IF2 - BACSU - GREMLIN Contacts

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IF2 - Translation initiation factor IF-2

UniProt:	P17889	Sequences: MAKMRVYEYAKALNVSSKEILTALKNMDLEVNNHMAMLEEKAIKKLDAKYKKGGARAKSQKPAETNKNKQPQGVNQQSAGNQPNKIRDGKKNDVQNNQFNKNKKNNNNKKNKRNNNNNKNQHQQKPVKPKKELPEKITFSGTLTVGALAEELGKEPSELIKKLMLLGVMATINQELDKDTIELIASEYGVETEEVIVLEETELEKYEEPDNEEDLEIRPPVVTIMGHVDHGKTTLLDSIRKTKVVEGEAGGITQHIGAYQIEENGKKITFLDTPGHAAFTTMRARGAEVTDITILVVAADDGVMPQTVEAINHAKAAEVPIIVAVNKIDKESANPDRVMQELTEYGLVPEAWGGETIFVPLSALTGKGIDELVEMILLVSEVEELKANPNRQAKGTVIEAELDKGRGSVATLLVQTGTLHVGDPIVVGNTFGRVRAMVNDIGRRVKTAGPSTPVEITGLNDVPQAGDQFLVFKDEKTARSVGEARASKQLEEQRSDKAKLSLDDLFEQIKQGDVKDINLIVKADVQGSAEALTAALQKIEVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDGNAKSTAEAENVDIRLHRIIYKVIDEIEAAMKGMLDPEYEEKVIGQVEVRQTFKVSKIGTIAGGYVTEGTITRDSGLRLIRDGVVIFEGEVDVLKRFKDDVKEVSQGYECGITIKKYNDIREGDILEAFVMQEIERT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	716 (646)
Sequences:	3841 (2024)
Seq/√Len:	79.6

ECOLI - IF2
BACSU - IF2
HALSA - IF2P
SULSO - IF2P

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
294_I	376_I	6.987	1.00
439_N	443_R	4.887	1.00
308_V	345_Y	4.832	1.00
266_K	381_E	4.673	1.00
561_I	571_V	4.637	1.00
630_Q	701_E	3.978	1.00
238_S	366_G	3.807	1.00
523_A	529_A	3.794	1.00
357_I	375_M	3.705	1.00
655_G	669_E	3.635	1.00
368_G	371_E	3.605	1.00
621_K	711_Q	3.560	1.00
669_E	694_K	3.556	1.00
667_E	708_F	3.508	1.00
420_H	447_T	3.453	1.00
631_T	639_T	3.371	1.00
238_S	369_I	3.320	1.00
339_M	351_A	3.278	1.00
177_D	180_T	3.267	1.00
556_I	573_G	3.096	1.00
339_M	360_P	3.042	1.00
532_L	602_V	2.915	1.00
649_T	684_S	2.876	1.00
623_I	654_S	2.856	1.00
658_L	693_I	2.845	1.00
241_K	366_G	2.793	1.00
629_R	644_Y	2.769	1.00
379_V	383_E	2.736	1.00
430_T	461_D	2.685	1.00
651_T	709_V	2.658	1.00
670_V	691_I	2.639	1.00
325_V	358_F	2.599	1.00
289_V	396_T	2.594	1.00
300_D	330_K	2.575	1.00
607_E	611_K	2.549	1.00
601_K	604_D	2.515	1.00
322_I	376_I	2.500	1.00
210_D	388_N	2.450	1.00
391_R	416_T	2.422	1.00
43_I	47_D	2.418	1.00
47_D	51_K	2.377	1.00
328_I	367_K	2.345	1.00
255_H	525_V	2.307	1.00
448_A	454_V	2.265	1.00
44_K	48_A	2.257	1.00
308_V	312_N	2.253	1.00
312_N	550_H	2.245	1.00
343_T	348_V	2.244	1.00
295_L	323_V	2.202	1.00
596_H	605_E	2.178	1.00
325_V	360_P	2.173	1.00
586_A	593_I	2.166	1.00
343_T	352_W	2.162	1.00
217_I	266_K	2.154	1.00
326_N	363_A	2.150	1.00
618_Y	710_M	2.148	1.00
628_V	639_T	2.133	1.00
627_E	702_G	2.133	1.00
314_A	321_I	2.127	1.00
39_E	42_A	2.088	1.00
334_N	340_Q	2.063	1.00
239_I	369_I	2.052	1.00
315_K	346_G	2.049	1.00
626_V	650_I	2.036	1.00
474_D	477_T	2.034	1.00
565_S	589_E	2.008	1.00
360_P	367_K	2.006	1.00
138_T	193_E	2.005	1.00
625_Q	647_E	1.994	1.00
51_K	55_A	1.977	1.00
412_L	469_F	1.962	1.00
39_E	43_I	1.935	1.00
635_S	692_T	1.930	1.00
655_G	708_F	1.918	1.00
674_K	679_D	1.889	1.00
646_T	704_I	1.880	1.00
321_I	347_L	1.869	1.00
672_V	692_T	1.866	1.00
260_Q	267_K	1.862	1.00
349_P	358_F	1.858	1.00
350_E	357_I	1.847	1.00
136_K	193_E	1.842	1.00
621_K	709_V	1.836	1.00
659_I	664_V	1.822	1.00
211_N	214_D	1.816	1.00
337_R	341_E	1.803	1.00
136_K	191_E	1.787	1.00
40_E	44_K	1.770	1.00
365_T	368_G	1.767	1.00
347_L	356_T	1.766	1.00
650_I	691_I	1.758	1.00
49_K	53_G	1.745	1.00
216_E	390_N	1.740	1.00
148_L	152_L	1.730	1.00
262_E	267_K	1.729	1.00
650_I	707_A	1.712	1.00
216_E	389_P	1.711	1.00
604_D	607_E	1.707	1.00
186_S	191_E	1.693	1.00
449_G	452_T	1.671	1.00
680_V	683_V	1.651	1.00
341_E	344_E	1.645	1.00
260_Q	452_T	1.633	1.00
515_K	615_D	1.631	1.00
328_I	368_G	1.625	1.00
366_G	369_I	1.618	1.00
47_D	50_Y	1.610	1.00
201_T	204_E	1.604	1.00
302_G	341_E	1.599	1.00
425_I	459_L	1.596	1.00
214_D	388_N	1.589	1.00
631_T	640_I	1.585	1.00
50_Y	54_G	1.578	1.00
152_L	190_V	1.570	1.00
263_E	266_K	1.569	1.00
61_K	65_T	1.569	1.00
214_D	390_N	1.560	1.00
185_A	192_T	1.542	0.99
644_Y	688_E	1.537	0.99
159_L	184_I	1.536	0.99
126_P	129_P	1.534	0.99
328_I	335_P	1.530	0.99
392_Q	473_K	1.520	0.99
584_S	588_A	1.502	0.99
46_L	50_Y	1.500	0.99
311_I	345_Y	1.496	0.99
671_D	694_K	1.496	0.99
561_I	593_I	1.495	0.99
45_K	49_K	1.493	0.99
43_I	51_K	1.488	0.99
55_A	59_S	1.486	0.99
58_K	62_P	1.479	0.99
643_G	689_C	1.473	0.99
634_V	637_I	1.470	0.99
162_K	188_Y	1.465	0.99
58_K	61_K	1.460	0.99
658_L	696_Y	1.456	0.99
658_L	699_I	1.453	0.99
572_I	602_V	1.443	0.99
54_G	58_K	1.439	0.99
445_V	454_V	1.436	0.99
654_S	707_A	1.434	0.99
675_R	683_V	1.428	0.99
504_D	507_E	1.424	0.99
349_P	356_T	1.417	0.99
656_L	693_I	1.413	0.99
541_V	610_M	1.410	0.99
623_I	707_A	1.398	0.99
312_N	315_K	1.392	0.99
260_Q	269_T	1.392	0.99
296_V	361_L	1.391	0.99
520_I	571_V	1.388	0.99
53_G	57_A	1.384	0.99
643_G	691_I	1.382	0.99
47_D	55_A	1.381	0.99
50_Y	53_G	1.378	0.99
178_K	194_E	1.373	0.99
238_S	365_T	1.367	0.99
617_E	713_I	1.367	0.99
555_A	662_G	1.364	0.99
42_A	46_L	1.364	0.99
668_G	693_I	1.363	0.99
598_I	602_V	1.362	0.99
626_V	707_A	1.358	0.99
239_I	373_V	1.358	0.99
54_G	62_P	1.342	0.98
176_L	181_I	1.340	0.98
398_I	411_T	1.340	0.98
388_N	391_R	1.340	0.98
634_V	692_T	1.339	0.98
584_S	587_E	1.336	0.98
146_G	150_E	1.336	0.98
619_E	713_I	1.335	0.98
490_L	494_R	1.331	0.98
52_K	55_A	1.325	0.98
43_I	50_Y	1.321	0.98
56_R	60_Q	1.319	0.98
43_I	55_A	1.308	0.98
38_L	43_I	1.306	0.98
210_D	214_D	1.304	0.98
533_T	551_T	1.297	0.98
335_P	360_P	1.293	0.98
583_K	587_E	1.292	0.98
643_G	670_V	1.289	0.98
619_E	711_Q	1.285	0.98
436_A	457_T	1.283	0.98
674_K	680_V	1.280	0.98
626_V	643_G	1.275	0.98
425_I	456_I	1.266	0.98
351_A	360_P	1.265	0.98
421_V	446_K	1.254	0.98
517_I	613_M	1.252	0.98
243_K	370_D	1.252	0.98
573_G	595_L	1.249	0.98
357_I	379_V	1.248	0.98
48_A	56_R	1.242	0.97
110_K	113_R	1.238	0.97
360_P	371_E	1.236	0.97
223_T	293_T	1.229	0.97
39_E	47_D	1.226	0.97
691_I	705_L	1.225	0.97
113_R	117_N	1.221	0.97
47_D	54_G	1.221	0.97
623_I	709_V	1.218	0.97
160_I	164_M	1.216	0.97
659_I	662_G	1.216	0.97
628_V	705_L	1.216	0.97
144_T	147_A	1.207	0.97
202_E	205_K	1.205	0.97
48_A	52_K	1.199	0.97
622_V	647_E	1.198	0.97
164_M	169_M	1.196	0.97
178_K	181_I	1.192	0.97
649_T	682_E	1.187	0.97
535_A	603_I	1.178	0.97
61_K	64_E	1.178	0.97
630_Q	676_F	1.177	0.96
364_L	367_K	1.177	0.96
683_V	689_C	1.176	0.96
402_L	462_V	1.173	0.96
162_K	165_L	1.170	0.96
336_D	360_P	1.170	0.96
56_R	59_S	1.169	0.96
303_V	358_F	1.169	0.96
38_L	42_A	1.161	0.96
585_T	589_E	1.161	0.96
210_D	391_R	1.158	0.96
516_D	547_K	1.158	0.96
41_K	44_K	1.155	0.96
108_N	111_N	1.155	0.96
487_S	491_E	1.153	0.96
108_N	117_N	1.150	0.96
402_L	408_S	1.147	0.96
105_N	109_K	1.145	0.96
670_V	693_I	1.141	0.96
243_K	246_E	1.140	0.96
51_K	59_S	1.134	0.96
533_T	537_Q	1.134	0.96
656_L	670_V	1.133	0.96
661_D	700_R	1.130	0.96
415_Q	451_S	1.128	0.96
408_S	462_V	1.128	0.96
38_L	46_L	1.126	0.95
39_E	46_L	1.125	0.95
52_K	56_R	1.123	0.95
166_L	183_L	1.123	0.95
39_E	55_A	1.114	0.95
651_T	654_S	1.112	0.95
605_E	608_A	1.111	0.95
40_E	52_K	1.108	0.95
521_V	533_T	1.108	0.95
401_E	455_E	1.104	0.95
40_E	48_A	1.094	0.95
45_K	53_G	1.081	0.94
55_A	63_A	1.080	0.94
43_I	46_L	1.079	0.94
425_I	469_F	1.076	0.94
521_V	529_A	1.075	0.94
277_A	538_K	1.075	0.94
48_A	51_K	1.072	0.94
622_V	659_I	1.070	0.94
109_K	114_N	1.070	0.94
339_M	358_F	1.065	0.94
518_N	547_K	1.063	0.94
126_P	130_K	1.063	0.94
40_E	43_I	1.062	0.94
143_L	181_I	1.061	0.94
514_V	545_K	1.057	0.94
116_N	120_N	1.056	0.94
395_G	469_F	1.055	0.94
359_V	375_M	1.047	0.93
639_T	697_N	1.046	0.93
43_I	54_G	1.045	0.93
39_E	50_Y	1.044	0.93
49_K	55_A	1.044	0.93
42_A	50_Y	1.044	0.93
262_E	265_G	1.042	0.93
41_K	47_D	1.042	0.93
59_S	64_E	1.036	0.93
41_K	49_K	1.035	0.93
388_N	416_T	1.031	0.93
52_K	58_K	1.030	0.93
443_R	446_K	1.030	0.93
601_K	608_A	1.028	0.93
394_K	416_T	1.023	0.93
41_K	45_K	1.022	0.93
158_E	161_K	1.022	0.93
389_P	418_T	1.019	0.92
42_A	49_K	1.014	0.92
215_L	388_N	1.012	0.92
633_K	639_T	1.010	0.92
110_K	114_N	1.010	0.92
488_K	491_E	1.008	0.92
578_P	595_L	1.008	0.92
42_A	45_K	1.008	0.92
271_L	281_T	1.004	0.92
59_S	63_A	1.004	0.92
51_K	54_G	1.003	0.92
179_D	183_L	0.999	0.92
359_V	371_E	0.999	0.92
427_V	459_L	0.997	0.92
293_T	310_A	0.991	0.91
658_L	705_L	0.990	0.91
234_T	238_S	0.989	0.91
48_A	55_A	0.988	0.91
598_I	601_K	0.988	0.91
62_P	66_N	0.986	0.91
667_E	705_L	0.986	0.91
629_R	687_Y	0.980	0.91
62_P	65_T	0.979	0.91
328_I	360_P	0.974	0.91
561_I	586_A	0.974	0.91
533_T	548_I	0.974	0.91
597_R	667_E	0.973	0.91
57_A	62_P	0.972	0.90
49_K	57_A	0.967	0.90
318_E	346_G	0.966	0.90
281_T	534_A	0.964	0.90
49_K	54_G	0.963	0.90
112_K	120_N	0.961	0.90
106_N	118_N	0.961	0.90
647_E	685_Q	0.960	0.90
502_L	609_A	0.960	0.90
171_T	174_Q	0.957	0.90
44_K	51_K	0.955	0.90
152_L	155_E	0.953	0.90
224_I	376_I	0.952	0.90
543_G	615_D	0.951	0.90
626_V	654_S	0.948	0.89
123_Q	126_P	0.947	0.89
106_N	115_N	0.947	0.89
349_P	352_W	0.946	0.89
611_K	714_E	0.943	0.89
360_P	368_G	0.942	0.89
224_I	369_I	0.941	0.89
100_N	103_K	0.941	0.89
119_K	122_H	0.940	0.89
58_K	65_T	0.940	0.89
498_A	504_D	0.937	0.89
49_K	52_K	0.935	0.89
60_Q	65_T	0.933	0.89
393_A	419_L	0.932	0.89
666_F	700_R	0.930	0.88
42_A	47_D	0.924	0.88
357_I	382_V	0.924	0.88
670_V	707_A	0.924	0.88
38_L	41_K	0.923	0.88
57_A	61_K	0.922	0.88
628_V	658_L	0.921	0.88
221_V	413_L	0.920	0.88
156_P	160_I	0.920	0.88
105_N	108_N	0.919	0.88
222_V	268_I	0.918	0.88
426_V	472_F	0.916	0.88
437_M	448_A	0.915	0.88
625_Q	704_I	0.914	0.88
109_K	113_R	0.913	0.88
604_D	608_A	0.913	0.88
639_T	699_I	0.912	0.87
562_I	565_S	0.911	0.87
656_L	707_A	0.908	0.87
310_A	313_H	0.907	0.87
223_T	319_V	0.906	0.87
43_I	49_K	0.905	0.87
292_I	322_I	0.904	0.87
111_N	115_N	0.903	0.87
162_K	166_L	0.901	0.87
38_L	49_K	0.901	0.87
628_V	693_I	0.898	0.87
581_N	584_S	0.895	0.86
119_K	123_Q	0.894	0.86
57_A	60_Q	0.892	0.86
50_Y	57_A	0.892	0.86
112_K	116_N	0.891	0.86
40_E	50_Y	0.889	0.86
644_Y	687_Y	0.887	0.86
308_V	343_T	0.887	0.86
180_T	183_L	0.886	0.86
396_T	415_Q	0.885	0.86
119_K	127_V	0.883	0.86
489_Q	493_Q	0.882	0.86
55_A	64_E	0.881	0.86
52_K	60_Q	0.881	0.86
635_S	674_K	0.880	0.86
54_G	59_S	0.880	0.86
611_K	618_Y	0.879	0.85
243_K	441_I	0.878	0.85
117_N	121_Q	0.878	0.85
346_G	355_E	0.875	0.85
429_N	486_A	0.875	0.85
107_N	111_N	0.874	0.85
224_I	322_I	0.873	0.85
39_E	49_K	0.873	0.85
46_L	49_K	0.868	0.85
124_Q	129_P	0.868	0.85
666_F	695_K	0.868	0.85
659_I	663_V	0.868	0.85
106_N	110_K	0.865	0.85
38_L	65_T	0.864	0.84
577_R	663_V	0.862	0.84
122_H	125_K	0.861	0.84
105_N	110_K	0.861	0.84
41_K	48_A	0.861	0.84
123_Q	127_V	0.859	0.84
170_A	174_Q	0.857	0.84
675_R	687_Y	0.856	0.84
183_L	187_E	0.855	0.84
108_N	112_K	0.855	0.84
39_E	51_K	0.853	0.84
536_L	606_I	0.852	0.84
50_Y	55_A	0.851	0.84
51_K	65_T	0.850	0.84
60_Q	64_E	0.850	0.84
670_V	705_L	0.850	0.84
684_S	687_Y	0.848	0.83
597_R	601_K	0.847	0.83
45_K	48_A	0.846	0.83
623_I	649_T	0.845	0.83
397_V	427_V	0.842	0.83
427_V	430_T	0.841	0.83
138_T	195_V	0.841	0.83
115_N	118_N	0.840	0.83
125_K	129_P	0.840	0.83
456_I	459_L	0.837	0.83
58_K	66_N	0.836	0.82
234_T	245_V	0.836	0.82
46_L	55_A	0.835	0.82
268_I	322_I	0.832	0.82
615_D	618_Y	0.831	0.82
424_P	479_R	0.830	0.82
437_M	456_I	0.830	0.82
44_K	47_D	0.830	0.82
104_K	107_N	0.830	0.82
111_N	116_N	0.827	0.82
655_G	667_E	0.826	0.82
141_G	178_K	0.826	0.82
44_K	49_K	0.825	0.82
120_N	124_Q	0.825	0.82
49_K	58_K	0.825	0.82
221_V	289_V	0.823	0.81
131_K	134_P	0.822	0.81
517_I	610_M	0.821	0.81
333_A	338_V	0.819	0.81
628_V	641_A	0.818	0.81
448_A	452_T	0.817	0.81
628_V	699_I	0.814	0.81
693_I	705_L	0.813	0.81
133_L	136_K	0.813	0.81
182_E	186_S	0.812	0.81
114_N	118_N	0.812	0.81
143_L	151_E	0.812	0.81
55_A	58_K	0.812	0.81
518_N	568_N	0.808	0.80
117_N	120_N	0.808	0.80
53_G	61_K	0.808	0.80
121_Q	125_K	0.807	0.80
561_I	591_V	0.805	0.80
56_R	62_P	0.804	0.80
293_T	314_A	0.803	0.80
58_K	63_A	0.802	0.80
618_Y	712_E	0.801	0.80
393_A	471_V	0.801	0.80
59_S	62_P	0.800	0.80
521_V	534_A	0.800	0.80
121_Q	124_Q	0.800	0.80
436_A	444_R	0.799	0.80
529_A	551_T	0.798	0.79
347_L	357_I	0.797	0.79
54_G	64_E	0.795	0.79
509_I	512_G	0.794	0.79
41_K	50_Y	0.794	0.79
53_G	56_R	0.793	0.79
53_G	58_K	0.791	0.79
107_N	110_K	0.788	0.79
125_K	130_K	0.788	0.79
657_R	706_E	0.787	0.79
48_A	54_G	0.786	0.78
42_A	48_A	0.785	0.78
534_A	537_Q	0.784	0.78
111_N	118_N	0.784	0.78
144_T	171_T	0.783	0.78
448_A	451_S	0.782	0.78
666_F	693_I	0.782	0.78
537_Q	548_I	0.780	0.78
650_I	670_V	0.780	0.78
369_I	373_V	0.780	0.78
110_K	119_K	0.779	0.78
142_T	175_E	0.779	0.78
107_N	119_K	0.778	0.78
627_E	646_T	0.778	0.78
336_D	339_M	0.777	0.78
105_N	111_N	0.777	0.78
405_G	521_V	0.775	0.77
109_K	112_K	0.775	0.77
40_E	45_K	0.773	0.77
529_A	548_I	0.772	0.77
110_K	115_N	0.772	0.77
234_T	364_L	0.771	0.77
113_R	116_N	0.771	0.77
395_G	413_L	0.770	0.77
44_K	52_K	0.770	0.77
295_L	345_Y	0.768	0.77
576_V	582_A	0.768	0.77
44_K	50_Y	0.768	0.77
118_N	122_H	0.767	0.77
579_D	585_T	0.767	0.77
299_A	333_A	0.766	0.77
120_N	123_Q	0.766	0.77
655_G	710_M	0.766	0.77
339_M	349_P	0.766	0.77
430_T	460_N	0.765	0.77
38_L	45_K	0.764	0.76
103_K	112_K	0.763	0.76
56_R	64_E	0.762	0.76
162_K	187_E	0.762	0.76
440_D	445_V	0.762	0.76
477_T	484_A	0.761	0.76
44_K	65_T	0.761	0.76
634_V	674_K	0.760	0.76
106_N	109_K	0.758	0.76
246_E	364_L	0.758	0.76
148_L	181_I	0.757	0.76
56_R	61_K	0.756	0.76
41_K	53_G	0.755	0.76
322_I	359_V	0.754	0.76
580_G	583_K	0.754	0.76
103_K	113_R	0.754	0.76
52_K	64_E	0.752	0.75
521_V	602_V	0.752	0.75
55_A	66_N	0.751	0.75
343_T	349_P	0.751	0.75
359_V	368_G	0.748	0.75
108_N	115_N	0.748	0.75
622_V	625_Q	0.748	0.75
438_V	444_R	0.746	0.75
38_L	53_G	0.745	0.75
350_E	375_M	0.744	0.75
152_L	188_Y	0.744	0.75
39_E	54_G	0.743	0.74
51_K	58_K	0.743	0.74
103_K	106_N	0.743	0.74
129_P	134_P	0.743	0.74
280_T	566_A	0.741	0.74
631_T	701_E	0.740	0.74
101_K	104_K	0.740	0.74
139_F	181_I	0.740	0.74
38_L	47_D	0.739	0.74
182_E	192_T	0.739	0.74
223_T	320_P	0.738	0.74
249_A	597_R	0.737	0.74
125_K	128_K	0.736	0.74
134_P	190_V	0.736	0.74
210_D	215_L	0.735	0.74
625_Q	646_T	0.735	0.74
42_A	61_K	0.735	0.74
161_K	165_L	0.735	0.74
440_D	452_T	0.734	0.74
105_N	117_N	0.733	0.73
132_E	135_E	0.733	0.73
40_E	47_D	0.732	0.73
561_I	582_A	0.732	0.73
203_L	206_Y	0.730	0.73
675_R	680_V	0.730	0.73
539_I	543_G	0.730	0.73
361_L	364_L	0.730	0.73
162_K	184_I	0.727	0.73
571_V	593_I	0.727	0.73
618_Y	714_E	0.727	0.73
391_R	418_T	0.726	0.73
57_A	63_A	0.725	0.73
598_I	606_I	0.725	0.73
210_D	213_E	0.721	0.72
421_V	444_R	0.721	0.72
334_N	337_R	0.720	0.72
432_G	459_L	0.719	0.72
579_D	582_A	0.718	0.72
41_K	52_K	0.718	0.72
504_D	508_Q	0.718	0.72
47_D	65_T	0.717	0.72
43_I	65_T	0.715	0.72
315_K	345_Y	0.714	0.71
201_T	205_K	0.714	0.71
104_K	109_K	0.714	0.71
104_K	110_K	0.713	0.71
313_H	317_A	0.713	0.71
635_S	639_T	0.713	0.71
140_S	151_E	0.713	0.71
367_K	371_E	0.712	0.71
39_E	52_K	0.712	0.71
631_T	699_I	0.712	0.71
128_K	132_E	0.712	0.71
46_L	54_G	0.711	0.71
424_P	482_G	0.711	0.71
47_D	53_G	0.710	0.71
579_D	584_S	0.710	0.71
111_N	114_N	0.709	0.71
654_S	709_V	0.708	0.71
154_K	159_L	0.708	0.71
336_D	352_W	0.705	0.71
42_A	54_G	0.705	0.71
46_L	53_G	0.704	0.70
45_K	52_K	0.703	0.70
46_L	65_T	0.703	0.70
345_Y	356_T	0.703	0.70
108_N	113_R	0.699	0.70
431_F	460_N	0.699	0.70
187_E	190_V	0.699	0.70
116_N	119_K	0.699	0.70
115_N	120_N	0.698	0.70
501_S	504_D	0.697	0.70
178_K	182_E	0.696	0.70
244_V	247_G	0.694	0.69
238_S	241_K	0.690	0.69
529_A	533_T	0.689	0.69
623_I	655_G	0.688	0.69
632_F	668_G	0.687	0.69
544_V	613_M	0.687	0.69
356_T	375_M	0.686	0.68
112_K	118_N	0.685	0.68
112_K	115_N	0.684	0.68
308_V	311_I	0.683	0.68
57_A	64_E	0.683	0.68
143_L	147_A	0.683	0.68
316_A	518_N	0.683	0.68
42_A	53_G	0.682	0.68
51_K	62_P	0.681	0.68
340_Q	343_T	0.681	0.68
292_I	380_S	0.681	0.68
609_A	612_G	0.680	0.68
118_N	121_Q	0.679	0.68
217_I	384_E	0.677	0.67
40_E	55_A	0.677	0.67
41_K	55_A	0.677	0.67
57_A	65_T	0.675	0.67
103_K	107_N	0.675	0.67
594_R	605_E	0.673	0.67
56_R	63_A	0.673	0.67
108_N	120_N	0.673	0.67
102_N	105_N	0.673	0.67
311_I	342_L	0.673	0.67
499_K	565_S	0.672	0.67
185_A	190_V	0.672	0.67
299_A	328_I	0.672	0.67
122_H	126_P	0.672	0.67
297_V	342_L	0.672	0.67
109_K	116_N	0.671	0.67
105_N	113_R	0.671	0.67
144_T	176_L	0.671	0.67
186_S	189_G	0.671	0.67
54_G	61_K	0.670	0.67
652_R	679_D	0.670	0.67
176_L	590_N	0.670	0.67
42_A	57_A	0.670	0.67
55_A	65_T	0.670	0.67
49_K	65_T	0.669	0.67
425_I	434_V	0.665	0.66
111_N	117_N	0.665	0.66
255_H	411_T	0.665	0.66
103_K	109_K	0.664	0.66
483_E	486_A	0.664	0.66
106_N	111_N	0.663	0.66
118_N	125_K	0.663	0.66
269_T	452_T	0.663	0.66
467_D	477_T	0.663	0.66
479_R	483_E	0.662	0.66
124_Q	130_K	0.662	0.66
148_L	159_L	0.660	0.65
119_K	126_P	0.659	0.65
45_K	50_Y	0.659	0.65
504_D	509_I	0.657	0.65
576_V	712_E	0.656	0.65
259_Y	269_T	0.656	0.65
607_E	618_Y	0.656	0.65
54_G	65_T	0.655	0.65
103_K	110_K	0.655	0.65
109_K	118_N	0.653	0.65
53_G	63_A	0.651	0.64
219_P	452_T	0.651	0.64
38_L	55_A	0.651	0.64
208_E	421_V	0.650	0.64
110_K	117_N	0.650	0.64
528_S	598_I	0.650	0.64
673_L	679_D	0.650	0.64
221_V	415_Q	0.649	0.64
520_I	552_G	0.649	0.64
339_M	343_T	0.648	0.64
348_V	358_F	0.647	0.64
163_L	168_V	0.647	0.64
375_M	379_V	0.647	0.64
467_D	691_I	0.645	0.64
627_E	704_I	0.643	0.63
289_V	398_I	0.642	0.63
160_I	172_I	0.641	0.63
108_N	114_N	0.641	0.63
304_M	338_V	0.641	0.63
63_A	66_N	0.640	0.63
160_I	173_N	0.640	0.63
52_K	59_S	0.640	0.63
109_K	121_Q	0.639	0.63
323_V	347_L	0.639	0.63
113_R	119_K	0.638	0.63
145_V	159_L	0.638	0.63
102_N	110_K	0.638	0.63
42_A	65_T	0.637	0.63
38_L	59_S	0.637	0.63
54_G	57_A	0.636	0.63
572_I	606_I	0.635	0.62
110_K	120_N	0.634	0.62
148_L	185_A	0.633	0.62
120_N	125_K	0.633	0.62
423_D	471_V	0.633	0.62
212_E	215_L	0.633	0.62
140_S	143_L	0.632	0.62
631_T	692_T	0.631	0.62
219_P	267_K	0.631	0.62
121_Q	126_P	0.631	0.62
184_I	188_Y	0.630	0.62
38_L	50_Y	0.628	0.62
434_V	456_I	0.628	0.62
59_S	65_T	0.626	0.61
106_N	114_N	0.626	0.61
144_T	148_L	0.625	0.61
432_G	471_V	0.623	0.61
107_N	117_N	0.622	0.61
155_E	158_E	0.621	0.61
392_Q	471_V	0.621	0.61
40_E	53_G	0.621	0.61
181_I	184_I	0.619	0.61
42_A	62_P	0.619	0.61
55_A	60_Q	0.618	0.60
202_E	206_Y	0.617	0.60
534_A	538_K	0.617	0.60
474_D	588_A	0.617	0.60
107_N	114_N	0.616	0.60
108_N	121_Q	0.616	0.60
155_E	379_V	0.615	0.60
146_G	149_A	0.615	0.60
60_Q	66_N	0.614	0.60
608_A	714_E	0.614	0.60
312_N	552_G	0.613	0.60
516_D	545_K	0.613	0.60
429_N	489_Q	0.612	0.60
58_K	64_E	0.612	0.60
41_K	46_L	0.611	0.60
400_A	526_Q	0.611	0.60
38_L	56_R	0.609	0.59
235_L	361_L	0.609	0.59
182_E	194_E	0.608	0.59
312_N	345_Y	0.608	0.59
48_A	53_G	0.608	0.59
406_R	409_V	0.608	0.59
54_G	60_Q	0.607	0.59
555_A	577_R	0.607	0.59
60_Q	63_A	0.607	0.59
550_H	560_D	0.606	0.59
105_N	112_K	0.605	0.59
573_G	578_P	0.605	0.59
164_M	171_T	0.605	0.59
183_L	191_E	0.605	0.59
242_T	441_I	0.605	0.59
401_E	411_T	0.605	0.59
40_E	46_L	0.604	0.59
336_D	340_Q	0.603	0.59
102_N	106_N	0.603	0.59
150_E	153_G	0.602	0.58
646_T	685_Q	0.601	0.58
122_H	130_K	0.601	0.58
49_K	56_R	0.600	0.58
50_Y	58_K	0.600	0.58
103_K	111_N	0.600	0.58
135_E	152_L	0.600	0.58
637_I	674_K	0.599	0.58
168_V	184_I	0.598	0.58
109_K	120_N	0.598	0.58
610_M	614_L	0.597	0.58
43_I	52_K	0.596	0.58
164_M	170_A	0.596	0.58
53_G	65_T	0.595	0.58
44_K	56_R	0.595	0.58
295_L	342_L	0.594	0.57
492_E	495_S	0.593	0.57
103_K	108_N	0.593	0.57
406_R	457_T	0.593	0.57
499_K	568_N	0.592	0.57
99_F	104_K	0.592	0.57
106_N	120_N	0.591	0.57
541_V	607_E	0.590	0.57
47_D	52_K	0.590	0.57
539_I	611_K	0.590	0.57
472_F	477_T	0.588	0.57
626_V	691_I	0.587	0.56
149_A	152_L	0.587	0.56
464_Q	467_D	0.585	0.56
154_K	190_V	0.585	0.56
145_V	170_A	0.584	0.56
643_G	683_V	0.584	0.56
634_V	640_I	0.583	0.56
313_H	563_L	0.583	0.56
116_N	124_Q	0.582	0.56
293_T	379_V	0.582	0.56
521_V	548_I	0.582	0.56
55_A	62_P	0.581	0.56
610_M	613_M	0.581	0.56
109_K	119_K	0.580	0.56
127_V	134_P	0.580	0.56
640_I	692_T	0.580	0.56
562_I	585_T	0.579	0.55
644_Y	686_G	0.579	0.55
40_E	56_R	0.577	0.55
53_G	59_S	0.576	0.55
405_G	409_V	0.575	0.55
377_L	380_S	0.575	0.55
680_V	692_T	0.575	0.55
129_P	133_L	0.575	0.55
51_K	63_A	0.573	0.55
224_I	242_T	0.573	0.55
104_K	108_N	0.573	0.55
62_P	98_Q	0.572	0.55
99_F	103_K	0.571	0.54
48_A	60_Q	0.571	0.54
312_N	316_A	0.570	0.54
540_E	697_N	0.570	0.54
99_F	102_N	0.568	0.54
339_M	371_E	0.568	0.54
53_G	60_Q	0.567	0.54
268_I	376_I	0.567	0.54
115_N	121_Q	0.566	0.54
100_N	108_N	0.566	0.54
639_T	693_I	0.566	0.54
224_I	259_Y	0.566	0.54
671_D	692_T	0.565	0.54
120_N	126_P	0.565	0.54
315_K	355_E	0.565	0.54
438_V	457_T	0.564	0.54
107_N	115_N	0.564	0.54
104_K	113_R	0.564	0.54
477_T	480_S	0.563	0.53
661_D	664_V	0.563	0.53
580_G	584_S	0.561	0.53
573_G	576_V	0.560	0.53
224_I	360_P	0.559	0.53
585_T	588_A	0.559	0.53
145_V	149_A	0.558	0.53
508_Q	568_N	0.558	0.53
114_N	117_N	0.558	0.53
497_K	501_S	0.556	0.53
115_N	119_K	0.556	0.53
216_E	386_K	0.556	0.53
637_I	656_L	0.555	0.52
38_L	61_K	0.555	0.52
41_K	65_T	0.555	0.52
50_Y	65_T	0.554	0.52
630_Q	635_S	0.553	0.52
644_Y	685_Q	0.553	0.52
271_L	529_A	0.553	0.52
474_D	679_D	0.553	0.52
223_T	289_V	0.552	0.52
644_Y	675_R	0.552	0.52
47_D	59_S	0.551	0.52
43_I	56_R	0.551	0.52
519_L	536_L	0.551	0.52
213_E	388_N	0.550	0.52
673_L	691_I	0.550	0.52
45_K	57_A	0.547	0.51
107_N	112_K	0.547	0.51
126_P	133_L	0.547	0.51
44_K	55_A	0.546	0.51
45_K	62_P	0.545	0.51
52_K	57_A	0.545	0.51
400_A	549_I	0.545	0.51
183_L	186_S	0.544	0.51
265_G	374_E	0.543	0.51
49_K	64_E	0.542	0.51
39_E	48_A	0.541	0.51
675_R	686_G	0.541	0.51
108_N	116_N	0.541	0.51
361_L	368_G	0.541	0.51
140_S	181_I	0.541	0.51
109_K	117_N	0.541	0.51
45_K	56_R	0.540	0.50
100_N	104_K	0.540	0.50
455_E	610_M	0.540	0.50
488_K	498_A	0.539	0.50
477_T	481_V	0.539	0.50
109_K	115_N	0.539	0.50
127_V	131_K	0.539	0.50
107_N	116_N	0.539	0.50
421_V	438_V	0.539	0.50
360_P	366_G	0.538	0.50
398_I	533_T	0.538	0.50
324_A	361_L	0.537	0.50
129_P	136_K	0.537	0.50
113_R	118_N	0.536	0.50
51_K	56_R	0.536	0.50
38_L	54_G	0.535	0.50
110_K	118_N	0.535	0.50
346_G	349_P	0.534	0.50
39_E	44_K	0.534	0.50
154_K	158_E	0.533	0.50
55_A	61_K	0.533	0.50
114_N	122_H	0.533	0.50
42_A	58_K	0.532	0.49
157_S	160_I	0.532	0.49
271_L	525_V	0.532	0.49
352_W	356_T	0.529	0.49
157_S	161_K	0.528	0.49
111_N	119_K	0.528	0.49
54_G	66_N	0.528	0.49
643_G	673_L	0.528	0.49
596_H	601_K	0.527	0.49
127_V	130_K	0.527	0.49
158_E	162_K	0.526	0.49
251_G	301_D	0.526	0.49
340_Q	346_G	0.525	0.49
201_T	206_Y	0.525	0.49
124_Q	127_V	0.524	0.48
176_L	247_G	0.523	0.48
101_K	105_N	0.522	0.48
387_A	450_P	0.521	0.48
116_N	122_H	0.521	0.48
255_H	271_L	0.521	0.48
238_S	242_T	0.521	0.48
335_P	338_V	0.520	0.48
575_N	664_V	0.520	0.48
132_E	136_K	0.519	0.48
521_V	535_A	0.519	0.48
185_A	189_G	0.519	0.48
49_K	62_P	0.518	0.48
586_A	592_D	0.518	0.48
211_N	215_L	0.518	0.48
400_A	467_D	0.518	0.48
434_V	459_L	0.517	0.47
111_N	120_N	0.517	0.47
215_L	386_K	0.516	0.47
550_H	559_S	0.515	0.47
49_K	59_S	0.514	0.47
112_K	125_K	0.513	0.47
52_K	61_K	0.513	0.47
130_K	133_L	0.513	0.47
426_V	478_A	0.512	0.47
48_A	59_S	0.511	0.47
340_Q	352_W	0.511	0.47
347_L	358_F	0.511	0.47
212_E	388_N	0.510	0.47
219_P	260_Q	0.509	0.46
44_K	59_S	0.509	0.46
643_G	650_I	0.509	0.46
48_A	58_K	0.509	0.46
448_A	453_P	0.508	0.46
146_G	151_E	0.508	0.46
45_K	60_Q	0.508	0.46
489_Q	495_S	0.508	0.46
181_I	185_A	0.508	0.46
594_R	609_A	0.507	0.46
345_Y	349_P	0.507	0.46
148_L	184_I	0.506	0.46
38_L	57_A	0.506	0.46
203_L	470_L	0.506	0.46
340_Q	344_E	0.506	0.46
197_V	200_E	0.506	0.46
313_H	316_A	0.505	0.46
45_K	54_G	0.504	0.46
626_V	692_T	0.504	0.46
50_Y	66_N	0.502	0.46
645_V	650_I	0.501	0.45
41_K	56_R	0.501	0.45
48_A	65_T	0.501	0.45
38_L	44_K	0.501	0.45
500_L	505_L	0.500	0.45

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1zo1I	1	0.6997	100	0.416	Contact Map
3j4jA	1	0.7905	100	0.422	Contact Map
3izyP	1	0.6899	100	0.426	Contact Map
3wbiA	1	0.6494	100	0.477	Contact Map
4n3nA	2	0.6606	100	0.486	Contact Map
4upyB	1	0.7053	100	0.49	Contact Map
1g7sA	1	0.6494	100	0.495	Contact Map
4kjzA	1	0.655	100	0.551	Contact Map
4n3sA	1	0.5182	100	0.591	Contact Map
4b43A	1	0.4791	100	0.732	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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