RECN - BACSU - GREMLIN Contacts

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RECN - DNA repair protein RecN

UniProt:	P17894	Sequences: MLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISLLVGGRGSSEFVRYGEAKAELEGLFLLESGHPVLGVCAEQGIDVSDEMIVMRRDISTSGKSVCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLQLLDKFAGAEVESALKTYQEGYQRYVKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELNEDEQLQEERQQISNFEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLKKMSESVSNSYYLLEDATFQMRNMLDELEFDPERLNYIETRLNEIKQLKRKYGATVEDILEYASKIEEEIDQIENRDSHLQSLKKELDSVGKDVAVEAANVSQIRKTWAKKLADEIHRELKSLYMEKSTFDTEFKVRTASRNEEAPLVNGQPVQLTEQGIDLVKFLISTNTGEPLKSLSKVASGGELSRVMLAIKSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLPQVAAMADTHLYIAKELKDGRTTTRVKPLSKQEKVAEIGRMIAGVEVTDLTKRHAKELLKQADQVKTTG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	576 (531)
Sequences:	5188 (4305)
Seq/√Len:	186.8

ECOLI - RECN SBCC
BACSU - RECN SMC
HALSA - Q9HS95 SPH1 RAD50
SULSO - RAD50

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
216_E	298_R	5.853	1.00
537_S	540_E	3.955	1.00
189_R	333_E	3.735	1.00
180_S	348_K	3.545	1.00
534_K	540_E	3.325	1.00
480_V	488_I	3.282	1.00
201_E	331_E	3.183	1.00
8_K	15_E	3.061	1.00
327_A	331_E	2.849	1.00
201_E	327_A	2.805	1.00
366_S	370_K	2.786	1.00
319_T	322_D	2.718	1.00
355_G	359_A	2.709	1.00
273_N	277_L	2.579	1.00
172_L	354_V	2.531	1.00
481_S	548_M	2.518	1.00
4_E	17_T	2.512	1.00
346_S	350_E	2.381	1.00
197_L	327_A	2.368	1.00
298_R	301_Y	2.362	1.00
394_F	429_F	2.356	1.00
198_E	202_S	2.350	1.00
190_L	194_Q	2.327	1.00
172_L	351_L	2.300	1.00
4_E	19_S	2.289	1.00
26_V	514_A	2.277	1.00
168_R	350_E	2.235	1.00
80_C	85_I	2.229	1.00
207_L	321_E	2.224	1.00
243_G	246_W	2.221	1.00
375_K	379_E	2.211	1.00
194_Q	338_E	2.210	1.00
203_A	308_E	2.182	1.00
366_S	424_I	2.166	1.00
45_L	66_G	2.148	1.00
173_L	177_K	2.113	1.00
521_A	534_K	2.093	1.00
352_D	355_G	2.074	1.00
358_V	419_L	2.071	1.00
165_G	354_V	2.062	1.00
173_L	351_L	2.046	1.00
194_Q	198_E	2.032	1.00
206_E	212_Q	2.016	1.00
74_H	80_C	2.012	1.00
177_K	181_E	1.989	1.00
209_E	305_R	1.972	1.00
212_Q	216_E	1.962	1.00
243_G	250_A	1.954	1.00
343_H	346_S	1.942	1.00
175_K	343_H	1.925	1.00
159_L	163_Q	1.909	1.00
6_S	17_T	1.896	1.00
397_E	430_L	1.889	1.00
6_S	15_E	1.877	1.00
318_A	322_D	1.866	1.00
398_F	425_D	1.865	1.00
171_K	175_K	1.846	1.00
523_E	532_R	1.843	1.00
350_E	353_S	1.833	1.00
190_L	334_I	1.829	1.00
361_E	364_N	1.823	1.00
349_K	353_S	1.809	1.00
65_E	68_F	1.804	1.00
158_A	368_I	1.797	1.00
176_L	351_L	1.797	1.00
151_A	372_W	1.794	1.00
519_Y	536_L	1.789	1.00
205_L	309_I	1.786	1.00
172_L	176_L	1.785	1.00
348_K	352_D	1.782	1.00
325_E	329_K	1.770	1.00
437_E	528_R	1.764	1.00
26_V	517_H	1.761	1.00
325_E	328_S	1.742	1.00
350_E	354_V	1.741	1.00
153_A	368_I	1.739	1.00
226_I	230_L	1.733	1.00
213_L	302_I	1.731	1.00
165_G	361_E	1.730	1.00
243_G	248_G	1.723	1.00
485_A	507_L	1.715	1.00
233_A	237_L	1.714	1.00
270_S	277_L	1.704	1.00
43_S	48_G	1.688	1.00
185_E	189_R	1.686	1.00
200_I	323_I	1.685	1.00
265_K	269_E	1.683	1.00
377_A	396_T	1.673	1.00
21_E	535_P	1.663	1.00
178_Q	182_S	1.659	1.00
108_V	121_I	1.655	1.00
243_G	247_V	1.646	1.00
317_G	323_I	1.642	1.00
269_E	273_N	1.637	1.00
352_D	356_K	1.635	1.00
357_D	361_E	1.630	1.00
77_L	80_C	1.624	1.00
170_V	173_L	1.601	1.00
329_K	333_E	1.598	1.00
399_K	426_L	1.592	1.00
328_S	332_E	1.590	1.00
297_E	300_N	1.589	1.00
172_L	175_K	1.587	1.00
318_A	323_I	1.581	1.00
544_E	547_R	1.573	1.00
208_N	211_E	1.571	1.00
332_E	336_Q	1.567	1.00
304_T	308_E	1.549	1.00
162_Y	365_V	1.541	1.00
169_Y	351_L	1.539	1.00
357_D	360_V	1.530	1.00
274_S	281_A	1.527	1.00
162_Y	358_V	1.527	1.00
217_R	302_I	1.526	1.00
356_K	360_V	1.524	1.00
224_E	228_E	1.523	1.00
18_V	533_V	1.507	1.00
181_E	185_E	1.503	1.00
489_A	513_M	1.501	1.00
210_D	313_K	1.481	1.00
448_G	475_E	1.469	1.00
142_N	145_Q	1.467	1.00
140_D	428_K	1.467	1.00
328_S	331_E	1.456	1.00
261_N	288_M	1.452	1.00
177_K	180_S	1.437	1.00
326_Y	329_K	1.432	1.00
433_T	445_V	1.427	1.00
10_F	41_A	1.426	1.00
161_T	361_E	1.425	1.00
519_Y	534_K	1.423	1.00
270_S	280_D	1.412	1.00
395_D	439_L	1.401	1.00
326_Y	330_I	1.393	1.00
131_Q	448_G	1.393	1.00
359_A	424_I	1.392	1.00
322_D	325_E	1.390	1.00
222_N	237_L	1.386	1.00
251_S	255_E	1.378	1.00
539_Q	543_A	1.376	1.00
371_T	375_K	1.376	1.00
377_A	395_D	1.372	1.00
359_A	363_A	1.372	1.00
74_H	77_L	1.367	1.00
32_G	450_E	1.360	1.00
158_A	161_T	1.357	1.00
176_L	348_K	1.353	1.00
3_A	91_M	1.345	1.00
363_A	367_Q	1.341	1.00
493_H	515_D	1.339	1.00
246_W	249_M	1.339	1.00
222_N	225_K	1.335	1.00
42_I	472_I	1.329	1.00
210_D	214_Q	1.328	1.00
448_G	479_G	1.318	1.00
176_L	344_L	1.316	1.00
108_V	113_V	1.310	1.00
74_H	78_G	1.307	1.00
189_R	193_I	1.299	1.00
144_L	422_Q	1.291	1.00
164_E	168_R	1.285	1.00
25_T	518_L	1.285	1.00
174_K	178_Q	1.283	1.00
223_F	227_Y	1.281	1.00
197_L	334_I	1.279	1.00
374_K	377_A	1.275	1.00
176_L	180_S	1.275	1.00
396_T	429_F	1.273	1.00
192_L	196_Q	1.272	1.00
24_L	503_C	1.270	1.00
360_V	364_N	1.269	1.00
228_E	232_N	1.269	1.00
516_T	535_P	1.266	1.00
255_E	272_S	1.264	1.00
62_A	68_F	1.264	1.00
497_I	515_D	1.260	1.00
324_L	327_A	1.254	1.00
144_L	427_V	1.253	1.00
435_T	524_L	1.248	1.00
398_F	427_V	1.247	1.00
345_Q	348_K	1.243	1.00
300_N	304_T	1.237	1.00
250_A	254_L	1.236	1.00
331_E	335_D	1.234	1.00
298_R	302_I	1.234	1.00
217_R	303_E	1.234	1.00
75_P	80_C	1.233	1.00
168_R	171_K	1.227	1.00
175_K	178_Q	1.227	1.00
216_E	302_I	1.223	1.00
191_D	195_F	1.222	1.00
339_N	342_S	1.219	1.00
217_R	221_S	1.217	1.00
464_S	498_G	1.215	1.00
208_N	212_Q	1.211	1.00
197_L	331_E	1.207	1.00
94_M	122_G	1.205	1.00
267_M	281_A	1.205	1.00
165_G	168_R	1.205	1.00
335_D	338_E	1.204	1.00
362_A	424_I	1.204	1.00
351_L	355_G	1.202	1.00
57_Y	438_P	1.200	1.00
246_W	250_A	1.199	1.00
11_A	37_I	1.198	1.00
62_A	65_E	1.192	1.00
160_K	164_E	1.189	1.00
262_E	265_K	1.183	1.00
161_T	165_G	1.177	1.00
172_L	350_E	1.176	1.00
173_L	355_G	1.172	1.00
271_V	281_A	1.170	1.00
95_R	107_R	1.169	1.00
332_E	335_D	1.158	1.00
214_Q	218_Q	1.157	1.00
358_V	362_A	1.155	1.00
205_L	320_V	1.155	1.00
524_L	529_T	1.151	1.00
14_E	530_T	1.150	1.00
219_Q	261_N	1.146	1.00
349_K	352_D	1.141	1.00
213_L	217_R	1.141	1.00
518_L	533_V	1.140	1.00
486_Q	490_E	1.138	1.00
366_S	425_D	1.133	1.00
76_V	79_V	1.129	1.00
335_D	339_N	1.129	1.00
233_A	236_A	1.126	1.00
222_N	226_I	1.125	1.00
379_E	382_R	1.122	1.00
9_N	59_E	1.121	1.00
193_I	197_L	1.120	1.00
175_K	336_Q	1.115	1.00
198_E	201_E	1.114	1.00
245_D	248_G	1.112	1.00
276_Y	280_D	1.111	1.00
208_N	321_E	1.108	1.00
158_A	364_N	1.107	1.00
185_E	188_H	1.107	1.00
232_N	253_Q	1.104	1.00
244_L	248_G	1.103	1.00
216_E	219_Q	1.097	1.00
266_K	269_E	1.097	1.00
106_C	113_V	1.085	1.00
168_R	354_V	1.081	1.00
475_E	504_I	1.079	1.00
307_N	310_K	1.077	1.00
251_S	254_L	1.076	1.00
191_D	194_Q	1.071	1.00
353_S	357_D	1.067	1.00
161_T	164_E	1.064	1.00
234_Y	238_R	1.063	1.00
525_K	530_T	1.061	1.00
165_G	357_D	1.059	1.00
348_K	351_L	1.059	1.00
156_E	160_K	1.057	1.00
229_S	233_A	1.056	1.00
252_A	255_E	1.055	1.00
341_D	345_Q	1.047	1.00
117_S	120_E	1.046	1.00
161_T	364_N	1.046	1.00
229_S	257_I	1.045	1.00
74_H	79_V	1.039	1.00
274_S	278_L	1.037	1.00
270_S	274_S	1.033	1.00
203_A	312_L	1.032	1.00
129_H	455_M	1.030	1.00
32_G	484_V	1.027	1.00
31_T	484_V	1.026	1.00
182_S	185_E	1.022	1.00
58_G	68_F	1.015	1.00
158_A	361_E	1.015	1.00
371_T	378_D	1.013	1.00
302_I	306_L	1.011	1.00
197_L	330_I	1.008	0.99
366_S	400_V	1.001	0.99
309_I	324_L	0.997	0.99
247_V	251_S	0.996	0.99
172_L	347_L	0.995	0.99
486_Q	513_M	0.994	0.99
12_I	39_I	0.993	0.99
452_S	479_G	0.993	0.99
184_Q	188_H	0.991	0.99
351_L	354_V	0.991	0.99
262_E	266_K	0.990	0.99
65_E	70_L	0.989	0.99
476_V	507_L	0.989	0.99
67_L	91_M	0.987	0.99
168_R	172_L	0.986	0.99
320_V	324_L	0.984	0.99
377_A	381_H	0.983	0.99
7_I	13_I	0.982	0.99
486_Q	552_V	0.981	0.99
223_F	292_L	0.979	0.99
518_L	535_P	0.974	0.99
360_V	363_A	0.969	0.99
370_K	398_F	0.966	0.99
524_L	527_G	0.963	0.99
453_R	480_V	0.958	0.99
216_E	220_I	0.957	0.99
139_E	142_N	0.950	0.99
163_Q	167_Q	0.949	0.99
397_E	428_K	0.948	0.99
388_Y	484_V	0.948	0.99
329_K	332_E	0.948	0.99
114_T	117_S	0.948	0.99
192_L	195_F	0.947	0.99
78_G	85_I	0.946	0.99
61_K	97_D	0.944	0.99
132_H	135_Q	0.944	0.99
370_K	374_K	0.942	0.99
333_E	336_Q	0.942	0.99
344_L	348_K	0.941	0.99
378_D	382_R	0.940	0.99
222_N	233_A	0.939	0.99
58_G	66_G	0.936	0.99
450_E	475_E	0.936	0.99
384_L	392_S	0.934	0.99
453_R	484_V	0.934	0.99
263_P	266_K	0.933	0.99
47_G	477_D	0.933	0.99
508_P	548_M	0.929	0.99
107_R	112_L	0.928	0.99
233_A	285_M	0.928	0.99
3_A	69_L	0.926	0.99
225_K	228_E	0.925	0.99
523_E	530_T	0.924	0.99
275_Y	279_E	0.919	0.99
158_A	162_Y	0.918	0.99
345_Q	349_K	0.918	0.99
313_K	323_I	0.917	0.99
381_H	385_K	0.916	0.99
367_Q	370_K	0.916	0.99
67_L	71_E	0.913	0.99
383_E	491_K	0.911	0.99
257_I	264_L	0.910	0.99
495_V	501_V	0.909	0.99
187_A	190_L	0.909	0.99
180_S	344_L	0.909	0.99
162_Y	362_A	0.907	0.99
211_E	215_E	0.906	0.99
94_M	121_I	0.905	0.99
437_E	440_K	0.902	0.99
295_D	301_Y	0.901	0.99
277_L	281_A	0.900	0.99
212_Q	215_E	0.900	0.99
508_P	550_A	0.898	0.99
46_V	126_L	0.898	0.99
480_V	484_V	0.893	0.99
165_G	169_Y	0.892	0.99
169_Y	355_G	0.888	0.99
58_G	62_A	0.887	0.99
539_Q	542_V	0.886	0.99
127_D	459_K	0.886	0.99
197_L	201_E	0.885	0.99
32_G	453_R	0.885	0.99
374_K	378_D	0.885	0.99
127_D	136_L	0.884	0.99
363_A	400_V	0.878	0.99
96_R	104_S	0.878	0.99
188_H	191_D	0.877	0.99
364_N	367_Q	0.876	0.99
320_V	323_I	0.874	0.99
270_S	281_A	0.872	0.99
354_V	357_D	0.871	0.99
220_I	294_F	0.870	0.99
140_D	426_L	0.870	0.99
312_L	316_Y	0.870	0.99
386_S	491_K	0.869	0.98
227_Y	230_L	0.869	0.98
247_V	278_L	0.868	0.98
10_F	44_L	0.868	0.98
227_Y	231_Q	0.868	0.98
77_L	81_A	0.865	0.98
250_A	271_V	0.864	0.98
133_D	136_L	0.859	0.98
171_K	174_K	0.858	0.98
169_Y	173_L	0.858	0.98
78_G	81_A	0.857	0.98
193_I	196_Q	0.854	0.98
307_N	311_Q	0.850	0.98
44_L	50_G	0.848	0.98
248_G	251_S	0.847	0.98
179_L	183_E	0.842	0.98
436_G	529_T	0.840	0.98
309_I	323_I	0.839	0.98
62_A	66_G	0.838	0.98
272_S	275_Y	0.834	0.98
242_G	245_D	0.832	0.98
75_P	79_V	0.832	0.98
494_K	497_I	0.831	0.98
313_K	320_V	0.830	0.98
44_L	76_V	0.827	0.98
276_Y	279_E	0.827	0.98
195_F	199_E	0.827	0.98
475_E	478_T	0.825	0.98
372_W	375_K	0.824	0.98
475_E	479_G	0.822	0.98
199_E	315_K	0.821	0.98
79_V	85_I	0.819	0.98
12_I	37_I	0.819	0.98
211_E	214_Q	0.815	0.98
393_T	432_S	0.814	0.98
7_I	38_I	0.813	0.98
364_N	371_T	0.811	0.98
13_I	16_L	0.810	0.98
157_S	161_T	0.809	0.98
310_K	313_K	0.808	0.98
189_R	192_L	0.808	0.98
193_I	330_I	0.807	0.98
485_A	509_Q	0.806	0.98
367_Q	371_T	0.806	0.98
484_V	488_I	0.805	0.98
210_D	310_K	0.805	0.98
175_K	350_E	0.803	0.97
129_H	132_H	0.800	0.97
193_I	333_E	0.799	0.97
230_L	233_A	0.798	0.97
229_S	253_Q	0.797	0.97
270_S	284_Q	0.797	0.97
230_L	234_Y	0.796	0.97
157_S	160_K	0.796	0.97
517_H	541_K	0.794	0.97
270_S	273_N	0.794	0.97
131_Q	479_G	0.793	0.97
479_G	506_H	0.791	0.97
69_L	72_S	0.789	0.97
450_E	453_R	0.789	0.97
145_Q	149_K	0.789	0.97
186_M	190_L	0.788	0.97
453_R	475_E	0.787	0.97
432_S	439_L	0.787	0.97
166_Y	170_V	0.786	0.97
2_L	78_G	0.786	0.97
312_L	315_K	0.781	0.97
168_R	357_D	0.780	0.97
400_V	424_I	0.779	0.97
164_E	167_Q	0.776	0.97
452_S	506_H	0.774	0.97
214_Q	217_R	0.770	0.97
435_T	438_P	0.768	0.97
540_E	543_A	0.766	0.97
346_S	349_K	0.764	0.97
253_Q	256_D	0.761	0.97
365_V	369_R	0.761	0.97
226_I	260_I	0.760	0.97
67_L	70_L	0.758	0.96
47_G	478_T	0.757	0.96
475_E	506_H	0.757	0.96
493_H	513_M	0.755	0.96
452_S	475_E	0.754	0.96
452_S	477_D	0.754	0.96
487_A	490_E	0.753	0.96
152_G	157_S	0.752	0.96
167_Q	171_K	0.750	0.96
10_F	40_D	0.749	0.96
524_L	528_R	0.748	0.96
60_A	100_T	0.748	0.96
264_L	288_M	0.748	0.96
126_L	130_G	0.748	0.96
363_A	424_I	0.747	0.96
10_F	54_F	0.746	0.96
538_K	542_V	0.746	0.96
347_L	351_L	0.745	0.96
224_E	227_Y	0.744	0.96
525_K	532_R	0.743	0.96
342_S	346_S	0.741	0.96
286_R	290_D	0.740	0.96
196_Q	199_E	0.739	0.96
339_N	343_H	0.739	0.96
322_D	326_Y	0.738	0.96
38_I	502_L	0.736	0.96
170_V	174_K	0.736	0.96
324_L	328_S	0.736	0.96
376_L	396_T	0.734	0.96
20_F	518_L	0.734	0.96
7_I	37_I	0.733	0.96
94_M	118_L	0.733	0.96
162_Y	165_G	0.731	0.96
448_G	452_S	0.731	0.96
383_E	386_S	0.730	0.96
36_S	40_D	0.730	0.96
342_S	345_Q	0.730	0.96
273_N	276_Y	0.727	0.96
145_Q	422_Q	0.726	0.95
5_L	20_F	0.726	0.95
180_S	184_Q	0.726	0.95
303_E	307_N	0.725	0.95
56_R	66_G	0.724	0.95
385_K	390_E	0.723	0.95
541_K	546_G	0.722	0.95
9_N	14_E	0.721	0.95
453_R	506_H	0.721	0.95
259_D	262_E	0.721	0.95
250_A	253_Q	0.719	0.95
247_V	250_A	0.715	0.95
295_D	298_R	0.714	0.95
173_L	176_L	0.714	0.95
21_E	516_T	0.713	0.95
165_G	172_L	0.712	0.95
75_P	78_G	0.712	0.95
391_K	435_T	0.712	0.95
304_T	307_N	0.712	0.95
230_L	288_M	0.712	0.95
450_E	480_V	0.710	0.95
428_K	443_S	0.710	0.95
236_A	240_E	0.710	0.95
50_G	98_I	0.709	0.95
250_A	255_E	0.709	0.95
225_K	229_S	0.709	0.95
65_E	71_E	0.708	0.95
144_L	398_F	0.708	0.95
452_S	459_K	0.703	0.95
353_S	356_K	0.702	0.95
434_N	437_E	0.702	0.95
431_I	445_V	0.701	0.95
135_Q	138_M	0.701	0.95
379_E	383_E	0.699	0.94
229_S	232_N	0.699	0.94
94_M	106_C	0.699	0.94
215_E	219_Q	0.698	0.94
477_D	507_L	0.698	0.94
284_Q	287_N	0.697	0.94
391_K	524_L	0.697	0.94
76_V	80_C	0.695	0.94
32_G	480_V	0.695	0.94
450_E	504_I	0.694	0.94
45_L	64_L	0.694	0.94
162_Y	166_Y	0.693	0.94
521_A	532_R	0.692	0.94
455_M	478_T	0.692	0.94
381_H	392_S	0.691	0.94
29_G	33_A	0.690	0.94
97_D	107_R	0.690	0.94
280_D	283_F	0.687	0.94
215_E	218_Q	0.686	0.94
266_K	284_Q	0.686	0.94
258_S	261_N	0.686	0.94
274_S	277_L	0.683	0.94
238_R	241_Q	0.682	0.94
381_H	393_T	0.682	0.94
382_R	386_S	0.681	0.94
210_D	320_V	0.680	0.94
476_V	510_V	0.680	0.94
481_S	544_E	0.679	0.94
206_E	209_E	0.679	0.94
483_R	486_Q	0.677	0.93
287_N	290_D	0.677	0.93
45_L	78_G	0.676	0.93
28_T	475_E	0.675	0.93
143_H	396_T	0.671	0.93
306_L	310_K	0.671	0.93
455_M	484_V	0.670	0.93
477_D	489_A	0.667	0.93
327_A	330_I	0.666	0.93
452_S	476_V	0.665	0.93
147_L	427_V	0.664	0.93
391_K	394_F	0.664	0.93
292_L	295_D	0.662	0.93
134_N	138_M	0.662	0.93
39_I	504_I	0.659	0.93
373_A	377_A	0.659	0.93
340_R	344_L	0.658	0.92
127_D	132_H	0.657	0.92
9_N	60_A	0.657	0.92
452_S	455_M	0.657	0.92
318_A	326_Y	0.656	0.92
282_T	286_R	0.655	0.92
269_E	272_S	0.653	0.92
505_T	511_A	0.651	0.92
483_R	487_A	0.650	0.92
543_A	553_E	0.650	0.92
223_F	226_I	0.649	0.92
362_A	419_L	0.649	0.92
127_D	130_G	0.648	0.92
18_V	38_I	0.646	0.92
293_E	296_P	0.646	0.92
129_H	137_L	0.645	0.92
504_I	520_I	0.645	0.92
226_I	288_M	0.645	0.92
116_A	119_R	0.644	0.92
363_A	366_S	0.644	0.92
175_K	179_L	0.643	0.92
4_E	67_L	0.643	0.92
122_G	125_L	0.643	0.92
4_E	79_V	0.643	0.92
296_P	299_L	0.642	0.92
190_L	338_E	0.640	0.91
452_S	489_A	0.639	0.91
47_G	448_G	0.635	0.91
225_K	233_A	0.633	0.91
186_M	337_I	0.632	0.91
11_A	36_S	0.632	0.91
12_I	16_L	0.632	0.91
459_K	478_T	0.630	0.91
455_M	507_L	0.630	0.91
232_N	236_A	0.629	0.91
135_Q	143_H	0.627	0.91
466_Q	499_S	0.627	0.91
514_A	517_H	0.626	0.91
490_E	513_M	0.626	0.91
339_N	346_S	0.625	0.90
162_Y	361_E	0.624	0.90
167_Q	421_E	0.623	0.90
450_E	484_V	0.623	0.90
65_E	112_L	0.620	0.90
235_N	239_S	0.619	0.90
393_T	439_L	0.619	0.90
33_A	475_E	0.618	0.90
210_D	306_L	0.615	0.90
343_H	347_L	0.614	0.90
448_G	504_I	0.613	0.90
222_N	241_Q	0.612	0.90
147_L	150_F	0.611	0.89
171_K	178_Q	0.610	0.89
234_Y	282_T	0.608	0.89
230_L	237_L	0.607	0.89
153_A	158_A	0.605	0.89
452_S	480_V	0.603	0.89
153_A	156_E	0.603	0.89
453_R	479_G	0.603	0.89
8_K	63_E	0.601	0.89
483_R	553_E	0.601	0.89
316_Y	323_I	0.601	0.89
122_G	126_L	0.600	0.89
419_L	424_I	0.599	0.89
242_G	248_G	0.599	0.89
40_D	502_L	0.598	0.88
32_G	506_H	0.597	0.88
205_L	209_E	0.597	0.88
122_G	130_G	0.596	0.88
484_V	487_A	0.596	0.88
11_A	484_V	0.596	0.88
68_F	71_E	0.595	0.88
174_K	177_K	0.593	0.88
460_S	495_V	0.592	0.88
187_A	191_D	0.589	0.88
151_A	368_I	0.588	0.88
32_G	459_K	0.588	0.88
67_L	93_V	0.588	0.88
222_N	227_Y	0.588	0.88
163_Q	421_E	0.588	0.88
493_H	496_S	0.588	0.88
127_D	131_Q	0.585	0.87
223_F	237_L	0.585	0.87
431_I	454_V	0.583	0.87
218_Q	221_S	0.583	0.87
153_A	159_L	0.583	0.87
375_K	526_D	0.582	0.87
258_S	265_K	0.582	0.87
194_Q	334_I	0.582	0.87
168_R	353_S	0.582	0.87
491_K	495_V	0.581	0.87
380_I	458_I	0.581	0.87
152_G	156_E	0.580	0.87
248_G	255_E	0.579	0.87
371_T	526_D	0.578	0.87
159_L	162_Y	0.578	0.87
455_M	459_K	0.576	0.87
27_L	520_I	0.576	0.87
37_I	40_D	0.574	0.86
6_S	77_L	0.574	0.86
265_K	268_S	0.573	0.86
32_G	449_G	0.573	0.86
32_G	455_M	0.572	0.86
263_P	291_E	0.572	0.86
37_I	477_D	0.572	0.86
459_K	506_H	0.571	0.86
150_F	379_E	0.571	0.86
535_P	538_K	0.570	0.86
223_F	230_L	0.570	0.86
423_G	427_V	0.568	0.86
420_T	423_G	0.567	0.86
131_Q	452_S	0.566	0.86
478_T	507_L	0.565	0.85
242_G	246_W	0.565	0.85
453_R	482_G	0.565	0.85
62_A	70_L	0.565	0.85
236_A	250_A	0.562	0.85
418_Q	422_Q	0.560	0.85
430_L	439_L	0.559	0.85
200_I	203_A	0.559	0.85
261_N	264_L	0.558	0.85
3_A	19_S	0.556	0.85
220_I	299_L	0.556	0.85
143_H	146_L	0.554	0.84
400_V	425_D	0.554	0.84
64_L	70_L	0.553	0.84
450_E	506_H	0.553	0.84
475_E	480_V	0.553	0.84
532_R	538_K	0.552	0.84
66_G	70_L	0.552	0.84
534_K	538_K	0.550	0.84
237_L	241_Q	0.550	0.84
382_R	385_K	0.548	0.84
381_H	384_L	0.548	0.84
160_K	163_Q	0.548	0.84
251_S	268_S	0.546	0.84
77_L	85_I	0.546	0.84
267_M	284_Q	0.544	0.83
70_L	77_L	0.544	0.83
526_D	539_Q	0.544	0.83
12_I	477_D	0.544	0.83
153_A	157_S	0.543	0.83
63_E	68_F	0.543	0.83
388_Y	492_I	0.543	0.83
234_Y	239_S	0.542	0.83
188_H	192_L	0.541	0.83
358_V	361_E	0.541	0.83
492_I	503_C	0.540	0.83
12_I	484_V	0.540	0.83
227_Y	240_E	0.540	0.83
47_G	450_E	0.539	0.83
134_N	137_L	0.539	0.83
452_S	485_A	0.539	0.83
434_N	442_L	0.537	0.82
179_L	354_V	0.537	0.82
300_N	303_E	0.536	0.82
534_K	543_A	0.536	0.82
123_R	139_E	0.536	0.82
371_T	374_K	0.535	0.82
361_E	368_I	0.535	0.82
58_G	61_K	0.534	0.82
466_Q	472_I	0.534	0.82
477_D	506_H	0.533	0.82
166_Y	169_Y	0.533	0.82
27_L	38_I	0.533	0.82
228_E	231_Q	0.530	0.82
49_R	115_I	0.530	0.82
530_T	534_K	0.529	0.82
490_E	493_H	0.528	0.81
183_E	187_A	0.528	0.81
209_E	212_Q	0.527	0.81
127_D	492_I	0.526	0.81
455_M	480_V	0.526	0.81
376_L	380_I	0.526	0.81
477_D	488_I	0.525	0.81
395_D	398_F	0.525	0.81
545_I	550_A	0.525	0.81
473_F	479_G	0.523	0.81
330_I	333_E	0.523	0.81
178_Q	181_E	0.522	0.81
113_V	117_S	0.522	0.81
231_Q	235_N	0.522	0.81
79_V	121_I	0.521	0.81
453_R	485_A	0.520	0.80
416_P	419_L	0.520	0.80
63_E	66_G	0.519	0.80
450_E	459_K	0.519	0.80
239_S	242_G	0.518	0.80
452_S	478_T	0.518	0.80
215_E	262_E	0.518	0.80
28_T	477_D	0.517	0.80
11_A	477_D	0.517	0.80
452_S	484_V	0.516	0.80
31_T	475_E	0.516	0.80
477_D	480_V	0.514	0.80
502_L	535_P	0.514	0.80
39_I	128_I	0.514	0.80
58_G	67_L	0.514	0.80
219_Q	226_I	0.513	0.80
347_L	350_E	0.513	0.80
422_Q	425_D	0.512	0.79
243_G	251_S	0.512	0.79
528_R	531_T	0.512	0.79
528_R	532_R	0.511	0.79
31_T	481_S	0.511	0.79
201_E	204_K	0.511	0.79
461_I	464_S	0.510	0.79
238_R	242_G	0.510	0.79
364_N	368_I	0.509	0.79
222_N	238_R	0.509	0.79
380_I	394_F	0.508	0.79
446_A	452_S	0.508	0.79
475_E	484_V	0.507	0.79
221_S	303_E	0.507	0.79
355_G	358_V	0.507	0.79
12_I	459_K	0.507	0.79
7_I	41_A	0.507	0.79
58_G	63_E	0.506	0.79
312_L	323_I	0.506	0.79
80_C	92_I	0.506	0.79
480_V	506_H	0.505	0.79
230_L	257_I	0.505	0.79
456_L	459_K	0.504	0.78
519_Y	543_A	0.504	0.78
56_R	62_A	0.504	0.78
287_N	291_E	0.504	0.78
453_R	504_I	0.503	0.78
44_L	549_I	0.503	0.78
106_C	115_I	0.503	0.78
182_S	186_M	0.503	0.78
122_G	133_D	0.502	0.78
310_K	314_R	0.502	0.78
453_R	476_V	0.501	0.78
68_F	80_C	0.500	0.78

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ad8A	1	0.783	100	0.315	Contact Map
4abyA	1	0.6372	100	0.46	Contact Map
4ux3A	1	0.7344	100	0.479	Contact Map
3zgxA	2	0.5903	100	0.525	Contact Map
1w1wA	2	0.5434	100	0.573	Contact Map
3auyA	2	0.6024	100	0.583	Contact Map
4i99A	2	0.5382	100	0.639	Contact Map
3qf7A	2	0.5729	100	0.682	Contact Map
3qktA	2	0.5469	100	0.686	Contact Map
2o5vA	1	0.5955	100	0.708	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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