FUMC - BACSU - GREMLIN Contacts

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FUMC - Fumarate hydratase class II

UniProt:	P07343	Sequences: MEYRIERDTMGEVKVPADKFWGAQTQRSKENFKIGSEKMPMRVVKAFAILKRSTALANKRLGNLDAEKAEAIAAVCDDVLKGKYDDNFPLVVWQTGSGTQSNMNMNEVVANRATALLKEKNSDQTIHPNDDVNRSQSSNDTFPTAMHVAAVLAVYEQLVPALDQLRNTLDEKAKAYNDIVKIGRTHLQDATPLTLGQEISGWVHMLDRSKEMILEATDKMRALAIGGTAVGTGINAHPEFGELVSEEITKLTGQTFSSSPNKFHALTSHDEITYAHGALKALAADLMKIANDVRWLASGPRCGIGEIVIPENEPGSSIMPGKVNPTQSEALTMIAAQIMGNDATIGFAASQGNFELNVFKPVIIYNFLQSVQLLSDGMNSFHDKCAVGIEPNKETIQENLSNSLMLVTALNPHIGYENAAKIAKLAHKEGLTLKEAALKLELLTEEQFNEMVKPEDMVKPKA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	462 (402)
Sequences:	10894 (5824)
Seq/√Len:	290.5

ECOLI - FUMC ASPA ARLY PUR8
BACSU - FUMC ASPA ARLY PUR8
HALSA - FUMC ARLY Q9HS42
SULSO - FUMC Q980P8 ARLY

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
59_K	69_A	4.019	1.00
68_K	131_D	3.492	1.00
60_R	247_E	3.422	1.00
52_R	77_D	3.412	1.00
56_L	73_A	3.308	1.00
395_T	398_E	3.277	1.00
46_A	152_L	2.996	1.00
163_D	210_K	2.917	1.00
56_L	251_L	2.845	1.00
166_R	207_D	2.812	1.00
283_A	338_I	2.772	1.00
159_V	214_L	2.720	1.00
168_T	387_V	2.688	1.00
397_Q	401_S	2.688	1.00
154_V	275_A	2.669	1.00
42_R	372_Q	2.657	1.00
444_T	447_Q	2.631	1.00
156_E	217_T	2.622	1.00
341_N	370_S	2.541	1.00
159_V	210_K	2.534	1.00
219_K	274_Y	2.532	1.00
195_L	391_P	2.501	1.00
247_E	250_K	2.477	1.00
112_R	116_L	2.391	1.00
172_K	175_A	2.349	1.00
334_I	377_G	2.336	1.00
65_D	68_K	2.313	1.00
59_K	66_A	2.300	1.00
151_V	221_R	2.298	1.00
178_D	393_K	2.211	1.00
221_R	255_T	2.208	1.00
280_K	342_D	2.181	1.00
398_E	402_N	2.109	1.00
308_V	390_E	2.100	1.00
163_D	214_L	2.090	1.00
337_Q	366_N	2.068	1.00
66_A	70_E	2.066	1.00
161_A	379_N	2.046	1.00
166_R	210_K	2.037	1.00
431_L	439_K	1.992	1.00
171_E	387_V	1.991	1.00
247_E	251_L	1.977	1.00
168_T	382_H	1.963	1.00
171_E	175_A	1.963	1.00
395_T	399_N	1.957	1.00
425_L	429_E	1.950	1.00
284_A	339_M	1.948	1.00
290_A	331_L	1.924	1.00
210_K	214_L	1.917	1.00
168_T	386_A	1.911	1.00
215_E	219_K	1.886	1.00
212_M	274_Y	1.842	1.00
49_I	152_L	1.838	1.00
162_L	282_L	1.832	1.00
215_E	218_D	1.777	1.00
70_E	74_A	1.774	1.00
170_D	207_D	1.766	1.00
52_R	73_A	1.764	1.00
441_E	444_T	1.761	1.00
223_L	249_T	1.760	1.00
453_K	456_D	1.748	1.00
425_L	440_L	1.746	1.00
56_L	247_E	1.741	1.00
259_S	265_A	1.737	1.00
176_Y	179_I	1.728	1.00
418_N	421_K	1.724	1.00
286_L	331_L	1.722	1.00
222_A	257_S	1.717	1.00
382_H	387_V	1.703	1.00
166_R	203_V	1.693	1.00
393_K	397_Q	1.682	1.00
397_Q	455_E	1.677	1.00
164_Q	382_H	1.674	1.00
434_K	449_N	1.667	1.00
445_E	449_N	1.655	1.00
69_A	73_A	1.649	1.00
447_Q	450_E	1.641	1.00
209_S	285_D	1.632	1.00
208_R	264_H	1.613	1.00
225_I	244_V	1.601	1.00
431_L	436_A	1.581	1.00
52_R	80_L	1.561	1.00
438_L	445_E	1.554	1.00
273_T	349_A	1.541	1.00
227_G	265_A	1.523	1.00
344_T	362_V	1.522	1.00
161_A	375_S	1.505	1.00
57_A	247_E	1.504	1.00
246_E	250_K	1.502	1.00
173_A	203_V	1.483	1.00
245_S	249_T	1.466	1.00
172_K	176_Y	1.460	1.00
218_D	255_T	1.433	1.00
216_A	278_A	1.432	1.00
446_E	449_N	1.421	1.00
392_N	395_T	1.421	1.00
153_A	375_S	1.409	1.00
105_M	109_V	1.406	1.00
328_S	385_C	1.396	1.00
431_L	435_E	1.380	1.00
77_D	81_K	1.380	1.00
394_E	398_E	1.376	1.00
208_R	270_D	1.375	1.00
110_A	113_A	1.361	1.00
269_H	360_K	1.361	1.00
211_E	219_K	1.349	1.00
45_K	49_I	1.340	1.00
295_W	353_N	1.326	1.00
199_I	202_W	1.325	1.00
52_R	56_L	1.324	1.00
343_A	347_F	1.312	1.00
290_A	381_F	1.307	1.00
164_Q	387_V	1.303	1.00
418_N	442_L	1.302	1.00
170_D	174_K	1.302	1.00
280_K	346_G	1.299	1.00
273_T	281_A	1.295	1.00
150_A	275_A	1.293	1.00
166_R	206_L	1.292	1.00
432_T	435_E	1.287	1.00
112_R	115_A	1.285	1.00
277_G	281_A	1.284	1.00
179_I	393_K	1.274	1.00
42_R	153_A	1.274	1.00
71_A	74_A	1.269	1.00
45_K	80_L	1.265	1.00
168_T	171_E	1.265	1.00
159_V	217_T	1.263	1.00
202_W	355_E	1.257	1.00
47_F	141_T	1.257	1.00
37_E	369_Q	1.249	1.00
55_A	64_L	1.248	1.00
306_E	390_E	1.237	1.00
195_L	199_I	1.232	1.00
306_E	392_N	1.227	1.00
48_A	80_L	1.204	1.00
162_L	206_L	1.204	1.00
78_D	112_R	1.202	1.00
337_Q	369_Q	1.200	1.00
161_A	382_H	1.182	1.00
174_K	177_N	1.182	1.00
63_N	134_R	1.177	1.00
135_S	236_A	1.152	1.00
177_N	196_G	1.145	1.00
170_D	203_V	1.143	1.00
66_A	69_A	1.142	1.00
176_Y	393_K	1.137	1.00
331_L	377_G	1.137	1.00
213_I	282_L	1.135	1.00
159_V	163_D	1.129	1.00
48_A	105_M	1.129	1.00
45_K	84_Y	1.128	1.00
345_I	367_F	1.126	1.00
195_L	396_I	1.123	1.00
249_T	255_T	1.123	1.00
161_A	164_Q	1.122	1.00
163_D	167_N	1.118	1.00
78_D	83_K	1.117	1.00
70_E	73_A	1.108	1.00
48_A	79_V	1.107	1.00
135_S	237_H	1.106	1.00
53_S	251_L	1.100	1.00
150_A	367_F	1.099	1.00
151_V	254_Q	1.097	1.00
164_Q	379_N	1.096	1.00
414_I	419_A	1.093	1.00
189_D	300_P	1.091	1.00
202_W	289_I	1.086	1.00
293_V	328_S	1.085	1.00
77_D	80_L	1.083	1.00
106_N	109_V	1.075	1.00
272_I	367_F	1.070	1.00
211_E	218_D	1.066	1.00
335_A	339_M	1.061	1.00
413_H	447_Q	1.059	1.00
169_L	289_I	1.059	1.00
165_L	206_L	1.058	1.00
178_D	196_G	1.058	1.00
339_M	347_F	1.056	1.00
144_T	223_L	1.053	1.00
73_A	77_D	1.053	1.00
50_L	141_T	1.047	1.00
153_A	157_Q	1.046	1.00
181_K	396_I	1.045	1.00
71_A	75_V	1.041	1.00
192_P	400_L	1.040	1.00
200_S	261_N	1.038	1.00
429_E	436_A	1.034	1.00
287_M	332_T	1.029	1.00
60_R	251_L	1.029	1.00
340_G	344_T	1.025	1.00
75_V	78_D	1.024	1.00
41_M	85_D	1.022	1.00
46_A	148_V	1.020	1.00
146_M	364_I	1.018	1.00
154_V	217_T	1.016	1.00
165_L	386_A	1.015	1.00
278_A	282_L	1.013	1.00
172_K	386_A	1.005	1.00
221_R	254_Q	0.998	1.00
49_I	251_L	0.998	1.00
106_N	110_A	0.997	1.00
172_K	199_I	0.997	1.00
177_N	194_T	0.996	1.00
244_V	249_T	0.994	1.00
286_L	378_M	0.993	1.00
45_K	152_L	0.988	1.00
157_Q	375_S	0.985	1.00
146_M	272_I	0.979	1.00
59_K	70_E	0.976	1.00
154_V	213_I	0.976	1.00
412_P	447_Q	0.970	1.00
413_H	451_M	0.969	1.00
186_H	329_E	0.968	1.00
151_V	217_T	0.967	1.00
179_I	396_I	0.967	1.00
41_M	45_K	0.965	1.00
308_V	392_N	0.961	1.00
425_L	436_A	0.959	1.00
183_G	193_L	0.959	1.00
312_N	384_K	0.957	1.00
293_V	389_I	0.956	1.00
431_L	440_L	0.956	1.00
193_L	230_V	0.955	1.00
65_D	131_D	0.954	1.00
275_A	367_F	0.949	1.00
189_D	299_G	0.947	1.00
74_A	116_L	0.941	1.00
342_D	346_G	0.940	1.00
217_T	221_R	0.939	1.00
204_H	208_R	0.937	1.00
109_V	113_A	0.935	1.00
162_L	210_K	0.934	1.00
61_L	237_H	0.932	1.00
92_V	114_T	0.930	1.00
113_A	116_L	0.930	1.00
215_E	274_Y	0.927	1.00
276_H	345_I	0.927	1.00
307_I	389_I	0.922	1.00
295_W	354_F	0.921	1.00
50_L	144_T	0.920	1.00
42_R	152_L	0.913	1.00
435_E	439_K	0.911	1.00
67_E	70_E	0.909	1.00
89_P	92_V	0.907	1.00
113_A	126_I	0.903	1.00
211_E	215_E	0.900	1.00
223_L	248_I	0.898	1.00
169_L	199_I	0.897	1.00
91_V	94_Q	0.893	1.00
57_A	61_L	0.893	1.00
184_R	189_D	0.891	1.00
175_A	390_E	0.891	1.00
92_V	95_T	0.890	1.00
47_F	50_L	0.887	1.00
193_L	263_F	0.884	1.00
68_K	126_I	0.882	1.00
71_A	128_P	0.881	1.00
49_I	80_L	0.879	1.00
436_A	440_L	0.875	1.00
78_D	82_G	0.875	1.00
166_R	170_D	0.869	1.00
446_E	450_E	0.865	1.00
276_H	367_F	0.864	1.00
127_H	130_D	0.861	1.00
197_Q	262_K	0.861	1.00
81_K	85_D	0.860	1.00
337_Q	365_Y	0.857	1.00
78_D	124_Q	0.855	1.00
107_E	113_A	0.852	1.00
218_D	221_R	0.851	1.00
74_A	78_D	0.851	1.00
84_Y	112_R	0.850	1.00
303_G	395_T	0.849	1.00
400_L	454_P	0.848	1.00
448_F	452_V	0.848	1.00
284_A	349_A	0.847	1.00
49_I	248_I	0.844	1.00
198_E	355_E	0.842	1.00
46_A	149_A	0.841	1.00
82_G	112_R	0.837	1.00
276_H	342_D	0.836	1.00
173_A	200_S	0.835	1.00
179_I	391_P	0.835	1.00
189_D	403_S	0.833	1.00
90_L	93_W	0.833	1.00
78_D	116_L	0.832	1.00
152_L	156_E	0.830	1.00
434_K	445_E	0.828	1.00
434_K	438_L	0.826	1.00
204_H	260_P	0.824	1.00
169_L	203_V	0.821	1.00
76_C	79_V	0.821	1.00
68_K	72_I	0.820	1.00
187_L	295_W	0.820	1.00
307_I	388_G	0.819	1.00
167_N	171_E	0.818	1.00
146_M	367_F	0.818	1.00
180_V	400_L	0.818	1.00
203_V	207_D	0.814	1.00
168_T	172_K	0.812	1.00
365_Y	369_Q	0.811	1.00
169_L	386_A	0.809	1.00
437_A	440_L	0.808	1.00
194_T	458_V	0.806	1.00
110_A	114_T	0.803	0.99
425_L	439_K	0.801	0.99
228_T	318_I	0.800	0.99
78_D	84_Y	0.799	0.99
67_E	71_A	0.798	0.99
45_K	85_D	0.797	0.99
222_A	271_E	0.796	0.99
55_A	69_A	0.794	0.99
198_E	296_L	0.792	0.99
282_L	378_M	0.791	0.99
331_L	381_F	0.790	0.99
54_T	136_Q	0.789	0.99
187_L	298_S	0.789	0.99
341_N	369_Q	0.788	0.99
287_M	350_S	0.785	0.99
176_Y	391_P	0.783	0.99
289_I	381_F	0.776	0.99
277_G	342_D	0.775	0.99
401_S	434_K	0.769	0.99
106_N	113_A	0.768	0.99
339_M	343_A	0.767	0.99
59_K	64_L	0.766	0.99
184_R	300_P	0.766	0.99
268_S	285_D	0.764	0.99
60_R	66_A	0.762	0.99
421_K	425_L	0.762	0.99
267_T	355_E	0.761	0.99
57_A	244_V	0.759	0.99
441_E	445_E	0.754	0.99
208_R	222_A	0.754	0.99
274_Y	277_G	0.754	0.99
336_A	348_A	0.750	0.99
68_K	128_P	0.750	0.99
447_Q	451_M	0.749	0.99
90_L	94_Q	0.746	0.99
87_N	91_V	0.745	0.99
89_P	93_W	0.742	0.99
308_V	388_G	0.740	0.99
336_A	344_T	0.735	0.99
181_K	198_E	0.733	0.99
154_V	216_A	0.731	0.99
337_Q	341_N	0.730	0.99
222_A	259_S	0.729	0.99
224_A	265_A	0.729	0.99
104_N	109_V	0.728	0.99
47_F	105_M	0.728	0.99
258_S	262_K	0.726	0.99
310_P	388_G	0.722	0.99
56_L	60_R	0.720	0.99
270_D	285_D	0.715	0.99
162_L	378_M	0.715	0.99
82_G	87_N	0.715	0.99
426_A	429_E	0.714	0.99
344_T	366_N	0.714	0.99
343_A	346_G	0.713	0.99
72_I	128_P	0.713	0.99
109_V	112_R	0.710	0.99
290_A	328_S	0.709	0.99
246_E	249_T	0.707	0.99
263_F	355_E	0.705	0.99
180_V	458_V	0.703	0.99
296_L	354_F	0.703	0.99
175_A	393_K	0.703	0.99
385_C	389_I	0.702	0.99
275_A	372_Q	0.700	0.99
391_P	396_I	0.700	0.99
245_S	258_S	0.699	0.99
60_R	237_H	0.699	0.99
52_R	251_L	0.697	0.99
43_V	142_F	0.694	0.99
103_M	106_N	0.694	0.99
409_A	413_H	0.693	0.98
53_S	56_L	0.693	0.98
84_Y	87_N	0.692	0.98
201_G	288_K	0.691	0.98
341_N	371_V	0.691	0.98
182_I	302_C	0.690	0.98
436_A	439_K	0.689	0.98
275_A	279_L	0.689	0.98
421_K	440_L	0.688	0.98
80_L	84_Y	0.688	0.98
284_A	346_G	0.687	0.98
206_L	378_M	0.686	0.98
272_I	345_I	0.685	0.98
257_S	260_P	0.685	0.98
157_Q	161_A	0.685	0.98
303_G	392_N	0.685	0.98
111_N	115_A	0.684	0.98
179_I	194_T	0.683	0.98
114_T	129_N	0.683	0.98
79_V	109_V	0.682	0.98
169_L	206_L	0.681	0.98
102_N	310_P	0.680	0.98
64_L	134_R	0.680	0.98
348_A	362_V	0.679	0.98
339_M	346_G	0.678	0.98
158_L	371_V	0.676	0.98
287_M	351_Q	0.676	0.98
367_F	371_V	0.673	0.98
39_M	365_Y	0.673	0.98
94_Q	108_V	0.672	0.98
443_L	451_M	0.672	0.98
414_I	418_N	0.671	0.98
432_T	436_A	0.671	0.98
435_E	445_E	0.670	0.98
394_E	397_Q	0.670	0.98
221_R	249_T	0.669	0.98
72_I	76_C	0.669	0.98
308_V	311_E	0.668	0.98
147_H	271_E	0.668	0.98
206_L	209_S	0.667	0.98
154_V	159_V	0.667	0.98
264_H	270_D	0.663	0.98
223_L	258_S	0.663	0.98
205_M	285_D	0.661	0.98
167_N	170_D	0.659	0.98
212_M	270_D	0.656	0.98
378_M	382_H	0.655	0.98
52_R	69_A	0.654	0.98
199_I	396_I	0.653	0.98
37_E	365_Y	0.653	0.98
408_T	411_N	0.653	0.98
205_M	268_S	0.652	0.98
337_Q	373_L	0.652	0.98
225_I	248_I	0.652	0.98
289_I	386_A	0.652	0.98
420_A	424_K	0.650	0.98
163_D	207_D	0.648	0.98
438_L	448_F	0.647	0.98
158_L	375_S	0.646	0.98
128_P	131_D	0.646	0.98
344_T	348_A	0.646	0.98
104_N	107_E	0.644	0.98
56_L	69_A	0.642	0.98
88_F	94_Q	0.639	0.97
165_L	382_H	0.639	0.97
176_Y	195_L	0.638	0.97
156_E	254_Q	0.638	0.97
63_N	237_H	0.637	0.97
151_V	255_T	0.637	0.97
286_L	382_H	0.635	0.97
179_I	397_Q	0.635	0.97
151_V	156_E	0.633	0.97
178_D	455_E	0.632	0.97
163_D	166_R	0.632	0.97
171_E	174_K	0.632	0.97
395_T	402_N	0.631	0.97
291_N	332_T	0.630	0.97
154_V	220_M	0.629	0.97
107_E	110_A	0.628	0.97
149_A	371_V	0.628	0.97
410_L	448_F	0.628	0.97
59_K	73_A	0.626	0.97
299_G	303_G	0.626	0.97
327_Q	381_F	0.625	0.97
160_P	164_Q	0.622	0.97
455_E	459_K	0.622	0.97
284_A	350_S	0.620	0.97
181_K	193_L	0.620	0.97
280_K	284_A	0.618	0.97
401_S	432_T	0.618	0.97
108_V	113_A	0.618	0.97
282_L	374_L	0.617	0.97
114_T	125_T	0.617	0.97
182_I	400_L	0.616	0.97
86_D	89_P	0.614	0.97
248_I	251_L	0.614	0.97
287_M	347_F	0.612	0.97
209_S	281_A	0.612	0.97
164_Q	168_T	0.610	0.97
264_H	285_D	0.610	0.97
79_V	85_D	0.610	0.97
305_G	392_N	0.610	0.97
275_A	371_V	0.606	0.97
88_F	108_V	0.606	0.97
55_A	132_V	0.604	0.96
55_A	72_I	0.604	0.96
158_L	279_L	0.603	0.96
399_N	402_N	0.603	0.96
212_M	215_E	0.602	0.96
63_N	135_S	0.598	0.96
273_T	277_G	0.598	0.96
331_L	385_C	0.593	0.96
165_L	378_M	0.592	0.96
413_H	417_E	0.592	0.96
64_L	68_K	0.591	0.96
88_F	93_W	0.591	0.96
48_A	76_C	0.589	0.96
216_A	275_A	0.588	0.96
211_E	214_L	0.588	0.96
68_K	71_A	0.587	0.96
429_E	439_K	0.587	0.96
191_T	230_V	0.587	0.96
153_A	371_V	0.586	0.96
205_M	267_T	0.585	0.96
349_A	360_K	0.585	0.96
82_G	116_L	0.584	0.96
174_K	178_D	0.582	0.96
108_V	112_R	0.581	0.96
173_A	177_N	0.581	0.96
206_L	286_L	0.580	0.96
69_A	72_I	0.580	0.96
87_N	90_L	0.579	0.95
216_A	220_M	0.579	0.95
312_N	388_G	0.578	0.95
327_Q	385_C	0.578	0.95
279_L	374_L	0.577	0.95
202_W	205_M	0.577	0.95
105_M	110_A	0.577	0.95
212_M	219_K	0.576	0.95
172_K	389_I	0.576	0.95
107_E	112_R	0.575	0.95
273_T	345_I	0.574	0.95
107_E	111_N	0.573	0.95
206_L	282_L	0.571	0.95
332_T	359_F	0.569	0.95
64_L	72_I	0.568	0.95
183_G	230_V	0.568	0.95
366_N	369_Q	0.567	0.95
431_L	437_A	0.565	0.95
393_K	396_I	0.565	0.95
104_N	110_A	0.565	0.95
279_L	282_L	0.561	0.95
280_K	343_A	0.560	0.95
82_G	124_Q	0.560	0.95
125_T	128_P	0.559	0.95
170_D	173_A	0.559	0.95
400_L	405_M	0.557	0.94
425_L	431_L	0.556	0.94
211_E	222_A	0.556	0.94
94_Q	111_N	0.554	0.94
127_H	417_E	0.553	0.94
48_A	85_D	0.553	0.94
83_K	88_F	0.553	0.94
89_P	94_Q	0.553	0.94
283_A	374_L	0.553	0.94
229_A	318_I	0.548	0.94
108_V	111_N	0.548	0.94
209_S	212_M	0.547	0.94
131_D	134_R	0.546	0.94
162_L	213_I	0.546	0.94
46_A	49_I	0.546	0.94
158_L	374_L	0.545	0.94
159_V	278_A	0.544	0.94
189_D	405_M	0.543	0.94
181_K	296_L	0.543	0.94
450_E	456_D	0.543	0.94
277_G	280_K	0.542	0.94
42_R	157_Q	0.541	0.94
450_E	453_K	0.541	0.94
218_D	222_A	0.541	0.94
105_M	108_V	0.540	0.94
165_L	168_T	0.537	0.93
50_L	145_A	0.537	0.93
54_T	248_I	0.537	0.93
427_H	430_G	0.536	0.93
64_L	69_A	0.535	0.93
213_I	278_A	0.534	0.93
204_H	207_D	0.533	0.93
295_W	302_C	0.533	0.93
59_K	65_D	0.532	0.93
207_D	211_E	0.532	0.93
114_T	124_Q	0.532	0.93
82_G	85_D	0.531	0.93
364_I	368_L	0.531	0.93
49_I	53_S	0.530	0.93
291_N	351_Q	0.530	0.93
422_I	440_L	0.529	0.93
198_E	292_D	0.529	0.93
409_A	412_P	0.527	0.93
161_A	380_S	0.526	0.93
214_L	218_D	0.524	0.92
336_A	347_F	0.524	0.92
334_I	373_L	0.523	0.92
438_L	450_E	0.521	0.92
290_A	332_T	0.520	0.92
109_V	132_V	0.518	0.92
435_E	438_L	0.518	0.92
186_H	358_V	0.516	0.92
199_I	389_I	0.515	0.92
48_A	82_G	0.513	0.92
425_L	428_K	0.513	0.92
274_Y	281_A	0.513	0.92
216_A	274_Y	0.513	0.92
61_L	247_E	0.512	0.92
49_I	252_T	0.512	0.92
293_V	381_F	0.510	0.91
193_L	197_Q	0.509	0.91
417_E	421_K	0.509	0.91
65_D	69_A	0.508	0.91
150_A	220_M	0.508	0.91
313_E	326_T	0.508	0.91
438_L	449_N	0.508	0.91
55_A	73_A	0.507	0.91
279_L	338_I	0.505	0.91
244_V	248_I	0.505	0.91
81_K	84_Y	0.500	0.91
338_I	373_L	0.500	0.91

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1furA	4	0.987	100	0.118	Contact Map
1vdkA	4	0.987	100	0.122	Contact Map
1yfmA	4	0.9675	100	0.125	Contact Map
3gtdA	4	0.9827	100	0.138	Contact Map
4hgvA	4	0.9935	100	0.139	Contact Map
3r6qA	4	0.9913	100	0.139	Contact Map
3e04A	4	0.9935	100	0.142	Contact Map
1jswA	4	0.9827	100	0.143	Contact Map
4admA	4	0.9805	100	0.153	Contact Map
3ocfA	4	0.9654	100	0.156	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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