GREMLIN Database
PYRG - CTP synthase
UniProt: P13242 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 535 (528)
Sequences: 2959 (1271)
Seq/√Len: 55.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
368_K372_E4.5931.00
449_V523_G4.5851.00
294_G346_T4.1131.00
292_T325_K4.0821.00
292_T327_K3.8691.00
367_T386_V3.7101.00
290_T325_K3.7081.00
400_G412_Y3.6201.00
374_N499_P3.5731.00
166_G169_N3.4381.00
293_I348_G3.2741.00
327_K346_T3.2591.00
24_L261_V3.2281.00
446_A492_I3.2221.00
435_L456_Y3.1091.00
367_T377_F3.0081.00
367_T501_F2.9601.00
253_Q258_D2.8011.00
365_V368_K2.7971.00
171_M208_I2.7951.00
471_Q475_E2.7681.00
445_K448_E2.7671.00
247_S285_S2.7001.00
444_T479_V2.6261.00
410_T413_P2.5951.00
349_I370_A2.5831.00
317_G324_V2.5611.00
391_Y395_V2.5341.00
322_T529_V2.5201.00
386_V389_I2.5181.00
327_K345_G2.5151.00
398_L472_Q2.4671.00
447_F453_E2.4611.00
374_N497_D2.4511.00
33_L137_V2.3991.00
492_I506_F2.3701.00
243_D247_S2.3571.00
377_F387_A2.3501.00
479_V496_K2.3311.00
123_K164_D2.3251.00
20_V210_V2.2941.00
234_K263_E2.2771.00
335_T338_N2.2761.00
398_L412_Y2.2661.00
172_Y204_I2.2601.00
96_S100_K2.2491.00
208_I257_L2.2461.00
198_E201_S2.2431.00
442_E447_F2.2181.00
182_K214_E2.2061.00
320_F526_G2.1831.00
80_D516_R2.1831.00
400_G411_Q2.1721.00
446_A481_S2.1701.00
219_Q223_D2.1661.00
120_N124_D2.1571.00
396_L473_M2.1281.00
289_Q322_T2.1211.00
412_Y469_F2.0621.00
403_S406_I2.0591.00
294_G329_I2.0441.00
445_K502_V1.9681.00
250_L278_K1.9631.00
404_A413_P1.9341.00
223_D233_T1.9321.00
98_V118_I1.9301.00
484_S487_G1.8791.00
442_E453_E1.8760.99
310_V328_W1.8730.99
161_M165_I1.8680.99
402_H407_D1.8630.99
444_T481_S1.8620.99
441_E474_E1.8600.99
63_D435_L1.8590.99
473_M478_F1.8550.99
97_T121_E1.8540.99
288_S321_D1.8450.99
500_W524_F1.8440.99
55_Q110_G1.8230.99
387_A501_F1.7990.99
351_V377_F1.7870.99
360_V386_V1.7840.99
63_D82_N1.7820.99
85_K93_K1.7680.99
127_Y161_M1.7420.99
465_F473_M1.7370.99
526_G530_E1.7270.99
29_K80_D1.7260.99
398_L469_F1.7210.99
290_T323_D1.7130.99
449_V502_V1.7080.99
388_S414_I1.6990.99
471_Q474_E1.6750.99
243_D285_S1.6660.99
121_E124_D1.6540.99
279_E283_K1.6420.99
4_Y130_G1.6340.99
377_F386_V1.6020.98
484_S488_R1.6000.98
283_K321_D1.5980.98
98_V107_Y1.5870.98
361_E364_I1.5810.98
470_R483_T1.5660.98
374_N498_H1.5660.98
382_L406_I1.5590.98
472_Q475_E1.5390.98
378_L524_F1.5300.98
289_Q529_V1.5240.98
176_T192_T1.5230.98
500_W523_G1.5220.98
178_V217_I1.5200.98
14_S184_A1.5180.98
30_N274_M1.5070.98
415_I465_F1.4950.97
360_V406_I1.4950.97
396_L472_Q1.4890.97
29_K81_I1.4790.97
348_G524_F1.4790.97
124_D128_R1.4740.97
137_V265_M1.4640.97
335_T339_I1.4550.97
446_A502_V1.4530.97
441_E479_V1.4510.97
465_F470_R1.4390.97
350_I524_F1.4240.97
163_S230_D1.4190.96
437_P454_V1.4180.96
398_L411_Q1.4180.96
388_S493_I1.4180.96
449_V500_W1.4140.96
155_L202_L1.4100.96
235_A260_L1.4090.96
174_H195_S1.4070.96
438_C506_F1.3990.96
360_V382_L1.3960.96
3_K169_N1.3940.96
101_K106_D1.3920.96
511_K518_Q1.3810.96
435_L511_K1.3800.96
391_Y476_Q1.3780.96
438_C482_G1.3700.96
334_V366_A1.3680.96
400_G407_D1.3610.96
21_A139_I1.3590.95
238_E255_Q1.3420.95
97_T125_R1.3410.95
239_C252_L1.3410.95
440_L446_A1.3370.95
209_I225_I1.3370.95
437_P456_Y1.3340.95
36_T87_S1.3320.95
24_L173_I1.3310.95
384_M493_I1.3260.95
237_I260_L1.3230.95
334_V342_L1.3220.95
467_N470_R1.3200.95
256_G259_K1.3100.94
384_M465_F1.3060.94
171_M264_H1.3050.94
388_S465_F1.3050.94
330_N333_E1.3030.94
390_E394_N1.3010.94
44_I91_T1.2950.94
63_D511_K1.2870.94
168_E266_K1.2860.94
37_I79_I1.2840.94
439_K454_V1.2820.94
292_T346_T1.2790.94
44_I118_I1.2680.93
367_T390_E1.2610.93
142_I158_I1.2600.93
127_Y165_I1.2570.93
295_L309_V1.2540.93
242_A251_E1.2490.93
319_A517_P1.2470.93
38_Q140_T1.2470.93
348_G528_S1.2400.93
7_V139_I1.2380.93
478_F493_I1.2330.92
197_K201_S1.2230.92
421_Q424_V1.2220.92
416_D421_Q1.2150.92
402_H410_T1.2110.92
293_I528_S1.2100.92
387_A503_A1.2090.92
480_F483_T1.2090.92
164_D172_Y1.2070.92
54_Y301_E1.2040.92
213_T238_E1.2030.92
368_K394_N1.2010.91
26_R29_K1.2000.91
82_N513_R1.1960.91
126_V161_M1.1930.91
439_K453_E1.1920.91
284_V318_Y1.1880.91
292_T345_G1.1820.91
91_T118_I1.1800.91
158_I172_Y1.1750.91
108_L427_L1.1630.90
187_L218_S1.1620.90
244_N285_S1.1600.90
207_N264_H1.1590.90
218_S221_M1.1590.90
396_L476_Q1.1520.90
282_N286_N1.1460.89
496_K499_P1.1460.89
93_K125_R1.1420.89
443_G448_E1.1410.89
5_I171_M1.1390.89
341_E344_S1.1360.89
162_K170_V1.1360.89
443_G447_F1.1340.89
440_L482_G1.1340.89
95_Y114_V1.1320.89
440_L444_T1.1290.89
467_N490_V1.1280.89
20_V175_C1.1260.89
40_F140_T1.1180.88
40_F48_P1.1170.88
301_E330_N1.1150.88
483_T487_G1.1120.88
404_A410_T1.1110.88
350_I380_I1.1100.88
445_K500_W1.1050.88
349_I375_I1.1050.88
97_T101_K1.0950.87
213_T240_E1.0920.87
80_D513_R1.0910.87
399_K412_Y1.0910.87
495_L498_H1.0880.87
472_Q476_Q1.0850.87
171_M261_V1.0830.87
3_K265_M1.0820.87
200_R230_D1.0800.86
260_L264_H1.0780.86
377_F501_F1.0740.86
391_Y478_F1.0720.86
334_V338_N1.0690.86
351_V387_A1.0680.86
219_Q233_T1.0650.86
313_L324_V1.0640.86
137_V267_L1.0630.86
480_F490_V1.0470.85
387_A493_I1.0460.85
26_R30_N1.0460.85
250_L281_V1.0420.84
19_I248_I1.0380.84
259_K263_E1.0370.84
287_L321_D1.0320.84
20_V239_C1.0300.84
419_P488_R1.0250.83
162_K172_Y1.0220.83
388_S473_M1.0220.83
378_L502_V1.0190.83
296_V331_A1.0150.83
412_Y472_Q1.0120.83
40_F74_H1.0080.82
361_E393_R1.0040.82
36_T138_V1.0040.82
350_I363_K1.0030.82
392_A473_M1.0020.82
196_V206_P1.0020.82
449_V524_F1.0010.82
155_L204_I1.0010.82
33_L269_C0.9990.82
407_D410_T0.9960.82
40_F126_V0.9950.82
247_S281_V0.9940.81
437_P485_P0.9930.81
20_V252_L0.9930.81
173_I261_V0.9900.81
523_G526_G0.9890.81
404_A416_D0.9800.81
8_T174_H0.9800.81
89_V125_R0.9790.80
334_V365_V0.9780.80
244_N284_V0.9780.80
456_Y511_K0.9780.80
446_A504_S0.9780.80
200_R205_Q0.9760.80
474_E480_F0.9730.80
280_L318_Y0.9700.80
350_I370_A0.9690.80
343_T346_T0.9660.80
303_P328_W0.9620.79
309_V380_I0.9590.79
225_I236_V0.9570.79
416_D419_P0.9560.79
417_L421_Q0.9560.79
244_N281_V0.9500.78
327_K342_L0.9470.78
440_L447_F0.9460.78
371_R390_E0.9410.78
329_I346_T0.9340.77
336_E365_V0.9310.77
335_T365_V0.9280.77
262_C269_C0.9260.77
146_V155_L0.9250.77
309_V353_G0.9220.76
278_K282_N0.9200.76
388_S478_F0.9170.76
316_A522_K0.9160.76
216_P240_E0.9120.76
165_I169_N0.9100.75
52_S55_Q0.9070.75
162_K167_R0.9070.75
253_Q272_A0.9040.75
294_G327_K0.9030.75
121_E125_R0.8990.74
167_R207_N0.8960.74
211_V225_I0.8900.74
367_T389_I0.8900.74
156_E159_R0.8900.74
416_D422_K0.8890.74
29_K79_I0.8870.73
258_D272_A0.8860.73
100_K426_D0.8800.73
114_V118_I0.8770.73
33_L262_C0.8770.73
81_I513_R0.8760.73
382_L403_S0.8750.72
95_Y153_P0.8740.72
38_Q48_P0.8740.72
495_L501_F0.8740.72
455_V518_Q0.8720.72
263_E266_K0.8690.72
104_R426_D0.8670.72
130_G138_V0.8650.72
418_L421_Q0.8650.72
295_L310_V0.8620.71
48_P74_H0.8610.71
137_V262_C0.8600.71
83_L87_S0.8570.71
317_G525_I0.8550.71
37_I87_S0.8550.71
340_A373_N0.8550.71
26_R515_T0.8540.71
108_L431_L0.8530.71
304_D309_V0.8520.70
312_S316_A0.8520.70
254_K278_K0.8520.70
391_Y495_L0.8510.70
192_T225_I0.8480.70
86_F128_R0.8470.70
447_F451_Q0.8450.70
234_K260_L0.8450.70
316_A320_F0.8430.70
251_E254_K0.8420.70
257_L261_V0.8410.69
320_F525_I0.8410.69
98_V155_L0.8410.69
339_I365_V0.8400.69
417_L422_K0.8310.69
339_I342_L0.8290.68
492_I504_S0.8270.68
31_R258_D0.8260.68
307_I314_R0.8240.68
182_K215_M0.8240.68
44_I98_V0.8230.68
210_V239_C0.8190.67
89_V304_D0.8180.67
179_P192_T0.8180.67
216_P238_E0.8170.67
180_Y184_A0.8170.67
316_A525_I0.8150.67
213_T217_I0.8140.67
242_A248_I0.8130.67
384_M504_S0.8130.67
437_P484_S0.8120.67
289_Q321_D0.8080.66
480_F493_I0.8080.66
208_I260_L0.8070.66
15_L20_V0.8050.66
130_G135_A0.8050.66
127_Y164_D0.8020.66
30_N272_A0.8010.66
34_N134_N0.7970.65
344_S369_Y0.7970.65
33_L136_D0.7960.65
338_N341_E0.7910.65
396_L478_F0.7910.65
374_N496_K0.7880.64
445_K449_V0.7870.64
158_I170_V0.7860.64
399_K411_Q0.7830.64
459_H491_E0.7780.63
162_K230_D0.7760.63
40_F89_V0.7760.63
187_L221_M0.7760.63
316_A324_V0.7740.63
439_K487_G0.7740.63
445_K497_D0.7720.63
176_T179_P0.7710.63
469_F472_Q0.7680.62
439_K485_P0.7670.62
457_E518_Q0.7650.62
291_I528_S0.7650.62
412_Y468_E0.7640.62
369_Y373_N0.7610.62
389_I402_H0.7610.62
292_T347_D0.7590.61
94_I125_R0.7590.61
63_D456_Y0.7580.61
222_K255_Q0.7560.61
294_G347_D0.7560.61
444_T482_G0.7550.61
222_K238_E0.7550.61
329_I334_V0.7520.61
367_T387_A0.7520.61
344_S373_N0.7500.61
364_I386_V0.7490.60
446_A503_A0.7450.60
38_Q87_S0.7440.60
483_T490_V0.7430.60
97_T100_K0.7430.60
88_N108_L0.7410.60
60_F82_N0.7410.60
183_A226_A0.7400.59
499_P531_A0.7390.59
66_A85_K0.7380.59
60_F513_R0.7360.59
129_A138_V0.7340.59
349_I524_F0.7340.59
517_P522_K0.7330.59
239_C255_Q0.7320.59
15_L175_C0.7290.58
523_G527_A0.7260.58
276_E515_T0.7220.58
350_I387_A0.7180.57
201_S484_S0.7170.57
333_E342_L0.7160.57
62_T66_A0.7160.57
209_I231_I0.7150.57
38_Q139_I0.7130.57
123_K160_Q0.7120.57
168_E264_H0.7110.56
380_I504_S0.7110.56
363_K386_V0.7100.56
348_G378_L0.7100.56
119_T160_Q0.7090.56
184_A241_D0.7090.56
437_P486_D0.7090.56
115_I119_T0.7070.56
265_M270_K0.7050.56
62_T68_T0.7050.56
370_A377_F0.7040.56
368_K373_N0.7020.55
187_L215_M0.7010.55
94_I121_E0.6990.55
493_I503_A0.6950.55
441_E483_T0.6950.55
31_R262_C0.6950.55
51_M59_V0.6940.55
235_A264_H0.6920.54
309_V352_P0.6920.54
420_E431_L0.6910.54
253_Q271_E0.6900.54
438_C446_A0.6890.54
82_N435_L0.6880.54
165_I170_V0.6880.54
178_V238_E0.6860.54
281_V285_S0.6850.54
334_V339_I0.6850.54
287_L323_D0.6850.54
8_T195_S0.6840.54
217_I221_M0.6840.54
114_V149_I0.6840.54
197_K200_R0.6830.53
181_I184_A0.6830.53
38_Q89_V0.6820.53
276_E279_E0.6790.53
113_Q150_E0.6790.53
296_V351_V0.6790.53
303_P310_V0.6770.53
162_K207_N0.6750.53
441_E444_T0.6750.53
522_K526_G0.6740.52
361_E402_H0.6730.52
378_L523_G0.6720.52
406_I410_T0.6700.52
208_I255_Q0.6700.52
15_L177_L0.6690.52
232_D264_H0.6690.52
336_E339_I0.6690.52
54_Y60_F0.6670.52
470_R480_F0.6660.52
120_N223_D0.6650.52
482_G492_I0.6640.51
443_G479_V0.6640.51
259_K269_C0.6640.51
398_L410_T0.6610.51
332_E358_R0.6600.51
339_I343_T0.6590.51
470_R490_V0.6590.51
391_Y473_M0.6590.51
345_G375_I0.6590.51
4_Y127_Y0.6560.51
247_S250_L0.6550.50
316_A319_A0.6550.50
93_K97_T0.6540.50
48_P180_Y0.6530.50
104_R427_L0.6530.50
142_I155_L0.6520.50
366_A370_A0.6510.50
447_F452_D0.6500.50
36_T135_A0.6480.50
46_V51_M0.6460.49
211_V431_L0.6460.49
258_D262_C0.6460.49
208_I235_A0.6450.49
14_S239_C0.6450.49
452_D530_E0.6440.49
394_N399_K0.6440.49
33_L268_A0.6440.49
373_N442_E0.6430.49
513_R516_R0.6430.49
320_F529_V0.6430.49
360_V389_I0.6420.49
100_K104_R0.6420.49
309_V421_Q0.6420.49
396_L474_E0.6410.49
493_I501_F0.6410.49
502_V520_L0.6400.49
84_N87_S0.6400.49
382_L386_V0.6400.49
302_L305_A0.6380.49
280_L515_T0.6370.49
388_S391_Y0.6370.49
170_V204_I0.6360.48
66_A93_K0.6350.48
153_P194_H0.6340.48
364_I394_N0.6300.48
60_F79_I0.6300.48
25_G139_I0.6290.48
427_L431_L0.6290.48
313_L350_I0.6280.48
36_T79_I0.6270.47
275_S278_K0.6270.47
63_D510_F0.6260.47
248_I255_Q0.6260.47
481_S495_L0.6260.47
7_V37_I0.6240.47
33_L267_L0.6210.47
240_E251_E0.6200.47
226_A232_D0.6200.47
280_L284_V0.6170.46
438_C492_I0.6170.46
24_L257_L0.6160.46
114_V153_P0.6150.46
357_D406_I0.6140.46
465_F492_I0.6140.46
106_D110_G0.6130.46
44_I328_W0.6130.46
129_A135_A0.6120.46
230_D235_A0.6100.46
364_I367_T0.6100.46
101_K121_E0.6100.46
370_A387_A0.6050.45
465_F490_V0.6050.45
396_L400_G0.6030.45
80_D515_T0.6030.45
391_Y396_L0.6010.45
380_I521_F0.6010.45
296_V366_A0.6000.45
418_L431_L0.6000.45
378_L504_S0.6000.45
506_F518_Q0.5990.44
440_L492_I0.5990.44
101_K124_D0.5990.44
360_V403_S0.5980.44
336_E368_K0.5980.44
247_S282_N0.5960.44
44_I114_V0.5960.44
125_R419_P0.5960.44
6_F158_I0.5950.44
428_G433_L0.5950.44
319_A522_K0.5950.44
185_G241_D0.5950.44
220_D223_D0.5940.44
398_L402_H0.5940.44
262_C267_L0.5930.44
449_V522_K0.5930.44
350_I504_S0.5920.44
33_L270_K0.5890.43
360_V402_H0.5890.43
99_L248_I0.5880.43
115_I347_D0.5880.43
149_I236_V0.5880.43
428_G464_E0.5870.43
35_V471_Q0.5870.43
390_E501_F0.5850.43
476_Q495_L0.5840.43
167_R232_D0.5840.43
115_I418_L0.5840.43
518_Q521_F0.5830.43
420_E427_L0.5820.43
283_K319_A0.5810.43
386_V406_I0.5810.43
500_W520_L0.5790.42
313_L326_V0.5790.42
303_P309_V0.5790.42
70_L111_T0.5790.42
384_M506_F0.5780.42
162_K205_Q0.5770.42
305_A386_V0.5770.42
442_E452_D0.5750.42
293_I380_I0.5740.42
194_H198_E0.5740.42
421_Q425_E0.5740.42
178_V211_V0.5730.42
40_F93_K0.5730.42
438_C489_L0.5730.42
365_V369_Y0.5720.42
38_Q74_H0.5710.41
232_D235_A0.5700.41
368_K390_E0.5700.41
402_H406_I0.5700.41
194_H197_K0.5680.41
384_M492_I0.5670.41
34_N270_K0.5670.41
262_C268_A0.5670.41
29_K82_N0.5670.41
24_L210_V0.5660.41
436_Y484_S0.5660.41
38_Q129_A0.5660.41
195_S199_L0.5650.41
12_V181_I0.5650.41
86_F93_K0.5640.41
66_A187_L0.5630.41
294_G370_A0.5630.41
502_V523_G0.5630.41
72_L93_K0.5620.41
208_I261_V0.5610.40
166_G389_I0.5600.40
317_G322_T0.5600.40
310_V314_R0.5600.40
123_K230_D0.5600.40
207_N263_E0.5590.40
126_V158_I0.5590.40
320_F522_K0.5590.40
329_I343_T0.5580.40
504_S510_F0.5580.40
40_F125_R0.5570.40
181_I238_E0.5570.40
293_I525_I0.5570.40
350_I525_I0.5570.40
33_L252_L0.5570.40
510_F514_P0.5570.40
137_V269_C0.5570.40
20_V326_V0.5570.40
244_N318_Y0.5560.40
96_S99_L0.5560.40
36_T52_S0.5560.40
481_S492_I0.5550.40
364_I368_K0.5550.40
29_K513_R0.5550.40
29_K307_I0.5540.40
201_S422_K0.5540.40
418_L511_K0.5530.40
483_T486_D0.5530.40
315_H512_S0.5520.39
14_S162_K0.5520.39
7_V23_S0.5510.39
229_C482_G0.5500.39
14_S189_T0.5500.39
446_A506_F0.5490.39
349_I369_Y0.5490.39
344_S530_E0.5480.39
55_Q59_V0.5480.39
402_H413_P0.5470.39
128_R266_K0.5470.39
110_G484_S0.5460.39
87_S129_A0.5450.39
465_F469_F0.5440.39
119_T228_F0.5440.39
441_E481_S0.5430.39
347_D531_A0.5430.39
314_R318_Y0.5430.39
418_L424_V0.5420.38
495_L499_P0.5410.38
165_I172_Y0.5410.38
119_T123_K0.5400.38
51_M55_Q0.5390.38
48_P140_T0.5390.38
274_M278_K0.5380.38
279_E282_N0.5380.38
205_Q230_D0.5370.38
88_N91_T0.5370.38
5_I60_F0.5360.38
309_V318_Y0.5360.38
2_T138_V0.5350.38
436_Y485_P0.5350.38
378_L503_A0.5340.38
128_R419_P0.5340.38
445_K496_K0.5340.38
302_L378_L0.5330.38
159_R177_L0.5310.37
62_T74_H0.5310.37
101_K125_R0.5310.37
20_V26_R0.5300.37
199_L204_I0.5290.37
55_Q352_P0.5290.37
438_C455_V0.5280.37
259_K262_C0.5280.37
280_L353_G0.5280.37
400_G472_Q0.5280.37
146_V242_A0.5280.37
211_V217_I0.5270.37
395_V473_M0.5270.37
446_A520_L0.5260.37
363_K455_V0.5260.37
15_L165_I0.5260.37
50_T429_G0.5260.37
178_V241_D0.5250.37
187_L213_T0.5240.37
334_V340_A0.5240.37
228_F236_V0.5230.37
446_A479_V0.5220.36
126_V138_V0.5210.36
372_E390_E0.5210.36
197_K205_Q0.5210.36
479_V495_L0.5210.36
175_C230_D0.5200.36
89_V94_I0.5200.36
350_I366_A0.5200.36
129_A134_N0.5200.36
253_Q274_M0.5190.36
82_N175_C0.5190.36
66_A177_L0.5190.36
37_I84_N0.5190.36
2_T135_A0.5180.36
89_V146_V0.5180.36
225_I238_E0.5180.36
110_G281_V0.5180.36
185_G302_L0.5180.36
259_K271_E0.5180.36
243_D394_N0.5170.36
275_S279_E0.5170.36
436_Y489_L0.5170.36
493_I504_S0.5160.36
182_K503_A0.5160.36
87_S307_I0.5150.36
368_K531_A0.5150.36
52_S506_F0.5150.36
229_C296_V0.5140.36
333_E337_N0.5140.36
439_K486_D0.5140.36
237_I256_G0.5140.36
162_K449_V0.5140.36
19_I295_L0.5140.36
72_L111_T0.5130.36
353_G406_I0.5130.36
428_G461_H0.5130.36
14_S258_D0.5120.35
28_L261_V0.5120.35
125_R162_K0.5120.35
344_S375_I0.5120.35
396_L496_K0.5120.35
48_P184_A0.5110.35
202_L226_A0.5110.35
34_N133_T0.5110.35
101_K183_A0.5110.35
74_H493_I0.5100.35
287_L318_Y0.5100.35
20_V307_I0.5100.35
242_A247_S0.5090.35
170_V302_L0.5080.35
495_L502_V0.5080.35
253_Q256_G0.5080.35
360_V495_L0.5080.35
173_I329_I0.5070.35
279_E399_K0.5070.35
148_D160_Q0.5070.35
211_V377_F0.5060.35
105_G148_D0.5060.35
93_K101_K0.5050.35
448_E451_Q0.5050.35
74_H180_Y0.5050.35
420_E440_L0.5050.35
513_R517_P0.5040.35
366_A390_E0.5040.35
498_H521_F0.5030.35
88_N101_K0.5030.35
442_E529_V0.5030.35
135_A209_I0.5030.35
8_T12_V0.5030.35
253_Q278_K0.5030.35
459_H464_E0.5020.34
25_G79_I0.5020.34
528_S531_A0.5020.34
335_T340_A0.5010.34
384_M503_A0.5000.34
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4zdjA 4 0.9813 100 0.387 Contact Map
3nvaA 2 0.9888 100 0.413 Contact Map
1vcoA 4 0.9813 100 0.443 Contact Map
2vo1A 4 0.4262 100 0.471 Contact Map
1s1mA 4 0.9794 100 0.507 Contact Map
2v4uA 1 0.4598 100 0.785 Contact Map
2w7tA 1 0.4542 100 0.81 Contact Map
1l9xA 1 0.4206 100 0.897 Contact Map
4l8fC 3 0.415 100 0.897 Contact Map
3uowA 2 0.3963 99.9 0.898 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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