GREMLIN Database
PT1 - Phosphoenolpyruvate-protein phosphotransferase
UniProt: P08838 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 570 (518)
Sequences: 6063 (3541)
Seq/√Len: 155.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
486_T490_E5.1831.00
178_G220_V5.1281.00
400_K445_E5.0361.00
314_F383_Y3.7791.00
493_H521_D3.6481.00
436_A484_L3.0301.00
371_R408_E2.9161.00
324_M329_V2.9051.00
492_A499_V2.8871.00
387_K425_E2.8321.00
357_Y365_E2.8161.00
232_S235_T2.8141.00
318_K383_Y2.7731.00
321_L386_L2.7561.00
44_D90_K2.7531.00
460_T484_L2.5941.00
155_E177_K2.5941.00
501_M520_L2.5861.00
314_F379_R2.5501.00
439_A491_A2.4931.00
371_R409_E2.4771.00
318_K322_E2.4521.00
409_E412_K2.4291.00
377_L386_L2.4121.00
437_V484_L2.4091.00
403_K445_E2.3781.00
371_R405_I2.2731.00
390_F402_A2.2631.00
18_A218_V2.2501.00
541_S544_E2.2451.00
40_V94_S2.2361.00
360_I393_I2.2061.00
444_K495_E2.2031.00
414_V422_D2.1911.00
42_R101_E2.1831.00
282_K286_E2.1321.00
202_V222_G2.1301.00
208_A212_I2.1141.00
43_F89_V2.1011.00
219_I239_Y2.0951.00
333_T390_F2.0951.00
41_S45_E2.0941.00
488_V499_V2.0901.00
414_V421_S2.0651.00
53_E140_H2.0371.00
360_I402_A2.0351.00
374_L406_L2.0161.00
50_S140_H2.0151.00
390_F406_L2.0121.00
512_I533_A1.9941.00
269_V516_L1.9931.00
447_D494_K1.9851.00
328_S387_K1.9811.00
284_V289_G1.9791.00
320_V329_V1.9311.00
309_T312_E1.9141.00
143_G154_E1.9101.00
440_D494_K1.8991.00
483_R491_A1.8971.00
285_L327_K1.8901.00
212_I229_I1.8781.00
363_C370_F1.8681.00
273_A289_G1.8521.00
314_F318_K1.8421.00
399_F446_V1.8401.00
100_A265_D1.8401.00
93_I100_A1.8311.00
157_I218_V1.8291.00
501_M515_L1.8261.00
213_Q216_V1.8161.00
267_H542_K1.7991.00
304_R312_E1.7971.00
51_K81_S1.7971.00
430_V435_T1.7941.00
331_V377_L1.7861.00
394_A432_I1.7831.00
407_L410_K1.7781.00
161_E183_I1.7641.00
401_E404_A1.7631.00
161_E182_D1.7581.00
487_L491_A1.7201.00
403_K407_L1.7201.00
292_V324_M1.7121.00
87_N91_E1.7081.00
18_A212_I1.7031.00
438_I441_Q1.7031.00
440_D483_R1.7011.00
273_A284_V1.6791.00
371_R412_K1.6791.00
180_T220_V1.6671.00
440_D491_A1.6621.00
159_V218_V1.6571.00
39_E42_R1.6571.00
430_V488_V1.6541.00
216_V230_D1.6521.00
520_L523_F1.6481.00
37_E94_S1.6461.00
217_T236_V1.6381.00
451_I485_I1.6351.00
105_K109_S1.6321.00
338_G354_F1.6191.00
108_S134_T1.6181.00
333_T363_C1.6091.00
513_P540_L1.6071.00
443_A449_F1.6011.00
99_N102_F1.5991.00
441_Q483_R1.5971.00
407_L411_E1.5881.00
432_I459_Y1.5881.00
428_M442_F1.5831.00
390_F403_K1.5731.00
104_L137_V1.5721.00
113_T116_E1.5661.00
507_G525_M1.5581.00
513_P543_Q1.5571.00
443_A497_K1.5541.00
500_G522_E1.5511.00
267_H521_D1.5491.00
451_I520_L1.5381.00
489_I499_V1.5361.00
180_T227_V1.5041.00
35_D38_A1.5011.00
438_I442_F1.4981.00
120_N124_K1.4921.00
182_D209_T1.4891.00
461_M481_I1.4841.00
157_I178_G1.4841.00
43_F47_I1.4821.00
310_E379_R1.4811.00
300_L316_A1.4771.00
116_E131_R1.4761.00
405_I408_E1.4761.00
295_Y320_V1.4701.00
330_V387_K1.4631.00
202_V227_V1.4431.00
321_L377_L1.4381.00
370_F402_A1.4371.00
90_K94_S1.4291.00
512_I537_I1.4251.00
330_V500_G1.4231.00
315_D319_T1.4151.00
311_D315_D1.4141.00
364_L401_E1.4121.00
112_V116_E1.4081.00
271_L537_I1.4081.00
271_L530_I1.3991.00
271_L534_R1.3921.00
425_E498_W1.3901.00
281_V285_L1.3811.00
270_E290_E1.3811.00
40_V90_K1.3781.00
514_I518_L1.3681.00
39_E100_A1.3611.00
180_T205_T1.3591.00
159_V180_T1.3581.00
396_V445_E1.3581.00
42_R45_E1.3551.00
290_E327_K1.3461.00
439_A449_F1.3461.00
486_T518_L1.3441.00
182_D205_T1.3431.00
485_I518_L1.3421.00
310_E375_R1.3381.00
365_E469_R1.3231.00
410_K424_I1.3151.00
435_T442_F1.3111.00
378_L406_L1.3071.00
122_Y126_R1.2971.00
120_N123_M1.2831.00
289_G530_I1.2831.00
404_A408_E1.2791.00
92_K106_E1.2741.00
400_K403_K1.2721.00
330_V498_W1.2671.00
326_G385_N1.2611.00
428_M446_V1.2571.00
154_E175_F1.2531.00
483_R487_L1.2411.00
451_I488_V1.2371.00
485_I520_L1.2291.00
115_F118_M1.2281.00
411_E414_V1.2271.00
380_A386_L1.2261.00
440_D495_E1.2201.00
179_F194_A1.2151.00
38_A41_S1.2091.00
252_E255_K1.2091.00
217_T231_P1.2031.00
513_P517_G1.2031.00
18_A159_V1.1911.00
285_L323_R1.1881.00
247_L251_A1.1861.00
394_A434_S1.1821.00
132_D166_S1.1791.00
411_E415_K1.1781.00
281_V323_R1.1761.00
357_Y469_R1.1761.00
310_E372_T1.1701.00
377_L388_I1.1691.00
236_V240_E1.1651.00
207_A211_T1.1641.00
157_I220_V1.1631.00
432_I462_A1.1561.00
272_A291_A1.1561.00
489_I520_L1.1551.00
489_I523_F1.1461.00
479_P508_D1.1391.00
505_M511_A1.1381.00
282_K323_R1.1331.00
230_D233_A1.1271.00
389_M450_S1.1271.00
378_L410_K1.1261.00
221_D224_N1.1241.00
119_D124_K1.1201.00
45_E49_R1.1201.00
483_R486_T1.1171.00
390_F426_V1.1131.00
405_I409_E1.1121.00
120_N126_R1.1111.00
228_I231_P1.1081.00
58_K74_S1.1040.99
39_E46_A1.1040.99
273_A530_I1.1010.99
396_V400_K1.1000.99
350_E467_N1.1000.99
17_K154_E1.1000.99
148_N151_M1.0990.99
381_S421_S1.0940.99
434_S480_A1.0910.99
438_I483_R1.0900.99
278_P316_A1.0890.99
460_T481_I1.0800.99
461_M478_N1.0700.99
145_E214_N1.0660.99
234_E238_E1.0650.99
406_L426_V1.0650.99
516_L537_I1.0640.99
407_L426_V1.0550.99
55_E59_E1.0530.99
228_I232_S1.0480.99
153_S156_V1.0470.99
251_A254_A1.0460.99
91_E95_T1.0460.99
421_S424_I1.0450.99
281_V284_V1.0450.99
245_A248_A1.0380.99
252_E535_T1.0380.99
319_T323_R1.0360.99
221_D226_D1.0330.99
403_K447_D1.0330.99
48_A52_E1.0260.99
121_E124_K1.0230.99
403_K426_V1.0220.99
268_H290_E1.0200.99
333_T388_I1.0180.99
216_V229_I1.0140.99
283_G286_E1.0120.99
102_F106_E1.0120.99
271_L523_F1.0060.99
98_V106_E1.0010.99
168_T197_L0.9930.99
487_L490_E0.9890.99
94_S249_Q0.9890.99
485_I488_V0.9890.99
49_R140_H0.9880.99
307_L344_Y0.9840.99
155_E175_F0.9840.99
449_F492_A0.9830.99
408_E412_K0.9790.99
490_E494_K0.9790.99
202_V220_V0.9790.99
54_L57_I0.9780.99
375_R412_K0.9750.99
52_E55_E0.9740.99
55_E77_L0.9730.99
248_A251_A0.9720.99
112_V131_R0.9690.99
101_E142_L0.9630.99
374_L378_L0.9610.99
152_I156_V0.9610.99
385_N425_E0.9590.99
453_T501_M0.9580.99
535_T539_K0.9550.99
272_A522_E0.9510.98
267_H290_E0.9510.98
410_K421_S0.9500.98
492_A497_K0.9400.98
182_D207_A0.9400.98
80_L137_V0.9390.98
525_M533_A0.9380.98
222_G225_G0.9340.98
133_V186_R0.9330.98
218_V227_V0.9310.98
142_L212_I0.9300.98
37_E41_S0.9280.98
428_M435_T0.9280.98
400_K404_A0.9220.98
15_I219_I0.9210.98
153_S175_F0.9190.98
401_E405_I0.9180.98
477_Y511_A0.9180.98
311_D379_R0.9130.98
301_Y313_Q0.9120.98
212_I218_V0.9110.98
467_N470_V0.9110.98
233_A237_K0.9100.98
15_I236_V0.9080.98
437_V487_L0.9070.98
397_N400_K0.9070.98
172_N175_F0.9060.98
36_S39_E0.9020.98
99_N103_A0.8990.98
248_A252_E0.8980.98
40_V44_D0.8980.98
228_I233_A0.8950.98
129_D132_D0.8940.98
132_D136_R0.8910.98
437_V483_R0.8900.98
53_E56_K0.8890.98
54_L77_L0.8870.98
290_E534_R0.8860.98
219_I228_I0.8830.98
367_Q408_E0.8830.98
357_Y470_V0.8820.97
228_I235_T0.8810.97
457_I481_I0.8810.97
388_I406_L0.8800.97
398_E473_L0.8800.97
56_K59_E0.8790.97
367_Q401_E0.8790.97
355_L459_Y0.8780.97
536_Q539_K0.8780.97
507_G529_S0.8750.97
390_F399_F0.8750.97
442_F449_F0.8740.97
98_V102_F0.8710.97
439_A488_V0.8700.97
491_A495_E0.8630.97
16_A177_K0.8610.97
437_V460_T0.8590.97
88_P107_T0.8550.97
268_H516_L0.8540.97
379_R413_L0.8460.97
498_W522_E0.8390.97
92_K97_S0.8390.97
485_I515_L0.8390.97
228_I239_Y0.8360.97
121_E125_E0.8350.97
291_A328_S0.8340.96
15_I217_T0.8330.96
272_A498_W0.8320.96
288_G534_R0.8300.96
182_D210_G0.8290.96
101_E141_L0.8270.96
441_Q444_K0.8250.96
92_K110_M0.8250.96
42_R141_L0.8240.96
182_D208_A0.8220.96
397_N478_N0.8200.96
145_E149_P0.8180.96
53_E136_R0.8170.96
279_D303_G0.8150.96
285_L324_M0.8150.96
351_M466_M0.8140.96
307_L345_L0.8140.96
104_L138_T0.8130.96
513_P536_Q0.8100.96
402_A426_V0.8090.96
360_I390_F0.8070.96
104_L266_G0.8060.96
61_A66_G0.8050.96
89_V104_L0.8020.96
249_Q253_W0.8020.96
281_V324_M0.8020.96
486_T517_G0.8020.96
285_L325_E0.8010.96
370_F405_I0.7990.96
396_V442_F0.7970.95
279_D319_T0.7970.95
51_K77_L0.7950.95
336_I342_L0.7920.95
357_Y362_L0.7920.95
436_A460_T0.7890.95
277_T280_D0.7890.95
375_R379_R0.7890.95
85_L108_S0.7850.95
457_I505_M0.7850.95
230_D235_T0.7840.95
482_L514_I0.7840.95
54_L58_K0.7830.95
439_A443_A0.7830.95
282_K319_T0.7830.95
446_V497_K0.7810.95
53_E57_I0.7800.95
33_I36_S0.7800.95
378_L413_L0.7800.95
410_K414_V0.7800.95
88_P92_K0.7780.95
407_L445_E0.7780.95
118_M123_M0.7770.95
109_S113_T0.7750.95
42_R46_A0.7740.95
17_K155_E0.7740.95
395_T461_M0.7740.95
272_A387_K0.7740.95
126_R129_D0.7720.95
223_I246_Y0.7670.94
50_S53_E0.7650.94
396_V438_I0.7640.94
350_E353_P0.7630.94
276_G280_D0.7600.94
331_V386_L0.7590.94
34_S41_S0.7590.94
348_P469_R0.7590.94
476_P505_M0.7540.94
501_M523_F0.7520.94
162_D190_S0.7510.94
152_I155_E0.7480.94
50_S136_R0.7480.94
251_A255_K0.7470.94
394_A463_A0.7460.94
212_I216_V0.7450.94
441_Q479_P0.7440.93
404_A407_L0.7430.93
223_I226_D0.7430.93
68_D71_D0.7420.93
49_R52_E0.7410.93
370_F374_L0.7410.93
385_N423_D0.7410.93
399_F428_M0.7400.93
36_S97_S0.7390.93
479_P482_L0.7380.93
123_M126_R0.7380.93
491_A494_K0.7380.93
58_K62_L0.7360.93
490_E518_L0.7360.93
333_T377_L0.7350.93
235_T238_E0.7340.93
430_V442_F0.7340.93
479_P483_R0.7330.93
200_P308_P0.7330.93
159_V212_I0.7330.93
8_G222_G0.7320.93
182_D206_K0.7320.93
71_D74_S0.7310.93
88_P110_M0.7280.93
218_V229_I0.7270.93
163_L179_F0.7260.93
536_Q540_L0.7260.93
433_P462_A0.7250.93
19_Y156_V0.7240.93
382_T421_S0.7220.92
474_Y479_P0.7220.92
488_V491_A0.7220.92
87_N90_K0.7210.92
51_K55_E0.7200.92
479_P510_I0.7180.92
310_E314_F0.7170.92
430_V436_A0.7170.92
41_S44_D0.7160.92
113_T117_S0.7140.92
489_I493_H0.7140.92
436_A439_A0.7140.92
531_L534_R0.7120.92
141_L231_P0.7120.92
525_M530_I0.7110.92
432_I435_T0.7100.92
59_E62_L0.7090.92
451_I499_V0.7080.92
179_F201_A0.7080.92
44_D48_A0.7080.92
491_A497_K0.7070.92
110_M113_T0.7050.92
397_N401_E0.7040.91
163_L168_T0.7040.91
57_I78_L0.7030.91
334_L369_I0.7020.91
137_V140_H0.7020.91
32_N36_S0.7010.91
100_A266_G0.7010.91
428_M449_F0.6990.91
390_F393_I0.6990.91
127_A130_I0.6980.91
385_N421_S0.6970.91
101_E266_G0.6970.91
52_E56_K0.6970.91
321_L331_V0.6950.91
85_L89_V0.6950.91
533_A536_Q0.6940.91
125_E185_G0.6930.91
378_L409_E0.6930.91
13_I219_I0.6930.91
443_A495_E0.6930.91
459_Y462_A0.6920.91
403_K446_V0.6920.91
321_L329_V0.6900.91
322_E384_G0.6890.91
378_L388_I0.6890.91
87_N246_Y0.6890.91
302_M307_L0.6880.91
393_I428_M0.6870.90
50_S57_I0.6850.90
399_F406_L0.6800.90
136_R140_H0.6800.90
168_T201_A0.6800.90
108_S130_I0.6790.90
375_R409_E0.6790.90
399_F445_E0.6780.90
45_E48_A0.6770.90
443_A491_A0.6760.90
447_D497_K0.6750.90
381_S424_I0.6730.90
128_A228_I0.6730.90
446_V449_F0.6730.90
359_A393_I0.6710.89
180_T202_V0.6680.89
284_V324_M0.6680.89
231_P235_T0.6650.89
287_N531_L0.6650.89
410_K423_D0.6640.89
92_K98_V0.6640.89
394_A399_F0.6630.89
313_Q317_Y0.6620.89
278_P281_V0.6610.89
507_G533_A0.6610.89
481_I485_I0.6580.88
237_K240_E0.6570.88
33_I99_N0.6520.88
120_N219_I0.6510.88
119_D123_M0.6510.88
284_V288_G0.6510.88
92_K107_T0.6500.88
181_T201_A0.6500.88
514_I517_G0.6490.88
498_W521_D0.6490.88
33_I97_S0.6490.88
9_A190_S0.6470.88
5_K226_D0.6460.88
271_L525_M0.6460.88
195_R507_G0.6450.87
17_K217_T0.6420.87
438_I478_N0.6380.87
245_A249_Q0.6360.87
457_I476_P0.6360.87
119_D122_Y0.6350.87
231_P234_E0.6340.87
130_I205_T0.6330.86
168_T190_S0.6320.86
33_I40_V0.6300.86
317_Y373_Q0.6290.86
135_K138_T0.6290.86
534_R538_S0.6290.86
22_E25_D0.6280.86
275_I284_V0.6280.86
171_L179_F0.6270.86
88_P91_E0.6270.86
366_E369_I0.6260.86
210_G229_I0.6260.86
323_R326_G0.6260.86
171_L176_V0.6250.86
410_K422_D0.6250.86
394_A461_M0.6250.86
459_Y478_N0.6240.86
44_D47_I0.6240.86
395_T473_L0.6230.86
378_L424_I0.6230.86
269_V523_F0.6220.86
395_T478_N0.6220.86
512_I536_Q0.6210.85
50_S54_L0.6200.85
176_V199_I0.6200.85
381_S410_K0.6160.85
317_Y377_L0.6160.85
66_G70_A0.6150.85
107_T250_K0.6130.85
249_Q535_T0.6110.85
93_I103_A0.6100.84
149_P154_E0.6100.84
381_S414_V0.6100.84
489_I518_L0.6080.84
247_L250_K0.6070.84
501_M506_A0.6070.84
305_D308_P0.6070.84
50_S80_L0.6060.84
353_P458_Q0.6050.84
162_D183_I0.6050.84
402_A405_I0.6040.84
50_S58_K0.6020.84
163_L181_T0.6000.83
197_L277_T0.5990.83
47_I137_V0.5990.83
253_W531_L0.5990.83
352_N458_Q0.5980.83
322_E383_Y0.5980.83
399_F403_K0.5980.83
449_F497_K0.5970.83
410_K426_V0.5970.83
374_L409_E0.5970.83
181_T203_V0.5950.83
28_V31_K0.5940.83
168_T181_T0.5940.83
457_I475_Q0.5940.83
84_E87_N0.5940.83
314_F375_R0.5930.83
307_L372_T0.5930.83
34_S39_E0.5920.83
382_T422_D0.5900.82
432_I461_M0.5900.82
362_L366_E0.5900.82
34_S45_E0.5890.82
159_V227_V0.5890.82
89_V137_V0.5880.82
104_L141_L0.5870.82
330_V448_F0.5870.82
399_F402_A0.5860.82
73_F76_H0.5850.82
32_N65_L0.5840.82
107_T110_M0.5840.82
102_F105_K0.5830.82
122_Y125_E0.5830.82
427_G448_F0.5830.82
121_E126_R0.5830.82
29_E32_N0.5820.82
205_T227_V0.5820.82
28_V32_N0.5810.81
62_L67_Q0.5800.81
149_P152_I0.5800.81
484_L488_V0.5800.81
59_E63_K0.5800.81
37_E40_V0.5790.81
516_L542_K0.5780.81
268_H541_S0.5780.81
58_K70_A0.5780.81
31_K99_N0.5770.81
407_L414_V0.5770.81
504_E526_S0.5770.81
119_D126_R0.5760.81
250_K253_W0.5760.81
139_G142_L0.5750.81
133_V136_R0.5740.81
501_M511_A0.5740.81
438_I480_A0.5740.81
328_S425_E0.5730.81
395_T463_A0.5730.81
272_A330_V0.5730.81
234_E237_K0.5730.81
230_D234_E0.5700.80
333_T402_A0.5690.80
235_T239_Y0.5690.80
168_T179_F0.5690.80
48_A51_K0.5690.80
9_A203_V0.5680.80
488_V497_K0.5680.80
131_R226_D0.5680.80
346_Q362_L0.5670.80
374_L402_A0.5670.80
396_V444_K0.5670.80
477_Y514_I0.5660.80
470_V473_L0.5660.80
402_A406_L0.5660.80
55_E58_K0.5650.80
46_A54_L0.5650.80
202_V225_G0.5650.80
387_K498_W0.5650.80
136_R139_G0.5650.80
317_Y388_I0.5640.80
441_Q445_E0.5640.80
22_E214_N0.5630.79
341_E349_K0.5630.79
297_T313_Q0.5620.79
219_I231_P0.5620.79
321_L385_N0.5610.79
31_K34_S0.5610.79
451_I489_I0.5590.79
508_D512_I0.5590.79
276_G295_Y0.5580.79
325_E329_V0.5570.79
76_H80_L0.5560.79
36_S40_V0.5560.79
306_Q309_T0.5550.78
364_L402_A0.5550.78
281_V329_V0.5550.78
163_L190_S0.5540.78
207_A210_G0.5530.78
328_S385_N0.5520.78
220_V227_V0.5510.78
250_K254_A0.5500.78
319_T322_E0.5500.78
46_A141_L0.5490.78
202_V205_T0.5490.78
39_E47_I0.5490.78
334_L362_L0.5470.77
395_T438_I0.5440.77
265_D517_G0.5440.77
137_V142_L0.5430.77
66_G69_K0.5430.77
7_I10_S0.5420.77
351_M468_E0.5410.77
195_R504_E0.5390.76
86_L89_V0.5390.76
278_P319_T0.5380.76
159_V209_T0.5370.76
179_F190_S0.5370.76
127_A229_I0.5370.76
436_A488_V0.5360.76
36_S94_S0.5360.76
353_P356_G0.5350.76
482_L511_A0.5350.76
10_S201_A0.5340.76
132_D137_V0.5330.76
304_R308_P0.5330.76
525_M529_S0.5330.76
19_Y214_N0.5320.76
283_G287_N0.5310.75
280_D284_V0.5310.75
382_T414_V0.5300.75
79_V130_I0.5290.75
150_S177_K0.5270.75
443_A492_A0.5270.75
509_E533_A0.5270.75
122_Y129_D0.5260.75
430_V492_A0.5240.74
28_V34_S0.5240.74
516_L523_F0.5240.74
396_V399_F0.5230.74
41_S46_A0.5230.74
40_V43_F0.5220.74
30_K102_F0.5220.74
169_A193_M0.5210.74
41_S218_V0.5210.74
270_E498_W0.5210.74
367_Q371_R0.5200.74
449_F488_V0.5200.74
191_A201_A0.5200.74
402_A409_E0.5180.74
388_I424_I0.5180.74
466_M501_M0.5180.74
167_D181_T0.5170.73
94_S97_S0.5170.73
147_P151_M0.5170.73
195_R292_V0.5160.73
136_R142_L0.5160.73
412_K415_K0.5150.73
321_L382_T0.5150.73
439_A511_A0.5150.73
368_E372_T0.5150.73
28_V40_V0.5150.73
120_N129_D0.5150.73
30_K98_V0.5150.73
482_L517_G0.5150.73
461_M480_A0.5140.73
89_V107_T0.5140.73
361_R427_G0.5140.73
273_A281_V0.5130.73
502_C524_S0.5120.73
511_A515_L0.5120.73
132_D142_L0.5090.72
270_E385_N0.5080.72
486_T489_I0.5070.72
367_Q405_I0.5070.72
246_Y249_Q0.5060.72
145_E148_N0.5060.72
15_I240_E0.5050.72
266_G541_S0.5040.72
158_I179_F0.5040.72
516_L541_S0.5040.72
392_M462_A0.5040.72
150_S155_E0.5030.71
129_D137_V0.5030.71
378_L382_T0.5030.71
500_G521_D0.5030.71
336_I344_Y0.5020.71
521_D542_K0.5010.71
363_C402_A0.5010.71
339_D466_M0.5000.71
403_K410_K0.5000.71
136_R192_I0.5000.71
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2wqdA 2 0.9965 100 0.179 Contact Map
2hwgA 2 0.9947 100 0.185 Contact Map
1kblA 2 0.8667 100 0.339 Contact Map
2x0sA 2 0.9175 100 0.34 Contact Map
1vbgA 2 0.8632 100 0.342 Contact Map
2olsA 2 0.7491 100 0.417 Contact Map
2xz9A 2 0.5526 100 0.543 Contact Map
1zymA 2 0.4316 100 0.683 Contact Map
4l9zA 5 0.4807 100 0.779 Contact Map
3qqwA 3 0.4684 100 0.78 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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