GREMLIN Database
RS17 - 30S ribosomal protein S17
UniProt: P12874 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 87 (79)
Sequences: 2119 (996)
Seq/√Len: 112.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
47_K72_T4.4851.00
62_K79_E3.5711.00
26_V43_S3.1281.00
23_I77_L2.7201.00
20_D53_N2.1211.00
17_D56_K1.9841.00
64_M76_R1.8891.00
56_K83_E1.8701.00
55_A77_L1.7821.00
30_Y41_K1.7671.00
17_D57_I1.7551.00
46_F63_I1.6651.00
27_V46_F1.6531.00
54_Q83_E1.5671.00
7_R64_M1.5461.00
13_R60_I1.5181.00
66_T76_R1.4741.00
32_K37_G1.4041.00
28_E41_K1.3951.00
19_M47_K1.3921.00
55_A80_V1.3871.00
31_K42_Y1.3721.00
48_A63_I1.3471.00
24_T47_K1.3381.00
64_M78_V1.3261.00
23_I55_A1.3050.99
60_I82_E1.2760.99
54_Q80_V1.2740.99
30_Y39_R1.2330.99
15_V26_V1.2160.99
11_Q62_K1.1580.99
23_I48_A1.1380.99
21_K51_E1.1260.98
9_V62_K1.1150.98
8_K65_E1.0870.98
13_R26_V1.0310.97
11_Q60_I1.0210.97
32_K39_R1.0160.97
62_K81_V1.0070.97
50_D53_N1.0020.97
9_V64_M0.9880.96
48_A61_V0.9660.96
50_D55_A0.9650.96
69_L76_R0.9620.96
77_L80_V0.9610.96
22_T47_K0.9580.96
24_T45_K0.9530.96
10_Y75_F0.9520.96
29_T39_R0.9480.96
15_V45_K0.9240.95
68_P74_R0.9200.95
49_H73_K0.9130.95
25_V63_I0.8770.93
23_I61_V0.8530.92
48_A77_L0.8500.92
9_V78_V0.8490.92
16_S24_T0.8330.91
18_K57_I0.8170.91
26_V45_K0.8160.91
62_K78_V0.7910.89
69_L74_R0.7850.89
25_V61_V0.7750.88
10_Y63_I0.7740.88
13_R28_E0.7670.88
17_D23_I0.7660.88
31_K39_R0.7610.87
66_T69_L0.7600.87
38_K82_E0.7550.87
25_V48_A0.7490.86
33_H40_V0.7360.85
70_S73_K0.7190.84
8_K74_R0.7100.83
10_Y46_F0.7080.83
54_Q79_E0.7080.83
56_K84_A0.6920.82
21_K50_D0.6630.79
35_L39_R0.6580.78
17_D55_A0.6580.78
29_T44_K0.6440.77
49_H70_S0.6210.74
18_K24_T0.6120.73
10_Y29_T0.6090.73
19_M24_T0.6040.72
11_Q81_V0.5990.72
43_S80_V0.5980.72
24_T72_T0.5960.71
7_R65_E0.5930.71
51_E76_R0.5920.71
31_K84_A0.5890.70
24_T43_S0.5890.70
30_Y40_V0.5870.70
34_T39_R0.5830.70
8_K76_R0.5730.68
56_K59_D0.5710.68
31_K40_V0.5650.67
15_V24_T0.5650.67
22_T73_K0.5620.67
12_G58_G0.5600.67
29_T71_A0.5550.66
39_R44_K0.5530.66
13_R27_V0.5480.65
51_E67_R0.5400.64
20_D50_D0.5380.64
28_E43_S0.5370.63
39_R42_Y0.5360.63
7_R66_T0.5350.63
31_K35_L0.5330.63
33_H38_K0.5320.63
8_K32_K0.5160.60
60_I83_E0.5160.60
76_R84_A0.5110.60
13_R34_T0.5100.59
9_V71_A0.5100.59
51_E77_L0.5100.59
17_D53_N0.5020.58
41_K81_V0.5000.58
7_R76_R0.5000.58
30_Y42_Y0.5000.58
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1qd7I 1 0.9425 100 0.148 Contact Map
4tp8Q 1 0.9195 100 0.152 Contact Map
4rb5Q 1 0.9425 100 0.155 Contact Map
3bbnQ 1 0.931 100 0.17 Contact Map
3j20R 1 1 100 0.171 Contact Map
4bpeQ 1 1 100 0.174 Contact Map
3j7aV 1 0.977 100 0.182 Contact Map
5aj3Q 1 1 100 0.186 Contact Map
4ujpM 1 0.977 100 0.189 Contact Map
3j60L 1 0.6782 100 0.195 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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