SDHA - BACSU - GREMLIN Contacts

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SDHA - Succinate dehydrogenase flavoprotein subunit

UniProt:	P08065	Sequences: MSQSSIIVVGGGLAGLMATIKAAESGMAVKLFSIVPVKRSHSVCAQGGINGAVNTKGEGDSPWEHFDDTVYGGDFLANQPPVKAMCEAAPSIIHLLDRMGVMFNRTPEGLLDFRRFGGTQHHRTAYAGATTGQQLLYALDEQVRRYEVAGLVTKYEGWEFLGAVLDDDRTCRGIVAQNLTNMQIESFRSDAVIMATGGPGIIFGKSTNSMINTGSAASIVYQQGAYYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRVWTYKDGKPWYFLEEKYPAYGNLVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPKELDIKLGGIIEIYEKFMGDDPRKLPMKIFPAVHYSMGGLWVDYDQMTNIPGLFAAGECDYSMHGGNRLGANSLLSAIYGGMVAGPNAVKYVNGLESSAEDMSSSLFDAHVKKEEEKWADIMSMDGTENAYVLHKELGEWMTANVTVVRHNDKLLKTDDKIQELMERFKKININDTTKWSNQGAMFTRQFSNMLQLARVITLGAYNRNESRGAHYKPDYPERNDDEWLKTTMAKHVSPYEAPEFEYQDVDVSLITPRKRDYSKKKVAK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	586 (512)
Sequences:	5416 (2710)
Seq/√Len:	119.7

ECOLI - FRDA SDHA NADB
BACSU - SDHA NADB
HALSA - Q9HQ66 NADB
SULSO - Q97W79 NADB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
541_N	544_E	4.611	1.00
276_Y	279_Y	4.043	1.00
7_I	174_I	3.937	1.00
361_D	365_M	3.892	1.00
160_F	219_I	3.437	1.00
83_K	87_E	3.323	1.00
267_K	274_E	3.266	1.00
263_Y	267_K	3.241	1.00
77_A	82_V	3.208	1.00
4_S	30_K	3.155	1.00
463_V	519_T	2.985	1.00
85_M	381_M	2.955	1.00
469_N	526_N	2.892	1.00
18_A	193_I	2.858	1.00
483_M	516_R	2.842	1.00
462_N	474_K	2.736	1.00
249_M	253_A	2.636	1.00
270_Y	281_N	2.600	1.00
273_E	280_G	2.593	1.00
372_F	405_N	2.583	1.00
155_Y	187_F	2.498	1.00
469_N	473_L	2.492	1.00
263_Y	295_V	2.473	1.00
88_A	401_V	2.426	1.00
142_Q	145_R	2.410	1.00
28_A	153_T	2.400	1.00
9_V	174_I	2.391	1.00
178_N	181_N	2.354	1.00
476_D	519_T	2.353	1.00
454_E	478_K	2.353	1.00
526_N	537_Y	2.345	1.00
221_Y	517_V	2.340	1.00
468_H	535_P	2.309	1.00
13_L	395_A	2.271	1.00
358_L	377_C	2.239	1.00
30_K	155_Y	2.239	1.00
18_A	374_A	2.222	1.00
473_L	523_Y	2.189	1.00
480_Q	516_R	2.166	1.00
22_A	406_A	2.145	1.00
84_A	401_V	2.122	1.00
365_M	405_N	2.096	1.00
64_E	121_H	2.087	1.00
463_V	475_T	2.086	1.00
3_Q	188_R	2.073	1.00
162_G	222_Q	2.067	1.00
32_F	176_A	2.052	1.00
468_H	471_K	2.026	1.00
13_L	42_S	2.024	1.00
217_A	227_Y	2.021	1.00
261_W	344_P	2.016	1.00
373_A	377_C	2.016	1.00
5_S	190_D	1.989	1.00
194_M	358_L	1.988	1.00
85_M	398_G	1.985	1.00
261_W	314_S	1.980	1.00
318_P	322_D	1.973	1.00
22_A	403_G	1.965	1.00
292_I	309_V	1.944	1.00
239_A	350_A	1.929	1.00
134_Q	137_Y	1.912	1.00
314_S	344_P	1.882	1.00
259_R	270_Y	1.865	1.00
253_A	258_G	1.862	1.00
176_A	187_F	1.856	1.00
30_K	187_F	1.853	1.00
194_M	377_C	1.850	1.00
479_I	519_T	1.839	1.00
366_T	373_A	1.819	1.00
463_V	472_L	1.814	1.00
458_W	475_T	1.812	1.00
193_I	406_A	1.804	1.00
226_Y	367_N	1.801	1.00
329_I	333_E	1.795	1.00
106_T	110_L	1.768	1.00
459_M	463_V	1.767	1.00
74_D	540_R	1.753	1.00
79_Q	83_K	1.743	1.00
92_I	95_L	1.737	1.00
199_P	354_S	1.719	1.00
73_G	77_A	1.716	1.00
169_R	369_P	1.713	1.00
66_F	83_K	1.712	1.00
196_T	216_A	1.706	1.00
170_T	370_G	1.700	1.00
178_N	185_E	1.693	1.00
476_D	516_R	1.683	1.00
54_N	59_G	1.678	1.00
454_E	485_R	1.676	1.00
202_I	518_I	1.672	1.00
42_S	136_L	1.669	1.00
220_V	358_L	1.654	1.00
222_Q	510_N	1.641	1.00
227_Y	230_G	1.626	1.00
322_D	329_I	1.626	1.00
81_P	362_Y	1.625	1.00
458_W	478_K	1.608	1.00
363_D	405_N	1.607	1.00
476_D	520_L	1.590	1.00
23_A	146_Y	1.586	1.00
455_L	479_I	1.574	1.00
6_I	22_A	1.572	1.00
171_C	192_V	1.565	1.00
39_R	44_C	1.562	1.00
52_A	62_P	1.557	1.00
364_Q	402_A	1.557	1.00
402_A	406_A	1.545	1.00
226_Y	359_W	1.533	1.00
318_P	341_R	1.524	1.00
360_V	378_D	1.524	1.00
469_N	534_K	1.508	1.00
322_D	341_R	1.506	1.00
164_V	186_S	1.499	1.00
446_E	485_R	1.489	1.00
81_P	85_M	1.483	1.00
483_M	513_Q	1.482	1.00
66_F	70_V	1.480	1.00
313_L	316_K	1.477	1.00
4_S	7_I	1.461	1.00
94_H	98_R	1.461	1.00
21_K	404_P	1.461	1.00
220_V	225_A	1.458	1.00
34_I	507_Q	1.455	1.00
270_Y	273_E	1.454	1.00
462_N	475_T	1.441	1.00
475_T	519_T	1.435	1.00
478_K	481_E	1.422	1.00
62_P	87_E	1.421	1.00
49_I	135_L	1.419	1.00
34_I	215_S	1.414	1.00
462_N	471_K	1.411	1.00
62_P	66_F	1.401	1.00
42_S	395_A	1.399	1.00
469_N	523_Y	1.398	1.00
88_A	91_S	1.393	1.00
207_T	239_A	1.392	1.00
24_E	146_Y	1.391	1.00
4_S	153_T	1.387	1.00
250_S	253_A	1.384	1.00
4_S	28_A	1.384	1.00
143_V	154_K	1.383	1.00
92_I	400_M	1.382	1.00
194_M	371_L	1.377	1.00
170_T	369_P	1.374	1.00
158_W	178_N	1.373	1.00
476_D	523_Y	1.368	1.00
191_A	409_Y	1.367	1.00
189_S	192_V	1.366	1.00
97_D	111_L	1.365	1.00
34_I	213_T	1.352	1.00
355_M	531_A	1.346	1.00
516_R	520_L	1.344	1.00
228_A	359_W	1.343	1.00
215_S	510_N	1.340	1.00
203_F	463_V	1.338	1.00
199_P	233_I	1.336	1.00
200_G	351_V	1.326	1.00
457_E	461_A	1.326	1.00
16_L	143_V	1.321	1.00
250_S	328_I	1.321	1.00
405_N	409_Y	1.316	1.00
260_V	347_I	1.315	1.00
163_A	171_C	1.313	1.00
194_M	220_V	1.312	1.00
372_F	409_Y	1.309	1.00
81_P	381_M	1.295	1.00
329_I	341_R	1.291	1.00
4_S	155_Y	1.290	1.00
473_L	477_D	1.286	1.00
160_F	174_I	1.285	1.00
164_V	175_V	1.282	1.00
155_Y	158_W	1.278	1.00
259_R	281_N	1.277	1.00
101_V	135_L	1.272	1.00
50_N	389_A	1.271	1.00
290_R	533_Y	1.264	0.99
193_I	374_A	1.262	0.99
9_V	194_M	1.256	0.99
32_F	174_I	1.254	0.99
88_A	92_I	1.251	0.99
463_V	518_I	1.238	0.99
204_G	457_E	1.236	0.99
14_A	374_A	1.235	0.99
6_I	193_I	1.234	0.99
89_A	393_L	1.233	0.99
31_L	154_K	1.230	0.99
405_N	408_K	1.228	0.99
158_W	176_A	1.225	0.99
542_D	546_L	1.208	0.99
462_N	478_K	1.201	0.99
160_F	176_A	1.200	0.99
62_P	86_C	1.198	0.99
275_K	291_E	1.196	0.99
67_D	71_Y	1.190	0.99
522_A	532_H	1.181	0.99
50_N	119_T	1.170	0.99
63_W	67_D	1.170	0.99
11_G	33_S	1.165	0.99
256_E	324_K	1.164	0.99
65_H	390_N	1.162	0.99
66_F	86_C	1.156	0.99
217_A	514_L	1.152	0.99
17_M	21_K	1.151	0.99
400_M	404_P	1.151	0.99
21_K	403_G	1.149	0.99
162_G	219_I	1.148	0.99
143_V	152_V	1.146	0.99
469_N	537_Y	1.135	0.99
271_F	292_I	1.133	0.99
222_Q	513_Q	1.127	0.99
199_P	518_I	1.124	0.99
316_K	320_E	1.123	0.99
365_M	409_Y	1.121	0.99
158_W	185_E	1.118	0.99
21_K	400_M	1.116	0.99
63_W	83_K	1.107	0.99
144_R	156_E	1.099	0.99
318_P	342_K	1.097	0.99
231_E	525_R	1.094	0.99
360_V	373_A	1.089	0.98
7_I	32_F	1.085	0.98
321_L	329_I	1.080	0.98
16_L	31_L	1.080	0.98
84_A	362_Y	1.078	0.98
84_A	88_A	1.077	0.98
225_A	371_L	1.077	0.98
473_L	476_D	1.076	0.98
65_H	69_T	1.070	0.98
95_L	400_M	1.070	0.98
18_A	402_A	1.066	0.98
452_H	456_G	1.065	0.98
20_I	143_V	1.063	0.98
53_V	125_A	1.061	0.98
399_G	403_G	1.058	0.98
358_L	373_A	1.057	0.98
6_I	406_A	1.055	0.98
330_E	334_K	1.052	0.98
119_T	389_A	1.052	0.98
124_T	389_A	1.051	0.98
84_A	398_G	1.050	0.98
521_G	549_T	1.046	0.98
453_K	457_E	1.044	0.98
159_E	506_R	1.043	0.98
452_H	511_M	1.038	0.98
133_Q	137_Y	1.034	0.98
90_P	94_H	1.030	0.98
101_V	134_Q	1.028	0.98
458_W	462_N	1.026	0.98
18_A	406_A	1.025	0.98
217_A	354_S	1.024	0.98
275_K	295_V	1.022	0.98
101_V	138_A	1.019	0.98
31_L	143_V	1.012	0.98
66_F	79_Q	1.010	0.98
99_M	142_Q	1.009	0.97
111_L	125_A	1.009	0.97
486_F	512_L	1.006	0.97
458_W	482_L	1.005	0.97
403_G	407_V	1.001	0.97
191_A	372_F	1.001	0.97
542_D	545_W	1.000	0.97
455_L	508_F	0.995	0.97
76_L	529_R	0.994	0.97
64_E	120_Q	0.994	0.97
82_V	86_C	0.992	0.97
130_T	327_G	0.989	0.97
115_R	122_H	0.986	0.97
322_D	333_E	0.985	0.97
37_V	140_D	0.985	0.97
20_I	99_M	0.984	0.97
9_V	160_F	0.984	0.97
272_L	280_G	0.984	0.97
338_D	343_L	0.982	0.97
339_D	342_K	0.982	0.97
142_Q	146_Y	0.982	0.97
5_S	28_A	0.981	0.97
175_V	184_I	0.978	0.97
381_M	398_G	0.968	0.97
104_N	126_Y	0.968	0.97
264_K	306_E	0.960	0.97
270_Y	280_G	0.960	0.97
225_A	368_I	0.953	0.96
474_K	478_K	0.952	0.96
480_Q	520_L	0.948	0.96
21_K	24_E	0.948	0.96
7_I	189_S	0.947	0.96
317_D	320_E	0.942	0.96
141_E	145_R	0.937	0.96
20_I	146_Y	0.937	0.96
526_N	545_W	0.936	0.96
163_A	174_I	0.935	0.96
261_W	312_D	0.933	0.96
225_A	367_N	0.933	0.96
273_E	281_N	0.931	0.96
406_A	410_V	0.930	0.96
163_A	192_V	0.928	0.96
159_E	507_Q	0.928	0.96
467_R	522_A	0.925	0.96
165_L	171_C	0.922	0.96
175_V	186_S	0.921	0.96
310_Y	344_P	0.920	0.96
258_G	313_L	0.919	0.96
91_S	94_H	0.914	0.96
69_T	390_N	0.911	0.95
191_A	410_V	0.907	0.95
119_T	124_T	0.906	0.95
478_K	482_L	0.906	0.95
360_V	379_Y	0.904	0.95
271_F	281_N	0.904	0.95
140_D	154_K	0.904	0.95
374_A	402_A	0.902	0.95
43_V	133_Q	0.900	0.95
17_M	92_I	0.898	0.95
122_H	256_E	0.897	0.95
338_D	345_M	0.895	0.95
105_R	111_L	0.895	0.95
70_V	82_V	0.894	0.95
21_K	95_L	0.884	0.95
214_G	514_L	0.880	0.94
301_L	305_G	0.879	0.94
80_P	362_Y	0.878	0.94
259_R	315_H	0.878	0.94
102_M	134_Q	0.878	0.94
331_I	334_K	0.878	0.94
403_G	406_A	0.876	0.94
263_Y	266_G	0.875	0.94
319_K	323_I	0.874	0.94
283_V	288_A	0.868	0.94
332_Y	340_P	0.866	0.94
360_V	398_G	0.865	0.94
218_S	222_Q	0.861	0.94
6_I	27_M	0.859	0.94
230_G	518_I	0.854	0.94
455_L	512_L	0.853	0.94
85_M	393_L	0.853	0.94
283_V	287_I	0.852	0.93
51_G	93_I	0.850	0.93
6_I	26_G	0.847	0.93
190_D	410_V	0.846	0.93
233_I	518_I	0.846	0.93
472_L	519_T	0.845	0.93
35_V	211_I	0.845	0.93
81_P	84_A	0.845	0.93
45_A	48_G	0.844	0.93
114_R	256_E	0.844	0.93
218_S	514_L	0.843	0.93
169_R	368_I	0.843	0.93
452_H	508_F	0.842	0.93
253_A	313_L	0.841	0.93
96_L	135_L	0.841	0.93
275_K	294_D	0.840	0.93
204_G	460_T	0.840	0.93
261_W	310_Y	0.838	0.93
466_V	535_P	0.836	0.93
301_L	306_E	0.835	0.93
19_T	152_V	0.835	0.93
95_L	99_M	0.834	0.93
67_D	79_Q	0.832	0.93
66_F	82_V	0.832	0.93
321_L	341_R	0.832	0.93
118_G	355_M	0.831	0.93
136_L	140_D	0.828	0.92
70_V	77_A	0.828	0.92
251_E	254_R	0.827	0.92
49_I	93_I	0.825	0.92
332_Y	338_D	0.824	0.92
435_K	509_S	0.823	0.92
529_R	538_P	0.819	0.92
455_L	482_L	0.818	0.92
219_I	222_Q	0.814	0.92
226_Y	552_K	0.813	0.92
88_A	400_M	0.812	0.92
230_G	521_G	0.810	0.92
363_D	401_V	0.805	0.91
3_Q	28_A	0.800	0.91
195_A	374_A	0.799	0.91
479_I	516_R	0.798	0.91
459_M	515_A	0.797	0.91
230_G	514_L	0.797	0.91
213_T	507_Q	0.797	0.91
8_V	29_V	0.796	0.91
201_I	456_G	0.796	0.91
527_E	538_P	0.795	0.91
483_M	512_L	0.792	0.91
274_E	295_V	0.789	0.91
7_I	192_V	0.788	0.91
476_D	480_Q	0.788	0.91
62_P	90_P	0.788	0.91
226_Y	550_M	0.788	0.91
22_A	27_M	0.783	0.90
190_D	414_E	0.782	0.90
407_V	410_V	0.778	0.90
102_M	138_A	0.778	0.90
7_I	30_K	0.772	0.90
227_Y	517_V	0.771	0.90
49_I	396_I	0.770	0.90
52_A	86_C	0.767	0.89
329_I	340_P	0.767	0.89
301_L	304_N	0.765	0.89
18_A	22_A	0.762	0.89
95_L	98_R	0.758	0.89
466_V	533_Y	0.756	0.89
248_L	251_E	0.754	0.89
529_R	537_Y	0.753	0.88
86_C	89_A	0.752	0.88
332_Y	345_M	0.751	0.88
451_L	508_F	0.750	0.88
127_A	134_Q	0.747	0.88
229_N	548_T	0.746	0.88
193_I	402_A	0.746	0.88
520_L	524_N	0.746	0.88
264_K	307_N	0.744	0.88
448_A	505_T	0.741	0.88
320_E	323_I	0.739	0.88
102_M	105_R	0.739	0.88
404_P	408_K	0.738	0.87
218_S	510_N	0.738	0.87
165_L	169_R	0.735	0.87
319_K	322_D	0.733	0.87
294_D	466_V	0.732	0.87
22_A	26_G	0.732	0.87
178_N	183_Q	0.731	0.87
26_G	29_V	0.730	0.87
20_I	142_Q	0.728	0.87
450_V	454_E	0.728	0.87
23_A	152_V	0.726	0.87
7_I	187_F	0.725	0.87
207_T	350_A	0.725	0.87
470_D	474_K	0.725	0.87
193_I	410_V	0.724	0.86
409_Y	413_L	0.723	0.86
521_G	551_A	0.722	0.86
17_M	95_L	0.719	0.86
321_L	340_P	0.719	0.86
353_Y	356_G	0.718	0.86
23_A	29_V	0.717	0.86
116_F	124_T	0.717	0.86
70_V	79_Q	0.717	0.86
517_V	551_A	0.714	0.86
352_H	355_M	0.713	0.86
253_A	321_L	0.713	0.86
40_S	45_A	0.711	0.85
199_P	217_A	0.711	0.85
313_L	321_L	0.709	0.85
25_S	407_V	0.709	0.85
545_W	548_T	0.709	0.85
25_S	408_K	0.708	0.85
301_L	308_M	0.707	0.85
264_K	308_M	0.707	0.85
293_F	466_V	0.706	0.85
191_A	406_A	0.706	0.85
51_G	125_A	0.706	0.85
97_D	105_R	0.705	0.85
203_F	518_I	0.705	0.85
97_D	125_A	0.705	0.85
271_F	275_K	0.705	0.85
41_H	209_S	0.704	0.85
117_G	279_Y	0.703	0.85
473_L	520_L	0.703	0.85
114_R	126_Y	0.701	0.85
172_R	188_R	0.700	0.85
91_S	400_M	0.699	0.84
49_I	393_L	0.698	0.84
261_W	264_K	0.696	0.84
140_D	144_R	0.694	0.84
216_A	377_C	0.691	0.84
365_M	369_P	0.691	0.84
158_W	187_F	0.691	0.84
201_I	511_M	0.690	0.84
474_K	477_D	0.689	0.84
462_N	519_T	0.687	0.83
232_F	525_R	0.687	0.83
30_K	153_T	0.687	0.83
205_K	460_T	0.686	0.83
454_E	457_E	0.686	0.83
263_Y	274_E	0.685	0.83
408_K	412_G	0.684	0.83
166_D	169_R	0.681	0.83
236_H	251_E	0.680	0.83
35_V	39_R	0.680	0.83
202_I	514_L	0.680	0.83
233_I	354_S	0.679	0.83
190_D	415_S	0.677	0.83
27_M	407_V	0.677	0.83
8_V	18_A	0.677	0.83
43_V	137_Y	0.677	0.83
442_M	445_T	0.675	0.82
482_L	512_L	0.675	0.82
37_V	154_K	0.673	0.82
61_S	64_E	0.673	0.82
92_I	396_I	0.672	0.82
41_H	212_N	0.672	0.82
36_P	156_E	0.671	0.82
32_F	187_F	0.670	0.82
174_I	189_S	0.670	0.82
157_G	180_T	0.669	0.82
165_L	172_R	0.667	0.82
50_N	86_C	0.666	0.82
271_F	295_V	0.666	0.82
528_S	533_Y	0.665	0.81
372_F	406_A	0.663	0.81
249_M	345_M	0.662	0.81
333_E	341_R	0.661	0.81
374_A	403_G	0.660	0.81
171_C	368_I	0.659	0.81
32_F	155_Y	0.659	0.81
124_T	388_G	0.659	0.81
166_D	170_T	0.658	0.81
161_L	177_Q	0.657	0.81
467_R	532_H	0.656	0.81
13_L	139_L	0.655	0.80
5_S	27_M	0.655	0.80
116_F	389_A	0.655	0.80
260_V	272_L	0.655	0.80
200_G	206_S	0.655	0.80
526_N	544_E	0.655	0.80
137_Y	141_E	0.655	0.80
291_E	295_V	0.654	0.80
249_M	328_I	0.653	0.80
360_V	364_Q	0.653	0.80
309_V	347_I	0.653	0.80
513_Q	516_R	0.653	0.80
176_A	185_E	0.652	0.80
286_D	290_R	0.651	0.80
112_D	126_Y	0.651	0.80
221_Y	227_Y	0.650	0.80
200_G	208_N	0.649	0.80
374_A	399_G	0.648	0.80
451_L	454_E	0.647	0.80
102_M	137_Y	0.646	0.80
352_H	356_G	0.646	0.80
279_Y	287_I	0.645	0.79
264_K	304_N	0.645	0.79
23_A	407_V	0.645	0.79
446_E	454_E	0.645	0.79
446_E	450_V	0.644	0.79
58_E	110_L	0.643	0.79
295_V	301_L	0.643	0.79
276_Y	284_P	0.642	0.79
37_V	156_E	0.642	0.79
44_C	209_S	0.641	0.79
274_E	303_I	0.640	0.79
247_R	328_I	0.640	0.79
218_S	513_Q	0.639	0.79
221_Y	513_Q	0.638	0.79
267_K	295_V	0.636	0.78
202_I	515_A	0.636	0.78
196_T	377_C	0.635	0.78
164_V	188_R	0.634	0.78
247_R	331_I	0.634	0.78
64_E	67_D	0.634	0.78
291_E	294_D	0.634	0.78
165_L	168_D	0.633	0.78
199_P	202_I	0.632	0.78
170_T	409_Y	0.632	0.78
238_T	254_R	0.630	0.78
13_L	396_I	0.630	0.78
213_T	510_N	0.630	0.78
453_K	456_G	0.629	0.78
480_Q	484_E	0.629	0.78
25_S	404_P	0.629	0.78
41_H	44_C	0.628	0.78
52_A	65_H	0.628	0.78
365_M	372_F	0.627	0.77
389_A	394_S	0.626	0.77
376_E	386_R	0.626	0.77
481_E	485_R	0.625	0.77
306_E	309_V	0.624	0.77
236_H	254_R	0.623	0.77
458_W	479_I	0.622	0.77
23_A	147_E	0.621	0.77
27_M	410_V	0.621	0.77
471_K	475_T	0.618	0.76
477_D	480_Q	0.618	0.76
241_P	244_D	0.618	0.76
461_A	471_K	0.617	0.76
20_I	152_V	0.616	0.76
101_V	396_I	0.615	0.76
200_G	354_S	0.614	0.76
475_T	478_K	0.613	0.76
370_G	409_Y	0.611	0.76
50_N	124_T	0.609	0.75
161_L	184_I	0.608	0.75
484_E	487_K	0.608	0.75
179_L	503_M	0.607	0.75
62_P	83_K	0.606	0.75
11_G	31_L	0.606	0.75
481_E	484_E	0.605	0.75
284_P	287_I	0.604	0.75
228_A	379_Y	0.604	0.75
23_A	26_G	0.604	0.75
52_A	66_F	0.603	0.75
134_Q	138_A	0.603	0.75
251_E	255_G	0.602	0.75
191_A	370_G	0.602	0.75
200_G	233_I	0.601	0.74
293_F	302_G	0.600	0.74
162_G	223_Q	0.600	0.74
76_L	232_F	0.599	0.74
171_C	370_G	0.596	0.74
286_D	289_T	0.594	0.74
113_F	125_A	0.594	0.74
161_L	175_V	0.592	0.73
248_L	254_R	0.591	0.73
293_F	348_F	0.590	0.73
116_F	388_G	0.590	0.73
172_R	192_V	0.590	0.73
253_A	328_I	0.589	0.73
76_L	231_E	0.588	0.73
163_A	230_G	0.586	0.73
449_Y	504_F	0.586	0.73
17_M	399_G	0.585	0.73
317_D	341_R	0.585	0.73
263_Y	271_F	0.585	0.73
70_V	75_F	0.584	0.72
352_H	387_L	0.583	0.72
272_L	283_V	0.583	0.72
304_N	307_N	0.581	0.72
276_Y	283_V	0.581	0.72
545_W	549_T	0.581	0.72
216_A	223_Q	0.580	0.72
247_R	340_P	0.580	0.72
238_T	286_D	0.580	0.72
18_A	399_G	0.580	0.72
50_N	65_H	0.580	0.72
454_E	481_E	0.580	0.72
164_V	172_R	0.579	0.72
138_A	142_Q	0.577	0.71
398_G	401_V	0.576	0.71
486_F	489_I	0.576	0.71
452_H	507_Q	0.575	0.71
351_V	356_G	0.574	0.71
106_T	112_D	0.574	0.71
190_D	416_S	0.574	0.71
484_E	488_K	0.573	0.71
339_D	343_L	0.573	0.71
174_I	192_V	0.571	0.71
24_E	95_L	0.571	0.71
42_S	45_A	0.571	0.71
205_K	348_F	0.570	0.71
8_V	19_T	0.570	0.71
106_T	109_G	0.570	0.71
439_I	442_M	0.569	0.70
48_G	52_A	0.569	0.70
528_S	538_P	0.569	0.70
406_A	409_Y	0.568	0.70
479_I	512_L	0.567	0.70
264_K	310_Y	0.566	0.70
83_K	86_C	0.566	0.70
244_D	336_M	0.565	0.70
305_G	308_M	0.565	0.70
225_A	366_T	0.564	0.70
285_R	289_T	0.563	0.70
4_S	187_F	0.563	0.70
165_L	369_P	0.563	0.70
69_T	82_V	0.563	0.70
247_R	250_S	0.562	0.70
192_V	219_I	0.562	0.70
374_A	395_A	0.560	0.69
472_L	522_A	0.560	0.69
524_N	549_T	0.559	0.69
408_K	413_L	0.559	0.69
163_A	194_M	0.559	0.69
114_R	324_K	0.559	0.69
17_M	99_M	0.558	0.69
36_P	157_G	0.557	0.69
159_E	510_N	0.556	0.69
397_Y	401_V	0.556	0.69
441_S	481_E	0.556	0.69
461_A	474_K	0.556	0.69
94_H	97_D	0.555	0.69
166_D	172_R	0.555	0.69
8_V	193_I	0.555	0.69
238_T	251_E	0.554	0.68
21_K	25_S	0.554	0.68
81_P	379_Y	0.553	0.68
417_A	420_M	0.551	0.68
86_C	398_G	0.550	0.68
287_I	290_R	0.550	0.68
8_V	26_G	0.549	0.68
293_F	465_V	0.549	0.68
254_R	257_G	0.549	0.68
362_Y	398_G	0.548	0.68
39_R	42_S	0.547	0.67
259_R	280_G	0.547	0.67
544_E	547_K	0.546	0.67
470_D	473_L	0.546	0.67
116_F	119_T	0.546	0.67
459_M	462_N	0.544	0.67
378_D	398_G	0.543	0.67
446_E	451_L	0.541	0.67
279_Y	284_P	0.541	0.67
146_Y	152_V	0.540	0.66
135_L	396_I	0.540	0.66
40_S	136_L	0.539	0.66
452_H	504_F	0.539	0.66
527_E	537_Y	0.538	0.66
249_M	347_I	0.537	0.66
5_S	30_K	0.536	0.66
520_L	523_Y	0.534	0.66
451_L	512_L	0.533	0.65
349_P	352_H	0.532	0.65
507_Q	511_M	0.532	0.65
167_D	172_R	0.531	0.65
129_A	134_Q	0.531	0.65
271_F	291_E	0.530	0.65
165_L	368_I	0.530	0.65
59_G	121_H	0.529	0.65
331_I	336_M	0.528	0.65
49_I	103_F	0.528	0.65
88_A	397_Y	0.528	0.65
448_A	508_F	0.527	0.65
177_Q	506_R	0.527	0.65
292_I	347_I	0.527	0.65
130_T	134_Q	0.527	0.65
8_V	406_A	0.527	0.65
171_C	371_L	0.526	0.64
313_L	340_P	0.525	0.64
363_D	404_P	0.524	0.64
162_G	510_N	0.524	0.64
177_Q	182_M	0.524	0.64
21_K	399_G	0.524	0.64
519_T	523_Y	0.523	0.64
24_E	98_R	0.523	0.64
67_D	70_V	0.522	0.64
276_Y	287_I	0.522	0.64
192_V	370_G	0.519	0.63
350_A	353_Y	0.518	0.63
170_T	416_S	0.518	0.63
280_G	283_V	0.518	0.63
91_S	343_L	0.517	0.63
215_S	507_Q	0.517	0.63
455_L	511_M	0.517	0.63
303_I	308_M	0.516	0.63
303_I	310_Y	0.515	0.63
48_G	236_H	0.514	0.63
46_Q	325_L	0.514	0.63
263_Y	270_Y	0.513	0.63
33_S	154_K	0.513	0.63
347_I	356_G	0.512	0.62
451_L	489_I	0.512	0.62
126_Y	129_A	0.512	0.62
202_I	511_M	0.511	0.62
125_A	396_I	0.511	0.62
207_T	351_V	0.510	0.62
113_F	389_A	0.510	0.62
471_K	474_K	0.509	0.62
460_T	465_V	0.509	0.62
48_G	53_V	0.508	0.62
516_R	519_T	0.508	0.62
349_P	356_G	0.508	0.62
191_A	413_L	0.507	0.62
252_S	255_G	0.507	0.62
480_Q	483_M	0.506	0.61
22_A	407_V	0.506	0.61
105_R	109_G	0.506	0.61
37_V	40_S	0.506	0.61
49_I	52_A	0.505	0.61
231_E	521_G	0.505	0.61
66_F	87_E	0.505	0.61
108_E	147_E	0.505	0.61
47_G	254_R	0.504	0.61
266_G	344_P	0.502	0.61
82_V	85_M	0.502	0.61
409_Y	412_G	0.501	0.61
503_M	507_Q	0.501	0.61
33_S	156_E	0.501	0.61
434_E	437_A	0.500	0.61

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2bs2A	2	0.9744	100	0.271	Contact Map
2h88A	2	0.959	100	0.275	Contact Map
1kf6A	1	0.9488	100	0.279	Contact Map
2wdqA	1	0.9539	100	0.295	Contact Map
1chuA	2	0.7901	100	0.38	Contact Map
3gyxA	2	0.9027	100	0.387	Contact Map
2e5vA	1	0.8038	100	0.409	Contact Map
1jnrA	2	0.9113	100	0.417	Contact Map
4c3xA	4	0.6485	100	0.613	Contact Map
1y0pA	1	0.6433	100	0.656	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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