.97
553_I602_M1.3670.97
263_G266_L1.3660.97
23_T48_I1.3630.97
137_I177_Q1.3610.97
27_A62_I1.3580.97
370_M373_A1.3570.97
595_Q602_M1.3560.97
563_Y605_V1.3520.97
30_I34_L1.3500.97
41_G62_I1.3480.97
33_G36_K1.3470.97
551_Q594_A1.3350.97
8_T59_T1.3310.97
95_F156_D1.3210.97
570_R613_G1.3140.97
161_E209_R1.3120.97
54_I58_G1.3110.97
504_T512_Q1.3100.97
560_H610_A1.3090.97
97_V162_L1.3080.97
272_K548_V1.3050.96
308_E314_D1.3000.96
94_K110_E1.2990.96
142_V174_I1.2930.96
569_E573_C1.2890.96
150_R181_F1.2890.96
550_F637_A1.2820.96
269_W530_V1.2800.96
249_L253_L1.2690.96
426_Y450_K1.2640.96
129_K133_A1.2610.96
143_S146_E1.2600.96
506_I512_Q1.2570.96
350_H354_E1.2550.96
47_E63_I1.2540.96
116_T120_L1.2520.96
92_D112_D1.2480.95
201_L223_T1.2410.95
39_L73_I1.2360.95
289_I572_Q1.2350.95
22_T25_D1.2340.95
65_E71_L1.2330.95
426_Y462_E1.2330.95
230_D233_E1.2310.95
167_P170_E1.2300.95
70_G226_F1.2300.95
18_A21_T1.2280.95
243_E538_K1.2240.95
284_I411_V1.2210.95
148_K163_L1.2200.95
71_L74_M1.2180.95
551_Q597_Q1.2140.95
204_A216_M1.2120.95
42_K47_E1.2090.95
8_T14_V1.2060.95
275_T577_R1.2050.94
146_E149_A1.2050.94
550_F576_L1.2040.94
52_T139_R1.2030.94
629_S632_E1.1980.94
142_V150_R1.1940.94
52_T173_S1.1910.94
383_M525_T1.1880.94
275_T279_V1.1860.94
291_L407_L1.1850.94
548_V551_Q1.1850.94
574_E638_V1.1810.94
358_R400_E1.1770.94
291_L410_D1.1720.94
397_I493_L1.1710.94
304_K330_T1.1680.94
76_H99_P1.1560.93
350_H357_I1.1530.93
566_K569_E1.1510.93
565_K580_V1.1500.93
570_R634_V1.1490.93
364_T382_G1.1470.93
636_K640_E1.1470.93
28_A32_P1.1460.93
37_K66_G1.1460.93
290_S573_C1.1450.93
589_Y593_E1.1420.93
95_F109_V1.1420.93
97_V101_I1.1390.93
135_L179_E1.1370.93
277_R297_Y1.1360.93
133_A179_E1.1350.93
555_V588_G1.1330.92
284_I288_E1.1320.92
27_A30_I1.1320.92
342_M503_L1.1300.92
619_K622_E1.1290.92
562_D566_K1.1250.92
135_L192_T1.1250.92
254_K257_A1.1250.92
41_G48_I1.1230.92
617_V633_F1.1220.92
628_I633_F1.1150.92
570_R574_E1.1130.92
43_L60_V1.1120.92
72_Q100_V1.1100.92
8_T57_D1.1070.92
76_H80_H1.1070.92
166_I172_V1.1050.91
101_I106_Y1.1020.91
111_M218_Q1.1020.91
540_A620_Y1.1000.91
435_Y443_N1.1000.91
136_P193_G1.0980.91
439_D443_N1.0980.91
277_R281_E1.0980.91
282_R286_D1.0970.91
395_D508_E1.0920.91
65_E74_M1.0910.91
406_R410_D1.0870.91
278_R282_R1.0850.91
93_V109_V1.0800.91
139_R173_S1.0790.90
634_V638_V1.0790.90
257_A347_Q1.0790.90
402_I456_I1.0780.90
422_F458_H1.0770.90
137_I189_V1.0760.90
570_R630_L1.0740.90
61_E69_E1.0730.90
441_M496_L1.0720.90
233_E236_R1.0720.90
229_A232_E1.0720.90
409_Q413_E1.0680.90
348_D354_E1.0650.90
564_A580_V1.0640.90
478_V488_L1.0600.90
280_I523_V1.0600.90
120_L222_G1.0580.90
240_E243_E1.0570.90
23_T62_I1.0550.89
561_L582_S1.0530.89
74_M78_A1.0510.89
565_K569_E1.0490.89
65_E226_F1.0490.89
239_E243_E1.0480.89
313_W332_V1.0470.89
23_T60_V1.0440.89
570_R573_C1.0400.89
552_V567_V1.0370.89
342_M391_F1.0370.89
276_I279_V1.0360.89
300_V364_T1.0360.89
623_Q626_E1.0340.89
44_N59_T1.0300.88
263_G302_G1.0300.88
135_L177_Q1.0280.88
86_I93_V1.0280.88
315_H436_F1.0270.88
628_I636_K1.0270.88
77_S81_L1.0260.88
163_L172_V1.0260.88
24_E35_K1.0260.88
557_P561_L1.0250.88
115_I220_V1.0210.88
296_V341_H1.0200.88
280_I415_F1.0190.88
96_G156_D1.0190.88
43_L52_T1.0180.88
279_V577_R1.0140.88
43_L54_I1.0100.87
288_E362_L1.0050.87
423_R477_Q1.0040.87
63_I73_I1.0020.87
7_I26_I1.0010.87
43_L48_I1.0000.87
390_I404_T1.0000.87
304_K313_W0.9910.86
601_Y640_E0.9890.86
74_M224_A0.9880.86
393_R508_E0.9880.86
81_L137_I0.9860.86
380_V383_M0.9860.86
227_K232_E0.9830.86
21_T25_D0.9830.86
11_D30_I0.9750.85
34_L62_I0.9740.85
557_P584_D0.9730.85
89_I123_I0.9710.85
71_L226_F0.9660.85
608_Q612_N0.9650.85
296_V359_I0.9630.85
236_R239_E0.9630.85
603_L617_V0.9620.85
554_P564_A0.9550.84
451_E455_E0.9550.84
140_K174_I0.9520.84
229_A233_E0.9520.84
124_E128_K0.9520.84
94_K157_D0.9520.84
7_I60_V0.9510.84
134_N192_T0.9510.84
117_P121_P0.9430.83
586_K589_Y0.9420.83
285_V295_H0.9420.83
274_A297_Y0.9420.83
631_D635_K0.9400.83
303_S329_E0.9400.83
159_K182_D0.9380.83
90_Y113_E0.9360.83
28_A35_K0.9290.83
9_F60_V0.9290.83
448_M493_L0.9290.83
443_N447_S0.9280.82
22_T53_P0.9260.82
97_V209_R0.9250.82
27_A35_K0.9230.82
20_G53_P0.9220.82
554_P560_H0.9190.82
540_A595_Q0.9180.82
307_Y340_H0.9170.82
278_R281_E0.9170.82
613_G630_L0.9160.82
63_I67_S0.9110.81
75_R224_A0.9090.81
27_A31_S0.9090.81
80_H188_H0.9080.81
40_A63_I0.9070.81
365_M523_V0.9070.81
17_F26_I0.9050.81
80_H99_P0.9040.81
628_I632_E0.9040.81
552_V580_V0.9040.81
166_I169_G0.9020.81
99_P188_H0.9010.81
31_S34_L0.8960.80
622_E625_S0.8960.80
587_I590_K0.8920.80
76_H188_H0.8870.80
497_L500_R0.8840.79
97_V156_D0.8820.79
552_V605_V0.8820.79
21_T54_I0.8820.79
563_Y567_V0.8810.79
324_M328_N0.8810.79
191_S194_K0.8800.79
163_L166_I0.8790.79
423_R463_A0.8780.79
135_L178_G0.8770.79
109_V115_I0.8770.79
111_M114_A0.8760.79
550_F603_L0.8750.79
184_C188_H0.8750.79
9_F31_S0.8740.78
607_D610_A0.8730.78
23_T26_I0.8710.78
87_K93_V0.8690.78
112_D215_Q0.8670.78
359_I388_A0.8630.78
480_T484_K0.8630.78
148_K152_A0.8630.78
235_L238_L0.8620.78
284_I362_L0.8620.78
266_L382_G0.8590.77
54_I57_D0.8590.77
236_R243_E0.8570.77
540_A621_G0.8570.77
617_V628_I0.8550.77
421_T461_Y0.8550.77
166_I170_E0.8540.77
120_L200_L0.8540.77
11_D34_L0.8530.77
21_T26_I0.8520.77
378_Q531_A0.8500.77
424_L493_L0.8490.76
74_M131_V0.8490.76
405_V456_I0.8490.76
262_V268_L0.8480.76
19_K55_N0.8480.76
212_S215_Q0.8460.76
613_G631_D0.8440.76
42_K63_I0.8430.76
161_E214_N0.8420.76
361_E384_T0.8410.76
551_Q579_E0.8390.76
291_L406_R0.8390.76
144_R148_K0.8380.76
574_E634_V0.8370.75
393_R396_Q0.8370.75
249_L252_E0.8370.75
115_I121_P0.8360.75
426_Y467_A0.8350.75
466_E475_D0.8340.75
260_Q343_M0.8330.75
288_E360_A0.8320.75
405_V474_L0.8300.75
212_S370_M0.8300.75
158_L214_N0.8290.75
413_E418_S0.8250.74
76_H184_C0.8250.74
561_L565_K0.8240.74
288_E404_T0.8240.74
79_A185_R0.8240.74
294_E359_I0.8230.74
9_F13_A0.8230.74
258_N267_P0.8230.74
554_P580_V0.8220.74
401_F491_V0.8200.74
74_M189_V0.8190.74
446_Q464_E0.8190.74
309_T501_F0.8180.74
236_R240_E0.8180.74
75_R226_F0.8180.74
543_T601_Y0.8180.74
581_D590_K0.8170.74
107_Y159_K0.8140.73
103_N234_H0.8130.73
166_I171_T0.8130.73
614_A629_S0.8120.73
88_R130_I0.8100.73
417_L495_F0.8100.73
616_N624_N0.8090.73
386_N486_E0.8070.73
585_E593_E0.8070.73
576_L638_V0.8050.73
269_W527_E0.8040.72
418_S479_K0.8030.72
305_E309_T0.8020.72
113_E122_K0.7990.72
86_I123_I0.7990.72
83_A180_F0.7980.72
107_Y182_D0.7970.72
624_N627_T0.7970.72
386_N480_T0.7930.71
201_L235_L0.7900.71
7_I58_G0.7890.71
99_P184_C0.7890.71
541_L546_A0.7880.71
23_T50_L0.7860.71
361_E365_M0.7850.71
255_L541_L0.7850.71
480_T487_T0.7840.71
46_K52_T0.7830.70
253_L540_A0.7820.70
151_F163_L0.7810.70
427_R439_D0.7810.70
552_V630_L0.7790.70
321_F327_D0.7790.70
79_A100_V0.7790.70
399_D403_R0.7770.70
424_L450_K0.7770.70
596_M620_Y0.7760.70
27_A34_L0.7760.70
255_L534_I0.7750.70
262_V343_M0.7750.70
426_Y463_A0.7750.70
80_H98_G0.7750.70
80_H184_C0.7750.70
404_T518_I0.7740.70
422_F476_V0.7740.70
385_L521_G0.7710.69
563_Y610_A0.7690.69
343_M346_K0.7680.69
290_S572_Q0.7680.69
307_Y428_D0.7670.69
564_A605_V0.7630.68
346_K502_D0.7630.68
424_L453_M0.7630.68
349_I512_Q0.7620.68
291_L403_R0.7620.68
52_T55_N0.7610.68
283_Y287_K0.7570.68
616_N627_T0.7540.68
206_A216_M0.7530.67
443_N446_Q0.7520.67
78_A198_F0.7510.67
411_V521_G0.7490.67
17_F20_G0.7480.67
161_E165_A0.7460.67
160_L164_D0.7450.67
9_F34_L0.7450.67
30_I33_G0.7450.67
150_R176_E0.7440.67
40_A47_E0.7430.66
76_H98_G0.7420.66
633_F637_A0.7400.66
92_D111_M0.7400.66
17_F54_I0.7400.66
84_Q179_E0.7390.66
253_L597_Q0.7380.66
550_F578_V0.7380.66
130_I133_A0.7360.66
294_E357_I0.7360.66
302_G332_V0.7350.66
98_G186_G0.7330.65
601_Y633_F0.7330.65
98_G107_Y0.7320.65
113_E119_D0.7310.65
96_G217_L0.7300.65
267_P382_G0.7240.64
249_L598_K0.7240.64
237_M482_I0.7240.64
119_D122_K0.7240.64
71_L223_T0.7210.64
386_N487_T0.7200.64
67_S70_G0.7200.64
145_E168_E0.7190.64
521_G525_T0.7180.64
147_A172_V0.7180.64
567_V571_L0.7170.64
82_L86_I0.7150.63
34_L64_T0.7130.63
290_S410_D0.7130.63
277_R384_T0.7120.63
349_I506_I0.7110.63
346_K503_L0.7100.63
543_T633_F0.7090.63
159_K188_H0.7090.63
408_I417_L0.7080.63
78_A81_L0.7070.63
321_F368_Y0.7070.63
86_I115_I0.7060.62
362_L521_G0.7020.62
133_A192_T0.7020.62
480_T486_E0.7020.62
233_E237_M0.7020.62
128_K132_N0.7010.62
96_G162_L0.7010.62
543_T576_L0.7010.62
66_G230_D0.7010.62
7_I17_F0.7010.62
126_E133_A0.6990.62
287_K414_D0.6960.61
318_E434_K0.6960.61
34_L38_S0.6940.61
630_L634_V0.6930.61
30_I35_K0.6930.61
365_M404_T0.6930.61
99_P107_Y0.6910.61
266_L302_G0.6900.61
576_L634_V0.6890.61
144_R172_V0.6890.61
180_F183_L0.6880.60
32_P35_K0.6870.60
175_Y187_V0.6870.60
115_I156_D0.6860.60
579_E599_I0.6850.60
425_S463_A0.6840.60
65_E75_R0.6840.60
554_P561_L0.6830.60
110_E157_D0.6830.60
555_V560_H0.6810.60
250_G256_F0.6800.60
496_L499_E0.6800.60
63_I69_E0.6800.60
182_D188_H0.6800.60
37_K64_T0.6800.60
83_A107_Y0.6790.59
554_P587_I0.6780.59
471_G495_F0.6780.59
625_S628_I0.6770.59
571_L630_L0.6760.59
41_G60_V0.6760.59
144_R170_E0.6750.59
423_R485_E0.6750.59
404_T491_V0.6740.59
427_R446_Q0.6730.59
304_K322_P0.6710.59
55_N58_G0.6710.59
142_V148_K0.6690.58
39_L65_E0.6690.58
103_N223_T0.6680.58
399_D402_I0.6680.58
358_R403_R0.6660.58
98_G188_H0.6660.58
322_P332_V0.6660.58
150_R174_I0.6630.58
365_M384_T0.6630.58
260_Q270_L0.6610.57
98_G182_D0.6600.57
307_Y467_A0.6600.57
409_Q420_Y0.6590.57
295_H412_Y0.6590.57
441_M499_E0.6580.57
271_P359_I0.6580.57
400_E403_R0.6580.57
288_E523_V0.6580.57
101_I221_Y0.6540.57
293_Y404_T0.6540.57
313_W412_Y0.6530.56
157_D215_Q0.6520.56
140_K181_F0.6520.56
408_I476_V0.6520.56
161_E208_W0.6510.56
571_L576_L0.6500.56
554_P605_V0.6500.56
139_R175_Y0.6490.56
426_Y466_E0.6480.56
316_Y319_G0.6470.56
436_F500_R0.6470.56
158_L216_M0.6460.56
556_S607_D0.6450.56
292_G572_Q0.6430.55
445_A495_F0.6430.55
257_A260_Q0.6420.55
212_S216_M0.6420.55
31_S35_K0.6400.55
84_Q137_I0.6390.55
463_A477_Q0.6360.55
386_N532_F0.6360.55
101_I209_R0.6360.55
462_E467_A0.6350.54
287_K407_L0.6350.54
97_V106_Y0.6350.54
144_R169_G0.6350.54
162_L165_A0.6340.54
200_L222_G0.6340.54
47_E73_I0.6330.54
614_A627_T0.6310.54
65_E70_G0.6310.54
300_V382_G0.6310.54
232_E236_R0.6310.54
491_V518_I0.6310.54
76_H107_Y0.6300.54
101_I162_L0.6300.54
115_I218_Q0.6290.54
84_Q130_I0.6280.54
7_I21_T0.6280.54
316_Y475_D0.6280.54
200_L220_V0.6270.53
24_E50_L0.6270.53
107_Y188_H0.6260.53
386_N484_K0.6250.53
365_M378_Q0.6250.53
78_A195_I0.6250.53
9_F35_K0.6240.53
54_I60_V0.6240.53
74_M223_T0.6240.53
345_Y517_V0.6220.53
131_V193_G0.6220.53
278_R295_H0.6220.53
286_D575_G0.6220.53
404_T408_I0.6220.53
595_Q621_G0.6210.53
81_L197_E0.6210.53
532_F536_E0.6210.53
341_H495_F0.6190.53
102_E479_K0.6190.53
9_F12_G0.6180.52
385_L525_T0.6180.52
38_S64_T0.6180.52
284_I523_V0.6180.52
425_S497_L0.6170.52
281_E341_H0.6160.52
366_H412_Y0.6150.52
467_A488_L0.6150.52
99_P159_K0.6150.52
242_K248_K0.6140.52
324_M330_T0.6130.52
95_F151_F0.6130.52
426_Y453_M0.6130.52
530_V534_I0.6120.52
121_P125_K0.6120.52
498_P517_V0.6120.52
49_D187_V0.6110.52
462_E466_E0.6100.51
73_I77_S0.6100.51
333_L481_A0.6090.51
364_T384_T0.6080.51
142_V146_E0.6080.51
567_V570_R0.6070.51
122_K125_K0.6070.51
531_A534_I0.6060.51
125_K229_A0.6040.51
556_S584_D0.6040.51
425_S477_Q0.6030.51
476_V489_S0.6020.51
142_V147_A0.6010.50
80_H107_Y0.6000.50
253_L541_L0.5980.50
131_V198_F0.5980.50
254_K272_K0.5980.50
323_P368_Y0.5970.50
32_P37_K0.5970.50
433_E465_G0.5960.50
140_K150_R0.5960.50
548_V578_V0.5960.50
315_H496_L0.5950.50
20_G55_N0.5950.50
278_R289_I0.5940.50
145_E148_K0.5940.50
260_Q303_S0.5940.50
165_A169_G0.5940.50
601_Y619_K0.5940.50
604_V627_T0.5920.49
82_L220_V0.5910.49
98_G184_C0.5910.49
332_V340_H0.5900.49
615_V633_F0.5890.49
9_F20_G0.5880.49
428_D488_L0.5860.49
21_T29_S0.5850.49
567_V574_E0.5840.48
288_E292_G0.5830.48
563_Y614_A0.5820.48
345_Y350_H0.5820.48
89_I126_E0.5820.48
583_R586_K0.5820.48
566_K610_A0.5810.48
76_H159_K0.5810.48
125_K129_K0.5800.48
395_D444_K0.5790.48
197_E228_K0.5790.48
523_V526_M0.5790.48
253_L599_I0.5780.48
275_T278_R0.5780.48
26_I29_S0.5770.48
128_K228_K0.5760.48
440_E443_N0.5740.47
594_A599_I0.5740.47
21_T53_P0.5740.47
97_V185_R0.5730.47
232_E623_Q0.5730.47
80_H186_G0.5720.47
620_Y626_E0.5720.47
635_K638_V0.5710.47
73_I190_P0.5710.47
288_E365_M0.5700.47
168_E172_V0.5680.47
80_H159_K0.5670.46
551_Q605_V0.5670.46
53_P56_E0.5670.46
159_K184_C0.5660.46
75_R198_F0.5640.46
295_H362_L0.5640.46
309_T497_L0.5630.46
48_I58_G0.5620.46
161_E166_I0.5610.46
625_S636_K0.5610.46
278_R285_V0.5610.46
551_Q599_I0.5610.46
110_E216_M0.5600.46
366_H382_G0.5600.46
233_E483_G0.5600.46
240_E244_R0.5590.46
595_Q618_R0.5590.46
98_G159_K0.5590.46
117_P218_Q0.5590.46
275_T289_I0.5590.46
15_K34_L0.5590.46
197_E231_L0.5570.45
15_K26_I0.5550.45
266_L300_V0.5550.45
619_K626_E0.5550.45
237_M483_G0.5550.45
322_P497_L0.5540.45
605_V615_V0.5540.45
313_W317_Q0.5530.45
385_L487_T0.5520.45
240_E538_K0.5520.45
78_A223_T0.5520.45
90_Y119_D0.5520.45
99_P186_G0.5510.45
423_R461_Y0.5510.45
95_F180_F0.5510.45
619_K640_E0.5510.45
24_E51_R0.5500.44
375_S378_Q0.5500.44
493_L518_I0.5490.44
9_F21_T0.5490.44
622_E626_E0.5490.44
9_F33_G0.5490.44
586_K592_R0.5490.44
136_P192_T0.5490.44
357_I393_R0.5480.44
572_Q578_V0.5480.44
145_E169_G0.5470.44
448_M452_A0.5470.44
176_E180_F0.5460.44
140_K143_S0.5460.44
45_G61_E0.5460.44
263_G300_V0.5450.44
96_G161_E0.5450.44
388_A497_L0.5450.44
13_A30_I0.5440.44
93_V115_I0.5440.44
616_N625_S0.5430.44
304_K332_V0.5430.44
397_I401_F0.5430.44
487_T525_T0.5430.44
344_I495_F0.5420.44
295_H489_S0.5410.43
288_E386_N0.5410.43
308_E330_T0.5400.43
284_I365_M0.5390.43
365_M526_M0.5390.43
393_R505_Y0.5390.43
90_Y122_K0.5370.43
211_D215_Q0.5370.43
487_T532_F0.5370.43
293_Y520_R0.5370.43
23_T53_P0.5370.43
301_L323_P0.5370.43
13_A29_S0.5360.43
46_K149_A0.5360.43
148_K166_I0.5360.43
13_A34_L0.5360.43
332_V412_Y0.5350.43
412_Y478_V0.5350.43
27_A41_G0.5340.43
277_R365_M0.5340.43
397_I448_M0.5330.43
212_S373_A0.5330.43
12_G34_L0.5330.43
297_Y364_T0.5330.43
441_M444_K0.5320.42
281_E526_M0.5320.42
133_A178_G0.5320.42
270_L347_Q0.5320.42
484_K487_T0.5310.42
29_S32_P0.5310.42
84_Q192_T0.5300.42
365_M501_F0.5300.42
65_E189_V0.5300.42
71_L230_D0.5280.42
453_M460_Y0.5280.42
480_T532_F0.5280.42
394_P513_H0.5280.42
550_F605_V0.5270.42
68_E72_Q0.5260.42
84_Q88_R0.5250.42
188_H221_Y0.5250.42
450_K464_E0.5250.42
7_I54_I0.5230.41
405_V478_V0.5210.41
237_M479_K0.5210.41
426_Y446_Q0.5200.41
284_I360_A0.5200.41
411_V522_V0.5200.41
478_V485_E0.5190.41
408_I522_V0.5190.41
87_K137_I0.5180.41
415_F529_F0.5180.41
30_I62_I0.5180.41
505_Y513_H0.5160.41
417_L437_D0.5160.41
289_I295_H0.5150.40
257_A268_L0.5150.40
148_K165_A0.5150.40
244_R538_K0.5150.40
49_D52_T0.5140.40
543_T603_L0.5140.40
410_D414_D0.5120.40
574_E635_K0.5110.40
107_Y184_C0.5090.40
486_E489_S0.5090.40
550_F633_F0.5090.40
402_I406_R0.5080.40
301_L331_L0.5070.40
288_E388_A0.5070.40
405_V424_L0.5060.39
552_V615_V0.5060.39
631_D634_V0.5060.39
421_T477_Q0.5060.39
101_I185_R0.5060.39
174_I180_F0.5050.39
288_E521_G0.5050.39
189_V197_E0.5050.39
546_A599_I0.5050.39
254_K350_H0.5040.39
71_L224_A0.5040.39
437_D480_T0.5040.39
285_V362_L0.5030.39
302_G478_V0.5030.39
319_G370_M0.5030.39
319_G323_P0.5020.39
281_E362_L0.5000.39
298_T359_I0.5000.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1qf6A 1 0.9829 100 0.356 Contact Map
1nyrA 2 0.9953 100 0.37 Contact Map
3uh0A 2 0.6159 100 0.663 Contact Map
1evlA 2 0.6112 100 0.665 Contact Map
4hwtA 2 0.6096 100 0.666 Contact Map
3a32A 2 0.6174 100 0.674 Contact Map
3qneA 2 0.6656 100 0.722 Contact Map
1atiA 2 0.5661 100 0.726 Contact Map
2zt5A 2 0.5537 100 0.727 Contact Map
2j3lA 2 0.6252 100 0.727 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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