6PGDH - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

6PGDH - 6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating

UniProt:	P12013	Sequences: MFNSIGVIGLGVMGSNIALNMANKGENVAVYNYTRDLTDQLIQKLDGQSLSPYYELEDFVQSLEKPRKIFLMVTAGKPVDSVIQSLKPLLEEGDVIMDGGNSHYEDTERRYDELKEKGIGYLGVGISGGEVGALTGPSIMPGGDRDVYEKAAPILTKIAAQVGDDPCCVYIGPKGAGHFTKMVHNGIEYADMQLIAEAYTFLRETLRLPLDEIASIFETWNQGELKSYLIEITAEILRKKDEKTGQPLIDVILDKTGQKGTGKWTSMQAIDNGIPSTIITESLFARYLSSLKEERMAAQDVLAGPEAEEKHLDKDTWIEYVRQALYMGKVCAYAQGFAQYKMSSELYGWNLPLKDIALIFRGGCIIRADFLNVISEAFSEQPNLANLLIAPYFTDKLHAYQTGLRKVVCEGISTGISFPCLTTALSYYDGYRTGRSNANLLQAQRDYFGAHTYERTDMDGVFHTNWSE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	468 (463)
Sequences:	1774 (909)
Seq/√Len:	42.2

ECOLI - 6PGD
BACSU - 6PGDH 6PGD

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
320_Y	406_K	4.611	1.00
453_Y	464_T	4.146	1.00
84_Q	113_E	3.636	1.00
108_E	174_K	3.488	1.00
4_S	64_E	3.370	1.00
23_N	134_L	3.365	1.00
224_E	322_R	3.326	1.00
210_L	247_P	3.182	1.00
56_L	89_L	3.095	1.00
380_E	390_A	2.982	1.00
212_E	314_K	2.962	1.00
351_L	356_I	2.896	1.00
202_L	321_V	2.890	1.00
29_A	62_S	2.851	1.00
319_E	322_R	2.849	1.00
209_P	212_E	2.804	1.00
214_A	238_R	2.758	1.00
200_T	204_E	2.729	1.00
411_G	418_F	2.725	1.00
215_S	238_R	2.676	1.00
340_Y	351_L	2.673	1.00
42_I	52_P	2.633	1.00
302_L	428_Y	2.613	1.00
352_P	355_D	2.483	1.00
152_A	156_T	2.457	1.00
218_E	238_R	2.457	1.00
3_N	29_A	2.446	1.00
208_L	216_I	2.427	1.00
235_E	447_Y	2.414	1.00
213_I	237_L	2.412	1.00
60_V	89_L	2.409	1.00
124_V	139_I	2.377	1.00
6_G	59_F	2.361	1.00
202_L	208_L	2.353	1.00
248_L	252_I	2.332	1.00
162_V	362_G	2.331	1.00
122_L	151_A	2.328	1.00
95_V	150_K	2.320	1.00
65_K	91_E	2.260	1.00
288_L	430_G	2.255	1.00
244_T	251_V	2.212	1.00
39_D	54_Y	2.208	1.00
294_E	431_Y	2.204	1.00
408_V	412_I	2.189	1.00
55_E	58_D	2.188	1.00
77_K	81_S	2.175	1.00
173_P	344_S	2.165	1.00
26_E	157_K	2.131	0.99
323_Q	403_G	2.115	0.99
409_C	413_S	2.075	0.99
211_D	240_K	2.075	0.99
39_D	43_Q	2.068	0.99
104_Y	347_Y	2.060	0.99
210_L	250_D	2.032	0.99
57_E	61_Q	2.028	0.99
83_I	96_I	2.010	0.99
196_A	441_L	1.979	0.99
11_G	74_T	1.979	0.99
327_M	404_L	1.979	0.99
236_I	443_A	1.968	0.99
292_K	296_M	1.967	0.99
408_V	422_T	1.930	0.99
68_K	150_K	1.894	0.99
208_L	318_I	1.872	0.99
22_A	48_Q	1.856	0.98
190_A	332_A	1.841	0.98
169_V	355_D	1.830	0.98
203_R	210_L	1.821	0.98
375_S	379_S	1.797	0.98
219_T	222_Q	1.776	0.98
373_V	376_E	1.771	0.98
313_D	316_T	1.764	0.98
395_D	399_A	1.762	0.98
297_A	385_A	1.740	0.98
18_A	30_V	1.739	0.98
201_F	317_W	1.734	0.98
202_L	213_I	1.731	0.98
87_K	117_K	1.713	0.97
328_G	421_L	1.707	0.97
145_R	149_E	1.693	0.97
319_E	323_Q	1.691	0.97
191_D	329_K	1.686	0.97
10_L	41_L	1.685	0.97
79_V	102_S	1.678	0.97
246_Q	251_V	1.674	0.97
83_I	114_L	1.671	0.97
410_E	413_S	1.659	0.97
201_F	321_V	1.645	0.97
422_T	426_S	1.639	0.97
5_I	21_M	1.631	0.97
87_K	119_I	1.614	0.96
454_E	461_V	1.605	0.96
165_D	358_L	1.601	0.96
406_K	413_S	1.595	0.96
405_R	429_D	1.580	0.96
231_E	367_R	1.578	0.96
388_L	397_L	1.550	0.95
216_I	318_I	1.545	0.95
304_G	401_Q	1.542	0.95
30_V	41_L	1.529	0.95
198_A	321_V	1.529	0.95
113_E	116_E	1.528	0.95
323_Q	399_A	1.528	0.95
320_Y	403_G	1.509	0.95
179_F	268_Q	1.500	0.94
8_I	31_Y	1.494	0.94
69_I	96_I	1.489	0.94
202_L	206_L	1.486	0.94
269_A	284_F	1.482	0.94
149_E	152_A	1.481	0.94
131_V	135_T	1.478	0.94
384_L	390_A	1.468	0.94
305_P	401_Q	1.454	0.93
205_T	414_T	1.447	0.93
15_S	44_K	1.435	0.93
21_M	70_F	1.423	0.93
53_Y	58_D	1.419	0.93
224_E	319_E	1.411	0.92
21_M	154_I	1.408	0.92
219_T	322_R	1.407	0.92
23_N	135_T	1.403	0.92
300_D	434_G	1.401	0.92
35_R	39_D	1.400	0.92
299_Q	434_G	1.399	0.92
24_K	157_K	1.397	0.92
328_G	404_L	1.383	0.92
29_A	53_Y	1.382	0.92
380_E	391_P	1.374	0.91
454_E	459_D	1.367	0.91
338_A	427_Y	1.365	0.91
97_M	151_A	1.363	0.91
111_Y	115_K	1.361	0.91
87_K	113_E	1.355	0.91
263_K	271_D	1.354	0.91
115_K	144_D	1.345	0.90
354_K	375_S	1.344	0.90
112_D	116_E	1.339	0.90
304_G	432_R	1.334	0.90
206_L	321_V	1.331	0.90
21_M	28_V	1.331	0.90
219_T	315_D	1.328	0.90
82_V	85_S	1.323	0.90
435_R	456_T	1.323	0.90
409_C	412_I	1.318	0.89
214_A	237_L	1.318	0.89
277_T	331_C	1.310	0.89
248_L	251_V	1.305	0.89
69_I	90_L	1.304	0.89
169_V	359_I	1.296	0.89
123_G	142_G	1.296	0.89
10_L	30_V	1.295	0.89
45_L	50_L	1.273	0.88
344_S	353_L	1.268	0.88
53_Y	59_F	1.260	0.87
223_G	322_R	1.256	0.87
102_S	106_D	1.252	0.87
53_Y	62_S	1.241	0.86
213_I	321_V	1.232	0.86
343_S	347_Y	1.225	0.86
218_E	222_Q	1.221	0.85
454_E	460_G	1.220	0.85
198_A	421_L	1.219	0.85
255_K	454_E	1.213	0.85
321_V	421_L	1.211	0.85
280_T	284_F	1.211	0.85
327_M	400_Y	1.209	0.85
354_K	379_S	1.207	0.85
240_K	247_P	1.198	0.84
11_G	32_N	1.195	0.84
109_R	113_E	1.188	0.84
7_V	70_F	1.182	0.84
72_M	158_I	1.179	0.83
344_S	350_N	1.177	0.83
3_N	51_S	1.146	0.82
183_V	339_Q	1.143	0.81
455_R	462_F	1.143	0.81
171_I	359_I	1.141	0.81
317_W	410_E	1.141	0.81
205_T	416_I	1.138	0.81
33_Y	74_T	1.134	0.81
36_D	40_Q	1.130	0.81
38_T	54_Y	1.126	0.80
183_V	265_T	1.125	0.80
35_R	54_Y	1.124	0.80
202_L	216_I	1.123	0.80
103_H	267_M	1.119	0.80
32_N	38_T	1.117	0.80
22_A	134_L	1.117	0.80
415_G	432_R	1.113	0.80
74_T	78_P	1.108	0.79
458_M	462_F	1.107	0.79
236_I	444_Q	1.106	0.79
157_K	161_Q	1.102	0.79
341_K	345_E	1.096	0.79
19_L	134_L	1.086	0.78
72_M	139_I	1.083	0.78
342_M	345_E	1.080	0.78
201_F	411_G	1.078	0.77
297_A	300_D	1.076	0.77
302_L	305_P	1.075	0.77
203_R	250_D	1.068	0.77
302_L	432_R	1.067	0.77
417_S	433_T	1.067	0.77
171_I	356_I	1.065	0.77
358_L	375_S	1.065	0.77
418_F	422_T	1.063	0.76
226_K	369_D	1.060	0.76
15_S	134_L	1.059	0.76
394_T	398_H	1.058	0.76
5_I	97_M	1.057	0.76
38_T	52_P	1.049	0.75
437_N	440_L	1.047	0.75
242_E	464_T	1.047	0.75
22_A	49_S	1.042	0.75
120_G	144_D	1.040	0.75
173_P	350_N	1.033	0.74
70_F	97_M	1.031	0.74
272_N	347_Y	1.031	0.74
138_S	360_F	1.028	0.74
11_G	33_Y	1.021	0.73
17_I	158_I	1.019	0.73
219_T	223_G	1.016	0.73
107_T	123_G	1.014	0.73
412_I	418_F	1.009	0.73
29_A	59_F	1.009	0.73
69_I	88_P	1.008	0.73
78_P	81_S	0.997	0.72
108_E	347_Y	0.993	0.71
139_I	159_A	0.993	0.71
258_Q	263_K	0.991	0.71
247_P	250_D	0.989	0.71
266_S	280_T	0.986	0.71
7_V	28_V	0.985	0.71
401_Q	432_R	0.984	0.71
59_F	62_S	0.975	0.70
304_G	428_Y	0.968	0.69
34_T	37_L	0.964	0.69
298_A	431_Y	0.962	0.69
294_E	386_N	0.961	0.69
171_I	176_A	0.959	0.69
326_Y	396_K	0.955	0.68
272_N	346_L	0.954	0.68
249_I	440_L	0.951	0.68
239_K	464_T	0.950	0.68
7_V	30_V	0.948	0.68
148_Y	152_A	0.946	0.68
253_L	292_K	0.939	0.67
278_I	331_C	0.938	0.67
270_I	283_L	0.932	0.66
195_I	325_L	0.931	0.66
214_A	218_E	0.931	0.66
190_A	278_I	0.930	0.66
200_T	437_N	0.930	0.66
108_E	112_D	0.929	0.66
99_G	139_I	0.929	0.66
148_Y	169_V	0.928	0.66
334_A	386_N	0.925	0.66
204_E	433_T	0.925	0.66
71_L	96_I	0.925	0.66
253_L	455_R	0.922	0.66
122_L	170_Y	0.921	0.66
27_N	51_S	0.914	0.65
148_Y	170_Y	0.912	0.65
195_I	230_I	0.912	0.65
401_Q	428_Y	0.910	0.65
163_G	362_G	0.910	0.65
426_S	429_D	0.909	0.64
15_S	22_A	0.906	0.64
162_V	165_D	0.904	0.64
124_V	155_L	0.903	0.64
111_Y	144_D	0.895	0.63
433_T	436_S	0.895	0.63
323_Q	400_Y	0.892	0.63
145_R	170_Y	0.889	0.63
372_N	376_E	0.888	0.63
282_S	420_C	0.887	0.63
239_K	248_L	0.885	0.62
412_I	426_S	0.884	0.62
303_A	398_H	0.884	0.62
37_L	40_Q	0.882	0.62
27_N	49_S	0.879	0.62
107_T	121_Y	0.879	0.62
165_D	361_R	0.878	0.62
74_T	77_K	0.875	0.61
202_L	318_I	0.875	0.61
120_G	146_D	0.868	0.61
105_E	271_D	0.867	0.61
294_E	338_A	0.865	0.61
233_T	444_Q	0.865	0.61
281_E	284_F	0.862	0.60
457_D	462_F	0.856	0.60
429_D	432_R	0.856	0.60
381_Q	390_A	0.853	0.60
417_S	436_S	0.852	0.59
145_R	350_N	0.845	0.59
5_I	70_F	0.844	0.59
153_P	159_A	0.843	0.59
194_L	420_C	0.842	0.59
200_T	203_R	0.840	0.58
370_F	392_Y	0.840	0.58
221_N	231_E	0.839	0.58
99_G	126_I	0.838	0.58
35_R	38_T	0.838	0.58
112_D	115_K	0.837	0.58
278_I	424_A	0.835	0.58
258_Q	287_Y	0.835	0.58
142_G	176_A	0.834	0.58
298_A	389_I	0.829	0.57
342_M	346_L	0.828	0.57
258_Q	267_M	0.826	0.57
316_T	320_Y	0.826	0.57
43_Q	46_D	0.826	0.57
281_E	420_C	0.819	0.56
201_F	418_F	0.818	0.56
210_L	249_I	0.817	0.56
118_G	151_A	0.815	0.56
412_I	425_L	0.815	0.56
124_V	151_A	0.815	0.56
95_V	122_L	0.812	0.56
126_I	139_I	0.810	0.56
206_L	317_W	0.809	0.55
326_Y	392_Y	0.804	0.55
315_D	319_E	0.804	0.55
370_F	393_F	0.804	0.55
398_H	428_Y	0.802	0.55
114_L	119_I	0.800	0.55
138_S	359_I	0.800	0.55
24_K	161_Q	0.800	0.55
274_I	342_M	0.799	0.55
103_H	268_Q	0.798	0.54
6_G	9_G	0.798	0.54
280_T	349_W	0.797	0.54
212_E	215_S	0.797	0.54
7_V	10_L	0.797	0.54
60_V	90_L	0.794	0.54
4_S	27_N	0.794	0.54
340_Y	356_I	0.789	0.54
3_N	27_N	0.789	0.54
326_Y	370_F	0.788	0.54
402_T	406_K	0.787	0.53
23_N	44_K	0.786	0.53
175_G	349_W	0.786	0.53
73_V	79_V	0.780	0.53
54_Y	58_D	0.780	0.53
438_A	441_L	0.779	0.53
64_E	68_K	0.777	0.52
19_L	45_L	0.775	0.52
70_F	99_G	0.775	0.52
302_L	398_H	0.773	0.52
269_A	276_S	0.771	0.52
18_A	21_M	0.768	0.52
18_A	29_A	0.766	0.51
205_T	410_E	0.764	0.51
78_P	82_V	0.764	0.51
7_V	72_M	0.763	0.51
32_N	74_T	0.761	0.51
355_D	358_L	0.759	0.51
297_A	389_I	0.755	0.50
81_S	85_S	0.755	0.50
139_I	346_L	0.755	0.50
139_I	168_C	0.753	0.50
242_E	245_G	0.753	0.50
405_R	415_G	0.751	0.50
147_V	151_A	0.751	0.50
40_Q	43_Q	0.748	0.50
115_K	146_D	0.748	0.50
296_M	434_G	0.747	0.50
340_Y	360_F	0.747	0.50
168_C	258_Q	0.741	0.49
244_T	247_P	0.739	0.49
18_A	50_L	0.739	0.49
222_Q	246_Q	0.736	0.49
248_L	456_T	0.734	0.48
19_L	23_N	0.733	0.48
149_E	170_Y	0.732	0.48
22_A	50_L	0.730	0.48
139_I	151_A	0.730	0.48
70_F	155_L	0.729	0.48
357_A	374_I	0.728	0.48
208_L	314_K	0.728	0.48
174_K	347_Y	0.726	0.48
415_G	429_D	0.724	0.47
149_E	153_P	0.722	0.47
216_I	237_L	0.721	0.47
73_V	78_P	0.717	0.47
272_N	342_M	0.716	0.47
174_K	348_G	0.716	0.47
368_A	427_Y	0.710	0.46
33_Y	37_L	0.710	0.46
268_Q	271_D	0.707	0.46
120_G	150_K	0.706	0.46
210_L	246_Q	0.705	0.46
337_F	441_L	0.703	0.46
15_S	41_L	0.703	0.46
281_E	423_T	0.702	0.45
291_L	294_E	0.702	0.45
272_N	343_S	0.699	0.45
71_L	82_V	0.698	0.45
69_I	89_L	0.697	0.45
72_M	228_Y	0.696	0.45
3_N	62_S	0.696	0.45
298_A	432_R	0.695	0.45
337_F	349_W	0.695	0.45
331_C	404_L	0.693	0.45
302_L	401_Q	0.692	0.44
255_K	441_L	0.690	0.44
219_T	224_E	0.690	0.44
310_K	313_D	0.688	0.44
92_E	146_D	0.686	0.44
437_N	441_L	0.686	0.44
69_I	91_E	0.684	0.44
301_V	394_T	0.683	0.44
374_I	377_A	0.682	0.44
215_S	219_T	0.682	0.44
293_E	296_M	0.682	0.44
108_E	349_W	0.681	0.43
79_V	339_Q	0.681	0.43
322_R	400_Y	0.680	0.43
314_K	318_I	0.680	0.43
175_G	191_D	0.679	0.43
337_F	353_L	0.679	0.43
376_E	392_Y	0.676	0.43
233_T	440_L	0.674	0.43
284_F	349_W	0.672	0.43
32_N	72_M	0.672	0.43
37_L	73_V	0.672	0.43
192_M	444_Q	0.672	0.43
241_D	244_T	0.671	0.43
81_S	84_Q	0.670	0.42
194_L	325_L	0.670	0.42
428_Y	432_R	0.668	0.42
203_R	378_F	0.668	0.42
405_R	426_S	0.667	0.42
354_K	370_F	0.667	0.42
331_C	368_A	0.665	0.42
114_L	424_A	0.662	0.42
141_P	169_V	0.661	0.42
327_M	397_L	0.660	0.42
44_K	134_L	0.660	0.42
224_E	400_Y	0.658	0.41
329_K	370_F	0.656	0.41
120_G	151_A	0.656	0.41
124_V	168_C	0.655	0.41
199_Y	203_R	0.655	0.41
55_E	59_F	0.654	0.41
208_L	212_E	0.654	0.41
32_N	37_L	0.653	0.41
224_E	323_Q	0.652	0.41
141_P	171_I	0.652	0.41
41_L	50_L	0.651	0.41
30_V	34_T	0.650	0.41
139_I	164_D	0.649	0.41
444_Q	447_Y	0.649	0.41
218_E	234_A	0.649	0.41
119_I	144_D	0.649	0.41
191_D	195_I	0.646	0.40
316_T	406_K	0.646	0.40
61_Q	64_E	0.645	0.40
385_A	395_D	0.644	0.40
343_S	441_L	0.643	0.40
50_L	134_L	0.643	0.40
265_T	276_S	0.642	0.40
45_L	48_Q	0.641	0.40
391_P	394_T	0.641	0.40
373_V	396_K	0.640	0.40
34_T	41_L	0.639	0.40
231_E	234_A	0.638	0.40
74_T	126_I	0.638	0.40
268_Q	339_Q	0.637	0.39
20_N	189_Y	0.637	0.39
200_T	433_T	0.635	0.39
377_A	390_A	0.634	0.39
253_L	457_D	0.634	0.39
57_E	89_L	0.632	0.39
228_Y	447_Y	0.632	0.39
108_E	111_Y	0.631	0.39
228_Y	232_I	0.631	0.39
7_V	18_A	0.630	0.39
320_Y	323_Q	0.629	0.39
373_V	392_Y	0.628	0.39
99_G	155_L	0.627	0.39
322_R	403_G	0.625	0.38
287_Y	290_S	0.625	0.38
111_Y	174_K	0.624	0.38
153_P	157_K	0.623	0.38
337_F	392_Y	0.622	0.38
24_K	135_T	0.621	0.38
241_D	455_R	0.620	0.38
72_M	134_L	0.619	0.38
195_I	329_K	0.619	0.38
30_V	53_Y	0.619	0.38
169_V	176_A	0.619	0.38
331_C	334_A	0.618	0.38
132_G	189_Y	0.618	0.38
206_L	318_I	0.617	0.38
126_I	444_Q	0.617	0.38
22_A	47_G	0.615	0.37
114_L	121_Y	0.614	0.37
73_V	82_V	0.614	0.37
317_W	407_V	0.613	0.37
84_Q	87_K	0.613	0.37
155_L	168_C	0.612	0.37
191_D	349_W	0.612	0.37
329_K	349_W	0.609	0.37
90_L	96_I	0.609	0.37
281_E	430_G	0.609	0.37
274_I	338_A	0.608	0.37
301_V	391_P	0.608	0.37
200_T	205_T	0.606	0.37
194_L	278_I	0.606	0.37
134_L	268_Q	0.605	0.37
102_S	121_Y	0.605	0.37
8_I	56_L	0.605	0.37
211_D	222_Q	0.605	0.37
230_I	233_T	0.604	0.37
26_E	154_I	0.603	0.36
132_G	140_M	0.603	0.36
15_S	23_N	0.602	0.36
107_T	174_K	0.601	0.36
294_E	322_R	0.601	0.36
141_P	168_C	0.601	0.36
36_D	39_D	0.601	0.36
241_D	247_P	0.600	0.36
254_D	295_R	0.600	0.36
24_K	84_Q	0.600	0.36
375_S	397_L	0.600	0.36
410_E	414_T	0.598	0.36
159_A	168_C	0.598	0.36
114_L	117_K	0.598	0.36
403_G	406_K	0.596	0.36
210_L	237_L	0.596	0.36
397_L	404_L	0.594	0.36
276_S	331_C	0.593	0.36
23_N	48_Q	0.592	0.35
319_E	403_G	0.592	0.35
179_F	343_S	0.592	0.35
41_L	45_L	0.591	0.35
56_L	85_S	0.590	0.35
63_L	69_I	0.589	0.35
113_E	117_K	0.589	0.35
241_D	251_V	0.589	0.35
209_P	314_K	0.588	0.35
305_P	432_R	0.588	0.35
267_M	277_T	0.588	0.35
228_Y	357_A	0.588	0.35
327_M	428_Y	0.587	0.35
281_E	285_A	0.585	0.35
159_A	165_D	0.585	0.35
178_H	258_Q	0.584	0.35
92_E	117_K	0.584	0.35
72_M	285_A	0.583	0.35
198_A	201_F	0.582	0.35
350_N	353_L	0.582	0.35
148_Y	156_T	0.582	0.35
173_P	356_I	0.580	0.34
154_I	157_K	0.580	0.34
162_V	375_S	0.580	0.34
257_G	290_S	0.579	0.34
11_G	78_P	0.578	0.34
396_K	399_A	0.578	0.34
199_Y	437_N	0.577	0.34
57_E	88_P	0.576	0.34
442_Q	445_R	0.576	0.34
58_D	61_Q	0.576	0.34
211_D	247_P	0.576	0.34
38_T	55_E	0.575	0.34
452_T	464_T	0.575	0.34
88_P	92_E	0.574	0.34
138_S	324_A	0.574	0.34
11_G	16_N	0.573	0.34
87_K	114_L	0.572	0.34
234_A	255_K	0.570	0.34
333_Y	393_F	0.567	0.33
418_F	426_S	0.567	0.33
267_M	271_D	0.566	0.33
10_L	32_N	0.566	0.33
31_Y	56_L	0.565	0.33
60_V	86_L	0.565	0.33
377_A	393_F	0.564	0.33
156_T	169_V	0.564	0.33
203_R	213_I	0.563	0.33
344_S	355_D	0.563	0.33
373_V	390_A	0.563	0.33
409_C	417_S	0.562	0.33
115_K	459_D	0.561	0.33
68_K	154_I	0.560	0.33
257_G	444_Q	0.558	0.33
56_L	86_L	0.558	0.33
374_I	393_F	0.558	0.33
278_I	420_C	0.558	0.33
195_I	225_L	0.557	0.33
204_E	416_I	0.555	0.32
337_F	357_A	0.555	0.32
30_V	50_L	0.552	0.32
296_M	299_Q	0.551	0.32
163_G	372_N	0.550	0.32
21_M	97_M	0.550	0.32
30_V	165_D	0.548	0.32
405_R	432_R	0.548	0.32
276_S	339_Q	0.545	0.32
60_V	67_R	0.543	0.31
80_D	110_R	0.543	0.31
16_N	37_L	0.543	0.31
26_E	153_P	0.542	0.31
244_T	248_L	0.542	0.31
430_G	436_S	0.541	0.31
257_G	267_M	0.541	0.31
17_I	70_F	0.541	0.31
277_T	368_A	0.541	0.31
196_A	353_L	0.539	0.31
130_E	450_A	0.539	0.31
395_D	398_H	0.539	0.31
268_Q	274_I	0.538	0.31
36_D	328_G	0.538	0.31
187_I	336_G	0.538	0.31
386_N	431_Y	0.537	0.31
215_S	293_E	0.537	0.31
248_L	465_N	0.536	0.31
191_D	333_Y	0.536	0.31
107_T	114_L	0.536	0.31
20_N	445_R	0.535	0.31
270_I	280_T	0.535	0.31
298_A	405_R	0.534	0.31
270_I	284_F	0.534	0.31
224_E	326_Y	0.534	0.31
276_S	280_T	0.533	0.31
176_A	209_P	0.533	0.31
145_R	173_P	0.533	0.31
152_A	169_V	0.533	0.31
161_Q	362_G	0.532	0.30
104_Y	268_Q	0.532	0.30
207_R	435_R	0.531	0.30
323_Q	327_M	0.531	0.30
200_T	417_S	0.531	0.30
19_L	190_A	0.531	0.30
213_I	230_I	0.531	0.30
115_K	119_I	0.530	0.30
215_S	315_D	0.530	0.30
312_L	414_T	0.529	0.30
30_V	52_P	0.529	0.30
77_K	416_I	0.529	0.30
313_D	317_W	0.528	0.30
11_G	34_T	0.527	0.30
263_K	443_A	0.526	0.30
212_E	313_D	0.525	0.30
115_K	420_C	0.525	0.30
292_K	434_G	0.524	0.30
173_P	348_G	0.524	0.30
202_L	317_W	0.524	0.30
44_K	48_Q	0.523	0.30
92_E	222_Q	0.521	0.30
306_E	315_D	0.521	0.30
71_L	147_V	0.520	0.30
222_Q	383_N	0.520	0.30
16_N	34_T	0.519	0.29
96_I	158_I	0.519	0.29
292_K	431_Y	0.519	0.29
156_T	359_I	0.518	0.29
225_L	374_I	0.518	0.29
218_E	307_A	0.517	0.29
199_Y	439_N	0.517	0.29
59_F	421_L	0.516	0.29
69_I	87_K	0.516	0.29
134_L	427_Y	0.515	0.29
22_A	427_Y	0.515	0.29
93_G	118_G	0.515	0.29
126_I	249_I	0.515	0.29
381_Q	385_A	0.515	0.29
11_G	82_V	0.515	0.29
103_H	272_N	0.513	0.29
23_N	427_Y	0.512	0.29
333_Y	371_L	0.512	0.29
19_L	50_L	0.511	0.29
78_P	102_S	0.511	0.29
43_Q	196_A	0.511	0.29
30_V	59_F	0.510	0.29
78_P	266_S	0.510	0.29
337_F	370_F	0.509	0.29
301_V	389_I	0.507	0.29
71_L	102_S	0.507	0.29
273_G	287_Y	0.506	0.28
189_Y	262_G	0.506	0.28
219_T	319_E	0.506	0.28
285_A	430_G	0.506	0.28
15_S	99_G	0.505	0.28
18_A	70_F	0.504	0.28
189_Y	445_R	0.503	0.28
50_L	111_Y	0.502	0.28
182_M	452_T	0.502	0.28
168_C	359_I	0.502	0.28
11_G	68_K	0.501	0.28
296_M	300_D	0.501	0.28
168_C	430_G	0.500	0.28
448_F	451_H	0.500	0.28

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2p4qA	2	0.9936	100	0.346	Contact Map
2zydA	2	0.9936	100	0.347	Contact Map
1pgjA	2	0.9872	100	0.359	Contact Map
4gwgA	2	0.9915	100	0.363	Contact Map
2iz1A	2	0.9957	100	0.366	Contact Map
4e21A	4	0.6453	100	0.788	Contact Map
3dojA	3	0.6068	100	0.853	Contact Map
3pduA	4	0.6047	100	0.854	Contact Map
3pefA	5	0.6047	100	0.855	Contact Map
3ckyA	4	0.6175	100	0.856	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0131 seconds.