GREMLIN Database
RS14 - 30S ribosomal protein S14
UniProt: P12878 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 61 (61)
Sequences: 1673 (499)
Seq/√Len: 63.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
8_A11_Q2.7271.00
22_T33_V2.7261.00
34_I44_F2.6901.00
24_C27_C2.4701.00
44_F56_V2.1351.00
25_E38_K2.1021.00
46_E50_K2.0431.00
27_C43_C2.0281.00
21_Y31_H1.9921.00
14_P20_E1.8151.00
53_I56_V1.8001.00
27_C40_C1.7170.99
10_Q14_P1.6900.99
4_K8_A1.5520.99
10_Q20_E1.5140.99
6_M9_K1.4580.98
4_K7_I1.4350.98
3_K6_M1.4210.98
48_A56_V1.3900.97
24_C43_C1.3810.97
11_Q14_P1.3780.97
10_Q21_Y1.2910.96
47_L52_Q1.2810.96
6_M30_P1.2770.96
31_H49_Y1.2570.95
40_C43_C1.2400.95
5_S8_A1.2010.94
13_T20_E1.1760.93
22_T35_R1.1420.92
39_L47_L1.1170.92
37_F56_V1.0930.91
10_Q13_T1.0500.89
26_R39_L1.0370.88
21_Y30_P0.9910.86
16_F40_C0.9840.85
26_R46_E0.9680.84
6_M21_Y0.9630.84
36_K53_I0.9210.81
13_T16_F0.8610.77
7_I11_Q0.8560.76
43_C46_E0.8470.76
16_F27_C0.8380.75
47_L50_K0.8320.74
22_T32_S0.7900.70
25_E39_L0.7860.70
49_Y52_Q0.7830.70
9_K12_R0.7470.66
48_A53_I0.7430.66
12_R16_F0.7270.64
54_P57_K0.6850.59
49_Y57_K0.6820.59
24_C40_C0.6760.58
49_Y53_I0.6640.57
26_R47_L0.6600.57
14_P17_K0.6590.56
34_I37_F0.6290.53
36_K51_G0.6270.53
19_Q32_S0.6260.53
33_V39_L0.6180.52
36_K44_F0.6120.51
15_K24_C0.6080.51
8_A12_R0.6060.50
27_C42_I0.6050.50
32_S35_R0.6010.50
44_F53_I0.5990.50
42_I49_Y0.5970.49
31_H36_K0.5960.49
25_E33_V0.5710.46
49_Y59_A0.5700.46
44_F48_A0.5640.45
23_R30_P0.5630.45
42_I46_E0.5620.45
38_K47_L0.5610.45
37_F44_F0.5590.45
6_M10_Q0.5540.44
21_Y32_S0.5490.44
40_C48_A0.5470.44
1_M4_K0.5440.43
9_K13_T0.5380.42
13_T27_C0.5360.42
8_A44_F0.5350.42
41_R58_K0.5270.41
29_R42_I0.5240.41
44_F49_Y0.5220.41
35_R44_F0.5210.41
30_P38_K0.5140.40
1_M5_S0.5130.40
48_A52_Q0.5070.39
17_K20_E0.5060.39
26_R30_P0.5030.39
2_A5_S0.5010.38
2_A7_I0.5000.38
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rb5N 1 0.9836 99.9 0.146 Contact Map
3bbnN 1 0.9836 99.9 0.192 Contact Map
4tp8N 1 0.9836 99.9 0.221 Contact Map
5aj3N 1 1 99.8 0.311 Contact Map
3j60d 1 0.7541 99.5 0.493 Contact Map
3j20P 1 0.8852 99.5 0.494 Contact Map
4w23d 1 0.8197 99.4 0.509 Contact Map
3j7aT 1 0.7541 99.4 0.517 Contact Map
3zey8 1 0.6557 99.3 0.529 Contact Map
4ujpe 1 0.8361 99.3 0.532 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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