GREMLIN Database
PURL - Phosphoribosylformylglycinamidine synthase subunit PurL
UniProt: P12042 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 742 (710)
Sequences: 3274 (1661)
Seq/√Len: 62.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
356_M368_E4.6301.00
646_I660_V4.6251.00
295_E350_H4.4261.00
109_Y160_G4.3901.00
573_F580_V4.3301.00
656_L702_V3.9701.00
488_I493_A3.8991.00
637_V678_V3.5991.00
707_I720_H3.5861.00
365_V368_E3.5441.00
297_N300_L3.4661.00
645_A678_V3.4571.00
295_E360_T3.2711.00
335_I339_D3.2091.00
283_S348_V3.1351.00
217_K344_E3.0811.00
332_Q336_D2.9171.00
570_T574_K2.8481.00
332_Q335_I2.8341.00
581_Y698_H2.8341.00
523_I556_I2.8211.00
360_T365_V2.8031.00
682_K685_H2.7871.00
658_A708_L2.7751.00
414_L420_I2.7611.00
581_Y690_E2.7601.00
625_A689_F2.7531.00
406_D409_E2.7441.00
475_V478_K2.7081.00
412_K729_V2.7041.00
417_Q594_E2.6641.00
174_V426_V2.6201.00
226_A276_A2.5811.00
659_N709_A2.5791.00
659_N701_E2.5341.00
581_Y689_F2.5291.00
569_T626_I2.5231.00
440_V570_T2.4971.00
299_D362_K2.4701.00
474_E525_E2.4331.00
580_V658_A2.4071.00
212_M326_I2.4021.00
516_I541_L2.3991.00
679_V689_F2.3981.00
330_R333_E2.3961.00
479_I674_Q2.3921.00
621_A693_V2.3831.00
633_S649_S2.3571.00
647_A708_L2.3431.00
14_E18_Y2.3321.00
411_L643_G2.3301.00
170_V447_G2.2911.00
409_E413_A2.2841.00
333_E336_D2.2661.00
457_A565_T2.2261.00
302_P346_V2.2171.00
484_A556_I2.1641.00
210_T347_S2.1601.00
387_E518_K2.1421.00
484_A558_M2.1381.00
622_L679_V2.1081.00
310_A361_H2.0981.00
165_I256_L2.0821.00
578_D702_V2.0601.00
504_F519_A2.0571.00
573_F658_A2.0541.00
424_E731_K2.0461.00
581_Y696_A2.0341.00
693_V696_A2.0331.00
581_Y686_Q2.0251.00
133_V190_C2.0241.00
579_L698_H2.0241.00
578_D680_S2.0181.00
477_G519_A2.0141.00
633_S680_S2.0111.00
447_G450_R1.9991.00
445_D449_L1.9981.00
445_D635_H1.9961.00
408_N725_E1.9891.00
412_K725_E1.9891.00
408_N412_K1.9491.00
646_I678_V1.9421.00
303_Q313_M1.9411.00
386_Q511_E1.9361.00
129_R257_E1.9231.00
335_I345_A1.9171.00
642_L678_V1.9171.00
449_L452_R1.9001.00
469_L519_A1.8921.00
27_E58_K1.8911.00
261_E340_K1.8901.00
91_Q195_N1.8841.00
93_V458_L1.8831.00
518_K521_D1.8761.00
468_Y479_I1.8681.00
646_I658_A1.8651.00
75_L92_A1.8621.00
624_D628_K1.8461.00
358_R365_V1.8391.00
622_L631_V1.8381.00
385_S517_E1.8201.00
578_D632_Q1.8201.00
187_N555_V1.8191.00
31_I47_F1.8131.00
295_E358_R1.8051.00
331_E347_S1.8021.00
655_N727_E1.7911.00
131_I449_L1.7851.00
649_S680_S1.7841.00
632_Q682_K1.7691.00
681_V689_F1.7630.99
455_K566_A1.7580.99
120_I165_I1.7560.99
686_Q698_H1.7540.99
297_N360_T1.7440.99
489_I623_L1.7410.99
447_G452_R1.7200.99
685_H688_A1.7200.99
650_V658_A1.7150.99
411_L647_A1.7040.99
177_D603_I1.6960.99
575_Q578_D1.6910.99
299_D361_H1.6880.99
224_H227_T1.6770.99
647_A651_M1.6720.99
567_H627_K1.6650.99
709_A720_H1.6580.99
210_T331_E1.6570.99
455_K564_D1.6510.99
579_L686_Q1.6370.99
576_A704_A1.6320.99
512_I549_A1.6240.99
635_H648_E1.6230.99
210_T350_H1.6210.99
120_I190_C1.6190.99
727_E731_K1.6190.99
616_L620_K1.6090.99
732_G736_C1.6090.99
728_R732_G1.6090.99
446_A449_L1.6060.99
580_V680_S1.6050.99
445_D450_R1.6000.99
618_R677_F1.5960.99
567_H629_G1.5930.99
141_E178_S1.5850.99
632_Q680_S1.5780.99
73_R494_E1.5710.99
721_A726_L1.5700.99
659_N703_T1.5680.99
482_A674_Q1.5650.99
210_T326_I1.5570.99
626_I631_V1.5540.99
66_K521_D1.5530.99
445_D448_V1.5520.99
412_K721_A1.5470.99
179_S551_Y1.5310.99
135_N158_I1.5170.98
524_S528_N1.5020.98
651_M730_W1.5000.98
690_E696_A1.4980.98
419_T594_E1.4920.98
643_G710_I1.4770.98
62_P382_H1.4740.98
355_K372_D1.4720.98
562_I568_I1.4580.98
631_V679_V1.4560.98
564_D567_H1.4520.98
722_Q725_E1.4500.98
228_F233_M1.4490.98
420_I644_V1.4470.98
173_E423_K1.4450.98
573_F649_S1.4420.98
347_S350_H1.4390.98
416_Q732_G1.4360.98
650_V708_L1.4330.98
416_Q729_V1.4310.98
581_Y679_V1.4270.98
24_S381_Y1.4210.98
66_K524_S1.4130.98
411_L644_V1.4050.97
417_Q598_M1.4020.97
422_S731_K1.3990.97
210_T328_R1.3980.97
412_K726_L1.3870.97
81_G90_N1.3860.97
427_Y443_G1.3750.97
488_I498_V1.3720.97
35_L370_P1.3690.97
313_M361_H1.3680.97
293_G355_K1.3680.97
630_F685_H1.3640.97
472_D606_K1.3580.97
336_D339_D1.3560.97
631_V634_A1.3540.97
481_V523_I1.3510.97
265_C333_E1.3510.97
134_L460_M1.3500.97
474_E518_K1.3470.97
212_M335_I1.3410.97
531_S616_L1.3410.97
471_L607_A1.3360.97
583_I679_V1.3340.96
505_G515_Q1.3310.96
354_D358_R1.3270.96
686_Q690_E1.3270.96
721_A725_E1.3220.96
358_R368_E1.3060.96
634_A677_F1.3050.96
71_G85_V1.3040.96
207_V353_D1.3020.96
274_M282_S1.3010.96
105_A233_M1.2980.96
92_A196_H1.2970.96
589_E673_S1.2960.96
625_A631_V1.2940.96
90_N196_H1.2880.96
187_N462_T1.2870.96
450_R565_T1.2810.96
45_G311_Y1.2720.95
262_V334_I1.2710.95
424_E428_D1.2680.95
15_E19_Q1.2680.95
445_D452_R1.2640.95
85_V497_A1.2620.95
696_A699_I1.2600.95
468_Y674_Q1.2570.95
525_E529_V1.2560.95
326_I331_E1.2520.95
448_V568_I1.2500.95
213_Y274_M1.2500.95
89_D456_K1.2440.95
579_L582_V1.2420.95
583_I618_R1.2400.95
297_N362_K1.2400.95
408_N721_A1.2380.95
637_V645_A1.2300.94
472_D607_A1.2290.94
405_E410_M1.2290.94
33_S36_G1.2260.94
444_S449_L1.2250.94
288_S375_A1.2220.94
444_S447_G1.2220.94
581_Y681_V1.2120.94
371_V375_A1.2100.94
490_C634_A1.2090.94
628_K688_A1.2080.94
386_Q510_P1.2060.94
621_A692_T1.2020.94
483_E638_S1.2010.94
487_N636_D1.1980.94
643_G647_A1.1890.93
214_V338_F1.1880.93
310_A366_V1.1850.93
267_A330_R1.1830.93
211_V325_V1.1830.93
327_E330_R1.1830.93
490_C677_F1.1810.93
13_K17_L1.1800.93
494_E627_K1.1800.93
625_A692_T1.1770.93
586_T673_S1.1760.93
459_A488_I1.1730.93
636_D648_E1.1730.93
619_Q677_F1.1710.93
472_D518_K1.1700.93
646_I699_I1.1680.93
209_N269_V1.1660.93
659_N711_Q1.1660.93
220_R312_E1.1640.93
582_V637_V1.1620.93
74_V78_P1.1590.92
473_P515_Q1.1580.92
485_A532_T1.1560.92
269_V327_E1.1550.92
579_L701_E1.1520.92
644_V648_E1.1490.92
187_N499_T1.1470.92
588_P671_S1.1450.92
497_A533_P1.1430.92
47_F373_A1.1420.92
144_S181_E1.1420.92
211_V294_I1.1420.92
499_T557_G1.1410.92
471_L605_G1.1380.92
498_V534_V1.1370.92
529_V613_D1.1350.92
68_P74_V1.1340.92
692_T695_D1.1320.92
359_L367_C1.1280.91
575_Q682_K1.1260.91
574_K680_S1.1230.91
444_S450_R1.1210.91
622_L677_F1.1180.91
579_L683_K1.1150.91
209_N351_V1.1140.91
630_F688_A1.1140.91
25_D29_A1.1130.91
177_D470_Y1.1120.91
688_A691_A1.1120.91
446_A452_R1.1100.91
352_T355_K1.1090.91
448_V452_R1.1050.91
153_E156_A1.1050.91
573_F680_S1.1040.91
472_D475_V1.1010.90
415_L647_A1.0990.90
97_I462_T1.0930.90
459_A493_A1.0910.90
446_A491_S1.0830.90
446_A450_R1.0820.90
577_G702_V1.0770.89
563_E627_K1.0770.89
572_H654_E1.0770.89
425_W429_Q1.0750.89
195_N198_D1.0740.89
483_E636_D1.0730.89
639_E648_E1.0730.89
97_I555_V1.0690.89
189_M557_G1.0640.89
180_Y464_C1.0640.89
461_T484_A1.0620.89
445_D638_S1.0620.89
474_E521_D1.0610.89
104_S154_V1.0590.89
134_L189_M1.0540.88
486_R615_E1.0520.88
447_G451_I1.0520.88
485_A619_Q1.0520.88
650_V723_T1.0510.88
457_A568_I1.0500.88
573_F702_V1.0490.88
469_L480_A1.0460.88
482_A615_E1.0460.88
703_T706_G1.0450.88
105_A228_F1.0440.88
586_T589_E1.0420.88
77_G94_V1.0380.88
133_V165_I1.0370.88
295_E354_D1.0370.88
177_D467_R1.0340.87
656_L704_A1.0310.87
212_M347_S1.0300.87
580_V699_I1.0290.87
444_S448_V1.0280.87
269_V330_R1.0270.87
465_N483_E1.0210.87
261_E337_I1.0180.87
92_A194_I1.0150.86
301_I313_M1.0140.86
305_E308_M1.0130.86
29_A32_E1.0110.86
706_G723_T1.0100.86
337_I340_K1.0100.86
73_R496_L1.0090.86
46_I369_L1.0080.86
139_F151_F1.0060.86
625_A630_F1.0040.86
637_V642_L1.0030.86
661_T711_Q1.0010.86
64_L67_F0.9990.86
571_Q652_T0.9990.86
383_K508_E0.9960.85
94_V128_A0.9930.85
418_P421_A0.9930.85
63_I513_F0.9930.85
141_E181_E0.9900.85
448_V451_I0.9860.85
314_M359_L0.9840.85
286_M325_V0.9830.85
445_D451_I0.9830.85
146_R150_L0.9830.85
494_E623_L0.9760.84
206_G327_E0.9740.84
283_S357_L0.9720.84
433_M441_A0.9650.83
494_E563_E0.9590.83
299_D363_G0.9580.83
583_I621_A0.9560.83
650_V654_E0.9560.83
372_D376_E0.9540.83
29_A33_S0.9540.83
444_S491_S0.9540.83
690_E698_H0.9530.83
461_T488_I0.9520.83
474_E519_A0.9520.83
151_F426_V0.9510.83
451_I456_K0.9490.82
228_F243_A0.9470.82
105_A184_P0.9460.82
638_S648_E0.9460.82
414_L644_V0.9440.82
267_A333_E0.9420.82
689_F693_V0.9410.82
171_G461_T0.9380.82
688_A692_T0.9380.82
326_I334_I0.9330.81
206_G269_V0.9320.81
413_A599_T0.9300.81
159_A188_A0.9270.81
514_W518_K0.9250.81
611_D614_V0.9250.81
575_Q632_Q0.9230.81
651_M727_E0.9230.81
156_A160_G0.9220.81
120_I167_I0.9210.81
725_E729_V0.9200.80
396_E605_G0.9200.80
573_F656_L0.9190.80
415_L420_I0.9180.80
298_L361_H0.9170.80
408_N719_I0.9140.80
492_G563_E0.9120.80
21_M44_I0.9070.80
42_T367_C0.9040.79
30_L33_S0.9020.79
303_Q308_M0.9000.79
70_S74_V0.9000.79
360_T363_G0.8970.79
74_V77_G0.8960.79
662_V668_L0.8960.79
724_K727_E0.8950.79
206_G209_N0.8940.79
142_L151_F0.8930.78
613_D624_D0.8930.78
62_P69_T0.8930.78
147_V151_F0.8930.78
628_K692_T0.8920.78
212_M345_A0.8890.78
580_V660_V0.8870.78
212_M331_E0.8860.78
336_D340_K0.8840.78
80_E93_V0.8840.78
689_F696_A0.8830.78
625_A679_V0.8830.78
411_L719_I0.8830.78
729_V732_G0.8820.78
92_A199_I0.8790.77
487_N648_E0.8790.77
220_R305_E0.8760.77
421_A734_I0.8740.77
622_L626_I0.8720.77
120_I133_V0.8710.77
324_L334_I0.8710.77
83_G128_A0.8690.77
232_E509_K0.8690.77
489_I626_I0.8690.77
412_K416_Q0.8670.76
369_L375_A0.8670.76
415_L726_L0.8670.76
578_D683_K0.8640.76
681_V685_H0.8600.76
500_D556_I0.8570.76
191_V559_V0.8560.75
28_F32_E0.8540.75
497_A532_T0.8530.75
397_T602_R0.8520.75
11_Q14_E0.8510.75
678_V699_I0.8500.75
624_D692_T0.8500.75
725_E728_R0.8490.75
373_A377_E0.8490.75
621_A625_A0.8470.75
19_Q25_D0.8450.74
235_D546_N0.8450.74
687_A690_E0.8430.74
70_S528_N0.8430.74
466_A555_V0.8420.74
62_P70_S0.8410.74
81_G125_S0.8400.74
614_V617_S0.8390.74
437_N452_R0.8370.74
630_F692_T0.8360.74
109_Y247_G0.8360.74
128_A191_V0.8360.74
698_H701_E0.8350.74
204_A209_N0.8340.74
140_G181_E0.8330.73
690_E694_K0.8300.73
623_L627_K0.8290.73
66_K70_S0.8280.73
134_L171_G0.8230.73
228_F513_F0.8220.72
498_V558_M0.8210.72
207_V292_S0.8210.72
483_E648_E0.8200.72
395_L398_D0.8200.72
651_M654_E0.8190.72
339_D345_A0.8190.72
144_S147_V0.8180.72
469_L476_G0.8180.72
234_S237_S0.8170.72
328_R350_H0.8170.72
311_Y315_L0.8150.72
644_V647_A0.8140.72
650_V680_S0.8140.72
446_A568_I0.8130.72
483_E487_N0.8130.72
23_V31_I0.8130.72
131_I458_L0.8110.71
89_D195_N0.8110.71
91_Q193_L0.8100.71
187_N503_N0.8100.71
527_C534_V0.8080.71
525_E528_N0.8080.71
569_T631_V0.8070.71
488_I558_M0.8060.71
683_K686_Q0.8050.71
288_S372_D0.8030.71
485_A496_L0.8020.71
407_A411_L0.8010.70
333_E337_I0.7990.70
720_H725_E0.7980.70
384_P510_P0.7980.70
93_V561_L0.7980.70
487_N635_H0.7970.70
68_P533_P0.7960.70
169_T447_G0.7920.70
300_L362_K0.7920.70
579_L684_E0.7910.70
620_K624_D0.7910.70
59_N513_F0.7890.69
688_A711_Q0.7890.69
407_A670_F0.7850.69
232_E544_E0.7850.69
147_V181_E0.7840.69
73_R85_V0.7830.69
526_A610_I0.7790.68
487_N638_S0.7790.68
499_T555_V0.7780.68
136_S173_E0.7760.68
635_H638_S0.7760.68
574_K577_G0.7750.68
86_D90_N0.7750.68
281_S536_G0.7740.68
575_Q702_V0.7730.68
516_I520_A0.7720.68
59_N383_K0.7710.68
658_A700_G0.7700.67
483_E635_H0.7680.67
455_K565_T0.7640.67
270_G541_L0.7640.67
569_T634_A0.7630.67
75_L199_I0.7630.67
63_I67_F0.7620.67
165_I190_C0.7620.67
141_E597_K0.7590.66
444_S571_Q0.7590.66
707_I722_Q0.7580.66
414_L643_G0.7580.66
526_A612_L0.7570.66
475_V609_Q0.7570.66
589_E609_Q0.7550.66
422_S734_I0.7550.66
485_A558_M0.7540.66
617_S699_I0.7530.66
482_A486_R0.7530.66
440_V568_I0.7530.66
574_K578_D0.7530.66
691_A694_K0.7520.66
198_D264_Q0.7510.66
82_A85_V0.7510.66
632_Q685_H0.7510.66
636_D639_E0.7500.65
656_L703_T0.7500.65
587_K673_S0.7470.65
179_S470_Y0.7470.65
432_Y442_P0.7460.65
109_Y159_A0.7460.65
464_C469_L0.7450.65
577_G701_E0.7450.65
356_M370_P0.7450.65
681_V684_E0.7440.65
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432_Y441_A0.7380.64
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484_A500_D0.7260.63
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424_E734_I0.7240.63
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106_L228_F0.7210.62
724_K728_R0.7210.62
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624_D695_D0.7200.62
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687_A691_A0.7010.60
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703_T709_A0.6830.58
706_G722_Q0.6830.58
301_I348_V0.6820.58
150_L184_P0.6820.58
276_A279_L0.6810.58
459_A562_I0.6800.58
574_K656_L0.6800.58
463_D487_N0.6790.58
298_L359_L0.6780.58
573_F650_V0.6770.58
686_Q689_F0.6770.58
683_K687_A0.6770.58
625_A629_G0.6760.57
719_I726_L0.6760.57
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147_V150_L0.6720.57
410_M414_L0.6720.57
706_G724_K0.6710.57
218_T303_Q0.6700.57
202_G289_K0.6700.57
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194_I199_I0.6690.57
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284_A357_L0.6680.56
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575_Q709_A0.6260.52
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109_Y156_A0.6200.51
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635_H639_E0.6190.51
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231_E240_K0.6190.51
651_M723_T0.6190.51
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303_Q306_T0.6170.51
124_F256_L0.6160.51
240_K243_A0.6160.51
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336_D659_N0.6150.50
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302_P345_A0.6140.50
655_N724_K0.6140.50
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252_E318_S0.6130.50
481_V556_I0.6120.50
491_S569_T0.6120.50
209_N277_A0.6110.50
49_V224_H0.6110.50
185_L553_T0.6100.50
440_V448_V0.6100.50
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662_V669_L0.5690.45
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339_D705_D0.5690.45
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705_D709_A0.5650.45
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21_M41_Y0.5630.45
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446_A490_C0.5620.44
300_L346_V0.5620.44
74_V85_V0.5620.44
200_K271_I0.5600.44
42_T311_Y0.5600.44
634_A679_V0.5590.44
478_K529_V0.5580.44
701_E711_Q0.5580.44
586_T671_S0.5580.44
650_V656_L0.5580.44
705_D722_Q0.5570.44
457_A562_I0.5570.44
681_V692_T0.5560.44
223_I240_K0.5560.44
220_R311_Y0.5560.44
62_P67_F0.5560.44
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399_V666_A0.5530.43
67_F70_S0.5520.43
293_G353_D0.5520.43
590_F671_S0.5520.43
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261_E341_Y0.5510.43
146_R151_F0.5510.43
520_A556_I0.5510.43
632_Q649_S0.5510.43
12_I15_E0.5500.43
148_K152_E0.5490.43
62_P517_E0.5480.43
658_A726_L0.5480.43
46_I374_L0.5470.43
699_I724_K0.5460.43
579_L702_V0.5450.43
621_A696_A0.5450.43
486_R650_V0.5450.43
659_N720_H0.5450.43
690_E699_I0.5440.42
388_P514_W0.5430.42
498_V532_T0.5430.42
308_M508_E0.5430.42
64_L78_P0.5430.42
335_I346_V0.5420.42
211_V274_M0.5420.42
41_Y309_T0.5410.42
595_L666_A0.5410.42
583_I696_A0.5390.42
632_Q702_V0.5390.42
46_I376_E0.5390.42
62_P74_V0.5380.42
477_G554_P0.5370.42
126_M202_G0.5370.42
226_A279_L0.5370.42
406_D410_M0.5360.42
132_A460_M0.5350.41
478_K610_I0.5350.41
631_V691_A0.5350.41
621_A695_D0.5350.41
94_V194_I0.5350.41
213_Y282_S0.5350.41
493_A560_G0.5340.41
270_G294_I0.5340.41
617_S620_K0.5330.41
71_G270_G0.5330.41
78_P81_G0.5330.41
396_E399_V0.5320.41
369_L374_L0.5320.41
485_A530_L0.5310.41
637_V669_L0.5310.41
12_I16_K0.5310.41
146_R152_E0.5310.41
731_K735_P0.5310.41
528_N582_V0.5300.41
60_S99_S0.5300.41
297_N310_A0.5300.41
167_I256_L0.5290.41
439_V457_A0.5280.41
465_N468_Y0.5280.41
619_Q675_S0.5280.41
32_E38_L0.5280.41
251_M254_L0.5270.41
492_G567_H0.5270.41
577_G704_A0.5270.41
433_M442_P0.5270.41
257_E430_Y0.5260.40
70_S76_Q0.5260.40
59_N384_P0.5260.40
617_S631_V0.5260.40
224_H523_I0.5260.40
209_N283_S0.5250.40
91_Q563_E0.5250.40
99_S539_V0.5250.40
93_V451_I0.5250.40
468_Y591_A0.5230.40
61_K65_R0.5230.40
173_E462_T0.5230.40
318_S348_V0.5220.40
57_Y539_V0.5210.40
491_S626_I0.5210.40
555_V701_E0.5200.40
59_N63_I0.5200.40
658_A710_I0.5200.40
164_C430_Y0.5200.40
74_V533_P0.5190.40
178_S688_A0.5190.40
619_Q626_I0.5180.40
647_A660_V0.5180.40
214_V324_L0.5180.40
468_Y608_P0.5180.40
575_Q720_H0.5170.39
59_N105_A0.5170.39
76_Q281_S0.5160.39
58_K96_K0.5160.39
501_N555_V0.5160.39
296_M359_L0.5160.39
728_R731_K0.5150.39
462_T555_V0.5150.39
104_S186_V0.5150.39
249_P477_G0.5140.39
276_A541_L0.5140.39
287_A355_K0.5140.39
140_G177_D0.5140.39
266_D333_E0.5130.39
102_H113_A0.5130.39
129_R435_R0.5130.39
220_R315_L0.5130.39
84_I194_I0.5130.39
46_I314_M0.5130.39
686_Q692_T0.5120.39
614_V682_K0.5120.39
420_I594_E0.5120.39
601_G664_G0.5120.39
279_L301_I0.5110.39
106_L513_F0.5110.39
75_L78_P0.5110.39
295_E365_V0.5110.39
580_V637_V0.5110.39
576_A579_L0.5110.39
387_E391_Y0.5100.39
723_T726_L0.5100.39
72_E533_P0.5100.39
183_N542_Y0.5090.39
701_E705_D0.5090.39
510_P645_A0.5090.39
397_T596_Q0.5090.39
664_G691_A0.5090.39
407_A669_L0.5090.39
75_L79_G0.5070.38
501_N523_I0.5070.38
204_A269_V0.5060.38
621_A631_V0.5060.38
390_Y515_Q0.5060.38
659_N725_E0.5060.38
589_E674_Q0.5050.38
382_H385_S0.5050.38
663_E668_L0.5050.38
116_V161_Y0.5040.38
63_I517_E0.5040.38
706_G728_R0.5040.38
133_V158_I0.5040.38
492_G626_I0.5040.38
579_L682_K0.5040.38
567_H682_K0.5040.38
105_A134_L0.5040.38
283_S287_A0.5030.38
614_V675_S0.5030.38
419_T597_K0.5030.38
161_Y252_E0.5030.38
159_A164_C0.5020.38
27_E224_H0.5020.38
280_T357_L0.5020.38
303_Q434_V0.5010.38
84_I94_V0.5010.38
77_G80_E0.5000.38
686_Q696_A0.5000.38
71_G203_Q0.5000.38
685_H701_E0.5000.38
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4lgyA 1 0.965 100 0.34 Contact Map
3viuA 1 0.9394 100 0.347 Contact Map
1vk3A 1 0.779 100 0.465 Contact Map
2zodA 2 0.3895 100 0.847 Contact Map
3u0oA 2 0.3989 100 0.854 Contact Map
3vtiC 2 0.3774 100 0.861 Contact Map
2rb9A 2 0.4057 100 0.863 Contact Map
3fd5A 2 0.434 100 0.863 Contact Map
3wjpA 2 0.4218 100 0.869 Contact Map
2z01A 2 0.3774 100 0.87 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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