SCRB - BACSU - GREMLIN Contacts

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SCRB - Sucrose-6-phosphate hydrolase

UniProt:	P07819	Sequences: MTAHDQELRRRAYEEVEKKEPIANSDPHRQHFHIMPPVGLLNDPNGVIYWKGSYHVFFQWQPFQTGHGAKFWGHYTTQDVVNWKREEIALAPSDWFDKNGCYSGSAVTKDDRLYLFYTGNVRDQDGNRETYQCLAVSDDGLSFEKKGVVARLPEGYTAHFRDPKVWEHEGTWYMVIGAQTENLKGQAVLFASDNLTEWRFLGPITGAGFNGLDDFGYMWECPDLFSLQGSDVLIVSPQGLEADGFRYQNVYQSGYFVGRLDYNKPELKHGEFTELDQGFDFYAPQTLEDDQGRRILFAWMAVPDQDEGSHPTIDCHWIHCMTLPRQLTLSGQKLIQQPLPELKAMRRNEKKIHINMHGSSGALPVEKPERTEILLEDIHTESGFSISIRGTATFSFHKDEGIVTLERKSFDGKRTEARHCRIKDLHTVHMFLDASSVEIFINNGEEVLSARYFPFPGNHEVTASATGKSEMNVGIWTLM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	479 (431)
Sequences:	3259 (2480)
Seq/√Len:	119.5

BACSU - SCRB LEVB SACC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
194_N	197_E	5.530	1.00
76_T	86_E	4.604	1.00
293_R	341_E	4.406	1.00
191_A	201_L	3.904	1.00
53_S	76_T	3.839	1.00
323_L	431_F	3.817	1.00
79_D	82_N	3.764	1.00
225_F	294_R	3.537	1.00
171_T	191_A	3.529	1.00
372_E	429_H	3.398	1.00
385_S	464_S	3.347	1.00
77_T	80_V	3.323	1.00
346_R	372_E	3.229	1.00
427_T	443_N	3.063	1.00
371_T	432_L	3.047	1.00
53_S	78_Q	3.025	1.00
293_R	326_Q	2.926	1.00
300_M	436_S	2.839	1.00
119_G	133_C	2.793	1.00
223_D	286_T	2.713	1.00
34_I	75_Y	2.687	1.00
340_P	343_K	2.624	1.00
36_P	41_L	2.608	1.00
55_H	74_H	2.498	1.00
167_E	170_G	2.487	1.00
191_A	199_R	2.480	1.00
257_V	329_L	2.473	1.00
32_F	431_F	2.365	1.00
30_Q	35_M	2.361	1.00
233_L	236_S	2.318	1.00
430_M	439_I	2.314	1.00
226_S	229_G	2.309	1.00
286_T	294_R	2.287	1.00
164_K	223_D	2.277	1.00
395_S	404_T	2.242	1.00
376_E	427_T	2.209	1.00
295_I	339_L	2.168	1.00
56_V	321_M	2.167	1.00
77_T	83_W	2.152	1.00
372_E	431_F	2.144	1.00
116_F	134_L	2.125	1.00
108_T	111_D	2.118	1.00
58_F	85_R	2.115	1.00
107_V	172_W	2.105	1.00
47_V	287_L	2.068	1.00
374_L	427_T	2.048	1.00
235_V	256_F	2.033	1.00
61_Q	69_A	2.004	1.00
397_H	400_E	2.003	1.00
254_G	272_F	1.983	1.00
116_F	174_M	1.952	1.00
374_L	429_H	1.939	1.00
34_I	56_V	1.914	1.00
114_Y	134_L	1.886	1.00
116_F	195_L	1.878	1.00
29_R	35_M	1.847	1.00
442_N	445_E	1.833	1.00
146_K	149_V	1.824	1.00
328_T	337_Q	1.815	1.00
300_M	449_S	1.809	1.00
76_T	84_K	1.808	1.00
284_P	296_L	1.787	1.00
40_L	67_H	1.770	1.00
67_H	70_K	1.768	1.00
291_Q	340_P	1.751	1.00
48_I	108_T	1.744	1.00
171_T	193_D	1.735	1.00
411_D	414_R	1.721	1.00
295_I	324_P	1.713	1.00
53_S	86_E	1.712	1.00
78_Q	84_K	1.707	1.00
323_L	342_L	1.703	1.00
30_Q	320_C	1.697	1.00
300_M	322_T	1.694	1.00
226_S	231_D	1.688	1.00
120_N	130_T	1.687	1.00
435_S	451_R	1.674	1.00
410_F	414_R	1.665	1.00
112_R	138_D	1.649	1.00
391_T	409_S	1.648	1.00
135_A	145_K	1.636	1.00
390_G	455_F	1.625	1.00
109_K	172_W	1.623	1.00
326_Q	340_P	1.621	1.00
45_N	103_S	1.613	1.00
333_K	445_E	1.606	1.00
47_V	56_V	1.588	1.00
346_R	429_H	1.588	1.00
112_R	136_V	1.569	1.00
49_Y	290_D	1.542	1.00
37_P	85_R	1.541	1.00
261_D	264_K	1.536	1.00
165_V	174_M	1.531	1.00
137_S	143_F	1.526	1.00
432_L	437_V	1.525	1.00
338_P	440_F	1.511	1.00
387_S	391_T	1.509	1.00
337_Q	443_N	1.497	1.00
93_S	145_K	1.486	1.00
160_F	176_I	1.481	1.00
328_T	335_I	1.476	1.00
232_V	257_V	1.474	1.00
137_S	140_G	1.469	1.00
411_D	415_T	1.464	1.00
286_T	296_L	1.457	1.00
392_A	437_V	1.456	1.00
186_Q	203_P	1.453	1.00
223_D	294_R	1.413	1.00
326_Q	337_Q	1.412	1.00
405_L	450_A	1.402	1.00
410_F	415_T	1.378	1.00
376_E	425_L	1.377	1.00
178_A	188_V	1.354	1.00
232_V	329_L	1.339	1.00
403_V	441_I	1.333	1.00
406_E	409_S	1.331	1.00
230_S	257_V	1.321	1.00
180_T	184_K	1.311	1.00
43_D	46_G	1.310	1.00
232_V	236_S	1.305	1.00
187_A	219_W	1.304	1.00
61_Q	64_Q	1.294	1.00
86_E	141_L	1.292	1.00
80_V	83_W	1.289	1.00
230_S	259_R	1.289	1.00
53_S	141_L	1.288	1.00
168_H	226_S	1.270	1.00
383_G	397_H	1.265	0.99
231_D	234_I	1.263	0.99
40_L	70_K	1.262	0.99
282_Y	299_W	1.259	0.99
387_S	393_T	1.256	0.99
343_K	429_H	1.252	0.99
390_G	458_N	1.245	0.99
192_S	198_W	1.242	0.99
109_K	167_E	1.238	0.99
43_D	221_C	1.225	0.99
225_F	286_T	1.213	0.99
281_F	298_A	1.213	0.99
48_I	113_L	1.208	0.99
148_V	151_R	1.207	0.99
51_K	139_D	1.206	0.99
193_D	199_R	1.201	0.99
273_T	333_K	1.194	0.99
108_T	113_L	1.193	0.99
168_H	262_Y	1.183	0.99
410_F	413_K	1.179	0.99
346_R	374_L	1.178	0.99
82_N	345_M	1.176	0.99
394_F	403_V	1.172	0.99
109_K	112_R	1.156	0.99
289_D	293_R	1.152	0.99
231_D	259_R	1.148	0.99
109_K	114_Y	1.146	0.99
31_H	370_R	1.145	0.99
180_T	186_Q	1.144	0.99
187_A	233_L	1.142	0.99
262_Y	265_P	1.135	0.99
231_D	236_S	1.134	0.99
90_L	101_C	1.130	0.99
227_L	294_R	1.126	0.99
277_Q	448_L	1.118	0.99
50_W	108_T	1.117	0.99
164_K	286_T	1.117	0.99
192_S	195_L	1.117	0.99
31_H	434_A	1.116	0.99
140_G	143_F	1.110	0.99
46_G	59_Q	1.100	0.99
277_Q	446_E	1.100	0.99
49_Y	54_Y	1.098	0.99
159_H	179_Q	1.094	0.99
200_F	203_P	1.092	0.98
412_G	415_T	1.083	0.98
43_D	299_W	1.082	0.98
188_V	200_F	1.080	0.98
93_S	97_D	1.076	0.98
436_S	440_F	1.075	0.98
176_I	190_F	1.075	0.98
71_F	92_P	1.073	0.98
330_S	335_I	1.061	0.98
57_F	89_A	1.060	0.98
58_F	73_G	1.057	0.98
116_F	165_V	1.052	0.98
40_L	60_W	1.050	0.98
402_I	419_H	1.050	0.98
394_F	405_L	1.047	0.98
253_S	284_P	1.038	0.98
320_C	449_S	1.031	0.98
300_M	320_C	1.031	0.98
387_S	462_T	1.029	0.98
41_L	321_M	1.029	0.98
146_K	150_A	1.022	0.98
260_L	265_P	1.018	0.98
411_D	416_E	1.015	0.98
405_L	448_L	1.014	0.98
137_S	141_L	1.010	0.97
465_A	470_E	1.010	0.97
173_Y	189_L	1.009	0.97
320_C	436_S	1.003	0.97
281_F	296_L	1.003	0.97
298_A	325_R	1.003	0.97
26_D	315_C	1.002	0.97
47_V	297_F	1.001	0.97
437_V	450_A	1.001	0.97
114_Y	172_W	0.997	0.97
346_R	431_F	0.997	0.97
136_V	146_K	0.996	0.97
106_A	115_L	0.987	0.97
383_G	466_T	0.986	0.97
73_G	85_R	0.984	0.97
161_R	220_E	0.974	0.97
27_P	315_C	0.972	0.97
117_Y	135_A	0.971	0.97
92_P	100_G	0.971	0.97
276_D	325_R	0.969	0.97
71_F	91_A	0.969	0.97
57_F	115_L	0.968	0.97
42_N	59_Q	0.963	0.97
370_R	434_A	0.963	0.97
34_I	85_R	0.953	0.96
147_G	150_A	0.952	0.96
179_Q	183_L	0.952	0.96
236_S	253_S	0.951	0.96
117_Y	145_K	0.951	0.96
156_Y	200_F	0.948	0.96
326_Q	341_E	0.940	0.96
389_R	452_Y	0.939	0.96
47_V	285_Q	0.934	0.96
392_A	452_Y	0.933	0.96
288_E	294_R	0.929	0.96
114_Y	195_L	0.928	0.96
43_D	47_V	0.927	0.96
302_V	305_Q	0.927	0.96
139_D	142_S	0.920	0.96
43_D	283_A	0.914	0.95
170_G	193_D	0.914	0.95
325_R	336_Q	0.913	0.95
295_I	341_E	0.912	0.95
70_K	102_Y	0.912	0.95
172_W	192_S	0.904	0.95
108_T	114_Y	0.902	0.95
164_K	285_Q	0.899	0.95
45_N	285_Q	0.899	0.95
89_A	143_F	0.898	0.95
369_E	434_A	0.896	0.95
43_D	282_Y	0.896	0.95
255_Y	329_L	0.894	0.95
343_K	346_R	0.891	0.95
216_G	219_W	0.891	0.95
157_T	179_Q	0.890	0.95
298_A	322_T	0.882	0.95
373_I	430_M	0.882	0.95
147_G	151_R	0.882	0.95
133_C	149_V	0.880	0.94
97_D	100_G	0.880	0.94
75_Y	85_R	0.880	0.94
403_V	428_V	0.879	0.94
166_W	189_L	0.878	0.94
406_E	410_F	0.876	0.94
327_L	336_Q	0.875	0.94
217_Y	239_G	0.873	0.94
24_N	31_H	0.872	0.94
224_L	231_D	0.872	0.94
50_W	113_L	0.871	0.94
74_H	83_W	0.869	0.94
326_Q	339_L	0.866	0.94
101_C	145_K	0.865	0.94
288_E	292_G	0.864	0.94
336_Q	447_V	0.864	0.94
436_S	449_S	0.861	0.94
342_L	431_F	0.861	0.94
96_F	133_C	0.850	0.93
43_D	162_D	0.849	0.93
146_K	196_T	0.848	0.93
360_S	364_P	0.847	0.93
420_C	446_E	0.844	0.93
251_Y	301_A	0.844	0.93
221_C	299_W	0.843	0.93
35_M	320_C	0.839	0.93
122_R	128_R	0.832	0.93
167_E	172_W	0.831	0.93
45_N	221_C	0.830	0.93
103_S	221_C	0.829	0.92
61_Q	67_H	0.829	0.92
168_H	171_T	0.829	0.92
177_G	187_A	0.828	0.92
49_Y	53_S	0.827	0.92
159_H	218_M	0.827	0.92
279_F	450_A	0.826	0.92
113_L	140_G	0.823	0.92
236_S	239_G	0.820	0.92
289_D	340_P	0.818	0.92
102_Y	120_N	0.817	0.92
90_L	115_L	0.817	0.92
293_R	339_L	0.816	0.92
28_H	454_P	0.816	0.92
396_F	428_V	0.814	0.92
234_I	239_G	0.813	0.92
392_A	458_N	0.813	0.92
87_E	141_L	0.813	0.92
280_D	303_P	0.811	0.92
56_V	83_W	0.809	0.92
283_A	299_W	0.807	0.91
418_R	421_R	0.807	0.91
298_A	447_V	0.805	0.91
250_V	302_V	0.802	0.91
300_M	440_F	0.801	0.91
383_G	395_S	0.799	0.91
227_L	329_L	0.799	0.91
231_D	238_Q	0.796	0.91
433_D	438_E	0.794	0.91
61_Q	71_F	0.793	0.91
61_Q	68_G	0.791	0.91
224_L	260_L	0.791	0.91
56_V	297_F	0.790	0.91
230_S	236_S	0.790	0.91
430_M	437_V	0.785	0.90
281_F	322_T	0.783	0.90
428_V	441_I	0.782	0.90
437_V	452_Y	0.781	0.90
94_D	97_D	0.780	0.90
381_E	468_K	0.779	0.90
256_F	267_L	0.777	0.90
234_I	275_L	0.776	0.90
259_R	268_K	0.773	0.90
97_D	145_K	0.772	0.90
114_Y	136_V	0.772	0.90
230_S	329_L	0.770	0.89
61_Q	70_K	0.769	0.89
30_Q	436_S	0.769	0.89
342_L	429_H	0.766	0.89
343_K	372_E	0.762	0.89
202_G	265_P	0.762	0.89
232_V	235_V	0.760	0.89
281_F	284_P	0.757	0.89
223_D	285_Q	0.757	0.89
381_E	386_I	0.756	0.89
354_I	357_H	0.755	0.89
220_E	299_W	0.755	0.89
375_L	428_V	0.752	0.88
378_I	385_S	0.752	0.88
64_Q	67_H	0.750	0.88
413_K	416_E	0.746	0.88
248_Q	251_Y	0.746	0.88
57_F	143_F	0.746	0.88
73_G	87_E	0.745	0.88
97_D	119_G	0.744	0.88
252_Q	274_E	0.744	0.88
262_Y	267_L	0.743	0.88
71_F	88_I	0.743	0.88
384_F	470_E	0.743	0.88
343_K	431_F	0.742	0.88
50_W	53_S	0.741	0.88
403_V	406_E	0.738	0.87
204_I	224_L	0.737	0.87
258_G	267_L	0.736	0.87
62_P	71_F	0.735	0.87
299_W	319_H	0.735	0.87
251_Y	302_V	0.733	0.87
375_L	386_I	0.733	0.87
57_F	74_H	0.733	0.87
28_H	435_S	0.733	0.87
166_W	262_Y	0.730	0.87
54_Y	80_V	0.728	0.87
249_N	252_Q	0.726	0.87
136_V	144_E	0.725	0.86
392_A	397_H	0.723	0.86
121_V	129_E	0.723	0.86
35_M	317_W	0.720	0.86
289_D	295_I	0.719	0.86
162_D	221_C	0.717	0.86
368_P	372_E	0.714	0.86
59_Q	72_W	0.713	0.86
82_N	344_A	0.712	0.85
357_H	360_S	0.712	0.85
385_S	389_R	0.710	0.85
338_P	431_F	0.707	0.85
252_Q	272_F	0.706	0.85
221_C	282_Y	0.705	0.85
230_S	234_I	0.704	0.85
439_I	448_L	0.703	0.85
59_Q	73_G	0.703	0.85
119_G	131_Y	0.702	0.85
173_Y	201_L	0.702	0.85
83_W	89_A	0.702	0.85
261_D	266_E	0.698	0.84
465_A	468_K	0.698	0.84
441_I	448_L	0.697	0.84
53_S	139_D	0.695	0.84
166_W	224_L	0.694	0.84
69_A	92_P	0.694	0.84
225_F	327_L	0.691	0.84
159_H	238_Q	0.691	0.84
63_F	69_A	0.690	0.84
67_H	102_Y	0.689	0.84
277_Q	421_R	0.688	0.83
338_P	342_L	0.688	0.83
166_W	170_G	0.688	0.83
276_D	298_A	0.686	0.83
59_Q	103_S	0.685	0.83
60_W	88_I	0.684	0.83
389_R	432_L	0.684	0.83
167_E	171_T	0.684	0.83
136_V	196_T	0.682	0.83
220_E	282_Y	0.681	0.83
355_N	358_G	0.680	0.83
384_F	396_F	0.680	0.83
462_T	465_A	0.679	0.83
388_I	392_A	0.673	0.82
403_V	422_I	0.673	0.82
45_N	299_W	0.673	0.82
42_N	299_W	0.672	0.82
234_I	238_Q	0.671	0.82
41_L	319_H	0.668	0.82
115_L	143_F	0.666	0.81
394_F	439_I	0.664	0.81
422_I	442_N	0.664	0.81
264_K	268_K	0.664	0.81
377_D	425_L	0.663	0.81
180_T	203_P	0.662	0.81
287_L	297_F	0.658	0.81
284_P	298_A	0.656	0.80
257_V	268_K	0.656	0.80
146_K	151_R	0.655	0.80
63_F	71_F	0.651	0.80
380_T	386_I	0.648	0.80
335_I	445_E	0.642	0.79
168_H	173_Y	0.641	0.79
133_C	150_A	0.641	0.79
351_K	362_A	0.640	0.79
410_F	416_E	0.639	0.79
385_S	395_S	0.639	0.79
130_T	160_F	0.639	0.79
297_F	321_M	0.636	0.78
102_Y	251_Y	0.636	0.78
105_S	165_V	0.635	0.78
81_V	345_M	0.635	0.78
53_S	84_K	0.635	0.78
295_I	326_Q	0.634	0.78
380_T	468_K	0.633	0.78
386_I	430_M	0.631	0.78
105_S	175_V	0.628	0.78
466_T	469_S	0.626	0.77
120_N	128_R	0.626	0.77
221_C	283_A	0.624	0.77
203_P	206_G	0.623	0.77
31_H	35_M	0.622	0.77
112_R	196_T	0.622	0.77
42_N	70_K	0.622	0.77
225_F	234_I	0.622	0.77
369_E	389_R	0.621	0.77
74_H	89_A	0.620	0.77
57_F	140_G	0.617	0.76
121_V	131_Y	0.617	0.76
442_N	446_E	0.616	0.76
109_K	195_L	0.615	0.76
54_Y	287_L	0.615	0.76
33_H	438_E	0.613	0.76
55_H	83_W	0.611	0.76
139_D	143_F	0.611	0.76
406_E	417_A	0.611	0.76
296_L	322_T	0.610	0.75
356_M	470_E	0.609	0.75
221_C	285_Q	0.606	0.75
275_L	296_L	0.604	0.75
96_F	149_V	0.604	0.75
129_E	158_A	0.603	0.75
263_N	267_L	0.602	0.75
45_N	283_A	0.602	0.75
165_V	192_S	0.602	0.75
130_T	303_P	0.600	0.74
381_E	385_S	0.599	0.74
383_G	464_S	0.598	0.74
417_A	421_R	0.598	0.74
54_Y	289_D	0.597	0.74
279_F	304_D	0.596	0.74
318_I	451_R	0.596	0.74
338_P	346_R	0.596	0.74
238_Q	304_D	0.595	0.74
417_A	420_C	0.595	0.74
359_S	365_V	0.595	0.74
85_R	88_I	0.594	0.74
312_T	453_F	0.594	0.74
397_H	401_G	0.593	0.73
57_F	113_L	0.592	0.73
42_N	45_N	0.589	0.73
418_R	422_I	0.589	0.73
32_F	338_P	0.589	0.73
57_F	141_L	0.587	0.73
32_F	440_F	0.585	0.72
330_S	337_Q	0.584	0.72
107_V	195_L	0.583	0.72
47_V	58_F	0.583	0.72
109_K	136_V	0.582	0.72
190_F	200_F	0.581	0.72
171_T	201_L	0.580	0.72
156_Y	203_P	0.580	0.72
165_V	198_W	0.579	0.72
42_N	102_Y	0.579	0.72
134_L	150_A	0.577	0.71
45_N	102_Y	0.577	0.71
57_F	139_D	0.577	0.71
161_R	282_Y	0.577	0.71
48_I	106_A	0.577	0.71
396_F	400_E	0.576	0.71
46_G	72_W	0.576	0.71
392_A	396_F	0.574	0.71
349_E	362_A	0.574	0.71
116_F	151_R	0.570	0.70
70_K	319_H	0.568	0.70
205_T	219_W	0.565	0.70
60_W	70_K	0.564	0.70
289_D	294_R	0.564	0.70
259_R	270_G	0.564	0.70
88_I	91_A	0.564	0.70
30_Q	317_W	0.564	0.70
418_R	450_A	0.564	0.70
403_V	439_I	0.563	0.70
42_N	62_P	0.562	0.69
380_T	385_S	0.562	0.69
80_V	287_L	0.562	0.69
249_N	418_R	0.562	0.69
379_H	385_S	0.560	0.69
68_G	71_F	0.559	0.69
396_F	426_H	0.559	0.69
267_L	270_G	0.558	0.69
54_Y	77_T	0.557	0.69
55_H	76_T	0.557	0.69
59_Q	67_H	0.557	0.69
249_N	274_E	0.557	0.69
267_L	271_E	0.556	0.69
396_F	401_G	0.556	0.69
403_V	420_C	0.556	0.69
100_G	120_N	0.555	0.68
239_G	249_N	0.555	0.68
255_Y	273_T	0.555	0.68
404_T	417_A	0.555	0.68
137_S	142_S	0.554	0.68
59_Q	70_K	0.554	0.68
392_A	406_E	0.554	0.68
86_E	89_A	0.554	0.68
32_F	370_R	0.553	0.68
362_A	365_V	0.553	0.68
298_A	323_L	0.553	0.68
320_C	451_R	0.551	0.68
357_H	363_L	0.551	0.68
57_F	76_T	0.550	0.68
463_A	466_T	0.549	0.68
234_I	253_S	0.548	0.67
43_D	161_R	0.547	0.67
281_F	286_T	0.546	0.67
122_R	126_G	0.546	0.67
205_T	213_D	0.545	0.67
48_I	53_S	0.545	0.67
233_L	238_Q	0.543	0.67
432_L	452_Y	0.543	0.67
45_N	59_Q	0.542	0.67
322_T	449_S	0.542	0.67
108_T	112_R	0.542	0.67
388_I	394_F	0.541	0.67
23_A	35_M	0.540	0.66
160_F	319_H	0.539	0.66
130_T	137_S	0.538	0.66
164_K	225_F	0.538	0.66
185_G	218_M	0.538	0.66
435_S	453_F	0.537	0.66
276_D	281_F	0.536	0.66
382_S	399_D	0.536	0.66
384_F	388_I	0.536	0.66
378_I	382_S	0.536	0.66
396_F	403_V	0.535	0.66
357_H	361_G	0.535	0.66
132_Q	145_K	0.535	0.66
62_P	92_P	0.535	0.66
291_Q	341_E	0.535	0.66
389_R	392_A	0.534	0.66
337_Q	429_H	0.534	0.66
43_D	220_E	0.534	0.66
461_V	464_S	0.534	0.66
156_Y	178_A	0.533	0.65
119_G	218_M	0.533	0.65
178_A	186_Q	0.533	0.65
26_D	316_H	0.533	0.65
221_C	236_S	0.532	0.65
46_G	285_Q	0.531	0.65
338_P	429_H	0.529	0.65
26_D	30_Q	0.529	0.65
103_S	299_W	0.529	0.65
166_W	173_Y	0.529	0.65
301_A	319_H	0.528	0.65
230_S	233_L	0.528	0.65
33_H	433_D	0.528	0.65
352_I	355_N	0.526	0.64
213_D	457_G	0.526	0.64
227_L	328_T	0.526	0.64
392_A	410_F	0.525	0.64
379_H	386_I	0.525	0.64
42_N	72_W	0.523	0.64
81_V	431_F	0.523	0.64
215_F	272_F	0.522	0.64
202_G	260_L	0.522	0.64
81_V	342_L	0.521	0.64
64_Q	69_A	0.521	0.64
40_L	299_W	0.521	0.64
361_G	365_V	0.521	0.64
42_N	221_C	0.520	0.63
102_Y	132_Q	0.520	0.63
435_S	454_P	0.520	0.63
192_S	255_Y	0.520	0.63
103_S	223_D	0.520	0.63
219_W	317_W	0.519	0.63
206_G	213_D	0.519	0.63
178_A	453_F	0.519	0.63
239_G	279_F	0.517	0.63
152_L	155_G	0.517	0.63
120_N	301_A	0.517	0.63
45_N	162_D	0.517	0.63
24_N	27_P	0.517	0.63
345_M	372_E	0.516	0.63
378_I	381_E	0.515	0.63
56_V	287_L	0.515	0.63
61_Q	66_G	0.514	0.63
197_E	200_F	0.514	0.63
455_F	458_N	0.512	0.62
234_I	237_P	0.512	0.62
113_L	137_S	0.512	0.62
134_L	151_R	0.512	0.62
42_N	71_F	0.511	0.62
118_T	220_E	0.511	0.62
115_L	137_S	0.511	0.62
289_D	292_G	0.511	0.62
359_S	363_L	0.508	0.62
159_H	217_Y	0.507	0.62
56_V	75_Y	0.505	0.61
42_N	61_Q	0.504	0.61
62_P	67_H	0.504	0.61
94_D	145_K	0.503	0.61
280_D	301_A	0.503	0.61
76_T	141_L	0.503	0.61
177_G	451_R	0.502	0.61
47_V	59_Q	0.502	0.61
42_N	67_H	0.502	0.61
152_L	157_T	0.501	0.61
64_Q	71_F	0.501	0.61
173_Y	260_L	0.501	0.61
41_L	58_F	0.500	0.60

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3pijA	2	0.9812	100	0.204	Contact Map
1y4wA	1	0.9269	100	0.211	Contact Map
3kf3A	2	0.9061	100	0.222	Contact Map
3ligA	2	0.9791	100	0.222	Contact Map
1w2tA	1	0.8727	100	0.225	Contact Map
4ffhA	1	0.8873	100	0.231	Contact Map
3sc7X	1	0.9123	100	0.231	Contact Map
2ac1A	1	0.9207	100	0.232	Contact Map
4eqvA	3	0.8998	100	0.234	Contact Map
1st8A	1	0.9248	100	0.237	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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