GREMLIN Database
PUR9 - Bifunctional purine biosynthesis protein PurH
UniProt: P12048 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 512 (504)
Sequences: 2868 (1446)
Seq/√Len: 64.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
489_E493_K5.2761.00
392_K496_D5.2561.00
393_R399_E4.0671.00
312_E333_S3.7951.00
24_T46_D3.7661.00
150_D175_K3.7461.00
22_E155_L3.6751.00
465_P469_E3.5931.00
312_E335_S3.5361.00
209_K212_S3.3431.00
240_E352_T3.2751.00
5_R29_E3.2711.00
77_A88_I3.2541.00
320_A323_N3.1241.00
315_K341_V3.1151.00
8_I30_V3.0811.00
157_Q168_K3.0661.00
116_T119_E3.0641.00
132_L176_V2.9301.00
333_S352_T2.8231.00
334_F350_L2.7711.00
30_V45_V2.7471.00
75_L99_V2.6311.00
315_K337_E2.6261.00
269_A283_T2.6031.00
281_V409_V2.5821.00
468_V479_I2.5481.00
26_L159_K2.4961.00
314_D317_T2.4401.00
147_D175_K2.3681.00
38_K42_E2.3491.00
132_L144_V2.3181.00
315_K319_E2.3171.00
143_T164_V2.3051.00
78_V81_N2.3051.00
469_E497_E2.2441.00
270_A309_L2.2411.00
481_Q502_M2.2221.00
86_A90_E2.2201.00
8_I20_V2.1911.00
157_Q165_S2.1881.00
380_H507_I2.1881.00
406_A421_A2.1361.00
211_Q246_E2.1281.00
441_K445_E2.0991.00
286_T289_E2.0951.00
465_P490_D2.0631.00
252_I368_V2.0471.00
60_M88_I2.0141.00
431_A434_M2.0111.00
22_E159_K1.9711.00
18_P21_K1.9641.00
39_L43_N1.9521.00
79_R97_D1.9311.00
50_I71_I1.9221.00
145_I154_V1.9211.00
207_F372_L1.9151.00
110_I120_A1.9141.00
78_V84_H1.9101.00
420_L444_I1.8921.00
396_N399_E1.8701.00
487_R490_D1.8461.00
117_Y139_H1.8311.00
53_V71_I1.8291.00
153_P171_E1.8261.00
31_I53_V1.8231.00
435_N446_Q1.8211.00
80_G85_M1.8121.00
440_A467_T1.8071.00
493_K497_E1.7971.00
402_D421_A1.7861.00
3_I28_V1.7851.00
309_L313_V1.7781.00
493_K496_D1.7411.00
456_L471_A1.7411.00
288_A292_D1.7360.99
465_P497_E1.7360.99
37_K47_V1.7300.99
339_L343_T1.7120.99
321_L326_L1.7080.99
336_Q340_D1.7030.99
287_I309_L1.6980.99
402_D422_K1.6870.99
210_K227_Q1.6860.99
399_E477_T1.6780.99
37_K41_Q1.6730.99
307_I321_L1.6710.99
19_F145_I1.6680.99
253_K276_M1.6640.99
469_E473_K1.6590.99
19_F154_V1.6560.99
107_K186_L1.6500.99
59_I91_H1.6410.99
455_A478_A1.6360.99
285_K289_E1.6340.99
19_F100_V1.6320.99
73_G93_I1.6260.99
420_L427_V1.6160.99
292_D320_A1.6150.99
284_G293_R1.6020.99
243_H348_L1.5710.99
41_Q49_G1.5670.99
391_T502_M1.5530.99
253_K366_T1.5450.99
249_Y364_Q1.5410.99
147_D150_D1.5320.99
117_Y191_L1.5300.99
26_L158_I1.5270.99
268_P287_I1.5200.99
383_D386_E1.5130.99
494_K497_E1.5080.99
117_Y170_R1.4990.98
438_G446_Q1.4940.98
454_S476_V1.4780.98
284_G289_E1.4760.98
82_E86_A1.4740.98
469_E498_Y1.4670.98
243_H343_T1.4550.98
60_M87_Q1.4430.98
242_L352_T1.4410.98
387_I404_K1.4370.98
494_K498_Y1.4340.98
322_H344_A1.4200.98
255_A328_I1.4170.98
264_E412_H1.4000.98
29_E48_I1.3950.98
132_L146_V1.3850.97
112_K115_V1.3570.97
393_R477_T1.3530.97
225_F368_V1.3480.97
115_V120_A1.3410.97
59_I134_A1.3380.97
243_H342_L1.3330.97
465_P498_Y1.3310.97
272_A302_I1.3290.97
152_S156_N1.3270.97
37_K49_G1.3240.97
402_D423_D1.3200.97
17_V39_L1.3180.97
222_E376_D1.3170.97
403_L478_A1.3130.96
398_Q402_D1.3130.96
307_I326_L1.3120.96
398_Q423_D1.3120.96
29_E94_Q1.3120.96
146_V179_H1.3120.96
479_I500_I1.3090.96
247_L252_I1.3080.96
470_E473_K1.3080.96
31_I96_I1.3040.96
3_I98_L1.3030.96
402_D424_N1.3030.96
456_L476_V1.3010.96
387_I480_I1.3000.96
468_V491_S1.2980.96
20_V40_L1.2970.96
99_V130_G1.2950.96
384_D404_K1.2880.96
61_D84_H1.2860.96
264_E411_K1.2760.96
144_V176_V1.2680.96
363_K376_D1.2660.96
178_R192_T1.2580.96
388_S506_G1.2570.96
22_E26_L1.2560.95
31_I50_I1.2520.95
80_G140_Q1.2470.95
401_E424_N1.2360.95
174_A178_R1.2340.95
365_L372_L1.2330.95
289_E293_R1.2250.95
79_R141_D1.2190.95
61_D81_N1.2150.95
78_V141_D1.2130.95
313_V334_F1.2070.94
25_E159_K1.2050.94
452_K477_T1.1980.94
259_V353_L1.1910.94
174_A191_L1.1850.94
465_P494_K1.1750.94
157_Q164_V1.1670.93
8_I16_L1.1610.93
130_G135_A1.1560.93
444_I474_A1.1520.93
107_K179_H1.1500.93
112_K119_E1.1480.93
21_K25_E1.1480.93
166_L170_R1.1460.93
156_N159_K1.1450.93
168_K172_L1.1300.92
73_G91_H1.1290.92
11_S105_P1.1250.92
448_G451_A1.1250.92
82_E85_M1.1230.92
17_V43_N1.1220.92
139_H170_R1.1220.92
28_V98_L1.1150.92
339_L350_L1.1140.92
116_T120_A1.1100.91
277_N431_A1.1070.91
225_F237_A1.1050.91
473_K498_Y1.1020.91
11_S123_N1.1020.91
22_E25_E1.1000.91
117_Y120_A1.0990.91
21_K45_V1.0970.91
70_N92_G1.0970.91
256_D260_Q1.0890.91
420_L454_S1.0880.91
143_T172_L1.0830.90
154_V168_K1.0800.90
198_K222_E1.0790.90
53_V70_N1.0770.90
337_E340_D1.0760.90
420_L476_V1.0750.90
397_E401_E1.0740.90
470_E474_A1.0720.90
157_Q162_G1.0620.90
288_A320_A1.0600.89
384_D400_W1.0580.89
427_V451_A1.0540.89
199_E222_E1.0530.89
130_G134_A1.0520.89
262_V308_A1.0520.89
297_A426_T1.0510.89
5_R31_I1.0500.89
330_I353_L1.0440.89
243_H350_L1.0430.89
12_D108_E1.0430.89
472_A500_I1.0380.88
319_E323_N1.0380.88
399_E501_A1.0310.88
189_D193_N1.0280.88
378_D509_H1.0250.88
486_I489_E1.0240.88
288_A316_A1.0240.88
468_V495_A1.0200.88
389_I395_P1.0180.87
317_T321_L1.0140.87
14_T149_A1.0120.87
241_Q246_E1.0100.87
143_T157_Q1.0090.87
107_K111_S0.9990.86
315_K335_S0.9930.86
200_P224_T0.9860.86
18_P152_S0.9850.86
86_A89_N0.9840.86
434_M442_I0.9840.86
153_P168_K0.9820.86
87_Q90_E0.9810.85
295_F299_K0.9780.85
389_I503_V0.9780.85
334_F352_T0.9760.85
316_A319_E0.9760.85
80_G141_D0.9740.85
236_I239_A0.9690.85
296_E425_M0.9680.85
287_I317_T0.9670.85
107_K182_A0.9650.85
492_I504_F0.9630.84
59_I93_I0.9620.84
292_D296_E0.9590.84
22_E158_I0.9580.84
146_V150_D0.9560.84
131_M134_A0.9560.84
77_A95_P0.9520.84
265_F269_A0.9520.84
259_V263_R0.9460.83
303_F486_I0.9450.83
297_A425_M0.9390.83
199_E224_T0.9380.83
72_H134_A0.9370.83
426_T429_V0.9370.83
382_F387_I0.9340.83
261_I271_V0.9330.82
75_L131_M0.9330.82
174_A192_T0.9310.82
438_G441_K0.9300.82
77_A85_M0.9300.82
431_A442_I0.9290.82
139_H173_A0.9280.82
88_I95_P0.9260.82
478_A501_A0.9250.82
395_P399_E0.9230.82
185_A206_T0.9230.82
387_I400_W0.9200.82
255_A330_I0.9200.82
395_P503_V0.9200.82
154_V172_L0.9190.81
239_A351_L0.9160.81
309_L317_T0.9150.81
311_R332_P0.9140.81
469_E494_K0.9140.81
150_D153_P0.9140.81
15_N18_P0.9120.81
437_V467_T0.9120.81
48_I53_V0.9100.81
287_I311_R0.9060.81
490_D493_K0.9060.81
389_I394_E0.9050.80
404_K480_I0.9040.80
401_E404_K0.8990.80
286_T316_A0.8980.80
262_V269_A0.8970.80
55_G70_N0.8950.80
16_L20_V0.8920.80
295_F324_I0.8920.80
140_Q166_L0.8900.79
108_E112_K0.8900.79
418_I459_D0.8890.79
99_V144_V0.8880.79
107_K208_E0.8880.79
319_E344_A0.8870.79
273_V308_A0.8860.79
413_V419_V0.8840.79
321_L329_I0.8780.78
390_P504_F0.8770.78
419_V426_T0.8740.78
393_R499_G0.8740.78
395_P501_A0.8730.78
24_T30_V0.8720.78
362_E377_L0.8720.78
60_M78_V0.8690.78
342_L350_L0.8680.78
468_V472_A0.8620.77
168_K171_E0.8610.77
81_N84_H0.8600.77
114_D119_E0.8600.77
158_I163_S0.8600.77
300_T438_G0.8590.77
393_R501_A0.8580.77
155_L159_K0.8580.77
322_H348_L0.8570.77
309_L321_L0.8570.77
270_A321_L0.8560.77
291_F324_I0.8550.77
139_H166_L0.8540.76
255_A351_L0.8500.76
165_S168_K0.8500.76
164_V169_K0.8460.76
420_L456_L0.8450.76
170_R194_V0.8450.76
30_V48_I0.8450.76
314_D335_S0.8420.75
468_V476_V0.8380.75
283_T424_N0.8350.75
406_A455_A0.8340.75
333_S354_D0.8310.75
85_M88_I0.8300.74
467_T491_S0.8280.74
287_I314_D0.8270.74
434_M438_G0.8270.74
59_I73_G0.8260.74
178_R182_A0.8240.74
61_D87_Q0.8240.74
292_D323_N0.8210.74
41_Q46_D0.8210.74
120_A190_Y0.8200.74
56_F91_H0.8180.73
39_L42_E0.8140.73
300_T435_N0.8130.73
178_R188_A0.8110.73
343_T348_L0.8080.72
257_A276_M0.8070.72
75_L132_L0.8050.72
267_E311_R0.8050.72
388_S489_E0.8050.72
472_A498_Y0.8010.72
209_K224_T0.7990.72
60_M73_G0.7980.71
481_Q504_F0.7980.71
477_T499_G0.7960.71
270_A307_I0.7930.71
319_E322_H0.7920.71
143_T154_V0.7920.71
337_E341_V0.7920.71
268_P311_R0.7870.70
8_I17_V0.7810.70
225_F252_I0.7800.70
363_K374_I0.7790.70
19_F155_L0.7760.69
75_L144_V0.7750.69
208_E227_Q0.7740.69
383_D404_K0.7730.69
456_L468_V0.7710.69
109_T120_A0.7700.69
289_E292_D0.7690.69
85_M141_D0.7670.68
109_T115_V0.7640.68
164_V168_K0.7640.68
441_K470_E0.7640.68
205_V372_L0.7630.68
72_H130_G0.7600.68
316_A335_S0.7590.68
261_I409_V0.7540.67
72_H131_M0.7520.67
465_P491_S0.7510.67
434_M446_Q0.7510.67
451_A454_S0.7500.67
240_E333_S0.7500.67
265_F409_V0.7490.67
245_K327_E0.7480.67
420_L440_A0.7480.67
17_V21_K0.7460.66
109_T123_N0.7440.66
269_A281_V0.7410.66
83_E87_Q0.7400.66
440_A456_L0.7400.66
153_P157_Q0.7380.65
448_G474_A0.7380.65
117_Y194_V0.7370.65
109_T112_K0.7360.65
257_A277_N0.7350.65
148_P151_Y0.7340.65
182_A186_L0.7340.65
49_G52_E0.7330.65
276_M366_T0.7300.65
192_T202_Q0.7290.65
391_T481_Q0.7280.64
84_H87_Q0.7280.64
277_N434_M0.7260.64
16_L39_L0.7250.64
73_G96_I0.7230.64
85_M89_N0.7230.64
489_E497_E0.7230.64
440_A468_V0.7230.64
28_V158_I0.7220.64
167_Q170_R0.7220.64
24_T40_L0.7220.64
59_I87_Q0.7210.64
228_T367_S0.7200.64
153_P156_N0.7180.63
388_S394_E0.7170.63
11_S179_H0.7140.63
181_A188_A0.7120.63
300_T441_K0.7100.62
435_N438_G0.7100.62
135_A142_V0.7070.62
272_A295_F0.7060.62
255_A308_A0.7060.62
489_E496_D0.7060.62
114_D120_A0.7050.62
438_G449_E0.7030.62
334_F351_L0.7020.62
73_G88_I0.7010.61
287_I313_V0.7010.61
334_F339_L0.7000.61
429_V434_M0.6990.61
121_I140_Q0.6990.61
108_E111_S0.6960.61
300_T449_E0.6950.61
267_E283_T0.6950.61
276_M328_I0.6950.61
209_K226_Y0.6920.60
38_K41_Q0.6920.60
282_G302_I0.6890.60
112_K123_N0.6870.60
364_Q367_S0.6840.60
250_N327_E0.6840.60
434_M439_S0.6830.59
132_L143_T0.6830.59
329_I342_L0.6820.59
438_G467_T0.6820.59
439_S442_I0.6820.59
185_A204_T0.6800.59
425_M450_K0.6790.59
110_I190_Y0.6790.59
390_P492_I0.6780.59
202_Q206_T0.6780.59
64_L69_P0.6770.59
285_K311_R0.6760.59
340_D343_T0.6760.59
154_V164_V0.6760.59
154_V158_I0.6760.59
444_I467_T0.6750.59
111_S186_L0.6750.59
382_F507_I0.6750.59
284_G425_M0.6720.58
236_I255_A0.6720.58
406_A457_G0.6720.58
380_H386_E0.6710.58
291_F320_A0.6700.58
119_E123_N0.6690.58
60_M84_H0.6680.58
83_E86_A0.6670.58
8_I100_V0.6660.58
178_R202_Q0.6650.57
89_N94_Q0.6650.57
326_L348_L0.6640.57
329_I348_L0.6640.57
5_R28_V0.6640.57
420_L451_A0.6630.57
339_L352_T0.6620.57
88_I92_G0.6620.57
344_A348_L0.6610.57
56_F87_Q0.6610.57
213_L252_I0.6600.57
75_L176_V0.6580.57
16_L30_V0.6570.57
235_S239_A0.6570.57
465_P487_R0.6570.57
420_L435_N0.6560.56
3_I158_I0.6550.56
259_V356_S0.6540.56
269_A284_G0.6530.56
400_W480_I0.6530.56
11_S108_E0.6510.56
30_V246_E0.6510.56
271_V281_V0.6500.56
272_A414_K0.6470.55
400_W404_K0.6460.55
472_A494_K0.6450.55
322_H341_V0.6440.55
413_V434_M0.6430.55
272_A282_G0.6420.55
398_Q401_E0.6420.55
303_F323_N0.6390.54
50_I75_L0.6390.54
339_L342_L0.6360.54
174_A195_V0.6360.54
253_K256_D0.6330.54
302_I326_L0.6320.54
140_Q170_R0.6310.54
259_V354_D0.6310.54
4_K28_V0.6310.54
256_D371_G0.6300.53
121_I134_A0.6300.53
82_E89_N0.6300.53
421_A455_A0.6300.53
438_G444_I0.6290.53
20_V45_V0.6290.53
265_F268_P0.6270.53
115_V190_Y0.6260.53
270_A291_F0.6250.53
305_G326_L0.6240.53
235_S369_Q0.6240.53
266_T311_R0.6240.53
376_D379_M0.6230.53
438_G442_I0.6230.53
472_A497_E0.6230.53
405_L421_A0.6210.52
447_A451_A0.6200.52
196_G199_E0.6190.52
41_Q52_E0.6190.52
336_Q339_L0.6190.52
17_V42_E0.6180.52
31_I48_I0.6180.52
313_V317_T0.6170.52
384_D401_E0.6170.52
85_M95_P0.6170.52
79_R85_M0.6160.52
110_I115_V0.6140.52
448_G454_S0.6130.51
8_I45_V0.6130.51
284_G317_T0.6110.51
392_K499_G0.6100.51
75_L136_S0.6090.51
57_P91_H0.6090.51
60_M81_N0.6090.51
201_E208_E0.6080.51
81_N85_M0.6080.51
239_A255_A0.6060.51
109_T114_D0.6060.51
112_K120_A0.6060.51
67_L72_H0.6040.50
71_I134_A0.6040.50
14_T148_P0.6040.50
60_M77_A0.6030.50
59_I79_R0.6020.50
445_E449_E0.6020.50
191_L195_V0.6020.50
203_F207_F0.6020.50
491_S495_A0.6020.50
471_A476_V0.6010.50
431_A446_Q0.6000.50
81_N141_D0.6000.50
502_M505_T0.6000.50
346_K486_I0.5990.50
110_I116_T0.5980.50
313_V321_L0.5960.49
158_I161_E0.5960.49
291_F326_L0.5940.49
469_E490_D0.5940.49
253_K302_I0.5920.49
130_G170_R0.5910.49
384_D387_I0.5900.49
456_L479_I0.5900.49
282_G402_D0.5900.49
240_E339_L0.5890.49
265_F408_K0.5880.49
393_R496_D0.5860.48
402_D455_A0.5840.48
5_R94_Q0.5840.48
73_G134_A0.5840.48
259_V369_Q0.5840.48
16_L45_V0.5830.48
98_L143_T0.5830.48
48_I52_E0.5820.48
170_R174_A0.5820.48
199_E209_K0.5810.48
403_L503_V0.5790.48
236_I252_I0.5780.47
105_P108_E0.5770.47
261_I281_V0.5770.47
49_G53_V0.5740.47
422_K477_T0.5740.47
421_A424_N0.5740.47
297_A438_G0.5710.47
413_V429_V0.5700.46
84_H438_G0.5700.46
258_A308_A0.5690.46
261_I511_K0.5680.46
40_L45_V0.5670.46
446_Q467_T0.5660.46
479_I491_S0.5660.46
53_V94_Q0.5660.46
50_I134_A0.5650.46
249_Y367_S0.5650.46
192_T255_A0.5630.46
171_E174_A0.5630.46
427_V450_K0.5630.46
207_F228_T0.5610.45
243_H339_L0.5590.45
225_F247_L0.5590.45
234_G259_V0.5580.45
20_V24_T0.5580.45
364_Q377_L0.5580.45
382_F404_K0.5570.45
303_F462_F0.5560.45
117_Y476_V0.5560.45
462_F467_T0.5560.45
468_V500_I0.5550.45
69_P73_G0.5540.45
227_Q238_Q0.5530.44
143_T168_K0.5520.44
421_A457_G0.5520.44
40_L43_N0.5520.44
255_A259_V0.5510.44
455_A501_A0.5510.44
295_F320_A0.5510.44
272_A328_I0.5500.44
291_F321_L0.5500.44
293_R424_N0.5490.44
276_M464_M0.5490.44
30_V43_N0.5480.44
295_F302_I0.5480.44
238_Q354_D0.5470.44
288_A314_D0.5470.44
217_E250_N0.5470.44
62_G65_K0.5460.44
268_P310_N0.5460.44
115_V119_E0.5440.43
444_I470_E0.5440.43
102_N148_P0.5440.43
203_F374_I0.5430.43
220_H378_D0.5430.43
291_F295_F0.5420.43
319_E341_V0.5410.43
465_P493_K0.5410.43
61_D78_V0.5400.43
140_Q169_K0.5390.43
79_R96_I0.5380.43
5_R53_V0.5380.43
150_D429_V0.5380.43
207_F365_L0.5370.43
143_T169_K0.5360.43
433_Q459_D0.5360.43
41_Q47_V0.5360.43
262_V273_V0.5350.42
293_R423_D0.5350.42
409_V426_T0.5350.42
234_G238_Q0.5340.42
314_D337_E0.5340.42
448_G452_K0.5340.42
211_Q247_L0.5340.42
117_Y190_Y0.5330.42
261_I264_E0.5330.42
261_I412_H0.5320.42
389_I400_W0.5320.42
100_V234_G0.5320.42
178_R206_T0.5310.42
243_H322_H0.5310.42
178_R191_L0.5310.42
413_V417_A0.5310.42
143_T162_G0.5300.42
451_A474_A0.5300.42
288_A317_T0.5300.42
272_A326_L0.5300.42
41_Q213_L0.5290.42
456_L491_S0.5280.42
249_Y374_I0.5280.42
240_E354_D0.5280.42
38_K49_G0.5270.42
433_Q442_I0.5260.41
318_A341_V0.5260.41
456_L467_T0.5260.41
281_V426_T0.5260.41
178_R201_E0.5250.41
419_V431_A0.5250.41
100_V151_Y0.5250.41
409_V434_M0.5250.41
23_L28_V0.5240.41
391_T496_D0.5240.41
401_E423_D0.5230.41
365_L374_I0.5230.41
438_G470_E0.5220.41
31_I94_Q0.5220.41
268_P317_T0.5210.41
395_P496_D0.5210.41
33_T225_F0.5200.41
270_A405_L0.5200.41
236_I330_I0.5190.41
407_W505_T0.5190.41
75_L134_A0.5180.41
368_V371_G0.5180.41
182_A204_T0.5170.40
419_V429_V0.5170.40
77_A130_G0.5160.40
10_V151_Y0.5160.40
191_L212_S0.5150.40
295_F300_T0.5140.40
253_K272_A0.5140.40
100_V145_I0.5140.40
32_S35_G0.5140.40
467_T495_A0.5130.40
222_E386_E0.5130.40
103_L132_L0.5130.40
239_A271_V0.5130.40
188_A202_Q0.5120.40
417_A459_D0.5110.40
307_I324_I0.5110.40
353_L356_S0.5100.40
384_D397_E0.5090.40
428_G434_M0.5090.40
64_L67_L0.5080.39
75_L93_I0.5080.39
343_T350_L0.5080.39
32_S129_P0.5080.39
30_V47_V0.5070.39
265_F310_N0.5070.39
110_I186_L0.5070.39
265_F281_V0.5070.39
50_I130_G0.5060.39
11_S39_L0.5060.39
75_L130_G0.5060.39
211_Q252_I0.5050.39
109_T257_A0.5040.39
286_T314_D0.5040.39
403_L455_A0.5040.39
17_V40_L0.5030.39
17_V45_V0.5030.39
34_G129_P0.5030.39
322_H342_L0.5020.39
444_I454_S0.5020.39
281_V297_A0.5020.39
394_E400_W0.5000.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ehiA 2 0.9648 100 0.078 Contact Map
3zzmA 2 0.9902 100 0.079 Contact Map
1g8mA 2 0.9668 100 0.126 Contact Map
1zczA 2 0.8848 100 0.134 Contact Map
4j6eA 2 0.4258 100 0.842 Contact Map
2yvqA 2 0.2246 99.3 0.94 Contact Map
1a9xA 3 0.2559 99.2 0.942 Contact Map
2xw6A 5 0.2402 98.7 0.953 Contact Map
1b93A 5 0.2617 98.5 0.955 Contact Map
1vmdA 5 0.2773 98.4 0.957 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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