ODO2 - BACSU - GREMLIN Contacts

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ODO2 - Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex

UniProt:	P16263	Sequences: MAEIKVPELAESISEGTIAQWLKQPGDYVEQGEYLLELETDKVNVELTAEESGVLQEVLKDSGDTVQVGEIIGTISEGAGESSAPAPTEKTESKESVKEEKQAEPAAQEVSEEAQSEAKSRTIASPSARKLAREKGIDLSQVPTGDPLGRVRKQDVEAYEKPASKPAPQQKQQPQAQKAQQSFDKPVEVQKMSRRRQTIAKRLVEVQQTSAMLTTFNEVDMTAVMNLRKRRKDQFFEQNEVKLGFMSFFTKAVVAALKKYPLLNAEIQGDELIVKKFYDIGIAVAADEGLVVPVVRDADRLTFAGIEKEIGELAKKARNNKLTLSELQGGSFTITNGGTFGSLMSTPILNSPQVGILGMHKIQLRPVAIDEERFENRPMMYIALSYDHRIVDGKEAVGFLVTIKNLLEDPEQLLLEG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	417 (404)
Sequences:	7897 (5090)
Seq/√Len:	253.2

ECOLI - ODO2 ODP2
BACSU - ODO2 ODP2 ACOC ODB2
HALSA - Q9HN75

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
312_E	316_K	3.787	1.00
25_P	57_E	3.645	1.00
301_L	309_E	3.384	1.00
364_L	371_E	3.369	1.00
56_Q	76_S	3.246	1.00
259_K	402_T	3.245	1.00
315_K	319_N	3.186	1.00
23_K	33_E	3.175	1.00
188_E	276_K	3.038	1.00
61_D	64_D	2.902	1.00
189_V	271_E	2.898	1.00
368_A	374_F	2.870	1.00
23_K	55_L	2.766	1.00
309_E	312_E	2.689	1.00
135_K	160_E	2.650	1.00
316_K	326_E	2.637	1.00
250_T	280_I	2.594	1.00
266_E	275_K	2.592	1.00
218_E	365_R	2.556	1.00
138_D	141_Q	2.541	1.00
198_T	201_K	2.527	1.00
22_L	34_Y	2.515	1.00
253_V	332_F	2.504	1.00
260_Y	402_T	2.478	1.00
30_E	52_S	2.470	1.00
57_E	74_T	2.467	1.00
368_A	376_N	2.386	1.00
219_V	382_I	2.248	1.00
364_L	378_P	2.247	1.00
20_Q	62_S	2.214	1.00
3_E	74_T	2.206	1.00
212_M	385_S	2.176	1.00
220_D	377_R	2.169	1.00
190_Q	274_V	2.165	1.00
277_F	297_D	2.146	1.00
60_K	70_E	2.121	1.00
301_L	305_G	2.105	1.00
59_L	74_T	2.085	1.00
281_G	292_V	2.054	1.00
330_G	353_Q	1.993	1.00
28_Y	54_V	1.970	1.00
258_K	299_D	1.965	1.00
20_Q	37_E	1.959	1.00
257_L	332_F	1.955	1.00
55_L	73_G	1.940	1.00
59_L	71_I	1.938	1.00
369_I	373_R	1.932	1.00
369_I	375_E	1.928	1.00
254_V	278_Y	1.921	1.00
192_M	267_I	1.897	1.00
250_T	298_A	1.890	1.00
3_E	71_I	1.886	1.00
141_Q	159_Y	1.873	1.00
18_I	36_L	1.860	1.00
131_L	157_E	1.837	1.00
24_Q	27_D	1.836	1.00
253_V	403_I	1.817	1.00
233_D	237_E	1.814	1.00
153_K	157_E	1.805	1.00
15_E	65_T	1.795	1.00
186_P	276_K	1.791	1.00
31_Q	52_S	1.775	1.00
189_V	273_I	1.765	1.00
130_K	134_E	1.752	1.00
198_T	202_R	1.748	1.00
30_E	33_E	1.728	1.00
55_L	58_V	1.724	1.00
279_D	296_R	1.723	1.00
288_E	320_N	1.712	1.00
254_V	298_A	1.694	1.00
250_T	282_I	1.665	1.00
402_T	405_N	1.644	1.00
250_T	310_I	1.643	1.00
317_A	322_L	1.643	1.00
205_E	209_T	1.639	1.00
249_F	359_M	1.627	1.00
132_A	139_L	1.621	1.00
195_R	199_I	1.617	1.00
67_Q	70_E	1.614	1.00
265_A	274_V	1.607	1.00
202_R	205_E	1.601	1.00
282_I	310_I	1.600	1.00
137_I	142_V	1.591	1.00
236_F	242_K	1.580	1.00
223_A	226_N	1.573	1.00
36_L	72_I	1.563	1.00
262_L	274_V	1.561	1.00
188_E	274_V	1.559	1.00
22_L	37_E	1.549	1.00
225_M	245_F	1.543	1.00
255_A	406_L	1.538	1.00
157_E	161_K	1.528	1.00
297_D	300_R	1.522	1.00
124_A	139_L	1.519	1.00
207_Q	212_M	1.509	1.00
131_L	156_V	1.500	1.00
60_K	66_V	1.492	1.00
347_P	358_G	1.490	1.00
265_A	390_I	1.485	1.00
295_V	309_E	1.479	1.00
210_S	349_L	1.460	1.00
230_R	411_E	1.434	1.00
222_T	377_R	1.429	1.00
302_T	305_G	1.426	1.00
310_I	314_A	1.393	1.00
354_V	390_I	1.388	1.00
250_T	334_I	1.384	1.00
366_P	374_F	1.380	1.00
37_E	46_E	1.376	1.00
256_A	403_I	1.371	1.00
196_R	199_I	1.359	1.00
332_F	355_G	1.346	1.00
260_Y	398_G	1.332	1.00
268_Q	271_E	1.332	1.00
262_L	395_E	1.325	1.00
216_F	344_M	1.325	1.00
187_V	273_I	1.321	1.00
364_L	376_N	1.319	1.00
25_P	61_D	1.317	1.00
144_T	151_V	1.312	1.00
4_I	73_G	1.302	1.00
365_R	379_M	1.300	1.00
215_T	396_A	1.298	1.00
232_K	242_K	1.291	1.00
253_V	399_F	1.291	1.00
350_N	353_Q	1.288	1.00
201_K	205_E	1.283	1.00
204_V	208_Q	1.279	1.00
401_V	405_N	1.277	1.00
189_V	268_Q	1.269	1.00
382_I	403_I	1.267	1.00
54_V	76_S	1.256	1.00
187_V	276_K	1.246	1.00
357_L	403_I	1.241	1.00
154_Q	158_A	1.241	1.00
196_R	392_D	1.234	1.00
281_G	353_Q	1.217	1.00
5_K	71_I	1.207	1.00
229_K	233_D	1.203	1.00
19_A	44_N	1.200	1.00
366_P	376_N	1.191	1.00
144_T	150_R	1.187	1.00
137_I	160_E	1.181	1.00
131_L	135_K	1.180	1.00
224_V	248_F	1.180	1.00
191_K	271_E	1.177	1.00
215_T	386_Y	1.174	1.00
272_L	390_I	1.167	1.00
220_D	369_I	1.159	1.00
214_T	385_S	1.159	1.00
404_K	408_E	1.157	1.00
267_I	390_I	1.157	1.00
24_Q	58_V	1.150	1.00
323_T	326_E	1.140	1.00
154_Q	157_E	1.129	1.00
277_F	299_D	1.126	1.00
314_A	318_R	1.125	1.00
226_N	230_R	1.110	1.00
221_M	224_V	1.106	1.00
218_E	343_L	1.103	1.00
210_S	351_S	1.096	1.00
54_V	79_A	1.095	1.00
222_T	378_P	1.089	1.00
402_T	406_L	1.087	1.00
250_T	295_V	1.086	1.00
214_T	346_T	1.085	1.00
278_Y	299_D	1.085	1.00
263_L	355_G	1.082	1.00
146_D	155_D	1.081	1.00
279_D	297_D	1.078	1.00
234_Q	412_Q	1.073	1.00
122_T	151_V	1.071	1.00
253_V	355_G	1.070	1.00
213_L	386_Y	1.069	1.00
251_K	255_A	1.066	1.00
229_K	232_K	1.066	1.00
135_K	157_E	1.061	1.00
215_T	342_S	1.057	1.00
222_T	226_N	1.055	1.00
34_Y	46_E	1.052	1.00
285_A	398_G	1.046	1.00
226_N	229_K	1.044	1.00
143_P	159_Y	1.043	1.00
217_N	404_K	1.039	1.00
357_L	384_L	1.033	1.00
285_A	340_F	1.032	1.00
343_L	363_Q	1.032	1.00
279_D	294_V	1.029	1.00
362_I	378_P	1.025	1.00
250_T	306_I	1.024	1.00
268_Q	273_I	1.022	1.00
139_L	151_V	1.020	1.00
6_V	16_G	1.016	1.00
359_M	380_M	1.014	1.00
25_P	56_Q	1.011	1.00
297_D	301_L	1.010	1.00
187_V	277_F	1.009	1.00
137_I	156_V	1.008	1.00
316_K	323_T	1.007	1.00
204_V	210_S	1.004	1.00
291_V	322_L	1.003	1.00
332_F	399_F	1.001	1.00
221_M	362_I	0.999	1.00
263_L	391_V	0.998	1.00
221_M	380_M	0.994	1.00
132_A	137_I	0.992	1.00
369_I	377_R	0.991	1.00
367_V	379_M	0.990	1.00
25_P	58_V	0.988	1.00
13_I	16_G	0.984	1.00
388_H	393_G	0.981	1.00
384_L	400_L	0.976	1.00
197_Q	270_D	0.968	1.00
367_V	377_R	0.967	1.00
337_G	345_S	0.962	1.00
332_F	357_L	0.962	1.00
51_E	75_I	0.961	1.00
312_E	315_K	0.960	1.00
4_I	75_I	0.959	1.00
124_A	132_A	0.958	1.00
212_M	349_L	0.957	1.00
29_V	55_L	0.957	1.00
364_L	370_D	0.951	1.00
394_K	398_G	0.951	1.00
66_V	70_E	0.951	1.00
255_A	413_L	0.950	1.00
9_L	16_G	0.947	1.00
24_Q	62_S	0.947	1.00
18_I	60_K	0.945	1.00
216_F	346_T	0.944	1.00
239_N	308_K	0.943	1.00
139_L	142_V	0.940	1.00
21_W	58_V	0.939	1.00
332_F	384_L	0.939	1.00
285_A	394_K	0.937	1.00
231_R	243_L	0.937	1.00
132_A	151_V	0.934	1.00
197_Q	201_K	0.931	1.00
295_V	301_L	0.922	1.00
35_L	49_A	0.918	1.00
219_V	404_K	0.917	1.00
295_V	310_I	0.912	1.00
29_V	49_A	0.911	1.00
18_I	72_I	0.909	1.00
247_S	306_I	0.905	1.00
199_I	203_L	0.905	1.00
255_A	258_K	0.905	1.00
128_A	153_K	0.904	1.00
158_A	161_K	0.900	1.00
15_E	67_Q	0.899	1.00
291_V	327_L	0.895	1.00
144_T	149_G	0.892	1.00
127_S	153_K	0.892	1.00
93_S	96_S	0.891	1.00
22_L	46_E	0.888	1.00
225_M	378_P	0.885	1.00
132_A	142_V	0.884	1.00
215_T	360_H	0.884	1.00
247_S	303_F	0.878	1.00
259_K	406_L	0.877	1.00
4_I	35_L	0.877	1.00
322_L	327_L	0.875	1.00
60_K	64_D	0.873	1.00
158_A	162_P	0.869	1.00
253_V	357_L	0.867	1.00
215_T	400_L	0.865	1.00
145_G	152_R	0.864	0.99
207_Q	211_A	0.863	0.99
258_K	278_Y	0.859	0.99
17_T	63_G	0.857	0.99
145_G	155_D	0.857	0.99
88_T	91_T	0.856	0.99
6_V	38_L	0.856	0.99
305_G	308_K	0.855	0.99
38_L	47_L	0.852	0.99
207_Q	210_S	0.848	0.99
17_T	65_T	0.848	0.99
279_D	330_G	0.839	0.99
187_V	275_K	0.838	0.99
128_A	156_V	0.837	0.99
230_R	409_D	0.835	0.99
249_F	380_M	0.831	0.99
343_L	381_Y	0.820	0.99
281_G	330_G	0.814	0.99
156_V	159_Y	0.813	0.99
227_L	248_F	0.809	0.99
32_G	48_T	0.808	0.99
145_G	149_G	0.805	0.99
128_A	132_A	0.805	0.99
386_Y	396_A	0.804	0.99
219_V	407_L	0.804	0.99
192_M	272_L	0.803	0.99
58_V	61_D	0.802	0.99
359_M	382_I	0.801	0.99
94_K	97_V	0.801	0.99
305_G	309_E	0.798	0.99
146_D	149_G	0.798	0.99
195_R	286_A	0.796	0.99
355_G	384_L	0.794	0.99
355_G	391_V	0.794	0.99
89_E	93_S	0.793	0.99
304_A	308_K	0.792	0.99
8_E	11_E	0.791	0.99
58_V	64_D	0.790	0.99
214_T	383_A	0.789	0.99
144_T	155_D	0.788	0.99
243_L	247_S	0.787	0.99
9_L	38_L	0.785	0.99
207_Q	348_I	0.777	0.99
160_E	163_A	0.774	0.99
202_R	350_N	0.773	0.99
243_L	248_F	0.770	0.99
194_R	197_Q	0.767	0.99
343_L	361_K	0.765	0.99
207_Q	385_S	0.763	0.99
279_D	326_E	0.760	0.99
124_A	128_A	0.760	0.99
192_M	269_G	0.760	0.99
218_E	363_Q	0.760	0.99
132_A	138_D	0.755	0.99
215_T	337_G	0.748	0.99
410_P	413_L	0.746	0.99
103_A	106_A	0.745	0.99
23_K	27_D	0.744	0.98
284_V	318_R	0.743	0.98
245_F	362_I	0.742	0.98
122_T	140_S	0.740	0.98
337_G	358_G	0.740	0.98
260_Y	395_E	0.740	0.98
195_R	288_E	0.737	0.98
249_F	407_L	0.735	0.98
142_V	159_Y	0.735	0.98
163_A	166_P	0.733	0.98
301_L	312_E	0.730	0.98
206_V	212_M	0.729	0.98
207_Q	214_T	0.729	0.98
31_Q	49_A	0.729	0.98
221_M	407_L	0.729	0.98
135_K	161_K	0.726	0.98
124_A	151_V	0.725	0.98
92_E	95_E	0.725	0.98
161_K	164_S	0.724	0.98
56_Q	74_T	0.722	0.98
364_L	368_A	0.722	0.98
35_L	73_G	0.720	0.98
370_D	373_R	0.720	0.98
132_A	156_V	0.718	0.98
203_L	292_V	0.718	0.98
263_L	354_V	0.718	0.98
56_Q	78_G	0.717	0.98
87_P	90_K	0.714	0.98
294_V	329_G	0.713	0.98
104_E	108_Q	0.713	0.98
8_E	12_S	0.712	0.98
14_S	67_Q	0.712	0.98
131_L	153_K	0.711	0.98
384_L	396_A	0.710	0.98
176_A	179_A	0.708	0.98
102_Q	106_A	0.707	0.98
241_V	308_K	0.704	0.98
232_K	236_F	0.702	0.98
164_S	167_A	0.702	0.98
9_L	12_S	0.702	0.98
217_N	342_S	0.701	0.98
279_D	353_Q	0.701	0.98
403_I	407_L	0.700	0.98
29_V	75_I	0.699	0.98
255_A	259_K	0.699	0.98
312_E	326_E	0.698	0.98
296_R	325_S	0.697	0.98
330_G	350_N	0.697	0.98
399_F	403_I	0.697	0.98
264_N	331_S	0.694	0.98
263_L	395_E	0.693	0.98
186_P	277_F	0.692	0.98
216_F	383_A	0.691	0.98
200_A	267_I	0.689	0.98
223_A	377_R	0.688	0.98
16_G	43_V	0.688	0.98
344_M	381_Y	0.686	0.97
128_A	151_V	0.686	0.97
9_L	47_L	0.684	0.97
6_V	66_V	0.684	0.97
221_M	378_P	0.684	0.97
89_E	92_E	0.683	0.97
257_L	263_L	0.682	0.97
100_E	103_A	0.681	0.97
349_L	355_G	0.681	0.97
286_A	291_V	0.681	0.97
253_V	256_A	0.680	0.97
256_A	402_T	0.679	0.97
54_V	78_G	0.678	0.97
19_A	63_G	0.678	0.97
246_M	249_F	0.678	0.97
345_S	360_H	0.673	0.97
316_K	322_L	0.672	0.97
131_L	137_I	0.670	0.97
16_G	38_L	0.670	0.97
257_L	278_Y	0.670	0.97
220_D	367_V	0.664	0.97
206_V	351_S	0.664	0.97
25_P	74_T	0.663	0.97
294_V	330_G	0.662	0.97
86_A	91_T	0.661	0.97
18_I	58_V	0.661	0.97
122_T	139_L	0.660	0.97
246_M	339_T	0.660	0.97
28_Y	78_G	0.659	0.97
218_E	381_Y	0.658	0.97
28_Y	52_S	0.658	0.97
234_Q	238_Q	0.657	0.97
223_A	411_E	0.656	0.97
249_F	334_I	0.655	0.97
409_D	412_Q	0.655	0.97
218_E	379_M	0.654	0.97
337_G	342_S	0.654	0.97
49_A	52_S	0.652	0.97
316_K	321_K	0.652	0.97
382_I	400_L	0.651	0.97
296_R	309_E	0.651	0.97
358_G	385_S	0.651	0.97
214_T	358_G	0.648	0.96
156_V	160_E	0.648	0.96
95_E	98_K	0.647	0.96
340_F	397_V	0.647	0.96
234_Q	237_E	0.646	0.96
137_I	141_Q	0.644	0.96
204_V	207_Q	0.644	0.96
91_T	94_K	0.643	0.96
333_T	353_Q	0.642	0.96
34_Y	37_E	0.641	0.96
280_I	332_F	0.641	0.96
85_P	89_E	0.638	0.96
294_V	353_Q	0.637	0.96
99_E	103_A	0.636	0.96
181_Q	184_D	0.636	0.96
324_L	328_Q	0.636	0.96
236_F	239_N	0.636	0.96
185_K	277_F	0.635	0.96
22_L	25_P	0.635	0.96
257_L	399_F	0.635	0.96
108_Q	112_E	0.633	0.96
32_G	52_S	0.632	0.96
360_H	397_V	0.631	0.96
146_D	152_R	0.631	0.96
263_L	399_F	0.629	0.96
330_G	351_S	0.629	0.96
99_E	102_Q	0.628	0.96
369_I	374_F	0.627	0.96
49_A	75_I	0.627	0.96
190_Q	262_L	0.624	0.96
246_M	336_N	0.624	0.96
369_I	376_N	0.622	0.96
19_A	22_L	0.622	0.96
262_L	265_A	0.621	0.95
16_G	40_T	0.621	0.95
246_M	334_I	0.620	0.95
85_P	88_T	0.619	0.95
59_L	70_E	0.616	0.95
237_E	240_E	0.613	0.95
285_A	395_E	0.611	0.95
217_N	400_L	0.609	0.95
344_M	383_A	0.608	0.95
183_F	186_P	0.608	0.95
300_R	305_G	0.608	0.95
3_E	59_L	0.608	0.95
77_E	80_G	0.607	0.95
159_Y	163_A	0.606	0.95
224_V	407_L	0.606	0.95
368_A	371_E	0.605	0.95
93_S	97_V	0.604	0.95
337_G	360_H	0.603	0.95
282_I	334_I	0.603	0.95
192_M	268_Q	0.603	0.95
370_D	376_N	0.603	0.95
4_I	50_E	0.602	0.95
106_A	109_E	0.601	0.95
254_V	258_K	0.600	0.95
228_R	232_K	0.600	0.95
246_M	282_I	0.599	0.95
364_L	374_F	0.598	0.94
325_S	328_Q	0.598	0.94
309_E	313_L	0.598	0.94
185_K	276_K	0.594	0.94
311_G	315_K	0.593	0.94
225_M	362_I	0.591	0.94
102_Q	105_P	0.591	0.94
149_G	155_D	0.591	0.94
23_K	73_G	0.591	0.94
231_R	234_Q	0.588	0.94
192_M	271_E	0.585	0.94
127_S	131_L	0.585	0.94
142_V	155_D	0.585	0.94
209_T	351_S	0.583	0.94
185_K	279_D	0.582	0.94
87_P	91_T	0.582	0.94
5_K	69_G	0.581	0.94
227_L	411_E	0.581	0.94
252_A	407_L	0.580	0.94
323_T	328_Q	0.580	0.94
232_K	240_E	0.579	0.93
309_E	316_K	0.577	0.93
102_Q	108_Q	0.577	0.93
78_G	81_E	0.577	0.93
244_G	307_E	0.575	0.93
324_L	327_L	0.574	0.93
165_K	168_P	0.573	0.93
186_P	297_D	0.572	0.93
103_A	109_E	0.572	0.93
365_R	381_Y	0.572	0.93
88_T	92_E	0.570	0.93
347_P	385_S	0.570	0.93
233_D	236_F	0.569	0.93
163_A	167_A	0.569	0.93
349_L	385_S	0.568	0.93
204_V	211_A	0.567	0.93
90_K	94_K	0.566	0.93
279_D	292_V	0.566	0.93
405_N	412_Q	0.565	0.93
37_E	44_N	0.565	0.93
293_P	330_G	0.564	0.93
116_S	120_S	0.563	0.93
18_I	50_E	0.562	0.92
21_W	60_K	0.562	0.92
105_P	109_E	0.561	0.92
211_A	389_R	0.560	0.92
10_A	45_V	0.560	0.92
86_A	90_K	0.560	0.92
142_V	156_V	0.559	0.92
275_K	331_S	0.559	0.92
282_I	335_T	0.557	0.92
366_P	377_R	0.557	0.92
28_Y	55_L	0.554	0.92
131_L	160_E	0.553	0.92
347_P	383_A	0.551	0.92
13_I	68_V	0.550	0.92
344_M	347_P	0.549	0.92
280_I	306_I	0.549	0.92
206_V	349_L	0.549	0.92
40_T	43_V	0.549	0.92
13_I	360_H	0.546	0.91
95_E	104_E	0.546	0.91
34_Y	48_T	0.546	0.91
256_A	406_L	0.545	0.91
39_E	194_R	0.542	0.91
163_A	168_P	0.542	0.91
278_Y	331_S	0.542	0.91
137_I	159_Y	0.541	0.91
398_G	401_V	0.541	0.91
292_V	353_Q	0.540	0.91
99_E	104_E	0.540	0.91
284_V	313_L	0.539	0.91
266_E	277_F	0.537	0.91
191_K	194_R	0.537	0.91
36_L	47_L	0.536	0.91
97_V	100_E	0.535	0.91
92_E	96_S	0.534	0.90
59_L	72_I	0.534	0.90
220_D	223_A	0.533	0.90
216_F	381_Y	0.532	0.90
222_T	367_V	0.532	0.90
195_R	198_T	0.532	0.90
82_S	85_P	0.531	0.90
296_R	326_E	0.531	0.90
142_V	151_V	0.531	0.90
196_R	200_A	0.531	0.90
38_L	44_N	0.529	0.90
9_L	72_I	0.526	0.90
354_V	391_V	0.526	0.90
298_A	306_I	0.525	0.90
308_K	312_E	0.524	0.90
82_S	86_A	0.524	0.90
168_P	174_P	0.524	0.90
287_D	319_N	0.524	0.90
202_R	352_P	0.523	0.90
364_L	369_I	0.523	0.90
385_S	397_V	0.522	0.89
6_V	45_V	0.522	0.89
262_L	390_I	0.522	0.89
160_E	164_S	0.521	0.89
395_E	398_G	0.521	0.89
114_A	117_E	0.520	0.89
206_V	210_S	0.520	0.89
21_W	36_L	0.519	0.89
169_Q	176_A	0.518	0.89
349_L	352_P	0.517	0.89
275_K	354_V	0.512	0.89
262_L	272_L	0.512	0.89
306_I	313_L	0.511	0.88
76_S	79_A	0.510	0.88
214_T	347_P	0.510	0.88
104_E	107_A	0.509	0.88
357_L	382_I	0.508	0.88
6_V	73_G	0.508	0.88
373_R	376_N	0.507	0.88
100_E	104_E	0.505	0.88
12_S	50_E	0.505	0.88
157_E	160_E	0.504	0.88
101_K	104_E	0.504	0.88
25_P	28_Y	0.503	0.88
5_K	70_E	0.503	0.88
202_R	351_S	0.502	0.88
94_K	98_K	0.502	0.88
92_E	98_K	0.500	0.87
150_R	155_D	0.500	0.87
190_Q	272_L	0.500	0.87

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3dvaI	1	0.1007	100	0.147	Contact Map
2ii3A	4	0.554	100	0.456	Contact Map
1sczA	4	0.5588	100	0.457	Contact Map
4n72A	3	0.5851	100	0.462	Contact Map
1dpbA	4	0.5779	100	0.462	Contact Map
3maeA	3	0.5683	100	0.464	Contact Map
3b8kA	1	0.5707	100	0.466	Contact Map
3l60A	3	0.5372	100	0.476	Contact Map
3rqcA	4	0.5228	100	0.489	Contact Map
2xt6A	2	0.458	100	0.517	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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