GREMLIN Database
IF2 - Translation initiation factor IF-2
UniProt: P17889 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 716 (646)
Sequences: 3841 (2024)
Seq/√Len: 79.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
294_I376_I6.9871.00
439_N443_R4.8871.00
308_V345_Y4.8321.00
266_K381_E4.6731.00
561_I571_V4.6371.00
630_Q701_E3.9781.00
238_S366_G3.8071.00
523_A529_A3.7941.00
357_I375_M3.7051.00
655_G669_E3.6351.00
368_G371_E3.6051.00
621_K711_Q3.5601.00
669_E694_K3.5561.00
667_E708_F3.5081.00
420_H447_T3.4531.00
631_T639_T3.3711.00
238_S369_I3.3201.00
339_M351_A3.2781.00
177_D180_T3.2671.00
556_I573_G3.0961.00
339_M360_P3.0421.00
532_L602_V2.9151.00
649_T684_S2.8761.00
623_I654_S2.8561.00
658_L693_I2.8451.00
241_K366_G2.7931.00
629_R644_Y2.7691.00
379_V383_E2.7361.00
430_T461_D2.6851.00
651_T709_V2.6581.00
670_V691_I2.6391.00
325_V358_F2.5991.00
289_V396_T2.5941.00
300_D330_K2.5751.00
607_E611_K2.5491.00
601_K604_D2.5151.00
322_I376_I2.5001.00
210_D388_N2.4501.00
391_R416_T2.4221.00
43_I47_D2.4181.00
47_D51_K2.3771.00
328_I367_K2.3451.00
255_H525_V2.3071.00
448_A454_V2.2651.00
44_K48_A2.2571.00
308_V312_N2.2531.00
312_N550_H2.2451.00
343_T348_V2.2441.00
295_L323_V2.2021.00
596_H605_E2.1781.00
325_V360_P2.1731.00
586_A593_I2.1661.00
343_T352_W2.1621.00
217_I266_K2.1541.00
326_N363_A2.1501.00
618_Y710_M2.1481.00
628_V639_T2.1331.00
627_E702_G2.1331.00
314_A321_I2.1271.00
39_E42_A2.0881.00
334_N340_Q2.0631.00
239_I369_I2.0521.00
315_K346_G2.0491.00
626_V650_I2.0361.00
474_D477_T2.0341.00
565_S589_E2.0081.00
360_P367_K2.0061.00
138_T193_E2.0051.00
625_Q647_E1.9941.00
51_K55_A1.9771.00
412_L469_F1.9621.00
39_E43_I1.9351.00
635_S692_T1.9301.00
655_G708_F1.9181.00
674_K679_D1.8891.00
646_T704_I1.8801.00
321_I347_L1.8691.00
672_V692_T1.8661.00
260_Q267_K1.8621.00
349_P358_F1.8581.00
350_E357_I1.8471.00
136_K193_E1.8421.00
621_K709_V1.8361.00
659_I664_V1.8221.00
211_N214_D1.8161.00
337_R341_E1.8031.00
136_K191_E1.7871.00
40_E44_K1.7701.00
365_T368_G1.7671.00
347_L356_T1.7661.00
650_I691_I1.7581.00
49_K53_G1.7451.00
216_E390_N1.7401.00
148_L152_L1.7301.00
262_E267_K1.7291.00
650_I707_A1.7121.00
216_E389_P1.7111.00
604_D607_E1.7071.00
186_S191_E1.6931.00
449_G452_T1.6711.00
680_V683_V1.6511.00
341_E344_E1.6451.00
260_Q452_T1.6331.00
515_K615_D1.6311.00
328_I368_G1.6251.00
366_G369_I1.6181.00
47_D50_Y1.6101.00
201_T204_E1.6041.00
302_G341_E1.5991.00
425_I459_L1.5961.00
214_D388_N1.5891.00
631_T640_I1.5851.00
50_Y54_G1.5781.00
152_L190_V1.5701.00
263_E266_K1.5691.00
61_K65_T1.5691.00
214_D390_N1.5601.00
185_A192_T1.5420.99
644_Y688_E1.5370.99
159_L184_I1.5360.99
126_P129_P1.5340.99
328_I335_P1.5300.99
392_Q473_K1.5200.99
584_S588_A1.5020.99
46_L50_Y1.5000.99
311_I345_Y1.4960.99
671_D694_K1.4960.99
561_I593_I1.4950.99
45_K49_K1.4930.99
43_I51_K1.4880.99
55_A59_S1.4860.99
58_K62_P1.4790.99
643_G689_C1.4730.99
634_V637_I1.4700.99
162_K188_Y1.4650.99
58_K61_K1.4600.99
658_L696_Y1.4560.99
658_L699_I1.4530.99
572_I602_V1.4430.99
54_G58_K1.4390.99
445_V454_V1.4360.99
654_S707_A1.4340.99
675_R683_V1.4280.99
504_D507_E1.4240.99
349_P356_T1.4170.99
656_L693_I1.4130.99
541_V610_M1.4100.99
623_I707_A1.3980.99
312_N315_K1.3920.99
260_Q269_T1.3920.99
296_V361_L1.3910.99
520_I571_V1.3880.99
53_G57_A1.3840.99
643_G691_I1.3820.99
47_D55_A1.3810.99
50_Y53_G1.3780.99
178_K194_E1.3730.99
238_S365_T1.3670.99
617_E713_I1.3670.99
555_A662_G1.3640.99
42_A46_L1.3640.99
668_G693_I1.3630.99
598_I602_V1.3620.99
626_V707_A1.3580.99
239_I373_V1.3580.99
54_G62_P1.3420.98
176_L181_I1.3400.98
398_I411_T1.3400.98
388_N391_R1.3400.98
634_V692_T1.3390.98
584_S587_E1.3360.98
146_G150_E1.3360.98
619_E713_I1.3350.98
490_L494_R1.3310.98
52_K55_A1.3250.98
43_I50_Y1.3210.98
56_R60_Q1.3190.98
43_I55_A1.3080.98
38_L43_I1.3060.98
210_D214_D1.3040.98
533_T551_T1.2970.98
335_P360_P1.2930.98
583_K587_E1.2920.98
643_G670_V1.2890.98
619_E711_Q1.2850.98
436_A457_T1.2830.98
674_K680_V1.2800.98
626_V643_G1.2750.98
425_I456_I1.2660.98
351_A360_P1.2650.98
421_V446_K1.2540.98
517_I613_M1.2520.98
243_K370_D1.2520.98
573_G595_L1.2490.98
357_I379_V1.2480.98
48_A56_R1.2420.97
110_K113_R1.2380.97
360_P371_E1.2360.97
223_T293_T1.2290.97
39_E47_D1.2260.97
691_I705_L1.2250.97
113_R117_N1.2210.97
47_D54_G1.2210.97
623_I709_V1.2180.97
160_I164_M1.2160.97
659_I662_G1.2160.97
628_V705_L1.2160.97
144_T147_A1.2070.97
202_E205_K1.2050.97
48_A52_K1.1990.97
622_V647_E1.1980.97
164_M169_M1.1960.97
178_K181_I1.1920.97
649_T682_E1.1870.97
535_A603_I1.1780.97
61_K64_E1.1780.97
630_Q676_F1.1770.96
364_L367_K1.1770.96
683_V689_C1.1760.96
402_L462_V1.1730.96
162_K165_L1.1700.96
336_D360_P1.1700.96
56_R59_S1.1690.96
303_V358_F1.1690.96
38_L42_A1.1610.96
585_T589_E1.1610.96
210_D391_R1.1580.96
516_D547_K1.1580.96
41_K44_K1.1550.96
108_N111_N1.1550.96
487_S491_E1.1530.96
108_N117_N1.1500.96
402_L408_S1.1470.96
105_N109_K1.1450.96
670_V693_I1.1410.96
243_K246_E1.1400.96
51_K59_S1.1340.96
533_T537_Q1.1340.96
656_L670_V1.1330.96
661_D700_R1.1300.96
415_Q451_S1.1280.96
408_S462_V1.1280.96
38_L46_L1.1260.95
39_E46_L1.1250.95
52_K56_R1.1230.95
166_L183_L1.1230.95
39_E55_A1.1140.95
651_T654_S1.1120.95
605_E608_A1.1110.95
40_E52_K1.1080.95
521_V533_T1.1080.95
401_E455_E1.1040.95
40_E48_A1.0940.95
45_K53_G1.0810.94
55_A63_A1.0800.94
43_I46_L1.0790.94
425_I469_F1.0760.94
521_V529_A1.0750.94
277_A538_K1.0750.94
48_A51_K1.0720.94
622_V659_I1.0700.94
109_K114_N1.0700.94
339_M358_F1.0650.94
518_N547_K1.0630.94
126_P130_K1.0630.94
40_E43_I1.0620.94
143_L181_I1.0610.94
514_V545_K1.0570.94
116_N120_N1.0560.94
395_G469_F1.0550.94
359_V375_M1.0470.93
639_T697_N1.0460.93
43_I54_G1.0450.93
39_E50_Y1.0440.93
49_K55_A1.0440.93
42_A50_Y1.0440.93
262_E265_G1.0420.93
41_K47_D1.0420.93
59_S64_E1.0360.93
41_K49_K1.0350.93
388_N416_T1.0310.93
52_K58_K1.0300.93
443_R446_K1.0300.93
601_K608_A1.0280.93
394_K416_T1.0230.93
41_K45_K1.0220.93
158_E161_K1.0220.93
389_P418_T1.0190.92
42_A49_K1.0140.92
215_L388_N1.0120.92
633_K639_T1.0100.92
110_K114_N1.0100.92
488_K491_E1.0080.92
578_P595_L1.0080.92
42_A45_K1.0080.92
271_L281_T1.0040.92
59_S63_A1.0040.92
51_K54_G1.0030.92
179_D183_L0.9990.92
359_V371_E0.9990.92
427_V459_L0.9970.92
293_T310_A0.9910.91
658_L705_L0.9900.91
234_T238_S0.9890.91
48_A55_A0.9880.91
598_I601_K0.9880.91
62_P66_N0.9860.91
667_E705_L0.9860.91
629_R687_Y0.9800.91
62_P65_T0.9790.91
328_I360_P0.9740.91
561_I586_A0.9740.91
533_T548_I0.9740.91
597_R667_E0.9730.91
57_A62_P0.9720.90
49_K57_A0.9670.90
318_E346_G0.9660.90
281_T534_A0.9640.90
49_K54_G0.9630.90
112_K120_N0.9610.90
106_N118_N0.9610.90
647_E685_Q0.9600.90
502_L609_A0.9600.90
171_T174_Q0.9570.90
44_K51_K0.9550.90
152_L155_E0.9530.90
224_I376_I0.9520.90
543_G615_D0.9510.90
626_V654_S0.9480.89
123_Q126_P0.9470.89
106_N115_N0.9470.89
349_P352_W0.9460.89
611_K714_E0.9430.89
360_P368_G0.9420.89
224_I369_I0.9410.89
100_N103_K0.9410.89
119_K122_H0.9400.89
58_K65_T0.9400.89
498_A504_D0.9370.89
49_K52_K0.9350.89
60_Q65_T0.9330.89
393_A419_L0.9320.89
666_F700_R0.9300.88
42_A47_D0.9240.88
357_I382_V0.9240.88
670_V707_A0.9240.88
38_L41_K0.9230.88
57_A61_K0.9220.88
628_V658_L0.9210.88
221_V413_L0.9200.88
156_P160_I0.9200.88
105_N108_N0.9190.88
222_V268_I0.9180.88
426_V472_F0.9160.88
437_M448_A0.9150.88
625_Q704_I0.9140.88
109_K113_R0.9130.88
604_D608_A0.9130.88
639_T699_I0.9120.87
562_I565_S0.9110.87
656_L707_A0.9080.87
310_A313_H0.9070.87
223_T319_V0.9060.87
43_I49_K0.9050.87
292_I322_I0.9040.87
111_N115_N0.9030.87
162_K166_L0.9010.87
38_L49_K0.9010.87
628_V693_I0.8980.87
581_N584_S0.8950.86
119_K123_Q0.8940.86
57_A60_Q0.8920.86
50_Y57_A0.8920.86
112_K116_N0.8910.86
40_E50_Y0.8890.86
644_Y687_Y0.8870.86
308_V343_T0.8870.86
180_T183_L0.8860.86
396_T415_Q0.8850.86
119_K127_V0.8830.86
489_Q493_Q0.8820.86
55_A64_E0.8810.86
52_K60_Q0.8810.86
635_S674_K0.8800.86
54_G59_S0.8800.86
611_K618_Y0.8790.85
243_K441_I0.8780.85
117_N121_Q0.8780.85
346_G355_E0.8750.85
429_N486_A0.8750.85
107_N111_N0.8740.85
224_I322_I0.8730.85
39_E49_K0.8730.85
46_L49_K0.8680.85
124_Q129_P0.8680.85
666_F695_K0.8680.85
659_I663_V0.8680.85
106_N110_K0.8650.85
38_L65_T0.8640.84
577_R663_V0.8620.84
122_H125_K0.8610.84
105_N110_K0.8610.84
41_K48_A0.8610.84
123_Q127_V0.8590.84
170_A174_Q0.8570.84
675_R687_Y0.8560.84
183_L187_E0.8550.84
108_N112_K0.8550.84
39_E51_K0.8530.84
536_L606_I0.8520.84
50_Y55_A0.8510.84
51_K65_T0.8500.84
60_Q64_E0.8500.84
670_V705_L0.8500.84
684_S687_Y0.8480.83
597_R601_K0.8470.83
45_K48_A0.8460.83
623_I649_T0.8450.83
397_V427_V0.8420.83
427_V430_T0.8410.83
138_T195_V0.8410.83
115_N118_N0.8400.83
125_K129_P0.8400.83
456_I459_L0.8370.83
58_K66_N0.8360.82
234_T245_V0.8360.82
46_L55_A0.8350.82
268_I322_I0.8320.82
615_D618_Y0.8310.82
424_P479_R0.8300.82
437_M456_I0.8300.82
44_K47_D0.8300.82
104_K107_N0.8300.82
111_N116_N0.8270.82
655_G667_E0.8260.82
141_G178_K0.8260.82
44_K49_K0.8250.82
120_N124_Q0.8250.82
49_K58_K0.8250.82
221_V289_V0.8230.81
131_K134_P0.8220.81
517_I610_M0.8210.81
333_A338_V0.8190.81
628_V641_A0.8180.81
448_A452_T0.8170.81
628_V699_I0.8140.81
693_I705_L0.8130.81
133_L136_K0.8130.81
182_E186_S0.8120.81
114_N118_N0.8120.81
143_L151_E0.8120.81
55_A58_K0.8120.81
518_N568_N0.8080.80
117_N120_N0.8080.80
53_G61_K0.8080.80
121_Q125_K0.8070.80
561_I591_V0.8050.80
56_R62_P0.8040.80
293_T314_A0.8030.80
58_K63_A0.8020.80
618_Y712_E0.8010.80
393_A471_V0.8010.80
59_S62_P0.8000.80
521_V534_A0.8000.80
121_Q124_Q0.8000.80
436_A444_R0.7990.80
529_A551_T0.7980.79
347_L357_I0.7970.79
54_G64_E0.7950.79
509_I512_G0.7940.79
41_K50_Y0.7940.79
53_G56_R0.7930.79
53_G58_K0.7910.79
107_N110_K0.7880.79
125_K130_K0.7880.79
657_R706_E0.7870.79
48_A54_G0.7860.78
42_A48_A0.7850.78
534_A537_Q0.7840.78
111_N118_N0.7840.78
144_T171_T0.7830.78
448_A451_S0.7820.78
666_F693_I0.7820.78
537_Q548_I0.7800.78
650_I670_V0.7800.78
369_I373_V0.7800.78
110_K119_K0.7790.78
142_T175_E0.7790.78
107_N119_K0.7780.78
627_E646_T0.7780.78
336_D339_M0.7770.78
105_N111_N0.7770.78
405_G521_V0.7750.77
109_K112_K0.7750.77
40_E45_K0.7730.77
529_A548_I0.7720.77
110_K115_N0.7720.77
234_T364_L0.7710.77
113_R116_N0.7710.77
395_G413_L0.7700.77
44_K52_K0.7700.77
295_L345_Y0.7680.77
576_V582_A0.7680.77
44_K50_Y0.7680.77
118_N122_H0.7670.77
579_D585_T0.7670.77
299_A333_A0.7660.77
120_N123_Q0.7660.77
655_G710_M0.7660.77
339_M349_P0.7660.77
430_T460_N0.7650.77
38_L45_K0.7640.76
103_K112_K0.7630.76
56_R64_E0.7620.76
162_K187_E0.7620.76
440_D445_V0.7620.76
477_T484_A0.7610.76
44_K65_T0.7610.76
634_V674_K0.7600.76
106_N109_K0.7580.76
246_E364_L0.7580.76
148_L181_I0.7570.76
56_R61_K0.7560.76
41_K53_G0.7550.76
322_I359_V0.7540.76
580_G583_K0.7540.76
103_K113_R0.7540.76
52_K64_E0.7520.75
521_V602_V0.7520.75
55_A66_N0.7510.75
343_T349_P0.7510.75
359_V368_G0.7480.75
108_N115_N0.7480.75
622_V625_Q0.7480.75
438_V444_R0.7460.75
38_L53_G0.7450.75
350_E375_M0.7440.75
152_L188_Y0.7440.75
39_E54_G0.7430.74
51_K58_K0.7430.74
103_K106_N0.7430.74
129_P134_P0.7430.74
280_T566_A0.7410.74
631_T701_E0.7400.74
101_K104_K0.7400.74
139_F181_I0.7400.74
38_L47_D0.7390.74
182_E192_T0.7390.74
223_T320_P0.7380.74
249_A597_R0.7370.74
125_K128_K0.7360.74
134_P190_V0.7360.74
210_D215_L0.7350.74
625_Q646_T0.7350.74
42_A61_K0.7350.74
161_K165_L0.7350.74
440_D452_T0.7340.74
105_N117_N0.7330.73
132_E135_E0.7330.73
40_E47_D0.7320.73
561_I582_A0.7320.73
203_L206_Y0.7300.73
675_R680_V0.7300.73
539_I543_G0.7300.73
361_L364_L0.7300.73
162_K184_I0.7270.73
571_V593_I0.7270.73
618_Y714_E0.7270.73
391_R418_T0.7260.73
57_A63_A0.7250.73
598_I606_I0.7250.73
210_D213_E0.7210.72
421_V444_R0.7210.72
334_N337_R0.7200.72
432_G459_L0.7190.72
579_D582_A0.7180.72
41_K52_K0.7180.72
504_D508_Q0.7180.72
47_D65_T0.7170.72
43_I65_T0.7150.72
315_K345_Y0.7140.71
201_T205_K0.7140.71
104_K109_K0.7140.71
104_K110_K0.7130.71
313_H317_A0.7130.71
635_S639_T0.7130.71
140_S151_E0.7130.71
367_K371_E0.7120.71
39_E52_K0.7120.71
631_T699_I0.7120.71
128_K132_E0.7120.71
46_L54_G0.7110.71
424_P482_G0.7110.71
47_D53_G0.7100.71
579_D584_S0.7100.71
111_N114_N0.7090.71
654_S709_V0.7080.71
154_K159_L0.7080.71
336_D352_W0.7050.71
42_A54_G0.7050.71
46_L53_G0.7040.70
45_K52_K0.7030.70
46_L65_T0.7030.70
345_Y356_T0.7030.70
108_N113_R0.6990.70
431_F460_N0.6990.70
187_E190_V0.6990.70
116_N119_K0.6990.70
115_N120_N0.6980.70
501_S504_D0.6970.70
178_K182_E0.6960.70
244_V247_G0.6940.69
238_S241_K0.6900.69
529_A533_T0.6890.69
623_I655_G0.6880.69
632_F668_G0.6870.69
544_V613_M0.6870.69
356_T375_M0.6860.68
112_K118_N0.6850.68
112_K115_N0.6840.68
308_V311_I0.6830.68
57_A64_E0.6830.68
143_L147_A0.6830.68
316_A518_N0.6830.68
42_A53_G0.6820.68
51_K62_P0.6810.68
340_Q343_T0.6810.68
292_I380_S0.6810.68
609_A612_G0.6800.68
118_N121_Q0.6790.68
217_I384_E0.6770.67
40_E55_A0.6770.67
41_K55_A0.6770.67
57_A65_T0.6750.67
103_K107_N0.6750.67
594_R605_E0.6730.67
56_R63_A0.6730.67
108_N120_N0.6730.67
102_N105_N0.6730.67
311_I342_L0.6730.67
499_K565_S0.6720.67
185_A190_V0.6720.67
299_A328_I0.6720.67
122_H126_P0.6720.67
297_V342_L0.6720.67
109_K116_N0.6710.67
105_N113_R0.6710.67
144_T176_L0.6710.67
186_S189_G0.6710.67
54_G61_K0.6700.67
652_R679_D0.6700.67
176_L590_N0.6700.67
42_A57_A0.6700.67
55_A65_T0.6700.67
49_K65_T0.6690.67
425_I434_V0.6650.66
111_N117_N0.6650.66
255_H411_T0.6650.66
103_K109_K0.6640.66
483_E486_A0.6640.66
106_N111_N0.6630.66
118_N125_K0.6630.66
269_T452_T0.6630.66
467_D477_T0.6630.66
479_R483_E0.6620.66
124_Q130_K0.6620.66
148_L159_L0.6600.65
119_K126_P0.6590.65
45_K50_Y0.6590.65
504_D509_I0.6570.65
576_V712_E0.6560.65
259_Y269_T0.6560.65
607_E618_Y0.6560.65
54_G65_T0.6550.65
103_K110_K0.6550.65
109_K118_N0.6530.65
53_G63_A0.6510.64
219_P452_T0.6510.64
38_L55_A0.6510.64
208_E421_V0.6500.64
110_K117_N0.6500.64
528_S598_I0.6500.64
673_L679_D0.6500.64
221_V415_Q0.6490.64
520_I552_G0.6490.64
339_M343_T0.6480.64
348_V358_F0.6470.64
163_L168_V0.6470.64
375_M379_V0.6470.64
467_D691_I0.6450.64
627_E704_I0.6430.63
289_V398_I0.6420.63
160_I172_I0.6410.63
108_N114_N0.6410.63
304_M338_V0.6410.63
63_A66_N0.6400.63
160_I173_N0.6400.63
52_K59_S0.6400.63
109_K121_Q0.6390.63
323_V347_L0.6390.63
113_R119_K0.6380.63
145_V159_L0.6380.63
102_N110_K0.6380.63
42_A65_T0.6370.63
38_L59_S0.6370.63
54_G57_A0.6360.63
572_I606_I0.6350.62
110_K120_N0.6340.62
148_L185_A0.6330.62
120_N125_K0.6330.62
423_D471_V0.6330.62
212_E215_L0.6330.62
140_S143_L0.6320.62
631_T692_T0.6310.62
219_P267_K0.6310.62
121_Q126_P0.6310.62
184_I188_Y0.6300.62
38_L50_Y0.6280.62
434_V456_I0.6280.62
59_S65_T0.6260.61
106_N114_N0.6260.61
144_T148_L0.6250.61
432_G471_V0.6230.61
107_N117_N0.6220.61
155_E158_E0.6210.61
392_Q471_V0.6210.61
40_E53_G0.6210.61
181_I184_I0.6190.61
42_A62_P0.6190.61
55_A60_Q0.6180.60
202_E206_Y0.6170.60
534_A538_K0.6170.60
474_D588_A0.6170.60
107_N114_N0.6160.60
108_N121_Q0.6160.60
155_E379_V0.6150.60
146_G149_A0.6150.60
60_Q66_N0.6140.60
608_A714_E0.6140.60
312_N552_G0.6130.60
516_D545_K0.6130.60
429_N489_Q0.6120.60
58_K64_E0.6120.60
41_K46_L0.6110.60
400_A526_Q0.6110.60
38_L56_R0.6090.59
235_L361_L0.6090.59
182_E194_E0.6080.59
312_N345_Y0.6080.59
48_A53_G0.6080.59
406_R409_V0.6080.59
54_G60_Q0.6070.59
555_A577_R0.6070.59
60_Q63_A0.6070.59
550_H560_D0.6060.59
105_N112_K0.6050.59
573_G578_P0.6050.59
164_M171_T0.6050.59
183_L191_E0.6050.59
242_T441_I0.6050.59
401_E411_T0.6050.59
40_E46_L0.6040.59
336_D340_Q0.6030.59
102_N106_N0.6030.59
150_E153_G0.6020.58
646_T685_Q0.6010.58
122_H130_K0.6010.58
49_K56_R0.6000.58
50_Y58_K0.6000.58
103_K111_N0.6000.58
135_E152_L0.6000.58
637_I674_K0.5990.58
168_V184_I0.5980.58
109_K120_N0.5980.58
610_M614_L0.5970.58
43_I52_K0.5960.58
164_M170_A0.5960.58
53_G65_T0.5950.58
44_K56_R0.5950.58
295_L342_L0.5940.57
492_E495_S0.5930.57
103_K108_N0.5930.57
406_R457_T0.5930.57
499_K568_N0.5920.57
99_F104_K0.5920.57
106_N120_N0.5910.57
541_V607_E0.5900.57
47_D52_K0.5900.57
539_I611_K0.5900.57
472_F477_T0.5880.57
626_V691_I0.5870.56
149_A152_L0.5870.56
464_Q467_D0.5850.56
154_K190_V0.5850.56
145_V170_A0.5840.56
643_G683_V0.5840.56
634_V640_I0.5830.56
313_H563_L0.5830.56
116_N124_Q0.5820.56
293_T379_V0.5820.56
521_V548_I0.5820.56
55_A62_P0.5810.56
610_M613_M0.5810.56
109_K119_K0.5800.56
127_V134_P0.5800.56
640_I692_T0.5800.56
562_I585_T0.5790.55
644_Y686_G0.5790.55
40_E56_R0.5770.55
53_G59_S0.5760.55
405_G409_V0.5750.55
377_L380_S0.5750.55
680_V692_T0.5750.55
129_P133_L0.5750.55
51_K63_A0.5730.55
224_I242_T0.5730.55
104_K108_N0.5730.55
62_P98_Q0.5720.55
99_F103_K0.5710.54
48_A60_Q0.5710.54
312_N316_A0.5700.54
540_E697_N0.5700.54
99_F102_N0.5680.54
339_M371_E0.5680.54
53_G60_Q0.5670.54
268_I376_I0.5670.54
115_N121_Q0.5660.54
100_N108_N0.5660.54
639_T693_I0.5660.54
224_I259_Y0.5660.54
671_D692_T0.5650.54
120_N126_P0.5650.54
315_K355_E0.5650.54
438_V457_T0.5640.54
107_N115_N0.5640.54
104_K113_R0.5640.54
477_T480_S0.5630.53
661_D664_V0.5630.53
580_G584_S0.5610.53
573_G576_V0.5600.53
224_I360_P0.5590.53
585_T588_A0.5590.53
145_V149_A0.5580.53
508_Q568_N0.5580.53
114_N117_N0.5580.53
497_K501_S0.5560.53
115_N119_K0.5560.53
216_E386_K0.5560.53
637_I656_L0.5550.52
38_L61_K0.5550.52
41_K65_T0.5550.52
50_Y65_T0.5540.52
630_Q635_S0.5530.52
644_Y685_Q0.5530.52
271_L529_A0.5530.52
474_D679_D0.5530.52
223_T289_V0.5520.52
644_Y675_R0.5520.52
47_D59_S0.5510.52
43_I56_R0.5510.52
519_L536_L0.5510.52
213_E388_N0.5500.52
673_L691_I0.5500.52
45_K57_A0.5470.51
107_N112_K0.5470.51
126_P133_L0.5470.51
44_K55_A0.5460.51
45_K62_P0.5450.51
52_K57_A0.5450.51
400_A549_I0.5450.51
183_L186_S0.5440.51
265_G374_E0.5430.51
49_K64_E0.5420.51
39_E48_A0.5410.51
675_R686_G0.5410.51
108_N116_N0.5410.51
361_L368_G0.5410.51
140_S181_I0.5410.51
109_K117_N0.5410.51
45_K56_R0.5400.50
100_N104_K0.5400.50
455_E610_M0.5400.50
488_K498_A0.5390.50
477_T481_V0.5390.50
109_K115_N0.5390.50
127_V131_K0.5390.50
107_N116_N0.5390.50
421_V438_V0.5390.50
360_P366_G0.5380.50
398_I533_T0.5380.50
324_A361_L0.5370.50
129_P136_K0.5370.50
113_R118_N0.5360.50
51_K56_R0.5360.50
38_L54_G0.5350.50
110_K118_N0.5350.50
346_G349_P0.5340.50
39_E44_K0.5340.50
154_K158_E0.5330.50
55_A61_K0.5330.50
114_N122_H0.5330.50
42_A58_K0.5320.49
157_S160_I0.5320.49
271_L525_V0.5320.49
352_W356_T0.5290.49
157_S161_K0.5280.49
111_N119_K0.5280.49
54_G66_N0.5280.49
643_G673_L0.5280.49
596_H601_K0.5270.49
127_V130_K0.5270.49
158_E162_K0.5260.49
251_G301_D0.5260.49
340_Q346_G0.5250.49
201_T206_Y0.5250.49
124_Q127_V0.5240.48
176_L247_G0.5230.48
101_K105_N0.5220.48
387_A450_P0.5210.48
116_N122_H0.5210.48
255_H271_L0.5210.48
238_S242_T0.5210.48
335_P338_V0.5200.48
575_N664_V0.5200.48
132_E136_K0.5190.48
521_V535_A0.5190.48
185_A189_G0.5190.48
49_K62_P0.5180.48
586_A592_D0.5180.48
211_N215_L0.5180.48
400_A467_D0.5180.48
434_V459_L0.5170.47
111_N120_N0.5170.47
215_L386_K0.5160.47
550_H559_S0.5150.47
49_K59_S0.5140.47
112_K125_K0.5130.47
52_K61_K0.5130.47
130_K133_L0.5130.47
426_V478_A0.5120.47
48_A59_S0.5110.47
340_Q352_W0.5110.47
347_L358_F0.5110.47
212_E388_N0.5100.47
219_P260_Q0.5090.46
44_K59_S0.5090.46
643_G650_I0.5090.46
48_A58_K0.5090.46
448_A453_P0.5080.46
146_G151_E0.5080.46
45_K60_Q0.5080.46
489_Q495_S0.5080.46
181_I185_A0.5080.46
594_R609_A0.5070.46
345_Y349_P0.5070.46
148_L184_I0.5060.46
38_L57_A0.5060.46
203_L470_L0.5060.46
340_Q344_E0.5060.46
197_V200_E0.5060.46
313_H316_A0.5050.46
45_K54_G0.5040.46
626_V692_T0.5040.46
50_Y66_N0.5020.46
645_V650_I0.5010.45
41_K56_R0.5010.45
48_A65_T0.5010.45
38_L44_K0.5010.45
500_L505_L0.5000.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1zo1I 1 0.6997 100 0.416 Contact Map
3j4jA 1 0.7905 100 0.422 Contact Map
3izyP 1 0.6899 100 0.426 Contact Map
3wbiA 1 0.6494 100 0.477 Contact Map
4n3nA 2 0.6606 100 0.486 Contact Map
4upyB 1 0.7053 100 0.49 Contact Map
1g7sA 1 0.6494 100 0.495 Contact Map
4kjzA 1 0.655 100 0.551 Contact Map
4n3sA 1 0.5182 100 0.591 Contact Map
4b43A 1 0.4791 100 0.732 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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