PT1 - BACSU - GREMLIN Contacts

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PT1 - Phosphoenolpyruvate-protein phosphotransferase

UniProt:	P08838	Sequences: MQELKGIGASAGIAIAKAYRLEEPDLTVEKKNISDSEAEVSRFDEAIARSKEELEKIKEHALKELGQDKADIFSAHLLVLSDPELLNPVKEKISTDSVNAEFALKETSSMFVTMFESMDNEYMKERAADIRDVTKRVTGHLLGVEIPNPSMISEEVIIVAEDLTPSDTAQLNREFVKGFTTDIGGRTSHSAIMARSLEIPAVVGTKAATGTIQNGVTVIVDGINGDVIIDPSAETVKEYEEKHNAYLAQKAEWAKLVNEPTVSKDGHHVELAANIGTPDDVKGVLENGGEAVGLYRTEFLYMGRDQLPTEDEQFDAYKTVLERMEGKSVVVRTLDIGGDKELPYLQLPKEMNPFLGYRAIRLCLEEQEIFRTQLRALLRASTYGNLKIMFPMIATVNEFKEAKAILLEEKEKLVKAGQAVSDDIEVGMMVEIPSTAVIADQFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYNPAILRLITLVIEAAHKEGKWVGMCGEMAGDEIAIPILLGLGLDEFSMSATSILPARTQISKLSKQEAESFKEKILSMSTTEEVVAFVKETFK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	570 (518)
Sequences:	6063 (3541)
Seq/√Len:	155.6

ECOLI - PTFX2 PT1 PTFX1 PT1P PPSA
BACSU - PT1
HALSA - Q9HSA1
SULSO - Q97ZL2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
486_T	490_E	5.183	1.00
178_G	220_V	5.128	1.00
400_K	445_E	5.036	1.00
314_F	383_Y	3.779	1.00
493_H	521_D	3.648	1.00
436_A	484_L	3.030	1.00
371_R	408_E	2.916	1.00
324_M	329_V	2.905	1.00
492_A	499_V	2.887	1.00
387_K	425_E	2.832	1.00
357_Y	365_E	2.816	1.00
232_S	235_T	2.814	1.00
318_K	383_Y	2.773	1.00
321_L	386_L	2.756	1.00
44_D	90_K	2.753	1.00
460_T	484_L	2.594	1.00
155_E	177_K	2.594	1.00
501_M	520_L	2.586	1.00
314_F	379_R	2.550	1.00
439_A	491_A	2.493	1.00
371_R	409_E	2.477	1.00
318_K	322_E	2.452	1.00
409_E	412_K	2.429	1.00
377_L	386_L	2.412	1.00
437_V	484_L	2.409	1.00
403_K	445_E	2.378	1.00
371_R	405_I	2.273	1.00
390_F	402_A	2.263	1.00
18_A	218_V	2.250	1.00
541_S	544_E	2.245	1.00
40_V	94_S	2.236	1.00
360_I	393_I	2.206	1.00
444_K	495_E	2.203	1.00
414_V	422_D	2.191	1.00
42_R	101_E	2.183	1.00
282_K	286_E	2.132	1.00
202_V	222_G	2.130	1.00
208_A	212_I	2.114	1.00
43_F	89_V	2.101	1.00
219_I	239_Y	2.095	1.00
333_T	390_F	2.095	1.00
41_S	45_E	2.094	1.00
488_V	499_V	2.090	1.00
414_V	421_S	2.065	1.00
53_E	140_H	2.037	1.00
360_I	402_A	2.035	1.00
374_L	406_L	2.016	1.00
50_S	140_H	2.015	1.00
390_F	406_L	2.012	1.00
512_I	533_A	1.994	1.00
269_V	516_L	1.993	1.00
447_D	494_K	1.985	1.00
328_S	387_K	1.981	1.00
284_V	289_G	1.979	1.00
320_V	329_V	1.931	1.00
309_T	312_E	1.914	1.00
143_G	154_E	1.910	1.00
440_D	494_K	1.899	1.00
483_R	491_A	1.897	1.00
285_L	327_K	1.890	1.00
212_I	229_I	1.878	1.00
363_C	370_F	1.868	1.00
273_A	289_G	1.852	1.00
314_F	318_K	1.842	1.00
399_F	446_V	1.840	1.00
100_A	265_D	1.840	1.00
93_I	100_A	1.831	1.00
157_I	218_V	1.829	1.00
501_M	515_L	1.826	1.00
213_Q	216_V	1.816	1.00
267_H	542_K	1.799	1.00
304_R	312_E	1.797	1.00
51_K	81_S	1.797	1.00
430_V	435_T	1.794	1.00
331_V	377_L	1.786	1.00
394_A	432_I	1.783	1.00
407_L	410_K	1.778	1.00
161_E	183_I	1.764	1.00
401_E	404_A	1.763	1.00
161_E	182_D	1.758	1.00
487_L	491_A	1.720	1.00
403_K	407_L	1.720	1.00
292_V	324_M	1.712	1.00
87_N	91_E	1.708	1.00
18_A	212_I	1.703	1.00
438_I	441_Q	1.703	1.00
440_D	483_R	1.701	1.00
273_A	284_V	1.679	1.00
371_R	412_K	1.679	1.00
180_T	220_V	1.667	1.00
440_D	491_A	1.662	1.00
159_V	218_V	1.657	1.00
39_E	42_R	1.657	1.00
430_V	488_V	1.654	1.00
216_V	230_D	1.652	1.00
520_L	523_F	1.648	1.00
37_E	94_S	1.646	1.00
217_T	236_V	1.638	1.00
451_I	485_I	1.635	1.00
105_K	109_S	1.632	1.00
338_G	354_F	1.619	1.00
108_S	134_T	1.618	1.00
333_T	363_C	1.609	1.00
513_P	540_L	1.607	1.00
443_A	449_F	1.601	1.00
99_N	102_F	1.599	1.00
441_Q	483_R	1.597	1.00
407_L	411_E	1.588	1.00
432_I	459_Y	1.588	1.00
428_M	442_F	1.583	1.00
390_F	403_K	1.573	1.00
104_L	137_V	1.572	1.00
113_T	116_E	1.566	1.00
507_G	525_M	1.558	1.00
513_P	543_Q	1.557	1.00
443_A	497_K	1.554	1.00
500_G	522_E	1.551	1.00
267_H	521_D	1.549	1.00
451_I	520_L	1.538	1.00
489_I	499_V	1.536	1.00
180_T	227_V	1.504	1.00
35_D	38_A	1.501	1.00
438_I	442_F	1.498	1.00
120_N	124_K	1.492	1.00
182_D	209_T	1.489	1.00
461_M	481_I	1.484	1.00
157_I	178_G	1.484	1.00
43_F	47_I	1.482	1.00
310_E	379_R	1.481	1.00
300_L	316_A	1.477	1.00
116_E	131_R	1.476	1.00
405_I	408_E	1.476	1.00
295_Y	320_V	1.470	1.00
330_V	387_K	1.463	1.00
202_V	227_V	1.443	1.00
321_L	377_L	1.438	1.00
370_F	402_A	1.437	1.00
90_K	94_S	1.429	1.00
512_I	537_I	1.425	1.00
330_V	500_G	1.423	1.00
315_D	319_T	1.415	1.00
311_D	315_D	1.414	1.00
364_L	401_E	1.412	1.00
112_V	116_E	1.408	1.00
271_L	537_I	1.408	1.00
271_L	530_I	1.399	1.00
271_L	534_R	1.392	1.00
425_E	498_W	1.390	1.00
281_V	285_L	1.381	1.00
270_E	290_E	1.381	1.00
40_V	90_K	1.378	1.00
514_I	518_L	1.368	1.00
39_E	100_A	1.361	1.00
180_T	205_T	1.359	1.00
159_V	180_T	1.358	1.00
396_V	445_E	1.358	1.00
42_R	45_E	1.355	1.00
290_E	327_K	1.346	1.00
439_A	449_F	1.346	1.00
486_T	518_L	1.344	1.00
182_D	205_T	1.343	1.00
485_I	518_L	1.342	1.00
310_E	375_R	1.338	1.00
365_E	469_R	1.323	1.00
410_K	424_I	1.315	1.00
435_T	442_F	1.311	1.00
378_L	406_L	1.307	1.00
122_Y	126_R	1.297	1.00
120_N	123_M	1.283	1.00
289_G	530_I	1.283	1.00
404_A	408_E	1.279	1.00
92_K	106_E	1.274	1.00
400_K	403_K	1.272	1.00
330_V	498_W	1.267	1.00
326_G	385_N	1.261	1.00
428_M	446_V	1.257	1.00
154_E	175_F	1.253	1.00
483_R	487_L	1.241	1.00
451_I	488_V	1.237	1.00
485_I	520_L	1.229	1.00
115_F	118_M	1.228	1.00
411_E	414_V	1.227	1.00
380_A	386_L	1.226	1.00
440_D	495_E	1.220	1.00
179_F	194_A	1.215	1.00
38_A	41_S	1.209	1.00
252_E	255_K	1.209	1.00
217_T	231_P	1.203	1.00
513_P	517_G	1.203	1.00
18_A	159_V	1.191	1.00
285_L	323_R	1.188	1.00
247_L	251_A	1.186	1.00
394_A	434_S	1.182	1.00
132_D	166_S	1.179	1.00
411_E	415_K	1.178	1.00
281_V	323_R	1.176	1.00
357_Y	469_R	1.176	1.00
310_E	372_T	1.170	1.00
377_L	388_I	1.169	1.00
236_V	240_E	1.165	1.00
207_A	211_T	1.164	1.00
157_I	220_V	1.163	1.00
432_I	462_A	1.156	1.00
272_A	291_A	1.156	1.00
489_I	520_L	1.155	1.00
489_I	523_F	1.146	1.00
479_P	508_D	1.139	1.00
505_M	511_A	1.138	1.00
282_K	323_R	1.133	1.00
230_D	233_A	1.127	1.00
389_M	450_S	1.127	1.00
378_L	410_K	1.126	1.00
221_D	224_N	1.124	1.00
119_D	124_K	1.120	1.00
45_E	49_R	1.120	1.00
483_R	486_T	1.117	1.00
390_F	426_V	1.113	1.00
405_I	409_E	1.112	1.00
120_N	126_R	1.111	1.00
228_I	231_P	1.108	1.00
58_K	74_S	1.104	0.99
39_E	46_A	1.104	0.99
273_A	530_I	1.101	0.99
396_V	400_K	1.100	0.99
350_E	467_N	1.100	0.99
17_K	154_E	1.100	0.99
148_N	151_M	1.099	0.99
381_S	421_S	1.094	0.99
434_S	480_A	1.091	0.99
438_I	483_R	1.090	0.99
278_P	316_A	1.089	0.99
460_T	481_I	1.080	0.99
461_M	478_N	1.070	0.99
145_E	214_N	1.066	0.99
234_E	238_E	1.065	0.99
406_L	426_V	1.065	0.99
516_L	537_I	1.064	0.99
407_L	426_V	1.055	0.99
55_E	59_E	1.053	0.99
228_I	232_S	1.048	0.99
153_S	156_V	1.047	0.99
251_A	254_A	1.046	0.99
91_E	95_T	1.046	0.99
421_S	424_I	1.045	0.99
281_V	284_V	1.045	0.99
245_A	248_A	1.038	0.99
252_E	535_T	1.038	0.99
319_T	323_R	1.036	0.99
221_D	226_D	1.033	0.99
403_K	447_D	1.033	0.99
48_A	52_E	1.026	0.99
121_E	124_K	1.023	0.99
403_K	426_V	1.022	0.99
268_H	290_E	1.020	0.99
333_T	388_I	1.018	0.99
216_V	229_I	1.014	0.99
283_G	286_E	1.012	0.99
102_F	106_E	1.012	0.99
271_L	523_F	1.006	0.99
98_V	106_E	1.001	0.99
168_T	197_L	0.993	0.99
487_L	490_E	0.989	0.99
94_S	249_Q	0.989	0.99
485_I	488_V	0.989	0.99
49_R	140_H	0.988	0.99
307_L	344_Y	0.984	0.99
155_E	175_F	0.984	0.99
449_F	492_A	0.983	0.99
408_E	412_K	0.979	0.99
490_E	494_K	0.979	0.99
202_V	220_V	0.979	0.99
54_L	57_I	0.978	0.99
375_R	412_K	0.975	0.99
52_E	55_E	0.974	0.99
55_E	77_L	0.973	0.99
248_A	251_A	0.972	0.99
112_V	131_R	0.969	0.99
101_E	142_L	0.963	0.99
374_L	378_L	0.961	0.99
152_I	156_V	0.961	0.99
385_N	425_E	0.959	0.99
453_T	501_M	0.958	0.99
535_T	539_K	0.955	0.99
272_A	522_E	0.951	0.98
267_H	290_E	0.951	0.98
410_K	421_S	0.950	0.98
492_A	497_K	0.940	0.98
182_D	207_A	0.940	0.98
80_L	137_V	0.939	0.98
525_M	533_A	0.938	0.98
222_G	225_G	0.934	0.98
133_V	186_R	0.933	0.98
218_V	227_V	0.931	0.98
142_L	212_I	0.930	0.98
37_E	41_S	0.928	0.98
428_M	435_T	0.928	0.98
400_K	404_A	0.922	0.98
15_I	219_I	0.921	0.98
153_S	175_F	0.919	0.98
401_E	405_I	0.918	0.98
477_Y	511_A	0.918	0.98
311_D	379_R	0.913	0.98
301_Y	313_Q	0.912	0.98
212_I	218_V	0.911	0.98
467_N	470_V	0.911	0.98
233_A	237_K	0.910	0.98
15_I	236_V	0.908	0.98
437_V	487_L	0.907	0.98
397_N	400_K	0.907	0.98
172_N	175_F	0.906	0.98
36_S	39_E	0.902	0.98
99_N	103_A	0.899	0.98
248_A	252_E	0.898	0.98
40_V	44_D	0.898	0.98
228_I	233_A	0.895	0.98
129_D	132_D	0.894	0.98
132_D	136_R	0.891	0.98
437_V	483_R	0.890	0.98
53_E	56_K	0.889	0.98
54_L	77_L	0.887	0.98
290_E	534_R	0.886	0.98
219_I	228_I	0.883	0.98
367_Q	408_E	0.883	0.98
357_Y	470_V	0.882	0.97
228_I	235_T	0.881	0.97
457_I	481_I	0.881	0.97
388_I	406_L	0.880	0.97
398_E	473_L	0.880	0.97
56_K	59_E	0.879	0.97
367_Q	401_E	0.879	0.97
355_L	459_Y	0.878	0.97
536_Q	539_K	0.878	0.97
507_G	529_S	0.875	0.97
390_F	399_F	0.875	0.97
442_F	449_F	0.874	0.97
98_V	102_F	0.871	0.97
439_A	488_V	0.870	0.97
491_A	495_E	0.863	0.97
16_A	177_K	0.861	0.97
437_V	460_T	0.859	0.97
88_P	107_T	0.855	0.97
268_H	516_L	0.854	0.97
379_R	413_L	0.846	0.97
498_W	522_E	0.839	0.97
92_K	97_S	0.839	0.97
485_I	515_L	0.839	0.97
228_I	239_Y	0.836	0.97
121_E	125_E	0.835	0.97
291_A	328_S	0.834	0.96
15_I	217_T	0.833	0.96
272_A	498_W	0.832	0.96
288_G	534_R	0.830	0.96
182_D	210_G	0.829	0.96
101_E	141_L	0.827	0.96
441_Q	444_K	0.825	0.96
92_K	110_M	0.825	0.96
42_R	141_L	0.824	0.96
182_D	208_A	0.822	0.96
397_N	478_N	0.820	0.96
145_E	149_P	0.818	0.96
53_E	136_R	0.817	0.96
279_D	303_G	0.815	0.96
285_L	324_M	0.815	0.96
351_M	466_M	0.814	0.96
307_L	345_L	0.814	0.96
104_L	138_T	0.813	0.96
513_P	536_Q	0.810	0.96
402_A	426_V	0.809	0.96
360_I	390_F	0.807	0.96
104_L	266_G	0.806	0.96
61_A	66_G	0.805	0.96
89_V	104_L	0.802	0.96
249_Q	253_W	0.802	0.96
281_V	324_M	0.802	0.96
486_T	517_G	0.802	0.96
285_L	325_E	0.801	0.96
370_F	405_I	0.799	0.96
396_V	442_F	0.797	0.95
279_D	319_T	0.797	0.95
51_K	77_L	0.795	0.95
336_I	342_L	0.792	0.95
357_Y	362_L	0.792	0.95
436_A	460_T	0.789	0.95
277_T	280_D	0.789	0.95
375_R	379_R	0.789	0.95
85_L	108_S	0.785	0.95
457_I	505_M	0.785	0.95
230_D	235_T	0.784	0.95
482_L	514_I	0.784	0.95
54_L	58_K	0.783	0.95
439_A	443_A	0.783	0.95
282_K	319_T	0.783	0.95
446_V	497_K	0.781	0.95
53_E	57_I	0.780	0.95
33_I	36_S	0.780	0.95
378_L	413_L	0.780	0.95
410_K	414_V	0.780	0.95
88_P	92_K	0.778	0.95
407_L	445_E	0.778	0.95
118_M	123_M	0.777	0.95
109_S	113_T	0.775	0.95
42_R	46_A	0.774	0.95
17_K	155_E	0.774	0.95
395_T	461_M	0.774	0.95
272_A	387_K	0.774	0.95
126_R	129_D	0.772	0.95
223_I	246_Y	0.767	0.94
50_S	53_E	0.765	0.94
396_V	438_I	0.764	0.94
350_E	353_P	0.763	0.94
276_G	280_D	0.760	0.94
331_V	386_L	0.759	0.94
34_S	41_S	0.759	0.94
348_P	469_R	0.759	0.94
476_P	505_M	0.754	0.94
501_M	523_F	0.752	0.94
162_D	190_S	0.751	0.94
152_I	155_E	0.748	0.94
50_S	136_R	0.748	0.94
251_A	255_K	0.747	0.94
394_A	463_A	0.746	0.94
212_I	216_V	0.745	0.94
441_Q	479_P	0.744	0.93
404_A	407_L	0.743	0.93
223_I	226_D	0.743	0.93
68_D	71_D	0.742	0.93
49_R	52_E	0.741	0.93
370_F	374_L	0.741	0.93
385_N	423_D	0.741	0.93
399_F	428_M	0.740	0.93
36_S	97_S	0.739	0.93
479_P	482_L	0.738	0.93
123_M	126_R	0.738	0.93
491_A	494_K	0.738	0.93
58_K	62_L	0.736	0.93
490_E	518_L	0.736	0.93
333_T	377_L	0.735	0.93
235_T	238_E	0.734	0.93
430_V	442_F	0.734	0.93
479_P	483_R	0.733	0.93
200_P	308_P	0.733	0.93
159_V	212_I	0.733	0.93
8_G	222_G	0.732	0.93
182_D	206_K	0.732	0.93
71_D	74_S	0.731	0.93
88_P	110_M	0.728	0.93
218_V	229_I	0.727	0.93
163_L	179_F	0.726	0.93
536_Q	540_L	0.726	0.93
433_P	462_A	0.725	0.93
19_Y	156_V	0.724	0.93
382_T	421_S	0.722	0.92
474_Y	479_P	0.722	0.92
488_V	491_A	0.722	0.92
87_N	90_K	0.721	0.92
51_K	55_E	0.720	0.92
479_P	510_I	0.718	0.92
310_E	314_F	0.717	0.92
430_V	436_A	0.717	0.92
41_S	44_D	0.716	0.92
113_T	117_S	0.714	0.92
489_I	493_H	0.714	0.92
436_A	439_A	0.714	0.92
531_L	534_R	0.712	0.92
141_L	231_P	0.712	0.92
525_M	530_I	0.711	0.92
432_I	435_T	0.710	0.92
59_E	62_L	0.709	0.92
451_I	499_V	0.708	0.92
179_F	201_A	0.708	0.92
44_D	48_A	0.708	0.92
491_A	497_K	0.707	0.92
110_M	113_T	0.705	0.92
397_N	401_E	0.704	0.91
163_L	168_T	0.704	0.91
57_I	78_L	0.703	0.91
334_L	369_I	0.702	0.91
137_V	140_H	0.702	0.91
32_N	36_S	0.701	0.91
100_A	266_G	0.701	0.91
428_M	449_F	0.699	0.91
390_F	393_I	0.699	0.91
127_A	130_I	0.698	0.91
385_N	421_S	0.697	0.91
101_E	266_G	0.697	0.91
52_E	56_K	0.697	0.91
321_L	331_V	0.695	0.91
85_L	89_V	0.695	0.91
533_A	536_Q	0.694	0.91
125_E	185_G	0.693	0.91
378_L	409_E	0.693	0.91
13_I	219_I	0.693	0.91
443_A	495_E	0.693	0.91
459_Y	462_A	0.692	0.91
403_K	446_V	0.692	0.91
321_L	329_V	0.690	0.91
322_E	384_G	0.689	0.91
378_L	388_I	0.689	0.91
87_N	246_Y	0.689	0.91
302_M	307_L	0.688	0.91
393_I	428_M	0.687	0.90
50_S	57_I	0.685	0.90
399_F	406_L	0.680	0.90
136_R	140_H	0.680	0.90
168_T	201_A	0.680	0.90
108_S	130_I	0.679	0.90
375_R	409_E	0.679	0.90
399_F	445_E	0.678	0.90
45_E	48_A	0.677	0.90
443_A	491_A	0.676	0.90
447_D	497_K	0.675	0.90
381_S	424_I	0.673	0.90
128_A	228_I	0.673	0.90
446_V	449_F	0.673	0.90
359_A	393_I	0.671	0.89
180_T	202_V	0.668	0.89
284_V	324_M	0.668	0.89
231_P	235_T	0.665	0.89
287_N	531_L	0.665	0.89
410_K	423_D	0.664	0.89
92_K	98_V	0.664	0.89
394_A	399_F	0.663	0.89
313_Q	317_Y	0.662	0.89
278_P	281_V	0.661	0.89
507_G	533_A	0.661	0.89
481_I	485_I	0.658	0.88
237_K	240_E	0.657	0.88
33_I	99_N	0.652	0.88
120_N	219_I	0.651	0.88
119_D	123_M	0.651	0.88
284_V	288_G	0.651	0.88
92_K	107_T	0.650	0.88
181_T	201_A	0.650	0.88
514_I	517_G	0.649	0.88
498_W	521_D	0.649	0.88
33_I	97_S	0.649	0.88
9_A	190_S	0.647	0.88
5_K	226_D	0.646	0.88
271_L	525_M	0.646	0.88
195_R	507_G	0.645	0.87
17_K	217_T	0.642	0.87
438_I	478_N	0.638	0.87
245_A	249_Q	0.636	0.87
457_I	476_P	0.636	0.87
119_D	122_Y	0.635	0.87
231_P	234_E	0.634	0.87
130_I	205_T	0.633	0.86
168_T	190_S	0.632	0.86
33_I	40_V	0.630	0.86
317_Y	373_Q	0.629	0.86
135_K	138_T	0.629	0.86
534_R	538_S	0.629	0.86
22_E	25_D	0.628	0.86
275_I	284_V	0.628	0.86
171_L	179_F	0.627	0.86
88_P	91_E	0.627	0.86
366_E	369_I	0.626	0.86
210_G	229_I	0.626	0.86
323_R	326_G	0.626	0.86
171_L	176_V	0.625	0.86
410_K	422_D	0.625	0.86
394_A	461_M	0.625	0.86
459_Y	478_N	0.624	0.86
44_D	47_I	0.624	0.86
395_T	473_L	0.623	0.86
378_L	424_I	0.623	0.86
269_V	523_F	0.622	0.86
395_T	478_N	0.622	0.86
512_I	536_Q	0.621	0.85
50_S	54_L	0.620	0.85
176_V	199_I	0.620	0.85
381_S	410_K	0.616	0.85
317_Y	377_L	0.616	0.85
66_G	70_A	0.615	0.85
107_T	250_K	0.613	0.85
249_Q	535_T	0.611	0.85
93_I	103_A	0.610	0.84
149_P	154_E	0.610	0.84
381_S	414_V	0.610	0.84
489_I	518_L	0.608	0.84
247_L	250_K	0.607	0.84
501_M	506_A	0.607	0.84
305_D	308_P	0.607	0.84
50_S	80_L	0.606	0.84
353_P	458_Q	0.605	0.84
162_D	183_I	0.605	0.84
402_A	405_I	0.604	0.84
50_S	58_K	0.602	0.84
163_L	181_T	0.600	0.83
197_L	277_T	0.599	0.83
47_I	137_V	0.599	0.83
253_W	531_L	0.599	0.83
352_N	458_Q	0.598	0.83
322_E	383_Y	0.598	0.83
399_F	403_K	0.598	0.83
449_F	497_K	0.597	0.83
410_K	426_V	0.597	0.83
374_L	409_E	0.597	0.83
181_T	203_V	0.595	0.83
28_V	31_K	0.594	0.83
168_T	181_T	0.594	0.83
457_I	475_Q	0.594	0.83
84_E	87_N	0.594	0.83
314_F	375_R	0.593	0.83
307_L	372_T	0.593	0.83
34_S	39_E	0.592	0.83
382_T	422_D	0.590	0.82
432_I	461_M	0.590	0.82
362_L	366_E	0.590	0.82
34_S	45_E	0.589	0.82
159_V	227_V	0.589	0.82
89_V	137_V	0.588	0.82
104_L	141_L	0.587	0.82
330_V	448_F	0.587	0.82
399_F	402_A	0.586	0.82
73_F	76_H	0.585	0.82
32_N	65_L	0.584	0.82
107_T	110_M	0.584	0.82
102_F	105_K	0.583	0.82
122_Y	125_E	0.583	0.82
427_G	448_F	0.583	0.82
121_E	126_R	0.583	0.82
29_E	32_N	0.582	0.82
205_T	227_V	0.582	0.82
28_V	32_N	0.581	0.81
62_L	67_Q	0.580	0.81
149_P	152_I	0.580	0.81
484_L	488_V	0.580	0.81
59_E	63_K	0.580	0.81
37_E	40_V	0.579	0.81
516_L	542_K	0.578	0.81
268_H	541_S	0.578	0.81
58_K	70_A	0.578	0.81
31_K	99_N	0.577	0.81
407_L	414_V	0.577	0.81
504_E	526_S	0.577	0.81
119_D	126_R	0.576	0.81
250_K	253_W	0.576	0.81
139_G	142_L	0.575	0.81
133_V	136_R	0.574	0.81
501_M	511_A	0.574	0.81
438_I	480_A	0.574	0.81
328_S	425_E	0.573	0.81
395_T	463_A	0.573	0.81
272_A	330_V	0.573	0.81
234_E	237_K	0.573	0.81
230_D	234_E	0.570	0.80
333_T	402_A	0.569	0.80
235_T	239_Y	0.569	0.80
168_T	179_F	0.569	0.80
48_A	51_K	0.569	0.80
9_A	203_V	0.568	0.80
488_V	497_K	0.568	0.80
131_R	226_D	0.568	0.80
346_Q	362_L	0.567	0.80
374_L	402_A	0.567	0.80
396_V	444_K	0.567	0.80
477_Y	514_I	0.566	0.80
470_V	473_L	0.566	0.80
402_A	406_L	0.566	0.80
55_E	58_K	0.565	0.80
46_A	54_L	0.565	0.80
202_V	225_G	0.565	0.80
387_K	498_W	0.565	0.80
136_R	139_G	0.565	0.80
317_Y	388_I	0.564	0.80
441_Q	445_E	0.564	0.80
22_E	214_N	0.563	0.79
341_E	349_K	0.563	0.79
297_T	313_Q	0.562	0.79
219_I	231_P	0.562	0.79
321_L	385_N	0.561	0.79
31_K	34_S	0.561	0.79
451_I	489_I	0.559	0.79
508_D	512_I	0.559	0.79
276_G	295_Y	0.558	0.79
325_E	329_V	0.557	0.79
76_H	80_L	0.556	0.79
36_S	40_V	0.556	0.79
306_Q	309_T	0.555	0.78
364_L	402_A	0.555	0.78
281_V	329_V	0.555	0.78
163_L	190_S	0.554	0.78
207_A	210_G	0.553	0.78
328_S	385_N	0.552	0.78
220_V	227_V	0.551	0.78
250_K	254_A	0.550	0.78
319_T	322_E	0.550	0.78
46_A	141_L	0.549	0.78
202_V	205_T	0.549	0.78
39_E	47_I	0.549	0.78
334_L	362_L	0.547	0.77
395_T	438_I	0.544	0.77
265_D	517_G	0.544	0.77
137_V	142_L	0.543	0.77
66_G	69_K	0.543	0.77
7_I	10_S	0.542	0.77
351_M	468_E	0.541	0.77
195_R	504_E	0.539	0.76
86_L	89_V	0.539	0.76
278_P	319_T	0.538	0.76
159_V	209_T	0.537	0.76
179_F	190_S	0.537	0.76
127_A	229_I	0.537	0.76
436_A	488_V	0.536	0.76
36_S	94_S	0.536	0.76
353_P	356_G	0.535	0.76
482_L	511_A	0.535	0.76
10_S	201_A	0.534	0.76
132_D	137_V	0.533	0.76
304_R	308_P	0.533	0.76
525_M	529_S	0.533	0.76
19_Y	214_N	0.532	0.76
283_G	287_N	0.531	0.75
280_D	284_V	0.531	0.75
382_T	414_V	0.530	0.75
79_V	130_I	0.529	0.75
150_S	177_K	0.527	0.75
443_A	492_A	0.527	0.75
509_E	533_A	0.527	0.75
122_Y	129_D	0.526	0.75
430_V	492_A	0.524	0.74
28_V	34_S	0.524	0.74
516_L	523_F	0.524	0.74
396_V	399_F	0.523	0.74
41_S	46_A	0.523	0.74
40_V	43_F	0.522	0.74
30_K	102_F	0.522	0.74
169_A	193_M	0.521	0.74
41_S	218_V	0.521	0.74
270_E	498_W	0.521	0.74
367_Q	371_R	0.520	0.74
449_F	488_V	0.520	0.74
191_A	201_A	0.520	0.74
402_A	409_E	0.518	0.74
388_I	424_I	0.518	0.74
466_M	501_M	0.518	0.74
167_D	181_T	0.517	0.73
94_S	97_S	0.517	0.73
147_P	151_M	0.517	0.73
195_R	292_V	0.516	0.73
136_R	142_L	0.516	0.73
412_K	415_K	0.515	0.73
321_L	382_T	0.515	0.73
439_A	511_A	0.515	0.73
368_E	372_T	0.515	0.73
28_V	40_V	0.515	0.73
120_N	129_D	0.515	0.73
30_K	98_V	0.515	0.73
482_L	517_G	0.515	0.73
461_M	480_A	0.514	0.73
89_V	107_T	0.514	0.73
361_R	427_G	0.514	0.73
273_A	281_V	0.513	0.73
502_C	524_S	0.512	0.73
511_A	515_L	0.512	0.73
132_D	142_L	0.509	0.72
270_E	385_N	0.508	0.72
486_T	489_I	0.507	0.72
367_Q	405_I	0.507	0.72
246_Y	249_Q	0.506	0.72
145_E	148_N	0.506	0.72
15_I	240_E	0.505	0.72
266_G	541_S	0.504	0.72
158_I	179_F	0.504	0.72
516_L	541_S	0.504	0.72
392_M	462_A	0.504	0.72
150_S	155_E	0.503	0.71
129_D	137_V	0.503	0.71
378_L	382_T	0.503	0.71
500_G	521_D	0.503	0.71
336_I	344_Y	0.502	0.71
521_D	542_K	0.501	0.71
363_C	402_A	0.501	0.71
339_D	466_M	0.500	0.71
403_K	410_K	0.500	0.71
136_R	192_I	0.500	0.71

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2wqdA	2	0.9965	100	0.179	Contact Map
2hwgA	2	0.9947	100	0.185	Contact Map
1kblA	2	0.8667	100	0.339	Contact Map
2x0sA	2	0.9175	100	0.34	Contact Map
1vbgA	2	0.8632	100	0.342	Contact Map
2olsA	2	0.7491	100	0.417	Contact Map
2xz9A	2	0.5526	100	0.543	Contact Map
1zymA	2	0.4316	100	0.683	Contact Map
4l9zA	5	0.4807	100	0.779	Contact Map
3qqwA	3	0.4684	100	0.78	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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