CARY - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

CARY - Carbamoyl-phosphate synthase arginine-specific large chain

UniProt:	P18185	Sequences: MPKDTSISSILVIGSGPIIIGQAAEFDYSGTQGCIALKEEGYRVILVNSNPATIMTDEAFADEIYFEPLTAESLTAIIKKERPDGLLANLGGQTALNLAVELEETGVLKEHGVKLLGTSVETIQKGEDREKFRSLMNELKQPVPESEIVDNEADALHFAESIGFPVIIRPAYTLGGKGGGIAPDKEAFTAMIKQALLASPINQCLVEKSIAGFKEIEYEVMRDSNNTCITVCNMENIDPVGVHTGDSIVVAPSQTLTDEDYQMLRTASLTIISALDVVGGCNIQFALDPFSKQYYVIEVNPRVSRSSALASKATGYPIAKMAAKLAVGYTLDELKNPLTGSTYASFEPALDYVIVKFPRWPFDKFKNADRKLGTKMKATGEVMAIERNLEAAIQKAAASLELKNIGTHLPELSGLSIDTLWDLAITPDDRRFFVVMELLSRSVSIDDIHEKTKIDPFFLHTFDNIIKLENRLMEAGSDLSFELLKKAKEKGFSDATIASLISKTEEEVRALRKEMGITPSFKIVDTCAAEFDAKTNYFYSTYFGETDGDISRKEKKRALIIGSGPIRIGQGVEFDYSAVHGVLTLQELGFETIMINNNPETVSTDYEIADRLYFEPMTTEHIVNVAEQENIDFAIVQFGGQTAINAAEALEKAGITLLGTSFQTLDVLEDRDQFYQLLDELGLKHAKGEIAYTKEEAASKASEIGYPVLIRPSYVIGGMGMIIVDSQAQLSQLLNDEDSMPYPILIDQYVSGKEVEIDLISDGEEVFIPTYTEHIERAGVHSGDSFAILPGPSITSGLQQGMKDAAQKIARKLSFKGIMNIQFVIDNGNILVLEVNPRASRTVPVVSKVMGVPMIPLATRLLAGASLKDLNPAVQNHHGVAVKFPVFSSHAIQDVDVKLGPEMKSTGEGMCVAYDSNSALKKIYTRVWSQKGSIYLQNVPEDVKELAENAGFTIHEGTFASWMEQEGNSLHINLSGSEEARKERLEAMTHGIPVFTEEETVRAFLQSGSGHPQPVSLKDLYKKEVASCTQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	1030 (1021)
Sequences:	2856 (1138)
Seq/√Len:	35.6

ECOLI - CARB
BACSU - CARY CARB
HALSA - CARB
SULSO - CARB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
355_V	392_A	7.069	1.00
463_D	467_K	5.400	1.00
226_N	273_S	4.832	1.00
9_S	43_R	4.624	1.00
9_S	45_I	4.595	1.00
559_L	595_I	4.325	1.00
69_L	98_L	4.293	1.00
288_D	291_S	4.250	1.00
702_S	727_Q	4.236	1.00
104_E	124_Q	4.218	1.00
680_E	812_K	4.170	1.00
82_R	111_H	4.162	1.00
860_R	865_A	4.091	1.00
663_Q	673_Q	4.060	1.00
556_K	632_D	3.904	1.00
155_A	192_I	3.657	1.00
192_I	204_C	3.600	1.00
619_T	623_V	3.563	1.00
936_L	950_A	3.555	1.00
437_E	441_R	3.516	1.00
933_S	960_A	3.497	1.00
218_Y	233_N	3.434	1.00
288_D	293_Q	3.427	1.00
398_A	621_H	3.393	1.00
913_A	918_S	3.348	1.00
10_I	42_Y	3.328	1.00
138_E	274_A	3.291	1.00
792_P	880_V	3.236	1.00
804_D	808_K	3.134	1.00
237_I	462_F	3.100	1.00
764_E	866_S	3.085	1.00
78_I	111_H	3.066	1.00
233_N	253_S	3.065	1.00
264_L	294_Y	3.053	1.00
435_V	448_I	3.027	1.00
75_T	110_E	3.021	1.00
145_E	208_K	2.978	1.00
79_K	111_H	2.972	1.00
708_V	746_I	2.971	1.00
595_I	625_V	2.969	1.00
439_L	459_L	2.960	1.00
468_L	490_K	2.885	1.00
866_S	869_D	2.876	1.00
42_Y	327_V	2.840	1.00
513_K	627_E	2.823	1.00
75_T	79_K	2.780	1.00
156_L	189_T	2.777	1.00
160_E	185_K	2.750	1.00
940_P	943_V	2.724	1.00
865_A	869_D	2.708	1.00
43_R	63_E	2.706	1.00
698_A	731_S	2.694	1.00
759_L	806_A	2.676	1.00
760_I	861_L	2.659	1.00
446_D	456_P	2.650	1.00
796_S	800_Q	2.629	1.00
75_T	111_H	2.615	1.00
4_D	114_K	2.578	1.00
970_L	974_L	2.576	1.00
546_T	628_Q	2.569	1.00
559_L	626_A	2.546	1.00
130_E	134_S	2.534	1.00
689_E	703_E	2.518	1.00
393_I	432_F	2.515	1.00
149_V	158_F	2.512	1.00
884_F	923_I	2.510	1.00
390_E	461_T	2.496	1.00
439_L	445_I	2.491	1.00
185_K	189_T	2.452	1.00
481_F	485_K	2.451	1.00
955_H	977_S	2.446	1.00
10_I	327_V	2.442	1.00
706_Y	727_Q	2.438	1.00
421_W	447_D	2.407	1.00
74_L	98_L	2.398	1.00
386_E	391_A	2.396	1.00
555_K	591_E	2.387	1.00
968_N	978_E	2.383	1.00
159_A	164_F	2.371	1.00
684_K	805_A	2.371	1.00
47_V	77_I	2.340	0.99
485_K	489_E	2.322	0.99
587_E	856_P	2.289	0.99
71_A	101_E	2.286	0.99
272_I	283_I	2.284	0.99
471_R	486_K	2.281	0.99
151_N	154_D	2.279	0.99
933_S	962_W	2.275	0.99
626_A	655_I	2.275	0.99
726_S	729_Q	2.252	0.99
799_Q	876_N	2.246	0.99
218_Y	253_S	2.245	0.99
75_T	105_T	2.235	0.99
416_S	419_T	2.230	0.99
689_E	700_K	2.223	0.99
866_S	870_L	2.208	0.99
664_T	814_S	2.192	0.99
141_Q	270_T	2.191	0.99
857_L	870_L	2.188	0.99
559_L	625_V	2.185	0.99
509_R	623_V	2.147	0.99
39_E	324_K	2.145	0.99
553_K	591_E	2.144	0.99
807_Q	811_R	2.135	0.99
504_T	507_E	2.128	0.99
443_V	447_D	2.125	0.99
242_V	427_P	2.118	0.99
208_K	293_Q	2.114	0.99
142_P	293_Q	2.104	0.99
483_L	487_A	2.104	0.99
271_I	296_V	2.090	0.99
164_F	185_K	2.086	0.99
150_D	203_Q	2.083	0.99
683_L	805_A	2.082	0.99
769_P	854_M	2.050	0.99
370_R	429_D	2.049	0.99
765_E	868_K	2.046	0.99
375_K	891_A	2.043	0.99
100_V	120_V	2.040	0.99
801_G	804_D	2.038	0.99
947_A	970_L	2.018	0.98
394_Q	492_F	2.017	0.98
475_A	480_S	2.008	0.98
439_L	448_I	2.007	0.98
164_F	184_D	2.003	0.98
506_E	652_K	1.993	0.98
71_A	105_T	1.987	0.98
390_E	464_N	1.981	0.98
960_A	979_E	1.980	0.98
755_V	794_I	1.977	0.98
141_Q	267_A	1.976	0.98
417_I	441_R	1.965	0.98
147_E	161_S	1.962	0.98
737_E	744_I	1.958	0.98
651_E	663_Q	1.947	0.98
698_A	727_Q	1.938	0.98
76_A	79_K	1.936	0.98
171_A	203_Q	1.930	0.98
666_D	714_Y	1.907	0.98
666_D	673_Q	1.899	0.98
613_Y	629_E	1.898	0.98
727_Q	731_S	1.897	0.98
79_K	110_E	1.897	0.98
513_K	518_T	1.888	0.98
287_L	294_Y	1.882	0.98
75_T	107_V	1.880	0.97
78_I	113_V	1.877	0.97
40_E	324_K	1.876	0.97
182_A	191_M	1.876	0.97
159_A	166_V	1.872	0.97
66_F	910_M	1.854	0.97
445_I	459_L	1.851	0.97
587_E	860_R	1.837	0.97
797_G	828_G	1.833	0.97
693_T	696_E	1.827	0.97
47_V	74_L	1.827	0.97
435_V	454_I	1.822	0.97
757_I	806_A	1.818	0.97
253_S	261_Y	1.816	0.97
511_L	515_M	1.814	0.97
699_S	703_E	1.811	0.97
687_K	703_E	1.810	0.97
648_E	652_K	1.803	0.97
103_E	120_V	1.799	0.97
968_N	980_A	1.798	0.97
929_S	932_G	1.783	0.97
184_D	187_A	1.781	0.97
981_R	995_F	1.781	0.97
588_L	860_R	1.778	0.96
947_A	974_L	1.771	0.96
691_A	700_K	1.771	0.96
150_D	154_D	1.766	0.96
494_D	512_R	1.752	0.96
470_N	473_M	1.747	0.96
942_D	1007_S	1.746	0.96
9_S	63_E	1.740	0.96
558_A	658_L	1.734	0.96
147_E	158_F	1.728	0.96
755_V	825_I	1.721	0.96
684_K	829_N	1.718	0.96
732_Q	736_D	1.709	0.96
1004_F	1024_E	1.702	0.95
755_V	802_M	1.698	0.95
738_D	744_I	1.696	0.95
151_N	202_N	1.693	0.95
436_M	440_S	1.692	0.95
135_L	274_A	1.684	0.95
720_G	737_E	1.682	0.95
518_T	627_E	1.679	0.95
761_S	811_R	1.675	0.95
439_L	462_F	1.673	0.95
168_I	204_C	1.671	0.95
677_L	809_I	1.666	0.95
436_M	462_F	1.666	0.95
795_T	828_G	1.663	0.95
444_S	447_D	1.658	0.95
168_I	206_V	1.647	0.95
801_G	805_A	1.644	0.95
449_H	459_L	1.642	0.94
424_A	438_L	1.638	0.94
124_Q	131_K	1.633	0.94
183_P	187_A	1.625	0.94
795_T	798_L	1.612	0.94
510_A	514_E	1.611	0.94
196_L	202_N	1.609	0.94
990_H	994_V	1.609	0.94
275_L	299_V	1.606	0.94
533_A	536_N	1.601	0.94
388_N	543_F	1.593	0.94
260_D	292_K	1.589	0.93
588_L	863_A	1.583	0.93
619_T	649_A	1.581	0.93
164_F	188_F	1.578	0.93
687_K	748_Q	1.572	0.93
962_W	1001_V	1.571	0.93
125_K	274_A	1.561	0.93
759_L	819_M	1.557	0.93
465_I	492_F	1.552	0.93
677_L	812_K	1.549	0.93
382_V	399_S	1.548	0.93
963_M	978_E	1.547	0.92
133_R	137_N	1.546	0.92
103_E	109_K	1.544	0.92
71_A	74_L	1.539	0.92
389_L	457_F	1.538	0.92
73_S	77_I	1.536	0.92
168_I	188_F	1.535	0.92
1022_K	1026_A	1.531	0.92
585_L	863_A	1.530	0.92
798_L	828_G	1.529	0.92
755_V	830_I	1.528	0.92
684_K	801_G	1.527	0.92
218_Y	268_S	1.524	0.92
585_L	592_T	1.523	0.92
224_S	330_T	1.520	0.92
397_A	432_F	1.517	0.92
71_A	98_L	1.516	0.92
480_S	483_L	1.501	0.91
556_K	590_F	1.500	0.91
464_N	490_K	1.496	0.91
915_D	918_S	1.496	0.91
675_Y	685_H	1.494	0.91
798_L	830_I	1.492	0.91
791_G	799_Q	1.490	0.91
149_V	154_D	1.487	0.91
825_I	830_I	1.485	0.91
86_L	113_V	1.480	0.91
523_I	538_F	1.479	0.91
801_G	830_I	1.476	0.91
508_V	511_L	1.472	0.90
107_V	111_H	1.468	0.90
511_L	514_E	1.467	0.90
405_I	499_S	1.465	0.90
443_V	448_I	1.464	0.90
983_E	1016_S	1.464	0.90
619_T	653_A	1.460	0.90
393_I	407_T	1.458	0.90
484_L	511_L	1.452	0.90
786_F	884_F	1.450	0.90
760_I	854_M	1.444	0.90
635_I	859_T	1.444	0.90
505_E	509_R	1.439	0.89
497_I	501_I	1.439	0.89
88_A	99_A	1.437	0.89
144_P	295_Y	1.431	0.89
798_L	825_I	1.430	0.89
468_L	487_A	1.430	0.89
805_A	830_I	1.425	0.89
859_T	863_A	1.424	0.89
800_Q	803_K	1.424	0.89
767_F	872_P	1.422	0.89
632_D	656_T	1.422	0.89
673_Q	714_Y	1.401	0.88
421_W	443_V	1.399	0.88
664_T	667_V	1.395	0.88
865_A	870_L	1.393	0.88
938_N	946_L	1.391	0.88
149_V	155_A	1.390	0.88
558_A	863_A	1.383	0.87
678_L	832_V	1.374	0.87
225_N	330_T	1.374	0.87
421_W	451_K	1.372	0.87
449_H	453_K	1.365	0.87
321_M	337_P	1.362	0.87
592_T	863_A	1.361	0.87
513_K	624_N	1.359	0.87
152_E	188_F	1.357	0.86
683_L	830_I	1.355	0.86
237_I	248_I	1.354	0.86
420_L	448_I	1.352	0.86
472_L	487_A	1.352	0.86
69_L	74_L	1.350	0.86
750_V	826_D	1.347	0.86
928_W	932_G	1.346	0.86
134_S	138_E	1.345	0.86
101_E	104_E	1.342	0.86
806_A	823_F	1.341	0.86
495_A	505_E	1.335	0.86
667_V	812_K	1.334	0.85
950_A	961_S	1.326	0.85
159_A	188_F	1.323	0.85
468_L	483_L	1.322	0.85
634_A	655_I	1.318	0.85
701_A	706_Y	1.314	0.85
553_K	557_R	1.313	0.85
439_L	463_D	1.306	0.84
1018_K	1022_K	1.305	0.84
1008_G	1014_P	1.304	0.84
558_A	585_L	1.295	0.84
761_S	766_V	1.293	0.84
557_R	591_E	1.291	0.84
472_L	500_L	1.289	0.83
465_I	490_K	1.282	0.83
481_F	515_M	1.281	0.83
417_I	447_D	1.279	0.83
6_S	114_K	1.278	0.83
221_M	321_M	1.277	0.83
70_T	73_S	1.277	0.83
801_G	829_N	1.276	0.83
263_M	287_L	1.275	0.83
237_I	435_V	1.274	0.83
969_S	973_N	1.267	0.82
518_T	624_N	1.267	0.82
257_T	260_D	1.266	0.82
972_I	978_E	1.263	0.82
40_E	329_Y	1.254	0.82
341_S	534_K	1.253	0.82
394_Q	406_G	1.253	0.82
972_I	980_A	1.253	0.82
982_K	991_G	1.253	0.82
152_E	156_L	1.250	0.81
809_I	821_I	1.249	0.81
461_T	464_N	1.249	0.81
237_I	250_V	1.248	0.81
126_G	283_I	1.245	0.81
394_Q	465_I	1.242	0.81
146_S	207_E	1.241	0.81
11_L	86_L	1.232	0.81
100_V	131_K	1.231	0.80
475_A	483_L	1.226	0.80
440_S	469_E	1.224	0.80
393_I	462_F	1.223	0.80
479_L	484_L	1.220	0.80
404_N	433_F	1.215	0.80
623_V	655_I	1.209	0.79
635_I	862_L	1.207	0.79
734_L	737_E	1.198	0.79
457_F	461_T	1.198	0.79
675_Y	688_G	1.197	0.79
329_Y	334_L	1.196	0.78
734_L	738_D	1.189	0.78
443_V	451_K	1.186	0.78
472_L	497_I	1.186	0.78
676_Q	680_E	1.184	0.78
194_Q	198_A	1.183	0.78
157_H	160_E	1.178	0.77
503_K	508_V	1.178	0.77
788_I	916_S	1.177	0.77
479_L	501_I	1.171	0.77
965_Q	980_A	1.164	0.77
503_K	507_E	1.162	0.76
799_Q	803_K	1.157	0.76
1008_G	1017_L	1.157	0.76
583_L	608_I	1.151	0.76
550_I	628_Q	1.150	0.76
125_K	135_L	1.149	0.76
549_D	552_R	1.149	0.76
936_L	971_H	1.144	0.75
170_P	179_G	1.140	0.75
71_A	107_V	1.140	0.75
771_Y	803_K	1.139	0.75
86_L	108_L	1.137	0.75
126_G	720_G	1.137	0.75
588_L	865_A	1.136	0.75
184_D	989_T	1.135	0.75
424_A	452_T	1.135	0.75
155_A	206_V	1.134	0.75
519_P	542_Y	1.129	0.74
611_R	629_E	1.127	0.74
47_V	102_L	1.126	0.74
405_I	495_A	1.125	0.74
71_A	75_T	1.124	0.74
34_C	60_F	1.121	0.74
766_V	811_R	1.115	0.73
131_K	134_S	1.114	0.73
267_A	294_Y	1.114	0.73
720_G	738_D	1.113	0.73
436_M	466_I	1.113	0.73
561_I	622_I	1.110	0.73
250_V	355_V	1.108	0.73
125_K	138_E	1.108	0.73
124_Q	172_Y	1.106	0.73
805_A	823_F	1.106	0.73
208_K	295_Y	1.105	0.73
99_A	115_L	1.104	0.73
448_I	462_F	1.104	0.73
390_E	490_K	1.103	0.73
423_L	434_V	1.100	0.72
449_H	456_P	1.100	0.72
13_I	74_L	1.100	0.72
417_I	421_W	1.097	0.72
133_R	207_E	1.092	0.72
861_L	870_L	1.091	0.72
471_R	483_L	1.088	0.72
621_H	624_N	1.084	0.71
13_I	95_A	1.083	0.71
632_D	658_L	1.083	0.71
221_M	272_I	1.080	0.71
522_K	545_E	1.079	0.71
724_V	744_I	1.078	0.71
845_V	910_M	1.077	0.71
337_P	606_Y	1.074	0.71
227_T	345_S	1.072	0.70
100_V	124_Q	1.072	0.70
423_L	428_D	1.072	0.70
952_F	956_E	1.069	0.70
218_Y	228_C	1.067	0.70
471_R	475_A	1.065	0.70
388_N	490_K	1.065	0.70
321_M	334_L	1.065	0.70
188_F	206_V	1.065	0.70
989_T	994_V	1.065	0.70
938_N	950_A	1.057	0.69
984_R	993_P	1.056	0.69
437_E	440_S	1.052	0.69
141_Q	296_V	1.052	0.69
509_R	653_A	1.051	0.69
155_A	168_I	1.047	0.69
683_L	801_G	1.047	0.69
137_N	143_V	1.046	0.68
552_R	611_R	1.046	0.68
340_G	534_K	1.045	0.68
142_P	208_K	1.044	0.68
771_Y	799_Q	1.044	0.68
258_D	262_Q	1.043	0.68
262_Q	265_R	1.040	0.68
484_L	517_I	1.039	0.68
228_C	269_L	1.038	0.68
191_M	195_A	1.037	0.68
809_I	832_V	1.035	0.68
13_I	69_L	1.034	0.68
382_V	396_A	1.031	0.67
228_C	273_S	1.030	0.67
259_E	292_K	1.029	0.67
806_A	821_I	1.028	0.67
582_V	609_A	1.028	0.67
250_V	389_L	1.027	0.67
934_I	1005_L	1.026	0.67
623_V	653_A	1.024	0.67
227_T	330_T	1.022	0.67
121_E	131_K	1.022	0.67
19_I	177_K	1.022	0.67
438_L	443_V	1.021	0.67
498_A	504_T	1.018	0.66
36_A	334_L	1.017	0.66
336_N	339_T	1.017	0.66
214_K	455_D	1.016	0.66
207_E	210_I	1.016	0.66
624_N	627_E	1.015	0.66
983_E	1020_L	1.015	0.66
141_Q	283_I	1.015	0.66
192_I	206_V	1.014	0.66
388_N	392_A	1.011	0.66
168_I	192_I	1.010	0.66
420_L	441_R	1.009	0.66
996_T	1020_L	1.005	0.65
278_V	325_L	1.000	0.65
266_T	270_T	1.000	0.65
38_K	60_F	1.000	0.65
159_A	192_I	0.999	0.65
789_L	846_V	0.998	0.65
937_Q	967_G	0.993	0.64
617_M	646_A	0.990	0.64
448_I	459_L	0.990	0.64
962_W	979_E	0.988	0.64
982_K	990_H	0.987	0.64
101_E	105_T	0.986	0.64
35_I	607_E	0.982	0.64
731_S	735_N	0.981	0.63
860_R	870_L	0.981	0.63
228_C	272_I	0.981	0.63
357_F	360_W	0.979	0.63
290_F	453_K	0.977	0.63
582_V	592_T	0.976	0.63
697_A	734_L	0.974	0.63
424_A	434_V	0.974	0.63
786_F	885_P	0.973	0.63
811_R	814_S	0.972	0.63
714_Y	742_Y	0.971	0.63
996_T	1023_K	0.971	0.63
121_E	125_K	0.970	0.63
849_V	881_A	0.968	0.62
1_M	7_I	0.963	0.62
961_S	978_E	0.962	0.62
85_G	88_A	0.961	0.62
933_S	979_E	0.961	0.62
387_R	522_K	0.960	0.62
692_Y	696_E	0.960	0.62
225_N	332_D	0.959	0.62
262_Q	530_E	0.956	0.61
271_I	631_I	0.955	0.61
234_M	249_V	0.953	0.61
881_A	912_V	0.951	0.61
816_K	861_L	0.950	0.61
935_Y	964_E	0.950	0.61
189_T	193_K	0.943	0.60
184_D	998_E	0.943	0.60
218_Y	261_Y	0.942	0.60
404_N	410_P	0.941	0.60
262_Q	531_F	0.940	0.60
107_V	110_E	0.939	0.60
408_H	499_S	0.939	0.60
164_F	189_T	0.938	0.60
145_E	293_Q	0.938	0.60
982_K	988_M	0.937	0.60
579_V	1018_K	0.935	0.60
932_G	959_F	0.935	0.60
221_M	229_I	0.934	0.60
353_V	392_A	0.934	0.60
791_G	794_I	0.933	0.59
522_K	543_F	0.930	0.59
253_S	350_L	0.928	0.59
460_H	463_D	0.927	0.59
445_I	463_D	0.925	0.59
133_R	148_I	0.923	0.59
468_L	471_R	0.922	0.59
220_V	230_T	0.922	0.59
1016_S	1020_L	0.920	0.58
417_I	443_V	0.917	0.58
213_F	295_Y	0.912	0.58
462_F	466_I	0.912	0.58
24_A	566_I	0.911	0.58
694_K	731_S	0.910	0.58
757_I	802_M	0.909	0.57
320_K	337_P	0.909	0.57
394_Q	457_F	0.908	0.57
4_D	42_Y	0.908	0.57
519_P	624_N	0.907	0.57
591_E	611_R	0.906	0.57
180_G	191_M	0.906	0.57
45_I	77_I	0.905	0.57
773_E	793_S	0.903	0.57
144_P	210_I	0.903	0.57
581_G	635_I	0.902	0.57
638_F	858_A	0.902	0.57
8_S	43_R	0.900	0.57
481_F	517_I	0.898	0.57
936_L	961_S	0.898	0.57
268_S	285_F	0.895	0.56
933_S	995_F	0.894	0.56
156_L	168_I	0.894	0.56
468_L	486_K	0.894	0.56
964_E	967_G	0.893	0.56
752_G	824_V	0.892	0.56
734_L	744_I	0.891	0.56
766_V	807_Q	0.890	0.56
498_A	508_V	0.889	0.56
379_T	566_I	0.889	0.56
738_D	742_Y	0.888	0.56
258_D	531_F	0.886	0.56
559_L	632_D	0.885	0.55
879_G	912_V	0.884	0.55
210_I	240_V	0.882	0.55
387_R	543_F	0.882	0.55
962_W	995_F	0.881	0.55
74_L	77_I	0.880	0.55
517_I	542_Y	0.879	0.55
265_R	347_E	0.878	0.55
445_I	460_H	0.878	0.55
167_I	181_I	0.876	0.55
128_D	203_Q	0.876	0.55
678_L	682_G	0.874	0.54
156_L	164_F	0.872	0.54
166_V	206_V	0.871	0.54
936_L	1005_L	0.870	0.54
262_Q	346_F	0.869	0.54
987_A	994_V	0.868	0.54
11_L	78_I	0.868	0.54
944_K	948_E	0.867	0.54
156_L	185_K	0.866	0.54
402_L	433_F	0.865	0.54
164_F	631_I	0.864	0.54
946_L	971_H	0.864	0.54
354_I	385_I	0.862	0.53
484_L	508_V	0.860	0.53
267_A	271_I	0.860	0.53
447_D	450_E	0.859	0.53
154_D	157_H	0.859	0.53
248_I	432_F	0.858	0.53
342_T	346_F	0.857	0.53
803_K	874_V	0.854	0.53
412_L	434_V	0.854	0.53
802_M	806_A	0.854	0.53
286_A	295_Y	0.853	0.53
590_F	632_D	0.853	0.53
246_D	372_L	0.853	0.53
767_F	852_V	0.851	0.53
449_H	454_I	0.851	0.53
685_H	720_G	0.851	0.53
234_M	299_V	0.850	0.52
379_T	597_N	0.849	0.52
156_L	159_A	0.849	0.52
943_V	983_E	0.847	0.52
799_Q	806_A	0.847	0.52
47_V	69_L	0.846	0.52
218_Y	254_Q	0.846	0.52
391_A	491_G	0.845	0.52
686_A	716_I	0.845	0.52
2_P	333_E	0.844	0.52
383_M	614_F	0.844	0.52
346_F	530_E	0.843	0.52
336_N	525_D	0.843	0.52
346_F	535_T	0.842	0.52
265_R	346_F	0.841	0.52
145_E	161_S	0.841	0.52
281_C	299_V	0.840	0.52
357_F	396_A	0.840	0.52
450_E	453_K	0.839	0.51
826_D	829_N	0.836	0.51
464_N	468_L	0.836	0.51
394_Q	496_T	0.835	0.51
961_S	976_G	0.835	0.51
650_L	655_I	0.835	0.51
213_F	607_E	0.835	0.51
177_K	891_A	0.834	0.51
507_E	510_A	0.833	0.51
786_F	924_Y	0.833	0.51
716_I	845_V	0.833	0.51
408_H	436_M	0.831	0.51
321_M	340_G	0.830	0.51
579_V	583_L	0.830	0.51
226_N	230_T	0.829	0.51
963_M	967_G	0.829	0.51
242_V	426_T	0.828	0.51
761_S	819_M	0.827	0.50
201_I	533_A	0.826	0.50
102_L	108_L	0.825	0.50
1006_Q	1020_L	0.824	0.50
371_K	426_T	0.824	0.50
739_S	744_I	0.821	0.50
168_I	195_A	0.820	0.50
558_A	590_F	0.819	0.50
166_V	188_F	0.818	0.50
152_E	155_A	0.818	0.50
149_V	204_C	0.816	0.49
341_S	533_A	0.815	0.49
936_L	946_L	0.814	0.49
808_K	812_K	0.813	0.49
420_L	438_L	0.813	0.49
943_V	966_E	0.813	0.49
234_M	294_Y	0.812	0.49
5_T	42_Y	0.810	0.49
566_I	597_N	0.810	0.49
207_E	617_M	0.810	0.49
592_T	859_T	0.810	0.49
153_A	157_H	0.809	0.49
166_V	192_I	0.809	0.49
619_T	646_A	0.809	0.49
775_I	788_I	0.808	0.49
484_L	512_R	0.808	0.49
802_M	825_I	0.808	0.49
168_I	191_M	0.808	0.49
520_S	543_F	0.806	0.49
802_M	830_I	0.806	0.49
230_T	338_L	0.806	0.49
577_S	855_I	0.806	0.49
94_T	174_L	0.805	0.49
850_M	872_P	0.805	0.49
756_E	769_P	0.804	0.48
1009_S	1017_L	0.803	0.48
420_L	434_V	0.803	0.48
234_M	379_T	0.802	0.48
133_R	205_L	0.802	0.48
262_Q	527_C	0.801	0.48
149_V	833_L	0.801	0.48
157_H	161_S	0.800	0.48
724_V	737_E	0.799	0.48
141_Q	294_Y	0.799	0.48
728_A	731_S	0.798	0.48
152_E	159_A	0.798	0.48
496_T	500_L	0.797	0.48
992_I	1020_L	0.796	0.48
968_N	972_I	0.795	0.48
760_I	872_P	0.794	0.48
877_H	881_A	0.794	0.48
357_F	432_F	0.793	0.48
206_V	264_L	0.793	0.48
677_L	813_L	0.793	0.48
583_L	587_E	0.792	0.47
672_D	692_Y	0.791	0.47
399_S	616_P	0.790	0.47
152_E	192_I	0.789	0.47
218_Y	272_I	0.788	0.47
733_L	738_D	0.787	0.47
815_F	819_M	0.787	0.47
31_T	55_M	0.786	0.47
19_I	242_V	0.786	0.47
987_A	991_G	0.786	0.47
439_L	443_V	0.786	0.47
369_D	429_D	0.785	0.47
345_S	581_G	0.784	0.47
85_G	116_L	0.784	0.47
506_E	653_A	0.784	0.47
833_L	1011_H	0.783	0.47
675_Y	709_L	0.780	0.46
775_I	833_L	0.780	0.46
695_E	699_S	0.779	0.46
546_T	550_I	0.777	0.46
183_P	211_A	0.777	0.46
58_E	851_G	0.776	0.46
672_D	690_I	0.776	0.46
346_F	531_F	0.775	0.46
336_N	535_T	0.775	0.46
177_K	375_K	0.775	0.46
479_L	508_V	0.775	0.46
648_E	651_E	0.774	0.46
386_E	491_G	0.774	0.46
57_D	576_Y	0.772	0.46
339_T	525_D	0.772	0.46
233_N	261_Y	0.771	0.46
767_F	857_L	0.771	0.46
939_V	1017_L	0.771	0.46
726_S	746_I	0.770	0.46
699_S	702_S	0.770	0.46
933_S	1002_R	0.768	0.45
4_D	10_I	0.768	0.45
265_R	525_D	0.767	0.45
971_H	978_E	0.766	0.45
706_Y	936_L	0.766	0.45
934_I	950_A	0.765	0.45
347_E	525_D	0.765	0.45
719_M	738_D	0.764	0.45
119_S	224_S	0.764	0.45
221_M	323_A	0.763	0.45
737_E	740_M	0.763	0.45
86_L	976_G	0.762	0.45
553_K	611_R	0.761	0.45
710_I	806_A	0.760	0.45
47_V	107_V	0.760	0.45
884_F	924_Y	0.760	0.45
985_L	991_G	0.759	0.45
987_A	990_H	0.757	0.44
249_V	294_Y	0.757	0.44
695_E	731_S	0.757	0.44
79_K	82_R	0.756	0.44
478_D	501_I	0.755	0.44
360_W	402_L	0.755	0.44
12_V	44_V	0.753	0.44
767_F	873_A	0.752	0.44
337_P	607_E	0.752	0.44
983_E	988_M	0.751	0.44
90_L	210_I	0.751	0.44
509_R	624_N	0.750	0.44
937_Q	964_E	0.750	0.44
622_I	646_A	0.750	0.44
667_V	677_L	0.749	0.44
755_V	887_F	0.749	0.44
60_F	64_I	0.749	0.44
155_A	205_L	0.748	0.44
249_V	299_V	0.748	0.44
5_T	10_I	0.747	0.44
960_A	977_S	0.747	0.44
966_E	983_E	0.746	0.43
166_V	182_A	0.746	0.43
258_D	265_R	0.746	0.43
885_P	923_I	0.746	0.43
152_E	181_I	0.746	0.43
825_I	828_G	0.745	0.43
162_I	167_I	0.745	0.43
527_C	531_F	0.745	0.43
391_A	541_T	0.745	0.43
229_I	597_N	0.744	0.43
10_I	855_I	0.743	0.43
488_K	620_E	0.742	0.43
691_A	739_S	0.742	0.43
177_K	913_A	0.742	0.43
130_E	148_I	0.742	0.43
581_G	859_T	0.741	0.43
104_E	518_T	0.740	0.43
984_R	1016_S	0.740	0.43
501_I	508_V	0.739	0.43
361_P	379_T	0.738	0.43
496_T	499_S	0.736	0.43
750_V	825_I	0.736	0.43
1004_F	1020_L	0.735	0.43
389_L	461_T	0.735	0.43
346_F	525_D	0.734	0.42
188_F	200_P	0.734	0.42
55_M	246_D	0.734	0.42
242_V	371_K	0.732	0.42
31_T	60_F	0.732	0.42
339_T	347_E	0.731	0.42
561_I	617_M	0.730	0.42
847_S	854_M	0.730	0.42
753_K	798_L	0.728	0.42
885_P	888_S	0.728	0.42
692_Y	738_D	0.728	0.42
124_Q	399_S	0.727	0.42
218_Y	229_I	0.726	0.42
271_I	283_I	0.725	0.42
250_V	815_F	0.725	0.42
141_Q	299_V	0.725	0.42
684_K	830_I	0.724	0.42
424_A	451_K	0.724	0.42
221_M	231_V	0.723	0.42
584_T	856_P	0.722	0.41
148_I	171_A	0.722	0.41
339_T	535_T	0.722	0.41
484_L	515_M	0.722	0.41
233_N	254_Q	0.721	0.41
261_Y	346_F	0.721	0.41
750_V	810_A	0.720	0.41
336_N	347_E	0.718	0.41
756_E	888_S	0.718	0.41
697_A	737_E	0.717	0.41
234_M	566_I	0.717	0.41
532_D	536_N	0.717	0.41
993_P	1020_L	0.716	0.41
561_I	636_V	0.716	0.41
29_S	95_A	0.716	0.41
909_G	926_R	0.716	0.41
819_M	835_V	0.716	0.41
172_Y	809_I	0.715	0.41
979_E	1000_T	0.715	0.41
809_I	819_M	0.715	0.41
767_F	850_M	0.714	0.41
160_E	164_F	0.714	0.41
764_E	811_R	0.714	0.41
258_D	339_T	0.713	0.41
288_D	295_Y	0.713	0.41
231_V	253_S	0.713	0.41
180_G	195_A	0.712	0.41
678_L	740_M	0.712	0.41
421_W	448_I	0.710	0.40
516_G	869_D	0.708	0.40
778_A	824_V	0.707	0.40
964_E	1020_L	0.707	0.40
162_I	959_F	0.707	0.40
508_V	516_G	0.706	0.40
972_I	977_S	0.706	0.40
549_D	553_K	0.706	0.40
654_G	763_G	0.706	0.40
498_A	503_K	0.705	0.40
446_D	450_E	0.704	0.40
934_I	954_I	0.704	0.40
277_V	561_I	0.703	0.40
152_E	168_I	0.702	0.40
720_G	739_S	0.701	0.40
164_F	168_I	0.700	0.40
86_L	107_V	0.699	0.40
773_E	792_P	0.699	0.40
299_V	379_T	0.699	0.40
335_K	343_Y	0.698	0.39
494_D	509_R	0.696	0.39
636_V	657_L	0.696	0.39
258_D	336_N	0.696	0.39
559_L	655_I	0.696	0.39
283_I	403_K	0.696	0.39
170_P	173_T	0.694	0.39
153_A	474_E	0.694	0.39
78_I	107_V	0.694	0.39
753_K	793_S	0.694	0.39
231_V	589_G	0.694	0.39
799_Q	830_I	0.693	0.39
824_V	888_S	0.693	0.39
993_P	1023_K	0.692	0.39
207_E	823_F	0.691	0.39
560_I	592_T	0.690	0.39
818_I	855_I	0.689	0.39
1022_K	1025_V	0.689	0.39
234_M	325_L	0.687	0.39
404_N	408_H	0.686	0.38
995_F	1000_T	0.685	0.38
702_S	706_Y	0.685	0.38
797_G	801_G	0.685	0.38
439_L	465_I	0.684	0.38
694_K	735_N	0.683	0.38
258_D	347_E	0.682	0.38
719_M	737_E	0.682	0.38
424_A	923_I	0.681	0.38
77_I	325_L	0.680	0.38
930_Q	959_F	0.679	0.38
697_A	701_A	0.678	0.38
679_D	685_H	0.677	0.38
700_K	746_I	0.676	0.38
694_K	734_L	0.675	0.38
24_A	379_T	0.675	0.38
213_F	293_Q	0.674	0.37
367_N	904_K	0.674	0.37
566_I	892_I	0.673	0.37
385_I	524_V	0.671	0.37
700_K	737_E	0.668	0.37
361_P	904_K	0.668	0.37
7_I	11_L	0.667	0.37
316_Y	892_I	0.666	0.37
407_T	466_I	0.666	0.37
66_F	572_V	0.665	0.37
135_L	138_E	0.665	0.37
521_F	540_S	0.665	0.37
661_S	664_T	0.665	0.37
865_A	868_K	0.664	0.37
184_D	997_E	0.664	0.37
173_T	179_G	0.663	0.37
249_V	379_T	0.663	0.37
530_E	535_T	0.662	0.37
249_V	281_C	0.661	0.36
861_L	866_S	0.659	0.36
234_M	275_L	0.659	0.36
44_V	981_R	0.658	0.36
177_K	198_A	0.658	0.36
538_F	597_N	0.658	0.36
805_A	808_K	0.657	0.36
167_I	182_A	0.657	0.36
249_V	566_I	0.656	0.36
261_Y	455_D	0.656	0.36
131_K	264_L	0.655	0.36
724_V	730_L	0.655	0.36
964_E	1016_S	0.655	0.36
1017_L	1021_Y	0.655	0.36
576_Y	580_H	0.655	0.36
42_Y	85_G	0.655	0.36
522_K	541_T	0.655	0.36
447_D	529_A	0.655	0.36
265_R	530_E	0.655	0.36
268_S	335_K	0.654	0.36
417_I	437_E	0.653	0.36
636_V	654_G	0.653	0.36
265_R	339_T	0.653	0.36
938_N	942_D	0.652	0.36
558_A	633_F	0.652	0.36
852_V	857_L	0.652	0.36
415_L	419_T	0.651	0.36
131_K	172_Y	0.651	0.36
690_I	734_L	0.651	0.36
218_Y	249_V	0.651	0.36
95_A	516_G	0.651	0.36
82_R	107_V	0.651	0.36
593_I	613_Y	0.650	0.36
764_E	869_D	0.650	0.36
661_S	814_S	0.650	0.36
560_I	912_V	0.649	0.35
401_E	565_P	0.649	0.35
498_A	505_E	0.649	0.35
646_A	771_Y	0.649	0.35
171_A	749_Y	0.649	0.35
34_C	38_K	0.648	0.35
323_A	618_T	0.648	0.35
12_V	34_C	0.648	0.35
557_R	593_I	0.648	0.35
944_K	970_L	0.647	0.35
997_E	1001_V	0.646	0.35
265_R	336_N	0.646	0.35
637_Q	833_L	0.646	0.35
203_Q	283_I	0.646	0.35
133_R	146_S	0.646	0.35
488_K	542_Y	0.646	0.35
651_E	662_F	0.645	0.35
448_I	452_T	0.645	0.35
159_A	168_I	0.645	0.35
560_I	585_L	0.643	0.35
6_S	42_Y	0.642	0.35
12_V	981_R	0.642	0.35
119_S	276_D	0.642	0.35
963_M	971_H	0.641	0.35
625_V	628_Q	0.641	0.35
578_A	855_I	0.641	0.35
803_K	807_Q	0.641	0.35
7_I	611_R	0.641	0.35
249_V	892_I	0.640	0.35
471_R	915_D	0.639	0.35
401_E	567_R	0.639	0.35
595_I	626_A	0.639	0.35
710_I	730_L	0.639	0.35
730_L	737_E	0.638	0.35
508_V	515_M	0.638	0.35
85_G	386_E	0.638	0.35
806_A	819_M	0.638	0.35
407_T	887_F	0.638	0.35
349_A	528_A	0.637	0.35
971_H	976_G	0.637	0.35
131_K	135_L	0.637	0.35
672_D	676_Q	0.636	0.34
239_P	453_K	0.635	0.34
937_Q	966_E	0.635	0.34
497_I	508_V	0.635	0.34
118_T	249_V	0.635	0.34
970_L	973_N	0.634	0.34
73_S	925_T	0.634	0.34
789_L	920_L	0.634	0.34
139_L	746_I	0.633	0.34
554_E	557_R	0.633	0.34
582_V	687_K	0.633	0.34
770_T	846_V	0.633	0.34
944_K	974_L	0.633	0.34
983_E	994_V	0.632	0.34
261_Y	529_A	0.632	0.34
173_T	195_A	0.631	0.34
593_I	611_R	0.631	0.34
833_L	1018_K	0.631	0.34
509_R	627_E	0.630	0.34
969_S	972_I	0.630	0.34
559_L	592_T	0.629	0.34
8_S	463_D	0.629	0.34
149_V	206_V	0.629	0.34
134_S	137_N	0.628	0.34
290_F	456_P	0.628	0.34
230_T	273_S	0.627	0.34
192_I	196_L	0.627	0.34
153_A	186_E	0.627	0.34
767_F	874_V	0.626	0.34
703_E	808_K	0.626	0.34
378_A	752_G	0.625	0.34
482_E	485_K	0.625	0.34
765_E	807_Q	0.624	0.34
213_F	337_P	0.624	0.34
447_D	451_K	0.624	0.34
512_R	542_Y	0.624	0.34
810_A	819_M	0.624	0.34
78_I	102_L	0.623	0.33
278_V	322_A	0.622	0.33
565_P	597_N	0.622	0.33
194_Q	710_I	0.621	0.33
676_Q	682_G	0.621	0.33
186_E	471_R	0.620	0.33
242_V	432_F	0.620	0.33
256_L	322_A	0.620	0.33
965_Q	969_S	0.620	0.33
422_D	426_T	0.620	0.33
171_A	180_G	0.619	0.33
645_N	719_M	0.619	0.33
118_T	278_V	0.618	0.33
439_L	464_N	0.618	0.33
699_S	728_A	0.618	0.33
201_I	323_A	0.618	0.33
213_F	577_S	0.618	0.33
78_I	110_E	0.617	0.33
347_E	530_E	0.617	0.33
8_S	84_D	0.617	0.33
408_H	496_T	0.616	0.33
144_P	667_V	0.616	0.33
734_L	739_S	0.615	0.33
47_V	80_K	0.615	0.33
229_I	321_M	0.614	0.33
541_T	771_Y	0.614	0.33
804_D	807_Q	0.614	0.33
764_E	868_K	0.614	0.33
855_I	859_T	0.614	0.33
756_E	823_F	0.614	0.33
725_D	941_E	0.613	0.33
720_G	1008_G	0.613	0.33
322_A	384_A	0.613	0.33
744_I	926_R	0.613	0.33
339_T	342_T	0.613	0.33
237_I	389_L	0.612	0.33
353_V	388_N	0.612	0.33
152_E	193_K	0.611	0.33
997_E	1023_K	0.610	0.32
487_A	517_I	0.610	0.32
24_A	249_V	0.609	0.32
757_I	830_I	0.609	0.32
49_S	66_F	0.609	0.32
780_V	972_I	0.609	0.32
398_A	493_S	0.608	0.32
809_I	813_L	0.607	0.32
149_V	192_I	0.606	0.32
67_E	78_I	0.605	0.32
94_T	386_E	0.604	0.32
991_G	1008_G	0.604	0.32
336_N	530_E	0.604	0.32
509_R	513_K	0.604	0.32
740_M	823_F	0.604	0.32
294_Y	892_I	0.603	0.32
86_L	99_A	0.603	0.32
700_K	703_E	0.603	0.32
349_A	529_A	0.602	0.32
667_V	680_E	0.601	0.32
15_S	69_L	0.601	0.32
558_A	859_T	0.601	0.32
415_L	423_L	0.601	0.32
261_Y	265_R	0.600	0.32
237_I	432_F	0.600	0.32
227_T	265_R	0.600	0.32
1005_L	1020_L	0.599	0.32
112_G	160_E	0.599	0.32
940_P	1004_F	0.598	0.32
991_G	994_V	0.598	0.32
525_D	529_A	0.598	0.32
955_H	976_G	0.598	0.32
183_P	989_T	0.597	0.31
8_S	473_M	0.597	0.31
67_E	922_K	0.597	0.31
428_D	434_V	0.597	0.31
446_D	460_H	0.596	0.31
249_V	278_V	0.596	0.31
143_V	272_I	0.596	0.31
361_P	566_I	0.596	0.31
1010_G	1013_Q	0.595	0.31
226_N	387_R	0.595	0.31
755_V	771_Y	0.595	0.31
445_I	449_H	0.594	0.31
697_A	746_I	0.594	0.31
802_M	863_A	0.594	0.31
379_T	643_A	0.594	0.31
221_M	303_V	0.594	0.31
47_V	71_A	0.594	0.31
658_L	862_L	0.593	0.31
128_D	264_L	0.593	0.31
937_Q	983_E	0.593	0.31
397_A	401_E	0.593	0.31
509_R	542_Y	0.593	0.31
964_E	983_E	0.592	0.31
401_E	469_E	0.592	0.31
452_T	613_Y	0.591	0.31
262_Q	525_D	0.591	0.31
971_H	974_L	0.591	0.31
955_H	961_S	0.590	0.31
591_E	760_I	0.590	0.31
559_L	631_I	0.589	0.31
361_P	579_V	0.589	0.31
394_Q	563_S	0.589	0.31
474_E	695_E	0.589	0.31
415_L	420_L	0.588	0.31
342_T	530_E	0.588	0.31
752_G	769_P	0.588	0.31
143_V	210_I	0.588	0.31
849_V	854_M	0.588	0.31
262_Q	347_E	0.588	0.31
888_S	892_I	0.588	0.31
100_V	104_E	0.588	0.31
724_V	738_D	0.587	0.31
560_I	723_I	0.587	0.31
379_T	752_G	0.586	0.31
943_V	1016_S	0.586	0.31
258_D	338_L	0.585	0.31
272_I	299_V	0.585	0.31
283_I	628_Q	0.585	0.31
765_E	811_R	0.585	0.31
361_P	897_V	0.584	0.31
234_M	892_I	0.584	0.31
982_K	987_A	0.584	0.31
428_D	658_L	0.584	0.31
218_Y	234_M	0.584	0.31
423_L	865_A	0.583	0.30
293_Q	397_A	0.583	0.30
152_E	189_T	0.583	0.30
173_T	199_S	0.583	0.30
89_N	258_D	0.582	0.30
299_V	566_I	0.582	0.30
764_E	816_K	0.582	0.30
452_T	590_F	0.582	0.30
802_M	897_V	0.582	0.30
73_S	926_R	0.582	0.30
924_Y	1003_A	0.582	0.30
520_S	545_E	0.582	0.30
230_T	269_L	0.582	0.30
240_V	378_A	0.582	0.30
167_I	267_A	0.582	0.30
772_T	787_A	0.581	0.30
391_A	855_I	0.581	0.30
584_T	670_D	0.581	0.30
36_A	83_P	0.581	0.30
338_L	606_Y	0.581	0.30
494_D	542_Y	0.581	0.30
128_D	131_K	0.581	0.30
166_V	597_N	0.581	0.30
852_V	861_L	0.581	0.30
296_V	607_E	0.580	0.30
24_A	361_P	0.580	0.30
724_V	913_A	0.580	0.30
856_P	860_R	0.579	0.30
483_L	517_I	0.579	0.30
963_M	968_N	0.579	0.30
794_I	799_Q	0.579	0.30
262_Q	535_T	0.578	0.30
966_E	1006_Q	0.578	0.30
2_P	7_I	0.578	0.30
149_V	425_I	0.578	0.30
936_L	948_E	0.577	0.30
990_H	998_E	0.577	0.30
248_I	384_A	0.577	0.30
680_E	764_E	0.577	0.30
379_T	892_I	0.576	0.30
234_M	281_C	0.576	0.30
470_N	474_E	0.576	0.30
795_T	830_I	0.575	0.30
946_L	970_L	0.575	0.30
525_D	535_T	0.575	0.30
162_I	166_V	0.574	0.30
227_T	525_D	0.574	0.30
216_I	287_L	0.573	0.30
265_R	531_F	0.573	0.30
5_T	550_I	0.573	0.30
1_M	329_Y	0.573	0.30
7_I	323_A	0.572	0.30
436_M	597_N	0.572	0.30
114_K	119_S	0.572	0.30
636_V	665_L	0.572	0.30
141_Q	379_T	0.571	0.30
983_E	990_H	0.571	0.30
98_L	107_V	0.571	0.30
771_Y	791_G	0.571	0.30
85_G	266_T	0.570	0.29
588_L	859_T	0.570	0.29
716_I	889_S	0.570	0.29
557_R	629_E	0.570	0.29
90_L	487_A	0.570	0.29
130_E	207_E	0.570	0.29
141_Q	275_L	0.570	0.29
193_K	866_S	0.569	0.29
141_Q	234_M	0.569	0.29
38_K	726_S	0.568	0.29
17_P	22_Q	0.568	0.29
704_I	708_V	0.568	0.29
339_T	531_F	0.568	0.29
139_L	213_F	0.567	0.29
45_I	649_A	0.567	0.29
201_I	360_W	0.566	0.29
710_I	720_G	0.566	0.29
833_L	917_N	0.566	0.29
498_A	517_I	0.566	0.29
225_N	801_G	0.566	0.29
120_V	329_Y	0.565	0.29
133_R	773_E	0.565	0.29
210_I	296_V	0.565	0.29
15_S	1008_G	0.564	0.29
357_F	397_A	0.564	0.29
668_L	759_L	0.564	0.29
227_T	347_E	0.564	0.29
294_Y	566_I	0.564	0.29
203_Q	264_L	0.564	0.29
346_F	527_C	0.563	0.29
750_V	819_M	0.563	0.29
100_V	833_L	0.563	0.29
421_W	559_L	0.563	0.29
509_R	512_R	0.563	0.29
336_N	346_F	0.563	0.29
75_T	116_L	0.563	0.29
254_Q	353_V	0.562	0.29
267_A	270_T	0.562	0.29
540_S	608_I	0.561	0.29
656_T	862_L	0.561	0.29
467_K	470_N	0.561	0.29
516_G	680_E	0.561	0.29
657_L	662_F	0.561	0.29
828_G	947_A	0.560	0.29
800_Q	807_Q	0.560	0.29
421_W	425_I	0.560	0.29
512_R	517_I	0.560	0.29
112_G	257_T	0.559	0.29
487_A	742_Y	0.559	0.29
887_F	904_K	0.558	0.29
966_E	1016_S	0.558	0.29
626_A	631_I	0.558	0.29
578_A	607_E	0.558	0.29
752_G	888_S	0.557	0.29
651_E	673_Q	0.557	0.29
525_D	528_A	0.557	0.29
648_E	662_F	0.557	0.29
651_E	661_S	0.557	0.29
519_P	621_H	0.557	0.29
538_F	550_I	0.557	0.29
133_R	210_I	0.557	0.29
425_I	451_K	0.556	0.28
560_I	582_V	0.556	0.28
3_K	42_Y	0.556	0.28
216_I	249_V	0.556	0.28
110_E	224_S	0.556	0.28
272_I	536_N	0.556	0.28
897_V	1022_K	0.555	0.28
939_V	942_D	0.554	0.28
696_E	699_S	0.554	0.28
1009_S	1014_P	0.554	0.28
194_Q	375_K	0.554	0.28
78_I	112_G	0.554	0.28
233_N	281_C	0.554	0.28
143_V	221_M	0.554	0.28
145_E	295_Y	0.554	0.28
342_T	526_T	0.554	0.28
115_L	133_R	0.553	0.28
752_G	787_A	0.553	0.28
242_V	989_T	0.553	0.28
248_I	462_F	0.553	0.28
999_E	1004_F	0.552	0.28
694_K	698_A	0.552	0.28
445_I	456_P	0.552	0.28
227_T	336_N	0.551	0.28
47_V	78_I	0.551	0.28
533_A	881_A	0.550	0.28
338_L	347_E	0.549	0.28
988_M	991_G	0.549	0.28
268_S	729_Q	0.549	0.28
67_E	81_E	0.549	0.28
756_E	849_V	0.549	0.28
663_Q	666_D	0.549	0.28
336_N	529_A	0.548	0.28
226_N	272_I	0.548	0.28
57_D	67_E	0.548	0.28
294_Y	299_V	0.548	0.28
355_V	389_L	0.548	0.28
136_M	167_I	0.547	0.28
90_L	788_I	0.547	0.28
346_F	533_A	0.547	0.28
189_T	682_G	0.547	0.28
87_L	99_A	0.547	0.28
988_M	994_V	0.546	0.28
378_A	769_P	0.546	0.28
827_N	975_S	0.546	0.28
57_D	362_F	0.546	0.28
993_P	996_T	0.546	0.28
928_W	931_K	0.546	0.28
321_M	655_I	0.546	0.28
527_C	535_T	0.545	0.28
668_L	686_A	0.545	0.28
262_Q	266_T	0.545	0.28
579_V	904_K	0.545	0.28
254_Q	375_K	0.544	0.28
646_A	791_G	0.544	0.28
775_I	946_L	0.544	0.28
90_L	524_V	0.544	0.28
723_I	734_L	0.544	0.28
90_L	538_F	0.544	0.28
766_V	804_D	0.544	0.28
149_V	156_L	0.543	0.28
261_Y	350_L	0.543	0.28
664_T	812_K	0.542	0.28
388_N	541_T	0.542	0.28
786_F	920_L	0.542	0.28
749_Y	917_N	0.541	0.27
486_K	490_K	0.541	0.27
206_V	448_I	0.541	0.27
144_P	164_F	0.540	0.27
465_I	655_I	0.540	0.27
407_T	430_R	0.540	0.27
258_D	530_E	0.540	0.27
668_L	716_I	0.539	0.27
801_G	828_G	0.537	0.27
984_R	987_A	0.537	0.27
403_K	406_G	0.537	0.27
280_G	303_V	0.537	0.27
413_S	502_S	0.537	0.27
35_I	608_I	0.536	0.27
772_T	789_L	0.536	0.27
752_G	920_L	0.536	0.27
706_Y	768_I	0.535	0.27
214_K	526_T	0.535	0.27
493_S	517_I	0.535	0.27
393_I	472_L	0.535	0.27
228_C	577_S	0.535	0.27
273_S	387_R	0.534	0.27
95_A	578_A	0.534	0.27
156_L	160_E	0.534	0.27
227_T	346_F	0.534	0.27
761_S	853_P	0.534	0.27
122_T	635_I	0.533	0.27
419_T	423_L	0.533	0.27
1_M	333_E	0.532	0.27
699_S	972_I	0.532	0.27
992_I	1019_D	0.532	0.27
115_L	120_V	0.532	0.27
808_K	839_A	0.532	0.27
989_T	998_E	0.532	0.27
104_E	259_E	0.532	0.27
947_A	971_H	0.532	0.27
211_A	240_V	0.531	0.27
488_K	512_R	0.531	0.27
229_I	272_I	0.531	0.27
43_R	254_Q	0.531	0.27
79_K	953_T	0.531	0.27
226_N	283_I	0.531	0.27
234_M	361_P	0.531	0.27
213_F	457_F	0.530	0.27
398_A	617_M	0.530	0.27
440_S	496_T	0.530	0.27
404_N	409_L	0.530	0.27
36_A	323_A	0.530	0.27
375_K	923_I	0.530	0.27
424_A	448_I	0.529	0.27
240_V	990_H	0.529	0.27
258_D	527_C	0.529	0.27
506_E	510_A	0.528	0.27
254_Q	433_F	0.528	0.27
181_I	211_A	0.528	0.27
2_P	6_S	0.528	0.27
152_E	196_L	0.528	0.27
113_V	271_I	0.528	0.27
186_E	450_E	0.528	0.27
204_C	211_A	0.528	0.27
468_L	472_L	0.528	0.27
1006_Q	1018_K	0.527	0.26
45_I	63_E	0.527	0.26
82_R	663_Q	0.526	0.26
237_I	254_Q	0.526	0.26
435_V	439_L	0.525	0.26
691_A	755_V	0.525	0.26
67_E	108_L	0.525	0.26
552_R	555_K	0.525	0.26
72_E	731_S	0.524	0.26
171_A	179_G	0.524	0.26
850_M	875_Q	0.524	0.26
585_L	635_I	0.524	0.26
985_L	1017_L	0.524	0.26
795_T	827_N	0.523	0.26
595_I	1002_R	0.523	0.26
7_I	486_K	0.522	0.26
833_L	859_T	0.522	0.26
702_S	811_R	0.522	0.26
258_D	346_F	0.522	0.26
59_A	853_P	0.522	0.26
415_L	441_R	0.522	0.26
64_I	277_V	0.521	0.26
126_G	664_T	0.521	0.26
258_D	535_T	0.521	0.26
827_N	974_L	0.521	0.26
421_W	424_A	0.521	0.26
772_T	785_S	0.521	0.26
110_E	161_S	0.520	0.26
382_V	400_L	0.520	0.26
256_L	455_D	0.520	0.26
80_K	775_I	0.520	0.26
239_P	493_S	0.520	0.26
759_L	766_V	0.520	0.26
993_P	997_E	0.520	0.26
100_V	254_Q	0.520	0.26
428_D	912_V	0.519	0.26
990_H	1016_S	0.519	0.26
552_R	557_R	0.519	0.26
120_V	124_Q	0.519	0.26
59_A	587_E	0.519	0.26
525_D	533_A	0.519	0.26
527_C	530_E	0.519	0.26
179_G	375_K	0.518	0.26
645_N	819_M	0.518	0.26
339_T	530_E	0.518	0.26
685_H	688_G	0.518	0.26
342_T	347_E	0.518	0.26
229_I	283_I	0.518	0.26
943_V	967_G	0.518	0.26
54_I	678_L	0.517	0.26
213_F	288_D	0.517	0.26
446_D	635_I	0.517	0.26
336_N	533_A	0.517	0.26
969_S	974_L	0.517	0.26
550_I	553_K	0.516	0.26
263_M	291_S	0.516	0.26
278_V	281_C	0.516	0.26
608_I	833_L	0.516	0.26
98_L	708_V	0.516	0.26
606_Y	898_K	0.515	0.26
2_P	329_Y	0.515	0.26
678_L	683_L	0.515	0.26
728_A	865_A	0.515	0.26
44_V	246_D	0.515	0.26
227_T	529_A	0.515	0.26
1008_G	1012_P	0.515	0.26
152_E	206_V	0.515	0.26
179_G	203_Q	0.514	0.26
566_I	688_G	0.514	0.26
855_I	918_S	0.514	0.26
11_L	115_L	0.514	0.26
314_T	778_A	0.514	0.26
706_Y	709_L	0.513	0.26
140_K	153_A	0.513	0.26
133_R	487_A	0.513	0.26
737_E	909_G	0.513	0.26
509_R	516_G	0.512	0.25
803_K	875_Q	0.512	0.25
444_S	449_H	0.512	0.25
337_P	343_Y	0.512	0.25
196_L	932_G	0.512	0.25
121_E	124_Q	0.511	0.25
527_C	536_N	0.511	0.25
495_A	541_T	0.511	0.25
519_P	825_I	0.511	0.25
963_M	966_E	0.511	0.25
361_P	885_P	0.511	0.25
419_T	422_D	0.511	0.25
965_Q	982_K	0.511	0.25
261_Y	347_E	0.510	0.25
771_Y	802_M	0.510	0.25
338_L	536_N	0.510	0.25
1006_Q	1016_S	0.509	0.25
739_S	742_Y	0.509	0.25
471_R	625_V	0.509	0.25
110_E	931_K	0.509	0.25
808_K	811_R	0.509	0.25
90_L	523_I	0.509	0.25
17_P	49_S	0.509	0.25
662_F	846_V	0.508	0.25
82_R	800_Q	0.508	0.25
996_T	1004_F	0.508	0.25
525_D	530_E	0.508	0.25
584_T	588_L	0.508	0.25
480_S	511_L	0.507	0.25
75_T	86_L	0.507	0.25
617_M	621_H	0.506	0.25
166_V	207_E	0.506	0.25
44_V	524_V	0.506	0.25
538_F	788_I	0.506	0.25
882_V	919_A	0.506	0.25
261_Y	530_E	0.506	0.25
846_V	854_M	0.506	0.25
142_P	370_R	0.505	0.25
168_I	961_S	0.505	0.25
983_E	991_G	0.505	0.25
242_V	452_T	0.505	0.25
83_P	833_L	0.505	0.25
741_P	744_I	0.505	0.25
452_T	830_I	0.505	0.25
645_N	788_I	0.504	0.25
4_D	327_V	0.504	0.25
724_V	971_H	0.504	0.25
422_D	444_S	0.504	0.25
439_L	970_L	0.503	0.25
10_I	213_F	0.503	0.25
24_A	597_N	0.503	0.25
141_Q	363_D	0.503	0.25
552_R	593_I	0.502	0.25
897_V	1018_K	0.502	0.25
7_I	768_I	0.502	0.25
204_C	428_D	0.502	0.25
786_F	923_I	0.502	0.25
571_G	717_G	0.501	0.25
623_V	634_A	0.501	0.25
194_Q	619_T	0.501	0.25
181_I	209_S	0.501	0.25
172_Y	228_C	0.501	0.25
340_G	465_I	0.501	0.25
340_G	977_S	0.501	0.25
626_A	650_L	0.501	0.25
10_I	444_S	0.500	0.25
389_L	393_I	0.500	0.25
3_K	7_I	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1a9xA	3	0.9835	100	0.41	Contact Map
3jrxA	1	0.399	100	0.894	Contact Map
3glkA	1	0.3777	100	0.895	Contact Map
3orqA	2	0.3505	100	0.896	Contact Map
2vpqA	2	0.4019	100	0.898	Contact Map
1ulzA	2	0.4078	100	0.898	Contact Map
2dzdA	2	0.4019	100	0.901	Contact Map
1w96A	1	0.4049	100	0.902	Contact Map
3q2oA	2	0.3515	100	0.903	Contact Map
2dwcA	4	0.3621	100	0.905	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0226 seconds.