GLPD - BACSU - GREMLIN Contacts

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GLPD - Aerobic glycerol-3-phosphate dehydrogenase

UniProt:	P18158	Sequences: MMNHQFSSLERDRMLTDMTKKTYDLFIIGGGITGAGTALDAASRGMKVALSEMQDFAAGTSSRSTKLVHGGLRYLKQFEVKMVAEVGKERAIVYENGPHVTTPEWMLLPFHKGGTFGSFTTSIGLRVYDFLAGVKKSERRSMLSAKETLQKEPLVKKDGLKGGGYYVEYRTDDARLTIEVMKEAVKFGAEPVNYSKVKELLYEKGKAVGVLIEDVLTKKEYKVYAKKIVNATGPWVDQLREKDHSKNGKHLQHTKGIHLVFDQSVFPLKQAVYFDTPDGRMVFAIPREGKTYVGTTDTVYKEALEHPRMTTEDRDYVIKSINYMFPELNITANDIESSWAGLRPLIHEEGKDPSEISRKDEIWTSDSGLITIAGGKLTGYRKMAEHIVDLVRDRLKEEGEKDFGPCKTKNMPISGGHVGGSKNLMSFVTAKTKEGIAAGLSEKDAKQLAIRYGSNVDRVFDRVEALKDEAAKRNIPVHILAEAEYSIEEEMTATPADFFVRRTGRLFFDINWVRTYKDAVIDFMSERFQWDEQAKNKHTENLNKLLHDAVVPLEQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	555 (491)
Sequences:	3250 (2025)
Seq/√Len:	91.4

ECOLI - GLPA GLPD
BACSU - GLPD
HALSA - Q9HNS4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
26_F	210_V	5.712	1.00
23_Y	49_A	4.233	1.00
148_T	163_G	4.118	1.00
213_E	220_E	4.008	1.00
53_M	196_K	3.783	1.00
51_S	212_I	3.692	1.00
261_F	293_V	3.636	1.00
51_S	197_V	3.625	1.00
311_T	332_A	3.588	1.00
184_A	189_A	3.558	1.00
212_I	223_V	3.406	1.00
315_D	319_K	3.256	1.00
196_K	213_E	3.241	1.00
195_S	212_I	3.179	1.00
54_Q	58_A	3.165	1.00
211_L	220_E	3.054	1.00
36_G	380_Y	3.043	1.00
257_I	317_V	3.040	1.00
56_F	193_N	3.021	1.00
26_F	225_A	2.991	1.00
198_K	213_E	2.963	1.00
196_K	215_V	2.910	1.00
315_D	332_A	2.903	1.00
229_V	391_V	2.901	1.00
216_L	493_A	2.856	1.00
492_T	498_F	2.851	1.00
211_L	222_K	2.757	1.00
22_T	226_K	2.738	1.00
23_Y	190_E	2.725	1.00
26_F	223_V	2.693	1.00
35_A	181_M	2.672	1.00
19_T	219_K	2.669	1.00
199_E	211_L	2.591	1.00
458_R	489_E	2.406	1.00
480_L	484_E	2.403	1.00
26_F	49_A	2.345	1.00
51_S	210_V	2.334	1.00
214_D	217_T	2.322	1.00
322_N	330_I	2.279	1.00
49_A	223_V	2.202	1.00
181_M	191_P	2.199	1.00
252_Q	299_V	2.182	1.00
483_A	498_F	2.164	1.00
22_T	224_Y	2.151	1.00
185_V	191_P	2.149	1.00
28_I	239_L	2.144	1.00
311_T	315_D	2.140	1.00
32_I	180_V	2.111	1.00
455_N	485_Y	2.093	1.00
451_R	503_T	2.088	1.00
232_T	239_L	2.081	1.00
30_G	50_L	2.066	1.00
182_K	455_N	2.039	1.00
53_M	305_E	2.011	1.00
37_T	388_V	1.991	1.00
38_A	48_V	1.988	1.00
30_G	52_E	1.951	1.00
201_L	222_K	1.946	1.00
318_I	330_I	1.940	1.00
207_A	228_I	1.928	1.00
21_K	47_K	1.894	1.00
263_Q	289_G	1.891	1.00
471_A	480_L	1.889	1.00
480_L	519_A	1.886	1.00
25_L	227_K	1.882	1.00
201_L	209_G	1.858	1.00
40_D	408_T	1.836	1.00
43_S	407_K	1.822	1.00
200_L	228_I	1.809	1.00
314_R	332_A	1.807	1.00
309_M	338_S	1.779	1.00
26_F	51_S	1.774	1.00
309_M	314_R	1.752	1.00
364_T	394_R	1.745	1.00
201_L	208_V	1.742	1.00
27_I	37_T	1.729	1.00
56_F	181_M	1.725	1.00
284_A	291_T	1.717	1.00
370_I	391_V	1.710	1.00
186_K	455_N	1.705	1.00
487_I	524_M	1.696	1.00
483_A	517_K	1.688	1.00
202_Y	205_G	1.685	1.00
33_T	372_I	1.671	1.00
39_L	183_E	1.649	1.00
332_A	335_I	1.640	1.00
486_S	498_F	1.636	1.00
486_S	492_T	1.636	1.00
243_D	365_S	1.635	1.00
43_S	411_M	1.611	1.00
35_A	177_T	1.609	1.00
57_A	174_A	1.599	1.00
255_K	298_T	1.599	1.00
436_I	457_D	1.591	1.00
318_I	332_A	1.590	1.00
198_K	211_L	1.579	1.00
314_R	338_S	1.576	1.00
459_V	481_A	1.573	1.00
111_H	160_L	1.570	1.00
500_V	506_L	1.563	1.00
40_D	44_R	1.553	1.00
200_L	239_L	1.546	1.00
192_V	221_Y	1.535	1.00
236_V	251_L	1.526	1.00
105_W	167_V	1.520	1.00
318_I	322_N	1.519	1.00
227_K	391_V	1.512	1.00
149_L	157_K	1.491	1.00
495_P	521_I	1.489	1.00
172_D	451_R	1.488	1.00
203_E	209_G	1.481	1.00
284_A	321_I	1.480	1.00
255_K	300_Y	1.472	1.00
390_L	393_D	1.469	1.00
56_F	191_P	1.469	1.00
43_S	187_F	1.467	1.00
198_K	220_E	1.465	1.00
441_S	444_D	1.465	1.00
39_L	180_V	1.449	0.99
463_V	470_A	1.441	0.99
257_I	298_T	1.438	0.99
462_R	484_E	1.434	0.99
49_A	192_V	1.430	0.99
322_N	329_N	1.420	0.99
65_T	285_I	1.420	0.99
239_L	242_K	1.415	0.99
147_E	150_Q	1.400	0.99
472_K	476_P	1.392	0.99
472_K	479_I	1.380	0.99
141_S	165_Y	1.378	0.99
321_I	330_I	1.374	0.99
183_E	187_F	1.373	0.99
195_S	221_Y	1.352	0.99
147_E	151_K	1.345	0.99
300_Y	303_A	1.340	0.99
176_L	377_L	1.331	0.99
424_L	428_V	1.325	0.99
180_V	380_Y	1.316	0.99
471_A	516_Y	1.315	0.99
101_T	169_Y	1.308	0.99
213_E	218_K	1.306	0.99
145_A	149_L	1.305	0.99
59_G	63_R	1.291	0.99
519_A	522_D	1.286	0.99
102_T	170_R	1.284	0.99
252_Q	347_H	1.277	0.99
192_V	195_S	1.276	0.99
262_D	290_K	1.269	0.99
40_D	406_C	1.269	0.99
255_K	310_T	1.263	0.99
85_E	382_K	1.261	0.99
227_K	395_L	1.252	0.98
81_K	85_E	1.250	0.98
458_R	461_D	1.250	0.98
84_A	88_K	1.245	0.98
484_E	523_F	1.245	0.98
46_M	392_R	1.243	0.98
23_Y	47_K	1.240	0.98
274_F	284_A	1.237	0.98
93_V	101_T	1.224	0.98
38_A	189_A	1.219	0.98
144_S	147_E	1.218	0.98
500_V	507_F	1.216	0.98
511_N	515_T	1.215	0.98
292_Y	339_W	1.213	0.98
183_E	186_K	1.212	0.98
158_D	326_P	1.212	0.98
451_R	482_E	1.199	0.98
259_L	293_V	1.189	0.98
143_L	148_T	1.186	0.98
38_A	184_A	1.185	0.98
277_P	323_Y	1.184	0.98
260_V	337_S	1.178	0.98
51_S	223_V	1.173	0.98
105_W	165_Y	1.164	0.98
74_Y	376_K	1.161	0.98
54_Q	59_G	1.160	0.98
199_E	242_K	1.158	0.97
510_I	513_V	1.156	0.97
37_T	229_V	1.155	0.97
42_A	48_V	1.151	0.97
417_H	454_S	1.151	0.97
234_P	342_L	1.146	0.97
212_I	221_Y	1.141	0.97
384_A	406_C	1.139	0.97
102_T	450_I	1.132	0.97
54_Q	194_Y	1.127	0.97
498_F	520_V	1.124	0.97
499_F	514_R	1.120	0.97
194_Y	493_A	1.119	0.97
41_A	388_V	1.116	0.97
181_M	193_N	1.112	0.97
40_D	384_A	1.111	0.97
151_K	154_L	1.111	0.97
518_D	522_D	1.109	0.97
77_Q	355_E	1.106	0.97
201_L	211_L	1.106	0.97
200_L	242_K	1.105	0.97
26_F	228_I	1.103	0.97
25_L	41_A	1.103	0.97
79_E	82_M	1.095	0.96
51_S	195_S	1.089	0.96
231_A	372_I	1.089	0.96
24_D	226_K	1.077	0.96
420_G	423_N	1.076	0.96
22_T	207_A	1.070	0.96
310_T	313_D	1.068	0.96
474_N	477_V	1.058	0.96
389_D	406_C	1.055	0.96
326_P	329_N	1.052	0.96
362_I	386_H	1.042	0.95
412_P	416_G	1.036	0.95
187_F	411_M	1.035	0.95
67_L	170_R	1.034	0.95
115_T	118_S	1.027	0.95
97_G	413_I	1.020	0.95
116_F	120_T	1.020	0.95
57_A	177_T	1.018	0.95
303_A	306_H	1.016	0.95
47_K	190_E	1.005	0.94
392_R	395_L	1.004	0.94
24_D	46_M	1.004	0.94
364_T	370_I	1.003	0.94
522_D	526_E	1.001	0.94
209_G	224_Y	0.997	0.94
370_I	390_L	0.995	0.94
114_G	117_G	0.994	0.94
448_L	459_V	0.993	0.94
390_L	394_R	0.993	0.94
346_I	361_E	0.988	0.94
265_V	334_D	0.986	0.94
93_V	176_L	0.985	0.94
364_T	390_L	0.984	0.94
300_Y	342_L	0.983	0.94
442_E	446_K	0.980	0.94
104_E	170_R	0.979	0.93
19_T	221_Y	0.976	0.93
385_E	409_K	0.974	0.93
113_G	116_F	0.973	0.93
256_G	343_R	0.966	0.93
177_T	377_L	0.965	0.93
203_E	208_V	0.960	0.93
203_E	224_Y	0.959	0.93
210_V	225_A	0.959	0.93
179_E	413_I	0.958	0.93
142_M	162_G	0.957	0.93
56_F	491_M	0.954	0.93
69_H	73_R	0.952	0.92
484_E	488_E	0.952	0.92
73_R	295_T	0.951	0.92
73_R	376_K	0.943	0.92
197_V	210_V	0.939	0.92
427_F	449_A	0.938	0.92
265_V	284_A	0.936	0.92
385_E	389_D	0.935	0.92
483_A	520_V	0.933	0.92
227_K	394_R	0.930	0.92
392_R	397_E	0.928	0.92
348_E	356_I	0.928	0.92
149_L	155_V	0.924	0.91
296_T	343_R	0.923	0.91
360_D	386_H	0.921	0.91
100_V	179_E	0.912	0.91
404_G	407_K	0.909	0.91
23_Y	26_F	0.907	0.91
263_Q	269_K	0.906	0.91
273_Y	281_M	0.900	0.90
83_V	128_Y	0.899	0.90
182_K	185_V	0.894	0.90
126_R	140_R	0.893	0.90
30_G	56_F	0.891	0.90
92_I	96_N	0.890	0.90
385_E	406_C	0.889	0.90
509_D	513_V	0.889	0.90
27_I	39_L	0.886	0.90
33_T	383_M	0.885	0.89
517_K	521_I	0.883	0.89
117_G	120_T	0.881	0.89
68_V	93_V	0.880	0.89
473_R	476_P	0.880	0.89
114_G	118_S	0.879	0.89
46_M	396_K	0.879	0.89
82_M	86_V	0.876	0.89
345_L	376_K	0.876	0.89
343_R	358_R	0.875	0.89
293_V	321_I	0.875	0.89
262_D	336_E	0.874	0.89
88_K	382_K	0.871	0.89
282_V	320_S	0.871	0.89
258_H	297_D	0.870	0.89
462_R	488_E	0.869	0.89
227_K	370_I	0.862	0.88
299_V	356_I	0.859	0.88
521_I	525_S	0.858	0.88
41_A	48_V	0.851	0.88
485_Y	489_E	0.851	0.88
37_T	231_A	0.850	0.88
258_H	296_T	0.845	0.87
199_E	220_E	0.845	0.87
370_I	387_I	0.844	0.87
83_V	345_L	0.843	0.87
85_E	359_K	0.843	0.87
256_G	296_T	0.841	0.87
209_G	222_K	0.840	0.87
260_V	292_Y	0.836	0.87
463_V	481_A	0.834	0.87
200_L	210_V	0.834	0.87
283_F	295_T	0.832	0.86
424_L	427_F	0.830	0.86
480_L	523_F	0.829	0.86
298_T	313_D	0.828	0.86
476_P	505_R	0.828	0.86
38_A	191_P	0.827	0.86
96_N	412_P	0.827	0.86
22_T	47_K	0.827	0.86
499_F	520_V	0.826	0.86
355_E	361_E	0.826	0.86
144_S	148_T	0.825	0.86
79_E	359_K	0.824	0.86
95_E	410_N	0.823	0.86
461_D	464_E	0.823	0.86
85_E	386_H	0.821	0.86
462_R	481_A	0.820	0.86
89_E	381_R	0.819	0.86
296_T	376_K	0.818	0.85
37_T	384_A	0.817	0.85
163_G	273_Y	0.816	0.85
495_P	499_F	0.814	0.85
36_G	384_A	0.811	0.85
446_K	450_I	0.808	0.85
237_D	240_R	0.805	0.85
43_S	183_E	0.802	0.84
99_H	416_G	0.802	0.84
440_L	445_A	0.799	0.84
309_M	335_I	0.799	0.84
243_D	367_S	0.799	0.84
466_L	469_E	0.798	0.84
183_E	417_H	0.798	0.84
472_K	483_A	0.794	0.84
484_E	520_V	0.793	0.84
60_T	234_P	0.792	0.84
214_D	219_K	0.791	0.83
44_R	408_T	0.791	0.83
444_D	479_I	0.789	0.83
448_L	479_I	0.786	0.83
217_T	220_E	0.785	0.83
467_K	471_A	0.785	0.83
478_H	482_E	0.784	0.83
50_L	56_F	0.784	0.83
25_L	229_V	0.783	0.83
265_V	330_I	0.782	0.83
448_L	456_V	0.779	0.83
241_E	244_H	0.779	0.83
195_S	223_V	0.776	0.82
256_G	376_K	0.776	0.82
277_P	320_S	0.775	0.82
95_E	136_K	0.775	0.82
427_F	457_D	0.774	0.82
478_H	503_T	0.774	0.82
126_R	139_R	0.773	0.82
480_L	520_V	0.772	0.82
382_K	386_H	0.772	0.82
343_R	376_K	0.772	0.82
83_V	87_G	0.771	0.82
40_D	389_D	0.770	0.82
264_S	327_E	0.769	0.82
290_K	336_E	0.769	0.82
31_G	34_G	0.768	0.82
165_Y	168_E	0.766	0.81
172_D	288_E	0.766	0.81
372_I	383_M	0.765	0.81
71_G	74_Y	0.765	0.81
296_T	358_R	0.765	0.81
289_G	508_F	0.763	0.81
184_A	191_P	0.760	0.81
319_K	323_Y	0.760	0.81
388_V	406_C	0.758	0.81
216_L	219_K	0.757	0.81
499_F	517_K	0.756	0.81
261_F	330_I	0.756	0.81
111_H	155_V	0.755	0.81
98_P	416_G	0.754	0.80
313_D	359_K	0.753	0.80
184_A	384_A	0.753	0.80
107_L	163_G	0.750	0.80
262_D	289_G	0.745	0.80
84_A	409_K	0.745	0.80
473_R	512_W	0.745	0.80
94_Y	101_T	0.744	0.80
447_Q	482_E	0.743	0.79
74_Y	256_G	0.743	0.79
25_L	388_V	0.740	0.79
391_V	395_L	0.740	0.79
36_G	40_D	0.738	0.79
28_I	197_V	0.737	0.79
459_V	463_V	0.735	0.79
481_A	484_E	0.733	0.79
256_G	345_L	0.732	0.78
297_D	376_K	0.731	0.78
385_E	408_T	0.730	0.78
463_V	467_K	0.730	0.78
274_F	330_I	0.727	0.78
465_A	468_D	0.727	0.78
209_G	225_A	0.726	0.78
49_A	212_I	0.726	0.78
456_V	460_F	0.725	0.78
236_V	371_T	0.724	0.78
113_G	377_L	0.722	0.78
358_R	376_K	0.722	0.78
27_I	243_D	0.722	0.78
304_L	307_P	0.720	0.77
146_K	150_Q	0.719	0.77
40_D	385_E	0.719	0.77
381_R	408_T	0.718	0.77
380_Y	408_T	0.717	0.77
255_K	340_A	0.717	0.77
447_Q	478_H	0.715	0.77
110_F	115_T	0.715	0.77
445_A	456_V	0.712	0.77
461_D	465_A	0.712	0.77
200_L	207_A	0.711	0.76
148_T	155_V	0.709	0.76
27_I	388_V	0.709	0.76
215_V	219_K	0.709	0.76
266_F	291_T	0.706	0.76
186_K	414_S	0.706	0.76
395_L	398_E	0.705	0.76
344_P	376_K	0.705	0.76
71_G	376_K	0.704	0.76
111_H	159_G	0.704	0.76
99_H	415_G	0.702	0.76
210_V	223_V	0.702	0.76
35_A	191_P	0.701	0.75
343_R	375_G	0.700	0.75
512_W	515_T	0.699	0.75
120_T	123_I	0.698	0.75
128_Y	166_Y	0.697	0.75
64_S	173_D	0.697	0.75
216_L	494_T	0.695	0.75
103_P	167_V	0.694	0.75
96_N	380_Y	0.693	0.75
106_M	271_A	0.690	0.74
86_V	379_G	0.690	0.74
466_L	470_A	0.689	0.74
472_K	513_V	0.688	0.74
70_G	75_L	0.687	0.74
197_V	239_L	0.687	0.74
516_Y	520_V	0.686	0.74
213_E	219_K	0.684	0.74
256_G	341_G	0.684	0.74
427_F	430_A	0.682	0.73
362_I	387_I	0.681	0.73
39_L	43_S	0.678	0.73
24_D	47_K	0.678	0.73
185_V	491_M	0.677	0.73
213_E	217_T	0.676	0.73
468_D	471_A	0.676	0.73
23_Y	223_V	0.675	0.73
201_L	224_Y	0.674	0.73
276_T	320_S	0.674	0.73
160_L	163_G	0.673	0.72
62_S	173_D	0.672	0.72
462_R	489_E	0.669	0.72
240_R	369_L	0.667	0.72
463_V	469_E	0.667	0.72
81_K	359_K	0.665	0.72
261_F	322_N	0.665	0.72
391_V	396_K	0.664	0.71
95_E	135_K	0.664	0.71
200_L	369_L	0.664	0.71
29_G	34_G	0.663	0.71
366_D	394_R	0.663	0.71
455_N	458_R	0.663	0.71
515_T	518_D	0.661	0.71
389_D	408_T	0.661	0.71
149_L	160_L	0.661	0.71
446_K	465_A	0.656	0.71
254_T	353_P	0.655	0.70
517_K	520_V	0.655	0.70
48_V	191_P	0.654	0.70
277_P	319_K	0.653	0.70
110_F	164_G	0.652	0.70
126_R	130_F	0.651	0.70
68_V	97_G	0.649	0.70
112_K	117_G	0.649	0.70
345_L	358_R	0.647	0.69
85_E	108_L	0.647	0.69
60_T	71_G	0.645	0.69
143_L	165_Y	0.645	0.69
37_T	387_I	0.644	0.69
287_R	292_Y	0.643	0.69
478_H	483_A	0.642	0.69
175_R	490_E	0.642	0.69
473_R	519_A	0.642	0.69
66_K	173_D	0.640	0.69
215_V	218_K	0.638	0.68
81_K	386_H	0.636	0.68
300_Y	307_P	0.636	0.68
50_L	181_M	0.635	0.68
366_D	405_P	0.635	0.68
236_V	373_A	0.634	0.68
60_T	345_L	0.634	0.68
424_L	446_K	0.634	0.68
25_L	37_T	0.632	0.68
423_N	427_F	0.630	0.67
97_G	381_R	0.629	0.67
252_Q	356_I	0.629	0.67
230_N	371_T	0.627	0.67
282_V	321_I	0.627	0.67
67_L	124_G	0.627	0.67
268_L	274_F	0.626	0.67
237_D	250_H	0.626	0.67
179_E	414_S	0.624	0.67
41_A	46_M	0.624	0.67
187_F	407_K	0.623	0.67
100_V	377_L	0.621	0.66
259_L	314_R	0.621	0.66
208_V	224_Y	0.620	0.66
256_G	358_R	0.620	0.66
166_Y	281_M	0.618	0.66
295_T	376_K	0.618	0.66
271_A	285_I	0.617	0.66
190_E	193_N	0.617	0.66
251_L	317_V	0.617	0.66
469_E	484_E	0.617	0.66
151_K	270_Q	0.616	0.66
282_V	317_V	0.615	0.66
238_Q	304_L	0.614	0.65
296_T	345_L	0.613	0.65
264_S	336_E	0.609	0.65
448_L	482_E	0.609	0.65
65_T	265_V	0.608	0.65
63_R	172_D	0.607	0.65
74_Y	343_R	0.607	0.65
441_S	445_A	0.607	0.65
168_E	171_T	0.601	0.64
75_L	83_V	0.601	0.64
80_V	116_F	0.600	0.64
414_S	455_N	0.599	0.64
254_T	299_V	0.599	0.64
67_L	285_I	0.599	0.64
200_L	209_G	0.597	0.63
48_V	189_A	0.596	0.63
199_E	245_S	0.596	0.63
44_R	406_C	0.596	0.63
429_T	498_F	0.596	0.63
293_V	317_V	0.595	0.63
181_M	185_V	0.595	0.63
254_T	345_L	0.594	0.63
172_D	504_G	0.594	0.63
309_M	313_D	0.594	0.63
276_T	282_V	0.594	0.63
195_S	198_K	0.594	0.63
74_Y	296_T	0.593	0.63
201_L	207_A	0.593	0.63
421_S	424_L	0.593	0.63
456_V	459_V	0.592	0.63
83_V	166_Y	0.592	0.63
82_M	166_Y	0.591	0.63
26_F	212_I	0.588	0.62
91_A	103_P	0.588	0.62
297_D	343_R	0.587	0.62
49_A	190_E	0.587	0.62
97_G	314_R	0.587	0.62
407_K	411_M	0.587	0.62
72_L	171_T	0.585	0.62
42_A	187_F	0.585	0.62
225_A	228_I	0.585	0.62
447_Q	452_Y	0.585	0.62
239_L	244_H	0.584	0.62
352_D	355_E	0.584	0.62
69_H	74_Y	0.583	0.61
92_I	409_K	0.583	0.61
250_H	371_T	0.582	0.61
91_A	135_K	0.582	0.61
195_S	215_V	0.582	0.61
487_I	521_I	0.581	0.61
483_A	492_T	0.580	0.61
74_Y	345_L	0.579	0.61
316_Y	325_F	0.579	0.61
132_A	136_K	0.579	0.61
77_Q	298_T	0.578	0.61
57_A	181_M	0.578	0.61
280_R	316_Y	0.578	0.61
77_Q	354_S	0.577	0.61
65_T	283_F	0.577	0.61
497_D	501_R	0.576	0.61
266_F	284_A	0.573	0.60
96_N	409_K	0.572	0.60
65_T	274_F	0.572	0.60
97_G	176_L	0.571	0.60
76_K	83_V	0.571	0.60
495_P	520_V	0.571	0.60
86_V	281_M	0.571	0.60
408_T	415_G	0.570	0.60
69_H	376_K	0.570	0.60
38_A	44_R	0.569	0.60
325_F	329_N	0.569	0.60
468_D	526_E	0.569	0.60
25_L	48_V	0.569	0.60
66_K	73_R	0.568	0.59
311_T	314_R	0.568	0.59
97_G	100_V	0.568	0.59
459_V	462_R	0.568	0.59
128_Y	132_A	0.566	0.59
459_V	479_I	0.565	0.59
32_I	72_L	0.565	0.59
505_R	512_W	0.564	0.59
55_D	501_R	0.564	0.59
313_D	379_G	0.563	0.59
495_P	517_K	0.563	0.59
90_R	378_T	0.563	0.59
216_L	372_I	0.563	0.59
87_G	287_R	0.563	0.59
463_V	479_I	0.562	0.59
280_R	376_K	0.561	0.59
219_K	410_N	0.561	0.59
268_L	284_A	0.561	0.59
256_G	297_D	0.561	0.59
237_D	241_E	0.560	0.58
61_S	173_D	0.560	0.58
111_H	114_G	0.559	0.58
183_E	414_S	0.557	0.58
257_I	335_I	0.556	0.58
74_Y	297_D	0.555	0.58
325_F	340_A	0.555	0.58
123_I	127_V	0.554	0.58
40_D	388_V	0.553	0.57
512_W	516_Y	0.552	0.57
281_M	287_R	0.552	0.57
182_K	485_Y	0.551	0.57
353_P	356_I	0.551	0.57
60_T	74_Y	0.550	0.57
499_F	507_F	0.547	0.57
47_K	224_Y	0.546	0.56
363_W	386_H	0.546	0.56
259_L	354_S	0.545	0.56
49_A	53_M	0.545	0.56
40_D	381_R	0.545	0.56
194_Y	494_T	0.544	0.56
82_M	87_G	0.544	0.56
355_E	359_K	0.543	0.56
297_D	358_R	0.542	0.56
82_M	256_G	0.541	0.56
96_N	411_M	0.541	0.56
25_L	393_D	0.541	0.56
254_T	313_D	0.540	0.56
72_L	125_L	0.540	0.56
521_I	524_M	0.540	0.56
261_F	266_F	0.540	0.56
209_G	228_I	0.540	0.56
211_L	221_Y	0.539	0.56
105_W	126_R	0.539	0.56
209_G	365_S	0.539	0.56
382_K	385_E	0.538	0.55
200_L	243_D	0.537	0.55
110_F	273_Y	0.536	0.55
370_I	394_R	0.536	0.55
151_K	165_Y	0.534	0.55
161_K	165_Y	0.534	0.55
451_R	505_R	0.534	0.55
40_D	380_Y	0.534	0.55
280_R	283_F	0.534	0.55
76_K	342_L	0.533	0.55
380_Y	413_I	0.533	0.55
297_D	345_L	0.533	0.55
159_G	162_G	0.530	0.54
64_S	295_T	0.529	0.54
115_T	275_D	0.529	0.54
60_T	376_K	0.528	0.54
41_A	100_V	0.527	0.54
44_R	381_R	0.527	0.54
281_M	339_W	0.527	0.54
284_A	320_S	0.526	0.54
107_L	255_K	0.526	0.54
484_E	526_E	0.525	0.54
88_K	133_G	0.525	0.54
469_E	481_A	0.525	0.54
420_G	424_L	0.524	0.53
171_T	377_L	0.524	0.53
26_F	192_V	0.524	0.53
469_E	480_L	0.524	0.53
156_K	159_G	0.522	0.53
148_T	160_L	0.522	0.53
484_E	487_I	0.521	0.53
217_T	493_A	0.520	0.53
363_W	371_T	0.519	0.53
30_G	34_G	0.519	0.53
312_E	315_D	0.519	0.53
77_Q	357_S	0.519	0.53
397_E	404_G	0.518	0.53
74_Y	358_R	0.518	0.53
143_L	153_P	0.518	0.53
87_G	128_Y	0.517	0.53
416_G	454_S	0.517	0.53
49_A	224_Y	0.516	0.52
385_E	407_K	0.516	0.52
107_L	143_L	0.516	0.52
39_L	174_A	0.515	0.52
59_G	456_V	0.515	0.52
159_G	168_E	0.514	0.52
140_R	143_L	0.513	0.52
297_D	353_P	0.512	0.52
128_Y	258_H	0.512	0.52
48_V	386_H	0.512	0.52
300_Y	304_L	0.512	0.52
259_L	299_V	0.511	0.52
21_K	301_K	0.510	0.52
66_K	90_R	0.510	0.52
265_V	291_T	0.510	0.52
119_F	123_I	0.510	0.52
129_D	140_R	0.508	0.51
71_G	256_G	0.507	0.51
54_Q	215_V	0.507	0.51
523_F	526_E	0.507	0.51
209_G	368_G	0.506	0.51
185_V	333_N	0.506	0.51
341_G	376_K	0.506	0.51
92_I	95_E	0.506	0.51
344_P	383_M	0.506	0.51
510_I	514_R	0.505	0.51
265_V	268_L	0.505	0.51
46_M	398_E	0.505	0.51
437_A	461_D	0.504	0.51
487_I	492_T	0.504	0.51
235_W	304_L	0.504	0.51
348_E	351_K	0.503	0.51
206_K	368_G	0.502	0.50
83_V	281_M	0.502	0.50
132_A	169_Y	0.502	0.50
153_P	267_P	0.502	0.50
20_K	515_T	0.502	0.50
258_H	280_R	0.501	0.50
337_S	506_L	0.500	0.50
518_D	521_I	0.500	0.50
298_T	310_T	0.500	0.50

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2rghA	2	0.9658	100	0.377	Contact Map
3da1A	1	0.8847	100	0.395	Contact Map
2qcuA	2	0.8919	100	0.443	Contact Map
4x9mA	1	0.6649	100	0.746	Contact Map
3dmeA	2	0.6342	100	0.749	Contact Map
4h1bA	1	0.6559	100	0.753	Contact Map
3axbA	2	0.6721	100	0.764	Contact Map
1ryiA	4	0.6342	100	0.767	Contact Map
1y56B	1	0.6649	100	0.768	Contact Map
2gagB	1	0.7009	100	0.772	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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