GREMLIN Database
SUBE - Minor extracellular protease Epr
UniProt: P16396 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 645 (543)
Sequences: 265 (248)
Seq/√Len: 10.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
284_A292_A6.1941.00
182_A313_T5.9221.00
274_A281_A5.7251.00
175_H327_Q5.4381.00
335_M378_Y4.7421.00
132_T195_E4.5491.00
139_A222_S4.4751.00
260_A329_T4.3631.00
283_S304_S4.0350.99
246_A250_A4.0000.99
140_V180_I3.7510.98
122_Q377_Q3.6170.98
199_Y227_M3.5910.98
175_H312_S3.5850.98
223_I255_V3.3630.97
335_M376_I3.3180.97
178_G312_S3.2820.96
159_A221_W3.2500.96
138_I180_I3.2010.96
150_D182_A3.0300.94
40_K84_L3.0170.94
133_G193_A2.9600.93
179_I331_H2.9070.93
231_N273_P2.9030.93
174_T315_L2.6880.89
59_Y64_A2.6520.89
203_A234_L2.5710.87
39_Y65_V2.5240.86
158_S166_Y2.4940.85
158_S163_T2.4940.85
314_Y320_A2.4550.84
204_L261_S2.3960.83
339_L351_L2.3480.82
176_V234_L2.3360.81
223_I250_A2.3140.81
358_N381_Q2.3030.80
312_S327_Q2.2860.80
284_A294_F2.2710.79
121_I280_V2.2500.79
150_D313_T2.1960.77
322_G327_Q2.1810.76
296_T301_V2.1110.74
296_T371_F2.0320.71
38_V84_L1.9900.69
511_A515_I1.9760.69
234_L250_A1.9760.69
219_I222_S1.9550.68
137_K199_Y1.9300.67
301_V371_F1.9120.66
177_A203_A1.8980.66
219_I250_A1.8610.64
133_G296_T1.8170.62
204_L210_G1.8110.62
201_V225_N1.7990.61
137_K197_Q1.7940.61
219_I231_N1.7870.61
201_V283_S1.7710.60
498_K505_K1.7440.59
221_W371_F1.7420.59
148_H319_Y1.7350.58
259_A279_V1.7340.58
562_Q567_Q1.7310.58
566_N571_G1.7280.58
301_V367_R1.7150.57
140_V218_G1.7050.57
258_V329_T1.7020.57
172_H326_S1.6990.57
292_A308_T1.6980.57
141_I210_G1.6860.56
220_D253_Q1.6480.54
223_I230_V1.6470.54
260_A264_D1.6420.54
192_I228_D1.6410.54
553_S556_A1.6170.53
218_G283_S1.6130.53
556_A563_S1.6060.52
135_N193_A1.5970.52
234_L259_A1.5940.52
136_I229_I1.5870.51
363_G366_G1.5390.49
559_A562_Q1.5330.49
176_V231_N1.5220.48
284_A323_S1.5210.48
346_E350_Q1.5110.48
138_I337_A1.5070.48
227_M255_V1.4980.47
552_K558_A1.4950.47
183_K296_T1.4940.47
467_L471_T1.4910.47
458_D477_Q1.4810.46
175_H178_G1.4760.46
172_H330_P1.4750.46
175_H306_P1.4750.46
210_G331_H1.4680.46
555_D565_V1.4660.46
121_I331_H1.4620.45
303_F376_I1.4600.45
230_V250_A1.4510.45
361_D368_D1.4490.45
566_N572_K1.4480.45
465_N468_P1.4440.45
182_A349_V1.4240.44
302_E307_G1.4180.43
566_N577_L1.4170.43
219_I234_L1.4110.43
142_D173_G1.4100.43
360_V377_Q1.4090.43
471_T477_Q1.4060.43
262_G326_S1.4010.43
154_A197_Q1.3760.41
367_R373_Y1.3620.41
453_T456_T1.3560.41
176_V273_P1.3550.40
87_E334_A1.3450.40
558_A577_L1.3420.40
296_T300_E1.3380.40
298_G312_S1.3260.39
122_Q208_G1.3180.39
564_A571_G1.3150.39
223_I234_L1.3100.38
567_Q571_G1.3000.38
562_Q565_V1.2920.38
221_W296_T1.2910.38
284_A375_L1.2840.37
338_L378_Y1.2840.37
559_A563_S1.2830.37
562_Q571_G1.2790.37
215_L234_L1.2750.37
498_K504_K1.2700.37
159_A225_N1.2700.37
557_N566_N1.2690.37
133_G301_V1.2690.37
319_Y337_A1.2650.36
302_E312_S1.2640.36
496_V513_S1.2630.36
219_I246_A1.2590.36
571_G575_T1.2570.36
430_D443_D1.2560.36
260_A274_A1.2560.36
179_I296_T1.2550.36
272_Y281_A1.2540.36
485_R490_K1.2470.36
176_V203_A1.2440.36
569_Q573_D1.2420.35
292_A323_S1.2420.35
565_V572_K1.2400.35
146_S282_V1.2390.35
567_Q576_A1.2370.35
303_F307_G1.2370.35
146_S327_Q1.2310.35
275_A352_R1.2310.35
498_K501_K1.2290.35
172_H262_G1.2260.35
168_D171_G1.2160.34
552_K555_D1.2150.34
221_W297_T1.2140.34
221_W225_N1.2120.34
560_K566_N1.2050.34
567_Q577_L1.2040.34
150_D391_E1.2010.34
557_N564_A1.2000.34
484_K493_K1.1990.34
203_A232_M1.1960.33
145_I200_A1.1960.33
174_T208_G1.1930.33
236_T292_A1.1930.33
508_V515_I1.1890.33
77_L80_D1.1890.33
133_G235_G1.1880.33
59_Y66_A1.1880.33
536_S539_L1.1850.33
201_V373_Y1.1820.33
227_M250_A1.1810.33
158_S315_L1.1790.33
199_Y223_I1.1760.33
468_P483_V1.1760.33
133_G341_Q1.1690.32
558_A562_Q1.1680.32
172_H233_S1.1650.32
535_K546_V1.1640.32
337_A341_Q1.1630.32
151_L174_T1.1620.32
284_A308_T1.1610.32
283_S297_T1.1610.32
568_L572_K1.1590.32
259_A296_T1.1520.32
464_I467_L1.1510.32
142_D374_G1.1510.32
120_P179_I1.1500.32
510_S574_K1.1470.31
232_M259_A1.1470.31
259_A272_Y1.1460.31
250_A254_G1.1440.31
460_A464_I1.1430.31
145_I295_S1.1430.31
508_V518_L1.1420.31
301_V373_Y1.1390.31
282_V307_G1.1370.31
148_H312_S1.1330.31
561_A571_G1.1290.31
274_A370_Q1.1260.31
300_E371_F1.1240.31
551_K561_A1.1210.30
128_K335_M1.1210.30
557_N563_S1.1160.30
356_R373_Y1.1160.30
135_N228_D1.1140.30
568_L574_K1.1130.30
477_Q481_D1.1120.30
551_K571_G1.1120.30
178_G325_T1.1100.30
175_H322_G1.1080.30
201_V221_W1.1080.30
461_Q509_D1.1070.30
230_V257_L1.1070.30
564_A568_L1.1030.30
222_S257_L1.1000.30
459_T476_L1.0970.29
560_K570_A1.0940.29
546_V562_Q1.0930.29
34_E66_A1.0920.29
148_H300_E1.0850.29
298_G307_G1.0810.29
453_T457_V1.0810.29
461_Q465_N1.0810.29
565_V568_L1.0780.29
552_K567_Q1.0740.29
561_A567_Q1.0730.29
489_S524_K1.0710.28
315_L327_Q1.0700.28
368_D373_Y1.0680.28
291_L295_S1.0660.28
155_G199_Y1.0630.28
460_A463_A1.0600.28
60_K247_V1.0590.28
557_N569_Q1.0570.28
361_D366_G1.0540.28
234_L257_L1.0530.28
59_Y67_V1.0530.28
188_G313_T1.0520.28
190_D274_A1.0510.28
562_Q568_L1.0490.28
272_Y294_F1.0480.28
118_L122_Q1.0470.28
343_D346_E1.0460.27
116_W169_D1.0450.27
142_D324_G1.0450.27
143_S298_G1.0420.27
197_Q369_Q1.0400.27
542_A548_A1.0400.27
203_A222_S1.0400.27
466_K473_K1.0390.27
221_W227_M1.0370.27
172_H324_G1.0340.27
346_E361_D1.0340.27
138_I216_L1.0340.27
233_S330_P1.0320.27
140_V252_E1.0310.27
313_T320_A1.0270.27
524_K562_Q1.0250.27
522_S536_S1.0210.27
230_V255_V1.0210.27
159_A371_F1.0200.27
532_N539_L1.0190.26
135_N296_T1.0190.26
540_K552_K1.0130.26
204_L278_S1.0120.26
552_K562_Q1.0050.26
219_I223_I1.0040.26
86_V182_A1.0020.26
223_I246_A1.0010.26
249_K284_A0.9950.26
159_A368_D0.9930.26
559_A574_K0.9920.25
540_K543_Q0.9900.25
179_I312_S0.9890.25
459_T484_K0.9870.25
562_Q577_L0.9860.25
133_G228_D0.9860.25
250_A257_L0.9850.25
562_Q566_N0.9840.25
276_Y302_E0.9810.25
226_R347_T0.9790.25
189_I313_T0.9780.25
230_V234_L0.9780.25
283_S368_D0.9740.25
561_A569_Q0.9710.25
499_A503_K0.9690.25
554_T557_N0.9670.25
201_V356_R0.9670.25
168_D202_K0.9650.25
89_N94_A0.9630.24
471_T481_D0.9630.24
132_T194_P0.9610.24
193_A337_A0.9600.24
565_V577_L0.9580.24
541_T547_S0.9580.24
330_P374_G0.9550.24
548_A557_N0.9550.24
194_P301_V0.9550.24
477_Q482_Q0.9550.24
280_V302_E0.9530.24
461_Q471_T0.9520.24
145_I377_Q0.9500.24
565_V570_A0.9450.24
180_I280_V0.9440.24
455_Q458_D0.9410.24
551_K560_K0.9400.24
458_D465_N0.9390.24
272_Y301_V0.9370.24
202_K423_T0.9360.24
222_S230_V0.9350.23
130_G195_E0.9350.23
155_G227_M0.9340.23
205_D251_Y0.9310.23
570_A577_L0.9310.23
534_V549_A0.9290.23
232_M273_P0.9280.23
559_A567_Q0.9270.23
198_I269_P0.9240.23
444_K447_K0.9240.23
543_Q565_V0.9230.23
148_H313_T0.9220.23
551_K557_N0.9170.23
262_G324_G0.9170.23
236_T261_S0.9150.23
469_N489_S0.9140.23
245_D249_K0.9130.23
562_Q570_A0.9110.23
112_N117_N0.9090.23
439_K445_V0.9090.23
131_L341_Q0.9070.23
566_N569_Q0.9040.22
500_E514_A0.9030.22
234_L368_D0.9010.22
543_Q548_A0.9010.22
144_G338_L0.9000.22
512_Q536_S0.9000.22
541_T569_Q0.8990.22
500_E505_K0.8930.22
557_N562_Q0.8890.22
39_Y80_D0.8890.22
150_D181_G0.8870.22
478_K487_I0.8870.22
142_D326_S0.8850.22
308_T337_A0.8810.22
218_G267_G0.8790.22
547_S564_A0.8780.22
227_M311_T0.8780.22
232_M250_A0.8750.22
539_L575_T0.8740.21
538_N546_V0.8740.21
204_L318_Y0.8740.21
214_S217_Q0.8720.21
302_E305_A0.8710.21
483_V490_K0.8700.21
117_N331_H0.8680.21
118_L247_V0.8640.21
542_A546_V0.8640.21
133_G196_A0.8640.21
253_Q268_K0.8640.21
236_T273_P0.8630.21
438_V444_K0.8630.21
532_N567_Q0.8630.21
453_T463_A0.8620.21
175_H305_A0.8590.21
548_A560_K0.8590.21
565_V576_A0.8590.21
182_A185_N0.8570.21
279_V301_V0.8570.21
468_P482_Q0.8560.21
94_A258_V0.8550.21
181_G192_I0.8530.21
313_T319_Y0.8500.21
462_T493_K0.8480.21
250_A368_D0.8480.21
329_T333_A0.8440.21
568_L573_D0.8430.21
340_K359_I0.8410.20
521_S536_S0.8400.20
476_L489_S0.8390.20
505_K516_G0.8360.20
135_N301_V0.8320.20
360_V380_A0.8320.20
210_G214_S0.8280.20
559_A570_A0.8260.20
179_I327_Q0.8260.20
231_N381_Q0.8260.20
549_A555_D0.8250.20
176_V232_M0.8250.20
173_G374_G0.8240.20
221_W369_Q0.8220.20
558_A572_K0.8210.20
45_K86_V0.8170.20
59_Y62_L0.8170.20
267_G283_S0.8140.20
235_G330_P0.8130.20
546_V549_A0.8100.20
538_N549_A0.8080.19
261_S278_S0.8080.19
142_D172_H0.8080.19
201_V371_F0.8060.19
541_T552_K0.8000.19
553_S558_A0.8000.19
382_A385_S0.7990.19
174_T325_T0.7990.19
229_I256_L0.7970.19
172_H328_A0.7970.19
236_T308_T0.7970.19
172_H260_A0.7960.19
478_K515_I0.7950.19
200_A231_N0.7930.19
541_T557_N0.7900.19
158_S174_T0.7880.19
165_S210_G0.7860.19
220_D232_M0.7860.19
473_K478_K0.7860.19
554_T572_K0.7850.19
300_E312_S0.7840.19
459_T462_T0.7840.19
225_N356_R0.7840.19
546_V551_K0.7830.19
124_K127_W0.7820.19
570_A576_A0.7790.19
273_P298_G0.7780.19
116_W120_P0.7770.19
143_S273_P0.7750.18
222_S234_L0.7750.18
562_Q569_Q0.7730.18
261_S308_T0.7730.18
554_T562_Q0.7710.18
247_V352_R0.7700.18
133_G297_T0.7690.18
158_S219_I0.7670.18
538_N551_K0.7660.18
255_V259_A0.7650.18
268_K331_H0.7650.18
478_K489_S0.7640.18
175_H298_G0.7640.18
256_L363_G0.7630.18
124_K329_T0.7630.18
542_A558_A0.7620.18
161_S234_L0.7620.18
456_T465_N0.7620.18
469_N475_N0.7620.18
216_L284_A0.7610.18
156_G246_A0.7610.18
149_D199_Y0.7600.18
146_S161_S0.7600.18
151_L350_Q0.7590.18
459_T463_A0.7580.18
77_L84_L0.7560.18
173_G324_G0.7540.18
222_S250_A0.7510.18
205_D351_L0.7510.18
457_V485_R0.7470.18
500_E517_K0.7470.18
554_T568_L0.7460.18
332_A381_Q0.7460.18
263_N324_G0.7460.18
569_Q578_Q0.7440.18
222_S226_R0.7440.18
461_Q470_G0.7430.18
508_V556_A0.7410.18
476_L481_D0.7410.18
275_A388_A0.7410.18
202_K276_Y0.7400.18
175_H179_I0.7400.18
551_K577_L0.7390.17
178_G327_Q0.7370.17
326_S330_P0.7370.17
541_T576_A0.7360.17
236_T264_D0.7350.17
470_G477_Q0.7340.17
476_L487_I0.7340.17
256_L348_N0.7340.17
333_A343_D0.7330.17
506_T510_S0.7290.17
231_N331_H0.7280.17
540_K550_E0.7270.17
298_G302_E0.7260.17
470_G481_D0.7250.17
40_K87_E0.7250.17
144_G326_S0.7240.17
161_S271_N0.7240.17
302_E306_P0.7230.17
222_S232_M0.7230.17
553_S560_K0.7210.17
477_Q485_R0.7200.17
449_E514_A0.7190.17
547_S560_K0.7190.17
265_G274_A0.7190.17
496_V511_A0.7170.17
36_I212_L0.7170.17
567_Q570_A0.7160.17
295_S359_I0.7160.17
191_G324_G0.7160.17
499_A510_S0.7150.17
135_N297_T0.7150.17
235_G326_S0.7130.17
512_Q519_P0.7130.17
305_A310_I0.7100.17
183_K197_Q0.7090.17
436_R446_A0.7080.17
230_V355_M0.7070.17
564_A572_K0.7060.17
487_I501_K0.7060.17
143_S391_E0.7040.17
558_A561_A0.7030.17
464_I478_K0.7030.17
150_D250_A0.7020.16
25_A59_Y0.7010.16
330_P337_A0.7000.16
229_I346_E0.7000.16
566_N576_A0.6990.16
567_Q575_T0.6990.16
194_P298_G0.6980.16
271_N293_S0.6980.16
558_A568_L0.6960.16
193_A254_G0.6950.16
488_A495_K0.6940.16
559_A566_N0.6930.16
553_S574_K0.6930.16
270_V351_L0.6930.16
549_A553_S0.6920.16
53_A77_L0.6920.16
283_S369_Q0.6920.16
175_H310_I0.6910.16
566_N570_A0.6890.16
505_K510_S0.6870.16
25_A63_P0.6860.16
440_D447_K0.6860.16
561_A568_L0.6860.16
302_E327_Q0.6850.16
246_A255_V0.6850.16
556_A564_A0.6840.16
297_T301_V0.6840.16
368_D371_F0.6840.16
303_F423_T0.6840.16
541_T559_A0.6830.16
551_K562_Q0.6830.16
314_Y346_E0.6820.16
233_S324_G0.6820.16
193_A228_D0.6820.16
151_L291_L0.6800.16
146_S158_S0.6800.16
262_G372_G0.6800.16
259_A371_F0.6790.16
133_G371_F0.6770.16
504_K536_S0.6770.16
524_K542_A0.6750.16
271_N296_T0.6740.16
203_A231_N0.6730.16
174_T205_D0.6730.16
219_I232_M0.6720.16
554_T571_G0.6710.16
204_L234_L0.6700.16
142_D262_G0.6690.16
545_S563_S0.6680.16
553_S562_Q0.6680.16
124_K177_A0.6670.16
561_A574_K0.6670.16
550_E558_A0.6670.16
352_R371_F0.6670.16
537_T551_K0.6670.16
458_D462_T0.6660.16
490_K493_K0.6650.16
183_K201_V0.6650.16
475_N504_K0.6630.16
127_W130_G0.6630.16
63_P74_V0.6630.16
155_G283_S0.6620.15
284_A328_A0.6610.15
123_V478_K0.6610.15
570_A578_Q0.6600.15
228_D267_G0.6590.15
158_S217_Q0.6570.15
268_K289_N0.6560.15
66_A304_S0.6560.15
564_A575_T0.6550.15
542_A560_K0.6540.15
109_T185_N0.6540.15
234_L246_A0.6530.15
226_R281_A0.6520.15
176_V298_G0.6520.15
543_Q553_S0.6500.15
560_K568_L0.6500.15
234_L269_P0.6500.15
556_A571_G0.6500.15
516_G537_T0.6490.15
551_K555_D0.6490.15
482_Q485_R0.6470.15
174_T297_T0.6470.15
182_A390_A0.6460.15
497_A504_K0.6460.15
548_A555_D0.6440.15
259_A367_R0.6440.15
85_Y89_N0.6440.15
179_I250_A0.6430.15
338_L358_N0.6420.15
163_T166_Y0.6410.15
197_Q308_T0.6410.15
439_K444_K0.6400.15
549_A554_T0.6400.15
536_S554_T0.6370.15
558_A566_N0.6360.15
306_P310_I0.6340.15
38_V357_K0.6320.15
461_Q490_K0.6320.15
470_G478_K0.6310.15
62_L140_V0.6310.15
260_A430_D0.6300.15
150_D340_K0.6300.15
123_V202_K0.6290.15
460_A470_G0.6290.15
148_H301_V0.6260.15
454_Q486_Y0.6250.15
80_D83_I0.6240.15
306_P331_H0.6240.15
435_Y441_A0.6240.15
143_S176_V0.6230.15
544_Q548_A0.6210.14
192_I308_T0.6190.14
544_Q560_K0.6190.14
541_T548_A0.6180.14
233_S328_A0.6180.14
342_R382_A0.6180.14
226_R255_V0.6180.14
235_G328_A0.6170.14
204_L308_T0.6160.14
141_I370_Q0.6160.14
255_V281_A0.6150.14
305_A327_Q0.6150.14
192_I334_A0.6150.14
126_A192_I0.6140.14
170_N331_H0.6140.14
236_T274_A0.6100.14
65_V389_A0.6090.14
572_K575_T0.6080.14
229_I255_V0.6080.14
533_K574_K0.6080.14
159_A201_V0.6070.14
232_M257_L0.6060.14
283_S409_A0.6040.14
259_A301_V0.6040.14
188_G238_S0.6040.14
545_S548_A0.6020.14
156_G371_F0.6020.14
250_A331_H0.6010.14
544_Q572_K0.6010.14
329_T334_A0.6000.14
219_I273_P0.6000.14
175_H302_E0.6000.14
531_L535_K0.5990.14
550_E557_N0.5990.14
343_D354_E0.5970.14
564_A574_K0.5960.14
179_I230_V0.5950.14
373_Y376_I0.5950.14
561_A576_A0.5950.14
564_A570_A0.5940.14
233_S325_T0.5920.14
324_G374_G0.5920.14
59_Y187_Y0.5920.14
86_V151_L0.5920.14
567_Q578_Q0.5900.14
203_A273_P0.5890.14
210_G215_L0.5870.14
548_A575_T0.5870.14
199_Y375_L0.5870.14
324_G372_G0.5850.14
560_K572_K0.5850.14
39_Y360_V0.5830.14
180_I196_A0.5830.14
201_V352_R0.5820.14
183_K287_E0.5810.14
546_V571_G0.5800.14
547_S556_A0.5790.14
509_D513_S0.5790.14
173_G326_S0.5790.14
215_L232_M0.5790.14
556_A577_L0.5770.13
566_N578_Q0.5770.13
539_L544_Q0.5770.13
428_R437_N0.5750.13
361_D373_Y0.5750.13
197_Q359_I0.5740.13
174_T267_G0.5740.13
527_L539_L0.5730.13
427_K431_K0.5730.13
549_A561_A0.5720.13
170_N244_H0.5710.13
280_V342_R0.5710.13
502_S505_K0.5690.13
541_T544_Q0.5690.13
197_Q221_W0.5690.13
554_T564_A0.5680.13
138_I338_L0.5680.13
563_S570_A0.5680.13
154_A221_W0.5670.13
263_N326_S0.5670.13
116_W371_F0.5660.13
548_A553_S0.5650.13
497_A502_S0.5650.13
453_T477_Q0.5650.13
51_S62_L0.5630.13
138_I358_N0.5620.13
201_V280_V0.5620.13
148_H178_G0.5610.13
261_S291_L0.5590.13
459_T493_K0.5580.13
231_N276_Y0.5570.13
114_E179_I0.5560.13
254_G399_Q0.5550.13
488_A492_A0.5540.13
169_D216_L0.5540.13
539_L562_Q0.5530.13
558_A565_V0.5530.13
156_G250_A0.5520.13
536_S547_S0.5510.13
469_N491_Q0.5510.13
568_L575_T0.5480.13
191_G326_S0.5480.13
490_K500_E0.5480.13
456_T479_R0.5480.13
549_A560_K0.5480.13
298_G305_A0.5460.13
478_K492_A0.5450.13
151_L160_V0.5450.13
130_G133_G0.5450.13
556_A561_A0.5440.13
485_R492_A0.5440.13
551_K570_A0.5440.13
132_T286_N0.5430.13
178_G313_T0.5410.13
298_G306_P0.5410.13
454_Q472_D0.5410.13
466_K471_T0.5400.13
550_E563_S0.5400.13
271_N327_Q0.5390.13
179_I264_D0.5390.13
303_F460_A0.5380.13
210_G292_A0.5370.13
568_L571_G0.5370.13
151_L342_R0.5360.13
402_A406_I0.5360.13
472_D487_I0.5360.13
562_Q576_A0.5350.13
389_A414_S0.5340.13
539_L557_N0.5330.13
205_D211_D0.5330.13
474_K481_D0.5310.13
291_L304_S0.5310.13
83_I363_G0.5310.13
194_P296_T0.5300.12
476_L484_K0.5300.12
564_A567_Q0.5300.12
81_P84_L0.5290.12
454_Q463_A0.5280.12
160_V382_A0.5280.12
140_V334_A0.5280.12
513_S532_N0.5260.12
356_R367_R0.5260.12
83_I358_N0.5250.12
151_L306_P0.5250.12
552_K574_K0.5250.12
542_A572_K0.5250.12
564_A578_Q0.5240.12
299_D357_K0.5240.12
218_G325_T0.5230.12
37_V226_R0.5230.12
557_N571_G0.5220.12
182_A189_I0.5210.12
539_L547_S0.5210.12
182_A391_E0.5210.12
465_N486_Y0.5210.12
270_V298_G0.5190.12
220_D249_K0.5180.12
548_A554_T0.5180.12
527_L564_A0.5180.12
561_A564_A0.5180.12
144_G172_H0.5180.12
210_G258_V0.5170.12
497_A510_S0.5170.12
192_I291_L0.5160.12
477_Q491_Q0.5150.12
183_K284_A0.5150.12
182_A199_Y0.5150.12
551_K569_Q0.5150.12
481_D484_K0.5140.12
543_Q575_T0.5120.12
90_V305_A0.5100.12
197_Q225_N0.5100.12
264_D296_T0.5100.12
554_T561_A0.5090.12
568_L577_L0.5080.12
466_K470_G0.5080.12
552_K564_A0.5080.12
542_A577_L0.5060.12
231_N250_A0.5060.12
303_F335_M0.5050.12
261_S273_P0.5050.12
142_D263_N0.5040.12
201_V296_T0.5040.12
60_K139_A0.5040.12
156_G200_A0.5030.12
570_A573_D0.5030.12
292_A311_T0.5020.12
146_S322_G0.5020.12
555_D566_N0.5010.12
510_S533_K0.5010.12
250_A296_T0.5000.12
45_K48_I0.5000.12
230_V273_P0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3whiA 2 0.538 100 0.431 Contact Map
3wiuA 2 0.5457 100 0.451 Contact Map
3t41A 1 0.538 100 0.466 Contact Map
3afgA 1 0.7225 100 0.469 Contact Map
4tr2A 2 0.5426 100 0.474 Contact Map
1r6vA 1 0.8837 100 0.476 Contact Map
1xf1A 2 0.6078 100 0.499 Contact Map
1gciA 1 0.4171 100 0.504 Contact Map
4mzdA 1 0.414 100 0.506 Contact Map
1r0rE 1 0.4186 100 0.512 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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