DNAB - BACSU - GREMLIN Contacts

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DNAB - Replication initiation and membrane attachment protein

UniProt:	P07908	Sequences: MADYWKDVLPVDPYVVKSRSMLQDIDRQIITQLYQPLIGPVAFSLYMTLWGELEQNRLWGGESTHRQLMGMTQSNLKTIHQEQGKLEGIGLLKVYMKESERQERLFIYELLPPLRPNEFFEDGMLNVFLYNRVGKTKYQQLKQFFTHPAISEDAKDITRPFNHAFESLQPSEWKLTSDMEETVRLAEGSEYTSVGQSPSYTITEDVFDFDLFLAGLSETMIPRKAMTQQVRDTIKKLSYLYGIDPLQMQNVVMSAIDERDVITTEALRKAASDWYQIERNGQLPDLVEKTQPVHLREGEQPAEEDSLDGKLIALLEAISPKKLLQDIADGTEPSKADLKIIEEIMFEQKLEPGVTNVLIYYVMLKTDMKLSKNYIQKIASHWARKKVKTVREAMKLAIEENRQYLEWAEGKTKSSKRNQKVIREEKLPDWMTEKETASDSESGQQKLHPQDLEEQKKKMMEEMQKLKKYSAY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	472 (428)
Sequences:	491 (432)
Seq/√Len:	20.9

BACSU - DNAB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
38_I	89_I	6.398	1.00
93_K	156_D	6.239	1.00
65_H	108_Y	5.518	1.00
353_G	390_V	4.632	1.00
244_D	247_Q	4.281	1.00
234_I	248_M	4.171	1.00
243_I	248_M	4.004	1.00
212_F	252_V	3.995	1.00
207_F	248_M	3.911	1.00
454_E	457_K	3.835	1.00
84_G	159_R	3.468	1.00
65_H	83_Q	3.252	1.00
340_I	375_I	3.204	1.00
35_Q	48_T	3.079	0.99
14_Y	52_E	2.893	0.99
387_V	396_L	2.883	0.99
381_H	400_E	2.720	0.99
262_I	267_L	2.581	0.98
388_K	392_E	2.561	0.98
457_K	460_M	2.510	0.98
316_E	353_G	2.501	0.98
73_Q	132_R	2.477	0.98
455_Q	458_K	2.332	0.96
215_G	249_Q	2.325	0.96
315_L	360_Y	2.290	0.96
451_D	455_Q	2.281	0.96
404_Y	407_W	2.257	0.96
237_L	267_L	2.228	0.95
158_T	164_A	2.192	0.95
268_R	342_E	2.192	0.95
93_K	111_L	2.161	0.94
133_V	141_L	2.136	0.94
457_K	461_E	2.104	0.94
230_V	262_I	2.064	0.93
209_F	231_R	2.033	0.92
126_N	130_Y	2.008	0.92
97_K	154_A	1.999	0.92
343_E	372_K	1.994	0.92
122_D	126_N	1.956	0.91
451_D	454_E	1.937	0.90
350_L	379_A	1.914	0.90
425_E	430_W	1.907	0.90
69_M	79_I	1.882	0.89
327_I	363_M	1.870	0.89
367_D	385_K	1.848	0.88
69_M	76_L	1.843	0.88
267_L	361_Y	1.831	0.88
316_E	391_R	1.804	0.87
133_V	137_K	1.763	0.86
401_N	404_Y	1.744	0.85
227_T	230_V	1.736	0.85
397_A	400_E	1.733	0.85
22_L	110_L	1.729	0.84
315_L	357_V	1.721	0.84
385_K	396_L	1.715	0.84
207_F	245_P	1.714	0.84
88_G	165_F	1.712	0.84
251_V	271_A	1.697	0.83
33_L	46_Y	1.680	0.83
27_R	50_W	1.652	0.82
344_I	355_T	1.632	0.81
337_D	380_S	1.632	0.81
107_I	163_H	1.613	0.80
91_L	113_P	1.599	0.79
94_V	234_I	1.598	0.79
323_L	337_D	1.588	0.79
95_Y	386_K	1.578	0.78
120_F	142_K	1.568	0.78
276_Q	283_L	1.565	0.78
16_V	49_L	1.551	0.77
123_G	126_N	1.550	0.77
87_E	108_Y	1.542	0.77
33_L	120_F	1.538	0.77
88_G	166_E	1.535	0.76
453_E	456_K	1.521	0.76
381_H	396_L	1.520	0.76
369_K	381_H	1.510	0.75
345_M	355_T	1.510	0.75
95_Y	109_E	1.509	0.75
454_E	458_K	1.500	0.75
382_W	393_A	1.500	0.75
315_L	364_L	1.499	0.75
263_T	266_A	1.487	0.74
66_R	69_M	1.487	0.74
99_S	103_E	1.480	0.74
323_L	338_L	1.479	0.74
93_K	374_Y	1.476	0.74
335_K	339_K	1.474	0.73
44_S	79_I	1.460	0.73
331_T	380_S	1.459	0.73
387_V	458_K	1.454	0.72
240_L	425_E	1.448	0.72
8_V	377_K	1.443	0.72
323_L	360_Y	1.443	0.72
369_K	400_E	1.439	0.72
137_K	140_Q	1.432	0.71
93_K	109_E	1.426	0.71
394_M	398_I	1.425	0.71
373_N	376_Q	1.418	0.70
18_S	53_L	1.418	0.70
35_Q	161_F	1.417	0.70
94_V	158_T	1.413	0.70
216_L	226_M	1.405	0.70
134_G	361_Y	1.391	0.69
328_A	337_D	1.387	0.69
64_T	92_L	1.386	0.69
450_Q	454_E	1.384	0.69
85_K	359_I	1.384	0.69
41_V	78_T	1.379	0.68
83_Q	92_L	1.372	0.68
332_E	380_S	1.363	0.67
133_V	383_A	1.354	0.67
95_Y	156_D	1.354	0.67
48_T	68_L	1.353	0.67
78_T	138_Y	1.351	0.67
333_P	374_Y	1.351	0.67
313_A	317_A	1.346	0.66
260_D	267_L	1.341	0.66
238_S	245_P	1.338	0.66
83_Q	108_Y	1.317	0.65
433_E	437_A	1.314	0.64
70_G	252_V	1.308	0.64
452_L	455_Q	1.308	0.64
80_H	83_Q	1.306	0.64
213_L	226_M	1.298	0.63
449_P	452_L	1.292	0.63
10_P	312_I	1.292	0.63
97_K	316_E	1.279	0.62
247_Q	351_E	1.278	0.62
106_F	128_F	1.262	0.61
207_F	234_I	1.262	0.61
425_E	432_T	1.255	0.61
314_L	318_I	1.253	0.61
68_L	79_I	1.252	0.61
351_E	373_N	1.249	0.60
311_L	360_Y	1.224	0.59
35_Q	145_F	1.224	0.59
348_Q	360_Y	1.223	0.59
72_T	79_I	1.223	0.59
44_S	198_P	1.220	0.59
416_K	419_Q	1.213	0.58
328_A	384_R	1.208	0.58
321_K	325_Q	1.202	0.57
82_E	159_R	1.198	0.57
107_I	154_A	1.194	0.57
207_F	249_Q	1.190	0.57
449_P	459_M	1.187	0.56
288_E	321_K	1.183	0.56
75_N	78_T	1.176	0.56
76_L	345_M	1.170	0.55
268_R	275_Y	1.167	0.55
321_K	338_L	1.160	0.55
396_L	400_E	1.159	0.55
14_Y	243_I	1.159	0.55
304_E	309_G	1.142	0.53
96_M	104_R	1.141	0.53
370_L	375_I	1.137	0.53
354_V	393_A	1.136	0.53
263_T	359_I	1.135	0.53
26_D	29_I	1.134	0.53
39_G	46_Y	1.134	0.53
10_P	69_M	1.133	0.53
355_T	375_I	1.132	0.53
207_F	212_F	1.130	0.53
85_K	161_F	1.127	0.52
414_S	419_Q	1.123	0.52
458_K	461_E	1.117	0.52
456_K	460_M	1.111	0.51
380_S	384_R	1.101	0.51
214_A	336_A	1.098	0.50
266_A	270_A	1.094	0.50
48_T	72_T	1.094	0.50
247_Q	250_N	1.092	0.50
394_M	397_A	1.089	0.50
362_V	375_I	1.089	0.50
49_L	68_L	1.087	0.50
391_R	395_K	1.087	0.50
35_Q	377_K	1.082	0.49
133_V	242_G	1.082	0.49
37_L	128_F	1.082	0.49
44_S	342_E	1.078	0.49
418_N	422_I	1.075	0.49
436_T	439_D	1.074	0.49
156_D	355_T	1.074	0.49
75_N	339_K	1.072	0.49
352_P	390_V	1.070	0.49
163_H	389_T	1.066	0.48
90_G	324_L	1.064	0.48
30_I	110_L	1.062	0.48
405_L	414_S	1.055	0.48
355_T	381_H	1.052	0.47
38_I	406_E	1.050	0.47
374_Y	377_K	1.046	0.47
75_N	249_Q	1.045	0.47
108_Y	248_M	1.045	0.47
234_I	417_R	1.043	0.47
88_G	158_T	1.039	0.47
389_T	392_E	1.039	0.47
411_K	415_S	1.038	0.47
13_P	62_E	1.036	0.46
325_Q	332_E	1.033	0.46
212_F	387_V	1.032	0.46
12_D	106_F	1.032	0.46
95_Y	158_T	1.029	0.46
357_V	384_R	1.018	0.45
211_L	246_L	1.016	0.45
212_F	249_Q	1.011	0.45
55_Q	60_G	1.011	0.45
60_G	82_E	1.009	0.45
369_K	397_A	1.007	0.44
315_L	394_M	1.007	0.44
251_V	351_E	1.007	0.44
160_P	221_I	1.006	0.44
85_K	338_L	1.004	0.44
434_K	454_E	1.002	0.44
350_L	357_V	1.001	0.44
249_Q	253_M	0.995	0.44
343_E	376_Q	0.994	0.44
37_L	140_Q	0.993	0.44
158_T	392_E	0.991	0.43
402_R	415_S	0.990	0.43
208_D	234_I	0.987	0.43
208_D	382_W	0.978	0.43
331_T	384_R	0.975	0.42
231_R	235_K	0.974	0.42
365_K	401_N	0.967	0.42
155_K	373_N	0.965	0.42
386_K	407_W	0.959	0.41
90_G	141_L	0.957	0.41
241_Y	393_A	0.955	0.41
453_E	457_K	0.955	0.41
223_R	344_I	0.949	0.41
163_H	193_S	0.946	0.41
153_D	414_S	0.941	0.40
53_L	60_G	0.939	0.40
258_E	263_T	0.937	0.40
69_M	368_M	0.934	0.40
241_Y	366_T	0.929	0.39
16_V	424_E	0.929	0.39
88_G	240_L	0.926	0.39
414_S	441_E	0.924	0.39
401_N	407_W	0.922	0.39
90_G	161_F	0.921	0.39
66_R	380_S	0.920	0.39
65_H	382_W	0.916	0.39
208_D	393_A	0.911	0.38
37_L	342_E	0.911	0.38
212_F	365_K	0.909	0.38
372_K	375_I	0.908	0.38
387_V	405_L	0.907	0.38
248_M	286_L	0.905	0.38
259_R	435_E	0.904	0.38
350_L	354_V	0.903	0.38
28_Q	80_H	0.902	0.38
10_P	430_W	0.901	0.38
308_D	398_I	0.900	0.38
361_Y	366_T	0.899	0.38
382_W	430_W	0.899	0.38
87_E	94_V	0.897	0.37
128_F	167_S	0.896	0.37
233_T	248_M	0.895	0.37
320_P	393_A	0.894	0.37
69_M	249_Q	0.891	0.37
268_R	272_S	0.889	0.37
324_L	393_A	0.885	0.37
355_T	387_V	0.885	0.37
114_L	244_D	0.883	0.37
252_V	392_E	0.883	0.37
128_F	268_R	0.881	0.36
73_Q	278_E	0.877	0.36
357_V	394_M	0.869	0.36
202_I	205_D	0.868	0.36
374_Y	381_H	0.868	0.36
93_K	392_E	0.866	0.36
436_T	450_Q	0.865	0.35
368_M	381_H	0.864	0.35
8_V	12_D	0.857	0.35
164_A	344_I	0.856	0.35
116_P	120_F	0.851	0.35
429_D	432_T	0.851	0.35
45_L	79_I	0.849	0.35
22_L	45_L	0.845	0.34
275_Y	284_P	0.844	0.34
102_Q	441_E	0.843	0.34
419_Q	422_I	0.843	0.34
36_P	46_Y	0.839	0.34
362_V	374_Y	0.833	0.34
89_I	165_F	0.831	0.33
450_Q	453_E	0.828	0.33
133_V	136_T	0.826	0.33
268_R	331_T	0.820	0.33
126_N	138_Y	0.818	0.33
387_V	390_V	0.818	0.33
234_I	433_E	0.816	0.33
35_Q	39_G	0.815	0.33
367_D	372_K	0.814	0.32
32_Q	145_F	0.814	0.32
22_L	46_Y	0.812	0.32
303_E	309_G	0.810	0.32
358_L	378_I	0.810	0.32
433_E	450_Q	0.809	0.32
337_D	370_L	0.807	0.32
328_A	380_S	0.807	0.32
43_F	47_M	0.805	0.32
377_K	398_I	0.804	0.32
344_I	375_I	0.803	0.32
87_E	90_G	0.802	0.32
65_H	126_N	0.801	0.32
455_Q	460_M	0.800	0.32
361_Y	374_Y	0.800	0.32
157_I	377_K	0.800	0.32
241_Y	342_E	0.798	0.32
95_Y	374_Y	0.798	0.32
163_H	241_Y	0.798	0.32
22_L	50_W	0.792	0.31
266_A	365_K	0.791	0.31
209_F	248_M	0.787	0.31
49_L	361_Y	0.787	0.31
334_S	380_S	0.784	0.31
108_Y	361_Y	0.783	0.31
165_F	294_H	0.783	0.31
395_K	399_E	0.782	0.31
20_S	26_D	0.779	0.30
34_Y	114_L	0.779	0.30
148_P	303_E	0.778	0.30
219_T	375_I	0.777	0.30
428_P	431_M	0.776	0.30
46_Y	237_L	0.775	0.30
44_S	47_M	0.774	0.30
37_L	114_L	0.772	0.30
415_S	438_S	0.771	0.30
244_D	262_I	0.769	0.30
35_Q	132_R	0.768	0.30
371_S	431_M	0.768	0.30
50_W	92_L	0.766	0.30
85_K	165_F	0.766	0.30
160_P	210_D	0.766	0.30
426_K	438_S	0.766	0.30
368_M	385_K	0.765	0.30
72_T	110_L	0.765	0.30
163_H	374_Y	0.765	0.30
42_A	126_N	0.764	0.30
56_N	144_F	0.764	0.30
438_S	454_E	0.762	0.30
123_G	268_R	0.760	0.29
321_K	359_I	0.759	0.29
221_I	313_A	0.756	0.29
96_M	142_K	0.755	0.29
207_F	236_K	0.753	0.29
88_G	147_H	0.752	0.29
106_F	245_P	0.751	0.29
115_R	435_E	0.750	0.29
220_M	369_K	0.747	0.29
287_V	457_K	0.745	0.29
90_G	320_P	0.744	0.29
418_N	421_V	0.741	0.28
216_L	252_V	0.740	0.28
315_L	397_A	0.739	0.28
299_E	303_E	0.739	0.28
70_G	108_Y	0.738	0.28
47_M	214_A	0.737	0.28
92_L	157_I	0.737	0.28
311_L	327_I	0.735	0.28
233_T	264_T	0.730	0.28
40_P	44_S	0.730	0.28
105_L	156_D	0.729	0.28
122_D	242_G	0.728	0.28
93_K	213_L	0.727	0.28
126_N	268_R	0.724	0.27
414_S	417_R	0.723	0.27
337_D	381_H	0.722	0.27
36_P	42_A	0.721	0.27
131_N	431_M	0.721	0.27
35_Q	400_E	0.721	0.27
328_A	368_M	0.720	0.27
34_Y	129_L	0.720	0.27
82_E	92_L	0.719	0.27
381_H	384_R	0.718	0.27
99_S	102_Q	0.717	0.27
327_I	347_E	0.715	0.27
325_Q	333_P	0.714	0.27
157_I	265_E	0.714	0.27
22_L	167_S	0.710	0.27
358_L	382_W	0.709	0.27
40_P	387_V	0.708	0.27
287_V	452_L	0.704	0.26
146_T	273_D	0.704	0.26
136_T	143_Q	0.704	0.26
71_M	79_I	0.704	0.26
203_T	263_T	0.704	0.26
76_L	79_I	0.704	0.26
340_I	344_I	0.701	0.26
19_R	94_V	0.700	0.26
437_A	442_S	0.698	0.26
335_K	419_Q	0.697	0.26
37_L	92_L	0.694	0.26
150_I	263_T	0.694	0.26
415_S	457_K	0.693	0.26
118_E	173_W	0.691	0.26
337_D	364_L	0.690	0.26
241_Y	382_W	0.690	0.26
340_I	352_P	0.689	0.26
118_E	392_E	0.688	0.26
234_I	419_Q	0.688	0.26
31_T	95_Y	0.684	0.25
361_Y	400_E	0.683	0.25
416_K	441_E	0.683	0.25
279_R	351_E	0.678	0.25
311_L	323_L	0.678	0.25
371_S	380_S	0.676	0.25
370_L	403_Q	0.676	0.25
314_L	360_Y	0.675	0.25
158_T	227_T	0.674	0.25
207_F	238_S	0.673	0.25
238_S	337_D	0.672	0.25
87_E	158_T	0.670	0.25
250_N	372_K	0.670	0.25
218_E	398_I	0.669	0.25
7_D	269_K	0.668	0.25
240_L	319_S	0.668	0.25
107_I	192_T	0.667	0.25
387_V	403_Q	0.667	0.25
157_I	261_V	0.665	0.24
413_K	439_D	0.665	0.24
272_S	342_E	0.664	0.24
95_Y	213_L	0.660	0.24
415_S	418_N	0.660	0.24
74_S	155_K	0.658	0.24
22_L	141_L	0.656	0.24
154_A	248_M	0.656	0.24
337_D	384_R	0.656	0.24
87_E	241_Y	0.655	0.24
33_L	379_A	0.652	0.24
81_Q	303_E	0.652	0.24
62_E	131_N	0.649	0.24
157_I	420_K	0.649	0.24
443_G	459_M	0.645	0.23
256_I	397_A	0.644	0.23
311_L	328_A	0.642	0.23
331_T	394_M	0.641	0.23
46_Y	257_D	0.640	0.23
144_F	378_I	0.638	0.23
240_L	321_K	0.638	0.23
97_K	157_I	0.635	0.23
435_E	450_Q	0.635	0.23
152_E	417_R	0.634	0.23
300_Q	443_G	0.634	0.23
42_A	143_Q	0.634	0.23
156_D	261_V	0.632	0.23
66_R	70_G	0.632	0.23
406_E	461_E	0.631	0.23
219_T	260_D	0.630	0.23
150_I	204_E	0.628	0.23
304_E	308_D	0.627	0.23
237_L	262_I	0.626	0.23
330_G	382_W	0.626	0.23
94_V	307_L	0.625	0.23
441_E	457_K	0.624	0.23
29_I	378_I	0.624	0.23
98_E	155_K	0.623	0.22
116_P	387_V	0.620	0.22
89_I	122_D	0.619	0.22
47_M	244_D	0.618	0.22
154_A	435_E	0.618	0.22
350_L	355_T	0.617	0.22
30_I	313_A	0.616	0.22
368_M	372_K	0.616	0.22
123_G	138_Y	0.615	0.22
387_V	435_E	0.615	0.22
28_Q	54_E	0.614	0.22
330_G	346_F	0.614	0.22
151_S	359_I	0.613	0.22
30_I	269_K	0.613	0.22
242_G	332_E	0.612	0.22
329_D	397_A	0.611	0.22
65_H	130_Y	0.610	0.22
122_D	425_E	0.609	0.22
168_L	429_D	0.609	0.22
30_I	36_P	0.609	0.22
385_K	399_E	0.608	0.22
360_Y	397_A	0.606	0.22
84_G	341_I	0.605	0.22
415_S	424_E	0.605	0.22
196_Q	351_E	0.605	0.22
202_I	280_N	0.605	0.22
62_E	82_E	0.604	0.22
163_H	205_D	0.603	0.22
348_Q	379_A	0.603	0.22
323_L	327_I	0.603	0.22
196_Q	412_T	0.602	0.22
46_Y	85_K	0.602	0.22
60_G	141_L	0.602	0.22
52_E	145_F	0.601	0.21
315_L	328_A	0.601	0.21
397_A	423_R	0.599	0.21
325_Q	392_E	0.598	0.21
8_V	157_I	0.598	0.21
115_R	451_D	0.596	0.21
45_L	406_E	0.596	0.21
41_V	74_S	0.595	0.21
247_Q	361_Y	0.594	0.21
277_I	333_P	0.594	0.21
8_V	350_L	0.593	0.21
57_R	88_G	0.593	0.21
395_K	449_P	0.593	0.21
111_L	156_D	0.590	0.21
12_D	342_E	0.590	0.21
440_S	443_G	0.590	0.21
424_E	460_M	0.588	0.21
427_L	431_M	0.588	0.21
23_Q	142_K	0.586	0.21
7_D	21_M	0.586	0.21
128_F	159_R	0.586	0.21
155_K	180_E	0.585	0.21
315_L	337_D	0.585	0.21
317_A	414_S	0.584	0.21
122_D	226_M	0.582	0.21
35_Q	427_L	0.581	0.21
141_L	427_L	0.580	0.21
62_E	99_S	0.579	0.20
363_M	396_L	0.579	0.20
338_L	384_R	0.578	0.20
140_Q	201_T	0.577	0.20
16_V	76_L	0.576	0.20
24_D	159_R	0.575	0.20
237_L	353_G	0.574	0.20
91_L	356_N	0.574	0.20
337_D	352_P	0.572	0.20
36_P	86_L	0.570	0.20
126_N	144_F	0.569	0.20
122_D	141_L	0.568	0.20
255_A	427_L	0.567	0.20
81_Q	116_P	0.567	0.20
381_H	404_Y	0.567	0.20
263_T	420_K	0.566	0.20
124_M	425_E	0.566	0.20
126_N	147_H	0.565	0.20
29_I	32_Q	0.565	0.20
87_E	125_L	0.564	0.20
9_L	66_R	0.563	0.20
314_L	327_I	0.562	0.20
51_G	212_F	0.562	0.20
255_A	299_E	0.561	0.20
242_G	321_K	0.560	0.20
82_E	260_D	0.560	0.20
181_E	261_V	0.559	0.20
325_Q	398_I	0.559	0.20
451_D	458_K	0.558	0.20
26_D	212_F	0.558	0.20
323_L	328_A	0.558	0.20
315_L	363_M	0.557	0.20
401_N	405_L	0.557	0.20
285_D	293_V	0.557	0.20
98_E	395_K	0.555	0.19
454_E	460_M	0.555	0.19
358_L	379_A	0.554	0.19
299_E	304_E	0.554	0.19
10_P	382_W	0.551	0.19
193_S	440_S	0.550	0.19
452_L	458_K	0.550	0.19
15_V	30_I	0.550	0.19
83_Q	87_E	0.549	0.19
39_G	85_K	0.549	0.19
108_Y	268_R	0.549	0.19
34_Y	134_G	0.549	0.19
334_S	337_D	0.548	0.19
261_V	406_E	0.548	0.19
115_R	181_E	0.547	0.19
315_L	374_Y	0.547	0.19
8_V	257_D	0.546	0.19
142_K	341_I	0.545	0.19
160_P	240_L	0.544	0.19
97_K	153_D	0.543	0.19
196_Q	435_E	0.543	0.19
90_G	393_A	0.543	0.19
357_V	400_E	0.542	0.19
344_I	371_S	0.542	0.19
355_T	384_R	0.541	0.19
85_K	334_S	0.541	0.19
424_E	449_P	0.540	0.19
303_E	413_K	0.540	0.19
292_P	313_A	0.540	0.19
124_M	131_N	0.540	0.19
242_G	249_Q	0.540	0.19
389_T	434_K	0.539	0.19
34_Y	46_Y	0.538	0.19
357_V	393_A	0.538	0.19
332_E	337_D	0.537	0.19
194_V	202_I	0.535	0.19
226_M	266_A	0.534	0.19
351_E	354_V	0.533	0.19
271_A	386_K	0.533	0.19
14_Y	384_R	0.532	0.19
33_L	36_P	0.532	0.19
125_L	275_Y	0.531	0.18
8_V	65_H	0.530	0.18
30_I	117_N	0.528	0.18
87_E	320_P	0.528	0.18
417_R	457_K	0.528	0.18
28_Q	282_Q	0.527	0.18
259_R	266_A	0.527	0.18
23_Q	145_F	0.525	0.18
14_Y	67_Q	0.524	0.18
135_K	139_Q	0.522	0.18
245_P	305_D	0.521	0.18
31_T	227_T	0.521	0.18
35_Q	423_R	0.520	0.18
90_G	241_Y	0.519	0.18
161_F	247_Q	0.516	0.18
324_L	370_L	0.516	0.18
52_E	366_T	0.516	0.18
449_P	453_E	0.515	0.18
80_H	84_G	0.515	0.18
131_N	167_S	0.514	0.18
155_K	285_D	0.513	0.18
360_Y	394_M	0.512	0.18
379_A	398_I	0.512	0.18
89_I	318_I	0.511	0.18
78_T	373_N	0.511	0.18
282_Q	306_S	0.509	0.18
127_V	219_T	0.508	0.18
227_T	384_R	0.508	0.18
13_P	103_E	0.507	0.18
195_G	199_S	0.507	0.18
221_I	425_E	0.507	0.18
37_L	163_H	0.507	0.18
231_R	248_M	0.506	0.18
196_Q	294_H	0.505	0.17
22_L	130_Y	0.505	0.17
97_K	388_K	0.505	0.17
248_M	267_L	0.504	0.17
65_H	209_F	0.504	0.17
438_S	441_E	0.503	0.17
13_P	102_Q	0.502	0.17
46_Y	78_T	0.502	0.17
272_S	283_L	0.502	0.17
74_S	171_S	0.502	0.17
64_T	158_T	0.502	0.17
106_F	353_G	0.501	0.17
337_D	348_Q	0.501	0.17
38_I	43_F	0.500	0.17
253_M	311_L	0.500	0.17

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2zc2A	1	0.1589	98.8	0.904	Contact Map
2i5uA	1	0.1483	97.8	0.929	Contact Map
2v79A	4	0.2436	70.9	0.965	Contact Map
4pt7A	3	0.2564	68.4	0.965	Contact Map
2vn2A	4	0.2309	57.1	0.968	Contact Map
4ptaD	3	0.2309	54.8	0.968	Contact Map
3by6A	2	0.25	47.2	0.969	Contact Map
4kmfA	1	0.1314	46.4	0.969	Contact Map
1r1tA	2	0.2076	44.3	0.97	Contact Map
4r1hA	2	0.2267	43.9	0.97	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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