KINA - BACSU - GREMLIN Contacts

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KINA - Sporulation kinase A

UniProt:	P16497	Sequences: MEQDTQHVKPLQTKTDIHAVLASNGRIIYISANSKLHLGYLQGEMIGSFLKTFLHEEDQFLVESYFYNEHHLMPCTFRFIKKDHTIVWVEAAVEIVTTRAERTEREIILKMKVLEEETGHQSLNCEKHEIEPASPESTTYITDDYERLVENLPSPLCISVKGKIVYVNSAMLSMLGAKSKDAIIGKSSYEFIEEEYHDIVKNRIIRMQKGMEVGMIEQTWKRLDGTPVHLEVKASPTVYKNQQAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHNGKWVFMNESGISLFEAATYEDLIGKNIYDQLHPCDHEDVKERIQNIAEQKTESEIVKQSWFTFQNRVIYTEMVCIPTTFFGEAAVQVILRDISERKQTEELMLKSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQLMKPTMEGNEHYFDIVFSELSRIELILSELLMLAKPQQNAVKEYLNLKKLIGEVSALLETQANLNGIFIRTSYEKDSIYINGDQNQLKQVFINLIKNAVESMPDGGTVDIIITEDEHSVHVTVKDEGEGIPEKVLNRIGEPFLTTKEKGTGLGLMVTFNIIENHQGVIHVDSHPEKGTAFKISFPKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	606 (471)
Sequences:	7925 (6930)
Seq/√Len:	319.3

ECOLI - ARCB RCSD RCSC EVGS ATOS TORS BARA DPIB
BACSU - KINA KINE YYCG PHOR KINC RESE CITS DCTS
HALSA - Q9HQ16 O51970 Q9HQG5 Q9HRE4 Q9HR10 Q9HRG1 BAT Q9HNM2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
278_D	375_R	4.325	1.00
418_L	435_V	4.275	1.00
154_S	250_I	3.967	1.00
391_E	394_S	3.331	1.00
588_H	600_K	3.325	1.00
592_H	595_K	2.979	1.00
281_A	372_V	2.946	1.00
266_R	270_Q	2.811	1.00
554_L	589_V	2.762	1.00
543_K	598_A	2.746	1.00
550_P	553_V	2.746	1.00
577_F	581_E	2.668	1.00
464_L	501_G	2.607	1.00
589_V	599_F	2.578	1.00
294_S	297_S	2.576	1.00
342_K	381_K	2.562	1.00
217_E	256_K	2.503	1.00
576_T	587_I	2.472	1.00
521_M	545_E	2.456	1.00
142_T	146_E	2.439	1.00
255_R	259_Q	2.429	1.00
239_Y	243_Q	2.348	1.00
509_V	580_I	2.330	1.00
320_D	344_S	2.323	1.00
347_T	351_R	2.307	1.00
540_V	601_I	2.306	1.00
415_K	439_L	2.296	1.00
177_A	223_L	2.289	1.00
462_E	503_Q	2.285	1.00
155_P	249_L	2.275	1.00
539_H	600_K	2.272	1.00
149_V	166_Y	2.261	1.00
549_I	553_V	2.238	1.00
222_R	226_T	2.236	1.00
256_K	259_Q	2.235	1.00
501_G	583_H	2.232	1.00
381_K	384_E	2.220	1.00
380_R	384_E	2.216	1.00
347_T	353_I	2.193	1.00
279_T	298_L	2.193	1.00
279_T	374_L	2.182	1.00
170_A	173_S	2.175	1.00
364_F	367_E	2.166	1.00
273_I	290_F	2.151	1.00
356_E	380_R	2.114	1.00
361_P	368_A	2.113	1.00
155_P	174_M	2.107	1.00
130_I	134_S	2.091	1.00
231_E	250_I	2.084	1.00
422_K	433_D	2.053	1.00
169_S	173_S	2.048	1.00
463_Y	500_N	2.044	1.00
491_S	530_I	1.992	1.00
152_L	156_L	1.978	1.00
530_I	541_T	1.959	1.00
146_E	150_E	1.959	1.00
541_T	598_A	1.950	1.00
356_E	375_R	1.946	1.00
302_A	348_F	1.934	1.00
539_H	602_S	1.933	1.00
422_K	436_F	1.924	1.00
530_I	543_K	1.903	1.00
270_Q	274_Q	1.879	1.00
215_M	231_E	1.869	1.00
537_S	602_S	1.864	1.00
532_T	539_H	1.855	1.00
344_S	352_V	1.834	1.00
465_N	468_K	1.813	1.00
520_S	563_T	1.805	1.00
282_V	369_A	1.790	1.00
219_T	229_H	1.743	1.00
159_S	163_K	1.740	1.00
239_Y	242_Q	1.724	1.00
379_E	382_Q	1.711	1.00
489_R	526_T	1.696	1.00
528_D	543_K	1.694	1.00
222_R	228_V	1.691	1.00
544_D	548_G	1.682	1.00
550_P	593_P	1.680	1.00
293_E	297_S	1.672	1.00
196_Y	219_T	1.669	1.00
357_M	374_L	1.666	1.00
384_E	388_L	1.656	1.00
509_V	576_T	1.640	1.00
580_I	601_I	1.637	1.00
317_H	320_D	1.634	1.00
491_S	528_D	1.629	1.00
182_A	223_L	1.615	1.00
467_K	531_I	1.612	1.00
344_S	354_Y	1.612	1.00
343_Q	357_M	1.608	1.00
167_V	171_M	1.602	1.00
284_H	287_K	1.593	1.00
265_S	268_R	1.592	1.00
178_K	182_A	1.585	1.00
281_A	288_W	1.585	1.00
276_S	280_I	1.584	1.00
306_D	348_F	1.580	1.00
580_I	585_G	1.579	1.00
363_T	368_A	1.578	1.00
509_V	579_I	1.573	1.00
186_K	190_E	1.555	1.00
489_R	528_D	1.552	1.00
541_T	600_K	1.546	1.00
130_I	133_A	1.542	1.00
532_T	541_T	1.538	1.00
421_M	432_F	1.535	1.00
346_F	352_V	1.524	1.00
172_L	180_K	1.521	1.00
521_M	527_V	1.520	1.00
551_E	554_L	1.515	1.00
167_V	172_L	1.514	1.00
219_T	227_P	1.510	1.00
472_E	507_K	1.504	1.00
274_Q	293_E	1.489	1.00
510_F	540_V	1.485	1.00
581_E	586_V	1.463	1.00
413_A	438_E	1.462	1.00
169_S	172_L	1.461	1.00
229_H	256_K	1.460	1.00
150_E	169_S	1.458	1.00
591_S	597_T	1.438	1.00
281_A	295_G	1.437	1.00
157_C	247_L	1.432	1.00
521_M	525_G	1.420	1.00
141_I	144_D	1.417	1.00
269_Y	273_I	1.415	1.00
193_E	196_Y	1.409	1.00
586_V	602_S	1.402	1.00
558_G	587_I	1.393	1.00
167_V	183_I	1.390	1.00
579_I	583_H	1.381	1.00
417_F	431_Y	1.377	1.00
232_V	249_L	1.367	1.00
422_K	429_E	1.358	1.00
131_E	134_S	1.345	1.00
505_Q	508_Q	1.344	1.00
487_F	526_T	1.343	1.00
175_L	220_W	1.339	1.00
590_D	598_A	1.335	1.00
310_K	314_D	1.334	1.00
231_E	255_R	1.327	1.00
525_G	545_E	1.327	1.00
549_I	557_I	1.324	1.00
386_L	389_K	1.323	1.00
282_V	371_Q	1.309	1.00
218_Q	232_V	1.307	1.00
553_V	556_R	1.297	1.00
382_Q	386_L	1.296	1.00
385_E	388_L	1.287	1.00
291_M	296_I	1.278	1.00
492_Y	531_I	1.277	1.00
467_K	492_Y	1.271	1.00
260_T	264_K	1.269	1.00
221_K	227_P	1.262	1.00
477_L	514_I	1.260	1.00
501_G	506_L	1.249	1.00
295_G	299_F	1.246	1.00
559_E	562_L	1.244	1.00
329_Q	333_E	1.238	1.00
419_Q	436_F	1.237	1.00
236_P	244_A	1.233	1.00
317_H	344_S	1.232	1.00
590_D	600_K	1.232	1.00
481_A	518_V	1.230	1.00
269_Y	272_L	1.225	1.00
145_Y	149_V	1.218	1.00
497_I	533_E	1.215	1.00
477_L	511_I	1.214	1.00
259_Q	263_Q	1.212	1.00
138_T	141_I	1.208	1.00
591_S	594_E	1.200	1.00
421_M	428_N	1.197	1.00
303_T	306_D	1.194	1.00
260_T	263_Q	1.188	1.00
296_I	304_Y	1.181	1.00
556_R	562_L	1.180	1.00
171_M	175_L	1.176	1.00
383_T	387_M	1.174	1.00
177_A	182_A	1.174	1.00
169_S	180_K	1.171	1.00
424_T	428_N	1.162	1.00
443_E	447_S	1.160	1.00
502_D	505_Q	1.159	1.00
317_H	352_V	1.148	1.00
508_Q	579_I	1.145	1.00
234_A	245_E	1.139	1.00
425_M	428_N	1.131	1.00
403_I	449_L	1.131	1.00
283_I	328_I	1.128	1.00
418_L	422_K	1.125	1.00
206_R	210_G	1.124	1.00
291_M	295_G	1.121	1.00
268_R	282_V	1.118	1.00
401_A	406_E	1.101	1.00
330_N	335_K	1.097	1.00
187_S	190_E	1.090	1.00
417_F	434_I	1.087	1.00
145_Y	148_L	1.085	1.00
354_Y	378_S	1.084	1.00
142_T	145_Y	1.082	1.00
551_E	592_H	1.081	1.00
265_S	269_Y	1.079	1.00
254_S	257_K	1.074	1.00
342_K	356_E	1.070	1.00
193_E	219_T	1.067	1.00
252_I	256_K	1.065	1.00
406_E	409_N	1.061	1.00
478_E	482_N	1.060	1.00
472_E	503_Q	1.059	1.00
299_F	345_W	1.059	1.00
591_S	595_K	1.058	1.00
382_Q	385_E	1.057	1.00
526_T	545_E	1.055	1.00
262_L	265_S	1.045	1.00
157_C	164_I	1.040	1.00
261_I	264_K	1.039	1.00
282_V	289_V	1.038	1.00
385_E	389_K	1.036	1.00
480_Q	483_L	1.033	1.00
283_I	359_C	1.032	1.00
193_E	227_P	1.030	1.00
509_V	601_I	1.018	1.00
138_T	142_T	1.015	1.00
387_M	391_E	1.013	1.00
229_H	253_S	1.010	1.00
158_I	188_S	1.008	1.00
215_M	233_K	1.008	1.00
414_I	439_L	1.007	1.00
165_V	244_A	1.005	1.00
180_K	184_I	1.005	1.00
519_E	563_T	1.003	1.00
406_E	410_P	1.002	1.00
166_Y	180_K	1.002	1.00
292_N	295_G	1.001	1.00
155_P	168_N	1.000	1.00
280_I	292_N	0.999	1.00
139_T	142_T	0.999	1.00
293_E	296_I	0.998	1.00
172_L	178_K	0.998	1.00
513_L	542_V	0.993	1.00
158_I	247_L	0.987	1.00
481_A	527_V	0.985	1.00
477_L	518_V	0.981	1.00
266_R	269_Y	0.978	1.00
514_I	529_I	0.976	1.00
408_R	443_E	0.974	1.00
418_L	436_F	0.973	1.00
414_I	435_V	0.970	1.00
283_I	312_I	0.969	1.00
168_N	171_M	0.965	1.00
155_P	171_M	0.965	1.00
267_E	271_L	0.956	1.00
361_P	369_A	0.955	1.00
553_V	564_T	0.954	1.00
204_I	234_A	0.953	1.00
434_I	438_E	0.952	1.00
289_V	369_A	0.949	1.00
549_I	555_N	0.946	1.00
359_C	370_V	0.945	1.00
554_L	591_S	0.944	1.00
558_G	599_F	0.941	1.00
416_G	420_L	0.941	1.00
272_L	371_Q	0.939	1.00
531_I	540_V	0.939	1.00
263_Q	266_R	0.939	1.00
396_A	400_A	0.937	1.00
273_I	292_N	0.936	1.00
279_T	295_G	0.934	1.00
255_R	258_F	0.933	1.00
510_F	514_I	0.931	1.00
580_I	587_I	0.931	1.00
330_N	334_Q	0.929	1.00
283_I	372_V	0.928	1.00
407_I	445_I	0.928	1.00
537_S	586_V	0.925	1.00
229_H	252_I	0.914	1.00
406_E	508_Q	0.913	1.00
505_Q	579_I	0.912	1.00
278_D	294_S	0.910	1.00
149_V	156_L	0.909	1.00
514_I	527_V	0.908	1.00
296_I	303_T	0.907	1.00
311_N	314_D	0.907	1.00
413_A	417_F	0.906	1.00
201_K	205_I	0.900	1.00
178_K	181_D	0.896	1.00
463_Y	498_Y	0.895	1.00
158_I	234_A	0.895	1.00
558_G	589_V	0.892	1.00
157_C	246_L	0.889	1.00
163_K	187_S	0.888	1.00
272_L	276_S	0.882	1.00
273_I	280_I	0.881	1.00
557_I	599_F	0.880	1.00
362_T	369_A	0.879	1.00
205_I	209_K	0.879	1.00
207_M	236_P	0.878	1.00
291_M	307_L	0.876	1.00
175_L	249_L	0.873	1.00
326_E	330_N	0.872	1.00
415_K	440_S	0.872	1.00
430_H	434_I	0.870	1.00
143_D	147_R	0.866	1.00
354_Y	377_I	0.863	1.00
466_L	538_V	0.862	1.00
202_N	206_R	0.859	1.00
557_I	589_V	0.857	1.00
331_I	370_V	0.856	1.00
220_W	228_V	0.856	1.00
359_C	372_V	0.856	1.00
137_S	140_Y	0.855	1.00
283_I	286_G	0.854	1.00
417_F	435_V	0.853	1.00
464_L	469_L	0.849	1.00
134_S	139_T	0.846	1.00
354_Y	381_K	0.846	1.00
588_H	602_S	0.845	1.00
296_I	307_L	0.844	1.00
448_E	505_Q	0.844	1.00
549_I	554_L	0.843	1.00
436_F	440_S	0.842	1.00
353_I	376_D	0.842	1.00
235_S	246_L	0.838	1.00
293_E	304_Y	0.835	1.00
486_I	490_T	0.835	1.00
539_H	588_H	0.834	1.00
412_T	416_G	0.834	1.00
417_F	438_E	0.833	1.00
292_N	376_D	0.833	1.00
230_L	249_L	0.832	1.00
263_Q	267_E	0.832	1.00
283_I	288_W	0.827	1.00
167_V	175_L	0.822	1.00
435_V	439_L	0.821	1.00
390_S	394_S	0.817	1.00
470_I	510_F	0.816	1.00
157_C	244_A	0.816	1.00
149_V	168_N	0.809	1.00
282_V	292_N	0.809	1.00
194_E	197_H	0.807	1.00
151_N	246_L	0.807	1.00
237_T	244_A	0.806	1.00
413_A	434_I	0.806	1.00
451_M	505_Q	0.804	1.00
156_L	168_N	0.804	1.00
513_L	601_I	0.803	1.00
521_M	524_G	0.802	1.00
164_I	168_N	0.800	1.00
156_L	246_L	0.792	1.00
287_K	311_N	0.790	1.00
465_N	498_Y	0.789	1.00
359_C	374_L	0.789	1.00
513_L	587_I	0.788	1.00
158_I	162_G	0.784	1.00
290_F	304_Y	0.784	1.00
526_T	543_K	0.783	1.00
588_H	601_I	0.782	1.00
324_V	343_Q	0.781	1.00
239_Y	244_A	0.779	1.00
560_P	578_N	0.779	1.00
228_V	251_D	0.774	1.00
281_A	374_L	0.771	1.00
345_W	353_I	0.771	1.00
168_N	251_D	0.770	1.00
418_L	439_L	0.770	1.00
158_I	204_I	0.770	1.00
471_G	490_T	0.769	1.00
411_L	446_L	0.767	0.99
360_I	371_Q	0.765	0.99
199_I	202_N	0.765	0.99
517_A	527_V	0.765	0.99
362_T	371_Q	0.765	0.99
282_V	290_F	0.763	0.99
493_E	532_T	0.761	0.99
258_F	261_I	0.757	0.99
431_Y	435_V	0.756	0.99
304_Y	308_I	0.755	0.99
148_L	246_L	0.755	0.99
421_M	435_V	0.751	0.99
175_L	228_V	0.749	0.99
192_I	200_V	0.748	0.99
470_I	529_I	0.748	0.99
157_C	168_N	0.744	0.99
290_F	293_E	0.742	0.99
507_K	511_I	0.741	0.99
316_L	343_Q	0.739	0.99
454_K	569_T	0.739	0.99
406_E	445_I	0.738	0.99
389_K	392_K	0.738	0.99
325_K	329_Q	0.738	0.99
192_I	196_Y	0.734	0.99
256_K	260_T	0.734	0.99
464_L	506_L	0.732	0.99
298_L	355_T	0.732	0.99
377_I	381_K	0.732	0.99
276_S	373_I	0.731	0.99
238_V	242_Q	0.731	0.99
154_S	170_A	0.729	0.99
460_V	505_Q	0.728	0.99
322_E	326_E	0.728	0.99
384_E	387_M	0.727	0.99
433_D	437_S	0.725	0.99
154_S	248_L	0.724	0.99
302_A	306_D	0.724	0.99
203_R	207_M	0.724	0.99
515_K	519_E	0.723	0.99
200_V	207_M	0.721	0.99
407_I	442_I	0.721	0.99
283_I	370_V	0.720	0.99
363_T	369_A	0.719	0.99
473_V	514_I	0.719	0.99
144_D	166_Y	0.719	0.99
556_R	559_E	0.718	0.99
418_L	432_F	0.717	0.99
155_P	170_A	0.717	0.99
549_I	597_T	0.717	0.99
261_I	265_S	0.716	0.99
141_I	146_E	0.715	0.99
257_K	261_I	0.714	0.99
469_L	473_V	0.714	0.99
218_Q	234_A	0.714	0.99
406_E	438_E	0.714	0.99
364_F	369_A	0.713	0.99
313_Y	321_H	0.712	0.99
284_H	289_V	0.712	0.99
217_E	231_E	0.709	0.99
549_I	589_V	0.708	0.99
513_L	599_F	0.708	0.99
408_R	442_I	0.706	0.99
207_M	245_E	0.705	0.99
383_T	386_L	0.704	0.99
167_V	180_K	0.701	0.99
476_L	511_I	0.701	0.99
279_T	299_F	0.701	0.99
450_L	569_T	0.701	0.99
268_R	290_F	0.701	0.99
328_I	359_C	0.699	0.99
404_A	409_N	0.697	0.99
549_I	573_L	0.697	0.99
571_L	575_V	0.697	0.99
318_P	321_H	0.697	0.99
148_L	152_L	0.696	0.99
409_N	416_G	0.695	0.99
364_F	368_A	0.692	0.99
148_L	157_C	0.692	0.99
296_I	302_A	0.692	0.99
420_L	431_Y	0.688	0.99
403_I	438_E	0.688	0.99
355_T	374_L	0.688	0.99
198_D	202_N	0.688	0.99
147_R	246_L	0.686	0.99
467_K	471_G	0.686	0.99
312_I	328_I	0.683	0.99
232_V	247_L	0.682	0.99
192_I	197_H	0.680	0.99
561_F	574_M	0.679	0.99
299_F	374_L	0.677	0.99
408_R	450_L	0.676	0.99
279_T	292_N	0.676	0.99
470_I	531_I	0.675	0.99
403_I	409_N	0.675	0.99
279_T	357_M	0.673	0.99
466_L	540_V	0.672	0.99
279_T	296_I	0.672	0.99
192_I	218_Q	0.672	0.99
334_Q	337_E	0.671	0.99
206_R	211_M	0.671	0.99
547_E	591_S	0.669	0.99
313_Y	325_K	0.667	0.99
272_L	282_V	0.666	0.99
563_T	567_K	0.663	0.99
272_L	277_I	0.661	0.99
331_I	361_P	0.659	0.98
509_V	583_H	0.659	0.98
528_D	545_E	0.657	0.98
281_A	359_C	0.656	0.98
264_K	268_R	0.654	0.98
220_W	230_L	0.654	0.98
519_E	565_K	0.653	0.98
284_H	369_A	0.653	0.98
438_E	441_R	0.651	0.98
278_D	373_I	0.651	0.98
217_E	255_R	0.651	0.98
407_I	410_P	0.650	0.98
234_A	247_L	0.650	0.98
399_L	404_A	0.650	0.98
148_L	153_P	0.647	0.98
448_E	508_Q	0.647	0.98
406_E	442_I	0.647	0.98
140_Y	144_D	0.646	0.98
468_K	472_E	0.645	0.98
415_K	443_E	0.643	0.98
139_T	143_D	0.641	0.98
402_G	409_N	0.641	0.98
450_L	453_A	0.641	0.98
473_V	511_I	0.640	0.98
529_I	540_V	0.639	0.98
189_Y	197_H	0.638	0.98
172_L	175_L	0.638	0.98
207_M	210_G	0.637	0.98
407_I	411_L	0.636	0.98
406_E	561_F	0.635	0.98
134_S	138_T	0.635	0.98
426_E	429_E	0.635	0.98
547_E	597_T	0.635	0.98
155_P	232_V	0.634	0.98
282_V	362_T	0.634	0.98
380_R	383_T	0.634	0.98
473_V	477_L	0.633	0.98
560_P	574_M	0.633	0.98
470_I	490_T	0.632	0.98
450_L	454_K	0.631	0.98
279_T	355_T	0.631	0.98
589_V	597_T	0.630	0.98
387_M	390_S	0.629	0.98
322_E	325_K	0.628	0.98
281_A	357_M	0.627	0.98
279_T	294_S	0.627	0.98
409_N	443_E	0.626	0.98
280_I	290_F	0.626	0.98
143_D	146_E	0.626	0.98
136_E	140_Y	0.624	0.98
486_I	518_V	0.624	0.98
163_K	184_I	0.623	0.98
397_G	452_L	0.622	0.98
258_F	262_L	0.621	0.98
188_S	234_A	0.621	0.98
269_Y	371_Q	0.620	0.98
164_I	167_V	0.619	0.98
300_E	347_T	0.617	0.98
419_Q	422_K	0.617	0.98
414_I	418_L	0.616	0.98
534_D	539_H	0.614	0.98
451_M	455_P	0.614	0.98
177_A	191_F	0.613	0.98
422_K	432_F	0.612	0.98
390_S	393_L	0.612	0.98
358_V	375_R	0.611	0.98
553_V	562_L	0.611	0.98
269_Y	290_F	0.611	0.98
286_G	292_N	0.610	0.97
298_L	353_I	0.609	0.97
352_V	378_S	0.607	0.97
312_I	374_L	0.606	0.97
378_S	382_Q	0.606	0.97
469_L	501_G	0.603	0.97
159_S	165_V	0.603	0.97
357_M	372_V	0.602	0.97
158_I	245_E	0.601	0.97
137_S	141_I	0.601	0.97
334_Q	338_S	0.601	0.97
510_F	542_V	0.600	0.97
506_L	583_H	0.600	0.97
295_G	374_L	0.599	0.97
415_K	418_L	0.599	0.97
411_L	417_F	0.598	0.97
406_E	576_T	0.597	0.97
152_L	155_P	0.596	0.97
200_V	203_R	0.595	0.97
484_N	521_M	0.595	0.97
505_Q	583_H	0.595	0.97
164_I	247_L	0.595	0.97
205_I	208_Q	0.594	0.97
324_V	327_R	0.594	0.97
323_D	326_E	0.593	0.97
200_V	218_Q	0.592	0.97
361_P	370_V	0.592	0.97
400_A	563_T	0.591	0.97
281_A	291_M	0.591	0.97
424_T	431_Y	0.591	0.97
300_E	349_Q	0.590	0.97
172_L	177_A	0.590	0.97
331_I	338_S	0.589	0.97
292_N	296_I	0.588	0.97
585_G	604_P	0.588	0.97
409_N	450_L	0.588	0.97
345_W	355_T	0.588	0.97
156_L	248_L	0.588	0.97
493_E	531_I	0.588	0.97
203_R	206_R	0.587	0.97
229_H	235_S	0.586	0.97
473_V	507_K	0.584	0.97
396_A	409_N	0.584	0.97
503_Q	507_K	0.583	0.97
409_N	413_A	0.583	0.97
338_S	341_V	0.581	0.97
171_M	249_L	0.577	0.96
274_Q	290_F	0.577	0.96
564_T	567_K	0.577	0.96
316_L	324_V	0.577	0.96
238_V	244_A	0.575	0.96
152_L	248_L	0.575	0.96
271_L	275_N	0.573	0.96
421_M	431_Y	0.573	0.96
505_Q	582_N	0.571	0.96
237_T	246_L	0.571	0.96
534_D	537_S	0.571	0.96
155_P	230_L	0.570	0.96
439_L	443_E	0.569	0.96
158_I	164_I	0.568	0.96
288_W	292_N	0.566	0.96
172_L	183_I	0.566	0.96
437_S	472_E	0.566	0.96
291_M	304_Y	0.566	0.96
484_N	518_V	0.566	0.96
519_E	567_K	0.566	0.96
330_N	336_T	0.565	0.96
343_Q	359_C	0.565	0.96
316_L	321_H	0.564	0.96
444_L	504_N	0.563	0.96
133_A	138_T	0.563	0.96
474_S	478_E	0.563	0.96
465_N	496_S	0.562	0.96
549_I	591_S	0.561	0.96
159_S	244_A	0.560	0.96
481_A	486_I	0.560	0.96
153_P	168_N	0.560	0.96
491_S	532_T	0.558	0.96
295_G	375_R	0.558	0.96
578_N	581_E	0.558	0.96
549_I	599_F	0.557	0.96
512_N	576_T	0.557	0.96
513_L	576_T	0.557	0.96
405_H	512_N	0.556	0.96
587_I	601_I	0.556	0.96
295_G	298_L	0.555	0.96
288_W	372_V	0.554	0.96
402_G	560_P	0.553	0.96
272_L	280_I	0.553	0.96
265_S	270_Q	0.552	0.96
342_K	380_R	0.552	0.96
550_P	564_T	0.550	0.95
134_S	137_S	0.549	0.95
469_L	507_K	0.549	0.95
287_K	309_G	0.549	0.95
401_A	409_N	0.549	0.95
278_D	371_Q	0.549	0.95
136_E	139_T	0.548	0.95
149_V	152_L	0.547	0.95
216_I	232_V	0.547	0.95
282_V	286_G	0.546	0.95
452_L	574_M	0.546	0.95
397_G	456_Q	0.545	0.95
277_I	360_I	0.543	0.95
477_L	515_K	0.542	0.95
290_F	354_Y	0.541	0.95
192_I	220_W	0.541	0.95
520_S	547_E	0.539	0.95
164_I	171_M	0.533	0.95
575_V	579_I	0.533	0.95
144_D	148_L	0.532	0.95
168_N	253_S	0.530	0.94
257_K	260_T	0.530	0.94
292_N	343_Q	0.530	0.94
509_V	540_V	0.529	0.94
415_K	436_F	0.528	0.94
408_R	447_S	0.528	0.94
164_I	185_G	0.527	0.94
171_M	247_L	0.526	0.94
496_S	531_I	0.526	0.94
275_N	358_V	0.525	0.94
163_K	185_G	0.523	0.94
277_I	375_R	0.522	0.94
228_V	234_A	0.522	0.94
172_L	176_G	0.521	0.94
153_P	246_L	0.521	0.94
562_L	565_K	0.521	0.94
275_N	282_V	0.520	0.94
174_M	228_V	0.520	0.94
236_P	245_E	0.520	0.94
240_K	243_Q	0.520	0.94
400_A	579_I	0.519	0.94
176_G	182_A	0.519	0.94
145_Y	166_Y	0.518	0.94
220_W	232_V	0.518	0.94
447_S	451_M	0.518	0.94
345_W	357_M	0.518	0.94
220_W	229_H	0.517	0.94
274_Q	292_N	0.517	0.94
401_A	407_I	0.516	0.94
195_E	227_P	0.516	0.94
141_I	145_Y	0.516	0.94
164_I	204_I	0.515	0.94
207_M	211_M	0.515	0.94
323_D	327_R	0.514	0.93
417_F	424_T	0.514	0.93
158_I	175_L	0.514	0.93
469_L	472_E	0.514	0.93
295_G	307_L	0.512	0.93
410_P	575_V	0.512	0.93
188_S	191_F	0.511	0.93
343_Q	374_L	0.509	0.93
345_W	374_L	0.508	0.93
521_M	563_T	0.506	0.93
218_Q	229_H	0.506	0.93
441_R	507_K	0.504	0.93
188_S	200_V	0.503	0.93
439_L	442_I	0.503	0.93
511_I	576_T	0.503	0.93
279_T	370_V	0.503	0.93
288_W	309_G	0.502	0.93
338_S	359_C	0.502	0.93
493_E	496_S	0.502	0.93
254_S	258_F	0.501	0.93
177_A	222_R	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4gczA	2	0.5759	100	0.479	Contact Map
3a0rA	2	0.5314	100	0.509	Contact Map
4i5sA	2	0.6287	100	0.536	Contact Map
4r3aA	1	0.505	100	0.583	Contact Map
4q20A	2	0.363	100	0.641	Contact Map
3d36A	2	0.3564	100	0.645	Contact Map
2c2aA	2	0.3746	100	0.647	Contact Map
4mpcA	2	0.4769	100	0.648	Contact Map
3jz3A	2	0.2574	100	0.649	Contact Map
2q8gA	2	0.4835	100	0.651	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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