GLPK - BACSU - GREMLIN Contacts

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GLPK - Glycerol kinase

UniProt:	P18157	Sequences: METYILSLDQGTTSSRAILFNKEGKIVHSAQKEFTQYFPHPGWVEHNANEIWGSVLAVIASVISESGISASQIAGIGITNQRETTVVWDKDTGSPVYNAIVWQSRQTSGICEELREKGYNDKFREKTGLLIDPYFSGTKVKWILDNVEGAREKAEKGELLFGTIDTWLIWKMSGGKAHVTDYSNASRTLMFNIYDLKWDDELLDILGVPKSMLPEVKPSSHVYAETVDYHFFGKNIPIAGAAGDQQSALFGQACFEEGMGKNTYGTGCFMLMNTGEKAIKSEHGLLTTIAWGIDGKVNYALEGSIFVAGSAIQWLRDGLRMFQDSSLSESYAEKVDSTDGVYVVPAFVGLGTPYWDSDVRGSVFGLTRGTTKEHFIRATLESLAYQTKDVLDAMEADSNISLKTLRVDGGAVKNNFLMQFQGDLLNVPVERPEINETTALGAAYLAGIAVGFWKDRSEIANQWNLDKRFEPELEEEKRNELYKGWQKAVKAAMAFK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	496 (472)
Sequences:	12528 (8563)
Seq/√Len:	394.1

ECOLI - GLPK LYXK XYLB ARAB LSRK RHAB FUCK YGCE
BACSU - GLPK GNTK XYLB ARAB YOAC RHAB
HALSA - GLPK
SULSO - GLPK1 GLPK2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
200_D	210_K	4.186	1.00
110_I	145_D	3.823	1.00
21_N	25_K	3.510	1.00
17_A	58_V	3.341	1.00
113_E	145_D	3.308	1.00
388_K	482_Y	2.918	1.00
388_K	392_D	2.868	1.00
192_N	195_D	2.856	1.00
428_P	470_E	2.854	1.00
395_E	427_V	2.837	1.00
126_K	199_D	2.800	1.00
32_K	57_A	2.760	1.00
96_V	150_A	2.747	1.00
419_Q	423_D	2.725	1.00
37_Y	98_N	2.701	1.00
363_V	375_F	2.644	1.00
455_D	458_E	2.621	1.00
454_K	458_E	2.612	1.00
404_T	430_E	2.602	1.00
30_A	61_S	2.584	1.00
32_K	61_S	2.561	1.00
191_F	216_V	2.544	1.00
218_P	221_H	2.539	1.00
415_N	467_K	2.536	1.00
19_L	62_V	2.505	1.00
97_Y	147_V	2.491	1.00
49_N	171_K	2.482	1.00
52_W	171_K	2.442	1.00
90_K	155_E	2.437	1.00
89_D	153_K	2.434	1.00
388_K	479_N	2.361	1.00
192_N	199_D	2.339	1.00
56_L	229_Y	2.337	1.00
197_K	210_K	2.315	1.00
203_L	210_K	2.308	1.00
8_L	55_V	2.153	1.00
200_D	204_D	2.152	1.00
242_A	247_S	2.133	1.00
169_I	241_A	2.131	1.00
175_G	215_E	2.120	1.00
18_I	439_A	2.113	1.00
339_D	374_H	2.106	1.00
14_S	31_Q	2.004	1.00
311_A	379_T	1.999	1.00
472_E	475_E	1.992	1.00
49_N	94_S	1.976	1.00
122_K	125_E	1.957	1.00
113_E	117_K	1.945	1.00
371_T	374_H	1.917	1.00
40_H	43_W	1.913	1.00
35_T	50_E	1.907	1.00
61_S	65_E	1.904	1.00
268_C	308_A	1.900	1.00
395_E	401_S	1.877	1.00
5_I	447_G	1.857	1.00
156_K	178_H	1.855	1.00
173_S	238_I	1.850	1.00
342_Y	484_G	1.847	1.00
426_N	476_E	1.846	1.00
6_L	59_I	1.839	1.00
482_Y	486_Q	1.837	1.00
407_V	418_M	1.828	1.00
433_E	464_N	1.820	1.00
4_Y	27_V	1.816	1.00
126_K	201_E	1.813	1.00
10_Q	15_S	1.805	1.00
343_V	363_V	1.799	1.00
6_L	17_A	1.796	1.00
141_K	145_D	1.789	1.00
315_L	379_T	1.748	1.00
430_E	468_R	1.739	1.00
122_K	201_E	1.724	1.00
122_K	126_K	1.719	1.00
239_A	449_A	1.702	1.00
87_V	143_I	1.676	1.00
112_E	116_E	1.668	1.00
423_D	475_E	1.664	1.00
179_V	217_K	1.663	1.00
217_K	221_H	1.653	1.00
93_G	170_W	1.652	1.00
4_Y	19_L	1.651	1.00
89_D	94_S	1.649	1.00
329_E	333_E	1.644	1.00
428_P	468_R	1.628	1.00
259_M	404_T	1.625	1.00
334_K	374_H	1.609	1.00
423_D	472_E	1.601	1.00
257_E	275_G	1.599	1.00
222_V	239_A	1.592	1.00
385_Y	481_L	1.591	1.00
360_R	367_T	1.581	1.00
476_E	479_N	1.564	1.00
109_G	113_E	1.549	1.00
86_V	164_I	1.546	1.00
313_Q	317_D	1.540	1.00
87_V	212_M	1.539	1.00
115_R	120_N	1.526	1.00
5_I	452_F	1.520	1.00
149_G	152_E	1.509	1.00
392_D	486_Q	1.503	1.00
392_D	395_E	1.471	1.00
121_D	125_E	1.471	1.00
37_Y	50_E	1.464	1.00
28_H	62_V	1.461	1.00
47_N	50_E	1.442	1.00
30_A	62_V	1.442	1.00
474_E	477_K	1.437	1.00
63_I	70_A	1.429	1.00
30_A	58_V	1.423	1.00
169_I	223_Y	1.423	1.00
324_D	327_L	1.416	1.00
52_W	56_L	1.407	1.00
142_W	146_N	1.405	1.00
233_G	236_I	1.404	1.00
433_E	466_D	1.397	1.00
415_N	431_R	1.378	1.00
416_F	420_F	1.378	1.00
28_H	65_E	1.362	1.00
49_N	53_G	1.362	1.00
8_L	59_I	1.360	1.00
327_L	331_Y	1.359	1.00
377_R	381_E	1.359	1.00
415_N	469_F	1.348	1.00
209_P	212_M	1.334	1.00
194_Y	278_A	1.330	1.00
167_W	171_K	1.325	1.00
447_G	453_W	1.322	1.00
108_S	112_E	1.316	1.00
88_W	162_G	1.315	1.00
260_G	402_L	1.315	1.00
75_G	446_A	1.313	1.00
475_E	478_R	1.302	1.00
384_A	420_F	1.297	1.00
404_T	428_P	1.297	1.00
343_V	347_F	1.296	1.00
91_D	94_S	1.293	1.00
264_Y	421_Q	1.292	1.00
426_N	478_R	1.284	1.00
69_S	72_Q	1.284	1.00
327_L	330_S	1.280	1.00
182_Y	196_L	1.277	1.00
323_Q	326_S	1.272	1.00
217_K	223_Y	1.262	1.00
169_I	179_V	1.260	1.00
477_K	480_E	1.260	1.00
384_A	424_L	1.256	1.00
343_V	379_T	1.252	1.00
334_K	373_E	1.251	1.00
330_S	333_E	1.250	1.00
82_R	243_G	1.246	1.00
175_G	179_V	1.239	1.00
431_R	469_F	1.236	1.00
262_N	421_Q	1.235	1.00
22_K	452_F	1.234	1.00
122_K	205_I	1.234	1.00
53_G	57_A	1.233	1.00
323_Q	327_L	1.231	1.00
15_S	55_V	1.230	1.00
110_I	141_K	1.227	1.00
203_L	213_L	1.221	1.00
384_A	421_Q	1.221	1.00
418_M	469_F	1.219	1.00
305_I	386_Q	1.216	1.00
144_L	151_R	1.205	1.00
137_G	206_L	1.198	1.00
420_F	424_L	1.191	1.00
84_T	99_A	1.189	1.00
173_S	224_A	1.188	1.00
119_Y	205_I	1.183	1.00
426_N	479_N	1.181	1.00
242_A	445_L	1.180	1.00
15_S	54_S	1.179	1.00
222_V	237_P	1.168	1.00
201_E	204_D	1.168	1.00
329_E	332_A	1.152	1.00
123_F	131_I	1.151	1.00
8_L	17_A	1.150	1.00
319_L	375_F	1.150	1.00
57_A	61_S	1.146	1.00
147_V	150_A	1.143	1.00
117_K	205_I	1.142	1.00
19_L	68_I	1.140	1.00
258_G	403_K	1.139	1.00
388_K	425_L	1.139	1.00
47_N	98_N	1.138	1.00
364_F	488_A	1.137	1.00
307_V	311_A	1.126	1.00
87_V	154_A	1.121	1.00
256_E	259_M	1.116	1.00
4_Y	72_Q	1.113	1.00
392_D	482_Y	1.113	1.00
389_D	486_Q	1.109	1.00
182_Y	191_F	1.108	1.00
45_E	98_N	1.105	1.00
20_F	26_I	1.105	1.00
366_L	370_T	1.105	1.00
55_V	168_L	1.103	1.00
256_E	460_A	1.101	1.00
341_V	370_T	1.098	1.00
259_M	406_R	1.095	1.00
465_L	468_R	1.095	1.00
109_G	112_E	1.093	1.00
93_G	178_H	1.088	1.00
87_V	140_V	1.084	1.00
307_V	310_S	1.083	1.00
48_A	86_V	1.083	1.00
479_N	483_K	1.082	1.00
68_I	72_Q	1.080	1.00
111_C	131_I	1.077	1.00
222_V	449_A	1.077	1.00
361_G	366_L	1.072	1.00
182_Y	216_V	1.071	1.00
413_K	435_N	1.070	1.00
20_F	443_A	1.064	1.00
484_G	487_K	1.062	1.00
330_S	334_K	1.062	1.00
472_E	476_E	1.057	1.00
5_I	450_V	1.050	1.00
36_Q	46_H	1.049	1.00
119_Y	122_K	1.047	1.00
444_Y	459_I	1.046	1.00
350_L	353_P	1.045	1.00
149_G	153_K	1.043	1.00
162_G	178_H	1.041	1.00
110_I	113_E	1.040	1.00
112_E	115_R	1.038	1.00
60_A	229_Y	1.036	1.00
61_S	64_S	1.035	1.00
75_G	450_V	1.030	1.00
391_L	425_L	1.026	1.00
154_A	212_M	1.025	1.00
331_Y	416_F	1.023	1.00
78_I	169_I	1.023	1.00
406_R	430_E	1.020	1.00
179_V	223_Y	1.019	1.00
311_A	343_V	1.017	1.00
110_I	146_N	1.010	1.00
151_R	154_A	1.009	1.00
97_Y	150_A	1.008	1.00
256_E	457_S	1.008	1.00
51_I	164_I	1.006	1.00
106_Q	142_W	1.005	1.00
203_L	208_V	1.003	1.00
76_I	236_I	1.002	1.00
55_V	59_I	1.000	1.00
50_E	53_G	0.995	1.00
385_Y	424_L	0.985	1.00
260_G	272_M	0.985	1.00
60_A	64_S	0.984	1.00
4_Y	68_I	0.982	1.00
256_E	461_N	0.980	1.00
370_T	374_H	0.979	1.00
30_A	65_E	0.975	1.00
191_F	195_D	0.975	1.00
383_L	411_A	0.974	1.00
125_E	280_K	0.973	1.00
448_I	459_I	0.972	1.00
113_E	116_E	0.967	1.00
453_W	459_I	0.966	1.00
458_E	461_N	0.965	1.00
261_K	408_D	0.965	1.00
343_V	378_A	0.963	1.00
473_L	478_R	0.963	1.00
180_T	185_A	0.962	1.00
320_R	372_K	0.961	1.00
75_G	239_A	0.960	1.00
331_Y	334_K	0.950	1.00
447_G	452_F	0.948	1.00
377_R	416_F	0.947	1.00
137_G	189_L	0.947	1.00
56_L	60_A	0.947	1.00
34_F	54_S	0.946	1.00
444_Y	463_W	0.945	1.00
320_R	323_Q	0.945	1.00
388_K	424_L	0.941	1.00
140_V	161_F	0.941	1.00
239_A	450_V	0.939	1.00
87_V	161_F	0.939	1.00
17_A	62_V	0.937	1.00
5_I	75_G	0.937	1.00
322_F	326_S	0.932	1.00
123_F	189_L	0.932	1.00
256_E	403_K	0.926	1.00
356_D	359_V	0.925	1.00
331_Y	376_I	0.925	1.00
182_Y	292_G	0.924	1.00
6_L	19_L	0.921	1.00
20_F	440_L	0.921	1.00
44_V	103_Q	0.921	1.00
225_E	229_Y	0.917	1.00
74_A	450_V	0.917	1.00
411_A	417_L	0.917	1.00
473_L	476_E	0.916	1.00
196_L	218_P	0.916	1.00
270_M	391_L	0.915	1.00
79_T	438_T	0.914	1.00
404_T	468_R	0.913	1.00
150_A	153_K	0.913	1.00
21_N	27_V	0.909	1.00
63_I	73_I	0.908	1.00
328_S	376_I	0.906	1.00
155_E	211_S	0.897	1.00
148_E	152_E	0.895	1.00
32_K	58_V	0.894	1.00
94_S	171_K	0.893	1.00
328_S	414_N	0.892	1.00
125_E	194_Y	0.890	1.00
19_L	73_I	0.888	1.00
325_S	328_S	0.883	1.00
226_T	230_H	0.883	1.00
78_I	168_L	0.881	1.00
330_S	372_K	0.881	1.00
337_S	340_G	0.878	1.00
182_Y	218_P	0.877	1.00
405_L	425_L	0.876	1.00
227_V	230_H	0.875	1.00
71_S	233_G	0.872	1.00
329_E	415_N	0.870	1.00
143_I	150_A	0.870	1.00
268_C	387_T	0.869	1.00
366_L	375_F	0.868	1.00
77_G	239_A	0.867	1.00
97_Y	143_I	0.864	1.00
170_W	178_H	0.863	1.00
392_D	396_A	0.861	1.00
141_K	144_L	0.860	1.00
385_Y	482_Y	0.860	1.00
425_L	428_P	0.853	1.00
473_L	477_K	0.850	1.00
96_V	153_K	0.850	1.00
335_V	338_T	0.849	1.00
154_A	161_F	0.847	1.00
6_L	73_I	0.845	1.00
85_T	161_F	0.844	1.00
10_Q	168_L	0.844	1.00
166_T	180_T	0.842	1.00
226_T	231_F	0.837	1.00
113_E	141_K	0.837	1.00
289_I	292_G	0.836	1.00
412_V	435_N	0.832	1.00
248_A	408_D	0.826	1.00
217_K	240_G	0.825	1.00
204_D	210_K	0.819	1.00
33_E	313_Q	0.819	1.00
88_W	93_G	0.817	1.00
448_I	455_D	0.813	1.00
227_V	234_K	0.812	1.00
191_F	196_L	0.811	1.00
78_I	172_M	0.810	1.00
331_Y	373_E	0.809	1.00
199_D	202_L	0.808	1.00
359_V	362_S	0.807	1.00
228_D	231_F	0.803	1.00
83_E	187_R	0.800	1.00
197_K	200_D	0.800	1.00
111_C	133_P	0.800	1.00
197_K	215_E	0.799	1.00
39_P	43_W	0.799	1.00
105_R	132_D	0.799	1.00
314_W	317_D	0.798	1.00
90_K	153_K	0.797	1.00
326_S	330_S	0.796	1.00
201_E	205_I	0.795	1.00
115_R	131_I	0.795	1.00
163_T	188_T	0.793	1.00
347_F	350_L	0.793	1.00
430_E	465_L	0.791	1.00
448_I	456_R	0.791	1.00
332_A	416_F	0.789	1.00
380_L	420_F	0.786	1.00
330_S	373_E	0.785	1.00
50_E	54_S	0.785	1.00
340_G	481_L	0.784	1.00
111_C	138_T	0.784	1.00
342_Y	364_F	0.783	1.00
74_A	452_F	0.783	1.00
73_I	236_I	0.782	1.00
88_W	178_H	0.782	1.00
272_M	394_M	0.780	1.00
477_K	481_L	0.778	1.00
29_S	436_E	0.778	1.00
363_V	379_T	0.778	1.00
59_I	63_I	0.774	1.00
278_A	287_T	0.773	1.00
407_V	431_R	0.773	1.00
391_L	395_E	0.772	1.00
109_G	146_N	0.770	1.00
458_E	462_Q	0.768	1.00
419_Q	472_E	0.763	1.00
20_F	434_I	0.761	1.00
70_A	73_I	0.759	1.00
480_E	484_G	0.758	1.00
32_K	54_S	0.755	1.00
262_N	387_T	0.755	1.00
331_Y	335_V	0.755	1.00
245_Q	269_F	0.753	1.00
335_V	339_D	0.753	1.00
333_E	373_E	0.752	1.00
359_V	363_V	0.750	1.00
328_S	331_Y	0.748	1.00
252_Q	408_D	0.747	1.00
34_F	46_H	0.746	1.00
475_E	479_N	0.745	1.00
179_V	215_E	0.745	1.00
33_E	316_R	0.744	1.00
380_L	414_N	0.744	1.00
198_W	213_L	0.742	1.00
48_A	98_N	0.742	1.00
453_W	462_Q	0.741	1.00
315_L	375_F	0.740	1.00
165_D	241_A	0.740	1.00
315_L	376_I	0.738	1.00
26_I	29_S	0.737	1.00
480_E	483_K	0.737	1.00
260_G	405_L	0.735	1.00
288_T	292_G	0.735	1.00
87_V	96_V	0.733	1.00
412_V	418_M	0.731	1.00
481_L	484_G	0.731	1.00
393_A	396_A	0.731	1.00
63_I	68_I	0.731	1.00
326_S	329_E	0.731	1.00
226_T	229_Y	0.731	1.00
275_G	298_N	0.730	1.00
322_F	328_S	0.729	1.00
269_F	304_S	0.727	1.00
384_A	417_L	0.727	1.00
424_L	478_R	0.726	1.00
141_K	207_G	0.726	1.00
53_G	56_L	0.725	1.00
194_Y	280_K	0.723	1.00
385_Y	478_R	0.723	1.00
338_T	342_Y	0.720	1.00
45_E	106_Q	0.719	1.00
262_N	268_C	0.719	1.00
89_D	155_E	0.717	1.00
49_N	167_W	0.716	1.00
192_N	197_K	0.716	1.00
140_V	190_M	0.714	1.00
12_T	101_V	0.712	1.00
137_G	190_M	0.712	1.00
82_R	184_N	0.709	1.00
93_G	155_E	0.709	1.00
407_V	421_Q	0.709	1.00
126_K	192_N	0.708	1.00
7_S	77_G	0.707	1.00
82_R	302_E	0.706	1.00
180_T	216_V	0.705	1.00
388_K	486_Q	0.705	1.00
254_C	261_K	0.703	1.00
10_Q	55_V	0.703	1.00
252_Q	261_K	0.703	1.00
339_D	370_T	0.700	1.00
354_Y	359_V	0.700	1.00
320_R	324_D	0.698	1.00
346_A	350_L	0.697	1.00
56_L	230_H	0.696	1.00
52_W	226_T	0.695	1.00
56_L	171_K	0.694	1.00
328_S	416_F	0.694	1.00
109_G	145_D	0.693	1.00
225_E	235_N	0.693	1.00
169_I	173_S	0.693	1.00
102_W	267_G	0.693	1.00
180_T	214_P	0.691	1.00
225_E	228_D	0.689	0.99
457_S	460_A	0.687	0.99
356_D	363_V	0.687	0.99
123_F	202_L	0.687	0.99
15_S	34_F	0.686	0.99
112_E	358_D	0.685	0.99
308_A	383_L	0.683	0.99
389_D	482_Y	0.683	0.99
75_G	237_P	0.682	0.99
428_P	471_P	0.682	0.99
59_I	62_V	0.682	0.99
89_D	96_V	0.682	0.99
336_D	377_R	0.680	0.99
403_K	427_V	0.679	0.99
334_K	338_T	0.677	0.99
183_S	291_W	0.676	0.99
254_C	259_M	0.676	0.99
152_E	156_K	0.676	0.99
248_A	438_T	0.675	0.99
407_V	429_V	0.675	0.99
356_D	360_R	0.671	0.99
55_V	58_V	0.671	0.99
49_N	98_N	0.669	0.99
447_G	451_G	0.668	0.99
465_L	471_P	0.667	0.99
232_F	235_N	0.667	0.99
5_I	74_A	0.666	0.99
23_E	462_Q	0.664	0.99
127_T	202_L	0.663	0.99
57_A	60_A	0.663	0.99
167_W	170_W	0.662	0.99
188_T	198_W	0.661	0.99
86_V	99_A	0.661	0.99
141_K	151_R	0.659	0.99
88_W	156_K	0.658	0.99
219_S	241_A	0.656	0.99
183_S	186_S	0.655	0.99
459_I	463_W	0.654	0.99
244_D	266_T	0.653	0.99
166_T	178_H	0.652	0.99
349_G	353_P	0.651	0.99
340_G	377_R	0.649	0.99
420_F	478_R	0.649	0.99
455_D	461_N	0.649	0.99
121_D	124_R	0.647	0.99
10_Q	54_S	0.647	0.99
56_L	226_T	0.646	0.99
470_E	473_L	0.644	0.99
88_W	167_W	0.643	0.99
222_V	450_V	0.642	0.99
53_G	229_Y	0.641	0.99
335_V	374_H	0.641	0.99
18_I	26_I	0.641	0.99
479_N	482_Y	0.638	0.99
262_N	405_L	0.636	0.99
338_T	374_H	0.635	0.99
22_K	74_A	0.635	0.99
274_T	279_I	0.635	0.99
405_L	427_V	0.634	0.99
196_L	292_G	0.634	0.99
234_K	237_P	0.633	0.99
324_D	331_Y	0.633	0.99
405_L	429_V	0.631	0.99
183_S	242_A	0.631	0.99
459_I	462_Q	0.630	0.99
49_N	95_P	0.629	0.99
344_V	362_S	0.629	0.99
185_A	188_T	0.627	0.99
88_W	170_W	0.625	0.99
273_N	298_N	0.625	0.99
340_G	381_E	0.625	0.99
315_L	319_L	0.621	0.99
49_N	52_W	0.621	0.99
327_L	376_I	0.619	0.99
227_V	231_F	0.617	0.99
288_T	291_W	0.617	0.99
215_E	221_H	0.616	0.99
20_F	439_A	0.616	0.99
444_Y	462_Q	0.616	0.99
303_G	390_V	0.614	0.99
334_K	339_D	0.613	0.99
431_R	466_D	0.612	0.99
85_T	136_S	0.611	0.99
100_I	106_Q	0.609	0.99
343_V	382_S	0.608	0.99
108_S	133_P	0.607	0.99
237_P	450_V	0.606	0.99
402_L	427_V	0.604	0.99
434_I	440_L	0.604	0.99
232_F	236_I	0.603	0.99
80_N	184_N	0.603	0.99
291_W	294_D	0.603	0.99
59_I	230_H	0.602	0.99
444_Y	448_I	0.602	0.99
404_T	427_V	0.602	0.99
218_P	292_G	0.601	0.99
460_A	463_W	0.600	0.99
340_G	374_H	0.599	0.99
48_A	99_A	0.599	0.99
268_C	421_Q	0.598	0.99
381_E	420_F	0.597	0.99
202_L	205_I	0.596	0.99
354_Y	389_D	0.596	0.99
483_K	486_Q	0.596	0.99
358_D	361_G	0.594	0.99
56_L	59_I	0.594	0.99
419_Q	469_F	0.594	0.99
418_M	431_R	0.593	0.98
140_V	212_M	0.593	0.98
107_T	138_T	0.593	0.98
190_M	213_L	0.593	0.98
202_L	206_L	0.592	0.98
457_S	461_N	0.591	0.98
86_V	95_P	0.591	0.98
456_R	460_A	0.588	0.98
360_R	363_V	0.587	0.98
415_N	419_Q	0.587	0.98
185_A	198_W	0.585	0.98
114_L	206_L	0.585	0.98
84_T	101_V	0.584	0.98
433_E	465_L	0.583	0.98
271_L	300_A	0.583	0.98
305_I	390_V	0.582	0.98
227_V	232_F	0.582	0.98
338_T	381_E	0.580	0.98
181_D	186_S	0.580	0.98
131_I	189_L	0.579	0.98
204_D	209_P	0.579	0.98
230_H	235_N	0.577	0.98
227_V	235_N	0.577	0.98
243_G	246_Q	0.577	0.98
76_I	238_I	0.576	0.98
253_A	460_A	0.576	0.98
348_V	368_R	0.575	0.98
223_Y	240_G	0.575	0.98
414_N	417_L	0.575	0.98
341_V	378_A	0.574	0.98
396_A	486_Q	0.574	0.98
26_I	434_I	0.574	0.98
106_Q	146_N	0.574	0.98
312_I	328_S	0.574	0.98
81_Q	102_W	0.574	0.98
347_F	353_P	0.572	0.98
313_Q	316_R	0.572	0.98
292_G	295_G	0.572	0.98
80_N	164_I	0.571	0.98
151_R	207_G	0.569	0.98
245_Q	263_T	0.569	0.98
478_R	481_L	0.567	0.98
419_Q	422_G	0.567	0.98
226_T	235_N	0.565	0.98
337_S	377_R	0.565	0.98
328_S	334_K	0.565	0.98
337_S	374_H	0.564	0.98
153_K	156_K	0.563	0.98
38_F	44_V	0.563	0.98
327_L	335_V	0.560	0.98
100_I	143_I	0.560	0.98
281_S	284_G	0.560	0.98
129_L	135_F	0.560	0.98
29_S	65_E	0.559	0.98
5_I	453_W	0.559	0.98
448_I	453_W	0.559	0.98
219_S	242_A	0.556	0.98
377_R	420_F	0.556	0.98
175_G	217_K	0.556	0.98
264_Y	407_V	0.555	0.98
181_D	184_N	0.555	0.98
259_M	460_A	0.554	0.98
298_N	456_R	0.554	0.98
331_Y	336_D	0.554	0.98
338_T	377_R	0.553	0.98
184_N	187_R	0.553	0.98
204_D	207_G	0.553	0.98
353_P	356_D	0.553	0.98
114_L	138_T	0.552	0.98
464_N	471_P	0.551	0.98
47_N	53_G	0.548	0.97
426_N	473_L	0.548	0.97
208_V	213_L	0.547	0.97
339_D	369_G	0.547	0.97
45_E	97_Y	0.546	0.97
344_V	350_L	0.545	0.97
354_Y	486_Q	0.545	0.97
95_P	98_N	0.544	0.97
327_L	334_K	0.544	0.97
251_G	437_T	0.543	0.97
133_P	357_S	0.541	0.97
141_K	206_L	0.541	0.97
138_T	189_L	0.541	0.97
93_G	156_K	0.541	0.97
259_M	403_K	0.540	0.97
186_S	191_F	0.540	0.97
144_L	207_G	0.540	0.97
183_S	219_S	0.539	0.97
412_V	431_R	0.539	0.97
220_S	449_A	0.538	0.97
82_R	187_R	0.538	0.97
25_K	433_E	0.538	0.97
381_E	385_Y	0.537	0.97
262_N	270_M	0.537	0.97
135_F	187_R	0.537	0.97
230_H	236_I	0.536	0.97
4_Y	71_S	0.535	0.97
162_G	170_W	0.534	0.97
347_F	363_V	0.532	0.97
342_Y	385_Y	0.532	0.97
151_R	155_E	0.532	0.97
249_L	271_L	0.532	0.97
218_P	295_G	0.531	0.97
39_P	98_N	0.531	0.97
194_Y	197_K	0.531	0.97
151_R	209_P	0.531	0.97
327_L	332_A	0.528	0.97
464_N	469_F	0.528	0.97
421_Q	425_L	0.528	0.97
73_I	232_F	0.527	0.97
357_S	361_G	0.526	0.97
270_M	390_V	0.526	0.97
250_F	444_Y	0.525	0.97
79_T	442_A	0.524	0.97
274_T	301_L	0.523	0.97
440_L	444_Y	0.519	0.97
318_G	371_T	0.519	0.97
59_I	226_T	0.516	0.96
63_I	69_S	0.514	0.96
220_S	294_D	0.513	0.96
268_C	305_I	0.513	0.96
43_W	106_Q	0.512	0.96
422_G	429_V	0.511	0.96
479_N	486_Q	0.510	0.96
448_I	451_G	0.510	0.96
383_L	417_L	0.509	0.96
439_A	442_A	0.507	0.96
181_D	187_R	0.506	0.96
253_A	463_W	0.505	0.96
249_L	290_A	0.504	0.96
123_F	206_L	0.503	0.96
328_S	332_A	0.502	0.96
220_S	448_I	0.502	0.96
13_T	16_R	0.502	0.96
226_T	232_F	0.500	0.96
426_N	475_E	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ezwA	3	0.996	100	0.131	Contact Map
3g25A	3	0.998	100	0.132	Contact Map
3ll3A	2	0.9677	100	0.136	Contact Map
3h3nX	3	0.996	100	0.136	Contact Map
2d4wA	2	0.9899	100	0.141	Contact Map
2zf5O	3	0.9819	100	0.143	Contact Map
3wxlA	2	0.9879	100	0.144	Contact Map
2dpnA	2	0.9859	100	0.147	Contact Map
2itmA	2	0.9456	100	0.149	Contact Map
3hz6A	1	0.9617	100	0.152	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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